Sample Holder Structure Patents (Class 324/321)
  • Patent number: 9389287
    Abstract: In a nuclear magnetic resonance (NMR) spectrometer, a sample spins about an axis tilted at a magic angle, a corrective magnetic field generating portion produces a corrective magnetic field, and a control portion controls the operation of the corrective magnetic field generating portion. An arithmetic unit included in the control portion uses at least one of BZ(1), B1(1)e, and B1(1)o or the linear sum of at least two of them as the first-order magnetic field component of the corrective magnetic field, uses at least one of B2(2)e, B2(2)o, B2(1)e, and B2(1)o or the linear sum of at least two of them as the second-order magnetic field component of the corrective magnetic field, and uses at least one of BZ(3), B3(1)e, B3(1)o, B3(2)e, B3(2)o, B3(3)e, and B3(3)o or the linear sum of at least two of them as the third-order magnetic field component of the corrective magnetic field.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: July 12, 2016
    Assignee: JEOL Ltd.
    Inventor: Yusuke Nishiyama
  • Patent number: 9372246
    Abstract: The flow-through NMR analyzer comprises: a solution feeding pipe for flowing a sample; a superconducting magnet that encloses a housing space, which is surrounded by a side wall of the solution feeding pipe, around an axis of the solution feeding pipe such that a static magnetic field is generated along the axis of the solution feeding pipe; a vacuum container which houses the superconducting magnet in a cooled state and which encloses the housing space around the axis of the solution feeding pipe; and an RF coil which applies high-frequency electromagnetic waves to the sample inside the housing space and which detects an NMR signal from the sample. The RF coil is integrally formed with the side wall of the solution feeding pipe in a region of the solution feeding pipe that is enclosed by the superconducting magnet and the magnetic field correcting coil.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: June 21, 2016
    Assignee: Kobe Steel, Ltd.
    Inventor: Takashi Miki
  • Patent number: 9366736
    Abstract: A magic-angle-spinning (MAS) nuclear magnetic resonance (NMR) probe is described that includes double containment enclosures configured to seal and contain hazardous samples for analysis. The probe is of a modular design that ensures containment of hazardous samples during sample analysis while preserving spin speeds for superior NMR performance and convenience of operation.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: June 14, 2016
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Herman M. Cho, Nancy M. Washton, Karl T. Mueller, Jesse A. Sears, Jr., Mark R. Townsend, R. James Ewing
  • Patent number: 9279869
    Abstract: An NMR probe has a sample tube insertion port for introducing and withdrawing the sample tube into and from the probe, a sample tube support providing support of the sample tube during NMR measurements, a tubular sample tube passage connecting together the sample tube insertion port and the sample tube support and capable of transporting the sample tube between them, and a gas stream generator for producing a gas stream in the sample tube passage to move the sample tube between the sample tube insertion port and the tube support. The gas stream generator is mounted at an intermediate (non-end) position in the sample tube passage.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: March 8, 2016
    Assignee: JEOL Resonance Inc.
    Inventors: Hideyuki Shinagawa, Tadashi Shimizu, Shinobu Ohki, Takahiro Nemoto, Eijiro Baba, Katsuya Hioka
  • Patent number: 9190707
    Abstract: The invention relates to a method for manufacturing an RF filter comprising several resonator cavities and an RF filter manufactured by the method. The resonator cavities are formed into shape from a copper plate in a first manufacturing phase. In a second manufacturing phase the formed resonator cavities are inserted or integrated into a chassis material of the RF filter.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: November 17, 2015
    Assignee: Prism Microwave, Inc.
    Inventors: Mika Hedemaki, John Kevin Pryor, William Baldwin Johnson
  • Patent number: 9110132
    Abstract: Imaging signals from one or more surface coils are directed outwardly through a rear end portion of an imaging bore of an imaging machine, such as a magnetic resonance imaging machine (MRI). Initial processing of the imaging signals can be carried out within the imaging bore and transmitted through a pair of releasable connectors to external imaging processing equipment. By routing the surface coil imaging signals through the open rear end of an imaging bore, wires and other signal processing components need not be squeezed through the relatively limited space available around the front portion of an imaging bore. Fluid passages can be provided through the pair of releasable connectors for the passage of heating fluids, cooling fluids, and pressurized gasses including anesthesia gasses.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: August 18, 2015
    Inventor: Chris Chiodo
  • Patent number: 9063196
    Abstract: A slow Magic-Angle Spinning NMR device and method are detailed that provide high resolution and high sensitivity metabolic profiling of biological samples. A new 1H-PASS sequence suppresses line broadening in the various biological samples. The device and method allow metabolic changes in small animals to be tracked through continuous investigations of minimally-invasive blood and tissue biopsy samples over a sustained period and allow intact biological objects with sizes up to a few centimeters to be studied.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: June 23, 2015
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Jian Zhi Hu, Ju Feng, Hardeep S. Mehta
  • Patent number: 9063060
    Abstract: A high-resolution solid-state NMR spectrometer which can measure a disklike sample. The spectrometer includes: a stator having an air bearing disposed within the static magnetic field, the rotor being disposed in the stator; and an engaging mechanism mounted in a one-end portion of the rotor and detachably holding a sample holder that holds the disklike sample.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: June 23, 2015
    Assignees: JEOL Resonance Inc., Kyoto University
    Inventors: Munehiro Inukai, Yasuto Noda, Kazuyuki Takeda, Kiyonori Takegoshi, Takashi Mizuno
  • Publication number: 20150130463
    Abstract: The invention features a portable device for monitoring changes in the rheological state of multiple samples by NMR based measurement. The rheological changes can be, for example, gelation occurring during limulus amoebocyte lysate (LAL) testing for endotoxins or blood coagulation. The inventive method entails organization of individual NMR tubes in a disposable cartridge where the tubes are connected through a top cover, provided with movable actuators to push the reagent in the reagent compartments of the individual chambers to the reaction chambers in a predetermined sequence.
    Type: Application
    Filed: June 25, 2013
    Publication date: May 14, 2015
    Applicant: T2 BIOSYSTEMS, INC.
    Inventors: Parris S. Wellman, Matthew Blanco, William Peine
  • Patent number: 9018954
    Abstract: A sample holder structure is provided with which it is possible to reduce current noise derived from electromagnetic induction, etc. in electricity-detection electron spin resonance spectroscopy. Also provided is a process for producing the structure. The material of the sample holder, which is used in an electricity-detection electron spin resonance device, is an FR-4 resin, alumina, glass, or Teflon. The sample holder has four wiring leads formed on the surface thereof. The four wiring leads each has a three-layer structure composed of a nickel layer, a gold layer, and a resist layer which have been arranged in the order from the sample holder surface, and the sample holder has the shape of the letter T. The sample holder has, formed in the end thereof, a gold pad for affixing a sample, and the gold pad has a multilayer structure composed of a nickel layer and a gold layer arranged in this order from the sample holder surface.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: April 28, 2015
    Assignee: Hitachi, Ltd.
    Inventors: Yoshiki Yonamoto, Naotoshi Akamatsu
  • Publication number: 20150102812
    Abstract: A monitoring cell, used to perform a measurement in an NMR spectrometer of a reaction fluid produced by a reaction vessel, has a body having inlet and outlet transport coaxial capillaries for transporting the reaction fluid between the body and the reaction vessel. Cooling lines are also positioned coaxially with the transport capillaries to transport cooling liquid between the body and the reaction vessel. The cell further has a hollow sample probe for insertion into the NMR spectrometer and a coupler section that removably connects the sample probe to the body so that the inlet transport capillary extends through the body into the interior of the sample probe and the outlet transport capillary is sealed to the sample probe to allow reaction fluid that enters the sample probe via the inlet transport capillary to exit the sample probe via the outlet transport capillary.
    Type: Application
    Filed: March 31, 2014
    Publication date: April 16, 2015
    Applicant: Bruker Biospin Corporation
    Inventors: Brian Marquez, Michael Fey, Kimberly L. Colson, Robert Krull, Eckhard Bez, Don Piroli, Werner E. Maas
  • Publication number: 20150088449
    Abstract: A system (20) for quality assurance of a magnetic resonance (MR) imaging device (23) used in magnetic resonance based radiation therapy planning includes a phantom (10) weighing less than 18.2 kg (40 lbs.). The phantom includes a three dimensional spatial distribution of MR and CT imagable elements (12) located in an MR and CT inert foam support (14), and an MR and CT inert external support structure (16) which surrounds and hermetically seals the foam support. The spatial distribution is sized to completely fill an imaging volume of the magnetic resonance imaging device.
    Type: Application
    Filed: March 22, 2013
    Publication date: March 26, 2015
    Inventors: David Leslie Foxall, Melanie Suzanne Kotys, Ajit Devaraj
  • Patent number: 8975894
    Abstract: A magnetic resonance imaging (MRI) apparatus includes a housing which has a bore to which a magnetic field for use in an MRI scan is applied, a moving table on which an inspection target may be placed and that enters the bore of the housing, a projector which projects an image onto an inner wall that forms the bore of the housing, and a controller which controls the projection unit and transmits a video signal to the projector.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: March 10, 2015
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Myung-kyu Lee
  • Publication number: 20150061678
    Abstract: An NMR spectrometer (1?) has a sample changer (4?) with at least one cylindrical sample holder (7?, 7?) for receiving an elongated NMR sample at a loading position (5) and for transferring the NMR sample into the measurement volume at a transfer position (6). The sample holder is open in an upward direction and the cylinder axis of the cylindrical sample holder is inclined at the loading position by an angle of inclination a of between 30 and 60 degrees with respect to the vertical and it extends vertically at the transfer position. A positioning device is provided, which transfers the NMR sample at or after the transfer position into the measuring position in the measurement volume with a vertically aligned sample axis of the NMR sample. The spectrometer enables a more ergonomically favorable feed of the sample.
    Type: Application
    Filed: August 13, 2014
    Publication date: March 5, 2015
    Inventors: Thomas Bocher, Diether Maier, Volker Reiss
  • Publication number: 20150061679
    Abstract: A patient support apparatus configured to support a patient is provided. The patient support apparatus includes a table having a support surface to support the patient. The table includes a patient support assistance unit with at least one handle element.
    Type: Application
    Filed: September 3, 2014
    Publication date: March 5, 2015
    Inventors: Yvonne Candidus, Daniel Driemel, Hubertus Fischer, Wolfgang Kraus, Thomas Kundner, Martin Zigann, Stephan Zink
  • Publication number: 20150061670
    Abstract: An apparatus and method for NMR analysis of a plurality of core samples includes a core holder (11) that holds a core sample under pressurized conditions. A radio frequency coil (51) disposed about the core holder (11) generates a pulsed-mode magnetic field component over a sample volume occupied by the core sample. A support structure is removably secured to the respective core holder. A permanent magnet (65A, 65B) has an open configuration such that it is removably disposed into a position within the support structure about the radio frequency coil and the core holder. The open configuration allows the same permanent magnet to be used for NMR analysis of a plurality of core samples without the need for depressurizing the respective core holder and disassembling the core holder and corresponding load frame for each core sample. It also allows multiple core samples to be prepared for NMR analysis while separated from the NMR measurement apparatus.
    Type: Application
    Filed: May 15, 2012
    Publication date: March 5, 2015
    Applicant: Schlumberger Technology Corporation
    Inventors: Edmund J. Fordham, Jonathan Mitchell
  • Publication number: 20150048830
    Abstract: An MRI apparatus and a bed board assembly with illumination are described. The MRI apparatus includes: a frame with a cavity; a support rail disposed in the cavity; a bed board, which enters or exits the cavity moveably via the support rail; and an illumination unit disposed in a front portion of the bed board, for emitting light to provide illumination when the MRI apparatus is performing a scan. Space inside the cavity may be saved, and an examination subject may have the impression of being in a more open and brighter space, alleviating the subject's discomfort or fear effectively.
    Type: Application
    Filed: July 28, 2014
    Publication date: February 19, 2015
    Inventors: Jian Hua Pei, Wen Qiang You
  • Publication number: 20150048825
    Abstract: A magnetic resonance imaging (MRI) apparatus includes a housing which has a bore to which a magnetic field for use in an MRI scan is applied, a moving table on which an inspection target may be placed and that enters the bore of the housing, a projector which projects an image onto an inner wall that forms the bore of the housing, and a controller which controls the projection unit and transmits a video signal to the projector.
    Type: Application
    Filed: October 30, 2014
    Publication date: February 19, 2015
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Myung-kyu LEE
  • Publication number: 20150048829
    Abstract: Method for operating a thermal insulation device (100) comprising a screen (101, 102, 103, 104) for insulating a first member (21) and/or a second member (20; 30; 16; 10; 30) from a thermal radiation, the method comprising: a heat-exchange step in which heat is exchanged between a stream of a fluid, notably a gas, and the screen, notably a step of transferring heat from the heat screen to the stream, and a use step in which the stream is used for guiding the first member (21) and/or for driving the movement of the first member and/or for exchanging heat with the first member, notably for cooling the first member.
    Type: Application
    Filed: February 7, 2013
    Publication date: February 19, 2015
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Gaël De Paëpe, Eric Bouleau
  • Patent number: 8958865
    Abstract: A lesion phantom is disclosed, which is a spherical ball having a cavity formed therein for housing contrast agents or medicines, and is enabled for the quantitative evaluation of a medical image in drug development and evaluation. In an embodiment, the cavity of the lesion phantom is coupled to a tapering ring and is configured to be sealed by a silicon plug, in order to ensure that contrast agents or medicines can be fed into the cavity easily and conveniently without causing any problem, such as overflowing, a bubble residue problem, radioactive contamination, etc. Moreover, by the arrangement of a retractable fixing bar, the positioning of the lesion phantom can be adjusted flexibly at will, and additionally by the tapering of the tapering ring, the lesion phantom can be prevented from being damaged by any extreme, sudden, unjust, or improper force exerted, and thus the lifespan of the lesion phantom can be prolonged.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: February 17, 2015
    Assignee: Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
    Inventors: Shiang-Lin Hsu, Yu-Ching Ni, Meei-Ling Jan
  • Publication number: 20150022205
    Abstract: A magnetic resonance imaging system includes a control unit configured to (a) compare a plurality of magnitudes of a field of a coil of a local coil, wherein each magnitude of the plurality of magnitudes is measured at a different time; and (b) determine, based on on a comparison result, whether to stop or advance a position adjustment apparatus of the patient couch of the magnetic resonance imaging system.
    Type: Application
    Filed: July 15, 2014
    Publication date: January 22, 2015
    Inventors: Dominik Paul, Raphael Schwarz
  • Publication number: 20150015261
    Abstract: The embodiments relate to a magnetic resonance imaging device, where the cladding of the patient bore of the MR imaging device includes a conductive layer.
    Type: Application
    Filed: June 17, 2014
    Publication date: January 15, 2015
    Inventors: Ralph Kimmlingen, Norbert Rietsch
  • Publication number: 20150008922
    Abstract: The invention relates to a Nuclear Magnetic Resonance (NMR) spectroscopy device adapted for carrying out 1D and nD homo- and heteronuclear NMR spectroscopy measurements of a plurality of nuclei, comprising an RF coil adapted to transmit RF to and/or receive RF from a measuring volume, wherein the RF coil forms part of a non-tuned radiofrequency circuit. The invention further relates to a method of NMR data acquisition, a method of manufacturing a NMR spectroscopy device and a NMR-device holder.
    Type: Application
    Filed: December 21, 2012
    Publication date: January 8, 2015
    Applicant: Wageningen Universiteit
    Inventors: Aldo Hendrikus Velders, Raluca Maria Fratila, Maria Victoria Gomez Almagro, Stanislav Sykora
  • Publication number: 20150002153
    Abstract: The present invention is related to systems and methods for chemical and biological analysis and, in particular, to systems, apparatus, and methods of sample conditioning and analysis.
    Type: Application
    Filed: October 4, 2012
    Publication date: January 1, 2015
    Inventors: Edmund Y. Ting, Alexander Lazarev
  • Patent number: 8912796
    Abstract: A sample container (2) for NMR measurements defines a volume (V) of sample substance. The sample container (2) has a first interface (G1) towards an environment (1) and a second interface (G2) towards the sample substance (3). A susceptibility jump at the second interface G2 is sufficiently large that the maximum value of |B?G2/B0| within the volume (V) is at least 0.5 ppm. The geometry of the sample container (2) is selected in such a fashion that, when a homogeneous magnetic field B0 has been applied, a location-dependent relative field change F is present in the volume (V), which is larger than 20 ppb at least at one point in a center partial volume (V1) and a first residual field (R1) in the center partial volume (V1) is smaller than 1.6 ppb. A second residual field (R2a) in the lower partial volume (V2a) is smaller than 30 ppb.
    Type: Grant
    Filed: March 11, 2012
    Date of Patent: December 16, 2014
    Assignee: Bruker BioSpin AG
    Inventors: Dirk Wilhelm, Thomas Speck, Oskar Schett
  • Publication number: 20140361770
    Abstract: A magnetic resonance imaging (MRI) system, method and/or computer readable medium is configured to effect improved parallel MR imaging with reduced unfolding artifacts by using either or both of: (a) an unfolded “intermediate” diagnostic image to create a more accurate mask for use in further processing raw image data for final unfolded diagnostic images; and/or (b) an extension of coil sensitivity maps by replication (rather than curve-fitted extrapolation) for use in final unfolding of diagnostic images.
    Type: Application
    Filed: June 10, 2013
    Publication date: December 11, 2014
    Inventor: WAYNE R. DANNELS
  • Patent number: 8896312
    Abstract: An NMR measuring system with an NMR probehead has at least one cooling device (5a, b) generating a vibration spectrum of individual selective frequencies. The cooling device is mechanically connected to a vibration absorber (9a, 9b) having an oscillating mass element (27), whose resonance frequency is adjusted to the vibration frequency of the cooling device and/or to one of its harmonics. The cooling device has a cooling head which is thermally connected to an NMR resonator of the probehead via a flexible mechanical element. A vacuum housing of the probehead is designed in two parts which are mechanically connected via at least one damping element (30a-d). The lower part and the upper part of the vacuum housing are additionally mechanically flexibly connected to each other in a vacuum-tight fashion via a corrugated bellows (8a, 8b). The system minimizes sidebands in NMR spectra.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: November 25, 2014
    Assignee: Bruker BioSpin AG
    Inventors: Philippe Stauffenegger, Klemens Kessler, Marco Tomaselli, Sven Radke, Bernhard Felber
  • Patent number: 8896311
    Abstract: A measuring instrument and a measurement method which measures, using magnetic resonance, images such as a functional image, a morphologic image of an object to be measured eliminate the influences of the moving speed of the object to be measured during moving, thereby obtaining a precise measured image.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: November 25, 2014
    Assignee: Kyushu University, National University Corporation
    Inventors: Hideo Utsumi, Kazuhiro Ichikawa, Tetsuhiko Takahashi
  • Patent number: 8896309
    Abstract: In order to increase the speed at which a user of a magnetic resonance imaging (MRI) system may electrically or optically connect and physically attach a spine coil unit to the MRI system, the spine coil unit includes a connector extending away from a side of a spine coil housing. The spine coil unit is positioned on a patient table of the MRI system and moved along the patient table of the MRI system adjacent to or in physical contact with a corresponding MRI system-side connector. A lever rotatably attached to the spine coil housing may be rotated into a corresponding recess in the MRI system to physically attach and electrically or optically connect the connector of the spine coil housing and/or to positionally fix the spine coil housing relative to the MRI system-side connector.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: November 25, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventor: Heinz Hahn
  • Patent number: 8896308
    Abstract: Gradient coil assemblies for horizontal magnetic resonance imaging systems (MRIs) and methods of their manufacture. Some embodiments may be used with open MRIs and can be used with an instrument placed in the gap of the MRI. In general, concentrations of conductors or radially oriented conductors may be moved away from the gap of the MRI so as to reduce eddy currents that may be induced in any instrument placed within the gap. Systems for directly cooling primary gradient and shield coils may be utilized and various coil supporting structures may be used to assist in coil alignment or to facilitate use of an instrument in the MRI gap.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: November 25, 2014
    Assignee: ViewRay Incorporated
    Inventors: Shmaryu M. Shvartsman, Gordon D. DeMeester, John L. Patrick, James F. Dempsey
  • Publication number: 20140340082
    Abstract: A core sample holder assembly for performing a laboratory magnetic resonance measurement of a core sample taken from a hydrocarbon containing formation is provided. The assembly comprises a pressure chamber provided by a hull and one or more flanges are sealingly coupled with the hull. A flexible core sample holder sleeve is arranged within the pressure chamber and is sealingly coupled with at least one of the flanges. An overburden fluid injection port is in fluid communication with an annular space between the hull and the flexible sleeve and is configured to inject overburden fluid into an annular space between the hull and the flexible sleeve. A pressure regulator is configured to maintain the overburden fluid in the annular space at an elevated pressure. A radio-frequency antenna, within the pressure chamber and wrapped around the sample holder sleeve, is configured to receive an electromagnetic-signal from the core sample. In use, the core sample is arranged substantially within the sleeve.
    Type: Application
    Filed: May 14, 2013
    Publication date: November 20, 2014
    Applicant: Chevron U.S.A. Inc.
    Inventors: Zheng YANG, Boqin SUN, John S. ZINTSMASTER, Gerald Latorraca, Ajit R. Pradhan
  • Publication number: 20140312901
    Abstract: A nuclear magnetic resonance (NMR) sample analyzer has a plurality of NMR units arrayed in a predetermined relationship to each other. Each of the NMR units includes a sample chamber having a sensitive volume for containing a sample to be analyzed; a radio frequency (RF) transmitting and receiving device proximal the sample chamber; and a magnet surrounding the RF transmitting and receiving device and sample chamber for generating a substantially uniform magnetic field within the sensitive volume and substantially no magnetic field beyond an outside wall of the magnet.
    Type: Application
    Filed: March 1, 2013
    Publication date: October 23, 2014
    Applicant: Halliburton Energy Services, Inc.
    Inventors: Songhua Chen, Rebecca Corina Jachmann
  • Publication number: 20140295486
    Abstract: A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.
    Type: Application
    Filed: March 26, 2014
    Publication date: October 2, 2014
    Applicant: STC.UNM
    Inventors: Laurel Sillerud, Todd M. Alam, Andrew F. McDowell
  • Patent number: 8843192
    Abstract: A breast coil arrangement for magnetic resonance applications has a placement web that allows an examination subject to lie with her sternum on the placement web with each breast in a receptacle respectively on opposite sides of the placement web. The breast receptacles have limiting elements whose spacing from one another can be adjusted. Multiple array coils are respectively arranged in the limiting elements and are stationary relative to the limiting elements. Each breast receptacle is surrounded by a volume coil that is stationary relative to the placement web. The volume coils are arranged centrally and orthogonally relative to the array coils and surround the array coils. The volume coils are decoupled from the array coils. A spectroscopy phantom can be arranged in proximity to the placement web.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: September 23, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventors: Christian Geppert, Rainer Kurth, Titus Lanz, Florian Odoj, Silke Quick, Christian Schuster, Alexander Weisser, Tobias Wichmann
  • Publication number: 20140266194
    Abstract: Methods for measuring physico-chemical properties using a nuclear magnetic resonance spectrometer are disclosed, including methods to determine an initial amount of a substance, usually a liquid, contained inside a porous material and an initial amount of the substance, usually a liquid, present outside the porous material, methods to measure the release kinetics of a substance, such as a liquid, from a porous material, and methods for performing chemical reactions and other physico-chemical operations in situ inside a nuclear magnetic resonance probe after a sample is loaded into a nuclear magnetic resonance spectrometer. The apparatuses for performing these methods are also disclosed.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: Robert Corkery, Chris Dimelow, Sergey V. Dvinskikh, Adam Feiler, Istvan Furo, Eapen George, Peter Given, Julie Anne Grover, Pavel V. Yushmanov
  • Publication number: 20140266196
    Abstract: The current disclosure describes an automated high-throughput small object sorting system for separating small object via oil and/or moisture content using novel nuclear magnetic resonance (NMR) systems and methods. The disclosed systems and methods for measuring the oil and/or moisture content of a single small object in a low-field time domain NMR instrument are superior in sample throughput and signal-to-noise ratio to conventional NMR systems and methods (free induction decay or spin echo) for single small object oil/moisture measurement.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Monsanto Technology LLC
    Inventors: Bin Dai, Susan Macisaac, Kevin L. Deppermann, Mark Ehrhardt, Brad White, Wayne Brown, Paul Krasucki, Jemmi C. McDonald
  • Patent number: 8836334
    Abstract: This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: September 16, 2014
    Assignee: T2 Biosystems, Inc.
    Inventors: W. David Lee, David A. Berry
  • Publication number: 20140253116
    Abstract: A nuclear magnetic resonance (NMR) measurement system for high pressure and temperature measurements on fluids is disclosed. The system has a sensor assembly that includes a sample holder having a body formed from a non-magnetic metal and defining an interior cavity for receiving a fluid sample, a frame member disposed in the interior cavity of the sample holder, an antenna coil disposed in the interior cavity about the frame member, an inlet that allows the fluid sample to enter the interior cavity, an outlet that allows for the fluid sample to be flushed from the interior cavity, and a magnet assembly having a central bore in which the sample holder is disposed. Adjacent to the sample holder are pulsed field gradient coils for performing diffusion measurements. The system further includes pulse sequencer circuitry that supplies signals to the antenna coil.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 11, 2014
    Applicant: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Robert Freedman, Vivek Anand, Payam Tabrizi, Ricardo Y. Torres, Douglas W. Grant, Daniel Catina, Krishnamurthy Ganesan
  • Patent number: 8829904
    Abstract: A method of and miniaturized apparatus adapted for in-situ measurement of degradation of automotive fluids and the like by micro-electron spin resonance (ESR) spectrometry, wherein the use of a modulated constant magnetic field in an RF resonating variable frequency microwave cavity resonator through which a fluid sample is passed, enables direct detection of molecular changes in such fluid sample resulting from fluid degradation during use.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: September 9, 2014
    Assignee: Active Spectrum, Inc.
    Inventors: James R. White, Christopher John White
  • Publication number: 20140232406
    Abstract: When imaging a patient using a magnetic resonance (MR) imager, it is desirable to locate an radio frequency (RF) head coil at a position lower than the flat table top patient surface in order to optimize the geometry of the patient anatomy and the RF coil. A flat table top is provided for an MR patient support table (10) that includes a pocket or recessed portion (50) that accepts an RF head coil (14), thereby optimizing imaging geometry. When the RF coil is not mated to the recessed portion of the table (10) a filler insert (20) is mated therewith. This allows an operator to use the table top without the filler insert to position a neurovascular coil at an optimized location below the table top surface for brain imaging, as well as to convert the patient support table back to a completely flat top by removing the coil and installing the flat surface filler insert for additional positioning requirements.
    Type: Application
    Filed: September 20, 2012
    Publication date: August 21, 2014
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventor: Dennis K Everett
  • Publication number: 20140225611
    Abstract: A system for MRI imaging the near surface of tissue specimens wherein the volume of interest of the MRI is held substantially within the surface-proximate tissue of the specimen by means of some combination of maneuvering the specimen, maneuvering the MRI RF magnetic field magnet, maneuvering the MRI RF receiver coil, maneuvering the static field magnets, and reshaping the tissue.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 14, 2014
    Applicant: ASPECT IMAGING LTD.
    Inventor: Uri RAPOPORT
  • Publication number: 20140218032
    Abstract: In some aspects, a resonator device for spin resonance applications is described. In some examples, the resonator device includes a substrate, terminals, and resonators. The terminals include a first terminal having first terminal segments disposed on a substrate surface, and a second terminal having second terminal segments disposed on the substrate surface opposite the first terminal segments. The resonators include conductors disposed on the substrate surface between the first and second terminals. Each conductor is disposed between one of the first terminal segments and a respective, opposite one of the second terminal segments.
    Type: Application
    Filed: June 28, 2013
    Publication date: August 7, 2014
    Applicant: Quantum Valley Investment Fund LP
    Inventors: Hamidreza Mohebbi, David G. Cory
  • Publication number: 20140218030
    Abstract: A subject support (22) of a magnetic resonance (MR) system (10) includes a table top (20) supported by a support structure (24) and configured to move in and out of an examination volume (14). The subject support (22) further includes a coil connector (34) connected with a local receive coil (32). The coil connector (34) moves between an engaged position in which the coil connector (34) and the local receive coil (32) engage and move with the table top (20) in and out of the examination volume (14) and a disengaged position in which the coil connector (34) and the local receive coil (32) remain stationary out of the examination volume (14) as the table top (20) moves in and out of the examination volume (14).
    Type: Application
    Filed: August 23, 2012
    Publication date: August 7, 2014
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventor: Paul Royston Harvey
  • Patent number: 8773125
    Abstract: Methods and related apparatuses of a downhole micro nuclear magnetic resonance (NMR) device having a resonant tuning (LC) circuit for use in a formation for collecting NMR signals from a fluid in the formation while under downhole pressures and temperatures. The downhole micro NMR device includes: a micro tube for the flowing fluid to flow therethrough; at least one magnet disposed about the micro tube; and at least one micro RF coil structured and arranged approximate to the micro tube and tuned to a Larmor frequency corresponding to a applied magnetic field from the at least one magnet.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: July 8, 2014
    Assignee: Schlumberger Technology Corporation
    Inventors: Timothy Hopper, Martin Hurlimann, Yi-Qiao Song
  • Publication number: 20140184225
    Abstract: A patient table includes a table body configured for bearing a patient, a connecting rod structure configured for supporting the table body, and a spring structure. The connecting rod structure is operable such that the table body may perform a lifting motion between a high position and a low position. Both ends of the spring structure are fixed. At least a first end of the spring structure is hinged to the connecting rod structure. The spring structure may be used for driving the lifting motion of the connecting rod structure and/or bearing the table body. The patient table may be used for nuclear magnetic resonance imaging equipment.
    Type: Application
    Filed: December 30, 2013
    Publication date: July 3, 2014
    Inventors: Ting Qiang Xue, Xu Yan
  • Patent number: 8761861
    Abstract: A magnetic resonance imaging apparatus includes a magnet having a two poles and a wall connecting the poles; the poles delimiting a patient-imaging space; and a table which is slidably connected to one of the two poles between the two poles and which table extends substantially parallel to the two poles; a drive for displacing the table relative to the magnet; a lock for locking the table in a selected position relative to the magnet; a drive for rotating the magnet about the axis; the table connected to the magnet such that the table rotates with the magnet when the magnet rotates about the axis; the magnet and the table being rotatable from a position in which the poles and the table are horizontal to a position in which the table and the poles are vertical.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: June 24, 2014
    Assignee: Esaote S.p.A.
    Inventors: Luigi Satragno, Eugenio Biglieri, Fabio Rezzonico, Osvaldo Pugliese, Orfeo Contrada, Trequattrini Alessandro
  • Publication number: 20140167756
    Abstract: A magic-angle-spinning (MAS) nuclear magnetic resonance (NMR) probe is described that includes double containment enclosures configured to seal and contain hazardous samples for analysis. The probe is of a modular design that ensures containment of hazardous samples during sample analysis while preserving spin speeds for superior NMR performance and convenience of operation.
    Type: Application
    Filed: December 13, 2013
    Publication date: June 19, 2014
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Herman M. Cho, Nancy M. Washton, Karl T. Mueller, Jesse A. Sears, JR., Mark R. Townsend, James R. Ewing
  • Patent number: 8754646
    Abstract: A method is provided for acquiring multiple NMR response signal data in rapid succession for averaging NMR spectral data from a sample. The fluid sample is placed in a capillary that extends through the magnetic field of the NMR spectrometer, including through the center of the magnetic field to place a segment of the sample in the magnetic center. After the sample fluid, initially magnetized by the magnetic field, is activated to emit an NMR pulse signal, the fluid in the capillary is advanced rapidly to put another pre-magnetized segment of the sample fluid in the fluid center, acquiring an NRM pulse signal, and continuing the cycle until a desired number of NMR response data signals from the sample have been acquired. Those response data from multiple acquisitions are then averaged.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: June 17, 2014
    Assignee: Picospin, LLC
    Inventors: John C. Price, Charles Miller, Erick Winston
  • Publication number: 20140159719
    Abstract: A method of acquiring an image in an MRI system includes dividing a scannable region of an object into regions, determining a coil to be used for the divided regions, receiving signals from the determined coil via signal channels connected to the determined coil and grouped by using a switching device, and acquiring the image from the received signals.
    Type: Application
    Filed: April 8, 2013
    Publication date: June 12, 2014
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Hak-soo CHON
  • Patent number: 8736267
    Abstract: A method and apparatus for measuring a parameter of an object is disclosed. The object is placed within a vessel configured to contain the object via an opening in the vessel. A cover is placed over the opening. A securing device is used to secure the cover to the vessel. A measurement device is used to measure the parameter of the object at a raised pressure. The parameter can be a nuclear magnetic resonance parameter of the object. A fluid in the vessel can be heated to raise the pressure within the sealed vessel. In various embodiments, the securing device can be a second cover or a clamp, for example. The measured parameter can be used in determining a suitability of the object for use in downhole environments.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: May 27, 2014
    Assignee: Baker Hughes Incorporated
    Inventors: David Peter Gerrard, Omar H. Balcazar