Abstract: The present invention teaches multiple three-dimensional nanosensing geometries for simultaneously assaying both large and small bio-related molecules in one device. The invention delivers broader sensitivity and selectivity than devices that assay small or large molecules separately. The combination assays all classes of molecules, e.g., proteins, lipoproteins, nucleoproteins, lipids, phospholipids, carbohydrates, nucleic acids, simple sugars, hormones, volatile organic compounds, drugs, drug metabolites, etc. Broad collection enables i) rapid and accurate diagnosis, ii) likely courses of treatments, and iii) timely feedback that monitors and follows the progressions of treatment(s). In one example, a patients pattern of blood lipids, proteins—including proteins with alternate cleavage patterns, peptides—including endocrine peptides, thyroxine (and/or other hormones), and drug metabolites, forms a profile specific to that patient at that time.

Abstract: Provided are an electrochemical gas sensor and a fabrication method therefor. A sensing electrode, a reference electrode and an auxiliary electrode in a planar arrangement are arranged on an upper layer in a sensor housing, and an electrolyte and a membrane material are arranged on a lower layer in the sensor housing. An upper part of the sensor housing is provided with a vent, and a lower part of the sensor housing is provided with a connector for connecting three electrodes and connected to an external circuit. Compared with the traditional cylindrical stacked electrochemical gas sensor, the fabrication method for a plate-body thin-film type sensor is simple, is less affected by the change of ambient pressure, temperature and humidity, and is beneficial to the flattening and miniaturization of electronic instruments and apparatus for gas analysis.

Abstract: Problem Provided is an electrolyte analyzer that allows reducing a load of a user in a replacement work compared with conventional one. Solution An electrolyte analyzer includes an ISE electrode 1 that includes at least one electrode, a reference electrode 2 that includes at least one electrode different from the ISE electrode 1, and a housing 200 that houses the electrodes of the ISE electrode 1 and the reference electrode 2. The housing 200 includes a pressing unit that presses the electrodes to one another, a first press switching unit 210 that switches the ISE electrode 1 between a secured state and a released state, and a second press switching unit 215 that switches the reference electrode 2 between a secured state and a released state. The ISE electrode 1 and the reference electrode 2 are each switched between the secured state and the released state. Selected Drawing: FIG.

Abstract: The present disclosure provides a novel method for producing a thin film in which the denseness of the thin film can be controlled. A method according to the present disclosure relates to a method for producing a thin film, including the steps (a) to (e) in this order: (a) providing an electrically conductive substrate; (b) using a first precursor to form a first layer on a surface of the electrically conductive substrate; (c) removing at least part of an unreacted material from the first layer; (d) electrochemically bonding a second precursor onto a surface of the electrically conductive substrate or to the first layer to form a second layer; and (e) repeating the steps (c) and (d).

Abstract: A capillary clip, a capillary electrophoresis apparatus, and a method for using a capillary clip. The capillary clip comprises a clip body, and a refrigerant channel, and at least two capillary channels defined by the clip body. The clip body comprises an inlet segment clip portion (100), a detection portion (200), and an outlet combination portion (300), wherein the inlet segment clip portion (100), the detection portion (200) and the outlet combination portion (300) are detachably connected in sequence in a sealed manner. The refrigerant channel and each capillary channel are combined at the inlet segment clip portion (100) and the outlet combination portion (300), and the refrigerant channel and each capillary channel are separated at a detection window (201) of the detection portion (200). A capillary (700) can be mounted in the capillary channel.

Abstract: A magnetic property acquisition unit detects an induced voltage caused by vibration of a measurement sample magnetized by an excitation electromagnet and acquires a magnetic property that indicates a relationship between a magnetic flux density and an external magnetic field. The magnetic flux density is a sum of magnetization of the measurement sample and the external magnetic field. When acquiring the magnetic property of the measurement sample to which pressure is being applied, a control device sets a first magnetic field value as a sweep start value, and performs sweeping with a magnetic field equal to or less than the first magnetic field value. The first magnetic field value is smaller than a second magnetic field value that is acquired before the pressure is applied to the measurement sample, and corresponds to a saturation magnetic flux density of the measurement sample to which the pressure is not being applied.

Abstract: Noise derived from electromagnetic coupling due to size reduction of an element mounting substrate is reduced. In an embodiment of the present disclosure, an element mounting substrate includes an insulation layer, an input wiring line and an output wiring line disposed on the insulation layer, and a ground layer disposed on the insulation layer, located around the input wiring line and the output wiring line, and including an exposed region where the insulation layer is exposed. The exposed region of the ground layer overlaps a region where the input wiring line and the output wiring line are close to each other. A SAW element is mounted on the element mounting substrate. With this configuration, the noise derived from the electromagnetic coupling generated between the input wiring line and the output wiring line can be reduced, and measurement accuracy can be improved.

Abstract: According to one embodiment, a structure evaluation system of an embodiment includes one or more sensors, a signal processing apparatus, and an evaluator. The plurality of sensors detect elastic waves generated from a structure. The signal processing apparatus calculates information on a frequency distribution by amplitude scale based on the plurality of elastic waves detected by each of the one or more sensors, and transmits the calculated information on the frequency distribution by amplitude scale in a wireless manner. The evaluator evaluates a state of deterioration of the structure based on the information on the frequency distribution by amplitude scale which is transmitted from the signal processing apparatus.

Abstract: According to one embodiment, a structure evaluation system according to an embodiment includes a plurality of sensors, a position locator, a corrector, and an evaluator. The plurality of sensors detect elastic waves generated from a structure. The position locator is configured to locate positions of sources of a plurality of elastic waves detected by the plurality of sensors on the basis of the plurality of elastic waves. The corrector is configured to correct information based on the position location in the position locator using a correction value which is determined according to a temperature of the structure. The evaluator is configured to evaluate a deterioration state of the structure on the basis of the corrected information.

Abstract: This disclosure describes methods and devices that assist in forming biosensors. Specifically, features that align solutions containing molecules to be immobilized on biosensors. A retaining structure may be disposed at least partially around a target surface of a substrate. A resonating structure may be disposed on the target surface. A droplet of functionalized material may be disposed on the resonating structure and the target surface, which may be auto-aligned and retained by the retaining structure on the target surface to consistently cover the resonating structure.

Abstract: A method for detecting internal coating defects in a pipe sample with an electromagnetic acoustic transducer sensor. The method includes recording a plurality of Lamb mode scans of the pipe sample with the EMAT sensor, where each Lamb mode scan is measured along a length of the pipe sample in axial alignment with the pipe sample; and processing the Lamb mode scans by applying a singular spectrum analysis to the Lamb mode scans to generate data from which the internal coating defects in the pipe sample are identified. The Lamb mode scans are at a frequency from dispersion curve of from 0.3 to 2 MHz, at a frequency of from 0.4 MHz to 2 MHz, a group velocity of from 1 mm/?s to 3 mm/?s, a phase velocity of from 5 mm/?s to 25 mm/?s, and a wave count of from 3 to 10.

Abstract: Systems, methods, and a computer readable medium are provided for determining a minimum geometric dimension of an indication of an object being inspected using ultrasonic data. The system can include a computing device configured to receive ultrasonic data from an ultrasonic inspection device and to determine a contour of at least one indication of a defect. The computing device can apply a geometric template figure to the determined contour such that the geometric template figure is enclosed by the contour. At least one minimum geometric dimension of the indication can be determined based on determining a maximum dimension of the geometric template figure enclosed by the contour. The computing device can provide the at least one minimum geometric dimension of the indication.

Abstract: Systems, techniques, and computer-implemented processes for calibration of transducers used for acoustic signal-based analysis are disclosed. In one aspect, a calibration method includes capturing a plurality of signals for a plurality of channels, each of the plurality of channels being associated with a pair of transducers formed of a transmitting transducer and a receiving transducer; and for each of the plurality of channels, determining a corresponding peak intensity for a corresponding signal of the plurality of signals; normalizing the corresponding signal based at least on the corresponding peak intensity to yield a corresponding normalized signal; and applying a time-shift to the normalized signal.

Abstract: A continuous field flow fractionator includes a sample inject port, a frit inlet port, a first fraction outlet port, a second fraction outlet port, and a third fraction outlet port. A first flow out of the first fraction outlet port is configured to extract a sample-free solvent. A second flow out of the second fraction outlet port is configured to extract an increased concentration of small molecules of a sample. A third flow out of the third faction port is configured to extract a remainder of the sample.

Abstract: A cryogenic trap for a thermal desorber includes a hollow quartz tube having a tube wall, a tube inlet, a tube outlet, and an interior passageway between the tube inlet and the tube outlet. A sorbent material is within the interior passageway, and a metal covering surrounds at least a portion of the quartz tube. The metal covering may be a metallic coating on an outer surface of the tube wall or a metal tube fitted around the quartz tube. The metal covering may be around a portion of the quartz tube adjacent the tube inlet and/or around a portion of the quartz tube adjacent the tube outlet. The metal covering may be around substantially an entirety of the quartz tube.

Abstract: There is provided a method of analysis of mass spectrometry data comprising obtaining raw experimental mass spectrometry data; performing a first deconvolution of the raw experimental mass spectrometry data using a deconvolution algorithm, a wide first input parameter set, and a wide first output parameter set to obtain a deconvolved output; obtaining discrete peak data from the deconvolved output; simulating raw data for a first peak of the discrete peak data to obtain reference simulated raw discrete data; simulating raw data for a second peak of the discrete peak data to obtain suspect simulated raw discrete data; and determining whether the second peak is likely an artefact or indicative of a mass by comparing the suspect simulated raw discrete data with the reference simulated raw discrete data.

Abstract: The present invention relates to the field of product quality analysis, and specifically, a test kit and detection method for testing isothiazolinone in textiles. A pretreatment step of the present invention adopts a unique process, which may fully transfer isothiazolinone to an acetone and water mixed solution, so that a more accurate measurement result can be achieved. The testing method of the present invention dose not add indicators, does not use large-scale analysis instruments, and is accurate in measurement, easy in reaction termination determination, high in accuracy, low in cost, and strong in popularization and application.

Abstract: A device and method for calibrating a delivery device includes providing a container A containing a nitrite, providing a container B containing an acid, releasing the contents of containers A and B, allowing the nitrite and acid to mix, waiting for a predetermined time, allowing air to combine with the mixture, and using NO and traces of NO2 to check and calibrate NO and NO2 sensors.

Abstract: The present invention brings an actual concentration of a process gas closer to an ideal concentration, and a gas analysis device that is used in a fluid control system that controls a process gas obtained by vaporizing a liquid material or a solid material, the gas analysis device including: a first concentration calculation unit that calculates a concentration of the process gas; a second concentration calculation unit that calculates a concentration of a by-product gas at least generated in a side reaction that is a reaction different from a main reaction for generating the process gas; a comparison unit that compares a first actual concentration that is the concentration of the process gas calculated by the first concentration calculation unit with a first ideal concentration, and compares a second actual concentration that is the concentration of the by-product gas calculated by the second concentration calculation unit with a second ideal concentration.

Abstract: The present invention relates to a gas monitoring device having an enhanced gas tight base unit containing a sensor. The base unit is detachably connected to an elongated hollow rod having a perforated tip end and a base unit connection end. The base unit comprises a sensor, a sealed gap, and a parts unit having a communication module (140) containing a telemetry unit with an antenna, a processor (145) and a circuit board (150). The invention also relates to a method of monitoring the gas concentration within a fumigated commodity sample comprising inserting the tapered perforated end of a gas monitoring device into a commodity sample.

Abstract: In various embodiments, both very high speed and very high sensitivity hydrogen detection is achieved by controlling water vapor concentration over the catalyst used to convert hydrogen in sample gas (e.g., ambient air) to water vapor, to provide a substantially stable water vapor mixing level at a target mixing ratio. The naturally-occurring water vapor in the sample gas, without further steps, typically would vary over time within a wide range (e.g., due to changing atmospheric conditions). By controlling a level of water vapor over the catalyst to be substantially equal to a target mixing ratio that is not too low as to impair response time, and not too high as to impair sensitivity, both very high speed and very high sensitivity can be provided.

Abstract: Antimony doped tin oxide-polypyrrole nano-composites for in situ and ex situ ppm level ammonia gas sensing at very low temperatures (room temperature to sub-zero ° C.). During synthesis, hydrogen peroxide (H2O2) has been used as a novel template for simultaneous oxidative polymerization of pyrrole as well as the polymer loading on doped metal oxide base. Usability of the above composition was tested for ppm level in-situ and ex-situ ammonia gas sensing in a very low temperature range (room temperature to ?30° C.). Stable and highly selective responses to ammonia gas were recorded in situ and ex situ at the very low temperature range (room temperature to ?30° C.). The revelation of very low temperature ammonia sensing property by the antimony doped tin oxide-polypyrrole nano-composite could be used for detecting meat and meat product spoilage under in situ and ex situ refrigerated conditions for cold storages and commercial preservations.

Abstract: Seed sensors for determining seed placement in a furrow to then target at least one of fluid and solid application with respect to the seed are described herein. Plant sensors for determining location of plants within a field and then targeting at least one of fluid and solid application with respect to the plant are also described herein.

Abstract: Seed sensors for determining seed placement in a furrow to then target at least one of fluid and solid application with respect to the seed are described herein. Plant sensors for determining location of plants within a field and then targeting at least one of fluid and solid application with respect to the plant are also described herein.

Abstract: Seed sensors for determining seed placement in a furrow to then target at least one of fluid and solid application with respect to the seed are described herein. Plant sensors for determining location of plants within a field and then targeting at least one of fluid and solid application with respect to the plant are also described herein.

Abstract: Seed sensors for determining seed placement in a furrow to then target at least one of fluid and solid application with respect to the seed are described herein. Plant sensors for determining location of plants within a field and then targeting at least one of fluid and solid application with respect to the plant are also described herein.

Abstract: Seed sensors for determining seed placement in a furrow to then target at least one of fluid and solid application with respect to the seed are described herein. Plant sensors for determining location of plants within a field and then targeting at least one of fluid and solid application with respect to the plant are also described herein.

Abstract: A process is hereby provided for monitoring the progress of pyrolysis reactions. Effluent from the pyrolysis reaction is fed to a catalytic reactor to catalytically combust the carbon in the pyrolysis exhaust gases to carbon dioxide. The CO2 is then subsequently measured. This allows for the efficient and accurate quantification of total organic carbon evolved from the reaction with time. This provides a more accurate surrogate for reaction progress than time or temperature. This technique is more accurate and provides faster response than other analytical techniques such as mass spectrometry and flame ionization detection. More accurate reaction monitoring allows for improved reaction control, optimization and the ability to utilize variable feedstocks.

Abstract: Systems, devices, and methods for localizing magnets are useful for biological tissue analysis and other applications. Tissue analysis systems for use with a tissue analysis device may include a storage medium storing computer readable instructions that cause the execution of magnet localization methods. The system may include the tissue analysis device, which includes a magnet and a magnetometer array disposed adjacent to the magnet. When executed by a processor, the instructions cause operations, including recording a magnetic field of the magnet with the magnetometer array, simulating a simulated magnetic field at each magnetometer of the magnetometer array, and estimating positional information of the magnet based upon iterating simulated positional information of the simulated magnet.

Abstract: The disclosure relates to a substrate comprising a micro- or nanostructured periodic array comprised of a plurality of anisotropic metallic micro- or nanostructures, wherein each of the plurality of nanostructures induce an average maximum and substantially uniform plasmonic field greater than 108 across the substrate; a plurality of Raman-active linker molecules directly bound to the metallic micro- or nanostructures; and a plurality of capture molecules directly bound to the Raman-active linker molecules. The disclosure also relates to systems, devices, and methods that use the substrates to determine the concentration of various analytes.

Abstract: The present technology relates to systems and associated methods for measuring properties of particles in a solution. In one or more embodiments, a particle measurement system is configured to generate a reference signal, communicate the reference signal across a plurality of resistors and overlapping pairs of electrodes that define detection regions for particulates traveling through a microchannel, and measure various properties of the particles based on detecting changes in the communicated reference signal.

Abstract: In one aspect, the disclosed technology relates to systems and methods for sequencing polynucleotides.

Abstract: The present disclosure provides an assay device for determining a concentration of hemoglobin in a sample. The device includes a separation membrane containing a cell lysing reagent that is present on the separation membrane in an amount greater than 200 micrograms/square centimeter to less than 675 micrograms/square centimeter. Further, the device includes a downstream detection membrane configured to elicit a quantifiable response in the presence of hemoglobin. The detection membrane includes an asymmetric membrane having a first plurality of pores located towards an upstream side of the detection membrane and a second plurality of pores located towards a downstream side of the detection membrane. The first plurality of pores are larger than the second plurality of pores. The present disclosure also provides methods for using a vertical flow assay device to lyse the red blood cells in the sample to quantify the level of hemoglobin present via reflectance spectroscopy.

Abstract: An acquisition control unit acquires spot urine nutritional component indexes of nutritional component indexes contained in one spot urine excreted by a human. The nutritional component indexes two or more selected from a sodium/potassium ratio indicating a ratio, a magnesium/creatinine ratio, an urea-nitrogen/creatinine ratio, and a sodium/creatinine ratio. The determination control unit compares the spot urine nutritional component index with a reference value preset for the spot urine nutritional component index for each of spot urine nutritional component indexes, and determines whether or not the spot urine nutritional component index is equal to or more than the reference value. The decision control unit decides a diet evaluation pattern indicating a balance of the diet of the human from the determination result for each of the determined spot urine nutritional component indexes. The output control unit outputs a diet evaluation comment improving the balance of the diet of the human.

Abstract: The present disclosure provides a quality control substance for use in the analysis of erythrocytes, which can be prepared safely with easily available raw materials, which has an excellent preservation stability, and which can be used in the analysis of sediments in a sample. This quality control substance includes artificial particles whose form as observed with a microscope is similar to the form of erythrocytes as observed therewith.

Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, maybe controlled via hydraulic pressure.

Abstract: Provided herein are methods of treating or preventing human cytomegalovirus (HCMV) infection comprising modulating interactions between the HCMV gH/gL/UL128-131A pentamer and plasma membrane-expressed host cell proteins, as well as methods of identifying modulators of such interactions.

Abstract: The present invention relates to a method for assessing respiratory viral infections, the method includes preparing one or more precision-cut human bronchial tissues; exposing a cilia-rich epithelium within the precision-cut human bronchial tissues to establish an ex vivo model of human bronchus for viral infections; assessing infectivity, tropism, and pathogenesis of one or more respiratory viruses in the ex vivo model; and providing a semi-quantitative and normalized approach to supplement data from the ex vivo model of human bronchus for pandemic risk assessment of the one or more respiratory viruses. The present invention involves micro-dissection of bronchial tissues to expose the cilia-rich epithelium for ex vivo virus infection, along with a semi-quantitative approach for analyzing virus tropism and replication competence.

Abstract: A tester includes: an inlet, connectable to an aspirator tube; an outlet connectable to a vacuum source; and a chamber between the inlet and the outlet, the chamber including: a first tester arranged such that fluids drawn into the chamber by the vacuum source come into contact therewith; a second tester arranged such that fluids drawn into the chamber by the vacuum source pass through it; and a reservoir between the first tester and the second tester; where the first tester includes a first substance adapted to change color in the presence of a target substance, and where the second tester includes colorimetric capnometer, which exhibits a color change in the presence of carbon dioxide, the in-line tester further including a liquid-stop device which, when dry, permits passage of gas from inlet to outlet, but when wetted by liquid, inhibits or prevents the passage of fluids from inlet to outlet.

Abstract: The present invention relates to a method for removing protein corona on the surface of nanometer particle. Specifically, the invention provides a method for removing protein corona of protein corona modified nanometer particle, the method comprises the following steps: subjecting the protein corona modified nanometer particle to ultrasound stimulation to remove the protein corona of the protein corona modified nanometer particle; the nanometer particle comprises perfluoropentane. Ultrasound stimulation can remove protein corona on the surface of nanometer particle, overcome the masking effect of the protein corona on the ligand modified on the surface of nanometer particle, and prevent the protein corona from blocking the binding of the ligand modified on the surface of nanometer particle to cell receptor.

Abstract: The invention is directed to a method for detecting a target moiety in a sample of biological specimens by the steps a) providing at least one conjugate with the general formula (I) Xn— P—Ym, with X is a detection moiety, P an acidic or basic degradable spacer and Y an antigen or oligonucleotide recognizing moiety and n, m are integers between 1 and 100 and wherein X and Y are covalently bound to P, b) binding the conjugate to the target moiety target via the antigen or oligonucleotide recognizing moiety Y, thereby labelling the target moiety, c) detecting the target moiety labelled with the conjugate by detecting the detecting moiety X, d) providing at least one precursor which is capable of releasing an acid or base when provided with radiation wherein the acid or base is capable of cleaving P, e) activating the precursor by providing radiation, thereby releasing the acid or base capable of cleaving P, and f) degrading spacer P with the released acid or base, thereby cleaving the detection moiety X from

Abstract: A method for detecting a target nucleic acid fragment in a sample includes a step of contacting the sample with a gRNA complementary to the target nucleic acid fragment, a Cas protein, and a substrate nucleic acid fragment, in which the Cas protein is immobilized on a solid phase, a substrate nucleic acid fragment is labeled with a fluorescent substance and a quencher, in a case of being cleaved by nuclease activity of a three-part complex of the Cas protein, the gRNA, and the target nucleic acid fragment, fluorescent light is emitted, the contact is performed in a reaction space having a volume of 10 aL to 100 pL, thereby forming the three-part complex in a case where the target nucleic acid fragment is present in the sample, cleaving the substrate nucleic acid fragment, and separating the fluorescent substance from the quencher; and detecting the fluorescent light, in which the detection of the fluorescent light indicates the presence of the target nucleic acid fragment in the sample.

Abstract: The present disclosure provides a method of fabricating a target capture and sensor assembly. The method comprises the steps of: providing a fluid path with a target capture surface comprising an anchor species with a first functional group disposed thereon; providing a target capture species to the target capture surface of the fluid path, wherein each target capture species comprises a target capture part and a second functional group configured to react with the first functional group; and exposing at least a portion of the target capture surface of the fluid path to photo radiation so as to cause a photo-initiated reaction between the first functional group and the second functional group, wherein the target capture and sensor assembly further comprises a sensing surface in the fluid path and wherein the target capture surface and the sensing surface are in fluid communication with one another.

Abstract: A method includes forming spherical liquid droplets of a first liquid phase containing a polymer precursor dispersed in a second liquid phase, where nanowires are located at an interface of the first and the second liquid phase and the nanowires extend with their longest axis substantially perpendicular to a surface of the spherical liquid droplets, and polymerizing the polymer precursor in the spherical liquid droplets to form beads including a solid polymer core and multiple nanowires aligned with their longest axis substantially perpendicular to a surface of the solid polymer core.

Abstract: Irritable Bowel Syndrome (IBS) is a multifactorial disorder characterized by pain, bloat, and changes in bowel movements, where different bacteria in the gut microbiome potentially influence some or all of the related symptoms. However, IBS is extremely heterogenous, suggesting a need to identify relationships between groups of bacteria in the gut microbiome and specific IBS-related symptoms. RS consumption significantly altered the microbiome while improving several measures of IBS. The use of RS by those needing to reduce the IBS-related symptoms, including those diagnosed with IBS, can be guided by simultaneously measuring changes in select genera in the microbiome.

Abstract: A device for determining presence or absence of infection due to an infectious agent is described. The device comprises a sample receiving zone configured to receive a liquid sample from a subject suspected of having an infection due to an infectious agent, the sample receiving zone positioned to distribute the sample along a first fluid flow path to a first label zone and along a second fluid flow path to a second label zone. Test lines in each fluid flow path capture a mobile detectable species as an indicator of presence or absence of the infectious agent. The device also comprises a reference line positioned in the one of the fluid flow paths. The bidirectional fluid flow paths emanate from a common sample zone and provide an efficient approach to detection and differentiate two species as indicators of the same infectious agent or as indicators of two different infectious agents.

Abstract: An apparatus for photonic biosensors for multiplexed diagnostics and a method of use are disclosed. The apparatus includes a portable device configured for point-of-care diagnostics. The portable device includes a photonic sensor chip that includes one or more resonators that is substantially in contact with at least a fluid that includes one or more analytes and the reader device communicatively connected to the photonic sensor chip that includes at least a light source and the reader device is configured to provide an input optical signal using the at least a light source, receive the one or more sensor signals from the photonic sensor chip and determine one or more characteristics of the one or more analytes as a function of the one or more sensor signals and a connecting system, wherein the connecting system is configured to connect the photonic sensor chip and the reader device.

Abstract: The invention relates to a method for in vitro diagnosis of a viral infection due to the presence of a vims in a subject, comprising a step of detecting at least one antigen specific for said vims by means of an immunological test carried out on a biological sample from said subject, characterized in that said biological sample consists of a combination of saliva and secretions from the anterior nasal vestibule of the subject.

Abstract: A method and a biosensor for determination of the presence of corona-virus are provided. The method includes qualitative or quantitative measurement of probable corona-virus presence by means of colorimetric and/or electrochemical transducer methods as a result of interaction of S-protein in patient samples by means of a biosensor including ACE2, DPP4 and CD147 bio-receptors as bio-receptor.

Abstract: Biomarkers to screen for, identify, and/or characterize lung cancer in a subject are disclosed. Also disclosed herein are methods for distinguishing lung cancer from another disease. Also disclosed herein are methods for detecting metastasis of a lung cancer in a subject. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.