Abstract: Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use.

Abstract: A tobacco smoking mixture including an ammonia-release compound adapted to be formed into a lit-end cigarette is provided. The ammonia-release compound is incorporated in or on tobacco cut filler in an amount effective to reduce the cytotoxicity, and/or selective smoke constituents of cigarette smoke. Exemplary ammonia-release compounds include ammonium acetate, ammonium hydroxide, hexammine cobalt (III) chloride, hexammine cobalt (III) acetate, and combinations thereof. The ammonia-release compounds can release ammonia at temperatures between about 60° C. and about 400° C. Ammonia-release compounds can be combined with additives, such as glycerine, cobalt acetate, copper (II) acetate, zinc acetate, other metal salts or combinations thereof, to further reduce the cytotoxicity of cigarette smoke.

Abstract: A pre-portioned moist product comprising a portion of plant material and a coating is disclosed. Preferably, the plant material comprises tobacco. The coating includes a soluble, non-cross-linkable component and an cross-linkable component which becomes substantially water-insoluble upon crosslinking. The soluble component of the coating dissolves upon placement in the mouth, while the insoluble component disintegrates and/or loses structural integrity once the soluble component has dissolved to release and disperse the plant material in the user's mouth.

Abstract: The invention relates to a nicotine oral delivery product containing a powder enclosed in a water insoluble pouch, wherein said pouch is permeable for saliva and therein dissolved parts of the powder, wherein said powder comprising at least a) nicotine selected from the group consisting of tobacco, nicotine salts, nicotine base, stabilized nicotine, and mixtures thereof corresponding to 0.1 to 20 mg nicotine in the form of nicotine base and b) a chewing gum composition and a method of producing said nicotine oral delivery product.

Abstract: Oral tobacco products having a gel-coating and methods for making are provided. The method includes (a) molding a portion of tobacco material to form a pre-portioned piece of tobacco material, the tobacco material comprising moist smokeless tobacco; (b) contacting the pre-portioned piece of tobacco material with a gel-coating solution to form a gel-coating comprising at least one polymer on an outer surface of the pre-portioned piece of tobacco material to form a gel-coated oral tobacco product, said gel-coating comprising an inner surface disposed around the pre-portioned piece of tobacco material and an outer surface; and (c) forming one or more of perforations, uncoated areas and holes in the gel-coating of the oral tobacco product to form a gel-coated oral tobacco product.

Abstract: A bioactive dose for delivering a bioactive agent to a mammal, includes a solid bioactive dosage unit containing at least one bioactive agent and a rapid release coating provided on at least one outer surface of the solid bioactive dosage unit, the rapid release coating containing a material having a property of rapidly modulating a pH of bodily fluids in which the material comes in contact in a direction towards an ideal absorptive pH or towards an ideal pH to hinder absorption of the at least one bioactive agent given the pKa that least at one bioactive agent.

Abstract: Tobacco articles having tobacco disposed in a porous matrix. The tobacco articles can provide tobacco to an adult consumer in the form of particles, liquid, or vapor so as to furnish tobacco satisfaction to the consumer. The tobacco can be integrally molded with a plastic material so that at least a portion of the tobacco is disposed in pores of the matrix.

Abstract: A tobacco solution containing water; a polysorbate compound; and an effective serving of tobacco constituents for vaporizing the tobacco solution for inhalation. The tobacco constituents may include nicotine, monoamine oxidase inhibitor, tobacco flavor, and tobacco aroma derived from tobacco.

Abstract: The present invention relates to genetic constructs, which can be used in the preparation of transgenic plants. The constructs can have the ability of reducing nitrate concentration in the plant, in particular the plant's leaves, and for inducing a senescence-like phenotype. The invention extends to plant cells transformed with such constructs, and to the transgenic plants themselves. The invention also relates to methods of producing transgenic plants, and to methods of reducing nitrate content in plants. The invention also relates to harvested plant leaves, for example tobacco leaves, that have been transformed with the genetic constructs, and to various tobacco articles, such as smoking articles, comprising such harvested plant leaves.

Abstract: A method of preparing a whitened tobacco material is provided, the method including the steps of (i) extracting a tobacco material with an aqueous solution to give a tobacco pulp and a tobacco extract; (ii) treating the tobacco pulp with at least one of a caustic reagent and an oxidizing agent for a time and at a temperature sufficient to lighten the color of the tobacco pulp to give a whitened tobacco pulp; (iii) clarifying the tobacco extract to remove higher molecular weight components; and (iv) combining the whitened tobacco pulp with a clarified tobacco extract to form a whitened tobacco material. The whitened tobacco material can be isolated and incorporated into a smokeless tobacco product. The invention also provides a smokeless tobacco product incorporating a whitened tobacco material. The smokeless tobacco product may be a snus-type formulation contained within a sealed pouch.

Abstract: The invention provides a multi-layered smokeless tobacco product comprising two or more formulations with varying properties. In some embodiments, the smokeless tobacco products provide combinations of different organoleptic properties within the same product. In certain embodiment, these combinations allow for a modified release profile of active ingredients as the user enjoys the smokeless tobacco product. The invention further provides methods for making and using the smokeless tobacco product.

Abstract: Disclosed herein are genetically modified tobacco plants, and tobacco products derived from such plants, comprising an altered uptake and/or altered levels of at least one environmental contaminant or other non-natural chemical as compared to an unmodified parent tobacco plant from which the modified plant is derived. The alteration in uptake and/or levels may be a reduction, or alternatively an increase, in the uptake and/or levels of the environmental contaminant or other non-natural chemical. These methods and plants are useful for improving tobacco products or in generating tobacco lines that may have environmentally useful properties.

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-soluble polymer matrix, cellulosic fibers embedded in the mouth-soluble polymer matrix, and nicotine or a derivative thereof dispersed in the mouth-soluble polymer matrix. The oral product is adapted to release the nicotine or a derivative thereof from the body when the body is received within the oral cavity and exposed to saliva.

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, exhausted tobacco fibers embedded in the mouth-stable polymer matrix, and an additive dispersed in the mouth-stable polymer matrix. The oral product is adapted to release the additive from the body when the body is received within the oral cavity and exposed to saliva.

Abstract: An oral tobacco product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix and tobacco fibers embedded in the mouth-stable polymer matrix. The oral tobacco product can be formed by extruding a mixture of mouth-stable polymer and tobacco fibers.

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and nicotine or a derivative thereof dispersed in the mouth-stable polymer matrix. The oral product is adapted to release the nicotine or derivative thereof from the body when the body is received within the oral cavity and exposed to saliva.

Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.

Abstract: A pre-portioned moist product comprising a portion of plant material and a coating is disclosed. Preferably, the plant material comprises tobacco. The coating includes a soluble, non-cross-linkable component and an cross-linkable component which becomes substantially water-insoluble upon crosslinking. The soluble component of the coating dissolves upon placement in the mouth, while the insoluble component disintegrates and/or loses structural integrity once the soluble component has dissolved to release and disperse the plant material in the user's mouth.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: The invention provides a smokeless tobacco composition adapted for oral use, the composition including a tobacco material and an effervescent material. The effervescent material includes a sugar material containing an entrapped gaseous component, such that release of the entrapped gaseous component occurs upon dissolution of the sugar material in the oral cavity. The invention also provides a method for making a smokeless tobacco composition that involves mixing a tobacco material with an effervescent material, the mixing step including either admixing a granulated composition comprising a tobacco material with a gasified sugar material in particulate form, or forming a gasified sugar material in situ by mixing a water source with a molten composition comprising a tobacco material and a sugar alcohol.

Abstract: An oral pouched product comprising a pouch containing moist botanical beads comprising compacted loose, fibrous moist botanical material and method of manufacture thereof. The loose, fibrous moist botanical material can comprise moist smokeless tobacco. The pouch comprises a porous outer web, and the beads comprise a majority amount of loose, fibrous moist botanical material having a moisture content of at least about 50% OV.

Abstract: Methods for increasing the concentration of antioxidants during senescence and curing of tobacco leaves include application of a chemical solution. The methods include spraying the solution onto the tobacco plant prior to harvest and/or applying the chemical solution to the soil surrounding roots of growing tobacco plants. The application of the chemical solution preferably occurs between topping and harvest, and is optimized to simulate the production of antioxidants and interfere with the formation of TSNAs during curing. The tobacco can be burley tobacco subjected to air curing.

Abstract: A class of molecularly imprinted polymers that specifically recognizes and binds to TSNAs are useful, for example, in analysis and separation of TSNAs from biological fluids. Such polymers are also useful in methods of treating and manufacturing tobacco products and materials. Also disclosed are selectively adsorbent non-molecularly imprinted polymer of a non-acidic monomer and a cross-linker having polar functionality, one of which is hydrophilic, the other of which is hydrophobic, and the use of such polymers in the treatment of materials containing nicotine and nitrosamine.

Abstract: A process for treating a tobacco material comprising: (a) extracting a tobacco material with a solvent to produce a tobacco extract and a tobacco residue; (b) contacting the tobacco extract with an antioxidant; and (c) contacting the mixture of (b) with an antioxidant scavenger, to produce a treated tobacco extract. The treated tobacco extract is reapplied to the tobacco residue to form a treated tobacco material. In addition, a smoking composition, a smoking article and a smokeless tobacco oral delivery product contain the treated tobacco material.

Abstract: A tobacco product produced by wrapping cut tobacco with a pouch or a cigarette paper, wherein the pouch or the cigarette paper has an inner layer and an outer layer, and a paper of the outer layer has an air permeability higher than that of a paper of the inner layer.

Abstract: A novel cigar is provided with an elongated cigar puller device which extends into the interior of the cigar. By removing the cigar puller from the cigar, the tobacco fill material of the cigar is disrupted so as to improve the draw of the cigar. Once the cigar puller is removed from the tobacco fill material, a flavorant and/or aromatic can be infused into the less dense tobacco fill material which is provided upon the removal of the cigar puller.

Abstract: A method for producing triethyl citrate from one or more plants of genus Nicotiana is provided. The triethyl citrate can be derived inter alia from Nicotiana species biomass or from seed. In certain embodiments, the triethyl citrate is produced by condensation of ethanol, generated by fermentation of starting material derived from tobacco biomass or seed, and citric acid, also derived from tobacco biomass or seed. The invention also provides articles and compositions including tobacco articles and tobacco compositions that include triethyl citrate produced from one or more plants of genus Nicotiana.

Abstract: A package of smokeless tobacco includes a flavor patch located in the package to provide flavor to smokeless tobacco. Also disclosed is a method of packaging smokeless tobacco by combining a package with a flavor patch disposed inside the package, the flavor patch comprising a flavor and an adsorbent, so that the flavor patch resides in an interior of the package; and adding smokeless tobacco to the package with the flavor patch.

Abstract: A smoking article composition and a method of making a smoking article composition and an additive, wherein the additive comprises particles anchored to the cut filler by a metal oxide support. The additive can be formed by combining particles and a metal oxide precursor solution with the smoking article composition. The smoking article composition can comprise tobacco cut filler, cigarette paper and/or cigarette filter material.

Abstract: A method of providing a comestible plant material taken orally by coating a micronized plant material with a first layer of polysaccharides or proteins, then a second layer of polysaccharides or proteins is disclosed. A bi-encapsulated plant material produced by this process is also disclosed.

Abstract: A composition intended to be employed for therapeutic purposes incorporates an active ingredient (e.g., a source of nicotine) and at a non-active ingredient that is carried by a porous substrate. The non-active ingredient can be a substance that has the capability of affecting the pH of the biological system to which it is applied (e.g., basic substance and/or buffering agent is sorbed onto the porous carrier, so as to be in intimate contact with that carrier). Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) and nicotine polacrilex. The basic substance can be sodium carbonate, and the porous substrate can be microcrystalline cellulose. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and can be used as a nicotine replacement therapy.

Abstract: Provided is a tobacco-free oral flavor delivery pouch product that provides and engaging and flavorful experience to a user. The pouch product includes a porous pouch wrapper and an inner filling material. The inner filling material can include a non-tobacco, botanical component, at least one functional ingredient and a solid flavor component dispersed throughout the inner filling material. The pouch product delivers multiple textures to the user's mouth.

Abstract: A cigar comprises a mouth end; a tobacco section comprising tobacco material; at least one sweetener dispersed throughout the tobacco section; and/or a flavor potentiator and/or a taste modifier on an outer surface of the mouth end for enhancing the sweet taste of the cigar.

Abstract: The invention provides a smokeless tobacco product comprising a tobacco extract. In some embodiments, the smokeless tobacco product is translucent. The invention further provides methods for making and using the smokeless tobacco product. In certain embodiments, the smokeless tobacco product comprises isomalt, maltitol syrup, and a translucent tobacco extract prepared by ultrafiltration.

Abstract: A smokeless tobacco product is provided that includes a tobacco material in the form of a tobacco extract, a particulate tobacco material, or a combination thereof. In some embodiments, the smokeless tobacco product is substantially translucent. Methods for making and using the smokeless tobacco product are also provided. The smokeless tobacco product can include isomalt, maltitol syrup, particulate tobacco, and a translucent tobacco extract prepared by ultrafiltration.

Abstract: The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nomicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.

Abstract: A tobacco smoke filter which gives an acceptable vapor phase filtration and flavor delivery in the presence of a volatile flavorant (e.g. menthol), the filter containing activated carbon in which (1) pores of under 2 nm pore diameter (micropores) provide a pore volume of at most 0.3 cm3/g (NZ); and (2) (a) pores of 2 to 50 nm pore diameter (mesopores) provide a pore volume of at least 0.25 cm3/g (N2) and/or (b) pores of 7 to 50 nm diameter (larger mesopores) provide a pore volume of at least 0.12 cm3/g (Hg).

Abstract: The present invention discloses genetically modified tobacco plants, and tobacco products derived from such plants, comprising a decrease in at least one amino acid such that upon heating and/or burning, the tobacco plant or a portion thereof generates reduced levels of a compound derived from the at least one amino acid as compared to an unmodified parent tobacco plant or a portion thereof. In an embodiment, the tobacco generates reduced levels of acrylamide and/or acrylonitrile upon heating and/or burning of the tobacco as compared to an unmodified parent tobacco line. These plants are useful for improving tobacco products.

Abstract: Methods of preparing highly purified steviol glycosides, particularly Rebaudioside D, are described. The methods include purification from the extraction stage of the Stevia rebaudiana Bertoni plant, purification of steviol glycoside mixtures, Rebaudioside D and Rebaudioside A from a commercial Stevia extract, and purification of Rebaudioside D from remaining solutions obtained after isolation and purification of Rebaudioside A and a high purity mixture of steviol glycosides. The methods are useful for producing high purity Rebaudioside D, Rebaudioside A, and steviol glycoside mixtures. The high purity steviol glycosides are useful as non-caloric sweeteners in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

Abstract: Provided is a moist smokeless tobacco product including a hydrated membrane coating and a portion of tobacco material. Preferably, the tobacco material is pre-portioned and formed to include at least one dimple and/or at least one hole through the tobacco material so as to increase the surface area of the tobacco product.

Abstract: The invention relates to an aerosol-forming material for a hookah, which comprises a first substance and at least one second substance which is held by the first substance and which is at least partly released following activation of the aerosol-forming material, wherein the first substance comprises pores for receiving the second substance and the second substance is a fluid. Provision is made for the first substance, based on the weight thereof, to comprise at least 65 wt % of clinoptilolite.

Abstract: The present invention provides a polynucleotide having a function of regulating a content of a plant metabolite, a polypeptide having a function of regulating a content of a plant metabolite, a vector containing the polynucleotide or a part of the polynucleotide, and a transformed plant produced by using the vector, and a method for producing the transformed plant, and according to the above polynucleotide, polypeptide, vector, transformed plant and method, a novel gene regulating a content of a plant metabolite and use of the novel gene.

Abstract: Tobacco articles having tobacco disposed in a porous matrix. The tobacco articles can provide tobacco to an adult consumer in the form of particles, liquid, or vapor so as to furnish tobacco satisfaction to the consumer. The tobacco can be integrally molded with a plastic material so that at least a portion of the tobacco is disposed in pores of the matrix.

Abstract: Provided is a disintegrable or non-disintegrable oral flavor delivery product. The product includes a disintegrable or non-disintegrable chewable pouch with a plurality of perforations. The pouch encloses a non-tobacco flavor product that can be in a gel, semi-liquid, and/or liquid form. A user chews, sucks, and/or manipulates the pouch to cause the enclosed flavor product to leach out of the perforations into the user's mouth.

Abstract: An oral tobacco product (1) has a pouch (2) made from a nonwoven fabric sheet and containing tobacco particles made from tobacco materials, for being designed to be put in a user's mouth to allow the user to absorb active constituents of tobacco from the tobacco particles via saliva, and a piece of string (6) with a flavoring added, disposed inside the pouch (2).

Abstract: An oral tobacco product which includes a tobacco pouch obtained by wrapping tobacco particles made from a tobacco material in a wrapper, the tobacco pouch allowing a user to take in tobacco components of the tobacco particles via saliva, when put in the user's mouth, and an outer wrapper individually wrapping the tobacco pouch therein. The outer wrapper has liquid impermeability and is provided with a lug for the user.

Abstract: A tobacco product contains tobacco material enriched with anatabine or a salt or derivative thereof. In some aspects, the tobacco material has very low levels of tobacco specific nitrosamines (TSNA), such as having a collective content of N?-nitrosonornicotine (NNN), 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK), N?-nitrosoanatabine (NAT) and N?-nitrosoanabasine (NAB) which is about 0.3 ?g/g or less. The tobacco product may be a smoking product, such as cigarettes, cigars, or pipe tobacco; or a smokeless product, such as chewing tobacco, snuff, snus, tobacco-containing gum or lozenges, or a dissolvable powdered tobacco-based smokeless product.

Abstract: A tobacco production system is provided for producing useable tobacco material having chemical and physical properties acceptable to tobacco industry stakeholders, by growing tobacco entirely in a directly seeded system, under an intensive biomass growing system, mechanically harvesting above-ground portions of the plant a plurality of times during the growing season, curing tobacco leaves and stalks together, and processing the cured tobacco material to obtain cured leaf material suitable for use in tobacco products including, but not limited to, cigarettes, cigars, snus, snuff, chewing tobacco, pipe tobacco, reconstituted tobacco material, and other manufactured tobacco products.

Abstract: The invention relates to a smoking article incorporating a smoking material comprising three main components, namely a non-combustible inorganic filler, an alginic binder and aerosol generating means. The smoking material is combined with tobacco material, which may be treated with additional humectant, to provide a smoking article that has an aerosol transfer efficiency ratio of greater than 4.0.

Abstract: An oral pouched product comprising a pouch containing moist botanical beads comprising compacted loose, fibrous moist botanical material and method of manufacture thereof. The loose, fibrous moist botanical material can comprise moist smokeless tobacco. The pouch comprises a porous outer web, and the beads comprise a majority amount of loose, fibrous moist botanical material having a moisture content of at least about 50% OV.