Abstract: The invention generally relates to systems and methods for improving sleep by treating at least one of rhinitis, congestion, and/or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, nasal congestion, coughing, sneezing, and nasal or throat irritation and itching.

Abstract: The invention generally relates to systems and methods for improving sleep by treating at least one of rhinitis, congestion, and/or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, nasal congestion, coughing, sneezing, and nasal or throat irritation and itching.

Abstract: Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

Abstract: Systems and methods for automatic detection of phrenic nerve stimulation are disclosed. A plurality of pacing pulses are delivered between an associated pair of electrodes of a plurality of electrodes. For each of the plurality of pacing pulses, a corresponding diaphragm movement during delivery of the pacing pulse is measured. For each of the plurality of pacing pulses, it is determined, based on the corresponding measured diaphragm movement, whether the pacing pulse results in phrenic nerve capture. For each pacing pulse that results in phrenic nerve capture, the pair of electrodes associated with that pacing pulse is recorded.

Abstract: An electrosurgical instrument having a microwave ablation antenna dimensioned to be suitable for insertion into a pancreas via a surgical scoping device, to provide a rapid and accurate alternative to known RF ablation techniques. The electrosurgical instrument comprises: a proximal coaxial transmission line for conveying microwave electromagnetic (EM) energy; a distal radiating portion; and an intermediate impedance transformer arranged to match an impedance of the coaxial transmission line to an impedance of the distal radiating portion, wherein the distal radiating portion comprises a microwave antenna for emitting the microwave EM energy conveyed by the coaxial transmission line, wherein the distal radiating portion has a maximum outer diameter less than an outer diameter of the coaxial transmission line. With these features, the instrument is able to deliver microwave energy via a small diameter structure.

Abstract: A microwave ablation catheter assembly is provided. A coaxial cable configured to connect to a microwave energy source at its proximal end and at its distal end to a distal radiating section. The coaxial cable includes inner and outer conductors and a dielectric positioned therebetween. An extended working channel is configured to receive the coaxial cable for positioning the coaxial cable adjacent target tissue. At least a portion of an inner surface of the extended working channel is electrically conductive. The electrically conductive inner surface of the extended working channel may function as a balun to maintain a balanced signal between the inner and outer conductors of the coaxial cable when the distal radiating section of the coaxial cable is energized.

Abstract: Articles of manufacture, including terminations of or attachments to optical fibers are configured to substantially prevent axial emission and redirect radially most if not all light emanating from optical fibers. In that, a termination may include a fiber cap of a unitary construction of a tube and an optical element disposed to face a sealed end of the tube and dividing a hollow of the tube and having a conical surface, or an optical element dividing the hollow and complemented by a cone. An example of termination includes an optical fiber element having an up-tapered end with a maximum taper-diameter exceeding the core-diameter and ending at a conical element with an apex angle from about 70° to about 100°. Articles of manufacture additionally including mounting contraptions cooperating such terminations with cannulae to form an attachment to a laser system. Methods for transmitting light through such articles of manufacture.

Abstract: A system and method for evaluating percutaneous needle pathways provides an automatic segmentation of local tissue structures and performs a weighting to rank a large number of paths to quickly identify clinically favorable choices.

Abstract: In some examples, patient-specific data can be received for a patient's joint. A virtual model of at least part of the patient's joint and associated musculature can be constructed based at least partially on the patient specific data and an implant configuration. A post-operative muscle moment capacity for the patient's joint can be calculated based at least partially on the virtual model. Muscle moment capacity curves and their use to estimate post-operative function are also disclosed.

Abstract: Systems and methods for modeling and planning a dental implant procedure are provided. A method for modeling and planning a dental implant procedure can include receiving a patient profile comprising a maxilla or mandible model of the patient and kinematic data associated with the movement of a jaw of the patient, identifying one or more candidate sites for dental implants, generating one or more dental implant parameters, determining an indication of a functional cone, determining one or more dental implant contact points, generating a constraint map, selecting an implant model, and generating a modified model.

Abstract: Methods and systems for intraoperatively determining alignment parameters of a spine during a spinal surgical procedure are disclosed herein. In some embodiments, a method of intraoperatively determining an alignment parameter of a spine during a surgical procedure includes receiving initial image data of the spine including multiple vertebrae and identifying a geometric feature associated with each vertebra in the initial image data. The geometric features each have a pose in the initial image data and characterize a three-dimensional (3D) shape of the associated vertebra. The method further comprises receiving intraoperative image data of the spine and registering the initial image data to the intraoperative image data. The method can then update the pose of each geometric feature based on the registration and the intraoperative image data, and determine the alignment parameter based on the updated poses of the geometric features associated with two or more of the vertebrae.

Abstract: A tool driver for a robotic system can include a sensor to allow the surgical robotic system to determine if a tool or a sterile adapter are fully coupled to the tool driver. The tool driver can include a rotating output that can manipulate a tool and translate perpendicular to a surface of a tool driver body. The tool driver can include a drive mechanism to rotate the rotating output.

Abstract: A system can include a magnetic resonance imaging (MRI) scanner and a surgical robot. The MRI scanner can include a permanent magnet array define a dome to surround an imaging region, or region of interest. The MRI scanner can be configured to generate an image of an anatomical structure (e.g. the head of a patient) positioned within the dome and imaging region thereof. The MRI scanner can include an opening for accessing the head of the patient. The surgical robot can include robotic arm. The surgical robot can be mounted to the MRI scanner. The surgical robot can be configured to pass through the opening to perform a surgical procedure on the patient.

Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.

Abstract: A medical device position notification system including a medical device and at least one sensor associated with the medical device, a processor, and a display device. The medical device is configured to be inserted into an orifice of the patient. The sensor measures information related to the position of the medical device in the patient's body, and communicates the information with the processor in real-time. The display device is coupled to the processor and is configured to display a tracing path of the position of the medical device in real-time. The display device is further configured to display a notification of the position of the medical device within the patient's body, such as a notification alert that the medical device has deviated from a predetermined path.

Abstract: A method comprises receiving a set of model points of a model of one or more passageways of a patient. The method further comprises receiving a set of measured points collected from within the one or more passageways of the patient. Each point comprises coordinates within a medical environment occupied by the patient. The method further comprises matching each measured point to a model point to generate a set of matches. The method further comprises assigning a weight to each of the measured points based on the set of matches to generate a weighted set of matches. The method further comprises moving the set of measured points relative to the set of model points based on the weighted set of matches.

Abstract: Methods and systems for performing a preliminary registration is provided. Image data corresponding to an image depicting a tracking device and an anatomical element may be received. Robot positional data corresponding to a position of a robot may also be received. The robot and the anatomical element may be located in a common three-dimensional coordinate system based on the image data and the positional data to yield a preliminary registration. A suggested robot position may be determined based on the preliminary registration and a dimensional reach of a robot arm of the robot.

Abstract: Systems, methods, and devices for generating a hybrid image are provided. A preoperative image may be received. A first intraoperative image may be received from an imaging device. The preoperative image and the first intraoperative image may be input into a hybrid model that combines the first intraoperative image with the preoperative image. A hybrid image comprising the preoperative image combined with the first intraoperative image may be generated with an output of the hybrid model.

Abstract: A robotic system includes a base, a support column, and a selective-compliance-articulated robot arm (SCARA) connected to the base via the support column. The SCARA is configured with ophthalmic visualization-specific kinematics. The SCARA includes first, second, and third revolute joints. A first link is connected to the base via the first revolute joint. A second link is connected to the first link via the second revolute joint, has a distal end connected to the third revolute joint, and is configured as a four-bar mechanism. The second link is connectable to a microscope. A linear actuator is connected to the second link. In response to electronic control signals from an electronic control unit, the linear actuator controls vertical motion of the SCARA. None of the revolute joints of the SCARA functions in an anti-gravity mode.

Abstract: Techniques for providing feedback during manual joint positioning include a computer-assisted device comprising an articulated structure comprising a joint and a brake associated with the joint and a control unit coupled to the articulated structure. To provide feedback during manual positioning of the joint due to manual force applied by an operator, the control unit is configured to determine a target position for the joint, determine kinematics of the joint relative to the target position, lock the joint when the joint is at the target position, release the brake when the kinematics of the joint indicate that the joint is moving towards the target position, and apply the brake when the kinematics of the joint indicate that the joint is moving away from the target position.

Abstract: Co-manipulation robotic systems are described herein that may be used for assisting with laparoscopic surgical procedures. The co-manipulation robotic systems allow a surgeon to use commercially-available surgical tools while providing benefits associated with surgical robotics. Advantageously, the surgical tools may be seamlessly coupled to the robot arms using a disposable coupler while the reusable portions of the robot arm remain in a sterile drape. Further, the co-manipulation robotic system may operate in multiple modes to enhance usability and safety, while allowing the surgeon to position the instrument directly with the instrument handle and further maintain the desired position of the instrument using the robot arm.

Abstract: A method is provided for a robotic endoscope system. The method comprises: generating a 3D depth map of an environment surrounding the robotic endoscope system; autonomously actuating a self-propelled base of a robotic support system to a desired location relative to a patient bed based on the 3D depth map, wherein the robotic support system comprises a robotic arm coupled to the self-propelled base at a proximal end and coupled to a flexible endoscope apparatus via an instrument driving mechanism (IDM) at a distal end; and actuating the robotic arm to align the IDM to a component coupled to or part of the patient bed.

Abstract: A medical remote control for wirelessly controlling a medical instrument or device includes a housing having a fastening portion to be fastened to an object, in particular the medical, digitally controllable instrument or device; an actuating button located in or on the housing, in particular exactly one single actuating button, for generating an input signal by manual actuation of the actuating button; a wireless data interface for establishing a wireless data connection to an external data interface, in particular a data interface of the medical instrument or device, and for transmitting data; and a control unit for processing the input signal of the actuating button and determining an associated control signal based on the input signal and to transmit the control signal via the data interface. The medical remote control can be used with or in a control system, a control method, and a computer-readable storage medium.

Abstract: A surgical navigation system and method of operating the same involve a pointer tool and a localizer configured to track the pointer tool. Controller(s) is/are coupled to the localizer and are configured to generate a virtual boundary relative to a bone at a surgical site. The virtual boundary has a shape that delineates a region of the bone to be removed from a region to be avoided. The controller(s) identify, with the localizer, a position of one or more landmarks at the surgical site in response to the pointer tool touching the one or more landmarks at the surgical site. The controller(s) revise the shape of the virtual boundary based on the position of the one or more landmarks.

Abstract: A device for clearing obstructions from a medical tube includes a housing defining an interior, an exterior, and a port providing fluid communication therebetween. The device further includes an elongated guide wire residing at least partially within the housing, and first and second rollers defining a nip therebetween that are located within the housing. A guide wire extends through the nip and is drivable for advancement and retraction thereof through the port via rotation of the rollers.

Abstract: The applicator tip for root canal sealer is used to coat walls of a root canal with root canal sealer prior to filling the root canal with a filler material. The applicator tip is formed from a hollow shell having a connection portion and an application portion. The connection portion is adapted for connection to a supply of root canal sealer, such as a source of pressurized adhesive cement or the like. The application portion has a proximal end and a distal end, a diameter of the application portion continuously decreasing from the proximal end to the distal end. A plurality of recesses are defined in an outer surface of the application portion of the hollow shell, and a plurality of radially spaced frustoconical openings extend through the application portion of the hollow shell, such that each of the openings is centrally located within a corresponding one of the recesses.

Abstract: Apparatuses (e.g., systems) and methods for quickly and accurately determining tooth axis information associated with a subject's dental data. A stage of a prior treatment plan that most closely matches to a digital model of a subject's current dentition may be used to approximate tooth axis information for the subject's current dentition.

Abstract: Apparatuses (e.g., systems) and methods for quickly and accurately determining tooth number information associated with a subject's dental data. A stage of a prior treatment plan that most closely matches to a digital model of a subject's current dentition may be used to approximate tooth numbering for the subject's current dentition.

Abstract: In an embodiment, a method of manufacturing customized ceramic labial/lingual orthodontic brackets by additive manufacturing may comprise measuring dentition data of a profile of teeth of a patient, based on the dentition data, creating a three dimensional computer-assisted design (3D CAD) model of the patient's teeth, and saving the 3D CAD model, designing a virtual 3D CAD bracket structure model for a single labial or lingual bracket structure based upon said 3D CAD model, importing data related to the 3D CAD bracket structure model into an additive manufacturing machine, and directly producing the bracket with the additive manufacturing machine by layer manufacturing from an inorganic material including at least one of a ceramic, a polymer-derived ceramic, and a polymer-derived metal.

Abstract: One aspect of the present application provides a computer-implemented method of generating designs of shell-shaped tooth repositioners, the method comprising: obtaining an orthodontic treatment plan comprising a series of successive repositioning steps whose repositioning targets are successive tooth arrangements including a first intermediate tooth arrangement, . . .

Abstract: An accurate and precise surgical guide for dental procedures, especially a procedure involving a subject with few or no teeth as well as methods for making and use of such guides.

Abstract: Provided herein are systems and methods for automatically segmenting a 3D model of a patient's teeth. A patient's dentition may be scanned. The scan data may be converted into a 3D model, including a sparse voxel representation of the 3D model. Features can be extracted from the sparse voxel representation of the 3D model and input into a machine learning model to train the machine learning model to segment the 3D model into individual dental components.

Abstract: A scanning system for generating a three-dimensional (3D) representation of an object includes: an intraoral scanning device including one or more projector units configured to project a pattern on a surface of the object; two or more camera units configured to acquire a set of images including at least one image from each camera unit, wherein each image is composed of an array of pixels, wherein each pixel includes a pixel color defined by one or more color channels; wherein the scanning system further includes one or more processors configured for: determining points in three-dimensional (3D) space that form a solution to a correspondence problem associated with the set of images, wherein the points are determined by comparing pixel colors with computed colors associated with camera rays corresponding to each pixel; and generating the three-dimensional (3D) representation based on the determined 3D points.

Abstract: A device and methodology for flossing teeth. The device includes a body having a first arm and a second arm. The first and second arms connect at a vertex. The first and second arms extend distally from the vertex and cross over each other at a crossing over region, so that transverse movement of the first arm relative to the second arm between the vertex and the crossing over region causes an opposite transverse movement at distal ends of the first arm and the second arm. A length of dental floss is coupled between the distal ends of the first arm and the second arm at first and second attachment positions. When in a neutral position with no forces applied to the first arm and the second arm, the distance between the first and second attachment positions is smaller, and the dental floss looser, relative to when the first and second arms are squeezed together between the vertex and crossing over region such that distance between the first and second attachment positions is larger, and the dental floss tauter.

Abstract: A dental flosser that includes a U-shaped portion having a first arm and a second arm spaced apart from each other, a handle portion and a floss strand. The first arm includes an outer surface, an inner surface and first and second opposing side surfaces. The first arm defines a first arm width between the inner and outer surfaces. The second arm includes an outer surface, an inner surface and first and second opposing side surfaces. The second arm defines a second arm width between the inner and outer surfaces. A first inner portion of the floss strand extends through the inner surface of the first arm and toward the outer surface of the first arm. The first inner portion has a first length and is exposed through at least one of the first and second opposing side surfaces of the first arm along a portion of the first length.

Abstract: Disclosed is an oral irrigator easily disassembled and assembled, and the oral irrigator includes: an oral irrigator nozzle, an oral irrigator upper cover, an oral irrigator inner shell, an oral irrigator main shell and an oral irrigator bottom cover. One end of the oral irrigator main shell is provided with the oral irrigator inner shell and the oral irrigator upper cover in sequence, and the other end of the oral irrigator main shell is detachably connected to the oral irrigator bottom cover. The oral irrigator main shell is provided with a first accommodating cavity and a second accommodating cavity in sequence, and the first accommodating cavity and the second accommodating cavity are separated by a charging base; a water pump mechanism is provided in the first accommodating cavity, and the second accommodating cavity is configured to store water. The oral irrigator inner shell is provided with a locking assembly.

Abstract: An oral cavity suction device comprising a vacuum hose and a vacuum tip including a tube body having a base end and a distal end that is a suction opening. The oral cavity suction device includes a hose-side light-outputting end face in the vacuum hose arranged to face the distal end side of the vacuum hose to output light input from a light source. The oral cavity suction device includes a light guiding element in the vacuum tip, with a tip-side light-receiving end face arranged to face the base end side of the vacuum tip to guide light input from the tip-side light-receiving end face and project the light. The hose-side light-outputting end face and the tip-side light-receiving end face allow light to be transmitted in a state in which the vacuum tip is completely connected to the vacuum hose.

Abstract: A wear-out assessment for an oral care system (14) (e.g. an oral cleaning device) is disclosed. A sensor unit (16) of the oral care system is adapted to provide a sensor signal related to a cleaning efficacy of a cleaning function of the oral care system when generated when the oral care system is inside a user's mouth. The sensor unit (16) may be, or may be coupled to, a component which is used during execution of an oral care function of the device, for example a sensor for detecting cleaning progress in the mouth, or a component which drives a cleaning or treatment action in the mouth. In accordance with the invention, the sensor signal (20) generated when the oral care system is outside the mouth is used for performing a wear-out assessment. As relevant components used by the oral care system (14) for the oral care function wear, characteristics of the sensor signal (20) may change in a predictable way, which can be used to identify when a wear-out state has been reached.

Abstract: In a device that includes a vibrating mouthpiece, a source of vibratory movement is connected to a relatively large, relatively stationary mass, or anchor, so the equal and opposite vibrational momentum of the handpiece (plus large mass) results in very little vibrational amplitude of the handpiece-plus-mass, while the active mouthpiece has high vibrational amplitude. In an example, a mouthpiece which engages with a part of a dental arch, is actively cleaning, while a block on the other side of the dental arch acts to anchor the vibration source to the much larger mass of the user's jaw (and head). When the user's jaws grip the block, there will be very little vibration of the handpiece or the user's teeth-jaw-head mass and consequently, the mouthpiece will vibrate at a greater amplitude than it would without the anchor. This leads to greater efficiency of the device.

Abstract: A pouch for placement in an oral vestibule of a human for absorption of an active ingredient includes a pouch sleeve comprised of a material which is permeable to saliva, an active ingredient composition including caffeine and taurine, and an imprint positioned on an exterior surface of the pouch sleeve. The imprint, the permeability of the material of the pouch sleeve, and the active ingredient composition are configured such that, because of an effect of the saliva, the imprint is gradually released from the exterior surface of the pouch due to contact with the saliva. The saliva extracts the active ingredient composition from the pouch and fades the imprint so the imprint is no longer visually perceptible just when the active ingredient composition is substantially or completely extracted from the pouch. The imprint acts as a visual indicator of a consumption status of the active ingredient.

Abstract: The present disclosure provides a device for measuring a stability of an implant system. The device includes a housing configured to be positioned adjacent the implant system. The device also includes an actuator coupled to the housing. The actuator is configured to vibrate the implant system when actuated. The device also includes a motion sensor coupled to the housing, and a controller in communication with the motion sensor and the actuator. The controller includes at least one processor, and data storage including program instructions stored thereon that when executed by the at least one processor, cause the controller to perform functions including: (i) receiving motion data from the motion sensor when the actuator is actuated, and (ii) determining an angular stiffness of the implant system based on the motion data.

Abstract: Indwelling body lumen expanders which allow for the maintenance and patency of a body lumen, such as the prostatic urethra to relieve urethral obstruction, are described. Because the one or more expanders are configured to be relatively larger in diameter than the diameter of the body lumen, the expanders may become invaginated into the lumen wall thus enabling the prostheses to avoid fluid exposure which in turn prevent the prostheses from becoming encrusted or calcified.

Abstract: Described herein are methods for lengthening tubular organs using expandable implants. The expandable implants may be secured along a length of a tubular organ by forming a plication at each end of the implant. Securing the expandable implants in this manner may be used to treat short bowel syndrome. Methods for selecting and implanting an expandable implant suitable for lengthening a tubular organ according to predetermined patient parameters are further described herein.

Abstract: Implantable medical devices have zones of high in vivo stability that are adjacent to zones of relatively low in vivo stability, so that when these medical devices are implanted into a host, the zones of low in vivo stability degrade first and allow the formation of independent segments of relatively intact high in vivo stability bands that are sufficiently small that they may pass from the host in a non-harmful manner.

Abstract: A tubular electrospun graft implant is provided distinguishing an electrospun tubular layer which has a longitudinal axis and an outer surface. Polymer layers of an electrospun sheet have been rolled over the outer surface of the electrospun tubular layer and around the longitudinal axis of the electrospun tubular layer. A polymer layer electrospun is further distinguished over the rolled polymer layers of the electrospun sheet. Also provided is a tubular graft implant having layers of an electrospun polymer sheet rolled around a longitudinal axis defining the inner diameter of the tubular graft implant. These layers of the electrospun polymer sheet are moving independent from each other when the tubular graft implant is bending. Compared to regular spun graft, higher burst pressure is achieved, and crushing zones have been created between the layers to reduce the bending stiffness and facilitate bending with superior kink resistance.

Abstract: A hybrid endoprosthetic device comprises a stented tubular part and a branched tubular body connected such that a main lumen of the stented tubular part communicates with a main lumen of the branched tubular body. The branched tubular body has multiple branch lumens for connection with natural vessels of the vasculature, and includes at least one branch lumen for access to facilitate delivery and implantation of the hybrid endoprosthetic device by an endovascular step in a hybrid surgical procedure. The hybrid endoprosthetic device is configured to replace a part of the aorta and common iliac artery. A delivery system for use with the device is also disclosed.

Abstract: An artificial muscle including a housing, an electrode pair positioned in an electrode region of the housing, the electrode pair including a first electrode and a second electrode, the first electrode and the second electrode each including a pair of tapered tab portions and a bridge portion, the tapered tab portions each having a first end proximate to the expandable fluid region and an opposite second end proximate the electrode region, each of the second ends tapering in a direction opposite the expandable fluid region, the pair of tapered tab portions extending parallel to one another to define a gap portion between the pair of tapered tab portions, the bridge portion interconnecting the pair of tapered tab portions, and a dielectric fluid housed within the housing, wherein the electrode pair is actuatable between a non-actuated state and an actuated state such that actuation from the non-actuated state to the actuated state directs the dielectric fluid into an expandable fluid region of the housing.

Abstract: Self-deploying devices, systems, and methods of use to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more surgical implants that include a sheet of biocompatible or bioabsorbable material that can be positioned as an implant within a patient's body, the sheet of material being introduced into the patient's body in a mechanically compressed or folded or rolled form. The sheet of material can include a self-expanding ring or framework that resiliently biases the sheet of material to open into a flat sheet once mechanically released within the patient's body. The sheet of material can be used for performing a surgical repair by attaching the deployed sheet to tissue within the body. The surgical repair can comprise an orthopedic repair or a muscular repair. In some examples, the self-expanding ring or framework is removable after the sheet of material is implanted.

Abstract: Absorbable implants can be used to reconstruct the nipple with regenerated tissue resulting in improved aesthetic satisfaction. The implants are particularly suitable for use in plastic surgery procedures, for example, to reconstruct the nipple following total mastectomy and breast reconstruction. The implants may be formed from absorbable mesh and/or dry spun sheet.

Abstract: A prosthesis for reconstruction and/or augmentation of an anatomical shape. The prosthesis may have a three-dimensional configuration to reconstruct and/or augment the anatomical shape of a human breast. The prosthesis may be configured to encourage ingrowth of fat and/or tissue to fill open spaces within and about the prosthesis. The prosthesis may employ a structure having a plurality of cavities to allow fat and/or tissue to fill and pass through the structure and fill-out the anatomical shape of the reconstructed and/or augmented breast. The prosthesis may include a hollow core which may be accessible from one or both ends of the prosthesis. The prosthesis may be fabricated using a plurality of segments and/or layers of material which can be arranged about the core and joined to create the desired shape for the prosthesis.