Abstract: An apparatus is disclosed for practicing a method of treating viruses in the nasal mucosa. Vapor is generated, heated and delivered to the nasal mucosa in intermittent bursts, timed to coincide with inhalation. Control circuits are provided to maintain the temperature of the vapor at the point of delivery at a level greater than that necessary to kill viruses in the nasal mucosa. Timing circuits can synchronize the vapor delivery with a breathing cycle with heated vapor being supplied during inhalation and blocked during exhalation. Other circuits terminate operation when liquid is insufficient or after a predetermined timed interval.

Abstract: A protection circuit, configured to detect and suppress electrical pre-arcing and arcing conditions in a resistive heater wire circuit, comprises a transient voltage suppressor, signal level sensing load coupled to the output of the voltage suppressor, detection and control circuitry, and a high-speed switch or electrical gate. The control circuitry is configured to control the operation of the switch, coupled between said control circuitry and the heater wire, wherein the switch is opened in response to an electrical pre-arcing or arcing condition or a short circuit condition.

Abstract: A humidification apparatus for humidifying a gas flow to be supplied to a patient or other person in need of such gas is provided. A first temperature sensor is provided for sensing the temperature of the gas flow substantially at an outlet of a humidification chamber and a second temperature sensor is provided for sensing the temperature of the gas flow substantially at the patient end of the conduit. A display is provided for display of temperature information to a user. A controller or processor is configured or programmed to receive input from the temperature sensors and to output a signal to the display to cause a temperature to be displayed to the user which is the lower of the temperature sensed by temperature sensors.

Abstract: A breathing gas humidifier system for a patient includes a replaceable, closed water reservoir (1) with stable pressure, provided for receiving a water reserve for the breathing gas humidifier system. An intermediate storage unit (4) with water is closed from the environment and is located under the water reservoir. The water reservoir (1) and the intermediate storage unit (4) have a valve (16, 14) each, with one of the valves cooperating with the other valve, so that there is a flow connection between the water reservoir (1) and the intermediate storage unit (4) only when the water reservoir (1) is received in a connector (2) of the intermediate storage unit (4). The intermediate storage unit (4) is connected via a water connection line (5) located below the water level to a heated evaporator chamber (7), which opens above the water evaporating at the boiling point into the breathing gas line to a patient.

Abstract: A humidifier apparatus for operating at an air pressure is disclosed for use with a respiratory therapy breathing apparatus that provides a breathable gas supply to patients requiring higher concentrations of liquid vapor and gas pressure. The humidifier apparatus includes a feed liquid supply bag in fluid communication with a humidifier cartridge via a conduit. The conduit enables air to flow therethrough to equalize air pressure between the humidifier cartridge and the feed liquid supply bag in response to liquid being supplied to the humidifier cartridge.

Abstract: A method of humidifying a gas that includes supplying a gas to a surface of a humidification material that readily absorbs moisture and readily releases moisture when exposed to a dry environment and generating turbulence in the gas as it passes over the surface of the humidification material.

Abstract: Treatment of pulmonary disorders associated with hypoxemia and/or smooth muscle constriction and/or inflammation comprises administering into the lungs as a gas compound with an NO group which does not form NO2/NOx in the presence of oxygen or reactive oxygen species at body temperature. Treatment of cardiac and blood disorders, e.g., angina, myocardial infarction, heart failure, hypertension, sickle cell disease and clotting disorders, comprises administering into the lungs as a gas, a compound which reacts with cysteine in hemoglobin and/or dissolves in blood and has an NO group which is bound in said compound so that it does not form NO2/NOx in the presence of oxygen or reactive oxygen species at body temperature. Exemplary of the compound administered in each case is ethyl nitrite.

Abstract: An apparatus for humidifying breathable gas includes (a) at least one humidifier part configured to retain a body of liquid therein and defining at least one chamber therein, (b) an inlet communicated with an interior of the at least one humidifier part and connectable to a blower outlet, and (c) an oulet communicated with the interior of the at least one humidifier part and connectable to a patient supply conduit. The at least one chamber is arranged such that liquid from the body of liquid is prevented from exiting the at least one humidifier part through the inlet thereof when the at least one humidifier part is rotated from a working, upright orientation.

Abstract: An aerosol generating device includes a housing, a heater and an optional mouthpiece. The heater volatilizes liquid within a flow passage and forms an aerosol in the mouthpiece. An aerosol confinement sleeve is disposed to control the size distribution of the aerosol.

Abstract: A humidifier and humidity sensor for use with a breathing assistance apparatus. The humidity sensor senses absolute humidity, relative humidity and/or temperature at both the patient end and humidifier end. The humidifier may also include provision to both control independently the humidity and temperature of the gases. Further, a chamber manifold facilitates easy connection of the humidifier to various outlets, inlets and sensors. A heated conduit provides a more effective temperature profile along its length.

Abstract: A disposable active humidifier for the mechanical ventilation of a patient, which has the particularity that it comprises a cartridge which forms a humidification chamber which is delimited by an inlet and by an outlet and can be interposed in the ventilation circuit. The cartridge has an interspace which is externally delimited by a heat exchange surface and is internally delimited by a hydrophobic membrane which surrounds the humidification chamber. A humidification fluid, originating from a bottle or bag, can be introduced in the interspace.

Abstract: A method is provided for generating an aerosol. The method includes preparing a solution formed of a first component in a liquid component such that after volatilization of the liquid component by passing the solution through a flow passage while heating the solution, an aerosol is formed having a predetermined particle size distribution of the first component, wherein the solution is prepared such that the amount of the first component therein is sufficient to achieve the predetermined particle size distribution of the first component. The method also includes passing the solution through the flow passage while heating the solution to a temperature sufficient to volatilize the liquid component, wherein the flow passage comprises an outlet through which the first component and the volatilized liquid component flow, and wherein an aerosol is formed.

Abstract: To provide a unit for adjusting humidification capable of improving inconveniences that may otherwise be caused to occur due to damages, while sustaining the humidifying ability and other performance that are to be originally achieved by the humidification adjusting unit. Around the outer surface of the exothermic member 13 are wound multiple hollow fibers 14 each having a minute diameter and having a peripheral wall with minute openings each being large enough to allow water vapor to permeate therethrough yet small enough to fail to permeate water therethrough, and the multiple hollow fibers 14 and the exothermic member 13 are inserted tightly into an extendable mesh cover tube 15 in engagement therewith. In order to perform humidification, water to be supplied to the multiple hollow fibers 14 is warmed by the exothermic member 13 to generate water vapors.

Abstract: An aerosol generator and methods of delivering aerosol to a user inhaling on a mouthpiece when a pressure drop is detected within the mouthpiece are disclosed. A medicated fluid passing through a capillary passage is heated to vaporize the fluid and form the aerosol by condensation or mixture of the vaporized fluid with admixed air. A metering chamber allows consistent delivery of precise doses of fluid to the capillary passage. Once the pressure drop is detected, aerosol can be quickly delivered to the user as the user begins to inhale on the mouthpiece. The quick delivery of aerosol provides more efficient use of the user's lung capacity.

Abstract: An apparatus is disclosed for practicing a method of treating viruses in the nasal mucosa. Vapor is generated, heated and delivered to the nasal mucosa in intermittent bursts, timed to coincide with inhalation. Control circuits are provided to maintain the temperature of the vapor at the point of delivery at a level greater than that necessary to kill viruses in the nasal mucosa. Timing circuits can synchronize the vapor delivery with a breathing cycle with heated vapor being supplied during inhalation and blocked during exhalation. Other circuits terminate operation when liquid is insufficient or after a predetermined timed interval.

Abstract: A device for controlling the breathing gas flow is provided including a breathing gas block (2), a cover (4) and a valve plate (3) as well as a heating device. Condensation effects are prevented from occurring with the supply of the smallest possible amount of energy by provision of a heating foil (16) as a heating element.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anaesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: A disposable aerosol generator for use with an inhaler device which includes a heater adapted to volatilize fluid stored in the disposable aerosol generator and method of using the inhaler. The disposable body includes a sealed chamber and an outlet, the chamber being located between first and second layers of material. The chamber holds a predetermined volume of a fluid which is expelled through the outlet when the fluid in the chamber is volatilized by the heater. The disposable body can include a series of spaced apart aerosol generators, each of which can be advanced to a release position at which the heater can heat one of the fluid containing chambers. Prior to heating the fluid, the outlet can be formed by severing the first and/or second layer with a piercing element and the volatilized fluid can be expelled from the outlet into a passage of a dispensing member.

Abstract: A breathing circuit component includes an inlet, an outlet and an enclosing wall. The enclosing wall defines a gases passageway between the inlet and the outlet. At least a region of the enclosing wall is formed from a breathable material that allows the passage of water vapor without allowing the passage of liquid water or respiratory gases. The breathing circuit component may be the expiratory limb of a breathing circuit.

Abstract: A humidifier and humidity sensor is disclosed for use with a breathing assistance apparatus. The humidity sensor preferably includes means to sense absolute humidity, relative humidity and/or temperature at both the patient end and humidifier end. The humidifier may also include provision to both control independently the humidity and temperature of the gases. Further, a chamber manifold is disclosed to facilitate easy connection of the humidifier to various outlets, inlets and sensors. A heated conduit is described which provides a more effective temperature profile along its length.

Abstract: A humidification device (10) for use with a CPAP unit (18) or similar breathing device is provided which includes a stationary cabinet (12) with a slide-type drawer member (14) adapted to hold a supply of humidifying water. The cabinet (12) includes an input (28) and an output (30) allowing connection of CPAP device conduits (100, 102) respectively for delivering air to the humidifying device (10), and for delivering humidified output air to a patient. Use of the sliding drawer member (14) facilitates filling of the device (10) with water and periodic cleanup thereof. In alternate embodiments, electrical resistance heaters (84, 86) are secured to the drawer member (14). Mating electrical connectors (42, 94) respectively mounted on the cabinet (12) and drawer member (14) provide electrical power to the heaters for water heating purposes.

Abstract: A humidifier is provided including a first humidifier part, a second humidifier part connectable with the first humidifier part, and a sealing gasket disposed between the first and second humidifier parts. The second humidifier part is configured to hold a volume of liquid therein and the first and second humidifier parts and the sealing gasket define first and second internal passages within the humidifier. The first passage is disposed so as to be exposed to a surface of the volume of liquid and the second passage is isolated from at least one of the first passage and the surface of the volume of liquid. The second passage is configured to communicate with a pressure and/or sound sensing device.

Abstract: A humidifier apparatus for operating at an air pressure is disclosed for use with a respiratory therapy breathing apparatus that provides a breathable gas supply to patients requiring higher concentrations of liquid vapor and gas pressure. The humidifier apparatus includes a feed liquid supply bag in fluid communication with a humidifier cartridge via a conduit. The conduit enables air to flow therethrough to equalize air pressure between the humidifier cartridge and the feed liquid supply bag in response to liquid being supplied to the humidifier cartridge.

Abstract: An aerosol generator includes a fluid passage arranged between a first and a second layer wherein the first and second layers at least partially define the fluid passage. A liquid supply is arranged to provide a fluid in liquid phase to the fluid passage. The aerosol generator also includes a heater arranged to volatilize the fluid in the fluid passage. An outlet of the aerosol generator is arranged to receive the volatilized fluid and direct the volatilized fluid out of the fluid passage. The aerosol generator can be used to generate aerosols containing medicated materials.

Abstract: An aerosol generator includes a housing, a heater and a mouthpiece wherein the heater volatilizes liquid material within a flow passage and forms an aerosol in the mouthpiece. Mixing ambient air with the vaporized liquid material controls a droplet size of the aerosol. The ambient air can be directed into the mouthpiece by at least one air passageway in an airflow entrainment control member. The at least one air passageway provides a desired volume and/or velocity of ambient air entering into the mouthpiece thereby achieving a desired droplet size distribution of an aerosol. In an alternative arrangement, a funnel shaped airflow entrainment control member includes a narrow end proximate the outlet end of the flow passage. A cone angle of the funnel-shaped member can be selected to provide a desired volume of ambient air which mixes with the vaporized liquid material and achieves a desired aerosol droplet size distribution.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anaesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: An aerosol is formed by supplying a material in liquid form to a flow passage and heating the flow passage such that the material volatizes and expands out of an open end of the flow passage. The volatized material combines with ambient air such that volatized material condenses to form the aerosol. An apparatus and method for generating such an aerosol are disclosed wherein the apparatus may include an electrically conductive sleeve at an open end of the flow passage, an electrically conductive flow passage and/or a spacer chamber. The volatilized material may contain a volatilized solute and vehicle such that the resulting aerosol particle sizes of the solute and the vehicle are either different or the same.

Abstract: An aerosol generator includes a heater arrangement having multiple heating sections and corresponding flow paths for volatilization of a fluid in liquid form. The flow paths can include first and second flow paths which are parallel to each other and sized such that the first flow path is smaller than the second flow path. During delivery of liquid to the flow paths, a smaller amount of vaporized liquid can be ejected from the first flow path, and the bulk of the vaporized liquid can be ejected from the second flow path.

Abstract: An aerosol generator such as a hand-held inhaler and method of delivering aerosol to a user inhaling on an outlet of a mouthpiece when a pressure drop is detected within the mouthpiece. A medicated fluid passing through a capillary passage is heated sufficiently to vaporize the fluid and form the aerosol by condensation of the vaporized fluid as it admixes with air. Air is supplied to the mouthpiece through an air passage which is initially closed during detection of the pressure drop. A metering chamber allows consistent delivery of precise doses of fluid to the capillary passage. The pressure drop is detected before air is supplied to the mouthpiece with the result that the aerosol can be quickly delivered to the user as the user begins to inhale on the mouthpiece. The quick delivery of aerosol provides more efficient use of the user's lung capacity.

Abstract: An inhaler that uses capillary effects to output droplets of pharmaceutical product is described. The inhaler includes transducers and lenses to generate focused acoustic waves. The frequency and pulse width output of the transducers are set to cause capillary action in a reservoir of pharmaceutical product. The capillary action results in the ejection of small droplets of pharmaceutical product at low frequencies.

Abstract: A fault protection circuit for a respiratory conduit heater element in a respirator humidification system is disclosed. The circuit includes a spark detector as well as overcurrent detector. Several variations are included for the spark detector including a two winding transformer, a center tapped two winding transformer), and a high pass filtered inductor. A semiconductor switching configuration is also disclosed. Once the protection circuit detects a change in current over a certain level, or the average level raises above a threshold, then the current in the heater element is interrupted for a preset period.

Abstract: A liquid composition to be vaporized for inhibiting an increase in blood sugar level which is prepared by dissolving or dispersing a concentrate of a hot water extract or alcohol extract of leaves of Lagerstroemia Speciosa, Linn. or Pers. as an active ingredient in an aqueous medium, a vaporizer for vaporizing the concentrate from a container containing the liquid composition by heating or nebulization and scattering it into the air, and a method of inhibiting an increase in blood sugar level by causing the vaporized active ingredient to be absorbed through the respiratory passage.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anaesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: A humidification unit adapted to be disposed in a patient circuit for humidifying the flow of breathing gas delivered to the patient via the patient circuit by an artificial ventilator system. The humidification unit includes an exothermic member having an outer surface and a plurality of hollow fibers disposed on the outer surface of the exothermic member. Each hollow fiber is defined by a peripheral wall having minute openings large enough to allow a gas to pass therethrough yet small enough to prevent a liquid from passing therethrough. Liquid delivered to the hollow fibers is heated by the exothermic member and the gas vapor resulting from the heating passes through the hollow fiber walls and humidifies the flow of breathing gas delivered to the patient.

Abstract: A fault protection circuit for a respiratory conduit heater element in a respirator humidification system is disclosed. The circuit includes a spark detector as well as overcurrent detector. Several variations are included for the spark detector including a two winding transformer, a centre tapped two winding transformer), and a high pass filtered inductor. A semiconductor switching configuration is also disclosed. Once the protection circuit detects a change in current over a certain level, or the average level raises above a threshold, then the current in the heater element is interrupted for a preset period.

Abstract: A breathing support system comprises a housing, a plate with a central aperture forming an annular bearing surface and with peripheral air passageways and a cap with a base and a wall slidably extending into the distal region. Air ports have a tubular guide extending proximally from the base. A valve assembly includes a disc formed with a periphery selectively positionable in contact with the bearing surface and passageways and also includes a thin rod with a distal end adjustably received within the guide. A resilient member is positioned between the base and plate urging the base and cap distally and the disc into contact with the bearing surface and passageways. An exhaust valve adapted to allow the exhaling of air is located on an upper radial extent of an intermediate region of the housing. A primary port is adapted to receive and support a bottle of primary medication.

Abstract: A breathing tube for humidified gases ventilation system has an internal conduit and a surrounding conduit within which the internal conduit is disposed. A connector at one end of the internal conduit and the surrounding conduit has an inhalation gases port for connection to an inhalation gases supply port of a ventilator. A gases flow path leads from the inhalation gases port to the space between the internal conduit and the surrounding conduit. A spirally wound heater wire may be disposed between the internal conduit and the surrounding conduit with turns of the spirally wound wire passing around the internal conduit.

Abstract: An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler.

Abstract: A disposable active humidifier for the mechanical ventilation of a patient, which has the particularity that it comprises a cartridge which forms a humidification chamber which is delimited by an inlet and by an outlet and can be interposed in the ventilation circuit. The cartridge has an interspace which is externally delimited by a heat exchange surface and is internally delimited by a hydrophobic membrane which surrounds the humidification chamber. A humidification fluid, originating from a bottle or bag, can be introduced in the interspace.

Abstract: An apparatus for increasing the humidification of the air stream breathed by a patient, having a tubular body that can be coupled to a heat and moisture exchange filter and forms a channel for the passage of an air stream. At least one portion of the channel is provided by a membrane impermeable to gases and permeable to ions and molecules with a partial charge. The membrane delimits an interspace that is external to the channel and allows passage of a water vapor flow.

Abstract: A heating device has a microwave source and a radiating antenna for coupling microwaves from the source into respiration gas in a gas flow-path of a patient breathing circuit, such as in an expiration gas-flow section internally located in a mechanical breathing aid. The microwave source and antenna are arranged to couple microwave energy sufficient to heat respiration gas in the flow path at a location at or upstream of a measuring device, such as a flow meter, to prevent condensation at the device. A detector and signal processor also are provided to calculate a moisture content from the microwave interaction with the respiration gas.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anaesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: A humidification unit adapted to be disposed in a patient circuit for humidifying the flow of breathing gas delivered to the patient via the patient circuit by an artificial ventilator system. The humidification unit includes an exothermic member having an outer surface and a plurality of hollow fibers disposed on the outer surface of the exothermic member. Each hollow fiber is defined by a peripheral wall having minute openings large enough to allow a gas to pass therethrough yet small enough to prevent a liquid from passing therethrough. Liquid delivered to the hollow fibers is heated by the exothermic member and the as vapor resulting from the heating passes through the hollow fiber walls and humidifies the flow of breathing gas delivered to the patient.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anaesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: A conduit for a breathing circuit includes a heater associated, at least in part, with a portion of hydrophilic material. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic material. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low-points in the conduit where condensation may collect.

Abstract: A breathing circuit component includes an inlet, an outlet and an enclosing wall. The enclosing wall defines a gases passageway between the inlet and the outlet. At least a region of the enclosing wall is formed from a breathable material that allows the passage of water vapor without allowing the passage of liquid water or respiratory gases. The breathing circuit component may be the expiratory limb of a breathing circuit.

Abstract: A humidifier and humidity sensor is disclosed for use with a breathing assistance apparatus. The humidity sensor preferably includes means to sense absolute humidity, relative humidity and/or temperature at both the patient end and humidifier end. The humidifier may also include provision to both control independently the humidity and temperature of the gases. Further, a chamber manifold is disclosed to facilitate easy connection of the humidifier to various outlets, inlets and sensors. A heated conduit is described which provides a more effective temperature profile along its length.

Abstract: A device for the controlled inhalation of therapeutic aerosols comprises means providing individual patient parameters and/or aerosol parameters for the inhalation. The aerosol doses, such as the tidal volume and the respiratory flow, are individually adjusted on the basis of these individual parameters. Thus, the inhalation device may be individually adjusted to the patient to be treated.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: An aerosol generator includes a tube having a first and a second end, a heater arranged relative to the tube for heating the tube, a source of material to be volatilized, the second end of the tube being in communication with the source of material, a valve operatively located between the source of material and the tube, the valve being openable and closeable to open and close communication between the source of material and the first end of the tube, and a pressurization arrangement for causing material in the source of material to be introduced into the tube from the source of material when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A method of making and a method of using an aerosol generator are also disclosed.