Abstract: A medical seal dispenser having a container molded of plastic and having clamshell portions hinged together. The clamshell portions of the container can be locked together when in a closed position. One clamshell portion includes a core holder for holding a roll of medical seals. The core holder includes speed bumps that are raised or domed protrusions on the core holder to provide rolling friction to the roll of medical seals during dispensing. This controlled rotation of the roll prevents spooling if the carrier strip is pulled out of the container too quickly.

Abstract: The invention presents an apparatus and techniques for determining whether a medical electrode, such as a defibrillation electrode coupled to an automated external defibrillator, is in a condition for replacement. The determination can be made as a function of one or more data. In one exemplary embodiment, the determination is a function of one or more measurements of an impedance of a hydrogel bridge in a test module. In another exemplary embodiment, the determination is a function of one or more environmental condition data from one or more environmental sensors.

Abstract: A merchandise system for disposable absorbent articles is provided. The merchandise display system includes a first line-up and second line-up of disposable absorbent articles designed to match a wearer's stage of development. The system also includes various color schemes associated with the first and second line-ups in order to facilitate consumers' identification and selection of the appropriate absorbent article configuration for a particular wearer. A merchandise system for baby care articles is also provided.

Abstract: The present invention relates to a packaging system for airway devices that permits their rapid access. In particular, the packaging system is capable of maintaining the device in storage under sterile conditions, yet be capable of facilitating rapid unpackaging and use.

Abstract: Pharmaceutical compositions comprising 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile and pharmaceutically acceptable salts thereof are provided as well as kits and articles of manufacture comprising the pharmaceutical compositions as well as methods of using the pharmaceutical compositions.

Abstract: A pain management kit for the administration of medication and a related method of use is disclosed. The pain management kit includes the primary medical supplies for performing a continuous nerve block procedure, preferably in a single, sterile container. Specifically, the kit may contain medical supplies to create a sterile field, perform a local anesthetic procedure and to perform a continuous nerve block procedure. Preferably, the contents of the kit are arranged in the general order of their use.

Abstract: A container is provided for holding a chemical compound or mixture. Areas are provided on the surface of the container which allow for gaseous by-products from the chemical contained within the container to permeate from a chamber through the surface of the container. A septum is over-molded into the surface of the container. The septum is formed in such a manner that it provides a sealing effect to close an opening in the container.

Abstract: The present invention relates to mechanically hemostatic body-absorbable compositions having a putty-like consistency. The compositions preferably comprise a finely powdered, carboxylic acid salt and a liquid block copolymer of ethylene oxide and propylene oxide.

Abstract: A pharmaceutical low dose, antibiotic combination of two antibiotics selected from a carbapenem and an aminoglycoside, present as a single unit fixed low dose injection effective at very low concentrations. The antibiotic combination is suitable for the treatment of bacterial/multibacterial infections, and is particularly suitable for neonates, children, and other patients with low tolerance, and who are prone to serious fatal mixed multi-bacterial infectious diseases where potential toxicity due to higher doses is a cause for concern.

Abstract: A system of surgical instruments for use with at least a first implant and a second implant of the same type but different sizes is provided. The system includes a first container containing at least a first surgical instrument of a first type that is size specific and a second surgical instrument of a second type that is size specific; a second container containing at least a third surgical instrument of the first type and a fourth surgical instrument of the second type, wherein both the third and fourth instruments are of a second size that is different from the first size and that corresponds to the second implant; and a third container containing at least a fifth surgical instrument of a third type that is size independent.

Abstract: A surgical device comprising a first receptacle having a first mouth and a second receptacle having a second mouth, wherein the first mouth is in open communication with the second mouth via a joint joining the first receptacle with the second receptacle, and wherein the first mouth and second mouth open in a common direction. The surgical device can be used to effectively collect fluid during surgery in a first receptacle while simultaneously and independently retaining equipment and other medical supplies, such as tubes, wires, and/or tools, in a second receptacle. A drape sheet for covering at least a portion of a patient, the drape sheet optionally having a fenestration therein, with the surgical device being attached to the drape sheet.

Abstract: There is provided a powder composition for use in a pharmaceutical product, the composition including a) 5(S)-(2?-hydroxyethoxy)-20(S)-CPT; at least one cyclodextrin; wherein 5(S)-(2?-hydroxyethoxy)-20(S)-CPT includes less than 5% of 5(R)-(2?-hydroxyethoxy)-20(S)-CPT. Preferably, in the powder composition, 5(S)-(2?-hydroxyethoxy)-20(S)-CPT is substantially free from said 5(R)-(2?-hydroxyethoxy)-20(S)-CPT.

Abstract: The system according to the present disclosure includes a metal stent (3) as a medical implant for treating lesions in blood vessels and a packaging (1) having an inside volume, in which the stent (3) is arranged in a protected manner. The stent (3) has a plurality of webs (33), which produce a tubular shape with each other, and a proximal end (31) and a distal end (32), between which a stent lumen (34) extends. The stent surface (35) has a hydrophilic property. The molecular chemical impurities originating in the atmosphere, primarily hydrocarbon compounds, are significantly reduced on the surface by a treatment, whereby the contact angle as a measure of the hydrophilicity of a water drop present on the surface (35) is reduced in proportion to the contact angle prior to said treatment. The stent (3) is stored in an inert manner in the packaging (1).

Abstract: A compound of formula 1 and/or its salts, tautomers or solvates is used to treat hematological malignancies. In an embodiment, an organic acid salt of compound 1 is provided for general use in treatment of neoplasms, and in a further embodiment the salt is stabilized with carbohydrate.

Abstract: A medication container and a medication dispensing apparatus are provided for allowing medications to smoothly fall from a medication discharge opening.

Abstract: A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron beam or a beam of gamma rays. Afterwards, the packaging material is processed in such a manner that protein reactive substances or compounds formed in the packaging material during the irradiation step are at least partly removed or rendered inreactive with respect to proteins. The processing step may advantageously be performed by heating the packaging material. Preferably, the processing step involves accelerating diffusion from the packaging material of protein reactive substances or compounds. Since the protein reactive substances or compounds are removed or rendered inreactive with respect to proteins, degradation of the product which is later stored in the packaging material is considerably reduced.

Abstract: Carrying cases for medical devices and components thereof are provided. Also provided are methods for carrying medical devices and for medical testing.

Abstract: The present disclosure relates to medical packaging for the accommodation of medical supplies. The medical packaging discussed herein has a plurality of panels, including a first panel, a second panel, and a third panel, that are releasably secured together to establish a first sterile environment between the first panel and the second panel for the retention of a first medical supply, and a second sterile environment between the second panel and the third panel for the retention of a second medical supply. The panels are configured for relative movement such that movement of the first panel relative to the second panel reveals the first medical supply without compromising the second sterile environment, and movement of the second panel relative to the third panel reveals the second medical supply. The panels are arranged for sequential separation in accordance with the steps of the procedure in which the medical supplies are employed.

Abstract: A packaging system is disclosed for shipping a prosthetic tissue valve in a storage solution and preparing and loading of the bioprosthetic valve onto a catheter-based delivery system. The packaging system includes a fluid tight container filled with the storage solution attached to a delivery catheter, wherein the container surrounds the prosthetic tissue valve that is in a pre-loaded position on the delivery catheter during shipment and storage. The prosthetic tissue valve may include an attachment mechanism that attaches to the delivery catheter to properly position the tissue valve for loading within the delivery catheter. In another embodiment where the prosthetic tissue valve is not attached to the delivery catheter during shipment, the attachment mechanism may interact with the prosthetic tissue valve shipping container to prevent the bioprosthetic valve from moving during shipment.

Abstract: The present invention discloses a system for securing at least one elongate fastener to an implant. At least one adhesive capsule is inserted in a recess preferably located along a longitudinal axis of the implant. The at least one adhesive capsule may be inserted in the recess and held in place therein by a holder. A plurality of adhesive capsules and holders may be inserted in one or more recesses located substantially along the longitudinal axis of the implant. The at least one adhesive capsule preferably has a casing housing an adhesive material configured to be pierced by the at least one fastener to secure the at least one fastener to an aperture of the implant. The casing of the adhesive capsule may form an annular passageway to receive a guide wire for aiding the insertion of the capsule in an implant having a longitudinal bore along at least a portion thereof.

Abstract: Various embodiments of the present invention provide packages, inserts and pharmaceutical products that are capable of holding a plurality of medicinal units and limiting the amount of medicinal units that are dispensed from the package at one time.

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

Abstract: A vacuum packaging system for transporting a plurality of medical containers includes a plurality of medical a tray that receives and supports the medical containers. The tray includes opposing first and second side walls, opposing side and rear walls and a bottom floor. The walls extend generally perpendicularly from the bottom floor of the tray to a top edge thereof. A nesting plate is removably mountable in the tray and includes a plurality of generally cylindrical sleeves each receiving one of the plurality of medical containers. A support surface within the tray generally extends parallel to and spaced a predetermined distance from the bottom floor of the tray and receives and supports the nesting plate. An air impervious flexible film defines an internal cavity and completely surrounds the tray and the medical containers. The internal cavity is evacuated to and maintained at a predetermined vacuum level below atmospheric pressure.

Abstract: The tampon applicator assembly includes a tampon applicator section, an outer housing section, and a plunger section. The combined tampon applicator section and plunger section function as a conventional plunger-type tampon applicator. The outer housing section includes a sleeve with a proximal portion and a distal portion. The (distal) insertion end of the tampon applicator section essentially fits inside the proximal portion of the sleeve, and the distal portion of the sleeve is designed to accommodate a feminine hygiene product, such as a pad, a disposable wipe, a towelette disposal mitt, a simple disposal bag, and other products associated with menstruation.

Abstract: It has been determined that gamma sterilization of biodegradable polymer stents does not cause significant polymer cross-linking and collapse. Using sufficient spacing can lead to stents that display little if any detrimental effects from the procedure. In certain embodiments, using structures in the general region of about 100 micron spacing between the struts leads to highly functional stents that do not fuse. Further, the resulting stent has radially homogenous mechanical properties. Therefore, the stent has a uniform expansion within the lumen.

Abstract: Novel oxadiazole derivatives of the formula (I), in which R, R?, Y, X1, X2 and X3 have the meanings indicated in claim 1, are kinase inhibitors and can be used for the treatment of diseases and conditions such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and kidney diseases, in general in all types of fibroses, inflammatory processes, tumours and tumour diseases.

Abstract: The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.

Abstract: An array of disposable absorbent articles comprising a sequence of graphic designs corresponding to a wearer's stage of development. For a disposable diaper, the array of disposable absorbent article graphic designs may comprise a first absorbent article graphic design for newborns and infants, a second absorbent article graphic design for toddlers, and a third absorbent article graphic design for older wearers, and other absorbent article graphic designs.

Abstract: An assembly comprising a packaging device (20) and an intraocular lens injector (10) comprising a body (11) that contains an intraocular lens, said packaging device (20) being for receiving and storing said injector (10) prior to use, said packaging device (20) being made of a material that is waterproof, and being filled with a storage solution for maintaining at least the body (11) of said injector (10) and the intraocular lens in total immersion throughout the duration of storage, said packaging device (20) comprising a substantially rigid container (21, 22) and an opening (25) for enabling said injector (10) to be installed and removed, said container (21, 22) including at least one internal shoulder (26, 27) co-operating with a portion of the injector (10) to center and maintain its lens ejector end (14) away from the walls of said container (21, 22).

Abstract: The invention relates to an endosurgical extraction bag for collecting body tissue or body fluid, with a bag main part formed from a flexible envelope, and with a first admission opening for introducing tissue or fluid into the bag main part of the bag. Arranged in the bag main part, there is an inner envelope which is connected to the main part (bag) and opens toward the first admission opening, but adjoins the bag main part sealingly in respect of the first admission opening, and which has a second admission opening at its second end remote from the first admission opening and spaced apart from an end of the bag main part remote from the first admission opening, through which second admission opening the tissue or fluid can be introduced into the bag main part.

Abstract: The presently disclosed subject matter is directed to a multilayer coextruded film that can be used in combination with uncoated medical grade paper or uncoated Tyvek® to produce a sterile barrier system that delivers desired seal and peel characteristics with no paper tear. The combination can be particularly suitable for medical device packaging where the package is subjected to gas sterilization, such as with ethylene oxide.

Abstract: A respirator mask dispensing system is provided. It includes a carrier material and a plurality of respirator masks mounted in parallel on the carrier material by an adhesive. The carrier material is deformed between adjacent ones of the plurality of respirator masks, the deformation being configured to assist in the tearing of the carrier material at points of deformation. The carrier material with the plurality of respirator masks as mounted therein is wound on the central core member to provide a continuous roll The adhesive bonds more strongly with the respirator masks than the carrier material such that when an individual respirator mask is removed from the carrier material the adhesive will separate from the carrier material and remain attached to the individual respirator mask.

Abstract: Method for the production of a fibrinogen solution from an aqueous solution that contains functionally intact fibrinogen and is contaminated with profibrin and/or fibrin monomers and/or fibrin monomer complexes and/or fibrin split products, characterized in that the contaminations are precipitated using a non-denaturing precipitating agent at a temperature ranging from ?4° to +4° and calcium ion activity not exceeding that of a 1,000 ?M CaCl2 solution and are separated from the solution by means of filtering or centrifugation process.

Abstract: A universal surgical screw caddy. An enclosure includes a cover secured to a frame. A flexible sheet is located between an affixed to the cover and frame. A plurality of holes formed in the cover allow the surgical screws to be inserted into the caddy past a plurality of movable portions of the flexible sheet releasably holding the screws in the caddy.

Abstract: A heat-shrinkable anti-fomitic device incorporating anti-microbial metal wherein the device, in the form of a bag or tube, forms a cover for an object, preventing cross-infection by bacteria and other pathogens that may reside on the object. Anti-microbial metal ions from the cover further reduce future cross-infection from the object by killing pathogens. The anti-microbial, heat-shrinkable, anti-fomitic device can have a sterile interior that is sealed or stored flat during manufacture to maintain sterility. Therefore, no outer wrapping for the anti-fomitic device is required. The anti-fomitic device can be inverted when used to cover the object to present an outer surface that is initially sterile. A plurality of such devices can be heat shrunk to an object such that removal of the outer layer will further prevent cross contamination. Heat shrink film materials for the coverings/bags serve as a barrier to the transmission of pathogens and conform closely to the covered object.

Abstract: A needle storage and disposal cartridge is loaded with a needle receptor, and or suture and needle. By insertion of a forceps arm into the cartridge the needle receptor can be affixed to an arm of the forceps, and similarly removed after use. The forceps may conveniently be used for gripping and retaining a needle during suturing. A number of alternative suturing forceps and needle receptors are disclosed.

Abstract: The present disclosure provides a divider for packaging applications. The divider can separate products in the package into a plurality of groups, and can also contain relevant information about the products, as is required in the case of packaging tampons. The present disclosure also provides a method of packaging a plurality of products, using the divider.

Abstract: Provided are implant scaffolds comprising angle-ply arrays of two or more layers of substantially aligned fiber, methods of making and using said scaffolds, and kits comprising such scaffolds.

Abstract: A patient interface packaging that includes an integrated sizing template. The packaging system includes a container having an inner chamber containing a patient interface device having a size contained within. The packaging further includes an outer exterior having an integral flap. The integral flap includes at least one opening therethrough forming a sizing template. The size of the opening corresponds to the size of the mask contained within the package so that the opening may be fitted to the nose region of a patient's to allow the user to determine an appropriate size patient interface device that matches his or her anatomical dimensions.

Abstract: A merchandise system for disposable absorbent articles is provided. The merchandise display system includes a first line-up and second line-up of disposable absorbent articles designed to match a wearer's stage of development. The system also includes various color schemes associated with the first and second line-ups in order to facilitate consumers' identification and selection of the appropriate absorbent article configuration for a particular wearer. A pre-packaged arrangement is also provided and includes one or more disposable absorbent articles having a configuration corresponding to a wearer's stage of development; one or more disposable wipes products having a configuration tailored to the stage of development corresponding to the disposable absorbent articles; and a package, the disposable absorbent articles, the disposable wipes products and the package being arranged relative to each other for distribution together as a single unit.

Abstract: A device for treating a passage in a body part, said device having a flexible elongate body comprising a leading segment that is inserted into an opening to the passage and passed therethrough until it exits the passage and a cleaning segment that follows the leading segment through the passage and debrides the passage as it is forced therethrough.

Abstract: A container for medical products has at least one chamber. At least two lyophilized active substances and/or auxiliary substances are jointly present in the at least one chamber.

Abstract: A plastic container containing a pharmaceutical composition comprising benzoic acid or a derivative or a pharmaceutically acceptable salt thereof and a COX-inhibitor of the oxicam-type or a pharmaceutical acceptable salt thereof, wherein the container material selected from one or more members of the group consisting of a homopolymer of polypropylene (PP), a copolymer of polypropylene (PP), a homopolymer of polyethylene terephthalate (PET) and a copolymer of polyethylene terephthalate (PET), and optionally one or more non-polymeric components.

Abstract: An instrument holder for use alone or in combination with a hose/cable organizer. The holder can be made in several forms; the preferred embodiment being an elongate plastic body with fold-up wing structures carrying opposed sets of instrument receivers such as spring fingers, loops, cups and combinations thereof. The holder may be used alone or in combination with a hose/cable organizer.

Abstract: This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.

Abstract: A method and apparatus for packaging a medical device includes a package assembly that defines a multi-chambered interior. The interior chambers include a primary and a secondary chamber. A partition, which has a gas permeable vent, separates the primary chamber from the secondary chamber. The package is constructed from a variety of materials that provide the interior with a long term, low humidity, sterile environment.

Abstract: A disposable single indication orthopedic trauma surgical kit has no bone plates other than a single bone plate precountoured and sized to match an anatomic shape of a portion of a bone of a patient's extremity. The single bone plate has a plurality of fastener apertures. The surgical kit also has a plurality of fasteners with heads that are dimensioned to mate with the fastener apertures. The surgical kit also has a disposable torque driver adapted to engage the fastener heads. The foregoing components are contained in a sterile sealed container.

Abstract: A metal container and a method of preparing a metal container for a pharmaceutical formulation where the active ingredient is formoterol, a stereoisomer of formoterol, and a physiologically acceptable salt of formoterol, in a solution of a liquefied HFA propellant.

Abstract: The present invention provides new methods and kits for treating IBS; treating IBS in females; treating IBS in older subjects; and treating IBS in non-white subjects.

Abstract: The disclosure describes implantable bioprosthesis having an implantable construct with a multi-fiber array of collagen fibers attached together.