Abstract: The present invention relates to a device and method for purifying sperm cells and sperm cell DNA from biological samples containing sperm cells and other cell types. More particularly the present invention is directed to the use of sperm-specific antibodies to purify sperm cells prior to the isolation of the sperm DNA.

Abstract: The objective of the present invention is to provide both a device and a method therewith for efficient production of magnetized water useful in living body's metabolism by changing the arrangement of molecules of water, taking advantage of the phenomenon that molecules of water are disposed to form clusters and become enriched in a pulsating magnetic field.

Abstract: A method and apparatus for magnetically separating target particles of a selected type from a sample in order to produce a concentration of the target particles in the sample, or a depletion of the sample with respect to the target particles, by producing a sample mixture of the sample with magnetic particles having a selective affinity to magnetically stain the target particles; producing a flow of a buffer liquid through a tube which includes an inlet connectable to a source of buffer liquid, and an outlet for the buffer liquid; after a flow of the buffer liquid has been produced through the tube, introducing the sample mixture into the buffer liquid flowing through the tube such that the buffer liquid forms a continuous liquid carrier for the sample mixture as both are fed through the tube; and applying a magnetic field across the tube at a magnetizing station therein to cause the magnetically-stained target particles to be separated and retained in the buffer liquid within the tube at the magnetizing stat

Abstract: A device and method are disclosed, with which fluids can be treated, in particular, with which their properties can be improved. The device and method use a Klein-type field coil, through which the water to be treated is fed. According to the invention, at least one Klein-type double-coil is arranged around a through-flow pipe (3), through which the water to be treated is passed.

Abstract: Water to be treated is passed through a membrane (net), magnetic floc positioned in a portion below a level of the water to be treated is deposited to a surface of the membrane, and the surface of the membrane with the magnetic floc deposited is moved to an atmospheric portion above the level of the water to be treated. In the atmospheric portion, excess water from the magnetic floc flows downward due to gravity to concentrate the magnetic floc. A permanent magnet is located near a position to which the membrane surface with the magnetic floc deposited thereon moves. There are further provided between the magnet and the membrane surface a moving body (shell) formed by a non-magnetic material, a spatula for scraping the magnetic floc from the moving body, and a sludge vessel in which a released magnetic floc is recovered.

Abstract: A novel modified matrix system, mimicking a metastatic environment, that can be used to capture and detect viable cancer and normal cells from tissue fluid samples derived from cancer subjects and which provides effective cell separation for diagnostic and therapeutic applications in treating patients with metastatic diseases.

Abstract: A micro column system is provided for high gradient magnetic field separation of macromolecules and/or cells. The system provides fast kinetics and high efficiency as well as the purity and simplicity of a column separation. A yoke provides a magnetic field to a plurality of micro columns. A separation and release process for purifying biological material on the column includes release of the biological material from magnetic particles and elution from the column while the magnetic particles are still magnetically retained by the matrix inside the column.

Abstract: Under a magnetic field gradient, solid plastic particles floating and/or sinking in a suspending liquid (most suitably a paramagnetic one) are levitated or anti-levitated at different locations depending on their densities and diamagnetic susceptibilities.

Abstract: A method is provided for modifying cells retained in a high gradient magnetic cell separation column (HGMS). Selected cells within a heterogeneous mixture are labeled with a label comprising a magnetic particle and specific for the selected cells. The labeled, selected cells are applied to the magnetic cell separation column, which retains the selected cells. The selected cells are then modified while retained in the column and then removed to the original suspension or to a purified, homogenous suspension.

Abstract: Magnetic field generation device 5a and 5b, for applying a magnetic field to water, are located in the vicinity of an inlet 7 or an outlet 8 in a water passage area wherein pairs of electrodes 11 and 12 are arranged with intervening gaps. In the water passage area wherein the electrodes 11 and 12 are disposed, passage walls 10, which are arranged at predetermined intervals and which are perpendicular to the axial direction of a pipe line 2, define water passages, and, with the internal surface of the pipe line 2, openings 10a and 10b. The electrodes 11 and 12 are mounted on the faces of the passage walls 10.

Abstract: A magnetic sensing element detects the presence of magnetic particles in a binding assay. The magnetic sensing element has at least one planar layer of electrically conductive ferromagnetic material that has an initial state in which the material has a circular magnetic moment within the plane of the layer. The magnetic sensing element has molecules of a first specific binding member attached to it. The device also includes a fluid test medium to which the magnetic sensing element is exposed during the course of a binding assay. The fluid test medium includes magnetizable particles that become immobilized during the assay in relation to the amount of analyte in the test medium.

Abstract: For manipulation of particles in a fluidic microsystem (15) in which the particles are moved in a predetermined reference direction in a suspension liquid, the microsystem (15) is closed off at least at its end (17a, 17b) pointing to the reference direction. The particles move under the influence of centrifugal forces and/or gravitational forces in the suspension liquid which is stationary in relation to the microsystem (15), with the centrifugal forces and/or gravitational forces essentially extending parallel to the reference direction. Furthermore, the particles in the microsystem (15) are exposed to deflection forces whose direction differs from that of the reference direction. (FIG. 1).

Abstract: In a fluid filter, magnetic filtration of ferrous particles is provided by an adhesive having magnetic properties which is placed within a filter assembly in either a structural or nonstructural capacity.

Abstract: A magnetic filter removes magnetic particles from fluid communicated through the filter. The filter includes elongated, circumferentially spaced magnetic elements which capture magnetic particles entrained in the fluid. The magnetic elements must be cleaned periodically to remove the particles from the elements by moving a scraper plate from one end of the housing to the other. At the end of travel of the scraper plate, the particles are scraped upon non-magnetic end portions (which may contain residual magnetism) of the magnetic elements, from which they are flushed by fluid communicated through the inlet port out through other ports provided on the housing.

Abstract: An oil pan containing a magnetic filter apparatus includes an oil pan member having a magnet assembly reception channel. A magnetic filter assembly is received in the magnet assembly reception channel, and attachment means are provided for attaching the magnetic filter assembly to the oil pan member. The magnetic filter assembly separates ferro-magnetic particles from oil in the oil pan member and traps the separated particles on the magnetic filter assembly. The magnetic filter assembly includes a magnet support unit which is attachable to the attachment means. A magnet unit is supported by the magnet support unit. The magnet unit provides a high magnetic flux region to circulating oil in the vicinity of an oil pump intake tube for trapping metal particles on the magnetic filter assembly. The magnet unit includes a plurality of individual magnets arrayed in highly cohesive relationship.

Abstract: A device for treating fluid with ultra-high magnetic force including the casing of the device as subdivided with partition panels into Nos. 1, 2, 3 chambers, and a separation chamber, as well as fluid passages. Both a louver and a plurality of latticed bodies providing magnetic fields are juxtaposed into the No. 1 and 3 chambers, respectively, to magnetically treat the fluid. The No. 2 chamber is provided to free the floc from the fluid, and a separation chamber is provided to precipitate the floc and discharge it outside. Slats of the louver are designed to taper off downstream. The louver and latticed bodies are removable from either the No. 1 or No. 3 chambers, respectively, and one side of the casing is detachable from the body of the casing. Permanent magnets are secured to each of the outer surfaces of both sides of the casing, providing magnetic fields through the Nos. 1, 3 chambers and a separation chamber.

Abstract: This invention relates to a method to make biopolymers such as proteins or nucleic acids migrate by applying a spatially distributed magnetic field to a solution containing biopolymers marked with magnetic beads. In this case, marking the biopolymers to be fractionated with magnetic beads of different sizes or materials causes different migration speeds and thus causes different positions of the biopolymers after migration. Molecules to be fractionated can be separated in such a manner as mentioned above.

Abstract: A continuous, hybrid magnetic field gradient device for colloidal magnetic affinity separation having an axially-rotating horizontal glass tube, and a plurality of axially located repeating magnetic units. Each magnetic units consists of an alternating current solenoid that surrounds the chamber followed by computer-controlled electromagnets carrying a direct current. The on-off cycle of the electromagnets is used to control the residence time of target-bound magnetic particles in the chamber thereby allowing the separate collection of the particle and target rich fractions and the target-lean fractions without interrupting the feed flow. The azimuthally flowing alternating current in the solenoid introduces transient axial and radial forces as well as torque on the magnetic particles, promoting mixing.

Abstract: A method and apparatus for retrieving magnetic casing fragments from a well using a shrouded magnet are disclosed. Retrieving casing fragments allows the determination of weight loss from the casing to assist in analyzing the integrity and the condition of the casing and to determine whether more expensive analysis is required. The shrouded magnet, that is formed by a non-magnetic container enclosing a source of magnetic field, recovers metal casing fragments by attracting them and other magnetic materials from oil and gas well fluids passing by the shrouded magnet device, which fragments are easily separated from the device by removing the source of magnetic field from the container.

Abstract: The structure of a fuel pipe magnetizer comprises a pair of semicircular permanent magnets, which forms a circular magnetized body mounted in an open end of a sleeve, the other end of the sleeve has a ridge with a hole at the center portion thereof, and a slot formed axially along the side for quick installation of the fuel pipe, one semicircular permanent magnet is placed inside of the sleeve, and then the fuel pipe is inserted through the slot into the sleeve, and finally the other semicircular permanent magnet is sealed into the open end of the sleeve, whereas one sector of the fuel pipe will be sealed by the permanent magnets.

Abstract: A device for applying electrostatic and magnetic fields to a fluid includes an outer conduit 48 and an inner conduit 50 forming a fluid passageway 86 therebetween. The inner conduit is connected to a DC power source and the outer conduit along with electrode needles 84 in electrical communication therewith are connected to ground. A baffle 82 is positioned within the passageway to impart a spiral motion to the fluid flowing therein.

Abstract: The magnetic pole device of the present invention has four polar magnets and any number of interpolar magnets adjacent to and in between said polar magnets. The interpolar magnets are positioned to progressively rotate towards the orientation of the four polar magnets. Such a magnetic device would create an even flux within a liquid sample and cause the radial movement of magnetized particles toward the inner wall of the surrounding magnets.

Abstract: The invention relates to a means for separating magnetic particles from a composition. The means comprises an elongated protective cover (1) that comprises a recess (2) extending from the upper end towards the lower end thereof, the recess comprising a movable magnetic rod (4), the proportion of the length of the rod to its thickness being at least about 2:1. The invention can be used in different applications especially in the fields of biotechnology, biochemistry, and biomedicine. Collecting particles by using the means is easy and fast.

Abstract: A magnetic oil filtering apparatus is provided which fits onto an oil filter mounting stem of an engine block which includes oil output channels. The magnetic oil filtering apparatus includes an adaptor unit which fits onto the oil filter mounting stem and includes a magnetic assembly attached to the adaptor unit. Engine oil flows from the engine, through the oil output channels, through the adaptor unit, through the magnetic assembly, back through the adaptor unit, through an oil filter cartridge which is attached to the oil filter mounting stem and which is in communication with the adaptor unit, through a stem oil input channel in the oil filter mounting stem, and back into the engine. As a result, engine oil is treated with magnetic lines of force to trap metal particles in the vicinity of the magnet elements prior to entry of the engine oil into the oil filter cartridge. In addition, an oil cooler assembly can be connected to the adaptor unit.

Abstract: An improved portable water purifier of a type having a pitcher with a lower terminal wall and being divided vertically by a lateral partition into an upper compartment for holding raw water and a lower compartment for holding purified water, and a filter depending from the lateral partition into the lower compartment for purifying the raw water into the purified water. The improvement includes a base having a weight and replaceably supporting the pitcher thereon and acting as a coaster therefore, and a permanent magnet having a weight and encased throughout the base for delivering a concentrated and polarized magnetic charge through the lower terminal wall of the pitcher and into the purified water so as to polarize the purified water until its molecules are gradually rearranged from a normal agglomerated state into a more linear, organized, and substantially more permeable state that increases a body's ability to absorb and assimilate the purified water.

Abstract: An oxygen generator is designed to enrich a fuel supply or water supply and is provided in the hollow interior thereof with a positive magnetic body, a negative magnetic body, a number of far infrared granules and pebbles. The granules and the pebbles are caused by a magnetic force to collide with one another, thereby resulting in liberation of the oxygen molecules contained in the granules and the pebbles. The oxygen molecules so released are mixed with the fuel supply or water supply.

Abstract: Methods comprise processing wastewater to produce useful products. Preferably wastewater is ash leachate from landfills which is processed using magnetohydrodynamic treatment followed by electrolytic cell treatment to produce sodium hypochlorite. Methods further comprise removal of hazardous substances from wastewater for subsequent storage and processing of wastewater.

Abstract: A filter cartridge magnetic attachment includes a heat sink carrier member which includes magnet-reception channels, and carrier-embedded magnets are received in the magnet-reception channels. A top modular magnet/shunt array is located on a top side of the carrier member, and a bottom modular magnet/shunt array is located on a bottom side of the carrier member. The filter cartridge magnetic attachment is mounted on a oil filter cartridge and separates metallic particles out from the oil that circulates through the oil filter cartridge. The carrier-embedded magnets include a first directional orientation carrier-embedded magnet which includes a positive pole end and a negative pole end. The carrier-embedded magnets also include a second directional orientation carrier-embedded magnet which includes a positive pole end and a negative pole end.

Abstract: A reusable magnetic device for the extraction of ferrous particles from a body of fluid, wherein the device comprises a plurality of magnets and soft ferrous metal spacers arranged in an alternating sequence to form a stack, adjacent magnets being arranged with like poles facing, a non-magnetic and non-ferrous end piece terminally disposed at a first end of the stack, and a non-magnetic housing that contains the magnets, the spacers and the end piece. The magnetic device can be installed in a vessel to provide a fluid filtering assembly.

Abstract: The invention relates to a method for solid-phase microextraction and analysis of substances in a carrier fluid, in which a collector is brought into contact with the stirred fluid containing the substances for a sufficient time and is then subjected to a solid-phase extraction directed at at least one substance adhering to the collector, and desorbed substances are transported for analysis by means of a carrier gas, in which the carrier fluid containing the substances is stirred in a receptacle of a magnetic stirrer by means of a coated magnetic stirring element as the collector, and/or the carrier fluid is made to move intimately relative to the collector by means of ultrasound, and then the stirring element is placed in a solid-phase extraction device.

Abstract: In a preferred embodiment, an apparatus for automated magnetic separation of materials in laboratory trays, including: a frame upon an upper surface of which a multiwell laboratory tray may be placed; a base plate on which is mounted a plurality of upstanding magnets disposed below the upper surface; and apparatus to raise the base plate such as to insert the upstanding magnets into interwell spaces in the laboratory tray.

Abstract: A magnetic cleaning tool having a housing defining a cavity, a plunger partially disposed within the cavity, and a magnet located on the plunger is provided. Withdrawal of the plunger from the cavity moves the magnet along the cavity and thereby removes the magnetic field from one end of the housing. This removal of the magnetic field allows a user to easily detach any particles adhered to the exterior surface of the housing due to the presence of the magnetic field by simply pulling the plunger and moving the magnet. The assembly may also include a peripheral skirt that assures the removal of adhered particles, and straps that facilitate securement of the assembly to another body, such as a tank. A method of using the magnetic cleaning tool to remove metallic fines from lapping compounds is also provided.

Abstract: A method and apparatus for magnetic separation of particles within a container. In one embodiment, a container contains a number of particles and a number of magnetically susceptible particles. A number of magnets are arranged in a plane and is placed close to the container. The magnetic poles of the magnets are arranged in a pattern to apply magnetic fields oriented perpendicular to the plane on the container. The pole pattern provides in consistent separation across the container of the number of magnetically susceptible particles from the rest of the particles.

Abstract: An apparatus for optimizing the rheological properties of a viscous fluid is particularly designed to reduce the viscosity of the fluid so that it may be more readily transported from a subsurface reservoir to the surface. The apparatus includes housing having a first through bore defining a cross-sectional flow area and longitudinal flow path for fluid through the bore. The housing has an inlet end and an outlet end and is designed for connection in a flow path from a subsurface reservoir. A flow restriction device is adjustably mounted in the through bore to define a reduced area orifice of adjustable size for restricted flow, so as to accelerate the fluid and produce shear. A magnetic unit may also be selectively connected to the housing to produce a magnetic field across the fluid, further reducing viscosity.

Abstract: A magnetic biological particle separation device comprising a permanent magnet structure substantially surrounding a vessel containing a liquid and a biological sample in colloidal suspension in the liquid is described. The magnetic separation device comprises a window through which to view the liquid. The permanent magnet structure comprises a plurality of permanent magnets arranged in such a manner to provide for superpositioning of the external magnetic field generated by each magnet. The external magnetic field acts on magnetic beads attached to the biological sample, causing the sample to move toward the inner wall of the vessel. The permanent magnets do not completely surround the outside of the vessel to allow the liquid to be poured out of the vessel, substantially leaving the sample.

Abstract: The invention concerns a device for collection of magnetic particles. The invention further concerns a system for transfer of material from a plurality of source vessels to a plurality of target vessels, the device comprising a plurality of collecting members each of which can be manipulated independently. The invention further concerns a method for detection of biological entities being fluorescent label, wherein the entities are bound to magnetic particles. The fluorescent emission is concentrated by clustering the magnetic particles utilizing magnetic force.

Abstract: An apparatus and method for use in magnetic separation of magnetically attractable particles suspended in a liquid. The apparatus includes a magnetic separator plate having a plurality of channels, one for each column of wells of a multi-well assay plate which is received by the magnetic separator plate. A plurality of magnets are positioned in each channel so that when the magnetic separator plate receives the multi-well assay plate, the magnets attract the magnetically attractable particles to create a pellet of material of a substance of interest on a side wall within each associated well.

Abstract: A filter separator for purification of liquid hydrocarbons has a housing provided with an inlet pipe and an outlet pipe, a filtering element located in the housing, a magnetic screening including a plurality of rods, a drive provided for the magnetic screen, the drive being formed by a plurality of cup-shaped blades connected with the rods.

Abstract: A housing cannot be made compact by only securing a space corresponding to a reservoir tank at the upper part of the housing, and the space at the upper part of the housing cannot be utilized if the reservoir tank is integrally provided to the upper part of the housing. An axle driving apparatus comprising a tubular reservoir tank erected on the upper surface of the upper wall surface of the housing for accommodating an HST, wherein, since the reservoir tank is thinly elongated and is freely bendable, it can be disposed in a limited space. The housing is divided into a first room and a second room with which the reservoir tank communicates. Further, a first magnet is disposed at a position where the first and second rooms are connected, and a second magnet is disposed in the proximity of an oil filter connected to a closed circuit of the HST so that impurities can be removed.

Abstract: The present invention is directed to provide a liquid magnetic processing unit that can activate a liquid flowing in a thick pipe and can perform water treatment. The liquid magnetic processing unit wound around the pipe in which the liquid flows and that activates the liquid by magnetic force, which comprises a water treatment sections having a band wore around the pipe and magnet housings equipped to the band in an inserting manner and that house a plurality of permanent magnets inside, in which the water processing sections are covered with a case that consists of a non-magnetic material.

Abstract: A multi-mass filter for separating particles of a multi-species plasma includes a chamber, which defines an axis. A radial electric field is crossed with a magnetic field (E×B) to move the particles of different mass (M1, M2 and M3) on respective trajectories into respective first, second and third regions. Specifically, particles M1 are confined in the first region, while both particles M3 and M2 are ejected from the first region into the second region and only the particles M3 are ejected from the second region into the third region.

Abstract: Provided is a liquid handling device comprising: a cylindrical actuator cavity in a substrate, the actuator cavity intersected by two or more actuator channels; one or more chambers with an access channel adapted to connect to a separate one of actuator channels; and a actuator comprising (a) a cylindrical body having a cylinder axis and having therein a liquid-handling compartment with, arrayed along the cylinder axis, a first end and a second end, the liquid-handling compartment being closed at the second end, (b) a dispensing channel located at the second end and traversing the cylindrical body, the dispensing channel adapted to be separately aligned with the actuator channels, wherein the actuator is adapted to receive in a seal-tight manner a plunger that operates to confine an effective chamber defined by the plunger and the second end by moving toward the second end or to expand the effective chamber by moving toward the first end.

Abstract: A method for separating magnetic particles dispersed in a fluid by magnetic attraction, characterized in that an object fluid in which magnetic particles are dispersed is passed through a magnetized rotary tube, magnetic particles are made to adhere by magnetic attraction to magnetized surface in the tube, the flow of the fluid is suspended before the capacity of magnetic attraction of the tube lowers, the magnetized surface is demagnetized, an exhaust fluid for exhausting magnetic particles in the tube is made to flow under pressure through the tube, the exhaust fluid mixed with magnetic particles is discharged, and the magnetic particles are separated from the exhaust fluid.

Abstract: A holder (2) for sample liquid containers, e.g. Eppendorf vessels (15), is horizontally displaceable between a working position above a magnetic arrangement (4) and a heating position above a hotplate (5). The latter are supported on a baseplate (3) which can be vertically displaced by means of a lifting device (9) between a lowered passive position and a raised active position in which the magnetic arrangement (4) and the hotplate (5) act on the sample liquid in the Eppendorf vessels (15) and attract ferromagnetic particles suspended there. To improve the interaction between the ferromagnetic particles and the sample liquid, the magnetic arrangement (4) can be transversely moved by a stepping motor (6) between a first position, in which, for example, a magnetic plate (14) acts on a row of Eppendorf vessels (15) from the right side, and a second position, in which said magnetic plate (14) acts on the same row of Eppendorf vessels (15) from the left side.

Abstract: An ultrasonic energy source is used to provide a variable force for measuring the binding forces between molecular entities and for sensing the presence of an analyte in a test sample. The device includes a surface that has a first binding member attached thereto and one or more particles that have a second binding member attached thereto. A reaction vessel is provided for exposing the surface to the particles whereby, if the first binding member has a binding affinity for the second binding member, a complex is formed between individual first binding members and individual second binding members and the particles thereby become immobilized with respect to the surface. The ultrasonic energy source is positioned for applying a variable ultrasonic force onto the surface, and the position of the particles is monitored as the intensity of the ultrasonic force is varied.

Abstract: Separation apparatus and method for separating magnetic and/or magnetically-labeled particles from a test medium in a reaction chamber which incorporates baffles, a spinner, a stirrer, or a plunger operable to be displaced along a collection surface to define a narrow flow path through which the particle-laden test medium must flow. The collection surface is a thin-walled non-magnetic material having a plurality of magnetic pole faces positioned therearound. Test medium within a reaction chamber is caused to flow past a collecting surface, and a high-gradient magnetic field is applied to the surface to capture magnetically responsive particles in the test medium. The particles are deflected toward the collection surface in the flow path for the test medium. The narrow flow path assures that substantially all of the particles pass within the high-gradient magnetic field along the collection surface.

Abstract: A magnetic treatment device for fluid fuels, which exhibits a cylindrical flow chamber (6) with a conical part (17) widening in the direction of flow (A) and a conical, magnetic insert (16) with at least two flat and/or annular permanent magnets (10,11,12,13) arranged axially at a distance from each other, whereby the magnetic insert is held against the direction of flow with a force, e.g. intrinsic weight and/or the force from a spring and is mounted in the region of the conical part in such a manner that it can be moved axially, and in which the permanent magnets (10,11,12,13) are held at a distance from each other by spacing rings (14) or discs made from non-ferromagnetic material which are placed only in an inner region, between mutually facing surfaces of the permanent magnets, and a bearing shoulder (19) is allocated to at least one permanent magnet (10,12) in the wall of the conical part (17) of the flow-chamber (6).

Abstract: Materials and methods for making and using magnetically enhanced composite materials are provided. Surfaces coated with such composites can be used to improve fuel cells, material separators, and other applications. A variety of devices can incorporate such composites, including fuel cells, separators, batteries, and electrodes that effect electrolysis of magnetic species.

Abstract: An assembly and method for collecting and releasing magnetic materials includes an elongated permanent magnet (A) within an elongated cover (B) constructed from non-magnetic material for providing a collection area for the magnetic materials thereon opposite the magnet. Apparatus (C) separates the magnet to a more remote position in relation to the collection area for releasing magnetic materials from the elongated cover. The magnet and the cover may be moved while in superposed closely adjacent relation for collecting magnetic material and thereafter separated for releasing magnetic material collected on the cover. A driven conveyor (D) may be included Ln the assembly for transporting the magnet and the cover through a coolant liquid containing magnetic materials in the form of particulate matter formed during a machining operation.

Abstract: A method for separating inclusions from an electrically conductive liquid flow using electromagnetic forces, wherein the inclusions and the liquid have differing electrical conductivities. The flow is exposed to a spatially heterogeneous magnetic flux produced by a continuous static magnetic field.