Abstract: A system and method for manipulating devices, such as a medical implant arranged within a subject, is provided. For non-invasive manipulation of a medical implant, a subject having a non-ferromagnetic medical implant arranged therein is arranged within a system having a static magnetic field and a plurality of adjustable magnetic fields. The non-ferromagnetic medical implant includes at least one cavity and at least one ferromagnetic or ferrimagnetic material arranged within the at least one cavity. The plurality of adjustable magnetic fields of the system are controlled to induce forces on the at least one ferromagnetic or ferrimagnetic material arranged within the at least one cavity to thereby apply the induced forces to the non-ferromagnetic medical implant to effectuate a non-invasive, in vivo manipulation of the non-ferromagnetic medical implant. Other implementations include the manipulation devices such as robotic medical systems, using magnetic fields to drive the robotic medical system.

Abstract: A vessel filter comprising a first region and a second region wherein the filter is movable between a collapsed position for delivery to the vessel and an expanded position for placement within the vessel. A first region has a filter portion having a converging region to direct particles toward the center of the filter and having a plurality of spaced apart elongated struts and, a plurality of connecting struts extending at an angle from the elongated struts to form closed geometric shapes. The second region is flared in the expanded position to have a transverse dimension increasing toward a second end portion opposite the first end portion. The second region includes vessel engaging hooks at the second end portion. The first region has a plurality of closed looped spacer struts extending radially with respect to a longitudinal axis of the filter when the filter is in the expanded position.

Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.

Abstract: Methods for correcting inaccurate translation of words or phrases in a mobile app, by users of that mobile app, in which those users can invoke an alternate “correction” function in the mobile app. The correction function allows users of the mobile app to send messages back to a programmer of the mobile app, including alternative translations, comments on translations, connotations of those translations, and other meaning associated with those translations. Edits made by users can be counted, or otherwise statistically measured, to determine a most-popular translation associated with the original text from the mobile app.

Abstract: The present disclosure relates to a ferromagnetic substance containing a crystal of a metal complex molecule in which a heterocycle is bonded to metal, the metal of the metal complex molecule is bonded to the metal of another metal complex via oxygen as a electron donor, and the ferromagnetic substance has a ferromagnetic property balanced with stability of crystals based on a metal-electron donor-metal bond angle that is from 130° to 160°. The present disclosure also relates to a drug containing, as a principal component, the crystal of the metal complex molecule.

Abstract: Methods for breast reconstruction and augmentation are provided which may reduce the incidence of capsular contracture. Methods for treating an encapsulated breast and reducing potential for capsular contracture in the breast are also provided.

Abstract: A catheter configured for use with a magnetic field-based localization system includes a distributed location sensor that includes a plurality of individual location sensing coils electrically connected in series. The distributed location sensor has an effective magnetic center based on the individual characteristics of each location sensing coil. The effective magnetic center can be located in a space occupied by another structure such as an irrigation fluid delivery tube. The plurality of individual location sensing coils are generally smaller, thereby easing placement, and collectively, when connected in series, output a relatively strong and noise-free signal.

Abstract: The present application describes an implant system useable for positioning an implant device such as a device useful for restricting passage of ingested food into the stomach. In one embodiment, the disclosed system includes a plurality of anchors that may be coupled to tissue within the stomach, or to a tissue tunnel formed by plicating stomach wall tissue. The anchor includes a loop. During use, the implant device is inserted through the loop and expanded such that it retains its position within the loop until removed. Instruments for implanting and explanting the implant device are also described.

Abstract: A roll-detecting sensor assembly includes a coil extending along and disposed about an axis. The coil comprises one or more portions, with each portion defining a winding angle. At least one of the portions defines a winding angle that is substantially nonzero relative to a line perpendicular to the axis, whereby the projected area of the coil in an applied magnetic field changes as the coil rotates about the axis. As a result, the coil is configured to produce a signal responsive to the magnetic field indicative of the roll of the sensor about the axis. In an embodiment, at least one of the portions defines a winding angle that is at least 2 degrees. In an embodiment, at least one of the portions defines a winding angle that is about 45 degrees.

Abstract: Gastrointestinal screening includes disposing a self-contained electronic capsule in a gastrointestinal tract. The electronic capsule is adapted to acquire data that is responsive to one or more physical conditions in the gastrointestinal tract and to compare the acquired data with stored threshold data to generate a discrete output relating to the condition of the gastrointestinal tract.

Abstract: A blood filter delivery system for delivering a filter into a vein includes an introducer and a push rod with a spline member disposed along the push rod. The spline member has a main body, and first and second boss portions spaced apart along the longitudinal axis to provide a gap for retaining anchor member of the filter during delivery via the introducer.

Abstract: Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Kits for use of illustrative tools are also shown. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation.

Abstract: This invention relates to a tissue expander for use in medical, veterinary and dental applications. The tissue expander comprises a self-inflating polymer network and a biodegradable polymer having a non-degraded state and a degraded state which in the non-degraded state constrains the inflation of the self-inflating polymer network and in the degraded state allows inflation of the self-inflating polymer network. In a preferred embodiment, the self-inflating polymer network and the biodegradable polymer form an interpenetrating polymer network or a semi-interpenetrating polymer network. Alternatively or in addition, the self-inflating polymer network forms a core and the biodegradable polymer forms coating which partially or fully surrounds the core.

Abstract: A medical device configured for diagnosis or treatment of tissues within a body is provided. The device includes an elongate, deformable member configured to be received within a lumen in the body and having proximal and distal ends. A position sensor is disposed at the distal end. In one embodiment, a conductor is wound about the member. The conductor is connected to the position sensor and has a first winding pitch over a first portion of the deformable member and a second winding pitch, different from the first winding pitch, over a second portion of the deformable member. In another embodiment, the member defines a neutral longitudinal axis extending between the proximal and distal ends. A conductor extending between the proximal and distal ends is connected to the position sensor at a connection node on the neutral axis.

Abstract: A method and system for cooling an internal space are provided. A laminate of a hydrophobic membrane and a hydrophilic membrane includes a superabsorbent polymer disposed on or encompassing the hydrophilic membrane. The superabsorbent polymer increases the wicking capacity of the hydrophilic membrane so that water from a source is distributed more rapidly across the hydrophilic membrane. The distributed water is evaporated from the hydrophilic membrane, causing evaporative cooling of the laminate and surrounding air stream(s). The cooled air stream(s) are used to cool the internal space.

Abstract: Intragastric balloon devices and methods for performing percutaneous gastronomy in the stomach of a patient are disclosed. The intragastric balloon device can include a support catheter, a main balloon member for use in reducing the functional gastric capacity of the patient's stomach, a support balloon member for anchoring the intragastric balloon device to the gastric wall of the patient, and an inflation mechanism for use in selectively inflating the main and support balloon members. In certain embodiments, an optional insertion device can be provided to facilitate percutaneous insertion and implantation of the intragastric balloon device within the patient.

Abstract: An intravascular filter assembly has an expanded state for capturing thrombi in a patient's blood vessel and a collapsed state for removal from the patient's blood vessel. The filter assembly includes a fixed hub defining a tubular portion, a plurality of struts extending from a first axial side of the tubular portion of the fixed hub, and an axially movable hub. The struts have an expanded configuration and a collapsed configuration. The axially movable hub has a first position radially surrounding at least an axial portion of the tubular portion and a second position axially spaced apart from the fixed hub along the struts. The struts are in the collapsed configuration when the movable hub is in the second position. A first coupling member extends from the first axial side from the movable hub; and a second coupling member extends from a second axial side opposite the first axial side.

Abstract: A surgical instrument can include a body, a tracking device, and a handle. The body can include proximal and distal ends, and a flow passage extending therebetween. The body can be formed from a malleable material such that it can be bent between the proximal and distal ends from a first configuration to a second bent configuration and maintain the bent configuration. The tracking device can be positioned adjacent the distal end for tracking a distal tip of the instrument. The handle can be coupled to the proximal end of the body and can include an internal flow passage in fluid communication with the body flow passage. The tracking device can include a pair of lead wires wound around the body to the handle, where the wound wires can conform to the bent configuration of the body such that they do not strain or break during bending of the body.

Abstract: A medical scope attachment device and system includes one or more expandable rings, each having a resilient main body and an inside diameter defining a central opening that corresponds to a dimension of a medical scope. One or more sets of opposing magnetic elements are disposed within each of the rings. The system also includes a ring attachment device having a shelf that is interposed between a pair of opposing electromagnets. The ring attachment device functioning to transition the expandable rings between an expanded and non-expanded state to receive an existing medical scope.

Abstract: The invention relates to a permanent percutaneous electric connection device intended to be fixed in an osseous structure of a patient to electrically connect an internal entity (150) located inside the body of the patient to an entity external to said body. The device encloses electric connection means running from a first connector to be connected to the external entity to a second connector to be connected to the internal entity. The device has an extension member (120) extending from a socket of the first connector. The extension member is designed for full osseous burial into the osseous structure with its free end (121) being substantially flush with the surface of said osseous structure. The device also comprises an electric connection member (130) comprising the second connector securely fastened to the free end of the extension member (120).

Abstract: A method and toolset capable of remotely moving a rotor of an implanted device in a first arcuate direction and detecting a first limit of travel, moving the rotor in a second, opposite direction and detecting a second limit of travel without altering the current performance setting of the implanted device, comparing the first and second limits of travel with known values for a plurality of selectable performance settings, and indicating the current performance setting of the implanted device.

Abstract: A vena cava filter is described, having one or more frame members or an elongated member arranged in helical fashion. A plurality of filaments connect frame members or portions of the elongated member. The filaments may be made of suture material. Hooks may be placed on a free end of the filaments, along the length thereof, or on one or more frame members to engage the blood vessel wall and anchor the filter. A retrieval member may be positioned on the filter to facilitate withdrawal of the filter from the blood vessel.

Abstract: A magnetically guided endoscopy capsule is separated from the surface of water with the aim of immersing the capsule completely in water, using the least possible magnetic force. A brief force curve (F_mag(t)) is thereby automatically generated on the capsule by a solenoid system, by one or more force pulses. Assuming that the capsule floats on the water surface at the start of the force curve, a force curve is applied generating an odd number of force pulses having a step profile. Each odd force pulse brings about at least a partial immersion of the endoscopy capsule in the liquid, and each even force pulse bring about at least a partial emersion of the endoscopy capsule out of the liquid.

Abstract: Methods and apparatus track surgical objects placed in a body cavity so that they may be reliably located and recovered from the body cavity at a later time. In one preferred embodiment, an apparatus comprises a vibrantly colored stringer threaded through apertures in a plurality of surgical objects and vibrantly colored tracking tags affixed to each end of the vibrantly colored stringer to maintain the surgical objects on the vibrantly colored stringer. In alternate embodiments, photo-reactive pigments in the range of 345-375 nm are also added to the vibrantly colored stringer and vibrantly colored tracking tags to enhance their visual detection under ambient lighting, when illuminated with a spectrum specific light source, and/or viewed through a spectrum-specific transmission filter in the same range of wavelengths.

Abstract: The present invention relates to a model based positioning system that includes a positioning device having at least one transmitter configured to be in a tracking environment, e.g. inserted into a body, a receiver having a plurality of receiver elements arranged outside the tracking environment, a control unit configured to measure amplitude and/or phase information of a signal transmitted from the at least one transmitter and received at each receiving element, and a memory unit M for storing a model for each receiving element. The control unit is also configured to estimate the position P of the positioning device by comparing the model for each receiving element with the measured received signal for each receiving element.

Abstract: The present invention relates to a magnetic system for attaching and removing medical devices and prostheses on human skin comprising external disks 4 and silicone implants 5; said system can increase, decrease or eliminate the magnetic attraction or repulsion force as a function of the rotation of the external disks 4 in relation to the silicone implants 5 such that the skin between the external disks 4 and the silicone implants 5 is subject to a pressure compatible with viable capillary microcirculation.

Abstract: A vaginal insert device including a support portion, a stabilizing portion, a removal device, and at least one fluid passageway extending though the support portion is disclosed. The vaginal insert relaxes in the vagina to deliver outward compression force against the bladder neck via the anterior vaginal wall to assist prevention of urinary stress incontinence. The substantially cylindrical support portion has a distal end, a proximal end, and a hollow interior section with a plurality of struts extending from the distal end to the proximal end. Desirably, the plurality of struts helically curve as the plurality of struts extend from the distal end to the proximal end. The largest circumference of the support portion has an insertion diameter when the plurality of struts are twisted together and an in-use diameter wherein the plurality of struts are extended outward into a convex position larger than the insertion diameter.

Abstract: Effective systems and methods for improving neural communication impairment of a vertebrate being and affecting motor activity of a peripheral body part including a first signal-providing component configured to provide pulsed peripheral stimulation signals at the peripheral body part, a second signal-providing component configured to provide a pulsed motor cortex stimulation signal to a motor cortex area, a substantially DC signal-providing component configured to provide direct current spinal stimulation signal at a neural spinal junction and a controller component configured to control timing of the pulsed peripheral stimulation signals and the pulsed motor cortex stimulation signal.

Abstract: The present invention provides a metal-salen complex compound having a controlled grain size that enables the metal-salen complex compound to exert its pharmacological effects as a medicine, at a target region. This metal-salen complex compound is composed of the following that has a crystal grain size of 8 ?m or less, and that is represented by the chemical formula below. N,N?-Bis(salicylidene)ethylenediamine metal M is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd.

Abstract: An apparatus comprises a controller for remotely controlling an implantable device that is used to adjust a gastric band, and the controller transmits a telemetric signal to the implantable device. The apparatus further comprises a table that provides support for the controller. A rail is oriented in a first direction with respect to the table, and a tray is slidably coupled to the rail. The tray receives the controller, and the rail moves the tray and the controller in the first direction with respect to the table. The apparatus further comprises a roller coupled to the rail. The roller aids in moving the rail, the tray, and the controller in a second direction with respect to the table. The apparatus further comprises an attachment mechanism for securing the controller to the tray. The apparatus locates the controller in a desired location with respect to a patient.

Abstract: The position of an antenna incorporated in a capsule-type endoscope 3 that moves in a body is estimated using a plurality of antennae, and where the distance dij between two positions Pti and P(t?1)j estimated at adjacent times falls within a predetermined value, pieces of information for these positions are related to each other and stored in a memory as connection information. Subsequently, processing for searching for a route from the connection information stored in the memory and calculating a track is performed.

Abstract: An apparatus for locating an embedded passive integrated transponder (PIT) tag is provided. An embodiment of the locating apparatus includes a resonator capable of electromagnetically coupling to the PIT tag, and a feedback circuit connected to the resonator and configured to monitor a load conductance of the resonator. A distance between the resonator and the PIT tag is indicated by a change in the monitored load conductance when the resonator and the PIT tag are electromagnetically coupled. Another embodiment includes a resonator capable of stimulating a response signal from a PIT tag, and a processing circuit capable of calculating the distance between the resonator and the PIT tag based on the amplitude of the response signal.

Abstract: A magnetically guiding system includes: a capsule medical device that has a magnet provided therein; an information acquiring unit that acquires physical information about magnetic guiding of the capsule medical device; a magnetic field generating unit that generates a magnetic field for magnetically guiding the capsule medical device; and a control unit that sets a magnetic field condition based on the physical information acquired by the information acquiring unit and controls the magnetic field generating unit to generate a magnetic field corresponding to the magnetic field condition.

Abstract: A method for displaying a position of a medical device, such as a catheter, during insertion thereof into a patient. In one example embodiment, the method includes obtaining a first set of detected position data relating to a location marker, such as a permanent magnet, then determining a possible first position thereof. A first confidence level relating to a match between the first set of detected position data and a first set of predicted position data is assigned. A determination is made whether the first confidence level meets or exceeds a first threshold. If the first confidence level meets or exceeds the first threshold, a determination is then made whether the first position of the location marker is within a first detection zone. If the first position of the location marker is within the first detection zone, the first position of the location marker is displayed.

Abstract: An implantable device includes at least one solid structure having an external surface and a volume beneath the surface. One or more of a first conductor or set of conductors is disposed externally and/or internally on or within the structure and an array of elongate electrically conductive elements are disposed radially outwardly within the volume. A breach is detected when a conductive fluid intrudes into the volume through the surface.

Abstract: An electrical system having an underlying structure resembling the double helix most commonly associated with DNA is used to produce useful electromagnetic fields for health applications and/or medical applications.

Abstract: Methods, devices and systems for Transcranial Magnetic Stimulation (TMS) are provided for synchronous, asynchronous, or independent triggering the firing multiple of electromagnets from either a single power source or multiple energy sources. These methods are particularly useful for stimulation of deep (e.g., sub-cortical) brain regions, or for stimulation of multiple brain regions, since controlled magnetic pulses reaching the deep target location may combine to form a patterned pulse train that activates the desired volume of target tissue. Furthermore, the methods, devices and systems described herein may be used to control the rate of firing of action potentials in one or more brain regions, such as slow or fast rate rTMS. For example, described herein are multiple electromagnetic stimulation sources, each of which are activated independently to create a cumulative effect at the intersections of the electromagnetic stimulation trajectories, typically by means of a computerized calculation.

Abstract: A medical article is used to repair prolapses of various pelvic organs including vaginal vault prolapse. The medical article can include a first flap comprising a dual density mesh formed of a first and second filament, a second flap comprising a single density mesh formed of the first filament, and a third flap comprising a single density mesh formed of the second filament. The first, second, and third flap can share a common intersection that can form an arc. The medical article can be formed by knitting a uniform piece of mesh and the arc can be configured to conform to a surface of a pelvic organ. Methods of manufacturing and methods of using the medical article are also disclosed.

Abstract: Disclosed herein is a sleep aid device including: an electrode arranged on the surface of a pillow in such a manner as to come into contact with the scalp of a user; a brain wave signal acquisition section adapted to acquire a brain wave signal of the user via the electrode; an analysis section adapted to analyze the acquired brain wave signal; and a control section adapted to control the execution of a preset process according to the sleep stage representing the depth of sleep of the user identified by the analysis result.

Abstract: A method and apparatus for magnetically levitating and further steering of an intraluminal device, such as a swallowable microelectronic capsule, for monitoring bodily functions is provided. The method comprises diamagnetically-stabilized levitation, followed by dynamic modification of the external magnetic field producing the said levitation, so that the levitating intraluminal device can be steered in desired direction. The said intraluminal device contains appropriate sensors and reports in real time the forces and pressures exerted on it, as well as its position, so that the levitation and the steering can be dynamically adjusted using appropriate dynamic control of external magnetic devices such as solenoids.

Abstract: A transponder string comprising multiple transponders is configured for injection into human tissue. In one embodiment, the transponders are sized to move through a needle for injection into the human tissue. Positions of the transponders with reference to one another may be maintained by coupling the transponders via a filament, adhesive backed substrate, shrink tubing, and/or any other suitable substrate. The transponders are configured to transmit data to a mobile computing device, e.g., a wand, smart phone or wireless tablet positioned outside the human tissue such that positions of the transponders are determinable, e.g., during an excision surgery.

Abstract: A device for loading and customizing brachytherapy carriers based on the principles of optimizing a more precise and predictable dosimetry, and adaptable to the geometric challenges of a tumor bed in a real-time setting. The present invention relates to a specialized loading device designed to enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently.

Abstract: The disclosed system and method are directed to qualifying an image(s) and exposing an individual to the qualified image(s) for the purpose of eliciting a relaxation response. More specifically, a sequential rendition of qualified images are presented to either a normal or cognitively impaired person in order to elicit relaxation and/or reduce agitation. Qualified images include those with both particular natural landscape content or elements (e.g., low vegetative growth, an open area, trees, a horizon, a visible sky, an absence of any man-made structures, and fresh water) and a particular average fractal dimension.

Abstract: The present invention relates to signaling mechanisms that transduce magnetic inputs into physiological cellular outputs. More particularly, the present invention relates to systems and methods for non-invasively controlling cellular signaling functions and behaviors by harnessing receptor-mediated and intracellular molecular-mediated signal transduction using nanomagnetic cellular switches.

Abstract: Described are pelvic implants and methods of surgically placing pelvic implants, that provide treatment for pelvic floor disorders by support of the levator. A pelvic implant (100, 102) may comprise a tissue support portion (104) to be placed in contact with tissue to be supported, extension portions (106, 110) that extend from the tissue support portion to provide additional support, and tissue fasteners (108, 112) to attach extension portions to supportive tissue.

Abstract: Sleep mask for reducing sleep inertia. In an embodiment, the sleep mask comprises a foam layer having a shape that covers both of a human subject's eyes so as to attenuate ambient light. Visual stimulation element(s), configured to emit light, are positioned between the foam layer and the subject's eyes. In addition, a plurality of sensors positioned on the forehead of the subject collect electroencephalogram (EEG), electrooculogram (EOG), and electromyogram (EMG) signals. A soft exterior cover houses the foam layer, the visual stimulation element(s), and the sensors. The sleep mask further comprises processor(s) that determine and record each sleep stage of the subject, determine when to wake the subject, and, when it is determined to wake the subject, control the visual stimulation element(s) to wake the subject using emitted light.

Abstract: An implantable device system is disclosed. The implantable device system comprises, a first energy transceiver system, a second energy transceiver system at least partially implanted within an organic tissue and capable of being interrogated by the first energy transceiver system, and a sensing system, wherein a state of the sensing system is available at the second energy transceiver system.

Abstract: A device and method for subcutaneously implanting an identification chip into a domestic animal, the identification chip becoming relatively immobile once implanted.

Abstract: An implantable device controls the movement of fluid to an inflatable portion of a gastric band. The implantable device includes a body. The body has an inlet, an outlet and a valve seat positioned between the inlet and the outlet. The body defines a fluid passage from the inlet to the outlet. The implantable device also includes a diaphragm. The diaphragm has one or more edges coupled to the body. The diaphragm is made of an elastomeric material and capable of being moved between a closed position that blocks the valve seat and does not allow the fluid to move from the inlet to the outlet and an open position that does not block the valve seat and allows the fluid to move from the inlet to the outlet.

Abstract: A volume of a patient can be mapped with a system operable to identify a plurality of locations and save a plurality of locations of a mapping instrument. The mapping instrument can include one or more electrodes that can sense a voltage that can be correlated to a three dimensional location of the electrode at the time of the sensing or measurement. Therefore, a map of a volume can be determined based upon the sensing of the plurality of points without the use of other imaging devices. An implantable medical device can then be navigated relative to the mapping data.