Spray Drying And Cooling Of Slurry Or Suspension Patents (Class 34/372)
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Patent number: 12247784Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted to from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.Type: GrantFiled: January 12, 2024Date of Patent: March 11, 2025Assignee: Velico Medical, Inc.Inventors: Robert R. Andrews, Herman E. Snyder, William J. Merritt, Evan P. Ordway, Clair Strohl
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Patent number: 12187861Abstract: A cellulosic particle contains 90 parts by mass or more and 99.5 parts by mass or less of cellulose; and 0.5 parts by mass or more and 10 parts by mass or less of a cellulose derivative.Type: GrantFiled: November 9, 2022Date of Patent: January 7, 2025Assignee: FUJIFILM Business Innovation Corp.Inventors: Kenji Yao, Kazusei Yoshida, Ayu Naito, Yuko Iwadate, Takahiro Ishizuka, Tetsuya Taguchi, Hirokazu Hamano, Masahiro Oki, Hideaki Yoshikawa
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Patent number: 10870946Abstract: A whitening composition for fabric, in particular, unbleached cellulosic fiber-containing fabric is described. The composition includes a blue dye, a violet dye; and, optionally, a thickening agent; wherein the composition is free of bleaching agents and optical brighteners. A method of whitening a fabric using whitening compositions is also disclosed.Type: GrantFiled: October 17, 2018Date of Patent: December 22, 2020Assignee: Everyone's Earth Inc.Inventors: Nicole M. Richards, Thomas C. Kallish
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Patent number: 9068776Abstract: Methods for drying oil sand fine tailings treated to comprise flocculated fine tailings, by deposition and farming techniques, are provided. A deposition cell is provided with a sloped bottom surface and the flocculated fine tailings are deposited to undergo channelless advancement in the cell while allowing drainage of release water. When the deposit is uneven, the deposit may be plowed while wet for spreading and ensuring water release conditioning is imparted thereto, while avoiding over-shearing, and maintaining sufficient shear strength to allow standing. Once a dried upper crust forms, the deposit may be harrowed to break up the crust, expose wet regions there-beneath and create furrows in the standing deposit. The methods improve the dewatering and drying of mature fine tailings in oil sands.Type: GrantFiled: October 30, 2009Date of Patent: June 30, 2015Assignee: SUNCOR ENERGY INC.Inventors: Trevor Bugg, Jamie Eastwood, Adrian Peter Revington, Marvin Harvey Weiss, Patrick Sean Wells, Thomas Charles Hann, Stephen Joseph Young, Hugues Robert O'Neill
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Patent number: 9060937Abstract: A process for the production of a composition comprising a water-insoluble sartan which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble sartan, ii) a water soluble carrier, iii) a solvent for each of the sartan and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the sartan in the carrier.Type: GrantFiled: June 29, 2007Date of Patent: June 23, 2015Inventors: David John Duncalf, Andrew James Elphick, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
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Patent number: 9023572Abstract: A method for producing resin particles, including ejecting a liquid containing at least a resin in the form of droplets from a droplet ejecting unit having a plurality of holes provided in a part of a flow channel for feeding the liquid containing at least a resin, and drying and solidifying the ejected droplets so as to obtain the resin particles, while the ejected droplets are transported by a primary transport air flow flowing in the direction in which the droplets are ejected, wherein the ejected droplets are further transported by a secondary transport air flow which transports the ejected droplets in a different direction from a direction in which the primary transport air flow flows, and wherein a smaller angle of angles formed between a velocity vector of the primary transport air flow and a velocity vector of the secondary transport air flow is less than 120 degrees.Type: GrantFiled: May 21, 2010Date of Patent: May 5, 2015Assignee: Ricoh Company, Ltd.Inventors: Takahiro Honda, Yohichiroh Watanabe, Yasutada Shitara, Yoshihiro Norikane
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Patent number: 8984765Abstract: A process for producing dispersion powders by spray drying of aqueous polymer dispersions and addition of antiblocking agents in a rotary atomization dryer, wherein the antiblocking agent is conveyed by delivery air, wholly or partly, into an annular gap which is formed by a moulding arranged concentrically around the housing of the rotary atomizer, and which ends at a distance above the upper edge of the atomizer plate of the rotary atomizer.Type: GrantFiled: July 25, 2012Date of Patent: March 24, 2015Assignee: Wacker Chemie AGInventors: Michael Herbert, Jochen Ring, Stefan Killat, Bernd Gerstenberger
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Patent number: 8966783Abstract: Provided are a novel vacuum-pressure spray-drying method and a novel vacuum-pressure spray-drying apparatus suitable for drying and powdering a liquid raw material containing a substance susceptible to heat denaturation, such as a food raw material and a medicine raw material.Type: GrantFiled: July 27, 2011Date of Patent: March 3, 2015Assignee: Tanabe Engineering CorporationInventors: Yutaka Kitamura, Kazuhiko Yamazaki, Yoshitsugu Yamano
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Patent number: 8828443Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.Type: GrantFiled: December 26, 2012Date of Patent: September 9, 2014Assignee: Bend Research, Inc.Inventors: Ronald A. Beyerinck, Heather L. M. Diebele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
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Publication number: 20140237847Abstract: A process for producing dispersion powders by means of spray drying of aqueous polymer dispersions and addition of antiblocking agents in a rotary atomization dryer, wherein the antiblocking agent is conveyed by means of delivery air, wholly or partly, into an annular gap which is formed by a moulding arranged concentrically around the housing of the rotary atomizer, and which ends at a distance above the upper edge of the atomizer plate of the rotary atomizer.Type: ApplicationFiled: July 25, 2012Publication date: August 28, 2014Applicant: Wacker Chemle AGInventors: Michael Herbert, Jochen Ring, Stefan Killat, Bernd Gerstenberger
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Patent number: 8569430Abstract: Methods for producing spray-dried phenol-formaldehyde resole resins and products made therefrom. The method can include spray-drying an aerated liquid phenol-formaldehyde resole resin containing about 0.02 wt % or more of a surfactant, based on a combined weight of the liquid phenol-formaldehyde resole resin and the surfactant, to produce a spray-dried phenol-formaldehyde resole resin powder.Type: GrantFiled: December 9, 2010Date of Patent: October 29, 2013Assignee: Georgia-Pacific Chemicals LLCInventors: James H. Knight, Paul S. Baxter, Robert M. Meacham, John D. Cothran
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Patent number: 8343550Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.Type: GrantFiled: June 21, 2011Date of Patent: January 1, 2013Assignee: Bend Research, Inc.Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
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Patent number: 8176655Abstract: A vapor atmosphere spray dryer can include a closed-loop circuit having a dryer, a bag house filter system, a fan, and a heater system which are fluidly connected together for circulating a mass of superheated vapor therethrough. A centrifugal atomizer is disposed within the dryer. A feed system delivers a supply of feed slurry to the centrifugal atomizer which discharges a supply of atomized feed slurry in the dryer for combination with the circulated mass of superheated vapor within the dryer. The closed loop circuit is constructed such that the circulated mass of superheated vapor has an operating pressure of at least 1 psi which is generated by the evaporation of the fluid in the atomized feed slurry in the dryer resulting from the combination of the supply of atomized feed slurry and the circulated mass of superheated vapor.Type: GrantFiled: December 16, 2008Date of Patent: May 15, 2012Assignee: SPX Flow Technology Danmark A/SInventor: Stewart Gibson
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Publication number: 20110277339Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.Type: ApplicationFiled: June 21, 2011Publication date: November 17, 2011Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
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Patent number: 7988074Abstract: Apparatus and methods for the dispersion of material into a drying gas stream are disclosed. The material dispersion apparatus can have a nozzle and a venturi positioned downstream of the nozzle. The drying gas stream can be generated by pulse combustion dryer or by spray dryer and pass over at least a portion of the nozzle.Type: GrantFiled: March 5, 2009Date of Patent: August 2, 2011Assignee: J. Jireh Holdings LLCInventor: David A. Mirko
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Publication number: 20110062630Abstract: With regard to compositions derived from active ingredients and other additives in medical, food and industrial fields, there have been problems that the active ingredients cannot be uniformly mixed, and that the active ingredients become segregated and lose uniformity as the active ingredients undergo transport, input, and filling processes. There is provided a cellulose powder which improves the uniformity of compositions containing active ingredients or other additives to prevent segregation of the active ingredients, wherein the cellulose powder contains cellulose I type crystals, has an average particle diameter of less than 30 ?m, a powder density of 0.1 to 0.45 g/cm3, a tapping density of 0.1 to 0.5 g/cm3, a repose angle of 35 to 50°, a specific surface of more than or equal to 0.1 m2/g and less than 20 m2/g, an internal friction angle of 36 to 42°, and is a cellulose powder including a secondary flocculation structure in which primary particles are flocculated.Type: ApplicationFiled: May 21, 2009Publication date: March 17, 2011Applicant: ASAHI KASEI CHEMICALS CORPORATIONInventors: Yosuke Honda, Kazuhiro Oobae
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Patent number: 7846372Abstract: The present invention provides a method of making a candle from a vegetable oil-based candle wax that provides a smooth, solid vegetable oil-based candle having fully integrated color and fragrance.Type: GrantFiled: April 30, 2004Date of Patent: December 7, 2010Assignee: SoyBasics, LLCInventors: Donald James Njus, Jon Nicolaisen
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Patent number: 7814679Abstract: An abrasive is fabricated to obtain sliding and grinding effects. In the abrasive, grinding particles are wrapped by a wrapping material. Various sizes and shapes of molds and micro components can be finely polished to obtain mirror-grade surfaces.Type: GrantFiled: April 21, 2008Date of Patent: October 19, 2010Assignee: National Central UniversityInventors: Biing-Hwa Yan, Feng-Che Tsai, Li-Wen Sun
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Publication number: 20100146807Abstract: A vapor atmosphere spray dryer can include a closed-loop circuit having a dryer, a bag house filter system, a fan, and a heater system which are fluidly connected together for circulating a mass of superheated vapor therethrough. A centrifugal atomizer is disposed within the dryer. A feed system delivers a supply of feed slurry to the centrifugal atomizer which discharges a supply of atomized feed slurry in the dryer for combination with the circulated mass of superheated vapor within the dryer. The closed loop circuit is constructed such that the circulated mass of superheated vapor has an operating pressure of at least 1 psi which is generated by the evaporation of the fluid in the atomized feed slurry in the dryer resulting from the combination of the supply of atomized feed slurry and the circulated mass of superheated vapor.Type: ApplicationFiled: December 16, 2008Publication date: June 17, 2010Applicant: Anhydro Inc.Inventor: Stewart Graham Gibson
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Publication number: 20100101107Abstract: According to a method for drying fuels in the form of dust, particularly to be fed to a gasification process, such as coal, petroleum coke, biological waste, or the like, wherein the fuel (1) is crushed in a mill (2) and fed to a filter/separator (3) by means of a propellant and drying gas, and at least part of the propellant/drying gas in the circuit is returned to the mill (2) after heating, the known disadvantages are not only to be avoided, but particularly a cost-effective milling and drying method and a corresponding system are to be provided, having low emissions and a low inert gas requirement. This is achieved according to the method in that part of the propellant/drying gas flow is cooled down and dehumidified in a spray tower (6), or the like, wherein part of the dried gas exiting the spray tower is fed to the environment and/or a firing process, and the other part is returned to the propellant/drying gas flow.Type: ApplicationFiled: December 14, 2007Publication date: April 29, 2010Applicant: Uhde GmbHInventors: Johannes Kowoll, Eberhard Kuske
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Patent number: 7531131Abstract: A method using vibration for conditioning, air-conditioning, cooling and decontaminating, disinfecting and sterilizing physical media. The method includes a first vibratory action (13) performed on a regulated incoming current of the physical medium (2) so that the flow of the physical medium (2) is formed and the necessary and adequate conditions for cooling are created; a refrigerating medium (3) and a cold-absorbing medium (6) interact in a heat exchanging system (1); and another vibratory action (10) is performed on a cold-absorbing medium in order that the physical medium is continuously and/or periodically decontaminated and the necessary and adequate conditions for the functioning of the decontamination system in its steady state are created.Type: GrantFiled: December 7, 2000Date of Patent: May 12, 2009Inventors: Danil Doubochinski, Roman Prytkov
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Process for preparing certain hydrohalide metal complex compounds having a specific coarse structure
Patent number: 7523563Abstract: The present invention relates to a process for preparing a granular hydrohalide salt of a particular metal complex compound which is composed of a divalent metal cation as central ion and of an amino dicarboxylic acid ion and, where appropriate, water as ligand, where the hydrohalide salt is obtained with a specific particle size distribution.Type: GrantFiled: August 18, 2005Date of Patent: April 28, 2009Assignee: Verla-Pharm Arzneimittelfabrik Apotheker H.J.v. Ehrlich GmbH & Co. KGInventor: Guenter Hopf -
Patent number: 7469488Abstract: Spray dried particles having specified aerodynamic characteristics are produced by atomizing a liquid feed and contacting the liquid feed with a drying gas, such as, for example, air or nitrogen. The humidity of the drying gas is controlled to a value, expressed, for instance, as dew point, which is known to produce particles having a specified tap density or aerodynamic diameter. Particles having a volume median geometric diameter greater than about 5 microns and a tap density less than about 0.4 g/cm3 are preferred.Type: GrantFiled: October 29, 2004Date of Patent: December 30, 2008Assignees: Alkermes, Inc., The Penn State Research FoundationInventors: Donghao Chen, Richard P. Batycky, Lloyd Johnston, Jeffrey Mintzes
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Patent number: 7181862Abstract: Glassy articles are prepared by subjecting to hydrolysis and policondensation a solution or suspension of a suitable precursor, mainly comprising a silicon alkoxide, and by drying the obtained gel in a pressure chamber, the gel solvent having been substituted by a non-protic solvent, mainly acetone, under nitrogen flowing, at temperature and pressure conditions lower than the gel solvent critical values. The dried gel is then densified by a thermal treatment.Type: GrantFiled: December 23, 2003Date of Patent: February 27, 2007Assignee: Degussa Novara Technology, S.p.A.Inventors: Giulio Boara, Massimo Sparpaglione, Lorenzo Costa
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Patent number: 7144931Abstract: A method of manufacturing polymer particles capable of increasing the easiness of handling of powder when the powder is collected and preventing the powder from adhering to the wall surface of a dryer and the outlet of the dryer from being clogged with the powder by suppressing the occurrence of ruptured particles to reduce the produced amount of the fine powder when polymer particles are produced by spraying and drying polymer latex, characterized in that, when the polymer latex having a minimum film forming temperature of 50° C. or higher is sprayed and dried with heating gas for drying in the dryer, the temperature of the heating gas for drying at the dryer outlet is less than the temperature obtained by adding 15° C. to the minimum film forming temperature of the polymer latex, the wet-bulb temperature thereof at the dryer outlet is higher than the temperature obtained by deducing 30° C.Type: GrantFiled: May 17, 2002Date of Patent: December 5, 2006Assignee: Mitsubishi Rayon Co., Ltd.Inventors: Masaki Omote, Akihiro Toritani, Daisuke Shiramizu, Hiroyuki Iyota
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Patent number: 7118764Abstract: The subject of the present invention is a process for preparing pregelatinized high amylose starch, comprising the steps consisting of: forming a suspension comprising a high amylose starch and water; subjecting the said suspension to steam jet cooking at a temperature of between 125 and 135° C. so as to obtain a pregelatinized high amylose starch paste; cooking and drying the said pregelatinized starch paste on a drum dryer at a pressure of between 2 and 10 bar, so as to obtain a pregelatinized high amylose starch. Its subject is also a pregelatinized high amylose starch, having an apparent density of less than 0.4 g/ml for a mean particle size of 100 micrometers. Its subject is in addition the use of such a starch for the manufacture of soft gelatin capsules or of hard gelatin capsules and the film-coating of pharmaceutical, dietary or agricultural solid forms.Type: GrantFiled: March 25, 2002Date of Patent: October 10, 2006Assignee: Roquette FreresInventors: Domenico Carbone, Claude Quettier, Giovanni Semino, Ernesto Fossati
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Patent number: 6973741Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.Type: GrantFiled: January 27, 2004Date of Patent: December 13, 2005Assignee: Pfizer, Inc.Inventors: Ronald A. Beyerinck, Heather L. M. Diebele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
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Patent number: 6870071Abstract: Processes for preparing alkali metal alkoxide granules and alkaline earth metal alkoxide granules of aliphatic, saturated or unsaturated, unbranched or branched alcohols, preferably having 1 to 12, in particular 1 to 6, carbon atoms. A preferred process for preparing the alkoxides utilizes fluidized-bed spray granulation.Type: GrantFiled: October 15, 2002Date of Patent: March 22, 2005Assignee: Degussa AGInventors: Joachim Luethi, Stefan Schulze, Christian Alt, Andreas Goelz, Andreas Harthun
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Patent number: 6848197Abstract: Spray dried particles having specified aerodynamic characteristics are produced by atomizing a liquid feed and contacting the liquid feed with a drying gas, such as, for example, air or nitrogen. The humidity of the drying gas is controlled to a value, expressed, for instance, as dew point, which is known to produce particles having a specified tap density or aerodynamic diameter. Particles having a volume median geometric diameter greater than about 5 microns and a tap density less than about 0.4 g/cm3 are preferred.Type: GrantFiled: April 18, 2001Date of Patent: February 1, 2005Assignees: Advanced Inhalation Research, Inc., The Penn State Research Foundation, Inc.Inventors: Donghao Chen, Richard P. Batycky, Lloyd Johnston, Jeffrey Mintzes
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Patent number: 6845571Abstract: The invention can relate to a fluidized bed apparatus with an integrated spray-drying device and to a method for using the same. The invention also can relate to a method for producing a spray-dried powder material, whose product characteristics can be specifically adapted according to the ulterior use of the material.Type: GrantFiled: June 6, 2000Date of Patent: January 25, 2005Assignee: Merck Patent GmbHInventors: Eugen Schwarz, Gernot Moeschl, Hanspeter Ruetzler, Jean-Marc Dutter
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Patent number: 6829843Abstract: The present invention provides a process for preparing vinylpyrrolidone polymer powder, which has high bulk density and favorable powder flowability and can be handled with ease. Specifically, the present invention relates to a process for preparing vinylpyrrolidone polymer powder, which comprises spraying an aqueous solution of a vinylpyrrolidone polymer into a drying tower using a disc atomizer and then drying.Type: GrantFiled: January 8, 2004Date of Patent: December 14, 2004Assignee: Dai-Ichi Kogyo Seiyaku Co., Ltd.Inventor: Keiichi Fujise
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Patent number: 6769200Abstract: An apparatus and method for the spray drying of solvent-containing compositions. A liquid or paste-form solvent-containing composition is heated to a temperature above the boiling point of the solvent, transported under excess pressure and at a temperature above the boiling point of the solvent to a relaxation space where it is sprayed to evaporate the solvent. The relaxation space is not under excess pressure and is at a temperature that is above the boiling point of the solvent.Type: GrantFiled: November 4, 2002Date of Patent: August 3, 2004Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Wilfried Raehse, Ovidiu Dicoi, Peter Walzel
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Patent number: 6763607Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.Type: GrantFiled: January 28, 2003Date of Patent: July 20, 2004Assignee: Pfizer Inc.Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
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Patent number: 6754979Abstract: An apparatus (1) is proposed for drying and heat-treating pellets with a stream of inert gas, wherein the apparatus has a cuboid base unit (2) with a feed (3) for the pellets in its upper part and an outlet (4) in its lower part, with a feed (5) on one lateral surface and with an exhaust base (6) on the opposite lateral surface of the cuboid base unit (2) for the stream of inert gas, and also with distribution and retention equipment (7, 8) in the region of the feed (5) and, respectively, of the exhaust (6) for the stream of inert gas, where each of these extends essentially over the entire vertical cross section of the cuboid base unit (2).Type: GrantFiled: May 16, 2002Date of Patent: June 29, 2004Assignee: BASF AktiengesellschaftInventors: Alfons Ludwig, Ragnhild Pille, Gunter Pipper
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Patent number: 6712215Abstract: A method of solvent recovery from oil sand extraction plant tailings, using 180 degree opposing steam-assisted accelerating nozzles, impacting on each other's high velocity jets, thus creating an impact area at the point of collision, creating an exceedingly large number of small droplets having a very large surface area exposed to the depressurized environment inside the vessel in which the nozzles are mounted. The diluent thus escaping from the tiny droplets is collected from the vessel space and recovered by condensation in a surface condensor and returned to the process.Type: GrantFiled: July 16, 2001Date of Patent: March 30, 2004Inventor: Adolf Frederik Scheybeler
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Patent number: 6711831Abstract: In a compact combined spray drying and after-treatment apparatus having internal gas filters and an internal fluidized bed in the drying chamber and a fluidized bed in the after-treatment zone, pipe means are used for conducting a stream of particle-loaded gas formed in the after-treatment zone to suitable locations in the drying chamber without disturbing the normal operation of the drying chamber and the fluidized bed therein.Type: GrantFiled: February 15, 2000Date of Patent: March 30, 2004Assignee: Niro A/SInventors: Ove Emil Hansen, Jens Mourits Sørensen, Martin Andreas Grønlund Scholten, Eric Franzen
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Thermosetting powder coating composition, method of preparation thereof and coated article therewith
Patent number: 6649267Abstract: A thermosetting powder coating composition has an average particle diameter of entire particles is within a range from 5 to 50 &mgr;m, an average circularity of the particles is 0.90 or more, and a circularity of particles having a maximum number frequency in circularity distribution is within a range from 0.98 to 1.00, prepared by spray-drying an organic solvent solution containing, as a coating film forming component, an epoxy group-containing vinyl copolymer (A) having a glass transition temperature of 40° C. or higher, an epoxy group-containing vinyl copolymer (B) having a glass transition temperature of 0° C. or lower and a polycarboxylic acid (C) as an essential component.Type: GrantFiled: June 11, 2002Date of Patent: November 18, 2003Assignees: Dainippon Ink and Chemicals, Inc., Liquid Gas Co., Ltd.Inventors: Tetsuro Agawa, Katsuhiko Okada, Hiroo Tanaka, Masaya Hashimoto, Takaaki Asakura -
Publication number: 20030200672Abstract: Systems and methods for processing a high-lactose aqueous fluid (HLAF), such as permeate from ultrafiltration of whey fluid, are described. The preferred process includes concentrating HLAF containing from about 1 to about 35% solids, wherein at least 50% of the solids are lactose, to form a concentrated HLAF containing from about 45 to about 65% solids; further concentrating the HLAF to form a highly concentrated HLAF containing from about 70 to about 80% solids; cooling the highly concentrated HLAF with a gaseous fluid to create a cooling, concentrating, crystallizing cascade to further concentrate the HLAF to form a partially crystallized HLAF containing from about 78 to about 88% solids; and drying the partially crystallized HLAF in an air-lift dryer to form a product rich in crystalline alpha-lactose monohydrate. An air-lift dryer having diverging sidewalls and methods of using same are also disclosed.Type: ApplicationFiled: March 3, 2003Publication date: October 30, 2003Inventor: A. Kent Keller
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Publication number: 20030163931Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.Type: ApplicationFiled: January 28, 2003Publication date: September 4, 2003Inventors: Ronald A. Beyerinck, Heather L.M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
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Publication number: 20030088994Abstract: Processes for preparing alkali metal alkoxide granules and alkaline earth metal alkoxide granules of aliphatic, saturated or unsaturated, unbranched or branched alcohols having 1 to 12, in particular 1 to 6, carbon atoms. A preferred process for preparing the alkoxides utilizes fluidized-bed spray granulation.Type: ApplicationFiled: October 15, 2002Publication date: May 15, 2003Applicant: Degussa AGInventors: Joachim Luethi, Stefan Schulze, Christian Alt, Andreas Goelz, Andreas Harthun
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Patent number: 6560897Abstract: Improved spray drying apparati, and methods of use thereof, have been developed. The spray drying equipment includes a primary drying chamber and a secondary drying apparatus which includes tubing having a length sufficient to increase the contact time between the drying gas and the droplets/particles to dry the particles to the extent desired, at a drying rate and temperature which would be too low to provide adequate drying without the secondary drying apparatus. The secondary drying apparatus increases the drying efficiency of the spray dryer system without increasing the drying rate, while minimizing loss in yield. Te secondary drying apparatus can include multiple secondary apparati, which are independently controlled for temperature and/or have different dimensions (cross-sectional areas and/or lengths), to allow for optimization of drying conditions.Type: GrantFiled: October 26, 2001Date of Patent: May 13, 2003Assignee: Acusphere, Inc.Inventors: Donald E. Chickering, III, Mark J. Keegan, Greg Randall, Howard Bernstein, Julie Straub
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Patent number: 6463675Abstract: In a spray drying process utilizing a spray dryer having internal gas filters and an internal fluidized bed and comprising an after-treatment of the product in a separate unit outside the spray drying chamber, which treatment produces a particle-loaded gas stream, said particle-loaded gas stream is conducted from the separate unit to the spray drying chamber. The stream passes, together with the spent drying gas in the drying chamber, the filters integrated in said chamber. Several plant modifications are suggested for performing the process which involves substantial savings by making external particle collectors superfluous.Type: GrantFiled: September 29, 1999Date of Patent: October 15, 2002Assignee: Niro A/SInventors: Ove Emil Hansen, Jens Mourits Sørensen, Martin Andreas Grønlund Scholten
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Publication number: 20020056206Abstract: The present invention relates to a novel spray drying process for the preparation of pharmaceutical compositions containing small particles of phospholipid-stabilized fenofibrate. This invention also relates to spray dried powdered compositions prepared according to this process, and to dosage forms of fenofibrate (capsules, tablets, powders, granules, and dispersions) prepared from these powdered compositions. The powdered compositions and dosage forms are useful in the treatment of dyslipidemia and dyslipoproteinemia and have the advantage that they provide reduced in vivo variability in the bioavailability of fenofibrate active species among fed and fasted patients when administered orally.Type: ApplicationFiled: April 20, 2001Publication date: May 16, 2002Inventors: Gary W. Pace, Awadesh K. Mishra, Robert A. Snow, Indu Parikh, Pol-Henri W. Guivarc'h
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Patent number: 6328099Abstract: Free-flowing solid particles are dried in a moving bed dryer by passing the particles adjacent to a heat exchanger plate containing a heated fluid while passing a dehumidified gas into the solid particles from a gas flow manifold in the heat exchanger plate.Type: GrantFiled: April 21, 1999Date of Patent: December 11, 2001Assignee: Mississippi Chemical CorporationInventors: George Allen Hilt, Donald Ray Thomas
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Patent number: 6308434Abstract: Improved spray drying methods of have been developed. The spray drying method includes use of a primary drying chamber and a secondary drying apparatus which includes tubing having a length sufficient to increase the contact time between the drying gas and the droplets/particles to dry the particles to the extent desired, at a drying rate and temperature which would be too low to provide adequate drying without the secondary drying apparatus. The secondary drying apparatus increases the drying efficiency of the spray dryer system without increasing the drying rate, while minimizing loss in yield. The ratio of the length of tubing to the length of the primary drying chamber is at least 2:1. The tubing diameter is substantially smaller than the diameter of the primary drying chamber, such that the particles move at higher velocity through the tubing to minimize product losses.Type: GrantFiled: January 9, 2001Date of Patent: October 30, 2001Assignee: Acusphere, Inc.Inventors: Donald E. Chickering, III, Mark J. Keegan, Greg Randall, Howard Bernstein, Julie Straub
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Patent number: 6237247Abstract: A spray dryer apparatus and method suitable for the production of detergents, cleaners and components thereof wherein the inner wall of the drying chamber is provided with an air-permeable textile material lining at a distance from the inner wall, and at least one outlet for compressed gas is provided between the inner wall and the textile material lining whereby adherence of sticky deposits on the inner wall of the drying chamber is avoided or reduced.Type: GrantFiled: June 9, 1998Date of Patent: May 29, 2001Assignee: Henkel Kommanditgesellschaft auf AktienInventor: Jan Van Den Meersche
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Patent number: 6023855Abstract: The invention provides an air-assisted wiping device for use in a continuous-spray dryer. The air-assisted wiping device rotates inside the housing to continuously wipe heavy sticky powder from the walls of the housing using a wiper blade. The air-assisted wiping device includes an elongated hollow plenum having a flow-directing slot disposed along its length. Air received into the elongated hollow plenum is passed through the flow-directing slot onto a wiper blade, which is coupled to the elongated hollow plenum. The air discharged onto the wiper blade removes powder that collects on the leading side of the wiper blade.Type: GrantFiled: November 27, 1996Date of Patent: February 15, 2000Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Neil M. Goldberg, Charles I. Onwulata, Philip Wayne Smith, Greg Tomes
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Patent number: 5996247Abstract: Apparatus and method for condensing moisture from an air stream. The condensing comprises an outer container, a middle container within the outer container, and an inner container within the middle container. The outer container contains a cooling material, such as water, and upon contact therewith, the air stream is cooled and moisture contained therein is condensed. The inner container also can contain a cooling material.Type: GrantFiled: March 9, 1999Date of Patent: December 7, 1999Assignee: Big Beans Holding Ltd.Inventor: Nobuyoshi Kuboyama
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Patent number: 5849862Abstract: Processes for spray drying water-soluble and water-swellable vinyl-addition polymer-containing dispersions, emulsions and microemulsions to obtain substantially dry water-soluble or water-swellable polymer particles, compositions of substantially dry water-soluble or water-swellable polymer particles, methods of agglomerating spray-dried polymer particles, and methods of using spray-dried polymer particles and agglomerates in water-treating, mining, paper, food processing, soil conditioning, solution thickening, biotechnological, and oil recovery applications are disclosed.Type: GrantFiled: June 21, 1996Date of Patent: December 15, 1998Assignee: Cytec Technology Corp.Inventors: William Bloor Davies, John Edward Healy, Gary Kaui Lani Miller, Joseph J. Kozakiewicz
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Patent number: 5700471Abstract: Process for the production of fine-particle, essentially amorphous dye or drug preparations by converting a relatively coarse-particle dispersion or a solution into a colloidal dispersion in water, where the colloidal dispersion is generated at a temperature above the melting point of the dye or drug by admixing appropriately hot water (where appropriate under pressure) or an aqueous protective colloid solution so that an emulsion of a melt in aqueous medium is produced and is immediately spray-dried or converted by cooling into a suspension.Type: GrantFiled: December 18, 1995Date of Patent: December 23, 1997Assignee: BASF AktiengesellschaftInventors: Lutz End, Dieter Horn, Erik Lueddecke