Patents Issued in November 21, 2024
  • Publication number: 20240382651
    Abstract: In one aspect, the present disclosure provides a drug delivery device comprising a collagen matrix and an anesthetic drug substance. In another aspect, the present disclosure provides methods of isolating and maturing the collagen used to make the collagen matrix. In yet another aspect, the present disclosure provides methods of making the drug delivery device from the matured collagen.
    Type: Application
    Filed: July 28, 2022
    Publication date: November 21, 2024
    Inventors: Gwendolyn Niebler, Alexandra Dietrich, Louis Pascarella
  • Publication number: 20240382652
    Abstract: This invention provides optimized solid substrates for promoting cell or tissue growth or restored function, which solid substrate comprises aragonite and is characterized by a specific fluid uptake capacity value of at least 75%, or a contact angle value of less than 60 degrees when in contact with a fluid and which is further characterized by tapered sides and tools for implantation of optimized solid substrates.
    Type: Application
    Filed: July 31, 2024
    Publication date: November 21, 2024
    Applicant: CARTIHEAL (2009) LTD.
    Inventors: Nir Altschuler, Amir Goren
  • Publication number: 20240382653
    Abstract: The present disclosure relates a modified SIS membrane for tissue repair, a preparation method therefor and a use thereof. Specifically provided are a composition comprising a fusion polypeptide-modified SIS membrane and an extracellular vesicle, as well as a preparation method for and a use of the composition. It is proved that the fusion polypeptide-mediated SIS membrane and the composition containing the SIS membrane and the extracellular vesicle have excellent biological functions, and provide a broad prospect for treating bone defects or facilitating tissue healing or bone regeneration.
    Type: Application
    Filed: October 20, 2021
    Publication date: November 21, 2024
    Inventors: Bo Zhao, Huasheng Wang, Pengfei Wei, Wei Jing, Zihao Liu
  • Publication number: 20240382654
    Abstract: The present invention relates to a chemical cross-linking based porous material for tissue regeneration and hemostasis, including an extracellular matrix of decellularized kidney tissue, and a method for production thereof. The porous material including an extracellular matrix of decellularized kidney tissues according to the present invention forms a chemical cross-linking bond, while the final product does not contain any existing cross-linking agent component, whereby the porous material can be utilized in biocompatible substances. Further, the porous material of the present invention does not only have rapid hemostasis but also delays degradation in a long term to thus exhibit tissue regeneration effects, so that the porous material is expected to be usefully applicable for treatment of different diseases due to tissue damage in a variety of tissues, or for hemostasis and tissue regeneration at removal of tissues or incision operation.
    Type: Application
    Filed: May 14, 2024
    Publication date: November 21, 2024
    Applicants: POSTECH Research and Business Development Foundation, INDUSTRY-ACADEMIC COORPERATION FOUNDATION DAEGU HAANY UNIVERSITY
    Inventors: Jae Yun KIM, Tugce SEN, Jae Yeon LEE, Dong-Woo CHO
  • Publication number: 20240382655
    Abstract: A catheter configured to release nitric oxide and chlorhexidine providing anti-platelet and antimicrobial properties is manufactured by impregnating a thermoplastic polyurethane catheter extrusion with a nitric oxide releasing compound and with chlorhexidine. Thereafter, the impregnated catheter extrusion is coated with a polyurethane coating comprising chlorhexidine and/or a nitric oxide releasing compound. In the impregnating step, the catheter extrusion may be exposed to a solvent having the nitric oxide releasing compound and chlorhexidine dissolved therein. The solvent is removed from the catheter extrusion. In the coating step, the impregnated catheter extrusion may be dip coated in a polymer solution comprising polyurethane and chlorhexidine and/or a nitric oxide releasing compound in a suitable solvent. The nitric oxide releasing compound, impregnated and/or coated, may be selected from s-nitroso-n-acetylpenicillamine (SNAP), s-nitrosoglutathione (GSNO), and mixtures thereof.
    Type: Application
    Filed: July 30, 2024
    Publication date: November 21, 2024
    Inventors: James Freasier, Brendan Laine, Gidon Ofek
  • Publication number: 20240382656
    Abstract: The present disclosure concerns drug coating layers for medical devices that cover an exterior surface or portion thereof. The drug coating layers include a bioabsorbable material with a therapeutic or a polymer microparticle loaded with a therapeutic embedded therein. As the material is bioabsorbed the therapeutic is released and available to provide localized activity in a subject. In some aspects, the drug coating layer is of a material that due to the body temperature of the subject becomes tacky and allows for adhesion to the vessel wall.
    Type: Application
    Filed: October 5, 2021
    Publication date: November 21, 2024
    Inventors: Jeffrey Wang, Cyal Lecy, Michaella Kavanagh, Logan Grace, Emily Goel, Dillon Mir
  • Publication number: 20240382657
    Abstract: A method for transfusing blood using a syringe pump is disclosed. The method includes connecting a blood supply line to an upstream connection of a check valve, an intravenous transfusion line to a downstream connection of the check valve, and a syringe pump to a second upstream connection of the check valve, and activating the syringe pump to automatically retract and drive a plunger of the syringe pump, repeatedly, according to a pump rate programmed into the syringe pump according to the automatic retracting and driving of the plunger. By this mechanism, a blood product is automatically withdrawn from the blood supply line, through the check valve, and into a chamber of a syringe loaded into the syringe pump during each cycle of the automatic retracting of the plunger, and provided through the intravenous transfusion line from the chamber during each cycle of the automatic driving of the plunger.
    Type: Application
    Filed: September 13, 2022
    Publication date: November 21, 2024
    Inventors: Vishnu MALLAPRAGADA, Janice R. PAK
  • Publication number: 20240382658
    Abstract: A container for collecting, storing and dispensing fluid, as in enteral feeding and/or medication deliver to neonatal infants. The container includes a hollow tube with a body, a first end, a second end, and an outer diameter. The hollow tube is configured to receive a movable plunger that advances and retracts therein to define a variable contained volume. The container also includes a sealing head assembly removably mounted at an end of the hollow tube. The sealing head assembly has a diameter or outside dimension that is substantially similar or identical to a corresponding outside diameter or dimension of the hollow tube, so that the container lies flat within the receiver of an enteral feeding pump.
    Type: Application
    Filed: July 29, 2024
    Publication date: November 21, 2024
    Inventors: Aaron N. Ingram, Anthony C. Lair, Mark Martin Costello, Tony Doherty
  • Publication number: 20240382659
    Abstract: Provided herein are a control arrangement, a solution generation apparatus, and a method for evaluating an integrity of a forward osmosis (“FO”) membrane of a FO-device in a dialysis solution generation apparatus. The FO-device is configured to be used in a FO session for diluting a dialysis concentrate in a process for producing a dialysis solution. The FO-membrane separates a first side from a second side of a FO-device. The method comprises passing electrolyte solution at the first side and passing low-electrolyte solution at the second side. The method further comprises measuring conductivity of a solution generated from the second side and evaluating the integrity of the FO-membrane based on whether the measured conductivity meets conductivity criteria. The conductivity criteria include a conductivity of a solution generated from the second side with an equivalent electrolyte solution and an equivalent low-electrolyte solution using a FO-membrane that is intact or has integrity.
    Type: Application
    Filed: April 5, 2022
    Publication date: November 21, 2024
    Inventor: Christian VARTIA
  • Publication number: 20240382660
    Abstract: A peritoneal dialysis (“PD”) system includes a cycler having a weigh scale, a chamber for weighing by the weigh scale, a heater, a plurality of valves, a pump, and a control unit operable with the weigh scale, the heater, the plurality of valves and the pump; and a disposable set including a PD fluid container fitting within the chamber for weighing and heating, a supply line in fluid communication with the PD fluid container, a drain container fitting within the chamber for weighing, a drain line in fluid communication with the drain container, and a patient line positioned on an opposing side of the pump from the supply line and the drain lines, wherein the control unit is configured to operate the plurality of valves and the pump to pump used dialysis fluid to the drain container and fresh dialysis fluid from the PD fluid container.
    Type: Application
    Filed: February 24, 2022
    Publication date: November 21, 2024
    Inventors: Olof JANSSON, Christian Antero Vartia, Sture Hobro
  • Publication number: 20240382661
    Abstract: Systems and methods for perfusing a treatment solution into the blood stream of particular organs while isolating those organs from the systemic vasculature as a whole. By deploying both collection and supply catheters, some having balloons on their distal ends, to particular locations within the body, various organs can be isolated so that the treatment solution can be delivered directly thereto. By isolating the organs, any side effects that may occur from a systemic introduction of the treatment solution are avoided. The method may be used to isolate not just organs, but specific tumors within certain organs for oncology treatment.
    Type: Application
    Filed: May 16, 2024
    Publication date: November 21, 2024
    Inventors: Mark Dehdashtian, Christopher Aguayo, Johannes Holzmeister, Ole Blank, Maximilian Emmert, Nikola Cesarovic
  • Publication number: 20240382662
    Abstract: In examples described herein, a system includes an elongate member configured to be introduced into vasculature of a patient. The elongate member includes a pressure sensor configured to generate a pressure signal indicative of pressure in the vasculature adjacent the needle. The system includes processing circuitry configured to receive the pressure signal from the pressure sensor, detect, based on the pressure signal, dislodgment of the elongate member from the vasculature, and generate an output in response to detecting the dislodgment of the elongate member from the vasculature.
    Type: Application
    Filed: April 24, 2024
    Publication date: November 21, 2024
    Inventors: Daniel Bloomberg, VenKatesh Manda
  • Publication number: 20240382663
    Abstract: A heart lung machine (HLM) includes: a pump actuator; an actuator control unit (ACU) operably connected to the pump actuator; a processing unit configured to receive a set of parameter data from the actuator; a display device configured to present a subset of the set of parameter data; and an input control device operably connected to the pump actuator. The input control device includes a rotatable knob. The ACU may be configured to: determine that the pump actuator has been stopped in response to a pump-stop trigger event; determine that the rotatable knob has been rotated to a first position; and in response to determining that the rotatable knob has been rotated to the first position, starting the pump actuator.
    Type: Application
    Filed: July 31, 2024
    Publication date: November 21, 2024
    Applicant: LivaNova Deutschland GmbH
    Inventor: Friedemann Schubert
  • Publication number: 20240382664
    Abstract: A method includes calculating in real-time a correlation between vacuum readings and pressure readings of respective aspiration and irrigation channels of a phacoemulsification handpiece engaged in a phacoemulsification procedure in an eye. Upon detecting an increase in the vacuum readings and an increase in the pressure readings, a current level of the correlation is checked. Provided that the current level of the correlation is above a given value, an anti-vacuum surge (AVS) mechanism is activated, the AVS mechanism fluidly coupled with at least one of the irrigation and aspiration channels.
    Type: Application
    Filed: May 15, 2023
    Publication date: November 21, 2024
    Inventors: Vadim Gliner, Eran Haas, Assaf Govari
  • Publication number: 20240382665
    Abstract: An anti-backflow nasal aspirator, comprising: a housing, wherein a control assembly and a suction assembly are installed in the housing, and the suction assembly is opened or closed by the control assembly; a collection assembly, hermetically installed on the housing, and the collection assembly is hermetically docked with the suction assembly; the collection assembly is provided with a collection cavity; a suction nozzle, installed at the input end of the collection assembly; a diversion bracket, installed in the collection assembly. The nasal mucus is diverted through the diversion bracket to prevent the nasal mucus from entering the air passage and causing a short circuit of the main board, and through the structure of the joint between the diversion bracket and the collection cup mask, it can effectively prevent nasal mucus from diverting, which is more hygienic.
    Type: Application
    Filed: May 31, 2023
    Publication date: November 21, 2024
    Inventor: Yuyu Cao
  • Publication number: 20240382666
    Abstract: Apparatuses, systems, and methods for optimizing fluid storage canisters for use in negative pressure therapy systems are described. A fluid storage canister includes a first wall and a second wall coupled to the first wall. The canister has a chamber disposed between the first wall and the second wall. The chamber is configured to be sealed from an ambient environment and to store fluid. A pathway is disposed between the first wall and the second wall. The pathway is configured to be open to the ambient environment. There is a barrier separating the pathway from the chamber. The barrier is configured to permit evaporated fluid in the chamber to transmit through the barrier into the pathway.
    Type: Application
    Filed: August 23, 2022
    Publication date: November 21, 2024
    Inventors: Benjamin A. PRATT, Thomas A. EDWARDS
  • Publication number: 20240382667
    Abstract: A device for wound irrigation and debridement includes a body extending along a longitudinal axis. The body comprises an interior region and an opening such that that the interior region and the first opening are configured to transfer an irrigation fluid. The body comprises a compliant region having a first stiffness and a debridement region having a different second stiffness. The compliant region defines a distal surface. In a first configuration, the compliant region defines a first axial dimension, the distal surface engages a target body region, and the debridement region is axially offset from the distal surface and disengaged from the target body region. In a second configuration, the compliant region is compressed to define a second axial dimension less than the first axial dimension, thereby engaging the debridement region with the target body region, and the distal surface engages the target body region.
    Type: Application
    Filed: July 29, 2024
    Publication date: November 21, 2024
    Applicant: The Regents of The University of Michigan
    Inventors: Paul Stephen CEDERNA, Nishant GANESH KUMAR, Jeffrey Stephen PLOTT
  • Publication number: 20240382668
    Abstract: A fluidics system includes a cassette having a saline subsystem, a contrast subsystem, and a vacuum subsystem. The fluidics system further includes a splitter and a first tubing set coupled to the cassette and splitter, the first tubing set having a single saline channel, a single contrast channel, and a single vacuum channel. The fluidics system further includes two or more hub assemblies, at least one of the two or more hub assemblies configured to have a third saline flow-path, a third contrast flow-path, and a third vacuum flow-path to provide saline, contrast and vacuum to the lumen of a catheter coupled to the at least one of the two or more hub assemblies. The fluidics system further includes a second tubing set having a plurality of tube groups, each tube group coupled to the splitter and to one of the two or more hub assemblies.
    Type: Application
    Filed: May 16, 2024
    Publication date: November 21, 2024
    Inventors: Kyle Bartholomew, Tabish Mustufa, Vedant Chhaya
  • Publication number: 20240382669
    Abstract: Apparatus, system and method for heating fluid from a plurality of fluid sources. A heating chamber top portion includes a plurality of fluid inlet tubes configured to pass fluid from the plurality of fluid sources. A heating chamber may be coupled to the heating chamber top portion, the heating chamber collectively receives at least some of the fluid from the plurality of fluid sources. At least one heating element configured within the heating chamber heats the received fluid from the plurality of fluid sources. An agitator mixes the received fluid from the plurality of fluid sources in the heating chamber, wherein the agitator is configured to mix the received fluid from the plurality of fluid sources by rotationally turning within the heating chamber.
    Type: Application
    Filed: July 29, 2024
    Publication date: November 21, 2024
    Inventors: William CARAPEZZA, Rodney MEDLEY
  • Publication number: 20240382670
    Abstract: A syringe pump system for delivering controlled delivery of fluids from a syringe. The syringe pump system includes a keyed coupling and a motorized syringe pump. The keyed coupling includes an identifiable key piece that identifies which application or area of therapy is desired. The syringe pump includes a pump housing, a sliding key bed for receiving and reading the identifiable key piece of the keyed coupling, and a plunger actuator for actuating a plunger of the syringe. An internal software may be used to determine the correct drug or nutritional libraries and syringe specifications preprogrammed into the pump.
    Type: Application
    Filed: April 26, 2024
    Publication date: November 21, 2024
    Inventor: Benjamin Martin DAVIS
  • Publication number: 20240382671
    Abstract: An infusion device (1) for administering a medical fluid to a patient (P) comprises a receptacle (12) for receiving a syringe (2). the syringe (2) comprising a tube (20) and a piston (21) movable with respect to the tube (20), a pusher device (11) for exerting a force onto the piston (21) for delivering a medical fluid from the tube (20) towards a patient (P). A sensor device (14) is arranged on the pusher device (11) for measuring a force exerted on the piston (21) by the pusher device (11). A holding element (17) is arranged on the pusher device (11), the holding element (11) being movable with respect to the pusher device (11) between a non-actuated position, in which the holding element is configured to hold the piston (21) on the pusher device (11), and an actuated position for releasing the piston (21) from the pusher device (11). A processing device (15) serves for controlling operation of the infusion device (1).
    Type: Application
    Filed: September 7, 2022
    Publication date: November 21, 2024
    Inventor: Rémy Wolff
  • Publication number: 20240382672
    Abstract: Provided is an electroosmotic pump including a housing including a shaft hole, a membrane disposed between a first space arranged in a direction away from the shaft hole and a second space adjacent to the shaft hole, a first electrode body and a second electrode body arranged at opposite sides based on the membrane, a shaft extending to an outside of the housing through the shaft hole, and a first fluid included in an internal space of the housing.
    Type: Application
    Filed: August 1, 2024
    Publication date: November 21, 2024
    Inventors: Jesse Jae Jin Kim, Yong Chul Song, Seung Ha Kim, Dae Jong Park
  • Publication number: 20240382673
    Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.
    Type: Application
    Filed: April 22, 2024
    Publication date: November 21, 2024
    Inventors: Adam B. McCullough, Erich Coiner, Alan D. Payne
  • Publication number: 20240382674
    Abstract: An inserter assembly comprising a first unit including a skin contacting face which surrounds an opening and a second unit housed within the first unit. The second unit comprises an infusion set base disposed within the opening and having a bottom face which is substantially level with the skin contacting face and covered at least partially with adhesive and further comprising a spring biased insertion assembly. The second unit further comprising a cannula sub assembly carried by an insertion sharp of the insertion assembly. The spring biased insertion assembly and a cannula of the cannula sub assembly are driven into skin and the cannula sub assembly is coupled into the infusion set base by an insertion spring which is released from an energy storing state after the skin has been tugged upward beyond a certain distance by the adhesive as the inserter assembly is withdrawn from the body.
    Type: Application
    Filed: July 25, 2024
    Publication date: November 21, 2024
    Inventor: Richard J. Lanigan
  • Publication number: 20240382675
    Abstract: An apparatus method, and system for detecting a leaking occluder valve is disclosed. At least one measurement instrument is connected to a fluid within a fluid tubing upstream or downstream of a pump element of an infusion device. The pump element is configured to periodically cause a compression of the fluid tubing and to isolate a downstream portion of the fluid tubing from an upstream portion of the fluid tubing when the pump element is operating under a normal operating condition. A response of the fluid is measured when the pump element is caused to compress the fluid tubing and a determination is made, based on the response whether the compression has fluidically isolated the downstream portion from the upstream portion. One or more shims may be inserted into the occluder valve to move the platen away from the pump element during the test to determine a degree of fault.
    Type: Application
    Filed: September 10, 2021
    Publication date: November 21, 2024
    Inventors: Daniel ABAL, Brendan John BURGESS, Ramkumar SUBRAMANIAN
  • Publication number: 20240382676
    Abstract: A method for readying a fluid sensor associated with a medical device includes attaching a flow restrictor to a fluid outlet of the fluid sensor. The fluid sensor includes a fluid channel, a fluid inlet at a first end of the fluid channel configured to couple to an outlet of an administrable fluid source, and the fluid outlet at a second end of the fluid channel. Fluid is delivered from the administrable fluid source to the fluid channel through the fluid inlet. A syringe actuation device including a force limiting device may be used to deliver the fluid. The fluid is pressurized in the fluid channel between the fluid inlet and the flow restrictor to wet an interior surface of the fluid channel with the fluid. The flow restrictor is removed from the fluid outlet.
    Type: Application
    Filed: July 30, 2024
    Publication date: November 21, 2024
    Inventors: Kaushal Verma, Brandi Ford, Shawn Wayne DeKalb, Hong Zhu
  • Publication number: 20240382677
    Abstract: An injection device may include a housing, a container disposed within the housing, the container enclosing a fluid and having a first end and a second end, a conduit movable relative to the container, wherein the conduit is not in fluid communication with the fluid enclosed by the container while in a first position, and is in fluid communication with the fluid enclosed by the container and configured to deliver the fluid from the container to a patient while in a second position, and a lock that is removable from the housing, the lock having a first portion and a second portion.
    Type: Application
    Filed: May 16, 2024
    Publication date: November 21, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Bryan C. GRYGUS, Trevor Langley, Daniel Halbig, Ross Kenyon, Alfred Marino, Wayne Phillips, Jeff Moore, Sten Nygaard, Jan Norup, David Farrage, Jeremy Odegard, Jeremy McNamara
  • Publication number: 20240382678
    Abstract: A training device may include a housing having a tissue-engaging surface, an activating switch configured to be moved from a deactivated configuration to an activated configuration, a touch sensor disposed on the tissue-engaging surface and configured to detect contact with skin or synthetic injection surface, a motor, and a controller coupled to the motor. The controller may be configured to receive a first indication that the activating switch has been moved to the activated configuration, receive a second indication that the touch sensor has detected contact with skin or synthetic injection surface; and the motor to be driven for a predetermined period of time.
    Type: Application
    Filed: May 16, 2024
    Publication date: November 21, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Ashley JOHANNES, Jeff MOORE
  • Publication number: 20240382679
    Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Inventors: John Michael Dobbles, Apurv Ullas Kamath, Aarthi Mahalingam, James H. Brauker
  • Publication number: 20240382680
    Abstract: Methods and systems may quantify how much contrast fluid is injected into a patient by a powered fluid injector. A controller of the powered fluid injector can receive a command from a user to begin dispensing contrast fluid. The controller may determine whether a hemodynamic pressure signal is present from a pressure sensor in fluidic connection with the vasculature of the patient. The powered fluid injector may dispense a quantity of contrast fluid in response to the command. The controller may add the quantity of contrast fluid to an injection quantity if the hemodynamic pressure signal is present just prior to and/or just after the quantity of contrast fluid is dispensed. The controller may refrain from adding the quantity of contrast fluid to the injection quantity if the hemodynamic pressure signal is not present just prior to and/or just after the quantity of contrast fluid is dispensed.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Inventor: Blaise D. Porter
  • Publication number: 20240382681
    Abstract: The present disclosure generally provides for a method of assembling a medical device, comprising forming a first assembly comprising a main body, a needle mechanism, a sterile connector operatively connected with a portion of the needle mechanism and configured to receive a cartridge. The needle mechanism and the sterile connector form a fluid path assembly which attaches with the main body forming the first assembly. The method further includes forming a second assembly comprising a base end and a translation mechanism, the translation mechanism is configured to engage the cartridge, and combining the first assembly and the second assembly.
    Type: Application
    Filed: May 16, 2024
    Publication date: November 21, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventor: Bryan C. GRYGUS
  • Publication number: 20240382682
    Abstract: A. An injection device kit for the self-administration of an injection of solution that includes a body portion configured for engagement with a cartridge containing the solution and an injection needle where the body portion includes an injection component having an actuation mechanism for inserting the injection needle of the cartridge and for injecting the solution in the cartridge and a safety mechanism on the body portion and configured to prevent injection unless released.
    Type: Application
    Filed: February 5, 2024
    Publication date: November 21, 2024
    Applicant: DJ Medical, LLC
    Inventors: Daniel Schneider, Jay Duckson
  • Publication number: 20240382683
    Abstract: A device for administering a fluid is provided, with a cylinder, a piston, a piston rod, a receiving block (10), a nonreturn valve, a tensioning device, a ramp, a motor (12), a ramp track, a roller and a driver (50).
    Type: Application
    Filed: July 15, 2024
    Publication date: November 21, 2024
    Applicant: INTERVET INC.
    Inventors: Frank Altermann, Dominic Kamenzin, Manuel Mattes, Robin Sauter, Thomas Schmidt, Daniel Seeh
  • Publication number: 20240382684
    Abstract: A syringe assembly includes a syringe having a reservoir and a distal tip, a cap component engaged with the distal tip, and an identification sleeve engaged with the cap component via one or more engagement features extending from at least one of the cap component and the identification sleeve. The identification sleeve comprises an RFID tag to allow the traceability of said syringe before final product labelling.
    Type: Application
    Filed: September 19, 2022
    Publication date: November 21, 2024
    Inventors: Alfred Leibbrand, Sébastien Jouffray
  • Publication number: 20240382685
    Abstract: Methods for manufacturing injector devices, including positioning a stopper of the injector device in a tubular member such that an outer side of the stopper is engaged with an inner surface of the tubular member and modifying the outer side of a stopper by causing relative motion between the stopper and the tubular member, the relative motion including one or both of rotational motion and vibrational motion.
    Type: Application
    Filed: August 27, 2021
    Publication date: November 21, 2024
    Inventors: Edward H. Cully, William G. Hardie
  • Publication number: 20240382686
    Abstract: An electronic module for a drug delivery device comprises a dose setting and drive mechanism configured to perform a dose setting operation for setting a dose to be delivered by the drug delivery device and a dose delivery operation. The module comprises a processor, a sensor arrangement, a communication unit with a wireless communication interface connected to the processor and operable to establish communication with another device and to transfer data to the other device, an electronic user feedback generator, a memory, and a power source. The processor is configured to prevent data transfer by the communication interface during operation of the electronic user feedback generator and/or of the sensor arrangement, and/or limit the amount of data transferred by the communication interface at any one time by limiting the packet size of the data transferred by the communication interface, and/or limit the rate at which data is transferred.
    Type: Application
    Filed: September 22, 2022
    Publication date: November 21, 2024
    Inventors: Hester Jane Corne, John Whitehouse
  • Publication number: 20240382687
    Abstract: The present disclosure refers to an electronic module for a drug delivery device comprising a dose setting and drive mechanism, configured to perform a dose setting operation for setting a dose to be delivered by the drug delivery device and a dose delivery operation for delivering the set dose. The electronic module comprises at least one processor, a sensor arrangement connected to the at least one processor and operable to generate measurement data indicative of the dose setting operation and/or the dose delivery operation, a first communication unit with a wireless communication interface connected to the at least one processor and operable to establish an encrypted wireless communication with a second communication unit of another device and to transfer data to said other device, a memory for storing measurement data, and a power source connected to the at least one processor.
    Type: Application
    Filed: September 22, 2022
    Publication date: November 21, 2024
    Inventor: Christopher Knorr
  • Publication number: 20240382688
    Abstract: A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Inventors: Frank Erbstein, Paul Richard Draper, Robert Frederick Veasey, David Aubrey Plumptre, Joseph Butler
  • Publication number: 20240382689
    Abstract: A method for tuning of at least one threshold of a sensor of a drug delivery device or of a drug delivery add-on device is disclosed.
    Type: Application
    Filed: September 22, 2022
    Publication date: November 21, 2024
    Inventors: Jonathan Jason Drake, Anthony Paul Morris, Ronald Antony Smith
  • Publication number: 20240382690
    Abstract: An injection device comprising: an energy source configured to power an electronic system of the injection device; one or more sensors in communication with the energy source, the one or more sensors configured to cause an activation signal to be provided to the energy source to cause the energy source to enter a powered state from a sleep state; and a processor configured to facilitate one or more functions of the injection device when the injection device is in the powered state.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Inventors: Michael Schabbach, Johannes Alpers, Ganesh Appusamy Vedhachalam, Jörg Bigalke, Martin Rausch, Anna Baccaro
  • Publication number: 20240382691
    Abstract: An autoinjector includes a case adapted to hold a medicament container having a needle, a needle shroud slidably disposed in the case and translatable between an extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed, and a plunger slidably disposed in the case. The case includes a rib. The plunger includes a plunger boss adapted to abut the rib and the needle shroud when the needle shroud is in the extended position and disengage the rib when the needle shroud is in the retracted position to allow the plunger to translate axially relative to the case.
    Type: Application
    Filed: July 30, 2024
    Publication date: November 21, 2024
    Inventor: Thomas Kemp
  • Publication number: 20240382692
    Abstract: An object of the present disclosure is to provide a staked-in needle prefilled syringe formulation containing an antibody engineered by a mutation to histidine, which reduces the difficulty in pushing out a drug and the risk of causing clogging in a needle. The staked-in needle prefilled syringe formulation can be produced by a simple method on an industrial scale. The present prefilled syringe formulation is characterized by having an elastomeric needle shield having a low zinc leaching capacity.
    Type: Application
    Filed: July 27, 2021
    Publication date: November 21, 2024
    Applicants: Chugai Seiyaku Kabushiki Kaisha, F. Hoffmann-La Roche AG
    Inventors: Masakazu Fukuda, Shogo Yamashita, Yuji Yamanaka, Robert Mueller, Kewei Yang
  • Publication number: 20240382693
    Abstract: An injection system has a brace; a needle inside the brace in a retracted position; a mechanism operable to drive the needle from the retracted position to an extracted position; and a fluid dispenser fluidly connected to the needle. An adjustable fastener secures the brace to a body part. The injection system further includes an unmanned vehicle to carry and deploy the brace; a speaker; a microphone; a memory storing an application; and a processor which executes the application to cause the speaker and microphone to operate as a communication device and/or to cause the mechanism to extract the needle, cause the injection system to administer a dosage through the needle, and cause the mechanism to retract the needle. One or more sensors detect a position or pressure of the brace with respect to a body part. The needle may be an intravenous needle or an intraosseous needle.
    Type: Application
    Filed: May 20, 2023
    Publication date: November 21, 2024
    Inventor: Onier Villarreal Alejandro
  • Publication number: 20240382694
    Abstract: A tracking system including a first connector having a needle extending from the first connector and a needle guard circumferentially surrounding the needle, a second connector removably coupled to the first connector, the second connector having an opening configured to receive the needle when the first connector is coupled to the second connector, a wireless transmitter disposed on one of the first connector and the second connector, the wireless transmitter configured to wirelessly communicate with an external device, and a shield coupled to one of the first connector and the second connector, the shield configured to axially move relative to the wireless transmitter to block and unblock the wireless transmitter.
    Type: Application
    Filed: May 15, 2023
    Publication date: November 21, 2024
    Inventor: Shawn Wayne DEKALB
  • Publication number: 20240382695
    Abstract: An injection system includes a molded body member having a body connection member at a distal end of the molded body member. The system also includes a needle hub assembly coupled to the distal end of the molded body member. The needle hub assembly includes a needle hub coupled to the body connection member of the molded body member, a needle coupled to the needle hub, and a barbed band disposed around a proximal end of the needle hub and having a barb. The barbed band allows rotation of the needle hub assembly relative to the body connection member in a first direction, while preventing rotation of the needle hub assembly relative to the body connection member in a second direction.
    Type: Application
    Filed: May 2, 2024
    Publication date: November 21, 2024
    Applicant: CREDENCE MEDSYSTEMS, INC.
    Inventors: Mina M. Leung, Jeff Tillack, Stephen H. Diaz, Alan E. Shluzas
  • Publication number: 20240382696
    Abstract: A visualisation aid device has a flexible PCB with a ring of surface mount LEDs around a circular opening. The LEDs emit at a wavelength to provide vein visualisation through a skin area exposed by the opening in use. A transparent membrane extends across the needle-access opening, and it has an adhesive on its skin-facing distal side. After insertion of the needle with the benefit of visualisation by the LEDs the substrate may be removed leaving only the membrane maintaining a sterile environment around the puncture site and helping to retain the needle in place.
    Type: Application
    Filed: April 21, 2022
    Publication date: November 21, 2024
    Applicant: MCAS DESIGN LIMITED
    Inventors: Marie CASEY, Juan F. MARTINEZ, Andrew DE JUAN, Robert BUGGY, Manuel CABALLERO
  • Publication number: 20240382697
    Abstract: A blood vessel visualization device for visualizing a blood vessel of a living body in a site to be visualized that includes a first surface and a second surface on a side opposite the first surface, includes: an attachment portion attachable to and detachable from the site to be visualized; and an irradiation unit including a light source unit for irradiating the first surface with near-infrared light. The attachment portion includes a wavelength converter including a wavelength conversion material that converts the near-infrared light into visible light, the attachment portion being fixable to the site to be visualized in a state in which the wavelength converter is in contact with the second surface.
    Type: Application
    Filed: July 29, 2024
    Publication date: November 21, 2024
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Shota TSUMAKI
  • Publication number: 20240382698
    Abstract: A blood vessel visualization member for visualizing a blood vessel of a living body includes: a sheet body that is affixable to a surface of a site to be visualized, the sheet body including: a wavelength converter including a wavelength conversion material that converts near-infrared light into visible light, and an adhesive portion provided on the wavelength converter.
    Type: Application
    Filed: July 29, 2024
    Publication date: November 21, 2024
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Shota TSUMAKI, Takayuki YOKOTA
  • Publication number: 20240382699
    Abstract: An electronic system (700) being configured and a method for determining data related to the approach of end of life of a drug delivery device (1) are disclosed, wherein the determining of data related to the approach of end of life of the drug delivery device is based one or more of the following: an evaluation of the voltage of an internal battery (29) of the drug delivery device (1) or a drug delivery add-on device; a detection of an error of the drug delivery device (1) or drug delivery add-on device, wherein the error is related to end of life of the drug delivery device (1); an evaluation of a storage capacity of a memory (24) for records of doses expelled with the drug delivery device (1).
    Type: Application
    Filed: September 22, 2022
    Publication date: November 21, 2024
    Inventors: Hester Jane Corne, Jonathan Jason Drake, Paul Richard Draper, Ronald Antony Smith
  • Publication number: 20240382700
    Abstract: The present disclosure provides a spray head and a device for intranasal spraying of liquid medicine, comprising: a nozzle, which has a flow channel running through the axial direction, and the distal and proximal ends of the flow channel are the flow channel outlet and inlet, respectively; a water core circumferentially arranged with a water trough configured inside the flow channel; and the outlet tube, curved in shape, comprising a parallel section and an inclined section integrally connected. The end of the inclined section extends from the flow channel inlet to the inside of the flow channel and is circumferentially sealed to the inner wall of the flow channel, so that when the fluid flows in from the parallel section, it flows out from the inclined section into the inside of the flow channel and after passing through the water trough, it ejects from flow channel outlet.
    Type: Application
    Filed: May 12, 2023
    Publication date: November 21, 2024
    Inventors: Jingyi Liu, Zhutuo Chen