Abstract: A treatment system and method for osteopenia and osteoporosis using non-synthetic bio-available hormones, vitamins, minerals, and agents may be customized by varying the dosage and formulation of the components to maximize therapeutic effect, bioavailability, and patient comfort and compliance with their treatment method, the treatment system including a storage unit including a determined number of applications of hormones, minerals, and vitamins of appropriate dosages for treating the patient with osteopenia and osteoporosis.

Abstract: The invention relates to a method for storing and supplying a liquid, especially a liquid medical preparation. The invention further relates to a receptacle for storing and supplying a liquid, especially a liquid medical preparation. It is an object of the invention to provide a suitable receptacle and method for storing and supplying a desired liquid quantity. The object of the invention is solved by a receptacle for storing and supplying a liquid which receptacle is liquid tight and preferably gas-tight comprising a tube or a foil bag which can be compressed. The tube or foil bag preferably comprises a rigid opening portion sealingly mounted to one end of the tube. The diameter of the opening portion preferably is the same as the diameter of the tube. The rigid opening portion is stable in respect of shape. The tube diameter preferably is not more than 10 mm and, in an embodiment of the invention, the tube contains a liquid, preferably a liquid medical preparation.

Abstract: A gas-impervious container having a gas-permeable porous insert, wherein the insert contacts a flowable biomedical material, for improving access of the sterilant gas to the material.

Abstract: This invention provides novel methods for making mineralized matrices. In certain embodiments methods are provided for forming a crystalline phase within a defined liquid volume. The methods can involve combining a crystallization inhibitor; a solution that would, in the absence of the inhibitor, form the crystalline phase; and a semi-permeable barrier that excludes the inhibitor but allows the solution containing the constituents of the crystalline phase to enter, whereby a crystalline phase is formed within the liquid volume.

Abstract: Dispersible powder compositions suitable for inhalation are disclosed, the compositions including a human interleukin mutein (mhIL-4).

Abstract: The invention relates to a blood plasma container made of plastic, with a body that has a neck on one side, the body essentially having a rectangular horizontal cross section. Inside the body (1) a center link (1a) has been provided. The invention also relates to a blood plasma container made of plastic, with a body that has a neck on one side, the body essentially having a rectangular horizontal cross section. At least one holder (19) for sampling tubes (20) has been provided.

Abstract: The present disclosure provides a medical device package including a container for receiving a medical device and a self-puncturabie port.

Abstract: In order to improve a holding device for an implant, comprising a first connecting device for releasably connecting the holding device and the implant, such that very small implants, in particular, are easy to handle, it is suggested that the holding device have a second connecting device for releasably connecting the holding device and a storage unit.

Abstract: A transport device for receiving and securely holding an ossicular prosthesis for implantation in a middle ear to replace or bridge at least parts of a component of a human ossicular chain to an operating surgeon, has a substantially flat base plate of thin metal sheet having a thickness of substantially half a millimeter, a holding device integrated in the substantially flat base plate for holding the ossicular prosthesis, an outer packaging enclosing the base plate on all sides during transport, and the base plate has a device for ensuring safe transport provided with burr-shaped segments extending laterally outward from the base plate and clampable or braceable against inner walls of the outer packaging.

Abstract: A protective storage capsule is disclosed for a nasal cannula. The protective storage capsule may be used in conjunction with a nasal cannula assembly. The protective storage capsule includes a housing adapted to receive the nasal cannula and a cap to cover and protect the nasal cannula from dirt and debris when not being worn by a patient. The protective storage capsule slides along one or more of the support tubes of the nasal cannula assembly. The surfaces of the protective storage capsule may be treated with an antimicrobial film or be infused with antimicrobial nanoparticles.

Abstract: A holder (100) for storing prescribed medication doses in a sealed cup (112) is provided with a sealing strip (117) a first portion (110) of which covers the mouth of the cup and a second portion (120) carries a picture of the face of the patient for whom the medication has been prescribed. The holder (100) is provided with a rim (113) extending outwardly from the mouth of the cup and with an extension flange (114) having a flat upper surface (111) which is coplanar with the upper surface of the rim (113). The sealing strip adheres to the coplanar surfaces of the rim (113) and the flange (114) and is provided with lines of severance (130 and 131) extending from a pull-tab (151) and along opposite sides of the cup. These lines of severance (130 and 131) are arranged within the confines of the path of the seal between the sealing strip (117) and the rim (113) so that air cannot leak through the lines of severance and into the cup when storing medication doses within the holder.

Abstract: An osteoinductive bone graft substitute composition that does not return to its original shape upon hydration or manipulation is disclosed, comprising, in combination, about 86-89% by weight of a calcium phosphate particulate mineral component and about 11-14% by weight of a purified fibrillar collagen, the mineral component including about 20% to about 60% by weight of hydroxyapatite and about 60% to about 20% by weight of tricalcium phosphate. A package configured to store a bone graft composition is disclosed, comprising an inner sterile polymeric V-shaped pouch located in an outer sterile polymeric V-shaped pouch. Methods for repairing a bone defect in a patient are disclosed using the osteoinductive bone graft substitute composition.

Abstract: A catheter assembly is disclosed comprising a catheter and a receptacle enclosing said catheter. The receptacle has a first part and a second part, which parts are foldable over each other. Further, at least one sticky adhesive area is arranged on the surface of one of the parts of the receptacle in such a way that the sticky adhesive area is covered by the other part when the receptacle is in a folded disposition, and exposed to the environment when the receptacle is in an unfolded disposition.

Abstract: A catheter product package and method of forming same in which the package comprises a sheet material wrapped about the catheter product to form a package for the catheter product. The catheter product extends generally longitudinally within the package, and the sheet material extends from a point beyond the proximal end to a point beyond the distal end of the catheter product. The sheet material of the package is wrapped about the catheter product in a manner defining confronting proximal end edges, confronting distal end edges, and confronting side edges. The confronting proximal end edges, distal end edges and side edges of the sheet material are joined by a seal after the sheet material is wrapped about the catheter product to define a sealed cavity. The sheet material has a tear strip affixed to it which causes the sheet material to tear along the tear strip to thereby cause the package to open along an intended opening line.

Abstract: A film container comprises a bottom film (2) and a top film (3) connected thereto for forming at least one accommodating chamber (4) for a filling (5), in particular a pharmaceutical active substance formulation. A detachably fastened sliding element (7) which covers the accommodating chamber (4) is assigned to the accommodating chamber (4) as a safeguard.

Abstract: A storage unit is disclosed for at least one animal identification and/or animal tissue collecting device, capable of storing said at least one identification and/or collecting device. In several embodiments, such a set includes at least one container containing a specific agent designed to be applied at least partially to at least one element of said identification and/or collecting device.

Abstract: An oral pharmaceutical composition in unit dose form, each unit dose comprising a lipophilic drug substance within a unitary carrier body, said body comprising a soft, chewable, gelled oil-in-water emulsion.

Abstract: Disclosed are methods of treatment including administration of a pharmaceutical composition including brimonidine to an eye as a mist, the composition devoid of a penetration enhancer.

Abstract: Provided is a multi component topical system including at least one component including at least one first active agent coated by metal oxide; and at least one skin treating component free of the active agent. Further provided are methods of using the multi component topical system and kits including them.

Abstract: A method and an arrangement for sterilizing, in particular for sterilizing an adsorber, which has an adsorber housing that is to be filled with an adsorbent, are such that, instead of the adsorbent-filled adsorber housing being sterilized, the adsorbent is sterilized in a separate container, which is dimensioned such that the adsorbent spreads out in a thin layer in the container. Together with the adsorber housing, the container for sterilizing the adsorbent forms a closed system, such that the adsorbent can be transferred into the adsorber housing without the need for an aseptic environment. The container for receiving the adsorbent is preferably a bag, in which the adsorbent spreads out in a thin layer when the bag is lying flat on a plane surface. Since the adsorbent in the bag spreads out in a thin layer, the sterilization requires only a relatively small dose of radiation, which cannot damage the adsorbent. The bag is irradiated with high-energy radiation, in particular ionizing radiation.

Abstract: The invention provides an assembly comprising a cover and a device arranged fully or partly in the cover. The device comprises a first portion, and a second portion moveable relative to the first portion between an initial and an actuated position, and the cover comprises a cavity portion and a closure portion which together form an enclosure in which the device is arranged initially. Movement of the closure portion from an initial position in a first direction results in the second portion of the device being moved in a second direction between the initial and the actuated position, the first direction being different from the second direction. By this arrangement it is possible to provide a cover-device assembly which is easy and intuitive to use and open and at the same time ensures that the enclosed device is actuated correctly.

Abstract: A tip assembly for a liquefaction surgical handpiece having a break-away or frangible tip protector. The tip protector protects the delicate tip from damage during handling and shipment, but is easily removed prior to use.

Abstract: The present invention provides a combination drape and carrying bag unit including a singular sheet or plurality of joined sheet of pliable materials, both permeable and impermeable, of size to define a mat to accommodate a working medical procedural area thereon, upon which may be placed in single or combination, medical equipment and patient. The sheet has a drawstring casing extending about its periphery. The casing has openings therein on opposite sides of the mat and a drawstring is received in the drawstring casing and is of size to extend continuously about the periphery of the sheet when it defines a mat. The drawstring is slidably received in the drawstring casing so that when portions of the drawstring are pulled out of the drawstring casing through the openings, the periphery of the sheet forms gathers adjacent the casing to permit the periphery to reduce in size whereby the unit forms a carrying bag.

Abstract: The present disclosure relates to medical packaging for the accommodation of medical supplies. The medical packaging discussed herein has a plurality of panels, including a first panel, a second panel, and a third panel, that are releasably secured together to establish a first sterile environment between the first panel and the second panel for the retention of a first medical supply, and a second sterile environment between the second panel and the third panel for the retention of a second medical supply. The panels are configured for relative movement such that movement of the first panel relative to the second panel reveals the first medical supply without compromising the second sterile environment, and movement of the second panel relative to the third panel reveals the second medical supply. The panels are arranged for sequential separation in accordance with the steps of the procedure in which the medical supplies are employed.

Abstract: The invention relates to compositions, and methods of use thereof, containing polyphenols such as flavanols, procyanidins, their derivatives and epimers thereof, for improving vascular circulation in peripheral and/or small blood vessels.

Abstract: A transdermal patch container (10) that includes a container body (16), a first compartment (24), and a second compartment (28) is disclosed. One or more first transdermal patches (34) may be stored in the first compartment (24). One or more second transdermal patches (36) may be stored in the second compartment (28). The first transdermal patches (34) differ from the second transdermal patches (36) in at least one respect. A number of features may be incorporated to reduce the potential of being able to withdraw second transdermal patches (36) out of the second compartment (28). For instance, second transdermal patches (36) may be required to be directed through a slot (44) to enter a second compartment (28i). A flap (66) may be positioned below such a slot (58) within a second storage compartment (28ii). A plurality of vertically spaced or staggered flaps (96) may be positioned within a second storage compartment (28iv).

Abstract: A dispensing device package including a protective enclosure containing a dispensing device, e.g. an inhaler. The protective enclosure includes at least one rigid enclosure member, which in some implementations defines a recess to house a section of the dispensing device.

Abstract: A multi-part kit for administering at least one active pharmaceutical ingredient including at least one piece of chewing gum including the active pharmaceutical ingredient, the piece of chewing gum comprising gum base; and at least one further flavor-containing formulation; wherein the gum base content of the at least one further flavor-containing formulation is less than 70% by weight of the gum base content of said piece of chewing gum.

Abstract: The main object of the present invention is to provide a patch package structure including a patch containing a physiologically active ingredient and a package housing the patch, which is capable of stably retaining the physiologically active ingredient in the patch during preservation. This object can be achieved by employing the following constitution. To be specific, the present invention is a patch package structure including a patch 1 having an adhesive layer containing an organic liquid component, and a packaging member 51 housing the patch, wherein the packaging member 51 includes a first package 11, the first package 11 including an acrylonitrile resin layer 12, a moisture-absorbing layer 13 formed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 formed on the moisture-absorbing layer 13, and the acrylonitrile resin layer 12 is provided on the proximal side of the patch 1.

Abstract: A crosslinking reaction and a reaction for reducing molecular weight that take place in a hyaluronic acid-methotrexate conjugate upon irradiation with light are suppressed to improve the photostability of the conjugate. Specifically, a substance having a quenching effect and/or a radical scaveng effect is added to a pharmaceutical composition containing the hyaluronic acid-methotrexate conjugate.

Abstract: A transaction management system is capable of simply and accurately gathering information about the use of medical products with minimized human errors and automatically executing issuance of invoices of suppliers and restocking of used products on the basis of the results of use of products deposited at medical centers. The system comprises a computer system having an antenna electrically connected to a reader and a medical product encapsulated in a sterilized environment in a package. The package is provided with an IC tag arranged such that signal transmission and/or reception is disabled while the package remains unopened so that the medical product is in the sterilized condition. The IC tag becomes wirelessly communicable with the antenna when the package is opened to remove the medical product.

Abstract: A medical tubing bag disclosed herein includes a housing having an open interior area and generally opposed first and second ends defining respective first and second openings. A first guide is adjacent the first opening for guiding tubing in and out of the first opening. In an embodiment, the first opening has a center axis being offset from a center axis of the first guide. In an embodiment, a second guide is inwardly adjacent the second opening for guiding tubing in and out of the open interior area. In an embodiment, a medical system includes a medical tubing bag, a medical device, and medical tubing. The tubing has a first end coupled to the medical device, the tubing extends into the medical bag, and the tubing continues from the medical bag to a user.

Abstract: The present invention relates to substituted amido phenoxybenzamide compounds of general formula (I): in which A, R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined in the claims, to pharmaceutical compositions and combinations containing said compounds, to methods of preparing said compounds, and to the use of said compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.

Abstract: Devices and methods for locking a suture to an anchor are disclosed. In certain embodiments, a suture anchor includes a first body configured to be driven into a bone, and a second body also configured to engage the bone and coupled to the first body. At a selected embedded depth of the anchor, the second body moves towards the trailing end of the first body to facilitate a suture-lock configuration as the anchor is driven in deeper. A suture retainer such as a ring, and a flared portion at or near the trailing end of the first body, facilitate locking of a suture between the ring and either or both of the second body and the flared portion as the second body pushes on the ring that in turn pushes against the flared end. In certain embodiments, such suture-lock can be achieved substantially simultaneously as the suture anchor is driven into its final embedded depth.

Abstract: The invention concerns a kit comprising a medical device having an insertion needle and a packing providing a sterile protection for the medical device, such a medical device can be used for an infusion device providing continued medication with e.g. insulin to a patient. More precisely the invention relates to an assembly comprising a medical device comprising a mounting pad having an adhesive surface and an inserter which inserter comprises an insertion needle and a packing providing a sterile protection for the medical device which packing partly comprises a rigid material (1, 2, 7, 8, 5) and partly a soft material (10), wherein the rigid material is constructed of two angularly positioned and rigidly joined surfaces, a first and a second surface (1, 2), which surfaces (1, 2) cover two sides of the medical device (3, 4) which sides face two different directions and the non-adhesive surface of the mounting pad is not covered by a rigid surface.

Abstract: The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation.

Abstract: A container (100) for storing transdermal patches is disclosed. The container (100) includes a child-resistant mechanism (112) to reduce the likelihood of access to the transdermal patches (TP) by children. The child-resistant mechanism (112) may include first and second access components (116, 120) that may be disposed in a non-opposing manner and that may be in any appropriate form (e.g., buttons). Activation or engagement of the first and second access components (116, 120) in a particular manner allows the container (100) to assume an open configuration to access and/or load patches. In one arrangement, the first and second access components (116, 120) may be simultaneously engaged (e.g., depressed) to open the container (100). In another arrangement, the first and second access components (116, 120) may be engaged in series in a particular sequence to open the container (100).

Abstract: A medicine cover for covering a medicine container and a method for using the same is provided. The medicine cover may have a cylindrical sleeve, or a flat medicine cover, for placing over the medicine container and concealing the identity of the medicine container. The medicine cover may have a bottom having an attachment device for securing the bottom to the cylindrical sleeve.

Abstract: Containers and methods for disposing unused pharmaceutical product are disclosed. Each container (100, 200, 300) may include a container body (104, 204, 304) with an internal chamber (116, 216, 316) for storing pharmaceutical product, along with a cover (124, 224, 324) for selectively limiting access to the chamber (116, 216, 316). An encapsulation component (128, 228, 328) may be selectively disposable within the chamber (116, 216, 316), and may be operable to encapsulate the pharmaceutical product within the container (100, 200, 300). For instance, the encapsulation component (128, 228, 328) may melt and/or flow into contact with the pharmaceutical product and thereafter solidify to encapsulate the pharmaceutical product. The encapsulation component (128, 228, 328) may melt and thereafter solidify between the cover (124, 224, 324) and shell (104, 204, 304) to limit removal of the cover (124, 224, 324) from the shell (104, 204, 304).

Abstract: A carrying case (1) for a pharmaceutical injection device (21) administering a pharmaceutical to a living body includes a case unit (2, 20) and an electric charging device (3a). The case unit (2, 20) accommodates the pharmaceutical injection device (21). The electric charging device (3a) is mounted in the case unit (2, 20), includes an electric charging terminal (9) electrically connectable to the pharmaceutical injection device (21), and electrically charges the pharmaceutical injection device (21). The carrying case (1) can prevent troubles including such a situation that a user cannot charge the pharmaceutical injection device (21) while being out with the carrying case.

Abstract: The present invention relates to substituted sulphonamido phenoxybenzamide compounds of general formula (I): in which A, R1, R2, R3, R4, R5, R6, R7, R8 and n are as defined in the claims, to pharmaceutical compositions and combinations containing said compounds, to methods of preparing said compounds, and to the use of said compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.

Abstract: The device of the invention comprises a protective cover for an optical device such as a gonioscope, capsulatomy lens, wide-angle lens, or any other lens having an eye-contacting surface. The cover is made sterile and disposable for allowing multiple use of the protected optical device. The cover is made from a soft material biologically acceptable for contact with a human eye. According to one aspect, the gonioscope protective cover is used merely for physically protecting the eye-contacting surface from direct contact with the eye. According to another aspect, the gonioscope protective cover combines the protective function with an optical function that changes the direction of light so that it becomes possible to observe the light emitted from the pupil at angles that are close to the angle of full internal reflection from the pupil medium.

Abstract: A vapor hydrated packaged catheter assembly includes a gas impermeable package housing a catheter within a catheter-receiving cavity. The catheter assembly has a hydrophilic coating on at least a portion of the outer surface of a catheter tube which may be surrounded by a sleeve. The catheter assembly is disposed within the catheter receiving cavity of the package with a vapor donating liquid provided as a source of vapor to activate the hydrophilic coating. The amount of vapor donating liquid is less than the amount that would otherwise be sufficient to cause a spill hazard. The catheter assembly is ready to use due to exposure of the hydrophilic coating to a vapor produced by the vapor donating liquid.

Abstract: Packaged systems for implanting a marker in a patient and methods for manufacturing and using such systems. In one embodiment, a packaged system comprises an introducer having a cannula and a stylet configured to be received in the cannula, a marker in the cannula, and a package having a sterile compartment. The marker can have a casing configured to be implanted in a patient and a resonating circuit in the casing. The resonating circuit can comprise a coil configured to wirelessly transmit a target signal in response to a wirelessly transmitted excitation signal. The introducer is contained within the sterile compartment. In another embodiment, the marker is not loaded in the introducer within the compartment of the package.

Abstract: In one exemplary embodiment, the present invention provides a container system having an outer shell defining a cavity that is configured to receive a first medical device component therein. A support tray is sized for receipt within the outer shell of the container system and is supported above the first medical device component. In one exemplary embodiment, the support tray defines a second cavity that may receive a second medical device component. In addition, a retention tray may be positioned within the cavity of the support tray and supported above the second medical device component. The retention tray facilitates the retention of the support tray within the outer shell and also facilitates the retention of the first and second medical device components in their desired positions within the container system. Additionally, positioned to extend across an opening in the outer shell is a cover.

Abstract: The present invention is directed generally to protecting cells, tissues and organs against the damaging effects of ionizing or other damaging agents associated with radiation or chemotherapy, or degenerative diseases or processes of various organs that elicit the production of free radicals or oxidants such as peroxides, superoxide anions, hydroxyl radicals or nitric oxides, or heavy metal cations. More particularly, the present invention is concerned with methoxypolyethylene glycol thioester chelate methyl esters that are useful as protectors against tissue damage by penetrating the cell membrane to donate electrons to free radical oxidants and remove heavy metals that may react with peroxides to produce the reactive hydroxyl radical, or remove Ca++ that may be released from organelles. These chelate esters will also have utility in reducing intraocular pressure in glaucoma patients.

Abstract: A portable carrying case is described to hold medicine vials during travel, doctors' visits, etc. The case includes an open-topped box with a hinged lid and attachment means to secure the lid to the box. The case further includes a vial support platform, which may be the upper surface of the box, or a separate platform attachable to the box bottom wall. The platform has a plurality of spaced, parallel divider walls having lower edges attached to the support surface and upper edges. The divider walls have aligned left holes and aligned right holes. An elastic cord is slidable through aligned holes to cord ends outside an end divider wall. A cord lock is used to adjust the length of the cord. The support surface, walls and cord form a plurality of adjustable vial receiving compartments, with the force on each vial being equal regardless of differences in vial sizes.

Abstract: The invention provides various antibodies that bind to lymphotoxin-?, methods for making such antibodies, compositions and articles incorporating such antibodies, and their uses in treating, for example, an autoimmune disorder. The antibodies include murine, chimeric, and humanized antibodies.

Abstract: This invention describes the composition of mixtures that are a cryorganic, cryo-massage cream or liquid, for different types of skin, and a method of storing and applying this, non-viscous and thick viscous mixtures, which method can also be used for medications and food products.

Abstract: A simplified paracetamol solution for an injectable and ready-to-use preparation is only composed of paracetamol, bi-distilled water and a buffer agent, the formulation having a maximal paracetamol concentration of 1 g/100 ml, a pH between 5.5 and 6.5 and an oxygen content inferior to 0.2 ppm. A method for preparing and packaging such a solution and a device for packaging such a solution are also disclosed.