Abstract: An adaptable working-channel apparatus comprising: at an external working channel attached at its proximal end to a first mounting coupling; a handle-mounting sleeve for surrounding an endoscope shaft or handle, and having on its radially outer peripheral side at least one second mounting coupling for releasable mounting engagement with the first mounting coupling. The first mounting coupling comprises two spring-loaded clamping branches that are hinged together like a clothes pin and each form a clamping portion and an actuation portion. The second mounting coupling has a mounting rail extending in the longitudinal direction of the handle-mounting sleeve and has or forms at least one undercut that can be interlockingly clasped by the clamping branches of the first mounting coupling. Also provided is a distal tissue-clip application adapter that is connectable to the adaptable working-channel apparatus; and a surgical equipping system, having the working-channel apparatus and tissue-clip application adapter.

Abstract: A controller for an auxiliary endoscope comprises a coupling piece for attaching to a main endoscope, a handpiece connected to the coupling piece, a working shaft extending from the handpiece and extending into the coupler and a first control feature located on the handpiece for operating a pull wire extending through the working shaft, the pull wire configured to steer the auxiliary endoscope, wherein the handpiece can be moved relative to the coupling piece to adjust a position of the auxiliary scope relative to the main scope.

Abstract: A manipulator system includes: a manipulator; a driving device to which the manipulator is detachably connected and which electrically drives the manipulator; a control device; a first sensor provided in the driving device; and a second sensor provided in the manipulator or the driving device. The control device is configured to perform a first step of confirming that the driving device operates normally according to electric power on the basis of an output of the first sensor, and a second step of confirming that the manipulator is connected to the driving device on the basis of an output of the second sensor. The first step includes checking whether the first sensor is normal, and the second step includes checking whether the second sensor is normal on the basis of the output of the first sensor that has been confirmed to be normal and the output of the second sensor.

Abstract: An endoscope comprises a handpiece housing, an elongate flexible shaft extending from the handpiece housing, a pull wire extending from the handpiece housing into the elongate flexible shaft, and a tensioning mechanism configured to adjust tension in the pull wire. A method for adjusting tension in a pull wire of a controller for an endoscope comprises preparing an endoscope for use before a procedure, adjusting tension in a pull wire for deflecting a flexible elongate shaft of the endoscope to reduce knob dwell, and performing an endoscopic procedure with the endoscope.

Abstract: A wireless imaging system comprising a head unit and a light cable is provided. The head unit comprises a head unit case, a head unit electrical connector, an image sensor, a wireless transceiver, a central processing unit, and a user-input component. The light cable comprises a light cable electrical connector, a power cable, and an integrated light source. The integrated light source comprises an emissive radiation source having a first spectrum, an optical element located to direct emissions from the emissive radiation source, a volumetric spectrum converter, and an optical reflector located about the converter. The converter converts emissions directed from the emissive radiation source to emissions having a second spectrum different from the first spectrum. The reflector reflects the converter emissions towards the output filter.

Abstract: With optical fiber-based illumination, uniform perceived illumination at an image capture device can be achieved with an input-angle-dependent intensity distribution at the input to the optical fiber. Disclosed are various apparatus and associated methods of operation that achieve such an angular intensity distribution, either statically or via programmable or controllable devices. Example embodiments utilize spatial intensity modulation of the light at a transform plane preceding the input to the optical fiber, light emission by multiple individually controllable emitters at different distances from or different angles relative to an optical axis, and/or beam sweeping across a range of input angles in synchronization with intensity control to generate the desired angular intensity distribution.

Abstract: Devices, systems and methods for cleaning a surface of as elongated instrument held within a cavity. In particular embodiments of the device, a longitudinal wire member extends along an elongated instrument (e.g. a laparoscope) and a rotatable transverse member removes matter from a surface of the instrument (e.g. a lens).

Abstract: A video data cable for use with a video medical device comprising an image capture device includes a processor; data storage; logic to identify the video medical device; logic to determine which of the video medical device or the data cable have a most up-to-date set of image capture settings based on the identified video medical device; logic to transmit the most up-to-date set of image capture settings to the video medical device when it is determined that the data cable includes the most up-to-date set of image capture settings; and logic to receive the most up-to-date set of image capture settings to the video medical device when it is determined that the data cable includes the most up-to-date set of image capture settings.

Abstract: A hysteroscopy system includes a scope having an internal channel, a sheath removably coupled to the scope, and an outflow channel. The sheath has a distal flange extending internally towards an outer surface of the scope. The outflow channel is formed between an inner surface of the sheath and an outer surface of the scope. The distal flange forms a distal end of the outflow channel and is generally located between the scope and the sheath.

Abstract: A proctoscope including a body, a handle extending therefrom and an elongated element, extended along an axis, with forward and aft ends and. The aft end attached to the body and open for interior access. At least one opening and/or a transparent section in the elongated element. A reference marking along the opening/transparent section and readable via the open aft end. A positioning device, to support at a treatment area, that includes an elongated position adjustment device, with a forward end contact surface, that is movably arranged substantially parallel to the axis and that extends from the body in the same direction as the elongated element from the body. Locking means arranged to secure the elongated position adjustment device in a selected position. The forward end contact surface to bear against the skin of a patient to maintain and support a position along the longitudinal axis at the treatment area.

Abstract: A device for evaluating the performance of visual equipment for a wearer. The device includes at least one input adapted to obtain virtual tests to be performed with the equipment, each test including at least one scenario combined with at least one virtual model of the wearer, defining how a visual task including a sequence of fixation points is to be carried out by the model in an environment defined by a description of shapes and positions of elements to be viewed by the model, at least one processor configured for selecting at least one test, based on at least one personalized real or simulated wearer activity profile representing usage of the equipment by the wearer, and evaluating the performance of the equipment with which the selected test is performed by the model by computing for one or more fixation points at least one performance criterion generated for the task.

Abstract: A device for evaluating visual equipment models corresponding to real visual equipments. The device includes at least one input adapted to obtain parameters including a prescription for a given human wearer of any one of the real visual equipments, a set of ophthalmic lenses pre-selected on the basis of those parameters, at least one processor configured, for each pre-selected ophthalmic lens, to obtain a visual equipment model including a virtual ophthalmic lens defined by the same characteristics as the pre-selected ophthalmic lens, obtain a wearer model from the parameters, the visual equipment model cooperating with the wearer model, obtain an environment and visual task model including a sequence of points to be looked at by the wearer model, and evaluate a performance of the visual equipment model worn by the wearer model and combined with the environment and visual task model.

Abstract: The system, method and device includes an optical coherence tomography (OCT) system switchable between single scan mode or multi-scan mode. This is achieved by use of multiple beam splitters to produce multiple OCT beams, but the system still uses a single light source, a single sample arm, and single reference arm to achieve a compact, more cost effective, system. Additionally presented is a spectral domain OCT system with a spectrometer having multiple grating, each providing a different depth and/or resolution imaging capability.

Abstract: Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.

Abstract: Face image processing, eye fatigue detection, statistical data collection and methods for myopia prevention are disclosed, such as face image processing that selects and generates face images of same size, such as eye fatigue detection that calculates the rate of spontaneous eye blink and compares it to a threshold that is based on statistical data and analysis, such as statistical data collection that collects data including but not limited to participants' age, blink rate records, visual acuity test results, and information about general reading or watching environment. The eye fatigue detection applies filter to improve the accuracy of eye blink detection and generates interruption request to stop near work when the blink rates exceeds the threshold. The accuracy of the threshold is guaranteed by the correlation in the statistical data.

Abstract: Systems, devices, and methods are described for assessing the risk of developmental, cognitive, social, or mental abilities or disabilities in very young patients (e.g., in the first 2-6 months of life). Generally, the decline in visual fixation of a subject over time with respect to certain dynamic stimuli provides a marker of possible abilities or disabilities (such as ASD). The visual fixation of the subject is identified, monitored, and tracked over time through repeated eye tracking sessions, and data relating to the visual fixation is then analyzed to determine a possible increased risk certain conditions in the subject. A change in visual fixation as compared to similar visual fixation data of typically-developing subjects or to a subject's own, prior visual fixation data provides an indication of a developmental, cognitive, or mental ability or disability.

Abstract: Disclosed is a method for defining a structure of an annular light guide device, for a fundus camera. An initial cross section of a wall of a light guide device is created in predefined way. A hollow cavity for a light source is defined within this cross section. The surface of the hollow cavity is an ellipsoid. Using a ray tracing software tool, the initial cross section is refined to maximise total internal reflection of the light from the source within the cross section to achieve most efficient light guide device. Once the final cross section is created, it is rotated by 360 degrees on a predefined axis to obtain final structure of the light guide device. The method is developed for creating very small light guide as required in a fundus camera especially for neonatal applications.

Abstract: A slit lamp microscope may include first and second arms rotatably provided on a main shaft; a microscope provided on the first arm and used to observe a subject's eyeball; a light source unit provided on the second arm and irradiating light including near-ultraviolet and visible light regions, including light with a wavelength of 405 nm, to the eyeball of a subject; a third arm rotatably provided on the main shaft; a camera provided on the main shaft and imaging the eyeball of the subject; an excitation filter that transmits only light with a wavelength of 405 nm that induces a fluorescence reaction in stained goblet cells among the light irradiated from the light source unit to the eyeball of the subject; and a light receiving filter that transmits only the light fluorescently reacted in the goblet cells among the light received by the camera.

Abstract: A device for capturing EEG signals comprises a flexible wireless sensor configured to be adhesively attached at an EEG measurement point of a user's head, and configured to be remotely powered and to transmit, via a first radio frequency link, EEG data corresponding to samples of a measured EEG signal; a base station located near the sensor, configured to remotely power the sensor; and a terminal configured to receive transmitted EEG data.

Abstract: The present invention provides medical imaging apparatus comprising a primary module for imaging a patient and a supplemental module. A controlling circuitry activates the supplemental module shortly before, during, or shortly after an imaging process using the primary module. Information, data or images of the patient acquired with the supplemental module is registered to the primary image. The invention can aid a radiologist to avoid confusion, mismatching, and other errors when he is reading the primary image; and can help a doctor to establish a correlation between conditions revealed by the primary image, and cutaneous conditions and anatomical change revealed by the supplemental module.

Abstract: Disclosed is a near-infrared imaging optode (200) and associated system and method for transmitting near-infrared radiation into and/or receiving near-infrared radiation from a subjects head. The optode (200) comprises a plurality of resilient optical fibres (201) arranged to transmit and/or receive corresponding near-infrared radiation. The plurality of optical fibres (201) each comprise a distal end (203) arranged to make contact with a subjects head. The distal ends (203) of the plurality of optical fibres (201) are movable relative to each other.

Abstract: Disclosed herein are methods for delivering a drug to the brain of a subject and monitoring the distribution of the drug therein. The method includes steps of: (a) intranasally administering of a first and second liposomes respectively loaded with the drug and a computed tomography (CT) contrast agent therein to the subject; (b) subjecting the brain of the subject of step (a) to a magnetic resonance imaging (MRI) scan; and (c) measuring chemical exchange saturation transfer (CEST) signals during the MRI scan in both olfactory bulb (OB) and frontal lobe (FL) regions at 1.2 ppm, 4.3 ppm, and ?3.4 ppm, respectively.

Abstract: Disclosed are methods and digital tools for deriving tooth condition information for a patient's teeth, for populating a digital dental chart with derived tooth condition information, and for generating an electronic data record containing such information.

Abstract: The present disclosure relates to a calibration cradle for a three-dimensional scanner. In particular, the calibration cradle includes: a fixed case having an internal space formed therein; a pattern plate provided inside the fixed case and provided to calibrate the three-dimensional scanner comprising a camera; a movable case into which at least a portion of the three-dimensional scanner is inserted such that the camera faces the pattern plate, the movable case being configured to move to allow the three-dimensional scanner to move by at least one of rotational movement or vertical movement; and a movement driver configured to provide a driving force to move at least one of the movable case or the pattern plate. The calibration cradle provides an advantage of improving the reliability of calibration and user convenience.

Abstract: A method for determining a concentration of a target gas in blood of a human or animal animate being. The method includes the steps of: generating electromagnetic excitation radiation having a carrier frequency, wherein the carrier frequency is selected such that the target gas and an absorbing gas absorb the excitation radiation, modulating an amplitude or the carrier frequency of the excitation radiation with a modulation frequency, illuminating an absorption path superficial to a skin of the animate being with the excitation radiation, generating a sound wave by an absorption of the excitation radiation in the absorption gas, and detecting at least one of an amplitude and a phase of the sound wave as a measure of a concentration of the target gas on the absorption path. Also provided is a photoacoustic sensor for determining a concentration of a target gas in blood of a human or animal animate being.

Abstract: A robotic system includes retrieval of a priori stimulus based on an input that indicates a current health state and a target health state of a user. A set of test stimuli specific for the user is determined and a stimulus device is controlled to provide the set of test stimuli to the user. A set of responses within the body of the user is determined, and a set of stimulus parameters for the stimulus device is calibrated based on the combination of the set of responses, the current health state, the target health state, and a trained AI-based system. A new stimulus is applied to a portion of the body of the user that shifts a condition of the user from the current health state towards the target health state.

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

Abstract: The present invention discloses a system and method for non-intrusive monitoring and prediction of cardiac function of a user. The system (100) comprises a sensor device (102), a data capturing device (104), a data receiver module (106), an acoustic engine (108) and user devices (110), which communicate by using communication network (112). The sensor device (102) comprises a sensor array to capture micro-vibrations of physiological parameters of a user through a surface/mattress under which the sensor device (102) is positioned. The acoustic engine (108) converts the digital time-based vibration signals into frequency-based acoustic outputs such as physiological condition acoustic signals. Further, the acoustic engine (108) is configured to determine the user's current and future health issues based on the physiological condition acoustic signals. does not require trained medical practitioners to analyze the vibration signal of the user to determine the physiological conditions of the user.

Abstract: A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.

Abstract: A system for measuring at least one physiological parameter includes a wearable device configured to be secured to a subject's foot and a camera configured to captures images of the subject. An electronic device may be in communication with the system and can display information relating to physiological data and/or images collected by the system.

Abstract: According to an aspect, there is provided a computer-implemented method for analysing a pulse wave signal, PWS, obtained from a subject to determine an indication of the blood pressure or a change in blood pressure of the subject. The PWS comprises pulse wave measurements for a plurality of cardiac cycles of the subject during a first time period.

Abstract: A measuring device includes a first space for pressurizing a pressurization target and a second space independent of the first space. The measuring device includes a first exhaust valve closing or opening a communication port communicating the first space with another space. An open/closed state of the first exhaust valve changes in accordance with a pressure difference between the first space and the second space.

Abstract: A system and method are provided for determining a pressure associated with a lumen of a body. A wireless sensor is positioned in the lumen of the body. The sensor comprises an LC resonant circuit having a resonant frequency configured to vary in response to changes in pressure in the lumen. One or more sensor calibration parameters are stored at an external base unit. The external based unit generates and transmits an energizing signal. A ring down response is received from the wireless sensor. The system and method determine the resonant frequency of the LC resonant circuit from the ring down response and calculate the pressure in the lumen from the resonant frequency of the LC resonant circuit utilizing the one or more sensor calibration parameters associated with the LC resonant circuit.

Abstract: An intravascular data analysis system to assess a blood vessel includes: an interface system configured to receive intravascular pressure data including a plurality of distal pressure (Pd) values measured by an intravascular data collection probe and a plurality of proximal pressure (Pa) values; a display system; one or more memory storage devices includes instructions; and a processor in communication with the interface system, the display system, and the one or more memory storage devices. The processor is configured to execute the instructions to: determine a plurality of Pd/Pa ratios based on the plurality of distal pressure (Pd) values and the plurality of proximal pressure (Pa) values, filter the plurality of Pd/Pa ratios using a filter having a time constant TC in a range of 1% to 50% of a heart cycle length, and control the display system to generate a plot based on the plurality of Pd/Pa ratios.

Abstract: Provided are a method for determining an equivalent speed, an apparatus, a device, and a storage medium. The method includes the steps described below. The heart rate-speed relationship of a user in a standard environment is acquired. A first heart rate and a first speed of the user are acquired. An equivalent speed of the user in the standard environment is determined according to the first heart rate, the first speed, and the heart rate-speed relationship. The method for determining an equivalent speed disclosed in the present invention converts the current speed of a user into an equivalent speed in a standard environment by using the heart rate-speed relationship in the standard environment.

Abstract: To stably obtain biometric information, such as a respiratory rate and a heart rate, from a time waveform indicating a change in phase of a Doppler signal, provided is a biometric information detection system including: an arctangent demodulation module which acquires a time waveform indicating a change in phase of a Doppler signal acquired by receiving a wave reflected from a person to be measured; a unit waveform acquisition module which acquires a plurality of unit waveforms from the time waveform; a reference waveform generation module which generates a reference waveform based on the plurality of unit waveforms; a waveform correction module which corrects the time waveform based on the reference waveform; and a biometric information acquisition module which acquires biometric information based on the corrected time waveform.

Abstract: A physiological signal measurement system, a physiological signal measurement method, and a mobile device protective case are provided. The physiological signal measurement system includes a first electrode, a second electrode, a reference electrode, an impedance front-end circuit module and a dynamic signal matching module. The first electrode, the second electrode and the reference electrode are used to obtain a first sensing signal and a second sensing signal. The impedance front-end circuit module is used to detect a first impedance of the first electrode and a second impedance of the second electrode, and obtain an original differential signal according to the first sensing signal and the second sensing signal. The dynamic signal matching module is used to obtain a calibration sequence according to the first impedance, the second impedance and the original differential signal, and obtain a compensated calibration sequence according to the calibration sequence and the original differential signal.

Abstract: A tomographic system accurately determines characteristics of a specific region within an inhomogeneous dielectric specimen by guiding an electromagnetic field through the inhomogeneous dielectric specimen in a transverse mode. The system may include a source of electromagnetic energy for generating an electromagnetic waveform, and a transmission line for guiding an electric field of the waveform along a prescribed path that defines a series of spatial regions. The transmission line is provided by a pair or array of conductors, the electric field spanning between two or more of the conductors as the electric field propagates along the prescribed path. The conductors may form part of an external non-contact structure which guides and controls the electromagnetic field both spatially and temporally.

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

Abstract: A method for determining a position of a catheter tip of a catheter, more particularly of a central venous catheter, in the body of a patient, a medical system equipped to carry out such a method, and the use of the method in catheterization.

Abstract: Sensors are disclosed that detect whether a cannula is properly inserted to its full depth in a subject's skin. The sensors may be used with a blood glucose monitor, or with a continuous insulin infusion pump, infusion set, or other system involving intermittent or continuous testing and/or drug delivery.

Abstract: One embodiment is a method of performing thoracic tomography on a human subject including performing multiple 4-wire impedance measurements on a region of interest to obtain measured impedance data; comparing the measured impedance data to simulated impedance data obtained from a plurality of models of the region of interest; for each of the models, determining a fit of the model based on a comparison between the simulated impedance data obtained from the model and the measured impedance data; and integrating individual resistivity estimates obtained from the models based on a fit of the model such that the individual resistivity estimate from a better fitting model is weighted more heavily in a final resistivity estimate than an individual resistivity estimate from a worse fitting model.

Abstract: Methods and devices for analyzing non-volatile organics in exhaled breath and other aerosols using various diagnostic tools that enable rapid, low-cost point of care assays for several diseases including respiratory tract diseases such as COVID-19. The disclosed methods and systems selectively capture non-volatile organics in exhaled breath and other aerosols in a packed bed column. The non-volatile organics are eluted and samples are analysis using diagnostic devices including MALDI-TOFMS. The disclosed systems and methods provide for a diagnostic test result in less than about 20 minutes and provides for autonomous operation with minimal human intervention.

Abstract: A method for counting coughs is provided. The method includes acquiring a plurality of onset signals from the sound signal, wherein the onset signal has a predetermined time length; acquiring a plurality of spectrograms corresponding to each of the plurality of onset signals; determining whether each of the acquired plurality of spectrograms represents a cough using a cough determination model; and calculating a number of coughs included in the sound signal based on a time point of a cough signal. The cough signal is an onset signal corresponding to one spectrogram determined to represent the cough. When a time interval between a first time point of a first cough signal and a second time point of a second cough is within a reference time interval, the first cough signal and the second cough signal are regarded as one cough signal at the first time point.

Abstract: A method comprising: receiving, with respect to each of a plurality of subjects, data comprising at least one of: (i) a data representing center of pressure (COP) of a subject during at least on gait phase; (ii) a data representing center of gravity (COG) of the subject during at least on gait phase; and; (iii) a data representing posture of the subject during at least on gait phase; processing the data to extract a plurality of features representing the data, at a training stage, training a machine learning model on a training set comprising all of the plurality of features; and at an inference stage, applying the trained machine learning model to a target set of the features obtained for ma target subject, to classify posture, proprioception and/or kinesthesis of the target subject.

Abstract: An anomaly detection device that includes an extraction unit that acquires sensor data from a sensor installed in footwear and extract a gait feature amount characteristic in gait of a pedestrian wearing the footwear by using the sensor data, and a detection unit that detects an anomaly in a foot of the pedestrian walking wearing the footwear based on the gait feature amount extracted by the extraction unit.

Abstract: An apparatus for monitoring neural response and/or providing treatment includes an electrical stimulator configured to apply electrical stimulation, and one or more processors configured to analyze stimulation response. The one or more processors can be further configured to operate the electrical stimulator, adjust the electrical stimulation, and determine one or more wound characteristics based at least in part on at least one of the electrical stimulation or the stimulation response, e.g. a movement of a patient, a color absorption characteristic, or other physiological responses. An indication of the one or more wound characteristics can be provided.

Abstract: In order to calculate, with a high degree of accuracy, step lengths for both feet on the basis of a physical quantity relating to the movement of one foot, this calculation device includes: a detection unit that generates a walking waveform using sensor data and detects a walking event from the generated walking waveform, the sensor data being based on a physical quantity that is measured by a sensor positioned on one foot of a walker and relates to the movement of the foot; and a step length calculation unit that calculates the step lengths for both left and right feet on the basis of the timing of the detected walking event.

Abstract: In order to calculate, with a high degree of accuracy, step lengths for both feet on the basis of a physical quantity relating to the movement of one foot, this calculation device includes: a detection unit that generates a walking waveform using sensor data and detects a walking event from the generated walking waveform, the sensor data being based on a physical quantity that is measured by a sensor positioned on one foot of a walker and relates to the movement of the foot; and a step length calculation unit that calculates the step lengths for both left and right feet on the basis of the timing of the detected walking event.

Abstract: In order to detect a detailed walking event in both legs on the basis of a physical quantity that relates to leg motion measured by a sensor mounted on one leg, there is provided a detection device including: an extraction unit for generating time-series data that accompany walking, using sensor data based on a physical quantity that relates to leg motion measured by a sensor installed on one leg part of a walking person, and extracting a walking waveform from the generated time-series data; and a detection unit for detecting a walking event in both legs of the walking person from the walking waveform extracted by the extraction unit.