Container With Follower Patents (Class 222/386)
  • Patent number: 12005185
    Abstract: Provided herein are dry powder formulations comprising at least one active pharmaceutical ingredient suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including respiratory conditions, hemodynamic collapse, seizures, migraines, and other conditions.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: June 11, 2024
    Inventors: Scott Lyman, Barry Bleske
  • Patent number: 11992108
    Abstract: Device for packaging, dispensing and applying a solid or pasty block of cosmetic product The present application relates to a device for packaging, dispensing and applying a block of solid or pasty cosmetic product, comprising a longitudinal tubular case having an open first end, intended for dispensing the cosmetic product, and an opposite second end that is closed by a base accommodating a mechanism for driving a support for holding said cosmetic product in translation along the case, characterized in that the device has, at the open first end of the case, an external envelope with a longitudinal central axis offset radially with respect to a longitudinal central axis of an external envelope of the device at the opposite end of the case that is closed by the base.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: May 28, 2024
    Assignee: L'Oreal
    Inventors: Stéphane Leroux, Alain Berhault
  • Patent number: 11964297
    Abstract: This invention is a gun shaped device used in the application of caulk, paste and or other semi solid high viscosity fluids. The device contains a barrel portion for the tube to be inserted into, and a plunger portion with a flat round metal piece with a fitting that attaches to a set of shortened rods. The set of shortened rods acts as a plunger and goes through a guide toward the back of the handle. The barrel can be shortened for use of smaller tubes of caulk.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: April 23, 2024
    Inventor: Richard Brewington
  • Patent number: 11958027
    Abstract: A re-mixing dispenser for containing and dispensing a liquid. The dispenser may have one or more tubes, each containing a different liquid. At least one of the liquids may be re-mixed in situ, using a special two-piece plunger and plunger rod. A mixing piece of the two-piece plunger is moveable independently of a top piece and has blades that allow it to move through the liquid. A plunger rod is removably attached to the mixing piece and is operable to move the mixing piece up and down within the tube during mixing. The two plunger pieces are joined and moved as a single plunger during dispensing.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: April 16, 2024
    Assignee: Southwest Research Institute
    Inventors: Cole Buss, Eric Kroeger, Taylor W. Batholomew
  • Patent number: 11931531
    Abstract: A delivery device for delivering an instrument into a catheter assembly may include a syringe, which may include a barrel and a plunger movable within the barrel. The plunger may include a handle and a stopper coupled to a distal end of the handle. The stopper may include a channel. The delivery device may include a guidewire disposed within the barrel and extending through the channel. In response to depression of the plunger, the guidewire may move through the channel and a first end of the guidewire may be advanced in the distal direction. A second end of the guidewire may be fixed.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: March 19, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Megan Scherich, Jonathan Karl Burkholz, Curtis H. Blanchard, Weston F. Harding, Yiping Ma
  • Patent number: 11827443
    Abstract: An aerosol foam dispenser for dispensing a foam antiperspirant or deodorant composition. The foam dispenser can have a pressurized container adapted for one or more propellants and a liquid deodorant or antiperspirant composition; a valve assembly, which can be a metered valve assembly, having a valve stem; an actuating mechanism in operative communication with the valve assembly, a dome with a skin contacting surface and one or more exit orifices in fluid communication with the valve stem; and a dip tube.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: November 28, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Matthew John Martin, Matthew Corey Cataudella, Scott James Murschel, Nathanial David Thulin, Laurie Michelle Taragano
  • Patent number: 11772060
    Abstract: Device for preparing a cosmetic composition, set of capsules and associated preparation process The invention relates to a device (10) for preparing a cosmetic composition comprising: —a structure (28) defining a housing (30) extending along a longitudinal axis (X-X?), —a piston (36) movable in translation in relation to the structure (28) along the longitudinal axis (X-X?) in the housing (30), and —an outlet nozzle (32) opening at one end of the housing (30), suitable for being fluidically connected to a receptacle. The housing (30) receives removably a plurality of capsules (16) aligned coaxially along the longitudinal axis (X-X?), at least one of the capsules (16) containing at least one constituent of the cosmetic composition (12). The piston (36) is mounted movable through the capsules (16) to successively perforate each capsule (36) and convey contents of each capsule (16) to the outlet nozzle (32).
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: October 3, 2023
    Assignee: L'OREAL
    Inventors: Eric Dehaudt, Paul Couderc
  • Patent number: 11718465
    Abstract: A piston for a reservoir of a dispenser of a fluid product without air intake, and presenting a central axis X includes both sealing means and also guiding means. The sealing means extend in a plane orthogonal to the axis X and define a single external sealing line in a closed loop, distal from the axis X, capable of coming into contact with an inner wall of the reservoir 10. The guiding means include a base from which extends one or more tabs with free ends defining external guide points, distal from the axis X, capable of coming into contact with the inner wall of the reservoir.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: August 8, 2023
    Inventors: Eric Rossignol, Emir Ezzina, Etienne Briere
  • Patent number: 11712711
    Abstract: Sealant dispensing cartridge assemblies including radially expandable collets are disclosed. A plunger head assembly includes a ram head attached to a plunger rod. As the plunger rod is advanced into the sealant cartridge, the ram head presses against a rear side of a movable plunger against an opposing force created by a sealant contained in the cartridge on a front side of the plunger. As the plunger rod is further advanced, the collet contacts the ram head and radially expands against the inner sidewall of the plunger. The resulting radial force presses the sidewall of the plunger against the inner surface of the cartridge to thereby reduce or prevent unwanted leakage of the sealant around the plunger.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: August 1, 2023
    Inventors: Paul Kuchinski, Oscar Santillan
  • Patent number: 11666706
    Abstract: A syringe barrel includes: a hollow body portion that is configured such that a gasket is slidably insertable therein. The syringe barrel is made of a resin that has a total light transmittance of 80% or more. A scale is disposed at an inner circumferential surface or an outer circumferential surface of the body portion, the scale being visible from an outside of the syringe barrel and being configured to indicate a liquid amount. The scale is formed by (i) a stepped structure having a step height in a range of 0.001 to 0.15 mm in a radial direction, and/or (ii) an embossment.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: June 6, 2023
    Inventors: Katsuyuki Takeuchi, Eiji Yagishita, Nobukazu Akaike
  • Patent number: 11654242
    Abstract: Precision low-dose, low-waste syringe configurations have a reduced diameter lumen for dispensing 0.01 ml increments of contents. Plunger and lumen configurations and a needle interface eliminate dead space. Ergonomic attachments improve the control and precision of delivery of syringes. An attachment main body includes a gripping surface to permit a user to engage the attachment and move the attachment main body, and thus the syringe plunger relative to the syringe barrel using sliding movement. Optical enhancement features are provided on the attachment to improve the readability of gradations and plunger position. The attachment may be provided with an assist feature, which may be a traction wheel mounted on the attachment body. An alternative configuration suitable for syringe contents of higher viscosity may include a pair of toothed pinion gears on a wheel and which cooperate with respective toothed racks formed on or fastened to the syringe body.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: May 23, 2023
    Assignee: Innomed Technologies, Inc
    Inventors: John H. Joseph, Minh Bui, Rod Peterson
  • Patent number: 11612276
    Abstract: A sanitizing apparatus includes a main housing, a dispensing member, a supporting platform, and a sanitizing fluid pouch. the main housing comprises a front wall, a first sidewall, a second sidewall, a rear wall, a bottom wall, and an opening. The front wall, the first sidewall, the second sidewall, the rear wall, the bottom wall of the main housing together form an internal space accessible through the opening of the main housing. The dispensing member is inserted into the internal space through the opening of the main housing. The dispensing member comprises a dispensing mechanism. The sanitizing fluid pouch is filled with a sanitizing fluid and is flexible and deformable. The supporting platform is placed within the dispensing member. The supporting platform comprises a supporting plate on which is seated the sanitizing fluid pouch. The supporting platform further comprises a pressure-applying member.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: March 28, 2023
    Inventors: Jorge Alberto Gimenez, Deborah Medel-Gimenez
  • Patent number: 11596962
    Abstract: A micro pump vessel has an outer vessel on one side of which a button is formed and an outer vessel lid which is hinge-coupled to one side of the outer vessel to be opened and closed. In the vessel, a first and a second pistons are installed on an upper surface of cosmetic contents, and thus, when the cosmetic contents are pumped and used by the operation of a micro pump, the first and the second pistons lower to exhaust all the cosmetic contents so as not to discard the remaining cosmetic contents.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: March 7, 2023
    Inventor: Seong Il Kang
  • Patent number: 11597580
    Abstract: Silicone-containing cartridges having a plunger at one end thereof are effectively sealed against moisture penetration by introducing a silicone oil composition having a viscosity of from 5000 mPa·s to 100,000 mPa·s between the walls of the plunger and the interior surface of the cartridge wall.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: March 7, 2023
    Assignee: WACKER CHEMIE AG
    Inventors: Uwe Scheim, Peter Schoeley
  • Patent number: 11541416
    Abstract: A reusable cartridge piston for use with film bag cartridges comprises a piston base, an intermediate portion and a piston head. An extension axis extends from the piston base through the intermediate portion and through the piston head. The piston also includes a lip sections extending radially outwardly with respect to the extension axis from a sidewall of the piston head, the piston base and the piston head being spaced apart from one another by the intermediate portion, with a gap between the piston base and the lip sections. The lip sections are respectively spaced apart from one another by slits formed between two neighboring lip sections, with the slits extending in a radial direction with respect to the extension axis of the piston. The piston base, the intermediate portion, the piston head and the lip sections are formed as one piece.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: January 3, 2023
    Inventor: Richard Lavelanet
  • Patent number: 11542090
    Abstract: A system for mixing two cosmetic products includes a tubular bottle defining a first reservoir containing a first product to be mixed, a tubular cartridge defining a second reservoir containing a second product to be mixed, a retaining device suitable for retaining the cartridge on the bottle in an injection position in which the first reservoir communicates with the second reservoir via the inlet orifice of the base and the injection orifice of the cartridge, a perforator having an upper edge designed to perforate the cap that seals the inlet orifice when the cartridge occupies the injection position, and a piston that seals the lower end of the cartridge and that is axially slidably mounted between an initial bottom position and a final top position in order to push the second product through the injection orifice from the second reservoir to the first reservoir.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: January 3, 2023
    Assignee: COSMOGEN SAS
    Inventor: Lucie Pidoux
  • Patent number: 11490941
    Abstract: One aspect relates to a device for providing a bone cement from two starting components, having a hollow cylinder-shaped first container, in which a monomer liquid as first starting component can be stored, a hollow cylinder-shaped second container comprising a container wall, a first internal space, and a second internal space, whereby a bone cement powder as second starting component can be stored in the first internal space, and whereby the monomer liquid can be conveyed into the second internal space, a fluid-conducting conveying means arranged between the first internal space and the second internal space, whereby the first container and the second container are axially connected to each other.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: November 8, 2022
    Assignee: Heraeus Medical GmbH
    Inventors: Sebastian Vogt, Thomas Kluge
  • Patent number: 11400471
    Abstract: An airless container includes a cylindrical container body storing a contained material, which is a fluid, in an airtight state, and a pump attached to an upper edge portion of the container body and configured to externally discharge the contained material. The airless container further includes a bottom lid that closes a lower opening portion of a container bottom portion of the container body, and a piston in the container body between the pump and the bottom lid, which is slidable in the container body in an airtight state. The piston includes a flexible piece that is deformable in a portion that comes into contact with the bottom lid. The flexible piece is deformable against the sliding of the piston toward the bottom lid.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: August 2, 2022
    Inventors: Katsunori Shimakura, Masayoshi Takaoka, Tatsuro Nagao
  • Patent number: 11400228
    Abstract: The present invention relates to a medicament delivery device (10) comprising a housing (12, 14); a medicament container holder (90), arranged movable in relation to said housing (12, 14) and capable of accommodating a medicament container (92); an biased activator (160) comprising a plunger rod (164), which plunger rod (164) is arranged to act on the medicament container (92) for delivering a dose of medicament through a medicament delivery member (102 when said biased activator (160) is operated; a manually operable dose setting member (72) operably connected to both said housing and said medicament container holder such that manual operation of said dose setting member (72) will cause the medicament container holder (90) with the medicament container (92) to move towards said plunger rod (164) for setting a dose of medicament to be delivered; a dose drum (56) releasably connected to the dose setting member (72) through a releasable connection mechanism (68, 84I) such that when the dose setting member is op
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: August 2, 2022
    Assignee: SHL MEDICAL AG
    Inventor: Kasper Enge
  • Patent number: 11337503
    Abstract: Disclosed is a foundation container having a discharge pump therein, in which a contents container of stretchable material for storing cosmetic contents is coupled inside a container main body, and is fixed by a middle cap, and the contents container is provided with a rounded curved portion (42) at a lower edge thereof, an annular bent portion (43) at a lower center portion thereof, and spaced protrusions (44) protruding radially on an upper bottom surface, such that the contents container is evenly pressed from the rounded curved portion during the pumping operation of the pump, and even when the contents container is compressed, the gap is secured to discharge minimal contents, whereby the contents are smoothly discharged, and by the branch structure of the distribution plate and the discharge plate, it is possible to minimize the residual contents and improve use efficiency while discharging the cosmetic contents evenly.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: May 24, 2022
    Inventor: Jin Woo Kim
  • Patent number: 11279548
    Abstract: A container for dispensing personal hygiene products comprising a tube with a piston section fit into one and a head assembly and closing the opposite end. The head assembly has a concave top with an aperture through which the contents of the tube are dispensed when the piston is pressed by the user. A Is provided with an opposing convex surface to create a volume between the head assembly and the cap assembly wherein a small amount of dispensed material may be stored.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: March 22, 2022
    Inventor: Edgar Hugo
  • Patent number: 11167091
    Abstract: A precision syringe includes a syringe barrel and plunger that has a base, an internal portion, and an external portion. The internal portion of the plunger extends longitudinally into the syringe barrel. The internal portion has a first end coupled to the base and a second end that is configured to push fluid out of and/or suction fluid into the syringe barrel. The external portion extends longitudinally along an outer surface of the syringe barrel. The external portion has a first end coupled to the base and a second end that is configured to receive an applied force that causes the plunger to move relative to the syringe barrel so that the second end of the internal portion is actuated through a portion of the syringe barrel (e.g., to dispense fluid from or suction fluid into the syringe barrel).
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: November 9, 2021
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Donny Suh, Ronald Linke, Tyler Scherr
  • Patent number: 11027910
    Abstract: The invention relates to a piston for an optionally pressurized container, the piston having a sidewall, an upper side and a bottom side, and at least a first circumferential seal, wherein at least the upper side of the piston is closed by a closure and made of a first elastic material, wherein the upper side is configured to deform upon a pressure change acting on the upper side, wherein the sidewall is made of a second material which is different from the first elastic material, wherein the first circumferential seal is positioned on the sidewall on its outer surface. The invention further relates to an optionally pressurized container comprising a piston as mentioned above, to a process of discharging a product from said container and to a process of manufacturing said container.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: June 8, 2021
    Assignee: The Procter and Gamble Company
    Inventors: Stefano Bartolucci, Andrew William Franckhauser, William Mercer Benson, Nathan Daniel Grubbs
  • Patent number: 10987470
    Abstract: A single-hand controlled syringe with plunger extension includes a barrel, a plunger fit to the barrel, and a plunger extension integrated with the plunger. The plunger extension consists of a head, a back, and a body between the head and the back. The body of the plunger extension is oriented parallel to the plunger, with integrated connection at the back of the plunger extension and the back of the plunger. Depressing the head of the plunger extension moves the syringe from the contracted state to the retracted state. Such syringe with plunger extension is useful to draw blood or fluid with a single hand.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: April 27, 2021
    Inventor: William A. Aqeel
  • Patent number: 10794804
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: October 6, 2020
    Assignees: BioPath Automation, LLC, Sakura Finetek U.S.A., Inc.
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Patent number: 10792068
    Abstract: A method of manufacturing an optical obturator includes providing an injection mold including a mold cavity defining an outer surface of the optical obturator and a core pin centrally positioned within the mold cavity. The core pin defines an inner surface of the optical obturator. In particular, the core pin may be cantilevered to the injection mold. The method further includes injecting a first material between the core pin and the mold cavity to form the tubular shaft and injecting a second material between a distal portion of the core pin and a distal portion of the mold cavity to form the optical tip.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: October 6, 2020
    Assignee: Covidien LP
    Inventors: Gregory Fischvogt, Danny Berry, Emily Davis, Norvin Asido
  • Patent number: 10759590
    Abstract: In one aspect, the invention is directed to a portable paste dispenser having a container for storing paste, the container having a cylindrical part and a conical part, a nozzle at the end of the conical part, a piston, disposed inside the cylindrical part of the container, and a shaft connected to the piston, the shaft having a limited foldability so that when the shaft is pushed towards the piston, it still is able to move the piston along the cylindrical part, where the piston includes foldable bellows walls, thereby upon applying force on the piston, the piston straightens up, resulting in a conical form correspondingly to the conical part, thereby allowing fully emptying the container.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: September 1, 2020
    Inventor: Hillel Harris
  • Patent number: 10556737
    Abstract: A dispensing device having an elongated dispenser body which is elliptical in cross-section through its midsection, has an open top end, and has a dispensing bottom end; a cylindrical ratchet support member which is removably disposed within the open top end of the dispenser body, wherein the ratchet support member comprises a through hole one and or more ribs disposed on the inside of its circumferential sidewall; and a wheel-shaped ratchet which is removably disposed within the ratchet support member, wherein the ratchet has radially extending teeth which are configured to engage with the ratchet support member ribs, the ratchet configuration allows rotary motion in a first direction over the ribs, the ratchet configuration prevents rotary motion in a second, opposite direction past a point defined by the ribs, and the ratchet comprises ribs disposed on the top surface of the ratchet wheel.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: February 11, 2020
    Inventors: James Eric Johanson, Chad E. Lagace
  • Patent number: 10532476
    Abstract: A retaining element for a razor cartridge has a top portion that includes an aperture therethrough, a bottom portion, and a side portion connecting the top portion to the bottom portion to define a volume between the top portion and the bottom portion, a container having a top opening, a lubricating composition in the container and a first spherical lid to cap the container. The top opening is sized to hold the first spherical lid so that the first spherical lid freely rotates without translation. The container is positioned in the volume so that the first spherical lid at least partially protrudes from the aperture. The lubricating element emits onto an outer surface of the first spherical lid when the first spherical lid rotates.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: January 14, 2020
    Assignee: BIC VIOLEX S.A.
    Inventors: Amalia Skarmoutsou, Nikos Chatzigrigoriou, Christos Pandis, Nikos Skounakis, Aliki Douka
  • Patent number: 10478852
    Abstract: A device for dispensing a material has a container for holding the material, a piston movably arranged within the container and a spindle in cooperation with the piston. The device is configured such that the spindle and the container are rotatable relative to each other to move the piston for dispensing the material. The piston and the spindle are adapted to anti-twist lock against each other in a first axial position of the piston relative to spindle. And in a second axial position of the piston relative to spindle the anti-twist lock between the piston and the spindle is suspended. The device helps minimizing any residual dental material upon attempting to empty the device.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: November 19, 2019
    Inventors: Helmut Pauser, Marc Peuker
  • Patent number: 10435226
    Abstract: A dosing dispenser includes a housing, a traveler, and a plunger. The dosing dispenser also includes a driver. The housing defines a chamber, and the traveler and plunger are each positionable within the chamber. The traveler is configured to selectively position the plunger along an axis in at least one direction within the chamber.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: October 8, 2019
    Assignee: DOSELOGIX, LLC
    Inventors: Timothy Gayle Phipps, Saundra D. Naughton, Craig Jay Cochran, John Britton S. Mockridge, Daniel Lee DeYoung, Dale Melton Coker
  • Patent number: 10406293
    Abstract: An assembly for a drug delivery device is provided, the assembly comprising at least one feedback feature. The feedback feature is configured to indicate the end of a dispense operation to a user by giving an audible and/or tactile feedback.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: September 10, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Paul Richard Draper, Paul Griffin
  • Patent number: 10399763
    Abstract: A gel foundation container including a pump, the gel foundation container further including content discharge grooves radially formed on a distribution plate; second control protrusions, which are formed inside the content discharge grooves, for controlling the flow of content; a discharge plate formed at the upper end of the distribution plate; and content discharge holes radially formed at the discharge plate at the same position as the content discharge grooves of the distribution plate, wherein the content discharge holes are formed so as to gradually become larger outwardly from the center of the discharge plate, and thus gel foundation is equally discharged in the same amount onto the entire discharge plate when being pumped.
    Type: Grant
    Filed: September 7, 2015
    Date of Patent: September 3, 2019
    Inventor: Sungil Kang
  • Patent number: 10391249
    Abstract: A dropper syringe apparatus includes a cylindrical barrel, a plunger assembly, and a needle. The cylindrical barrel storing the fluid includes a flanged first opening and a second opening. The plunger assembly, inserted into the cylindrical barrel, includes a plunger shaft and a flexible hollow bulb. The plunger shaft includes a flanged upper end, a lower end, and a central lumen. The plunger shaft moves in an upward and a downward direction within the cylindrical barrel. The central lumen extends from the lower to the flanged upper end of the plunger shaft for accommodating the fluid. The flexible hollow bulb is fixedly attached to the flanged upper end and in fluid communication with the central lumen. An external force exerted on the flexible hollow bulb exerts a pressure on the fluid accommodated within the lumen. The needle draws or dispenses the fluid from or to the external body.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: August 27, 2019
    Inventor: Belal Hassanzadeh
  • Patent number: 10391259
    Abstract: A syringe includes a barrel with an internal surface defining an internal bore therein, a plunger disposed within the internal bore of the barrel, and a dose divider disposed on the plunger. The dose divider includes a first end, a first abutment surface, and a second abutment surface. The first abutment surface is spaced apart from the first end in the axial direction by a first axial distance, and the second abutment surface is spaced apart from the first end in the axial direction by a second axial distance. The second abutment surface is spaced apart from the longitudinal axis of the plunger by a first radial distance, and the first radial distance is greater than a radial dimension from a longitudinal axis of the barrel to the internal surface of the barrel near a proximal end of the barrel.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: August 27, 2019
    Inventors: Huy Tran, Perry Croll
  • Patent number: 10300481
    Abstract: A centrifuge tube assembly includes an elongate tubular receptacle having upper and lower ends and a side wall that extends between the ends. A cap attached to the receptacle carries a common inlet/outlet port formed therethrough for communication with an interior chamber of the tubular receptacle. A liquid impermeable piston is longitudinally movable through the receptacle chamber and sealably interengages an interior wall of the receptacle. The piston separates upper and lower regions of the chamber, which respectively communicate with the inlet/outlet port and a pressure neutralizing vent. Biological products are introduced into and aspirated from the receptacle through the inlet/outlet port.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: May 28, 2019
    Inventor: Patrick Pennie
  • Patent number: 10279116
    Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: May 7, 2019
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Aubrey Plumptre, Christopher John Jones, Roberts Frederick Veasey
  • Patent number: 10188585
    Abstract: A device for self-administration of liquid medication supplied by combining a tablet of medication located within the device with a dissolving liquid from a source which dissolves the tablet upon contact. The formed medication solution is then available for delivery to the sublingual area of a patient.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: January 29, 2019
    Inventor: Yuri Busiashvili
  • Patent number: 10155089
    Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing, a cartridge holder for receiving a cartridge, a lead screw and means for driving the lead screw during dose dispensing. The lead screw is coupled to the cartridge holder such that the cartridge holder is axially displaced with respect to the housing and the lead screw during dose dispensing.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: December 18, 2018
    Assignee: Sanofi
    Inventors: Tom Oakley, Karl Hewson, Stuart Milne, Mark Pawulski
  • Patent number: 10105731
    Abstract: A cartridge is provided having at least one reception chamber (2), which extends in the longitudinal direction, for a medium to be dispensed, having an end face (4) and a cartridge wall (3) which bound the reception chamber (2) and which are injection molded in one piece, with the end face (4) having an outlet for the medium, and with the cartridge wall (3) having a first film (6) at its inner side bounding the reception chamber (2) which extends over the total cartridge wall (3) and is non-releasably connected to the cartridge wall (3). A method of manufacturing such a cartridge as well as a multicomponent cartridge are furthermore provided by the invention.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: October 23, 2018
    Assignee: SULZER MIXPAC AG
    Inventor: Josef Ettlin
  • Patent number: 10040602
    Abstract: A container is provided having a pleated sidewall construction enabling expansion and contraction of an internal volume. A bottom of the container is provided with stabilizers to assist with maintaining the container in an up-right position when expanding and contracting the container. The container is especially useful for concentrated liquids which require the addition of a secondary liquid such as water.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: August 7, 2018
    Inventor: Walter R. Talgo
  • Patent number: 9737127
    Abstract: A device to contain and deliver fluid substances includes: a container including a housing suitable for containing a substance to be delivered; a feed element for feeding the substance outside the container, including a piston portion inserted inside the housing of the container, and a conveyance portion connected to the piston portion; a dispenser cap connected to the conveyance portion and such as to push the piston portion into the housing of the container and to deliver the substance; at least one element to guide the movement of the piston portion into the housing of the container; wherein the piston portion of the feed element is operated only manually by acting onto the dispensing cap.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: August 22, 2017
    Assignee: LUMSON S.P.A.
    Inventor: Matteo Moretti
  • Patent number: 9731078
    Abstract: A syringe for injecting solid, hard and rough granular material includes: a longitudinal injection chamber having constant section and an internal diameter of less than 4.5 mm, having a distal outlet mouth for the flow out of the material, whose surface is the same as the injection chamber, and a proximal mouth, in which granular material is inserted; a plunger sealedly mobile along the injection chamber, joined to a stem which enters the injection chamber through the proximal mouth, the plunger having: a transversal section which sealingly couples with the surface of the injection chamber, and having an operative surface, facing towards the distal mouth of the injection chamber; and a body projecting longitudinally internally of the injection chamber, fixed substantially axially to the operating surface of the plunger, having a diameter that is less than 70% of that of the injection chamber and a length greater than 6 mm.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: August 15, 2017
    Assignee: C.G.M. S.P.A.
    Inventor: Corrado Saverio Parmigiani
  • Patent number: 9469061
    Abstract: A piston has a one-piece body having a first portion and a second portion. The second portion is integrally formed with the first portion, is flexibly movable between a first position and a second position relative to the first portion, and is biased toward the first position. The first portion has an orifice, and the second portion has a seal member. When the second portion is disposed in the first position, the seal member is disposed in a sealed arrangement with the orifice, and when the second portion is disposed in the second position, the seal member is disposed in an unsealed arrangement with the orifice.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: October 18, 2016
    Inventor: Charles M. Frey
  • Patent number: 9376239
    Abstract: Provided is a pull-top style discharge member for a package to be mounted on a dispenser. The package discharge member is provided with an outer frame 70 having an opening in the center thereof, a cap 71 that closes the opening in the outer frame 70, and can open the opening by being pulled, and a sheet 61 disposed on the reverse surface of the outer frame 70 and the cap 71 and formed with a discharge hole 61a in the form of slits to allow passage of food contents. The sheet 61 and the outer frame 70 are welded together, and metallocene polyethylene is used as the material of the outer frame 70, while polypropylene is used as the material of the sheet 61.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: June 28, 2016
    Inventors: Toshimitsu Edamatsu, Suzuko Yamato, Kenta Imao
  • Patent number: 9173880
    Abstract: The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-6 receptor (hIL-6R). The formulations may contain, in addition to an anti-hIL-6R antibody, at least one amino acid, at least one sugar, and/or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
    Type: Grant
    Filed: January 7, 2011
    Date of Patent: November 3, 2015
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Daniel B. Dix, Kenneth S. Graham, Douglas Kamen, Scott M. Walsh
  • Patent number: 9144821
    Abstract: A piston includes a piston body which is surrounded by a media side, by an oppositely disposed drive side and, at the peripheral side, by a piston jacket, wherein the piston jacket forms a connection between the media side and the drive side. The piston jacket is arranged about a piston axis, wherein the piston jacket is connected to the piston body via a web element so that a peripheral groove is formed on the media side between the piston body and the piston jacket. A cover element is arranged at the media side, and has a drive side surface which lies directly on the media side surface of the piston body.
    Type: Grant
    Filed: December 8, 2010
    Date of Patent: September 29, 2015
    Assignee: SULZER MIXPAC AG
    Inventor: Manfred Obrist
  • Patent number: 9089647
    Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: July 28, 2015
    Assignee: Roche Diagnostics International AG
    Inventors: Roger Haenggi, Urs Rindlisbacher, Franco Moia, Marcel Mueller, Christoph Huwiler, Florian Kuhni, Joerg Wermelinger, Andreas Lischewski, Christian Classen, Tilo Callenbach, Louis Widmer, Maurice Ducret
  • Patent number: 9073526
    Abstract: A brake fluid pressure control device for a vehicle includes: a base body; reservoirs to store brake fluid in the base body; and a single lid member secured to the base body. The reservoir has a reservoir hole, a piston that slides inside the reservoir hole, and a spring that biases the piston. The lid member hermetically seals the reservoir holes. The lid member includes a plate member with which the springs make contact and a ring-shaped sealing member held between one face of the base body to which the plate member is secured and the other face of the plate member opposed to the one face to provide a sealing function. In the lid member, a screw hole is disposed outside a region surrounded by the sealing member and a communication passage communicating with the reservoir holes is provided inside the region.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: July 7, 2015
    Assignee: NISSIN KOGYO CO., LTD.
    Inventors: Takuro Kodama, Motoyasu Nakamura
  • Publication number: 20150136812
    Abstract: A dispenser has a container whereof one end is sealed by a sealing piston which, in relation to the container, is adjustable in a first direction. There is arranged, on the side of the sealing piston remote from a product chamber of the container, a spreading spring which is in engagement with the inner wall of the container and prevents movement of the sealing piston in a second direction which is opposed to the first direction. The spreading spring is made from synthetic material and has a central part from which a plurality of fingers arranged distributed over the periphery extend radially outwards. Each finger is connected to the central part in a manner articulated at its radially inner end and is in engagement at its radially outer end with the inner wall of the container. The central part and the fingers are constructed in one piece with one another and each finger is connected to the central part by way of a web, wherein in the region of the web a cutout is formed.
    Type: Application
    Filed: May 23, 2012
    Publication date: May 21, 2015
    Inventor: Rainer Krallmann