Patents Issued in October 17, 2024
  • Publication number: 20240342363
    Abstract: Provided is an electroosmotic pump including: a housing having a shaft hole; a shaft passing through the shaft hole, arranged to extend inside and outside the housing, and capable of a reciprocating motion in an extension direction thereof; and a moving member coupled to the shaft outside the housing. The shaft may be press-fittable into the moving member.
    Type: Application
    Filed: June 21, 2024
    Publication date: October 17, 2024
    Applicant: EOFLOW CO., LTD.
    Inventors: Do Kyung LEE, Jun Hyuk JEONG
  • Publication number: 20240342364
    Abstract: A drug delivery device includes a reservoir configured to receive a fluid, a cannula in fluid communication with the reservoir, with the cannula configured to be inserted into subcutaneous tissue or muscle tissue of a patient, and a pump configured to deliver a fluid from the reservoir to the cannula. The cannula includes a bioactive agent configured to cause a tissue response to decrease a pressure required to deliver fluid from the reservoir. The tissue response can include vasodilation, vasoconstriction, increased tissue permeability, increased flow of interstitial fluid or enzymatic deterioration of extracellular matrix.
    Type: Application
    Filed: August 12, 2022
    Publication date: October 17, 2024
    Inventors: Steve Beguin, Stuart Plascott, Ronald J. Pettis, Natasha G. Bolick, John Adams
  • Publication number: 20240342365
    Abstract: A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 17, 2024
    Inventors: David S. Gillett, Andres Dandler, Mark C. Estes, Kenneth C. Hsu
  • Publication number: 20240342366
    Abstract: The present invention relates to an implantable medical device comprising a device body having an internal reservoir configured to expand in size. The device can comprise an anchor structure affixed to a wall of the device body and having an interior passage, a conduit having a fill end and a device end with a conduit lumen extending therethrough, and a plug-port member comprising a shaft section opposite to a plug section, with a port section located therebetween. The device end of the conduit can be coupled to the shaft section and the plug-port member can be located within the interior passage such that in a fill configuration, the port section and the plug section are located within the internal reservoir allowing the fluid to pass from the conduit lumen into a shaft lumen, through one or more port openings in the port section and into the internal reservoir.
    Type: Application
    Filed: April 12, 2023
    Publication date: October 17, 2024
    Applicant: Allurion Technologies, Inc.
    Inventors: David W. NELSON, Bruce A. HORWITZ
  • Publication number: 20240342367
    Abstract: A medical device includes a drug reservoir located within a reservoir chamber of the device that includes a first side and a second side directly opposite the first side defining a reservoir volume there between. The device further includes a volume sensor system including a transmitter positioned to transmit a signal toward the second side and one or more sensors configured to receive the signal and indicate a current volume capacity of the drug reservoir.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 17, 2024
    Inventors: Erik J. Peterson, Touby A. Drew, Jerel K. Mueller, Sarah J. Offutt, Carl M. Feller
  • Publication number: 20240342368
    Abstract: A cassette for holding fluid path components for a fluid injector may include a body defining at least one feature for holding at least one fluid path component for the fluid injector; and a connecting member for removably connecting the body of the cassette to the fluid injector, the connecting member operatively connected to the body, wherein the connecting member comprises at least one pivotable connecting feature protruding from the body, and wherein each of the at least one pivotable connecting feature is configured for removably connecting to a corresponding connecting feature receiver on the fluid injector such that the body is pivotally movable relative to the fluid injector between a first, unlatched position and a second, latched position in which the at least one fluid path component on the body of the cassette is positioned for operative connection to a corresponding feature of the fluid injector.
    Type: Application
    Filed: June 27, 2024
    Publication date: October 17, 2024
    Inventors: Andrew Naples, Kevin Cowan, Michael Spohn, John Haury, Patrick Campbell, James Dedig, Randy Lee, John Caswell, Katherine MacNamee, James Tirone
  • Publication number: 20240342369
    Abstract: A roller clamp control mechanism which adapts to the roller clamp to control the position of the roller clamp and adjust the fluid flow rate in a connector tube of an infusion set is provided. The mechanism may include a roller clamp, a roller wheel, a control unit, rotating bearings, a body fixture, and a linear drive to control the position of the roller wheel on the connector tube. Different assemblies for the roller clamp control mechanism are shown and described, all of which allow for changing the clamping pressure on the connector tube using a control unit. Infusion sets and methods of adjusting fluid flow rates are also provided.
    Type: Application
    Filed: April 11, 2024
    Publication date: October 17, 2024
    Inventors: Jason Andrew WINE, Michael B. GOGARTY
  • Publication number: 20240342370
    Abstract: A valve connector for infusion medical lines includes a base and a lid defining an inlet and an outlet, and an internal elastic element having a head provided with a pre-slit and normally arranged in the inlet to close the connector in deactivated condition. The base is formed with a hollow pin having a closed terminal with a plurality of radial slots and the elastic element has an end retaining part formed with a convolute which—during the displacement of the elastic element towards an activated opening condition of the connector—deforms under traction within an annular space of the base.
    Type: Application
    Filed: April 11, 2024
    Publication date: October 17, 2024
    Applicant: Industrie Borla S.p.A.
    Inventor: Gianni GUALA
  • Publication number: 20240342371
    Abstract: An apparatus and method for delivering fluid from a syringe to a subject using a pumping device of a flow control apparatus. The method includes locating the flow control apparatus on a horizontal support surface. Providing the syringe with a volume of fluid including a total amount of preferred nutrient and an amount of non-preferred nutrient liquid. Mounting the syringe relative to the flow control apparatus whereby the syringe is oriented in a generally vertical orientation such that an outlet of the syringe faces upward. Initiating operation of the pumping device to draw the fluid from the syringe for a duration of time to preferentially deliver at least a portion of the total amount of preferred nutrient in the fluid to the subject.
    Type: Application
    Filed: June 27, 2024
    Publication date: October 17, 2024
    Inventors: Kenneth M. BREITWEISER, Kurt Schneider, Robert B. Gaines, Thomas G. Lewis, Emma C. Buckles, Michael C. Dorsey, Christopher A. Knauper, Ashanti Bryant, Meghan Fox, Jessica Watts Miller
  • Publication number: 20240342372
    Abstract: A fluid extravasation detection device detects the subcutaneous extravasation of fluid from a vein containing an intravenous (IV) catheter. The device includes one or more first temperature sensors for positioning on skin near an entry point of the IV catheter into the vein, and one or more second temperature sensors for positioning on skin near a tip of the subcutaneously located IV catheter. The first and second temperature sensors are operably connected to an electronic thermometer that compares the temperature difference between a first temperature and a second temperature. The first temperature is determined based on temperature detected by at least one of the one or more first temperature sensors. The second temperature is determined based on temperature detected by at least one of the one or more second temperature sensors. An alarm is activated if the difference between the first and second temperatures changes more than a predetermined amount.
    Type: Application
    Filed: April 9, 2024
    Publication date: October 17, 2024
    Inventors: Scott D. Augustine, Randall C. Arnold, Garrett J. Augustine
  • Publication number: 20240342373
    Abstract: It may desirable to monitor or control a pump remotely. For example, the pump may be positioned near the patient, with remote control or monitoring of the pump occurring in a control room. In one exemplary embodiment, the pump is used in an MRI environment. In another exemplary embodiment, the pump is used in a hyperbaric chamber. The pump may monitor one or more physiological parameters and transmit them to the remote. The pump may also transmit information relating to the pump's operation. The pump may send the device and/or physiological data using one or more packets. The packets may consist of low priority sequential packets and high-priority asynchronous packets. The high-priority packets may enable the real-time monitoring of a patient's heart beat or other physiological parameter.
    Type: Application
    Filed: June 26, 2024
    Publication date: October 17, 2024
    Inventor: Roger Susi
  • Publication number: 20240342374
    Abstract: A syringe adapter includes an outer housing having a sidewall defining an interior space, a membrane housing positioned within the interior space of the outer housing and moveable from a first position within the outer housing to a second position within the outer housing spaced from the first position, with the membrane housing receiving a membrane, a needle hub connected to the outer housing and configured to be connected to a syringe, with the needle hub rotatable relative to the outer housing, and a needle connected to the needle hub. The needle having a first end and a second end positioned opposite the first end, with the second end of the needle received within the membrane when membrane housing is in the first position. The needle is rotatable relative to the needle hub.
    Type: Application
    Filed: August 12, 2022
    Publication date: October 17, 2024
    Inventors: Tianqi Hang, Nicole Jean DiStefano, Balaji Sadasivam, Rafael Gonzalez Macias, Noel Antonio Medrano, Shivani Rajesh Patel
  • Publication number: 20240342375
    Abstract: Described is an actuation mechanism for a medicament delivery device having a needle with a distal tip. The actuation mechanism comprises an outer sleeve telescopically relative to the delivery device and an inner sleeve telescopically arranged relative to the outer sleeve. The outer sleeve is axially translatable relative to the delivery device, and the inner sleeve is axially translatable relative to the outer sleeve. In a first state, the inner sleeve protrudes distally from the outer sleeve and the outer sleeve protrudes distally from the delivery device. In a second state, the inner sleeve is contained within the outer sleeve. Movement of the outer sleeve proximally relative to the delivery device in the second state initiates delivery of a medicament in the delivery device.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 17, 2024
    Inventor: Stephan Riedel
  • Publication number: 20240342376
    Abstract: A slider of a medicament delivery device power pack, the slider comprising: a body extending along a longitudinal axis between a first end and a second end; and a straight guide surface extending from a wall of the body in a direction transverse to the longitudinal axis, and extending from a first end to a second end in a direction that is angled relative to both the longitudinal axis and to a plane transverse to the longitudinal axis.
    Type: Application
    Filed: August 3, 2022
    Publication date: October 17, 2024
    Inventors: Ming-Ting Yin, Philipp Zingel, Roman Käslin, Lino Manuel Heckhorn Ghilardi
  • Publication number: 20240342377
    Abstract: The invention provides methods and apparatus for injecting a medicine, especially a highly viscous medicine. Conventional methods and apparatus for injecting viscous medicines suffer from a variety of problems such as excessive force during the initial needle insertion and initial injection. In an inventive method, during the initial phase of the injection, energy is stored in a torsion spring that is subsequently released during a later stage of the injection. The present invention also provides for an improved autoinjector; especially via the use of a combination compression and torsion spring that powers the injection through controlling force applied to plunger via a screw flange or nut having pins that ride in a prescribed path down the length of the autoinjector.
    Type: Application
    Filed: April 2, 2024
    Publication date: October 17, 2024
    Inventors: William G. Atterbury, Douglas E. Boyd
  • Publication number: 20240342378
    Abstract: Disclosed is an auto-injection apparatus for receiving a syringe, including: an outer casing enclosing a drive assembly and a syringe carrier configured to hold a barrel of the syringe, the syringe carrier being forward of the drive assembly and having stowed and delivery positions; an interlock extending between the syringe carrier and a syringe carrier housing at least partially surrounding the syringe carrier, the interlock preventing forward motion of the syringe carrier under the influence of an insertion actuator whilst in the stowed position. The drive assembly includes the insertion actuator for inserting a needle of the syringe into an injection site and a delivery actuator for driving a plunger into a barrel of the syringe which contains a substance for injection. The syringe carrier includes an interlock release mechanism which is configured to release the interlock such that the insertion actuator drives the syringe carrier forward.
    Type: Application
    Filed: June 14, 2024
    Publication date: October 17, 2024
    Inventors: Matthew John Dobson, Oliver Gould, Andrew Hung, Tahir Shabudin, Matthew David Farmer, Kuiwei Zhang
  • Publication number: 20240342379
    Abstract: The present application provides a spark generator for generating pressure.
    Type: Application
    Filed: July 22, 2022
    Publication date: October 17, 2024
    Applicant: L'Oreal
    Inventors: Chin Kai Lee, Woo Ram Park
  • Publication number: 20240342380
    Abstract: A flush syringe for use in maintaining intravenous catheters, wherein the flush syringe can more efficiently and effectively flush the catheters by providing a pulsating, pulsatile, and/or pulsative flow of fluid that can be produced using momentum of the fluid moving. A steady force applied to a plunger while flushing can provide the pulsating, pulsatile, and/or pulsative flow of the fluid to the catheters.
    Type: Application
    Filed: April 8, 2024
    Publication date: October 17, 2024
    Applicant: Becton, Dickinson and Company
    Inventor: Bryan BIHLMAIER
  • Publication number: 20240342381
    Abstract: A medical syringe having a forwardly projecting needle that is selectively retractable following use and also having a specially configured plunger handle and thumb cap that cooperate to form a concave pressure application surface (“CPAS”). The concave pressure application surface at the rear of the plunger handle enables the subject medical syringe to achieve functional advantages, each with an associated therapeutic benefit, that are not achieved with use of the prior art devices.
    Type: Application
    Filed: June 21, 2024
    Publication date: October 17, 2024
    Inventors: Thomas J. Shaw, Hannah Monique Meyers
  • Publication number: 20240342382
    Abstract: A pen cap for a medication delivery pen includes a piston-style detector mechanism. The piston-style detector mechanism includes at least an inner shell having first open end through which the medication delivery pen can be inserted, a second end opposite the first end, a sidewall defined by an outer surface and an opposing inner surface, and a passageway extending from the outer surface to the inner surface. The sidewall extends between the first end and the second end thereby defining a pen-receiving cavity there between. The piston-style detector mechanism further includes at least one switch and a translatable shaft at least partially disposed in the passage. The translatable shaft includes a body that extends at least from a pen-interfacing portion in the pen-receiving cavity to a switch-interfacing portion thereof.
    Type: Application
    Filed: April 12, 2024
    Publication date: October 17, 2024
    Inventors: John LOVE, Adam Joseph LIVINGSTON, George CROTHALL, Jeffrey JOHNSON, Sarah MATARESE
  • Publication number: 20240342383
    Abstract: A plunger device for a drug delivery device is disclosed. The plunger device includes a plunger rod having a proximal end and a distal end configured to be attached to a stopper. The plunger device further includes at least one tracking element operatively connected to an outer surface of the plunger rod, the at least one tracking element extending along a longitudinal axis of the plunger rod. The plunger device also includes at least one power supply operatively connected to the at least one tracking element, and at least one current sensing device operatively connected to the at least one power supply and configured to detect an electrical contact established between the at least one tracking element and a conductive element external to the plunger rod.
    Type: Application
    Filed: February 28, 2024
    Publication date: October 17, 2024
    Inventors: Hervé Monchoix, Damien Maréchal
  • Publication number: 20240342384
    Abstract: In at least one embodiment, the drug delivery device comprises a mechanism unit (MU) with an electrical element and an arrangement for changing an operational state of the mechanism unit. The mechanism unit is configured to enable a dispense process for dispensing a drug. Furthermore, the mechanism unit is configured to be operatively coupled with a selected drug reservoir unit (RU) which, when coupled with the mechanism unit, interacts with the electrical element and thereby changes an electrical property of the electrical element in a characteristic manner. The mechanism unit is configured such that operation of the arrangement for changing the operational state of the mechanism unit is prevented unless the electrical property of the electrical element is changed in at least one characteristic manner.
    Type: Application
    Filed: November 1, 2022
    Publication date: October 17, 2024
    Inventors: Stefan Alt, Tim Glässer, Michael Helmer, Stephan Mücke, Peter Nober, Michael Schabbach, Martin Vitt
  • Publication number: 20240342385
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Application
    Filed: June 26, 2024
    Publication date: October 17, 2024
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Publication number: 20240342386
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Application
    Filed: June 27, 2024
    Publication date: October 17, 2024
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Publication number: 20240342387
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Application
    Filed: June 26, 2024
    Publication date: October 17, 2024
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Publication number: 20240342388
    Abstract: An interventional injection device includes an operating handle, a sheath and an injection member. The operating handle includes a housing and a driving assembly. The driving assembly includes a driving knob that is rotatably connected to the housing and a driving rod that is movably inserted into the housing and threaded to the driving knob. A proximal end of the sheath is fixedly connected to the housing. The injection member is movably inserted in the sheath. The injection member includes a first channel and an injection needle connected to a distal end of the first channel in a tight seal, and a proximal end of the injection member is fixedly connected to the driving rod. The driving rod is configured to move axially by rotation of the driving knob relative to the housing.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 17, 2024
    Inventors: Nan Shao, Yang Li, Zhenping Zhuang, Peng Zhu
  • Publication number: 20240342389
    Abstract: A therapeutic agent delivery device includes a disposable portion and a reusable portion that detachably carries the disposable portion. The reusable portion includes a drive mechanism having a guide, a rotary actuator, and a follower drivably coupled to the rotary actuator and movably coupled to the guide. The rotary actuator is actuatable to rotatably drive the follower, and the follower thereby follows the guide and translates the drive mechanism. The drive mechanism thereby translates a syringe assembly of the disposable portion from a stowed configuration to a deployed configuration.
    Type: Application
    Filed: August 19, 2022
    Publication date: October 17, 2024
    Inventors: William Godwin ATTERBURY, David Arthur HOLLEY, Michael Lewis MARSHALL, Kenneth Bryan SCOTT
  • Publication number: 20240342390
    Abstract: A device for holding a needle cap of a syringe is provided. The device includes holding means including at least two holding points for holding the needle cap. The holding means are configured for receiving the cap when inserted along a first direction, applying a cap holding force exceeding a release force required to release the cap from the syringe, and disengaging from the cap when the cap is displaced along the first direction. The device further includes an end stop configured for withstanding a cap applying force in the first direction. The device further includes fastening means for releasably fastening the device to an external surface with an attachment force exceeding the applied release force and the cap applying force.
    Type: Application
    Filed: April 17, 2024
    Publication date: October 17, 2024
    Inventors: Sabina Kjærgaard Sidelmann Nielsen, Dennis Kjærgaard Sidelmann Nielsen
  • Publication number: 20240342391
    Abstract: A needle shield remover for a wearable injector includes a first portion having a cam member, the first portion having a top surface and a bottom surface positioned opposite to the top surface, and a second portion connected to the first portion. The second portion having a top surface and a bottom surface positioned opposite to the top surface, with the second portion including a device connector configured to secure the second portion of the needle shield remover to the wearable injector. The first portion is moveable relative to the second portion between a first position where the cam member is aligned with the top surface of the second portion and a second position where the cam member protrude from the top surface of the second portion. The cam member is configured to contact a housing of the wearable injector when the first portion is in the second position.
    Type: Application
    Filed: April 17, 2023
    Publication date: October 17, 2024
    Inventor: Matthew C. Klimash
  • Publication number: 20240342392
    Abstract: The present disclosure provides a needle cutting device for cutting an injector needle. The needle cutting device includes a housing extending along a longitudinal axis between a first open end and a second end. The needle cutting device also includes a cutter assembly aligned with the housing along the longitudinal axis, wherein the cutter assembly comprises a blade and a cutter body. The housing comprises a wall that defines a cavity, the cavity extending between the first open end of the housing and the second end of the housing. A blade support portion of the cutter body is wider than the cavity, so that when the cutter body is moved into the cavity, the wall of the housing pushes the blade support portion in the radial direction relative to the longitudinal axis so that the blade is moved towards the longitudinal axis.
    Type: Application
    Filed: July 27, 2022
    Publication date: October 17, 2024
    Inventor: Daniel Carlsson
  • Publication number: 20240342393
    Abstract: Disclosed are a needle that may inject a drug in communication with a targeted depth of a target while minimizing a depth, by which the needle is inserted into the target when the drug is injected to the targeted depth of the target through the needle, whereby an unnecessary injury may be prevented from occurring as an unnecessary portion is inserted into the target, and a needle tip including the same.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 17, 2024
    Inventors: Suk Bae SEO, Ja Young KIM, Ho Joon SEO
  • Publication number: 20240342394
    Abstract: A male needless connector having a tapered elongate tip and a collar compliant with ISO standards, the collar having an outer sidewall surface with a plurality of threads for connection to corresponding inner threads of a pen needle. The male needleless connector having a taper between a distal end of the elongate tip and an inner sidewall of the elongate tip. The male needless connector being configured to receive a pen needle.
    Type: Application
    Filed: September 3, 2021
    Publication date: October 17, 2024
    Applicant: Becton, Dickinson and Company
    Inventor: Des Whitney
  • Publication number: 20240342395
    Abstract: A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member. The plunger member includes a rotatable member configured to insert the stopper member distally in the syringe interior relative to the syringe body with rotation of the rotatable member. The plunger member further includes a proximal portion proximal of the rotatable member configured to be moved distally to also insert the stopper member distally in the syringe interior relative to the syringe body to eject about microliters of fluid from the syringe interior.
    Type: Application
    Filed: April 18, 2024
    Publication date: October 17, 2024
    Applicant: Credence Medsystems, Inc.
    Inventors: Stephen H. Diaz, Alan E. Shluzas
  • Publication number: 20240342396
    Abstract: Described is a medicament delivery device comprising a case adapted to hold a container with a medicament and having a needle, a needle sleeve telescopically coupled to the case and having a first extended position relative to the case in which the needle is covered, a retracted position relative to the case in which the needle is exposed, and a second extended position relative to the case in which the needle is covered, a first indicia disposed on the needle sleeve which is visible in the first extended position and the second extended position, and a second indicia disposed on the needle sleeve and not visible in the first extended position and visible the second extended position.
    Type: Application
    Filed: May 13, 2024
    Publication date: October 17, 2024
    Inventors: Stephan Riedel, Steffen Raab, Kerstine Hemmann, Michael Caspers, Katja Hoerhold, Daniel Kerkow
  • Publication number: 20240342397
    Abstract: The disclosed tamper-evident closure encloses a medical access device, such as a vascular access device, such that it will be visibly apparent if the medical access device contained in the tamper-evident closure becomes exposed. The tamper-evident closure cannot be reapplied over the medical access device in a way to look the same as it did prior to exposing the medical access device. The tamper-evident closures comprise a securing strap with a first securing strap portion secured to the first part of the tamper-evident closure, a second securing strap portion with a free end for securing to a second part of the tamper-evident closure, and an area of weakness separating the first securing strap portion from the second securing strap portion. The force to break the area of weakness is less than the force to separate the securing strap from the first part or second part.
    Type: Application
    Filed: July 29, 2022
    Publication date: October 17, 2024
    Inventors: Alan R. Dombrowski, Adam S. Troness, Val Vossen, Dennard J. Powell
  • Publication number: 20240342398
    Abstract: A nebulizer includes a case and a nozzle. The case has an inner wall which defines an internal space. The nozzle atomizes a liquid stored in the internal space. The case includes a discharge outlet for guiding the atomized liquid to the outside of the case. The nozzle has a gas hole and a liquid hole. The gas hole ejects a gas. The liquid hole is located adjacent to the gas hole and ejects the liquid. In the internal space, the case does not have any path formed of a straight line which extends from the gas hole to the discharge outlet by passing only through the internal space.
    Type: Application
    Filed: June 25, 2024
    Publication date: October 17, 2024
    Inventors: Kenghua HSING, Miki IKEDA, Hiroaki WADA, Yohei KAWASAKI, Susumu TAKEUCHI
  • Publication number: 20240342399
    Abstract: The present disclosure relates to a medicament delivery device (100) configured to eject a dose of medicament for delivery to a user. The medicament delivery device (100) comprises a main body (1) accommodating a medicament cartridge (2), a piston rod (4) arranged at an outlet end of the medicament cartridge (2), the piston rod (4) accommodating a channel (11) an inlet end of which is arranged to be inserted in the medicament cartridge (2) for access to and transport of the medicament, and a spring (3) configured to spring load the piston rod (4) such that the spring (3) is compressed upon the piston rod (4) being moved towards a distal end of the main body (1).
    Type: Application
    Filed: August 3, 2022
    Publication date: October 17, 2024
    Inventor: Daniel Säll
  • Publication number: 20240342400
    Abstract: A smoking cessation system may include a nicotine delivery device to deliver a mixture in an aerosol form to a user, through pulmonary delivery. The mixture may include nicotine. The system may be prescription, over-the-counter, or non-prescription based. The smoking cessation system may also include a health hub to communicate with the nicotine delivery device and to control operation of the nicotine delivery device based on information. Such information may include, for example, information relating to the use of the nicotine delivery device by the user. One or more additional devices (e.g., a continuous monitoring device that detects nicotine content and use, including through metabolites such as cotinine or carbon monoxide) may communicate one or more items of the information to the health hub for the purpose of assisting the user to quit smoking.
    Type: Application
    Filed: April 4, 2024
    Publication date: October 17, 2024
    Applicant: Flik Therapeutics, Inc.
    Inventor: Brendan Heiden
  • Publication number: 20240342401
    Abstract: Embodiments described herein generally relate to apparatus and methods for verifying the concentration of mixed gas to be used for ophthalmic administration. In an embodiment is provided a method that includes introducing a first portion of mixed gas into a chamber, determining a temperature change of the first portion which is indicative of a parameter of the first portion, determining that the parameter satisfies a predetermined value, and introducing a second portion of mixed gas into a patient's eye. In another embodiment is provided a method that includes exposing an element inside a chamber to a first portion of mixed gas, determining a change in a physical characteristic of the element that changes in response to a stimulus, the physical characteristic indicative of a parameter of the first portion, determining that the parameter satisfies a predetermined value, and introducing a second portion of mixed gas into a patient's eye.
    Type: Application
    Filed: June 21, 2024
    Publication date: October 17, 2024
    Inventor: Conrad SAWICZ
  • Publication number: 20240342402
    Abstract: An insufflator (100) is operable in a set-up mode and in a normal insufflating mode. In the set-up mode, a minimum working pressure value and an optimum maximum pressure value of a working pressure range for a cavity (3) to be insufflated is determined. A microprocessor (122) in the set-up mode operates a flow controller (124) to deliver insufflating gas at a constant rate to the cavity (3). The microprocessor (122) reads signals from a pressure sensor (137) indicative of the cavity pressure and from a flow sensor (135) indicative of the flow rate of insufflating gas to the cavity (3) at predefined time intervals from the commencement of insufflating of the cavity, and determines a pressure/volume relationship (150, 153) between cavity pressure and the volume of the cavity (3) from the cumulative volume of insufflating gas delivered to the cavity (3).
    Type: Application
    Filed: April 15, 2024
    Publication date: October 17, 2024
    Applicant: Palliare Limited
    Inventor: John O'DEA
  • Publication number: 20240342403
    Abstract: The Overdose Reviver Automatic Inhaler is a method to repeatedly administer Narcan solution automatically, intranasally. When heartbeat sensors relay life-threatening low heartbeat data to a microprocessor chip the programmed functions are activated. Automatically administering atomized, pressurized Narcan solution into nostrils of an unconscious, opioid overdosed person once every two to three minutes and alert for help. The Automatic Inhaler is battery powered, automated, and mechanical. It is worn strapped to a user's neck, a nasal airline with nasal prongs, is secured in place under a user's nose via head, and nasal airline elastic straps. An electromagnetic solenoid depresses an air release valve on a pressurized air canister containing enough Narcan solution and pressurized air for at least ten one second squirts. A precautionary preemptive action for someone who knowingly is using opioids, most likely home alone. It's a method to revive oneself in case a lethal dose is ingested.
    Type: Application
    Filed: June 11, 2024
    Publication date: October 17, 2024
    Inventor: Keith Alan Roberts
  • Publication number: 20240342404
    Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 17, 2024
    Applicant: Norton (Waterford) Limited
    Inventors: Mark Milton-Edwards, Guilherme Safioti, Lena Granovsky, Michael Reich
  • Publication number: 20240342405
    Abstract: Provided is a system for determining a probability of a respiratory disease exacerbation in a subject. The system comprises an inhaler arrangement for delivering a medicament to the subject. The medicament may be a rescue medicament and/or a maintenance medicament. The inhaler arrangement has a use-detection system configured to determine an inhalation performed by the subject using the inhaler arrangement. A sensor system is configured to measure a parameter relating to airflow during the inhalation. A user interface enables user-input of an indication of a status of the respiratory disease being experienced by the subject. A processor is configured to determine the probability of the respiratory disease exacerbation based on the recorded inhalation(s) from the use-detection system, the parameter(s) received from the sensor system, and the indication received from the user interface. Further provided is a method for determining the probability of a respiratory disease exacerbation in a subject.
    Type: Application
    Filed: June 25, 2024
    Publication date: October 17, 2024
    Applicant: Norton (Waterford) Limited
    Inventors: Mark Milton-Edwards, Guilherme Safioti, Lena Granovsky, Michael Reich
  • Publication number: 20240342406
    Abstract: There is disclosed an aerosol delivery device. The aerosol delivery device includes a first aerosol first aerosol sized for pulmonary penetration; and a second aerosol sized to inhibit pulmonary penetration. The second aerosol is transmissible within at least one of: a mammalian oral cavity and a mammalian nasal cavity, and the second aerosol comprising an active component for activating at least one of: one or more taste receptors in said oral cavity and one or more olfactory receptors in said nasal cavity. The second aerosol generator includes a Venturi aperture to generate the second aerosol. There is disclosed a consumable for a substitute smoking device and a substitute smoking system. The consumable includes an airflow passage between an upstream inlet of the consumable and a downstream outlet of the consumable. The consumable also includes a porous member for passive aerosol generation. The airflow passage is constricted by the porous member to form a narrowed portion of the airflow passage.
    Type: Application
    Filed: June 21, 2024
    Publication date: October 17, 2024
    Inventors: David JONES, Chris LORD, Tom SUDLOW, Edward Ross SHENTON, Andrew AUSTIN, Tamas SAJTOS
  • Publication number: 20240342407
    Abstract: Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients. The dispensers of the invention may be used in the treatment of nocturia, primary nocturnal enuresis, incontinence, urinary frequency, diabetes insipidus, or any disease or syndrome where desmopressin therapy is useful or where safe temporary suppression of urine production may lead to beneficial health effects or increased convenience in voiding control.
    Type: Application
    Filed: November 10, 2023
    Publication date: October 17, 2024
    Inventor: Seymour Fein
  • Publication number: 20240342408
    Abstract: A liquid dispenser having a liquid reservoir, a liquid applicator and a conveying device for conveying liquid from the liquid reservoir) to the liquid applicator. The liquid dispenser has an applicator unit, on which the liquid applicator is provided, and a protective unit having a protective cover for protecting the applicator unit. The protective unit and the applicator unit can be displaced with respect to one another between a protective position and a use position. The liquid dispenser has an operating handle, via which operating handle the protective unit can be displaced from the protective position into the use position with respect to the applicator unit, and by which, in the use position, the conveying device can be actuated and liquid can be conveyed from the liquid reservoir to the liquid applicator.
    Type: Application
    Filed: April 12, 2024
    Publication date: October 17, 2024
    Inventor: Leonard WELSCH
  • Publication number: 20240342409
    Abstract: The present invention relates to systems and methods for performing a puncturing operation with improved puncture precision. The invention refers to a monitoring system comprising a first magnetic sensor attachable to a puncturing instrument (20), a second magnetic sensor (14) supportable by an endoscopic instrument (30), a field generator (16) configured for generating a variable magnetic field, and a processing unit. The processing unit (18) determines a relative position of the first magnetic sensor with respect to the second magnetic sensor and generates positional data encoding such relative position. The invention further refers to a puncturing system (100) comprising such a monitoring system (10), to a related method of generating positional data, and to a related storage device.
    Type: Application
    Filed: July 11, 2022
    Publication date: October 17, 2024
    Inventors: Roman KRUMPHOLZ, Dirk WILHELM, Daniel OSTLER-MILDNER, Andreas RANFT
  • Publication number: 20240342410
    Abstract: An exchanger conduit permits temperature and/or humidity conditioning of a gas for a patient respiratory interface. In an example embodiment, a conduit has a first channel and a second channel where the first channel is configured to conduct an inspiratory gas and the second channel configured to conduct an expiratory gas. An exchanger is positioned along the first channel and the second channel to separate the first channel and the second channel. The exchanger is configured to transfer a component (e.g., temperature or humidity) of the gas of the second channel to the gas of the first channel. In some embodiments, an optional flow resistor may be implemented to permit venting at pressures above atmospheric pressure so as to allow pressure stenting of a patient respiratory system without a substantial direct flow from a flow generator of respiratory treatment apparatus to the patient during patient expiration.
    Type: Application
    Filed: April 9, 2024
    Publication date: October 17, 2024
    Applicant: ResMed Pty Ltd
    Inventors: Liam HOLLEY, Paul Jan KLASEK, Robert Henry FRATER, Quangang YANG, Pallavi GOSAIN
  • Publication number: 20240342411
    Abstract: A gas sensor module is provided for a therapeutic gas delivery device. The gas sensor module includes a sample inlet and a sample chamber forming a flow passage fluidly connected with the sample inlet and operable to receive sample gas, where the sample chamber includes a plurality of sensor chambers in communication with one or more corresponding sensors operable to measure at least one property of the sample gas. The flow passage directs a flow of the sample gas through the gas sensor module and includes one or more turns prior to each of the plurality of sensor chambers, each turn having an angle operable to promote mixing of the sample gas and promote diffusion of the sample gas onto each of the plurality of sensors.
    Type: Application
    Filed: April 9, 2024
    Publication date: October 17, 2024
    Inventor: Peter J. Clark
  • Publication number: 20240342412
    Abstract: A head-mountable flow generator is configured to deliver a flow of breathable gas at a continuously positive pressure with respect to ambient air pressure to a patient interface in communication with an entrance to a patient's airways including at least an entrance of the patient's nares, while the patient is sleeping, to ameliorate sleep disordered breathing. The flow generator includes a motor, an impeller assembly and housing that encases the motor and the impeller assembly. The housing is configured to be mounted on the patient's head and comprises an inlet to receive the flow of breathable gas and a pair of opposing outlets to deliver the flow of breathable gas. In addition, the impeller assembly is configured to pressurize the flow of breathable gas received from the inlet, and the housing is configured to convey the pressurized flow of breathable gas through both outlets.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 17, 2024
    Inventors: Barton John KENYON, Renee Frances Flower, Enrico Brambilla, Philip Rodney Kwok