Abstract: The present disclosure provides methods and systems for ghost cytometry (GC), which may be used to produce an image of an object without using a spatially resolving detector. This may be used to perform image-free ultrafast fluorescence “imaging” cytometry, based on, for example, a single pixel detector. Spatial information obtained from the motion of cells relative to a patterned optical structure may be compressively converted into signals that arrive sequentially at a single pixel detector. Combinatorial use of the temporal waveform with the intensity distribution of the random or pseudo-random pattern may permit computational reconstruction of cell morphology. Machine learning methods may be applied directly to the compressed waveforms without image reconstruction to enable efficient image-free morphology-based cytometry.

Abstract: Aspects of the present disclosure include flow cytometers configured to compensate for optical noise caused by operational change of a laser. Flow cytometers according to certain embodiments include a laser assessor configured to assess operational change of a laser. In embodiments, the laser assessor includes a reference detector and a mirror positioned between the reference detector and the flow cell that is configured to reflect forward scattered light to a forward scatter detector and allow non-scattered laser light to pass through to the reference detector. Methods for assessing laser functionality and, where desired, dynamically adjusting flow cytometer data, based on laser reference data from the laser assessor are also provided.

Abstract: An optical system is provided which comprises: a light source (1) for emitting light beam; an optical main axis; an optical shaping element (2) for shaping a light beam facing the light source (1) and directly adjacent to the light source (1), wherein the optical shaping element (2) includes a first freeform surface facing the light source (1), the light beam is shaped by means of the first freeform surface of the optical shaping element (2) in such a way that light intensity of the light beam has a flat-top profile on a first axis which is perpendicular to the optical main axis. With this optical system, a desirable light intensity profile can be achieved by using only a single optical element. Moreover, a flow cytometer including this optical system is provided.

Abstract: Example computer-implemented methods and systems for anomaly-sensing based multi-agent navigation are disclosed. One example computer-implemented method includes: receiving relative distance data specifying distance between at least one pair of agents of a plurality of agents, each of a first subset of the plurality of agents having an anomaly sensor subsystem; determining a set of relative pose vectors based at least in part on the relative distance data; receiving anomaly data from at least one anomaly sensor subsystem of one of the plurality of agents, obtaining pre-surveyed map data; determining global pose data of the plurality of agents based on the relative distance data and based on comparing the anomaly data to the pre-surveyed map data; and assigning a task to at least one of the plurality of agents based at least in part on a specialized operational capability of the at least one of the plurality of agents.

Abstract: A flow cell includes a flow cell body. The flow cell body includes a frame and a fluid chamber defined in the flow cell body. The fluid chamber includes a reaction region allowing a fluid flow. A liquid inlet, a liquid outlet, and two exhaust holes connected to the fluid chamber are in the frame. Fluid into the liquid inlet flows through the reaction region in the fluid chamber and flows out through the liquid outlet. The exhaust holes discharge gas generated in the fluid chamber during the fluid flow. A flow cell with integral sealing rings and a biochemical substance reaction device are also disclosed.

Abstract: A flow cytometer capable of easily and reliably providing flow cytometry results without requiring a special trained technician is provided. The flow cytometer 10 includes an input unit 60 that receives an input of information for specifying a measurement item, a condition selection unit 71 for selecting a measurement condition from among one or a plurality of measurement conditions corresponding to information for specifying the measurement item received by the input unit 60, and a measurement unit 65 having a flow cell 20 through which a particle-containing liquid containing particles in the sample passes, wherein the measurement unit 65 optically measures particles of the particle-containing liquid flowing through the flow cell 20 in accordance with the measurement condition selected by the condition selection unit 71.

Abstract: A device for producing fluorine gas has a first flow path configured to send a fluid from the inside of an electrolytic cell through a mist removal unit configured to remove mist from the fluid to a fluorine gas selection unit and a second flow path configured to send the fluid from the inside of the electrolytic cell to the fluorine gas selection unit without passing through the mist removal unit and has a flow path switching unit configured to switch a flow path through which the fluid flows depending on the average particle size of the mist measured by an average particle size measurement unit. The second flow path has a clogging suppression mechanism configured to suppress clogging of the second flow path by the mist.

Abstract: The present application discloses a method of determining one or more fuel characteristics of an aviation fuel suitable for powering a gas turbine engine of an aircraft. The method comprises: determining, during use of the gas turbine engine, one or more exhaust content parameters by performing a sensor measurement on an exhaust of the gas turbine engine; and determining one or more fuel characteristics of the fuel based on the one or more exhaust parameters including the nvPM content of the exhaust. Also disclosed is a fuel characteristic determination system, a method of operating an aircraft, and an aircraft.

Abstract: Provided is a technique for preventing erroneous recognition of a fine particle region from a captured image of fine particles. A fine particle testing apparatus of the present disclosure includes: an imaging part capturing a first fine particle image of a well that holds a liquid containing fine particles; an image processor executing a process of generating a second fine particle image by extracting a contour of the first fine particle image, a process of performing a logical operation between the first fine particle image and the second fine particle image, a process of calculating a feature amount of the fine particles based on a result of the logical operation, and a process of determining growth of the fine particles in the well based on the calculated feature amount; and an output part outputting a result of the determination.

Abstract: A mineral processing system featuring a controller having a signal processor or processing module configured to: receive signaling containing information about a relationship between multiple particle size measurements of different measured particles having different measured particle sizes flowing in a hydrocyclone classifier overflow stream sensed by at least one particle size measurement device arranged on a hydrocyclone classifier overflow pipe of at least one hydrocyclone in a hydrocyclone battery, and about a floatable fraction that defines a particle size range of different floatable particle sizes of different floatable particles that can be recovered by the at least one hydrocyclone in the hydrocyclone battery; and determine corresponding signaling containing information to control a ground product size of ore having ground particles provided to the at least one hydrocyclone in the hydrocyclone battery, based upon the signaling received.

Abstract: A detector system includes a droplet generator system, wherein the droplet generator system includes a droplet generator unit. The droplet generator unit is configured to create droplets from a liquid supplied to the droplet generator unit with a droplet generator liquid flow. The droplet generator unit is configured to create the droplets with a defined droplet generation frequency.

Abstract: Disclosed are an optical interferometry apparatus for detection of dielectric nanoparticles and a method for enhancing visibility of the nanoparticles. An imaging system for detection of dielectric nanoparticles includes at least one light source for illumination, a detector array or a camera for image capture, an objective lens, a sample substrate and a computing unit. The sample substrate is capable of carrying sub-wavelength particles smaller than the diffraction resolution limit of the imaging system, and the imaging system includes a movable means which moves the sample substrate in the axial direction such that depthwise different images are captured at different axial distances from the sample substrate to the objective lens. The computing unit computes a correlation image using the depth images wherein the sub-wavelength particles become resolvable and appear with higher contrast in the correlation image.

Abstract: The invention generally relates to detecting biological substances. In certain aspects, the invention is directed to a method directing one or more wavelengths of light within a deep ultraviolet (UV) spectrum into a medium to excite a biological substance in the medium, detect emission from the excited biological substance via a plurality of semiconductor photodetectors, and analyze the deep UV emission data for presence of a deep UV spectral signature indicative of the biological substance, wherein presence of the deep UV spectral signature indicates that the medium comprises a biological substance. The invention is also directed to identifying a pathogen in a medium comprising a pathogen and a non-pathogen biological substance.

Abstract: The present disclosure describes a computer implemented method, a system, and a computer program product of purifying a sample solution via real-time multi-angle light scattering. In an embodiment, the method, system, and computer program product include receiving from a MALS instrument baseline scattering intensity values of a pure buffer, receiving from the MALS instrument scattering intensity values of a sample solution, and characterizing at least one component of the sample solution, resulting in a time series of values of a dimension, D, of the at least one component and a time series of values of excess Rayleigh ratio, R0, of the at least one component, and determining that the values of the dimension, D, fall within a dimension, D, value range and that the values of excess Rayleigh ratio, R0, fall within an excess Rayleigh ratio value range, and transmitting a collect sample solution command to collect the sample solution.

Abstract: Aspects of the disclosure include a system for performing cytometry that can be operated in three operational modes. In one operational mode, a fluorescence image of a sample is obtained by exciting one or more fluorophore(s) with a top-hat-shaped excitation beam with a plurality of beams that are radiofrequency shifted relative to one another. In another operational mode, a sample can be illuminated successively over a time interval by a laser beam at a plurality of excitation frequencies in a scanning fashion to generate an image of the sample from the detected fluorescence. In another operational mode, the system can be operated to illuminate a plurality of locations of a sample concurrently by a single excitation frequency (e.g., a horizontal extent), which is generated, e.g., by shifting the central frequency of a laser beam by a radiofrequency and detected fluorescence is used to analyze the sample.

Abstract: Methods for determining a radius of gyration of a particle in solution using a light scattering detector are provided. The method may include passing the solution through a flowpath in a sample cell, determining respective angular normalization factors for first and second angles of the detector, obtaining a first scattering intensity of the particle in solution at the first angle, obtaining a second scattering intensity of the particle in solution at the second angle, obtaining a 10° scattering intensity of the particle in solution at an angle of about 10°, determining a first particle scattering factor, determining a second particle scattering factor, plotting an angular dissymmetry plot, fitting a line to the angular dissymmetry plot, determining a slope of the line at a selected location on the line, determining the radius of gyration of the particle in solution from the slope of the line, and outputting the radius of gyration.

Abstract: The present invention provides a microfluidic structure for sorting targeted substances. The microfluidic structure includes: an inlet portion having at least one fluid input port; an outlet portion having a plurality of fluid output ports; a first annular flow channel communicated with the inlet portion at the upstream end and rotatably extended; and a second annular flow channel communicated with the downstream end of the first annular flow channel at the upstream end, communicated with the outlet portion at the downstream end and rotatably extended. The first annular flow channel and the second annular flow channel are connected in series according to an S-shaped track, so that the outer side wall of the first annular flow channel is continuously connected to the inner side wall of the second annular flow channel. The cross-sections of the first annular flow channel and the second annular flow channel have a height difference.

Abstract: Implementations disclosed describe a system that includes a deposition chamber, a light source to produce an incident beam of light, wherein the incident beam of light is to illuminate a region of the deposition chamber, and a camera to collect a scattered light originating from the illuminated region of the deposition chamber, wherein the scattered light is to be produced upon interaction of the first incident beam of light with particles inside the illuminated region of the deposition chamber. The described system may optionally have a processing device, coupled to the camera, to generate scattering data for a plurality of locations of the illuminated region, wherein the scattering data for each location comprises intensity of the scattered light originating from this location.

Abstract: A modular optical particle counter sensor and apparatus are described that consolidates counting functionality on a single main counter board and has expandable functionality through connections to plug-in system boards. The modular optical particle sensor may be directly connected to a manifold with an integrated venturi for better controlling the flow rate of the air stream passing through the apparatus for sampling.

Abstract: Aspects of the present disclosure include methods for characterizing particles of a sample in a flow stream. Methods according to certain embodiments include detecting light from a sample having cells in a flow stream, generating an image of an object in the flow stream in an interrogation region and determining whether the object in the flow stream is an aggregate based on the generated image. Systems having a processor with memory operably coupled to the processor having instructions stored thereon, which when executed by the processor, cause the processor to generate an image of an object in a flow stream and to determine whether the object is an aggregate are also described. Integrated circuit devices (e.g., field programmable gate arrays) having programming for practicing the subject methods are also provided.

Abstract: The present disclosure describes a method, a system, and a computer program product of indicating a status of an analytical instrument on a screen of the analytical instrument. In an embodiment, the method, the system, and the computer program product include receiving data from an analytical instrument monitoring a liquid sample, segmenting the received data into data segments for at least two characteristics of at least one of the instrument, the sample, and an operating environment of the instrument, analyzing each of the data segments for the at least two characteristics, retrieving threshold values for the at least two characteristics from a computer data source, calculating at least one status of at least one of the instrument, the sample, and the operating environment, with respect to the analyzed data segments and the threshold values, and displaying the at least one status on a display of the instrument.

Abstract: A particle sorting apparatus includes: a flow cell including a flow channel; an imaging element; and a controller. The controller performs a coarse adjustment onto a position of the flow cell based on an image regarding a flow axis of the flow channel and obtained by the imaging element, while continuously moving the flow cell at a first speed. The controller performs a final adjustment onto the position of the flow cell to allow the first intensity of the first light emitted from the light emitting object flowing in the flow channel to be maximum while moving the flow cell at a second speed that is lower than the first speed.

Abstract: Systems and devices for detecting and characterizing stratified fluid and/or aerosol particles and droplets, and methods of use thereof to, for example, diagnose and prognose respiratory diseases and disorders are provided. The systems typically include optoelectronic sensors for detecting foreign particles like bacteria and pollutants in the air (i.e., the aerosol) based on light scattering. Information collected in this way can be used to, for example, detect or identify respiratory maladies and determine the effectiveness of methods of treatment thereof.

Abstract: Flow cytometers including light collection enhancers are provided. In embodiments, the subject flow cytometers include a flow cell, a light source, an objective lens for focusing particle-modulated light propagating within a first light collection cone and a light collection enhancer configured to collect particle-modulated light propagating along an optical path within a second light collection cone and redirect the collected light such that it is back-propagated along the same optical path and focused by the objective lens for detection. Light collection enhancers of interest include a reflective optical element (e.g., a mirror) and a condenser lens positioned between the reflective optical element and the flow cell. Methods for analyzing a sample are also provided.

Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.

Abstract: A surface profile detection apparatus of a burden in a blast furnace includes a rotating plate mounted immediately above an opening part of the blast furnace and configured to rotate about an opening center of the opening part as a central axis, a rotating means for rotating the rotating plate, and a transmission and reception means for transmitting a detection wave such as a microwave or a millimeter wave in a linear shape along a diametrical direction of the rotating plate and receiving the detection wave. The surface profile detection apparatus performs transmission and reception in a direction orthogonal to a rotating direction of the rotating plate while rotating the rotating plate in synchronization with turning of the shooter so that transmission of the detection wave is not interrupted.

Abstract: Aspects of the present disclosure include a particle sorter with a droplet deflector configured to apply a known offset deflection force to a droplet stream. Particle sorters according to certain embodiments include a flow cell, a light source, e.g., laser, for irradiating an interrogation point of the flow cell, a detector for detecting light from the interrogation point, a droplet generator for producing a droplet stream from fluid exiting the flow cell and a droplet deflector configured to apply a known offset deflection force to the droplet stream. In some cases, the droplet deflector comprises first and second plates configured to be offset from one another. Methods and particle sorting modules for applying a known offset deflection force are also provided.

Abstract: An airborne or liquid particle sensor with a number of advanced features is disclosed. The sensor includes an output channel generating an electrical signal for a particle passing through the sensor, where the electrical signal includes information related to the pulse. The information is processed by the sensor to determine a value that indicates a more accurate particle mass for a sample period than the average mass.

Abstract: A liquid transfer monitoring method to monitor a transfer state of a liquid such as a sample or a reagent having a high transparency which transmits light is provided. The liquid transfer monitoring method comprises a step of transferring a liquid 30 held in a first liquid holding portion 21 to a second liquid holding portion 22 connected to the first liquid holding portion 21, a step of acquiring information 40 relating to a scattered light intensity obtained by irradiating light 91 on the irregular inner surface 23 of at least one of the first liquid holding portion 21 and the second liquid holding portion 22 after starting the transfer of the liquid 30, and a step of monitoring the liquid transfer to the second liquid holding portion 22 based on the information 40 relating to the intensity of scattered light.

Abstract: A scattered light detector comprises a first photodiode array comprising one or more photodiodes arranged in a planar, semicircular pattern on a substrate, each of the one or more photodiodes having an outer edge and an inner edge; and a notch perpendicular to the substrate and located adjacent the inner edge of each of the one or more diodes, and equidistant from the outer edges of each of the one or more photodiodes, the notch configured to accept an optical fiber oriented perpendicular to the plane of the one or more photodiodes. When there are two or more photodiodes, the photodiodes may be divided into two or more segments extending outwardly from the notch. Each of the photodiodes shares a common electrical ground. The planes of the one or more photodiodes of the first and second photodiode arrays are oriented parallel to each other and spaced a predetermined distance apart.

Abstract: A uniformity output device for outputting a uniformity of particles in a slurry, in which an insoluble solid matter is mixed in liquid, includes: a pair of electrodes configured to apply AC voltage to the slurry; a measurement unit configured to measure impedance of the slurry on the basis of the response current flowing through the slurry when AC voltage with changing frequency is applied to the slurry; and a processing unit configured to determine the uniformity by executing a particle equivalent circuit analysis with a parallel circuit formed of a resistor and a capacitor as an element on the basis of the impedance measured by the measurement unit in accordance with the frequency.

Abstract: Disclosed is a method for analysing cells, in which cells are separated and the individual cells pass via a measurement region of a unit for spatially resolved radiation intensity measurement, wherein, for at least one of the separated cells, when passing via the measurement region, a time sequence of spatial intensity patterns of an electromagnetic radiation emitted from and/or influenced by the cell is created, the optical flow of a respective two of the spatial intensity patterns is calculated for at least one portion of the sequence of intensity patterns using a computer unit, and an evaluation of the calculated optical flows occurs. Also disclosed is a device for analysing cells, comprising a device for separating cells, a unit for spatially resolved radiation intensity measurement, and a computer unit for calculating the optical flow of a respective two of the created intensity patterns, and for evaluating the calculated optical flows.

Abstract: The present disclosure provides methods and systems for ghost cytometry (GC), which may be used to produce an image of an object without using a spatially resolving detector. This may be used to perform image-free ultrafast fluorescence “imaging” cytometry, based on, for example, a single pixel detector. Spatial information obtained from the motion of cells relative to a patterned optical structure may be compressively converted into signals that arrive sequentially at a single pixel detector. Combinatorial use of the temporal waveform with the intensity distribution of the random or pseudo-random pattern may permit computational reconstruction of cell morphology. Machine learning methods may be applied directly to the compressed waveforms without image reconstruction to enable efficient image-free morphology-based cytometry.

Abstract: Aspects of the present disclosure include methods for adjusting sensitivity of a photodiode in a light detection system. Methods according to certain embodiments include determining a background data signal from a photodetector at a plurality of detector gains, irradiating the photodetector with a light source at a plurality of different light intensities, generating data signals from the photodetector for the plurality of light intensities at each detector gain and adjusting the photodetector to the detector gain that corresponds to the lowest light irradiation intensity that generates a data signal resolvable from the background data signal. Systems (e.g., particle analyzers) having a light source and a light detection system that includes a photodetector for practicing the subject methods are also described. Non-transitory computer readable storage medium are also provided.

Abstract: For an easy calibration using calibration particles, provided is a measuring device to capture images of target objects. An image analyzer acquires multiple images obtained at a predetermined time interval, (a) specifies the mean-square displacement of a bright point of a calibration particle based on the displacement of the bright point of the calibration particle in the multiple images in a calibration mode, and (b) specifies the mean-square displacement of a bright point of the target particle based on the displacement of the bright point of the target particle in the multiple images in a measurement mode. A particle size analyzer (c) derives the particle size of the target particle from the mean-square displacement of the bright point of the target particle based on the mean-square displacement of the bright point of the calibration particle and the particle size of the calibration particle in an analysis mode.

Abstract: A detection mechanism includes a light source disposed on a substrate, a condensing lens disposed between the substrate and light emitted from the light source, and a photodetector disposed on the substrate and under the condensing lens.

Abstract: In a gas sensing system, a light emitter can emit light through a gas sample toward a concave reflective surface. The reflective surface can redirect the emitted light to propagate through the gas sample toward a light sensor. Using, optionally, the Beer-Lambert Law, the system can determine a concentration of the gas material in the gas sample. By selecting a specified shape for the reflective surface, such as a complete or partial ellipsoid, and locating the light emitter and the light sensor in specified locations, such as at one or both foci of the ellipsoid, the gas sensing system can reduce variation in optical path length, from optical path to optical path, in the light that propagates from the light emitter, to the reflective surface, and to the light sensor. Reducing the variation in optical path length can improve an accuracy in determining the concentration of the gas material.

Abstract: A disposable injection moulded flow cell or cuvette for use in flow cytometer for in vitro assaying of human or animal whole blood and to an investigation method using the flow cytometer. The present disclosure provides a cuvette for use in an optical flow cytometer, comprising a cuboid sheath preparation area, a curved sample injection area with a rectangular cross section, a pyramidal shaped flow formation area, and a sample injector which is arranged in the transition area from the cuboid sheath preparation area to the curved sample injection area.

Abstract: Disclosed are an optical analysis device and an optical analysis method. The present invention provides an optical analysis device for optically analyzing a flow cell, including: a light source configured to emit light to the flow cell; an optical detector including a plurality of detection elements that detects optical signals from reaction regions of the flow cell; and an optical mask including light transmissive mask holes disposed at a front end of each of the detection elements, and an optical analysis method using the same.

Abstract: A substrate cleaning system includes a cleaner module to clean a substrate after polishing of the substrate, a drier module to dry the substrate after cleaning by the cleaner module, a substrate support movable along a first axis from a first position in the drier module to a second position outside the drier module, and an in-line metrology station including a line-scan camera positioned to scan the substrate as the substrate is held by the substrate support and the substrate support is between the first position to the second position. The first axis is substantially parallel to a face of the substrate as held in by the substrate support.

Abstract: There are described herein methods and system for generating an inspection image of an object from radiographic imaging. The method comprises obtaining a plurality of digital images of the object positioned between a radiation source and a photon beam detector, the digital images taken at different object-detector distances or source-detector distances to create unique grain diffraction patterns in each one of the digital images, and forming the inspection image from image features common to the digital images at a common scale and removing the unique grain diffraction patterns.

Abstract: An air data system includes a laser emitter, a laser receiver, and an electronics module. The electronics module includes a processor and computer-readable memory encoded with instructions that, when executed by the processor, cause the laser to emit a coherent light pulse into a target volume locating within an exhaust flow aft of an aircraft. The laser receiver detects backscatter produced by the coherent light pulse interacting with the aft target volume, and the electronics module determines an air data parameter based on the backscatter and at least one of an engine parameter indicative of an engine condition of the aircraft and an aircraft parameter indicative of a state of the aircraft before outputting the air data parameter to a consuming system of the aircraft.

Abstract: A mobile power device capable of detecting gas is disclosed and includes a main body, a gas detection module, a driving and controlling board, a power module and a microprocessor. The main body includes a ventilation opening, a connection port and an accommodation chamber. The ventilation opening is in communication with the accommodation chamber. The gas detection module and the driving and controlling board are disposed within the accommodation chamber. The gas detection module, the power module and the microprocessor are fixed on and electrically connected to the driving and controlling board. The power module is capable of storing an electric energy and outputting the electric energy outwardly. The microprocessor enables the gas detection module to detect and operate. The microprocessor converts the detection information of the gas detection module into a detection data, which is stored and transmitted to the mobile device or an external device.

Abstract: Methods for determining a radius of gyration of a particle in solution using a light scattering detector are provided. The method may include passing the solution through a flowpath in a sample cell, determining respective angular normalization factors for first and second angles of the detector, obtaining a first scattering intensity of the particle in solution at the first angle, obtaining a second scattering intensity of the particle in solution at the second angle, obtaining a 10° scattering intensity of the particle in solution at an angle of about 10°, determining a first particle scattering factor, determining a second particle scattering factor, plotting an angular dissymmetry plot, fitting a line to the angular dissymmetry plot, determining a slope of the line at a selected location on the line, determining the radius of gyration of the particle in solution from the slope of the line, and outputting the radius of gyration.

Abstract: A method is useable for determining a refractive index of an optical medium in a microscope, which has an objective facing toward a sample chamber. The optical medium is one of two optical media, which border two opposing surfaces of a cover slip or object carrier in the sample chamber and form two partially reflective interfaces, which are arranged at different distances from the objective. The method includes: deflecting a measurement light beam by the objective with oblique incidence on the cover slip or object carrier; generating two reflection light beams spatially separated from one another by the measurement light beam being partially reflected at each of the interfaces; receiving the two reflection light beams by the objective and conducting them onto a position-sensitive detector; registering intensities by the position-sensitive detector; and determining the refractive index of the optical medium based on the registered intensities.

Abstract: Light detection systems for simultaneously measuring scattered light (e.g., in a flow stream) from particles having diameters which differ by 100 nm or more are described. Light detection systems according to certain embodiments include a static optical adjustment component, a variable optical adjustment component and a photodetector. Systems and methods for measuring scattered light from a sample (e.g., in a flow stream) and kits having a static optical adjustment component, a variable optical adjustment component and a photodetector are also provided.

Abstract: Systems and methods are described for introducing an impingement gas and an enhancement gas to an aerosolized sample within a spray chamber. A system embodiment includes, but is not limited to, a chamber body; an input port coupled to the chamber body, the input port configured to receive an aerosolized sample and direct the aerosolized sample into the chamber body; an exit port coupled to the chamber body, the exit port configured to receive at least a portion of the aerosolized sample from the chamber body; an impingement gas port coupled to the exit port and configured to introduce an impingement gas to the at least a portion of the aerosolized sample; and an enhancement gas port coupled to the exit port configured to introduce an enhancement gas to the exit port.

Abstract: A system includes a method and apparatus suitable for measuring planar drop sizes in a liquid spray. Measurement may involve illuminating the spray with multiple lasers and measuring the scattered intensities at several view angles using linear arrays. The system may use inverse calculation of the measured scattered intensity to estimate the local drop sizes across the entire plane in a spray. The system includes radiation detectors containing sensing elements, a lens systems, and analog to digital conversion board to convert scattered intensities to drop sizes. In addition, the system may include choppers including at least two unique filters. The filters may be selectively placed in a path between the spray and the sensing elements. By selectively placing a single array may measure both a scattered intensity and an extinction of laser light emitted from the spray.

Abstract: The inventive concept relates to a device for detecting particles in air, said device comprising a receiver for receiving a flow of air comprising particles, a sample carrier, and a particle capturing arrangement. The particle capturing arrangement is configured to separate the particles from the flow of air for and to collect a set of particles on a surface of the sample carrier. The device further comprises a light source configured to illuminate the particles on the sample carrier, such that an interference pattern is formed by interference between light being scattered by the particles and non-scattered light from the light source. The device further comprises an image sensor configured to detect the interference pattern. The device further comprises a cleaner configured for cleaning the surface of the sample carrier for enabling re-use of the surface for collection of a subsequent set of particles.

Abstract: A particle characterization apparatus is disclosed comprising: a first light source; a second light source, a sample cell; a first detector and a second detector. The first light source is operable to illuminate a first region of a sample comprising dispersed particles within the sample cell with a first light beam along a first light beam axis so as to produce scattered light by interactions of the first light beam with the sample. The first detector is configured to detect the scattered light. The second light source is operable to illuminate a second region of the sample with a second light beam along a second light beam axis. The second detector is an imaging detector, configured to image the particles along an imaging axis using the second light beam. The first light beam axis is at an angle of at least 5 degrees to the second light beam axis.