Abstract: An adaptor for a syringe including a shaft with a lumen and a seal. The shaft is sized and shaped to be inserted in the lumen of the syringe tip and create a seal with the opening of the syringe tip, and the seal is sized and shaped to be inserted into the needle hub and create a seal with the needle hub, such that the adaptor reduces the interior volume of the lumen of the syringe tip and the needle hub that is filled with medicament contained in the syringe. Also, an adaptor assembly comprising the adaptor and a delivery housing to which the adaptor is attached, a syringe body including the adaptor, a needle assembly including the adaptor, and a syringe including the adaptor. Further, a method of reducing the dead volume of a syringe in which the adaptor is provide in the syringe as described above.

Abstract: A stopper for a multi-chamber syringe includes a body having a first end surface, a second end surface, a peripheral surface extending between the first end surface and the second end surface, and at least one slit extending through the body for permitting fluid flow through the body of the stopper. The stopper also includes a first barrier film adhered to the first end surface of the body and a second barrier film adhered to the second end surface of the body. The first barrier film and/or the second barrier film comprise slits or openings aligned with the slit extending through the body for permitting fluid flow through the stopper. A multi-chamber syringe including the stopper and a method of making the stopper are also provided herein.

Abstract: Systems and methods for delayed delivery of a drug are disclosed. A drug delivery system may include a delivery member for insertion into a patient and a reservoir configured to receive a volume of a drug. An energy source may be activatable by the patient to actuate the reservoir to deliver the drug to the patient as a single bolus. A lockout system may be configured to have a locked state, wherein the lockout system prevents movement of the delivery member and/or activation of the energy source, and an unlocked state, wherein the lockout system permits movement of the delivery member and/or activation of the energy source. The lockout system may be configured to automatically change from the locked state to the unlocked state after a preselected time period has elapsed. An output element may generate a detectable output after the preselected time period has elapsed for notifying the patient.

Abstract: Described is an autoinjector comprising of a case, a motor adapted to rotate a drive gear, and a curvi-linear plunger adapted to mate with the drive gear. The plunger includes a distal end with a resilient flange, which in a non-deflected state, abuts a proximal collar of a syringe, and, in a deflected state, advances through the proximal collar and engages a stopper in the syringe.

Abstract: A method of controlling a temperature of a biopharmaceutical product during blow-fill sealing, includes developing a model based on heat transfer mechanisms that incorporates the effects of the blow-fill sealing on the biopharmaceutical product, providing a parison to a blow-fill sealing machine for accepting the biopharmaceutical product during the blow-fill sealing, predicting a temperature of at least one the biopharmaceutical product, the parison, and a component of the blow-fill sealing machine at a stage in the blow-fill sealing, and adjusting a parameter of the blow-fill sealing machine to reduce damage to the biopharmaceutical product.

Abstract: A cartridge is configured to receive an injectable drug. The cartridge includes a body, and the body includes a proximal end portion having a proximal opening, a distal end portion having a distal opening, and a bore coupling the proximal opening and the distal opening. The cartridge further includes a pierceable septum coupled to the distal opening and a plunger movably carried within the bore. A volume is disposed in the bore between the pierceable septum and the plunger. The volume has a reduced pressure, and the reduced pressure is less than atmospheric pressure. A stopper is detachably coupled to the distal opening.

Abstract: An injection apparatus, including: a needle configured to be inserted into a tissue; a light source to deliver light to the tissue to generate reflected light; a detector to detect the reflected light from the tissue; a processor coupled to the detector and configured to: analyze the reflected light from the tissue to identify a tissue type associated with the reflected light, and provide an output to a user based on the identified tissue type.

Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.

Abstract: Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

Abstract: A drug delivery drive mechanism including a ratchet wheel including a plurality of teeth, a ratchet arm including a first prong and a second prong, wherein the first prong is operable interact with a tooth of the plurality of teeth to rotate the ratchet wheel in a circular direction, and the second prong is operable to interact with another tooth of the plurality of teeth to further rotate the ratchet wheel in the circular direction.

Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Abstract: A system includes a first cavity with an open upper proximal end and a distal end including a plurality of ports. A second cavity can be concentric with and advanceable through the open upper proximal end of the first cavity. The second cavity can include an open upper proximal end. A plunger can be on a distal end of the second cavity. The plunger can be configured to move a first constituent from the first cavity through at least one of the plurality of ports. A plunger rod can be advanceable through the open upper proximal end of the second cavity and configured to move a second constituent from the first cavity through at least one of the plurality of ports.

Abstract: A cap for a syringe with Luer-lock connector comprising: a main body provided with a first handle portion and a second portion having an external threading for coupling with a corresponding internal threading of the Luer-lock connector of the syringe, an axial cavity having an aperture at the second coupling portion being formed in the main body; and a rubber housed in the axial cavity of the main body. The rubber has a surface facing the aperture of the axial cavity and designed to abut against an open free end of a tip of the syringe for air-tightly closing the open free end and raised elements are formed at the external threading of the second coupling portion.

Abstract: A device that includes a sheath, wherein the sheath includes an opening configured to receive a container; a connector conduit, a first end of the connector conduit operably connected to the sheath, a connector rod, wherein a second end of the connector conduit, the second end of the connector conduit opposite the first end of the connector conduit, is operably connected to a first end of the connector rod; and a clamp, wherein a second end of the connector rod, the second end of the connector rod opposite the first end of the connector rod, is operably connected to the clamp, and wherein the clamp is configured to extend at least partially around the perimeter of a syringe barrel.

Abstract: An injection device for injecting medicament in a patient includes a syringe coupled to a housing and radially retained by a retaining rib. A needle guard is slideably coupled to the housing and spring biased in a distal direction by a return spring. A ram is slideably coupled to the housing and spring biased in the distal direction by a main spring. An initial position is defined by a retaining arm being disposed in the longitudinal path of the ram preventing firing. A released position is defined by the retaining arm being clear from the longitudinal path of the ram allowing the ram to extend distally. A locked position is defined by the retaining arm being disposed in the longitudinal path of the ram and a lock arm of the ram being disposed in the longitudinal path of the needle guard preventing the needle guard from being retracted.

Abstract: An insertion mechanism for a cannula includes a cannula housing, a displaceable cannula, at least one cannula holder, an insertion spring, a triggering element, and a safety device. The safety device, in a secured state, holds the triggering element in a blocked position against a force of the insertion spring and, in a released state, releases the triggering element such that the triggering element is movable into a release position by the force of said insertion energy store and the at least one cannula holder is able to move relative to the cannula housing, driven by the insertion energy store, so as to trigger or implement an insertion movement or insertion. To reach the released state, the safety mechanism is heatable by a heating element and softened and/or weakened with respect to its mechanical carrying or holding capacity, or severed or at least partially or completely melted.

Abstract: A medical device includes a handle having a first end and a second end, a mixer positioned within the handle and an adapter coupled to the second end of the handle. A delivery needle includes a distal end, a proximal end, and a lumen extending from the distal end to the proximal end. The proximal end of the delivery needle is coupled to the first end of the handle. A sensor cable includes a distal end and a proximal end, and the proximal end of the sensor cable is positioned within the handle, and the distal end extends distally through the lumen of the delivery needle.

Abstract: An aid of a jet injector includes a first pinching piece and a second pinching piece that face each other, and pinches a skin in a state of holding the skin with pinching surfaces facing each other and thus forms a fold shape part where the skin is raised in a fold shape; and a reception portion that is provided in the first pinching piece, exposes a fold top part vicinity region, which is a region in a vicinity of a fold top part, in the fold shape part, and can receive the nozzle portion of the jet injector.

Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: A metering valve includes: a high-pressure partition wall to isolate a storage region from an atmospheric pressure space; an internal partition wall arranged inside the high-pressure partition wall and forming a metering chamber partitioned from the storage region; a stem linearly movably supported and biased to be positioned at an origin position; a first seal hole penetrating the high-pressure partition wall to extend over the atmospheric pressure space and the metering chamber with a first seal portion linearly movably supporting a first intermediate portion; a second seal hole penetrating the internal partition wall to extend over the metering chamber and the storage region with a second seal portion linearly movably supporting a second intermediate portion; and a starting-end-side stem internal flow path formed inside the stem and extending from a starting end of the stem to the second intermediate portion, the starting end being always positioned in the storage region.

Abstract: A sensing module for monitoring dosage delivery of a vaporized material, and a portable vaporization unit including the sensing module, include a light sensor that detects disruptions in a light path across a vapor channel, the disruptions caused by the vaporized material flowing through the vapor channel. The light sensor includes a UV light source, which may emit 370 nm wavelength light, and a UV light detector that converts intensity of incident light in the light path into a signal. A microprocessor of the sensing module compares the signal to a baseline measurement to determine the concentration of a medicament in the vapor; then, using the flow rate and activation time of the device, the microprocessor determines the dosage and can perform monitoring and reporting actions based on the dosage. A measuring circuit measures fluctuations in resistance/impedance of a vaporization element to further determine flow rate and/or dosage.

Abstract: A component of an electronic vapor provision device with a reservoir for storing source liquid, an atomizer for vaporizing source liquid from the reservoir and delivering vapor into an air flow path through the device, and an electrical power supply for providing electrical power to the atomizer comprises an absorbent element to collect source liquid escaped from the reservoir and located so as to be upstream of the atomizer with respect to an air flow direction along the air flow path when the component is assembled into the electronic vapor provision device.

Abstract: A ventilator including a housing having a front panel, and a rear panel opposite the front panel and configured to couple to the front panel, a receptacle coupled to the rear panel of the housing, the receptacle having a recess, a sealing element disposed within the recess, the sealing element having an inlet and an aperture, and a blower having a blower outlet and a blower inlet, the blower inlet coupled to the sealing element such that the blower inlet at least partially abuts the aperture. The receptacle and the sealing element may comprise an airflow pathway configured to allow for flow of air from the inlet of the sealing element into the blower inlet and out of the blower outlet.

Abstract: Disclosed herein is a console comprising: at least one air inlet; a first receptacle configured to host a first source of nitric oxide; a second receptacle configured to host a second source of nitric oxide; a controller configured to selectively couple the at least one air inlet to one of the first receptacle or the second receptacle to deliver the nitric oxide from the first or the second source; and an outlet coupled to the first and/or second receptacle and configured to deliver nitric oxide to a subject.

Abstract: An endotracheal tube assembly comprising a tubing body and a tubing adapter. The tubing body has proximal and distal ends and a lumen extending therebetween. The tubing adapter comprises an adapter body and a valve member. The adapter body has first and second connector portions defining first and second connector flow passages, respectively. The adapter body further defines a valve chamber in fluid communication with the first and second connector flow passages. The first connector portion is matingly engaged with the proximal end of the tubing body. The valve member has a flow passage extending therethrough, is positioned in the valve chamber, and is movable between an open position, wherein the flow passage is aligned with the first and second connector flow passages, and a closed position, wherein the flow passage is misaligned with the first and second connector flow passages.

Abstract: A cuffed tracheal tube has a shaft (10) with an inner component (30) having an inflation lumen (23) extending along a rib (33) along the outside of the component. The rib (33) terminates a short distance rearwardly of the patient end (14) of the inner component. The inflation lumen (23) is closed by an outer layer (51) applied over the inner component (30) and covering the patient end of the rib. Two closely spaced openings (54) through the rib (33) are spaced in the inflatable region of a silicone sealing cuff (13) secured around the patient end of the shaft.

Abstract: A system and method to match an interface to the face of a user for respiratory therapy. A facial image of the user is stored. Facial features based on the facial image are determined. A database stores facial profiles based on facial features and a corresponding plurality of interfaces. A database stores operational data of respiratory therapy devices with the plurality of corresponding interfaces. A selection engine is coupled to the databases. The selection engine is operative to select an interface for the user from the plurality of corresponding interfaces based on a desired outcome based on the stored operational data and the facial features. The collected data may also be employed to determine whether the selected interface is correctly fitted to the face of the user.

Abstract: An apparatus adapted for use in medical respiratory treatments utilizing a nebulizer mask. The apparatus includes an outer shell configured to fit over a nebulizer mask and collect the exhalant from the nebulizer into a suction device to prevent contamination of the surrounding environment.

Abstract: Systems and methods for model-driven system integration on a ventilator comprise a modeled exhalation flow. Ventilator flow sensors contain components that are easily damaged or impacted and have high rates of failure. Knowledge failure frequency and type may help determine when to replace, clean, or calibrate a flow sensor. A modeled exhalation flow may be trained for a ventilator. Additionally, the modeled exhalation flow may be compared to a flow sensor flow to determine a specific failure. Additionally or alternatively, the modeled exhalation flow may supplement, weight, or replace a faulty flow sensor measurement. These systems and methods may assist in identifying an inaccurate flow sensor measurement and/or providing a more accurate modeled flow estimate, thus increasing accuracy in patient-ventilator interactions.

Abstract: Provided are an oxygen concentrator, a control method, and a control program capable of preventing a drop in pilot pressure supplied to a pilot type solenoid valve used in at least either of the supply flow path opening/closing unit or the exhaust flow path opening/closing unit. An oxygen concentrator capable of preventing a pressure drop in both cylinders in the pressure equalization step and, as a result, preventing a drop in pilot pressure supplied to a pilot type solenoid valve used in at least either of the supply flow path opening/closing unit or the exhaust flow path opening/closing unit, as well as a pressure drop in the adsorption cylinder, by starting pressurization in advance in the already depressurized adsorption cylinder before the pressure equalization step.

Abstract: A chamber adaptor and a manufacturing method thereof. The chamber adaptor includes: a housing provided with a gas inlet, a gas outlet, a chamber inlet, and a chamber outlet, where the gas inlet is configured to be removably connected to a main board device, the gas outlet is configured to be removably connected to a respiratory pathway, the chamber inlet is configured to be removably connected to an input end of a chamber for storing liquid and the chamber outlet is configured to be removably connected to an output end of the chamber, the chamber adaptor further includes a control circuit and at least one sensing apparatus, where the at least one sensing apparatus is arranged on one end of the control circuit closer to the gas outlet and extends into a gas output channel.

Abstract: Disclosed herein is a system for delivering a nitric oxide to a subject, wherein the system comprises: (a) a nitric oxide injection line configured to inject a first gas at an injection point into a breathing conduit comprising a breathing gas, wherein the first gas comprises a first amount of nitric oxide; (b) a sampling line configured to sample a second gas comprising a second amount of nitric oxide and the breathing gas at a sampling location between the injection point of the first gas and a subject and (c) a feedback-loop controller that is in communication with: (i) a nitric oxide set-point controller configured to set a nitric oxide set-point amount; (ii) a source configured to provide a third gas having a third amount of nitric oxide; and (iii) at least one sensor configured to measure the second amount of nitric oxide in the sampling line.

Abstract: Proposed is a ventilator medication injection structure. The structure includes a T-tube (10) which has a tube body that extends from an inlet (11) to an outlet (12) and which has a branch tube (13), a cover (20) having a first tube body (22) formed below a flange (21), the cover (20) having a second tube body (23) and a male screw (24), and includes a packing closure (30) having a third tube body (32), a fourth tube body (33), a female screw (34), and a packing (36) which has elasticity and which is disposed inside the body (31). The first tube body (22) is fitted and assembled to the branch tube (13), and medication is capable of being injected inside the T-tube (10) with a syringe by piercing the packing (36) with a syringe needle and passing the syringe needle through the third tube body (32).

Abstract: Disclosed are methods, systems, and devices for providing a personalized humidification level. A control system receives, from a first sensor, one or more environmental parameters regarding conditions of the environment. The control system receives, from a second sensor, one or more physiological parameters associated with a user within the environment. The control system determines an action associated with a desired change in the humidity within the environment based, at least in part, on the one or more environmental parameters and the one or more physiological parameters. The control system causes, at least in part, a performance of the action associated with the change in the humidity in the environment based, at least in part, on moisture outputted by a humidifier module. The methods and devices perform the same functionality as the control system.

Abstract: A device (102) provides respiratory treatment for SDB (including mild OSA) and other respiratory conditions. A flow generator warms and humidifies gas at controlled flow levels. For example, the device (102) delivers breathable gas to the upper airway at flow rates of about 10-35 Liters/minute. Levels of flow rate, temperature and/or humidification of the device may be automatically adjusted in response to the detection of SDB events. The device may also automatically deliver adjustments of any of the levels in accordance with detected phases of respiratory cycles. In some embodiments, the device automatically delivers distinct levels to either of the nares based on independent control of flow to each nare. A warm-up procedure controls temperature and humidity at a desired target during a ramp-up of flow to the set therapy level. A cool-down procedure controls temperature above the dewpoint to avoid condensation internal to the device and patient interface.

Abstract: A respiratory or surgical humidifier comprising a heater base and an electrical connector. The heater base is configured to receive a humidifier chamber and supply humidified gases to a breathing tube when coupled with the chamber. The heater base also comprises a control circuit. The electrical connector is provided for electrically coupling the control circuit to a breathing tube. The electrical connector comprises a first power line, a second power line, and a data line configured to allow serial communication between the control circuit and one or more digital devices. Also provided is a humidifier system, a breathing tube, a humidifier chamber and an electrical connector for a humidifier.

Abstract: A valve cassette for a turbine mechanical ventilator includes a plurality of diaphragm check valves, a plate including a plurality of seats configured for receiving said plurality of diaphragm check valves, and at least one connecting element configured for fixing valve cassette to a turbine housing inlet. Each of said plurality of diaphragm check valves includes a flexible membrane and a plug. Each of said plurality of seats includes a bore for receiving said plug and a plurality of openings through which air is configured to flow through the valve cassette.

Abstract: A system and method for brainwave entrainment using virtual objects, in which brainwave entrainment is applied using some combination of gaming elements, brainwave is enhanced by virtue of the user's active participation, and long-term use is encouraged by virtue of the entertaining nature of the gamification. Depending on configuration, the system and method may comprise a display comprising virtual objects, a light-producing device (other than the display), an audio-producing device such as speakers or headphones, a haptic feedback device such as a vibratory motor, a device for monitoring the user's attention, and a software application which applies brainwave entrainment using some combination of the display, the light-producing device, the audio-producing device, and the haptic feedback device.

Abstract: A handheld electronic device is actuated by a user to energize selected colored lights and vibrations according to predetermined intensities and patterns that are associated with predetermined breathing patterns. The handheld electronic device uses multiple haptic inputs that engage associated sensory receptors of a person, namely, visual sensations, vibration sensations, and smell, a.k.a. aroma therapy.

Abstract: Methods and devices described for improved dynamic walled tubing and catheters.

Abstract: A vascular treatment device for use in a vessel includes a catheter and a microvalve occluder. The occluder includes braided elastic strands, each with a proximal portion, a central portion, and a distal portion, that are fixed to the outer surface of the catheter. The elastic strands. In an embodiment, the distal portions are attached circumferentially about an outer surface of the catheter at a location toward the distal end of the catheter, the central portions extend proximal and radially outward from the distal end, and the proximal portions of the strands are inverted back radially within the central portions are and coupled circumferentially about the outer surface of the catheter at a location proximally displaced from the distal portions. The proximal portion of the microvalve is coated in a fluid-impermeable membrane, and the distal portions of the strands are substantially uncoated.

Abstract: An introducer tube/stylet needle assembly provides for an interfacial channel between the stylet and introducer tube to allowing the flow of anesthetic through the introducer tube from a syringe or the like without removal of the stylet from an introducer tube. A valve structure may automatically block gas flow through the introducer tube when the stylet is removed.

Abstract: An endovascular management and tracking system comprises a track and at least one shuttle to which at least one elongate medical device can be respectively affixed. Each of the shuttle(s) is configured for being mechanically coupled to the track. Each of the shuttle(s) comprises a sled configured for riding on the track, an axial drive mechanism carried by the sled and configured for being actuated to axially translate the respective shuttle along the track, and a first actuator carried by the sled and configured for actuating the axial drive mechanism.

Abstract: A catheter system and method of introducing an intravenous catheter into a patient includes a syringe, an access needle, a pliable catheter, and a guidewire. The syringe has a first chamber and a distal syringe end portion, which defines a conduit distally extending to a distal syringe opening such that the conduit fluidly connects the first chamber to the distal syringe opening. The access needle defines a needle lumen longitudinally extending therethrough and is secured relative to the distal syringe end portion. The pliable catheter is releasably secured relative to the access needle. The guidewire distally extends through the conduit toward the distal syringe opening and is configured to selectively move through the conduit, the distal syringe opening, and along the needle lumen to thereby guide movement of the pliable catheter relative to the access needle for introducing the pliable catheter into the patient.

Abstract: An introducer includes an introducer hub and a vasodilating drug-delivery introducer sheath coupled to the hub and extending distally therefrom. The introducer sheath may include a primary lumen and infusion lumens for delivering a therapeutic agent such as a vasodilator through ports in the introducer sheath or may include an outer porous layer for the therapeutic agent to be delivered to the vessel, or may include at least one drug-coated outer layer for the therapeutic agent to be released from the drug-coated outer layer.

Abstract: Medical devices including a balloon and methods of making medical devices including a balloon are provided. The medical device includes a tubular element, a balloon, and a barrier between the tubular element and the balloon. When air is pushed into one end of the medical device, the balloon may be inflated. The method includes applying a barrier to a tubular element, applying an elastomer solution to the barrier and at least a part of the tubular element to form a coating, and curing the coating to form the balloon.

Abstract: A catheter having a head with a head orifice and a head channel connected to the head orifice, a primary lumen wall that defines an internal primary lumen volume, an adjustable neck that connects the head channel to the internal primary lumen volume, an adjustment system partially enclosed in the primary lumen wall that provides an articulation of the adjustable neck between an extended position to a contracted positon, wherein the articulation from the extended position to the contracted position provides a flexible tip catheter while the articulation from the contracted position to the extended position provides an ability to angulate toward a target.

Abstract: A ureteral stent and a manufacturing method of a ureteral stent are applied to the technical field of medical instruments, to effectively reduce ureteral stent failure in fluid guiding. The ureteral stent comprises an inner structure (200), and an outer structure (100) sleeved on the inner structure (200), wherein the outer structure (100) is a tube-shaped structure, and the outer structure (100) is made from a first wire (110). The ureteral stent can effectively reduce ureteral stent failure in fluid guiding.

Abstract: A dilator includes a tube including a proximal end, a distal end, and a central lumen therethrough. The proximal end includes a connector configured to connect to an inflation device. The dilator includes a balloon disposed between the proximal end and the distal end. The balloon is configured to transition between a contracted state and an expanded state, wherein the device is insertable into a body passage of a subject in need thereof.

Abstract: An apparatus includes a base housing, an actuator, and a blade. The base housing defines an upwardly presented support surface. The base housing also defines a distally oriented tip receiving recess. The distally oriented tip receiving recess is sized and configured to receive a bulbous distal tip of a dilation catheter. The actuator is movably coupled with the base housing. The blade us secured to the actuator. The actuator is operable to move the blade downwardly relative to the base housing. The blade is configured to sever a portion of a dilation catheter along a plane longitudinally interposed between the support surface and the tip receiving recess to thereby sever the bulbous distal tip of the dilation catheter in response to movement of the actuator relative to the base housing.