At Right Angles To The Light Beam (e.g., Nephelometer) Patents (Class 356/339)
  • Patent number: 10934182
    Abstract: A system and method for treating flowing water systems with a plasma discharge to remove or control growth of microbiological species. The system and method protect other components of the water system from being damaged by excess energy from the electrohydraulic treatment. The system and method also recycle ozone gas generated by a high voltage generator that powers the plasma discharge to further treat the water. A gas infusion system upstream of or inside a plasma reaction chamber may be used to create fine bubbles of ozone, air, or other gases in the water being treated to aid in plasma generation.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: March 2, 2021
    Assignee: NCH Corporation
    Inventors: Adrian J. Denvir, David F. Vela, Matt C. Holloway
  • Patent number: 10908061
    Abstract: A tomography duct for wind tunnels includes a plurality of light sources and sensors displaced around a support structure. The light sources are cycled and sensor measurements are made from sensors opposite the light sources. Tomographic algorithms are used to determine an extinction map from the sensor measurements. The extinction map provides details about particles in a cross-section of the air flow through the tomography duct.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: February 2, 2021
    Assignee: PLEXAR ASSOCIATES, INC.
    Inventors: Timothy J. Bencic, David P. Rohler, Amy F. Fagan, Steven H. Izen, Arjun K. Maniyedath
  • Patent number: 10823672
    Abstract: Various turbidimeters are described that can detect light directly in a substantially circular, e.g., encompassing, manner such that an increased amount of scattered light from a sample vial may be detected by a light detector, e.g., a photodiode or photodiode array. In an embodiment, a substantially circular photodiode array is provided to directly detect scattered light in an arc about the sample vial. In other embodiments, light guides are provided in an arc element that guides light to a detector or detectors. Other aspects are described and claimed.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: November 3, 2020
    Assignee: HACH COMPANY
    Inventors: Richard Edward Leggett, Wayne Boris Perdue, Andreas Mitreiter
  • Patent number: 10768106
    Abstract: A method of monitoring a solid component of a reactor feed stream in a polymer production system, comprising (a) measuring a turbidity of the reactor feed stream, wherein the reactor feed stream comprises a solid component of a polymerization catalyst system, and (b) translating the turbidity of the reactor feed stream into a concentration of the solid component in the reactor feed stream. A method of monitoring a solid component of a reactor feed stream in a polymer production system, comprising (a) measuring a turbidity of a precontactor feed stream, wherein the precontactor feed stream comprises a solid component of a polymerization catalyst system, and (b) translating the turbidity of the precontactor feed stream into a concentration of the solid component in a precontactor effluent stream, wherein the precontactor effluent stream comprises the reactor feed stream.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: September 8, 2020
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Eric D. Schwerdtfeger, Daniel G. Hert, Max P. McDaniel
  • Patent number: 10663398
    Abstract: A system for determining the characteristics of a gas is described, comprising at least one beam of coherent and monochromatic light, detecting means of scattered light comprising at least one photo-detector, at least one measuring chamber within which the beam and the detecting means are operating, and control means operatively connected to the photo-detector for recording an amount of scattered light according to the Rayleigh scattering principle depending on the physical characteristics of the gas molecule and on a wavelength of the coherent and monochromatic light, the beam of coherent and monochromatic light being emitted by at least one laser with continuous wave. A method for measuring the characteristics of a gas through such system is further described.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: May 26, 2020
    Assignee: INRIM
    Inventor: Marco Pisani
  • Patent number: 10571258
    Abstract: The present application proposes an improved position sensor, a conveying device comprising the same and a method for position correction by using the same. The position sensor includes at least two light emitters, a light receiver array and a pedestal, the pedestal having a central plane and at least two sloping surfaces tilting towards a center of the pedestal at opposite edges, the at least two light emitters being arranged on the at least two sloping surfaces respectively, and the light receiver array being arranged on the central plane of the pedestal.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: February 25, 2020
    Assignees: BOE TECHNOLOGY GROUP CO., LTD., BEIJING BOE DISPLAY TECHNOLOGY GROUP CO., LTD.
    Inventors: Pengyu Qi, Dong Wang, Jian Hou
  • Patent number: 10520433
    Abstract: Various turbidimeters are described that can detect light directly in a substantially circular, e.g., encompassing, manner such that an increased amount of scattered light from a sample vial may be detected by a light detector, e.g., a photodiode or photodiode array. In an embodiment, a substantially circular photodiode array is provided to directly detect scattered light in an arc about the sample vial. In other embodiments, light guides are provided in an arc element that guides light to a detector or detectors. Other aspects are described and claimed.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: December 31, 2019
    Assignee: HACH COMPANY
    Inventors: Richard Edward Leggett, Wayne Boris Perdue, Andreas Mitreiter
  • Patent number: 10490053
    Abstract: Detection and real-time reporting (via wireless to a remote receiver) of the release of harmful or otherwise unwanted chemicals or chemicals of corrosion into the environment and, more particularly, the undesired release of such chemicals from pipelines, supporting energy/electric/heating/cooling/storage/distribution infrastructure, refineries, chemical plants, factories, processing and manufacturing plants and equipment, storage tanks, engines, containers and the like. One or more detection devices can be placed nearby potential areas where leaks occur, or anywhere monitoring for leaks is desired. In some embodiments, the detection devices are integrated into components for monitoring said component for unwanted emissions.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: November 26, 2019
    Inventors: Gregory J. Hummer, Matthew Hummer
  • Patent number: 10481064
    Abstract: A ballast water monitoring device and a method for detecting live phytoplankton are disclosed. The device comprises a chamber for receiving a sample, at least one light source to emit light towards the sample, a light detector to receive light from the sample and generate a light signal, and a controller. The controller is configured to control the at least one light source to emit a single pulse of light, calculate the variable fluorescence [Fv] of the sample in response to the pulse of light, at time intervals less than the duration of the pulse of light, compare the calculated variable fluorescence to a predetermined reference limit, and perform an action if the calculated variable fluorescence is greater than the predetermined reference limit.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: November 19, 2019
    Assignee: CHELSEA TECHNOLOGIES GROUP LTD
    Inventors: Kevin Oxborough, John Attridge, David Andrewes
  • Patent number: 10458897
    Abstract: The invention concerns a method for identifying biological particles from a stack of holographic images obtained by means of an optical system. A stack of image blocks centered on the biological particle to be analysed is extracted from the stack of images and a reference block corresponding to the focus plan is determined. A characteristic magnitude is calculated for each block of the stack and the profile of this characteristic magnitude along the optical axis of the system is compared with a plurality of standard profiles relative to known types of particle. Alternatively, blocks of the stack are extracted from the stack of blocks for predetermined defocusing deviations and the extracted blocks are compared with standard blocks relative to known types of particle.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: October 29, 2019
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, BIOMERIEUX
    Inventors: Francois Perraut, Pierre Joly, Quentin Josso, Meike Kloster-Landsberg, Alice Douet
  • Patent number: 10456767
    Abstract: A cytometric mechanism includes: a flow path through which a cell suspension is made to flow; a liquid drive unit for sending the cell suspension which is in the flow path; and a computation unit for irradiating, with irradiation light from a light source, a cell suspension flowing through a flow cell, and for finding a cell survival rate in the cell suspension on the basis of a resulting forward scattered light intensity and transmittance and/or side scattered light intensity. The invention is provided with a calibration curve database for storing, in advance, respective calibration curves indicative of a relationship between viable cell concentration and forward scattered light intensity, a relationship between dead cell concentration and the transmittance, and a relationship between a cell survival rate and the side scattered light intensity.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: October 29, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Masako Kawarai, Toshinari Sakurai, Akihiro Shimase, Hiroyuki Koshi
  • Patent number: 10317285
    Abstract: A system for testing optical resolution of an optical device includes an optical resolution target assembly including a target that is heated. The target emits a first light beam at a first wavelength in response to being heated. The first light beam has first and second components that are discernible from one another when the target is heated. The system may also include an illuminator that emits light at a second wavelength that differs from the first wavelength onto the target. The target emits a second light beam having third and fourth components that are discernible from one another when the illuminator emits light at the second wavelength onto the target.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: June 11, 2019
    Assignee: The Boeing Company
    Inventor: Christopher D. Koresko
  • Patent number: 10302553
    Abstract: A gas exhaust by-product measurement system is provided. A gas chamber is configured to receive exhaust from the exhaust output. A light source, light detector, and at least one optical element are positioned so that a light beam from the light source is directed to the at least one optical element a plurality of times before reaching the light detector. At least one heater provides heat to the at least one optical element. A plurality of purge gas nozzles are in fluid connection with the optical cavity. A high flow line is in fluid connection between a purge gas source and the plurality of purge gas nozzles. A low flow line is in fluid connection between the purge gas source and the plurality of purge gas nozzles. At least one flow controller manages a plurality of flow rates including a high flow and a low flow.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: May 28, 2019
    Assignee: Lam Research Corporation
    Inventors: Cristian Siladie, Luc Albarede, Yassine Kabouzi, Edward J. McInerney, Sassan Roham
  • Patent number: 10281393
    Abstract: Various turbidimeters are described that can detect light directly in a substantially circular, e.g., encompassing, manner such that an increased amount of scattered light from a sample vial may be detected by a light detector, e.g., a photodiode or photodiode array. In an embodiment, a substantially circular photodiode array is provided to directly detect scattered light in an arc about the sample vial. In other embodiments, light guides are provided in an arc element that guides light to a detector or detectors. Other aspects are described and claimed.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: May 7, 2019
    Assignee: HACH COMPANY
    Inventors: Richard Edward Leggett, Wayne Boris Perdue, Andreas Mitreiter
  • Patent number: 10209244
    Abstract: A sample analyzer prepares a measurement sample from a blood sample or a body fluid sample which differs from the blood sample; measures the prepared measurement sample; obtains characteristic information representing characteristics of the components in the measurement sample; sets either a blood measurement mode for measuring the blood sample, or a body fluid measurement mode for measuring the body fluid sample as an operating mode; and measures the measurement sample prepared from the blood sample by executing operations in the blood measurement mode when the blood measurement mode has been set, and measuring the measurement sample prepared from the body fluid sample by executing operations in the body fluid measurement mode that differs from the operations in the blood measurement mode when the body fluid measurement mode has been set, is disclosed. A computer program product is also disclosed.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: February 19, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Takaaki Nagai, Noriyuki Narisada, Daigo Fukuma, Masanori Imazu
  • Patent number: 10156664
    Abstract: Provided are a mask inspection apparatus and a mask inspection method that can prevent a reduction in a reflectance of a drop-in mirror, which is caused by carbon contaminants. A mask inspection apparatus according to the present invention includes a drop-in mirror including multi-layer film and a reflective surface. The drop-in mirror is configured to reflect illumination light incident on the reflective surface and illuminate the mask. An area of the reflective surface is configured to be greater than an area of an illuminated spot irradiated with the illumination light on the reflective surface. The drop-in mirror is configured to be movable. A position of the illuminated spot on the reflective surface is configured to be moved when the drop-in mirror is moved.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: December 18, 2018
    Assignee: Lasertec Corporation
    Inventors: Kiwamu Takehisa, Hiroki Miyai
  • Patent number: 10113966
    Abstract: A blood analyzer comprises a light source unit configured to irradiate light on a measurement sample prepared from blood, a fluorescent light detecting unit configured to detect auto-fluorescence produced by red blood cells in the measurement sample which is irradiated by light, an information processing unit configured to obtain auto-fluorescence information related to red blood cells which produce auto-fluorescence detected by the fluorescent light detecting unit. The information processing unit is configured to make a determination regarding anemia based on the auto-fluorescence information.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: October 30, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Kazuhiro Yamada, Kazuhiro Sasaki, Seiichiro Tabata, Takeshi Yamamoto
  • Patent number: 9870612
    Abstract: A method includes inspecting a mask to locate a defect region for a defect of the mask. A phase distribution of an aerial image of the defect region is acquired. A point spread function of an imaging system is determined. One or more repair regions of the mask are identified based on the phase distribution of the aerial image of the defect region and the point spread function. A repair process is performed to the one or more repair regions of the mask to form one or more repair features.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: January 16, 2018
    Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.
    Inventors: Shinn-Sheng Yu, Anthony Yen, Wen-Chuan Wang, Sheng-Chi Chin
  • Patent number: 9823190
    Abstract: A particle counter for chemical solution in this disclosure uses a flow cell through which a chemical solution including particles flows, a laser light, and a light-receiving element array. Scattered light from the particles passing through a detection region on an optical path of the laser light in the flow cell is condensed to the light-receiving element array. The laser light in the center of the detection region has an energy density of 3×108 mW/cm2 or more. Each of plural light-receiving elements (a) is larger in length and width than a spot diameter of the scattered light, and (b) receives the scattered light from a region with a size of 760 ?m2 or less included in the detection region. The signal processing unit counts the particles passing through the detection region by use of a threshold corresponding to the smallest measurable particle size of 0.03 ?m.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: November 21, 2017
    Assignee: RION CO., LTD.
    Inventors: Takashi Minakami, Masaki Shimmura, Tomonobu Matsuda
  • Patent number: 9778179
    Abstract: Apparatus derives a sample liquid property and has a container with an outlet section having an overflow edge at a horizontal sample surface. A light source above the surface generates a probe light beam at a non-zero angle ?1 to a normal to the surface. A detector above the surface detects intensity of light emitted out through the surface along a first detection axis forming a non-zero angle ?1 with the surface. An optical barrier between the probe light beam and the first detection axis blocks reflected or scattered light. An inlet section receives sample liquid and has an opening to the main section beneath the sample surface. A separating member separates the sample surface of the inlet section from the sample surface of the main section.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: October 3, 2017
    Assignee: SWAN ANALYTISCHE INSTRUMENTE AG
    Inventor: Heinz Wagner
  • Patent number: 9459207
    Abstract: This invention enables high throughput detection of small molecule effectors of particle association, as well as quantification of association constants, stoichiometry, and conformation. “Particle” refers to any discrete particle, such as a protein, nucleic acid, carbohydrate, liposome, virus, synthesized polymer, nanoparticle, colloid, latex sphere, etc. Given a set of particle solutions having different concentrations, dynamic light scattering measurements are used to determine the average hydrodynamic radius, ravg, as a function of concentration. The series of ravg as a function of concentration are fitted with stoichiometric association models containing the parameters of molar mass, modeled concentrations, and modeled hydrodynamic radii of the associated complexes. In addition to the ravg value analysis, the experimental data may be fit/analyzed in alternate ways. This method may be applied to a single species that is self-associating or to multiple species that are hetero-associating.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: October 4, 2016
    Assignee: WYATT TECHNOLOGY CORPORATION
    Inventors: Amy D. Hanlon, Michael I. Larkin
  • Patent number: 9459208
    Abstract: A device and method for facilitating convenient measurement of airflow in a duct detector. The device may include a detector assembly and an airflow sensor mounted within the detector assembly. The airflow sensor may be coupled to a remote control device, such as via control circuitry. A method for testing airflow in the duct detector may be performed by measuring airflow in the detector assembly, generating a signal that corresponds to the measured airflow in the detector assembly, and determining whether the generated signal exceeds a predetermined threshold signal level. If the generated signal does not exceed the threshold signal level, alarms may be activated and/or blowers in a ventilation system may be deactivated.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: October 4, 2016
    Assignee: TYCO FIRE & SECURITY GMBH
    Inventors: Todd F. Orsini, Donald D. Brighenti, Anthony J. Capowski
  • Patent number: 9255890
    Abstract: An apparatus for measuring light scatter, the apparatus having a light transmitter and reception optics for transmitting and detecting a light beam scattered in a measured zone, respectively, wherein an adjustment unit changes between a measuring mode wherein the optical axes of the light transmitter and the reception optics stand at an angle with respect to one another and intersect in the measured zone and a test mode wherein the optical axes of the light transmitter and the reception optics are parallel, wherein the light beam successively sweeps over the reception optics. The reception optics is rotatably held at a displaceable rotary axle, wherein the adjustment unit first rotates the reception optics about the rotary axle in the test mode until the optical axis of the reception optics is parallel with the optical axis of the light transmitter and then displaces the rotatable axle together with the reception optics.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: February 9, 2016
    Assignee: SICK ENGINEERING GMBH
    Inventors: Uwe Melcher, Jürgen Regehr
  • Patent number: 9239405
    Abstract: A particle detection system is provided, including a sensing chamber having an inlet nozzle, an outlet nozzle, and an interrogation zone defined therebetween. Particles in a sampled environmental gas are prevented from escaping the interrogation zone by pressurizing the sensing chamber such that the pressure therein is higher than that in the outlet nozzle. This is accomplished by providing a source of extra gas to the sensing chamber, for example, by diverting gas from an inlet flow path directly to the sensing chamber.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 19, 2016
    Assignee: AZBIL CORPORATION
    Inventors: John H. Buchanan, III, Hisaya Murakami
  • Patent number: 9155517
    Abstract: An opto-electrical ultrasound sensor, preferably for the use in medical diagnostics, comprising at least one light source (2), a photo detector (3) illuminated by the light source (2) and capable of producing an electrical signal indicative of the intensity of the light incident on the photo detector (3), and an optical ultrasound detector (4) located in the optical path between the light source (2) and the photo detector (3) and capable of modulating in response to an ultrasound signal the intensity of at least part of the light incident on photo detector (3) from the light source (2). The opto-electrical ultrasound sensor further comprises intensity adjustment means (5) for adjusting the intensity of the light incident on the photo detector (3) via the optical ultrasound detector (4).
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: October 13, 2015
    Assignee: EZONO AG
    Inventors: Allan Dunbar, Eliseo Sobrino, Sicco Schets, Uwe Zeitner
  • Patent number: 9095851
    Abstract: A fluid control apparatus including a detecting unit including a light source for irradiating light toward a microfluidic device, and a photodetector for detecting light reflected from the microfluidic device, a transporting unit for moving the detecting unit; and a determining unit for controlling a transporting operation by the transporting unit, where determining a state of a fluid at a particular position relative to the microfluidic device is based on light reflected from the microfluidic device, and method of using same.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: August 4, 2015
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Won-seok Chung, Kak Namkoong, Chin-sung Park, Kyung-ho Kim, Joon-ho Kim
  • Patent number: 9091605
    Abstract: The force calculation system of the present invention is provided with: an air blowing unit for blowing air at a predetermined pressure; a flow passage for air blown from air blowing unit; a sensing unit for changing the ease of flow of air that flows through a flow passage by deforming when an external force is given; a storage unit for storing in advance the flow volume-force correspondence information showing the correspondence between the magnitude of the force received by the sensing unit and the flow volume at which air blown from air blowing unit flows through the flow passage; and a processing unit for calculating the magnitude of external force received by the sensing unit, on the basis of: the flow volume of air flowing through the flow passage as measured by a flow volume meter; and the flow volume-force correspondence information stored in the storage unit.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: July 28, 2015
    Assignee: Tokyo Institute of Technology
    Inventors: Kenji Kawashima, Kotaro Tadano, Daisuke Haraguchi
  • Patent number: 9019496
    Abstract: The invention relates to a method for estimating the amount of entities deposited on microparticles in suspension in a solution, and also to an associated device. The method comprises the following steps: (a) the solution is illuminated with a light source; (b) an optical signal formed by the scattering, in the solution, of the illuminating light is detected; (c) the optical signal obtained in step (b) is analyzed in order to obtain an indicator relating to this signal; (d) the indicator obtained in step (c) is compared with a reference indicator, obtained for a reference solution, the comparison making it possible to estimate the amount of entities deposited on the microparticles.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: April 28, 2015
    Assignees: Commissariat a l'Energie Atomique et aux Energies Alternatives, Sanofi Pasteur
    Inventors: Vincent Poher, Frederic Fantoni, Veronique Mourier, Philippe Peltie, Frederic Ronzon, Christian Valentin
  • Patent number: 8982345
    Abstract: In an apparatus for measuring an optical characteristic of a sample, one object of the present invention is to provide an apparatus capable of measuring hemispherical total reflectance, hemispherical total transmittance, and light distribution, and to achieve a reduction in measurement time and an improvement in precision of the quantitative analysis of hemispherical total reflectance (transmittance). In a double ellipsoidal optical system which is an optical system in which one focal points of two ellipsoidal mirrors are positioned as a common focal point, and three focal points are aligned in a straight line, the double ellipsoidal optical system is composed of a partial ellipsoidal mirror 2, such as a quarter ellipsoidal mirror, and a belt-shape ellipsoidal mirror 1.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: March 17, 2015
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Etsuo Kawate, Miroslav Hain
  • Publication number: 20150036121
    Abstract: The invention relates to a method for measuring the scattered light (L2) of particles (P, PK) in a measuring medium (F), wherein a measuring container (1) is supplied with the measuring medium (F) and incident light (L1) is shone through the measuring medium (F) at least in some regions over a certain path length (1) and in a certain direction and the light (L2) scattered from the incident light (L1) is measured within a certain angle range (?). It is provided according to the invention that the incident light (L1) is guided parallel to a longitudinal axis (S) of the measuring container (1). By these measures, known methods can be improved and it is readily possible to use the invention even for very small measuring volumes of the measuring medium (F) with the associated small dimensions of the measuring container (1).
    Type: Application
    Filed: July 2, 2012
    Publication date: February 5, 2015
    Applicant: BOEHRINGER INGELHEIM MICROPARTS GMBH
    Inventors: Dirk Kurowski, Christian Vesper, Gert Blankenstein
  • Patent number: 8877507
    Abstract: An automated method for assuring sample adequacy. The method includes providing a sample in a testing container, activating an illumination source to pass an illumination beam through the testing container and into the sample, and detecting an intensity of an emitted beam. The emitted beam includes at least a portion of the illumination beam that has been scattered by the sample. The method also includes generating a sample turbidity measurement based on the intensity of the emitted beam, and determining, based on the sample turbidity measurement, an adequacy of the sample to provide accurate results in a primary test.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: November 4, 2014
    Assignee: Qiagen Gaithersburg, Inc.
    Inventors: Jiulin Xia, Richard L. Mantefuel, Carl Theodore Edens, Jonathan Matthew Miller, Nadia P. Allen
  • Patent number: 8699028
    Abstract: A cell/particle analyzing device includes a light-emitting unit, a light-diverting unit, a first receiving unit and a second receiving unit. The light-emitting unit generates a first light beam. The light-diverting unit is connected to the light-emitting unit and has an input end, a bidirectional transceiving end and an output end. The input end receives the first light beam generated by the light-emitting unit. The bidirectional transceiving end transmits the first light beam generated by the light-emitting unit and receives a second light beam. The output end outputs the second light beam. The first receiving unit is connected to the output end of the light-diverting unit and receives the second light beam. The second receiving unit is aligned with the bidirectional transceiving end.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: April 15, 2014
    Assignee: National Pingtung University of Science and Technology
    Inventors: Yao-Nan Wang, Lung-Ming Fu, Chang-Hsien Fu, Chien-Hsiung Tsai
  • Patent number: 8675195
    Abstract: A device and process for determining sizes of particles of a particle stream. A first optical measuring system with a first dot matrix sensor and a lighting device, which transilluminates the measuring volume are provided. The first dot matrix sensor and the lighting device form a transmitted-light arrangement. The computing device determines projection areas of particles within the transilluminated measuring volume from the image data of the first dot matrix sensor. The optical measuring arrangement includes a second optical measuring system with a second dot matrix sensor for detecting the diffraction pattern of the particles. The computing device determines a size distribution of the particles in the measuring volume based on the projection areas and the diffraction pattern. The computing device forms the size distribution from particle sizes determined on the basis of the projection areas and from particle sizes determined on the basis of the diffraction pattern.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: March 18, 2014
    Assignee: Baumer Optronic GmbH
    Inventors: Joachim Ihlefeld, Amer Tarraf
  • Patent number: 8531516
    Abstract: This invention relates to measuring the light that is scattered from particulates (aerosols) in a gas or liquid. The sample typically flows into the instrument and the particulates are measured in-situ. The intensity of the scattered light is measured at many different angles, which determines both the amount of particulates in the sample, and detailed information about the particles such as average size, shape and composition. The measurement can be applied to climate and air pollution research, and clean room monitoring.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: September 10, 2013
    Assignee: The United States of America as Represented by the Secretary of Commerce
    Inventor: John Edward Barnes
  • Patent number: 8467040
    Abstract: A method, apparatus, and system for a sorting flow cytometer include an objective lens having an optical axis coaxially aligned with the flow path at the focal point. A controllable energy source selectively alters an analyte according to a determination of whether the analyte is in a desired sub-population. In various embodiments, one or both of the emission from the controllable energy source and/or the emission from an illumination energy source passes through the objective lens. In some embodiments in which the emission from the controllable energy source passes through the objective lens, the objective lens may focus the emission from the controllable energy source at a different point than the focal point of a signal detected from the analyte and, in particular, at a point closer to the objective lens.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: June 18, 2013
    Assignee: Microbix Biosystems, Inc.
    Inventor: Mark Luscher
  • Publication number: 20130016335
    Abstract: Techniques, devices and systems are disclosed for characterizing particles in a fluid sample by optical space-time coding. In one aspect, a microfluidic device for optical detection of particles includes a substrate, a microfluidic channel formed on the substrate and structured to carry a fluid sample containing particles, in which the microfluidic channel is structured to transmit a probe light, and a mask formed on one side of the microfluidic channel and structured to include a pattern of openings along the microfluidic channel, in which at least two of the openings have varying dimensions across the microfluidic channel, and in which the pattern of openings encodes a waveform on the probe light that transmits through the microfluidic channel to allow optical detection of a position of a particle in the microfluidic channel.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 17, 2013
    Inventors: Yu-Hwa Lo, Tsung-Feng Wu, Zhe Mei
  • Patent number: 8213010
    Abstract: Measuring and tracking velocity of individual aerosol particles in a bio-threat detection system are accomplished using a single beam laser source in combination with a birefringent crystal that splits the laser beam into two beams having orthogonal polarization. Scattered light is collected with an elliptical reflector and directed into two detection channels, sampling total elastic scatter in the first channel and sampling polarized elastic scatter in the second channel. The difference in intensity of the scattered light in the polarized channel is used to identify the position of the particles. By taking the ratio of signal output from the polarized detector to the total scatter detector, a threshold level can be established to determine the presence of particles traversing the two beams. The particles are time stamped as they traverse the two beams and the time difference between the pulses can be used to measure the velocity of the particles.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: July 3, 2012
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventor: Vasanthi Sivaprakasam
  • Patent number: 8209128
    Abstract: This invention provides a new method for rapidly analyzing single bioparticles to assess their material condition and state of health. The method is enabled by use of a resonant cavity apparatus to measure an optical property related to the bioparticle size and refractive index. Measuring the refractive index is useful for determining material properties of the bioparticle. The material properties depend on the biomolecular composition of the bioparticle. The biomolecular composition is, in turn, dependent on the state of health of the bioparticle. Thus, measured optical properties can be used to differentiate normal (healthy) and abnormal (diseased) states of bioparticles derived from cells or tissues. The method is illustrated with data obtained from a resonator with a gain medium. The invention also provides new methods for making multiple measurements in a single device and detecting, analyzing, and manipulating bioparticles that are much smaller than the wavelength of light.
    Type: Grant
    Filed: February 20, 2008
    Date of Patent: June 26, 2012
    Inventor: Paul L. Gourley
  • Patent number: 8035815
    Abstract: Disclosed herein is an optical detection method and optical detection apparatus, the apparatus including: a light irradiation section configured to irradiate a laser beam upon one of fine particles which are successively fed in a flow path; and a light detection section configured to detect fluorescent light and/or scattered light generated from any of the fine particles upon which the laser beam is irradiated; the method including the steps of: irradiating a laser beam upon one of fine particles which are successively fed in a flow path; and detecting fluorescent light and/or scattered light generated from the fine particle; wherein the laser beam being formed as a pulse laser beam whose pulse intensity is modulated such that one laser beam or two or more laser beams having different wavelengths are irradiated by a plural number of times upon one fine particle with the intensity varied.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: October 11, 2011
    Assignee: Sony Corporation
    Inventors: Masataka Shinoda, Shingo Imanishi
  • Patent number: 8029661
    Abstract: The determination of wax crystal particle size and population is used to monitor the performance of wax crystallizers used in lubricant oil processing using solvent dewaxing. The wax crystal particle size is monitored using online measurements. The information obtained from on-line monitoring is then used to control crystallization in the dewaxing equipment in order to optimize performance of the dewaxing units.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: October 4, 2011
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Thomas R. Palmer, Brent E. Beasley, David S. Sinclair
  • Patent number: 8018582
    Abstract: Provided is a detection apparatus of Raman scattering and light scattering, and more particularly, a simultaneous detection apparatus of Raman scattering and dynamic light scattering and a detection method using the same. The simultaneous detection apparatus of Raman scattering and light scattering includes: a detection unit for applying incident light to a sample, and detecting Raman scattering in 90° or 180° geometry and light scattering in 90° or 180° geometry in order to simultaneously collect Raman scattering and light scattering; and a computer connected to the detection unit to obtain at least one of the size and distribution of particles from the detected light scattering, and to obtain information of the molecular structure from the detected Raman scattering.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: September 13, 2011
    Assignee: SNU R&DB Foundation
    Inventors: Dae-Hong Jeong, Yoon-Sik Lee, Myung-Haing Cho, Yong-Kweon Kim
  • Patent number: 8004661
    Abstract: A method, apparatus, and system for a sorting flow cytometer include an objective lens having an optical axis coaxially aligned with the flow path at the focal point. A controllable energy source selectively alters an analyte according to a determination of whether the analyte is in a desired sub-population. In various embodiments, one or both of the emission from the controllable energy source and/or the emission from an illumination energy source passes through the objective lens. In some embodiments in which the emission from the controllable energy source passes through the objective lens, the objective lens may focus the emission from the controllable energy source at a different point than the focal point of a signal detected from the analyte and, in particular, at a point closer to the objective lens.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: August 23, 2011
    Assignee: Microbix Biosystems Inc.
    Inventor: Mark Luscher
  • Publication number: 20110187850
    Abstract: This invention relates to measuring the light that is scattered from particulates (aerosols) in a gas or liquid. The sample typically flows into the instrument and the particulates are measured in-situ. The intensity of the scattered light is measured at many different angles, which determines both the amount of particulates in the sample, and detailed information about the particles such as average size, shape and composition. The measurement can be applied to climate and air pollution research, and clean room monitoring.
    Type: Application
    Filed: February 3, 2010
    Publication date: August 4, 2011
    Applicant: United States Government, as represented by the Secretary of Commerce
    Inventor: John Edward Barnes
  • Patent number: 7916280
    Abstract: The present invention provides a blood analyzer. The blood analyzer comprises a flow cell in which a first measurement sample flows, a light source for irradiating the first measurement sample flowing in the flow cell, a PIN photodiode for detecting a side scattered light from the first measurement sample irradiated by the light source, and an avalanche photodiode for detecting a side fluorescence light from the first measurement sample irradiated by the light source. The blood analyzer also comprises a signal processing part which has a low pass filter for reducing high frequency noise included in the side fluorescent light signal. A cut-off frequency of the low pass filter is set so that the blood analyzer can classify white blood cells in the first measurement sample into at least four groups comprising neutrophils, lymphocytes, monocytes, and eosinophils, based solely on the side scattered light signal and the side fluorescent light signal.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: March 29, 2011
    Assignee: Sysmex Corporation
    Inventors: Kunio Ueno, Yuichi Hamada
  • Patent number: 7830510
    Abstract: The present disclosure has an apparatus for detecting fibers in a gas flowing along a passageway. A laser beam is provided at one end of the passageway and the beam is directed along a length of the passageway through which the gas flows. An electrode system, as disclosed, a quadrupole electrode system is mounted along the passageway to cause fibers carried in the gas to oscillate in a detection zone. A photo detector is positioned laterally of the passageway and detects light scattered by the oscillating fibers and projected through an opening in the passageway to provide an output signal that is a function of the light scattered by the fibers in the detection zone.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: November 9, 2010
    Assignee: MSP Corporation
    Inventors: Benjamin Y. H. Liu, William D. Dick, Francisco J. Romay, Mark J. Battista, Pedro Lilienfeld
  • Publication number: 20100182590
    Abstract: A measuring device for quantitative determination of optical characteristic values for detecting photo- and/or electrochemical decomposition reactions taking place on surfaces of photocatalytically active substrates.
    Type: Application
    Filed: June 25, 2007
    Publication date: July 22, 2010
    Applicant: Fraunhofer-Gesellschaft zur Fordenrung der angewandten Forschung e.V.
    Inventors: Frank Neumann, Thomas Neubert, Michael Vergöhl
  • Patent number: 7709271
    Abstract: The present invention relates to a method and a device for determining a concentration of a biological active substance in a sample by the means of an enzyme-linked immunosorbent assay (ELISA). The device comprises a solid support within a tubing for binding an immunosorbent and an inlet for fluids, a detector for detecting radiation due to an activity in the tubing, wherein the tubing is arranged inside a microchip extending substantially in one plane, for conducting the fluids along the plane of the microchip. The tubing forms a reaction cell having a large detection area. The reaction cell of the microchip is arranged perpendicular to the detector. The method comprises the steps of introducing the fluids into the tubing, conducting the fluids through the tubing forming a reaction cell, in which reaction cell the radiation emitting activity takes place, and detecting the light emitted from the reaction cell substantially perpendicular to the plane.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: May 4, 2010
    Assignee: Prolight Diagnostics AB
    Inventor: Masoud Khayyami
  • Patent number: 7667840
    Abstract: The present invention provides a particle measuring system which is provided in a processing system that generates an atmosphere obtained by exhausting air or a gas in a processing chamber by a vacuum pump and applies a process concerning semiconductor manufacture to a wafer W in the atmosphere, attached to an exhaust pipe which connects an exhaust opening of the processing chamber with the vacuum pump, and measures the number of the particles in the exhaust gas, and a measuring method thereof, the system and method providing a processing system and a cleaning method which terminate etching process by determining an end point based on the number of the particles in the exhaust gas and perform cleaning of unnecessary films.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: February 23, 2010
    Assignee: Tokyo Electron Limited
    Inventors: Hayashi Otsuki, Tsukasa Matsuda, Kyoko Ikeda
  • Patent number: 7663751
    Abstract: The specific wavelength of 525 nm is described as a single monochromatic light source used in the determination of turbidity by nephelometry at 90° for particulate matter in raw water, water treatment, waste water treatment and industrial process streams. This wavelength improves the detection of smaller particle concentration in water where light scattering characteristics of shorter wavelengths are superior to light sources using longer wavelengths.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: February 16, 2010
    Inventor: Herbert Leckie Mitchell
  • Patent number: 7658884
    Abstract: The apparatus for deriving at least one property like turbidity or fluorescence of a sample liquid from measuring emitted light emitted from said sample liquid upon irradiation of said sample liquid with a probe light beam comprises a container for containing said sample liquid, said sample liquid forming a sample surface. It furthermore comprises a light source for generating said probe light beam directed, in an angle ?1?0° with respect to a sample surface normal, at said sample surface, and a detector adapted to detecting an intensity of said emitted light emitted through said sample surface out of said sample liquid generally along a first detection axis, said first detection axis forming an angle ?1?0° with a sample surface normal.
    Type: Grant
    Filed: October 5, 2005
    Date of Patent: February 9, 2010
    Assignee: Swan Analytische Instrumente AG
    Inventor: Heinz Wagner