By Particle Light Scattering Patents (Class 356/336)
  • Patent number: 11402326
    Abstract: Systems and methods in which multi-dimensional metric monitoring is used with respect to multi-wavelength scattering for smoke detection are described. A multi-dimensional metric may dynamically track a slope of a relationship between scattered light of multiple wavelengths of scattered light being monitored. A multi-dimensional metric monitoring smoke detection algorithm may utilize multi-dimensional thresholds with respect to monitoring of the multi-dimensional metric for initiating a fire alarm and resetting the fire alarm. An optical measuring chamber utilized for providing multi-wavelength scattering signals utilized in deriving a multi-dimensional metric for smoke detection may be configured for wide-scattering-angle signal collection, such as using a light trapping sub-chamber having a light-guide diaphragm assembly configured for wide-scattering-angle signal collection.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: August 2, 2022
    Assignee: Hong Kong Applied Science and Technology Research Institute Co., Ltd.
    Inventors: Zhinan Yu, Chun Chung Chan, Jiangquan Mai, Fangyi Shi
  • Patent number: 11385164
    Abstract: A method of calibration of a device for analyzing at least one element present in a sample, said device including: a detection assembly configured to acquire an image formed by the interference between a light source and said sample; and digital processing means configured to detect a digital position of at least one element in said sample based on said acquired image; said calibration method including the implementation of a plurality of predetermined displacements of said sample with respect to said detection assembly and, for all of said displacements, the detection of a digital position of a same element to determine the digital position and the real position matching model according to the predetermined displacements and to the digital positions of said element after each displacement.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: July 12, 2022
    Inventors: Alice Douet, Quentin Josso
  • Patent number: 11313780
    Abstract: Methods of analyzing and filtering light scattering data from a sample potentially containing a non-target compound, for example a contaminant. The presence of contaminants result in outliers in the scattering intensity data that increase both symmetry and width of photon counts obtained via analysis. After identification, various outliers are discarded to account for the non-target compounds and thereafter the remaining light scattering data is analyzed. Preferably, analyzing the light scattering data or photon counts involves determining a level to discard an outlier. In particular, the method includes the steps of identifying and quantifying the mode of photon count distribution and using the peak of the mode of distribution to eliminate outliers.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: April 26, 2022
    Inventor: Sandor Balog
  • Patent number: 11237094
    Abstract: A particle-sizing instrument is provided, comprising: a sample cell for receiving a sample comprising a plurality of particles; a light source configured to illuminate the sample with a light beam to produce scattered light by the interaction of the light beam with the particles; a first optical system comprising a first and second optical element respectively configured to split a portion of the scattered light into a first and second portion of scattered light: a second optical system configured to receive the first and second portion of scattered light from the first optical system, and to recombine the first and second portion of scattered light to produce an interference signal at a detection location, and a detector configured to detect the interference signal at the detection location.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: February 1, 2022
    Assignee: Malvern Panalytical Limited
    Inventors: Jason Corbett, Rhys Poolman
  • Patent number: 11221289
    Abstract: An optical detector for particles is provided, including: a channel configured to receive a fluid including at least one particle and to receive at least one incident light ray; a detection system including a plurality of photodetectors, each photodetector being configured to receive light rays coming from the channel and diffused by the at least one particle; and an angular filtering system including a plurality of angular filtering devices each associated with a photodetector of the plurality of photodetectors, each angular filtering device being configured to angularly filter the light rays coming from the channel before reception thereof by the photodetector with which it is associated.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: January 11, 2022
    Inventor: Gabriel Jobert
  • Patent number: 11208568
    Abstract: Subwavelength conducting particles can be arranged on conducting surfaces to provide arbitrary thermal emissivity spectra. For example, a thermal emissivity spectrum can be tailored to suppress a thermal signature of an object without sacrificing radiative cooling efficiency.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: December 28, 2021
    Assignee: Elwha LLC
    Inventors: Gleb M. Akselrod, Erik Edward Josberger, Mark C. Weidman
  • Patent number: 11204310
    Abstract: An optical flow cytometer for blood cell characterization, comprising: a flowcell providing a blood cells flow, at least one light-emitting diode for illuminating blood cells that are flowing in the flowcell, an epifluorescence module in which a same first lens group is used for focusing the—excitation light in the blood cells flow and for collecting fluorescence light coming from each blood cell, and a unitary photodetector for detecting the epifluorescence light coming from the first lens group, at least one of the following measurement modules includes: a light scattering measurement module, an axial light losses measurement module, a particle impedance measurement module.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: December 21, 2021
    Assignee: BIT GROUP FRANCE
    Inventor: Olivier Magnin
  • Patent number: 11193877
    Abstract: A method for characterizing particle objects comprises generating a radiation beam, illuminating with the radiation beam an observation region transited by a particle object, collecting an interference image determined by an interference between a transmitted fraction and a part of the scattered fraction of the radiation beam that propagates around the direction of the optical axis, collecting a part of the scattered fraction that propagates at the scattering angle, and measuring at least one scattered radiation intensity value determined by the part of the scattered fraction, calculating, from the interference image, a pair of independent quantities that define the complex field of the first part of the scattered fraction, calculating, starting from the pair of independent quantities, a theoretical value of scattered radiation intensity, and comparing the measured value with the theoretical scattered radiation intensity value.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: December 7, 2021
    Assignee: EOS S.R.L.
    Inventor: Marco Alberto Carlo Potenza
  • Patent number: 11169069
    Abstract: A particle detecting module is provided. The particle detecting module includes a base, a piezoelectric actuator, a driving circuit board, a laser component, a particulate sensor and an outer cover. A gas-guiding-component loading regain and a laser loading region are separated by the base. By the design of the gas flowing path, the driving circuit board covering the bottom surface of the base, and the outer cover covering the surfaces of the base, an inlet path is defined by the gas inlet groove of the base, and an outlet path is defined by a gas outlet groove of the base. Consequently, the thickness of the particle detecting module is drastically reduced.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: November 9, 2021
    Inventors: Hao-Jan Mou, Ching-Sung Lin, Chin-Chuan Wu, Chih-Kai Chen, Yung-Lung Han, Chi-Feng Huang, Chang-Yen Tsai
  • Patent number: 11156540
    Abstract: A device is disclosed for determining characteristic parameters of the dimensions of nanoparticles in suspension in a liquid. The device emits an incident light beam that is linearly polarized along a polarization axis; a detecting unit comprising a measurement arm that is rotatable with respect to an axis of rotation, the detecting unit comprising first and second detection channels that are separated by a polarization-splitting element arranged in the measurement arm; a fixed sample holder receives a container of cylindrical symmetry of the sample, an axis of symmetry of the container being coincident with the axis of rotation of the measurement arm; and a control unit. The polarization-splitting element of the measurement arm is configured to simultaneously send, over each of the first and second detection channels, respectively, a first and second polarized component of the beam scattered by the sample.
    Type: Grant
    Filed: August 25, 2020
    Date of Patent: October 26, 2021
    Assignees: Cordouan Technologies, Centre National de la Recherche Scientifique, Universite De Bordeaux, Institut Polytechnique De Bordeaux
    Inventors: Florian Aubrit, David Jacob, Olivier Sandre
  • Patent number: 11150175
    Abstract: Methods for determining a radius of gyration of a particle in solution using a light scattering detector are provided. The method may include passing the solution through a flowpath in a sample cell, determining respective angular normalization factors for first and second angles of the detector, obtaining a first scattering intensity of the particle in solution at the first angle, obtaining a second scattering intensity of the particle in solution at the second angle, obtaining a 10° scattering intensity of the particle in solution at an angle of about 10°, determining a first particle scattering factor, determining a second particle scattering factor, plotting an angular dissymmetry plot, fitting a line to the angular dissymmetry plot, determining a slope of the line at a selected location on the line, determining the radius of gyration of the particle in solution from the slope of the line, and outputting the radius of gyration.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: October 19, 2021
    Assignee: M & J Scientific, LLC
    Inventors: Max Haney, Michael P. Murphy
  • Patent number: 11119021
    Abstract: The invention describes a laser sensor module (100) for detecting ultra-fine particles (10) with a particle size of 300 nm or less, more preferably 200 nm or less, most preferably 100 nm or less, the laser sensor module (100) comprising: —at least one laser (110) being adapted to emit laser light to at least one focus region in reaction to signals provided by at least one electrical driver (130), —at least one detector (120) being adapted to determine a self-mixing interference signal of an optical wave within a laser cavity of the at least one laser (110), wherein the self-mixing interference signal is caused by reflected laser light reentering the laser cavity, the reflected laser light being reflected by a particle receiving at least a part of the laser light, —the laser sensor module (100) being arranged to perform at least one self-mixing interference measurement, —the laser sensor module (100) being adapted to determine a first particle size distribution function with a first sensitivity by means of at
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: September 14, 2021
    Inventors: Johannes Hendrikus Maria Spruit, Alexander Marc Van Der Lee, Petrus Theodorus Jutte, Cornelis Reinder Ronda, Pascal De Graaf, Holger Moench, Joachim Wilhelm Hellmig
  • Patent number: 11092534
    Abstract: A method for detecting the concentration of particles in a fluid is disclosed. The method comprises the steps of: S1: introducing a pure fluid into a detection device to obtain a scatter background noise value U noise output by the detection device; S2: introducing a fluid to be detected into the detection device, obtaining scatter signals output by the detection device, and obtaining voltage signals of standard particles; S3: sampling signals of the fluid in a certain period of time, extracting effective signals, carrying out threshold value analysis on the effective signals Ux obtained by sampling, and obtaining the number of particles present in the period of time; and S4: obtaining the concentration of the particles in the fluid according to the number of particles in S3. According to this method, the accuracy in calculation of the concentration of particles in a fluid can be effectively improved.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: August 17, 2021
    Inventors: Yongzhong Nie, Zhongping Zhang
  • Patent number: 11073462
    Abstract: To reduce the complexity and risk associated with activated platelet transfusions, thrombocytopenic patients are transfused with exclusively non-activated platelets. A preferred embodiment is through routine screening of platelet units in the hospital blood bank using dynamic light scattering and selective allocation of platelets, with non-activated platelets being exclusively transfused to thrombocytopenic patients, especially patients with cancers such as hematologic malignancies. Activated platelets typically contain activated factors of the innate immune system called complement, transforming growth factor beta (TGF?), interleukin 6 (IL-6), CD40 ligand (CD40L) and C-reactive protein (CRP) for example. Some of these activated factors have already been shown to correlate with microparticles and others are expected to correlate: the higher the platelet activation the more microparticles and the higher the concentration of these factors.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: July 27, 2021
    Assignee: LightIntegra Technology Inc.
    Inventors: Elisabeth Maurer, Daniel Millar
  • Patent number: 11045668
    Abstract: A volumetric radiation dose detector provides radiation sensors distributed along a closed surface presenting surface normals that vary over a range of azimuth and altitude angles to provide accurate dose modeling for radiation received at a comparable range of angles. Concentric layers of surfaces provide volumetric dose information that can be used to directly produce useful dose maps and assessments.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: June 29, 2021
    Assignee: HRS International Solutions, LLC
    Inventors: Dante E. Roa, Jimmy Hernandez Bello, Jose Vidal Valladolid Salazar, Roger Challco Chalco, Carmen Sandra Guzman Calcina, Modesto Edilberto Montoya Zavaleta, Andres Miguel Gonzales Galvez
  • Patent number: 11020058
    Abstract: A system for calculating blood pressure may include a sensor system and a control system. The control system may be capable of controlling one or more sensors of the sensor system to take at least two measurements, the at least two measurements including at least one measurement taken at each of two or more different measurement elevations of a subject's limb. In some examples, the control system may be capable of determining a blood flow difference based on the at least two measurements, of determining a hydrostatic pressure difference based on the two or more different elevations of the at least two measurements and of estimating a blood pressure based on one or more values of blood flow, the hydrostatic pressure difference and the blood flow difference.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: June 1, 2021
    Assignee: QUALCOMM Incorporated
    Inventors: Lars Lading, David Boettcher Baek
  • Patent number: 11009445
    Abstract: An in-fluid floating substance measurement flow cell includes: a main body having at least a predetermined portion made of a material having translucency; and a flow passage formed inside the main body, having both end openings at an outer surface of the main body in a substantially identical direction, and configured such that fluid flows in the flow passage. The flow passage has a predetermined section arranged between two opposing flat wall surfaces facing each other, and the predetermined portion includes the predetermined section.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: May 18, 2021
    Assignee: RION Co., Ltd.
    Inventors: Tomonobu Matsuda, Takashi Minakami, Daisuke Sakaue, Daisuke Shinozaki
  • Patent number: 10948625
    Abstract: A system, method, and device for determining volume concentration with diffraction of electromagnetic radiation. A device for determining a volume concentration of a fluid in a sample comprises a transducer, a transmitter, a detector, and a processor. The transducer generates a standing acoustic wave through the sample. The transmitter emits electromagnetic (EM) radiation into the sample such that the EM radiation is diffracted by the sample. The detector is responsive to the diffracted EM radiation and generates a signal indicative of a wavelength of an acoustic wave corresponding to the standing acoustic wave. The processor analyzes the signal to determine the volume concentration of the fluid in the sample.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: March 16, 2021
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Satyan Gopal Bhongale, Wolfgang Hartmut Nitsche, John Laureto Maida, Michel Joseph LeBlanc
  • Patent number: 10895532
    Abstract: An airborne microorganism measurement device includes a housing including a first body and a second body, an air passage formed between the first body and the second body such that air containing airborne microorganisms pass therethrough, a charging part and a collecting part disposed in the air passage to charge and collect the airborne microorganisms, a high voltage generating device provided in the first body to supply a high voltage to the charging part and the collecting part, and a light emitting unit and a light receiving part provided in the second body to detect a fluorescent signal generated by irradiating the airborne microorganisms collected in the collecting unit with light.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: January 19, 2021
    Inventors: Sujin Lee, Bongjo Sung, Ilna Son, Sanggu Lee
  • Patent number: 10895500
    Abstract: An optical measurement method and system. The system includes, and method applies, a light source, a beamsplitter, at least one filter, a output photodetector for acquiring data of a sample, and a correction photodetector for correcting and maintaining output intensity from the light source. The filter is located between the light source and the correction photodetector for normalizing the spectrum of the input light being applied to input light correction. The filter may be incorporated into the beamsplitter and may be tuned to filter light from the light source for providing non-zero transmission of light with a near-zero gradient for wavelengths in a portion of the spectrum of the input light being applied to the sample and read by the output photodetector. The filter may also or alternatively be located downstream of the beamsplitter to correct for wavelength sensitivity of the correction photodetector.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: January 19, 2021
    Inventors: Elmar Prenner, Kirat Singh
  • Patent number: 10876948
    Abstract: A particle sensing device according to one embodiment comprises: a light-emitting unit for emitting light; a first flow path unit arranged under the light-emitting unit so as to be vertical to an optical shaft of the light-emitting unit, and through which air including particles flows; a light-receiving unit arranged at the optical shaft under the first flow path unit, and on which light that has passed through the first flow path is incident; and a light-absorbing unit arranged at the optical shaft under the light-receiving unit and absorbing light that has passed through the light-receiving unit.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: December 29, 2020
    Assignee: LG INNOTEK CO., LTD.
    Inventors: Jae Hyun Kim, Ji Hoon Kim
  • Patent number: 10866180
    Abstract: A particle diameter acquisition device includes an intensity distribution acquisition unit configured to acquire an intensity distribution of scattered light scattered from a multi-phase flow including dispersed phase at the time of irradiating the multi-phase flow with irradiation light, an attenuation gradient acquisition unit configured to acquire an attenuation gradient in the intensity distribution on the basis of the intensity distribution of the scattered light, a concentration acquisition unit configured to acquire a concentration of the dispersed phase in the multi-phase flow, a database configured to store intensity distribution data which is an intensity distribution of scattered light for each particle diameter and concentration of a dispersed phase, and a particle diameter acquisition unit configured to acquire a particle diameter of the dispersed phase on the basis of the acquired attenuation gradient, concentration, and intensity distribution data with reference to the intensity distribution da
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: December 15, 2020
    Inventors: Yoshiyuki Kondo, Yoshiteru Komuro, Atsushi Kodama, Koichi Tanimoto
  • Patent number: 10852187
    Abstract: The disclosure provides a Raman spectrum detection apparatus, including: a laser configured to emit laser light to an object to be detected; a Raman spectrometer configured to receive Raman light from the object; an imaging device configured to obtain an image of the object; and a controller configured to control an operation of the detection apparatus based on grayscales of the image. There is further provided a Raman spectrum detection method.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: December 1, 2020
    Assignee: Nuctech Company Limited
    Inventors: Haihui Liu, Hongqiu Wang, Jianhong Zhang, Jiaqian Zuo
  • Patent number: 10845287
    Abstract: Disclosed herein is a method of characterizing particles in a sample. The method comprises illuminating the sample in a sample cell with a light beam, so as to produce scattered light by the interaction of the light beam with the sample; obtaining a time series of measurements of the scattered light from a single detector; determining, from the time series of measurements from the single detector, which measurements were taken at times when a large particle was contributing to the scattered light; determining a particle size distribution, including correcting for light scattered by the large particle.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: November 24, 2020
    Assignee: Malvern Panalytical Limited
    Inventors: Jason Corbett, Alex Malm
  • Patent number: 10843526
    Abstract: An air-conditioning system of a motor vehicle may include a channel system configured to allow air to flow therethrough during operation and at least one heat exchanger positioned within the main channel and configured to air-condition air supplied to a motor vehicle interior of the motor vehicle. The channel system may include a main channel. The system may include a sensor device configured to measure an air characteristic of air to be analysed. The sensor device may include an analysis channel which the air to be analysed can flow through, a generation device configured to generate electromagnetic waves penetrating the analysis channel, a sensor temperature-control space separated from the analysis channel, and a temperature-control channel configured to apply air-conditioned air to the generation device to control a temperature of the generation device. The generation device is at least partially arranged in the sensor temperature-control space.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: November 24, 2020
    Assignee: Mahle International GmbH
    Inventors: Rainer Knoeller, Markus Michael, Anja Reiter, Walter Wolf
  • Patent number: 10837889
    Abstract: Apparatus (200) for measuring the particle-size distribution of a sample by light-scattering comprises a focusing optic (202) for producing a converging beam (203) generally along a propagation axis z. The apparatus comprises a mounting system which allows a dry sample cell (208A) and a wet sample cell (208B) to be mounted in the converging beam at different times and in respective planes which are mutually inclined so that in use of the apparatus respective positions (212, 214) at which transmitted light is focused for the two cells have a difference in displacement from the z axis that is less than for the case where the respective planes are substantially parallel. This allows use of a cheaper and less complex translation stage within the apparatus for mounting an optical detector for locating the two focus positions.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: November 17, 2020
    Assignee: Malvern Panalytical Limited
    Inventor: David Michael Spriggs
  • Patent number: 10835313
    Abstract: Systems and methods for performing RF ablation while monitoring the procedure using low coherence interferometry (LCI) data are described. A catheter includes a distal section, a proximal section, a multiplexer, and a sheath coupled between the distal section and the proximal section. The distal section includes one or more electrodes configured to apply RF energy to a portion of a sample in contact with the electrode. The distal section also includes a plurality of optical elements configured to transmit one or more beams of exposure radiation away from the distal section of the catheter. The proximal section includes an optical source configured to generate a source beam of radiation and a detector configured to generate depth-resolved optical data. The multiplexer is configured to generate the one or more beams of exposure radiation from the source beam of radiation.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: November 17, 2020
    Assignee: MEDLUMICS S.L.
    Inventors: Eduardo Margallo Balbás, José Luis Rubio Guivernau, Santiago Jiménez Valero, Alejandro Barriga Rivera, Justo Contreras Bermejo, Juan Lloret Soler
  • Patent number: 10795062
    Abstract: A system and method are provided for forming one-way light transmissive layers implementing optical light scattering techniques in those layers, and to objects, object portions, lenses, filters, screens and the like that are formed of, or that otherwise incorporate, such one-way light transmissive layers. Processes are provided by which to form, or otherwise incorporate, one or more one-way light transmissive, or substantially transparent, object portions or layers in solid or hollow objects Individual one-way light transmissive layers are formed of substantially-transparent sub-micrometer spheres, including micro-particles and/or nano-particles, with nano-voids incorporated between them.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: October 6, 2020
    Assignee: Face International Corporation
    Inventors: Clark D Boyd, Bradbury R Face, Jeffrey D Shepard
  • Patent number: 10764518
    Abstract: The present invention pertains to a pixel for use in a system for determining a distance to an object by range gating, said pixel comprising: a first charge storage well (221) and a second charge storage well (222) for accumulating electrical charges representative of amounts of light impinging on said pixel during respective sets of exposure intervals, wherein said first charge storage well (221) has a charge capacity that is at least 50% greater than a charge capacity of said second charge storage well (222). The invention also pertains to a range gating system comprising such a pixel.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: September 1, 2020
    Assignee: XENOMATIX NV
    Inventors: Dirk Van Dyck, Rik Paesen
  • Patent number: 10761008
    Abstract: A particle detecting device includes a chamber 30; a first introduction flow path 225 for introducing a particle-containing fluid into the chamber 30; a second introduction flow path 235 for introducing a particle-free fluid into the chamber 30; a light source 10 configured to illuminate fluid in the chamber 30 to detect particles contained in the fluid; a discharge flow path 260 for discharging fluid from the chamber 30; an introduction flow meter 245 configured to measure a flow rate of fluid flowing through the second introduction flow path 235; and a control unit 301 configured to perform control such that a fluid having a total flow rate obtained by adding a predetermined flow rate of fluid flowing through the first introduction flow path 225 to a flow rate of fluid flowing through the second introduction flow path 235, the flow rate being measured by the introduction flow meter 245, flows through the discharge flow path 260.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: September 1, 2020
    Inventor: Seiichiro Kinugasa
  • Patent number: 10753843
    Abstract: Provided is a gel particle measuring apparatus for detecting scattered light generated by light irradiation at a production start time point of a gel particle, and performing measurement promptly and accurately while suppressing attenuation of the scattered light in a solvent in which the phenomenon occurs.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: August 25, 2020
    Assignee: PROJECT KBF CO., LTD.
    Inventors: Toru Obata, Juichiro Ukon
  • Patent number: 10690694
    Abstract: A device (10) for determining a parameter of a fluid flow includes an elastically deformable boom (23, 28, 33, 42, 47), with an inflow area (29, 31, 32, 37, 38, 39, 40, 44, 45, 46, 49, 50) for fluid and a measurement apparatus (16) measuring deformation of the boom. A section of the inflow area is aligned askew and/or curved to a main fluid inflow direction (25). The boom has an inflow structure (24, 30, 34, 43, 48) on one free end. The inflow structure has the fluid inflow area. To determine the parameter of the fluid flow at high resolution, in particular a high angle resolution, the boom has a reflection surface (27) on a side facing away from the inflow structure and the measurement apparatus (16) has a laser (17). A beam axis (26) of the laser (17) is directed to the reflection surface (27) of the boom.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: June 23, 2020
    Inventors: Joachim Peinke, Michael Hölling, Stephan Barth, Jaroslaw Puczylowski
  • Patent number: 10598603
    Abstract: Provided is an inspection lighting device with which, even when changes in light that occur at respective feature points on an object to be inspected are small, the amounts of those changes in light can be determined across the entire field-of-view range, and the feature points can be detected under exactly the same conditions. An inspection lighting device 100 includes a surface light source 1 and a lens 2 that is disposed between the surface light source 1 and an inspection object W, the lens 2 being disposed nearer to the inspection object W such that at least one of a shielding mask M1 and a filtering means F1 is located centered around a focal distance position of the lens. An irradiation solid angle of light emitted from the surface light source 1 and irradiated onto the inspection object W by the lens 2 is configured to have solid angle regions as desired, the solid angle regions having specific optical attributes.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: March 24, 2020
    Inventor: Shigeki Masumura
  • Patent number: 10571386
    Abstract: Light from a light source is directed at a flow path of particles of a flow cytometer. The directed light results in a light pattern having a plurality of lobes. A first signal is detected exceeding a first threshold. A second signal exceeding a second threshold is detected, wherein the second threshold is greater than the first threshold. Based on detecting the second trigger after detecting the first trigger, is determined that the first and second signals were created by a relatively large particle.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: February 25, 2020
    Assignee: Stratedigm, Inc.
    Inventors: Shervin Javadi, Arjuna Ragunath Karunaratne
  • Patent number: 10559072
    Abstract: An image detection device executing a detection process for images of a subject obtained by illuminating cyclically the subject with light having different spectral properties and capturing the subject at timings synchronizing with illuminating cycles of the light, the image detection device comprising a shift vector detection means that detects a shift vector of the subject based on a comparison result between an image of the subject captured at a current cycle and an image of the subject which is captured at a past cycle and is illuminated with the light having a same spectral property as that of the light illuminated at the current cycle.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: February 11, 2020
    Inventor: Takao Makino
  • Patent number: 10539490
    Abstract: An apparatus of ultrafast particle dynamics measurement based on photon ensemble correlation spectroscopy include steps of: dispersing a particle sample to be detected; establishing a plurality of sampling volumes, and collecting dynamic scattered light signals in parallel; and constructing sample ensembles based on scattered signals of the sampling volumes, analyzing time correlations between the sample ensembles, and detecting particle dynamic characteristics. A period for a single measurement of particles according to the method can be in the range of several milliseconds to several tens of milliseconds, which is conducive to real-time detection. More accurate and reliable correlation characterization can be obtained by combining the detected complex-valued scattered signals with both amplitude and phase information. Furthermore, the particle detection is able to be spatially resolved, so as to achieve spatially resolved particle dynamic characteristics.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: January 21, 2020
    Inventors: Peng Li, Pei Li
  • Patent number: 10539496
    Abstract: Devices for detecting particle sizes and distributions using focused light scattering techniques, by passing a sample through a focused beam of light, are disclosed. In one embodiment, the devices include one or more lasers, whose light is focused into a narrow beam and into a flow cell, and dispersions are passed through the flow cell using hydrodynamic sample injection. In another embodiment, a plurality of lasers is used, optionally with hydrodynamic sample injection. Particles pass through and scatter the light. The scattered light is then detected using scatter and extinction detectors, and, optionally, fluorescence detectors, and the number and size of the particles is determined. Particles in the size range of 0.1 to 10 ?m can be measured. Using the device, significantly smaller particles can be detected than if techniques such as EQELS, flow cytometry, and other conventional devices for measuring biological particles.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: January 21, 2020
    Assignee: Invitrox, Inc.
    Inventor: Don Gabriel
  • Patent number: 10527543
    Abstract: The technology disclosed in this application provide for non-destructive and non-contact optical characterization of fiber reinforced plastic composites and other structures under test based on optical transmission scanning.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: January 7, 2020
    Assignee: General Photonics Corporation
    Inventors: Anton Khomenko, Xiaotian Steve Yao, Oleksii Karpenko, Xiaojun James Chen
  • Patent number: 10520412
    Abstract: Disclosed herein is a method of characterizing particles in a sample. The method comprises illuminating the sample in a sample cell with a light beam, so as to produce scattered light by the interaction of the light beam with the sample; obtaining a time series of measurements of the scattered light from a single detector; determining, from the time series of measurements from the single detector, which measurements were taken at times when a large particle was contributing to the scattered light; determining a particle size distribution, including correcting for light scattered by the large particle.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: December 31, 2019
    Assignee: Malvern Panalytical Limited
    Inventors: Jason Corbett, Alex Malm
  • Patent number: 10495562
    Abstract: In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: December 3, 2019
    Assignee: Beckman Coulter, Inc.
    Inventors: George C. Malachowski, Paul Barclay Purcell, Edward Allan Stanton, Kenneth Michael Evans
  • Patent number: 10488313
    Abstract: A particle mass concentration in an aerosol volume can be detected by an optical particle sensor. In order to ensure that different degrees of contamination of the optical particle sensor can be detected by the sensor and can be taken into consideration, the optical particle sensor identifies individual particles at low particle concentrations of up to 1000 particle s/cm3.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: November 26, 2019
    Assignee: PARAGON AG
    Inventor: Ralf Moenkemoeller
  • Patent number: 10481004
    Abstract: A light wavelength measurement method of measuring a wavelength of target light includes: receiving target light on a second dispersion device that disperses the target light into a plurality of second beams which reach a plurality of positions corresponding to the wavelength of the target light; and measuring the wavelength of the target light, by using the plurality of the second beams as a vernier scale for measuring the wavelength of the target light within a wavelength range specified by a main scale.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: November 19, 2019
    Inventors: Tsuyoshi Konishi, Takema Satoh, Tomotaka Nagashima
  • Patent number: 10458896
    Abstract: The present invention relates to methods and systems for image cytometry analysis, typically at low optical magnification, where analysis is based on detection of biological particles using UV bright field, dark field or one or more sources of excitation light. The system comprises illumination means (11, 112), a sample holder (100), a sample compartment (101), imaging means (120), collection means (121), light modulation means (122, 123), and detection means (130) with active detection elements (131).
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: October 29, 2019
    Assignee: ChemoMetec A/S
    Inventors: Martin Glensbjerg, Johan Holm, Søren Kjaerulff, Frans Ejner Ravn Hansen
  • Patent number: 10379114
    Abstract: A method for determining a radius of elements suspended in a medium includes binding the elements to nanoparticles to form bound element-nanoparticle aggregates, superposing first and second Doppler-shifted optical waves having a variable frequency shift between them in the medium such that there is a gain in energy of the first optical wave with respect to the second optical wave, varying the frequency shift and measuring the gain while varying the frequency shift to determine the value of the frequency shift at which there is a peak in the gain, determining the radius of the bound element-nanoparticle aggregates based on the value of the frequency shift at which there is a peak in the gain, and determining the radius of the elements based on the radius of the bound element-nanoparticle aggregates.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: August 13, 2019
    Assignee: Solaris Nanosciences, Inc.
    Inventor: Nabil Lawandy
  • Patent number: 10368775
    Abstract: Systems and methods for evaluating neuromodulation via hemodynamic responses are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a neuromodulation catheter comprising an elongated shaft having a distal portion, and a plurality of electrodes spaced along a distal portion. The system can further include a controller communicatively coupled to the electrodes. The controller can be configured to apply first and second stimuli at and/or proximate to a target site within a blood vessel before and after delivering neuromodulation energy to the target site, and detect, via at least one of the electrodes, vessel impedance resulting from the first and second stimuli to determine a baseline impedance and a post-neuromodulation impedance. The controller can further be configured to assess the efficacy of the neuromodulation based, at least in part, on a comparison of the baseline impedance and the post-neuromodulation impedance.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: August 6, 2019
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Douglas A. Hettrick, Avram Scheiner
  • Patent number: 10369776
    Abstract: An additive manufacturing system that retains a print head for printing a three-dimensional part in a layer-by-layer manner using an additive manufacturing technique, where the retained print head is configured to receive a consumable material, melt the consumable material, and extrude the molten material. The system also includes a velocimetry assembly configured to determine flow rates of the molten material, and a controller assembly configured to manage the extrusion of the molten material from the print head, and to receive signals from the velocimetry assembly relating to the determined flow rates.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: August 6, 2019
    Assignee: STRATASYS, INC.
    Inventor: J. Samuel Batchelder
  • Patent number: 10365197
    Abstract: An optical particle sensor has at least first and second threshold settings applied to an optical sensor or a sensor signal to obtain first and second optical sensor readings. The first and second optical sensor readings are processed to determine a parameter which is dependent on a type of pollution event. The parameter is used to determine from at least one of the first and second optical sensor readings a mass of all particles below a first particle size. In this way the mass of all particles below a desired size can be evaluated, even though the optical sensor may not be responsive to the smallest particles.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: July 30, 2019
    Inventors: Michiel Johannes Jongerius, Gerben Kooijman, Koray Karakaya, Okke Ouweltjes
  • Patent number: 10359350
    Abstract: Disclosed herein is a novel optical particle characterization system and method of use that can be applied to harsh environments. By separating the sensing components from the electronics unit and using optical fibers for interconnection, only the sensing components need to endure harsh environmental conditions. This reduces the design constraints on the electronics unit and permits the incorporation of optical components into the sensing probe that can withstand high-temperature and high-pressure environments.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: July 23, 2019
    Inventors: Hai Lin, Gregor Arthur Waldherr
  • Patent number: 10267722
    Abstract: A flow cytometry system including a measuring chamber, an injection device arranged to inject a flow of biological particles to be analyzed in the measuring chamber, an evacuation device arranged to evacuate outside of the cytometry system the flow of biological particles injected in the measuring chamber, a measuring set arranged to measure at least one optical property of the biological particles to be analyzed, the measuring set including an emission device arranged to emit a light beam in the direction of the measuring chamber and capable of crossing the flow of biological particles, and at least one collecting device arranged to collect light rays coming from the measuring chamber, where the flow cytometry system further includes a support on which the injection device, the evacuation device, the emission device and the at least one collecting device are mounted.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: April 23, 2019
    Assignee: ARTEION
    Inventor: Alain Rousseau
  • Patent number: 10264237
    Abstract: As to N images captured at different focus positions, which are arrayed in order of focus positions, N/2 images are set as feature point extraction images so that at least one of two adjacent images becomes a feature point extraction image; corresponding points corresponding to a feature point, extracted from the feature point extraction image, are searched for from the other images; a correction parameter, with which corresponding positions of the N images are matched, is calculated from a positional relation of the feature point and the corresponding points; and, with an image whose view angle is the smallest among the N images as a reference, the other images are corrected.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: April 16, 2019
    Inventors: Keisuke Omori, Kei Tokui