Abstract: The disclosure relates to stent detection and shadow detection in the context of intravascular data sets obtained using a probe such as, for example, and optical coherence tomography probe or an intravascular ultrasound probe.

Abstract: A distance measuring sensor includes: a light source having a semiconductor optical amplifier and a resonator with a silicon photonic circuit, which are at a semiconductor substrate; a plurality of emitters, each emitter configured to emit a light beam generated by the light source to outside of the light source; a scanner configured to perform scanning with the light beam by enabling the light beam emitted from the light source to be reflected at a mirror and vibrating the mirror; an optical receiver configured to receive a reflected light beam, which is generated by the light beam reflected at the object; and a processor configured to measure the distance to the object based on the reflected light beam received at the optical receiver. Light beams respectively emitted from the emitters are incident on the mirror in different directions. The scanner performs scanning different regions with the respective light beams.

Abstract: A digital measuring device implemented on a photonic integrated circuit, the digital measuring device including a tunable laser source implemented on the photonic integrated circuit configured to sweep over a frequency range to provide multi-wavelength light, a first waveguide structure implemented on the photonic integrated circuit configured to direct a first portion of light from the laser source at a moving object and receive light reflected from the moving object, a second waveguide structure implemented on the photonic integrated circuit configured to combine a second portion of light from the laser source with the light reflected from the moving object to produce a measurement beam, and a first detector implemented on the photonic integrated circuit configured to detect intensity values of the measurement beam to measure a distance between the digital measuring device and the moving object.

Abstract: Methods and systems for focusing and measuring by mean of an interferometer device, having an optical coherence tomography (OCT) focusing system, by separately directing an overlapped measurement and reference wavefront towards a focus sensor and towards an imaging sensor; where a predefined focusing illumination spectrum of the overlapped wavefront is directed towards the focus sensor, and where a predefined measurement illumination spectrum of the overlapped wavefront is directed towards the imaging sensor. Methods and systems for maintaining focus of an interferometer device, having an OCT focusing system, during sample's stage moves.

Abstract: Disclosed is a device and a method for measuring Fabry-Parot (FP) transmittance curve by using a whispering gallery mode laser source. The device includes: a seed laser, a first polarizer, a second polarizer, a spectroscope, a beam reduction system, a lens, and Polydimethylsiloxane (PDMS) microfluidic chip arranged in sequence.

Abstract: Methods, devices and systems are described that use a combination multiple light sources having different coherence lengths to measure surface characteristics of an object. One example system includes a two laser sources configured to operate at a first and a second center wavelength, a broadband source configured to operate at a range of wavelengths outside of the operating range of the at least two lasers, a phase mask array and a color filter arranged, respectively, to impart different phase delays and provide spectral filtering corresponding to the emitted radiation from the sources. A pixelated sensor device is positioned to simultaneously measure intensity values associated with a plurality of interferograms formed due to interference of light from the light sources after propagation through the phase mask array and the color filter. The measured intensity values enable the determination of surface characteristics of the object.

Abstract: In some embodiments, a SCAPE system routes light from a tilted intermediate image plane to an infinity space disposed behind a third objective. A first beam splitter positioned in the infinity space routes light from the intermediate image plane with different wavelengths in different directions. First and second light detector arrays capture first and second wavelength images, respectively, and optical components route light having the first and second wavelength towards the first and second light detectors, respectively. In some embodiments, a SCAPE system is used to capture a plurality of images while a sample is perturbed (e.g., vibrated, deformed, pushed, pulled, stretched, or squeezed) in order to visualize the impact of the perturbation on the sample.

Abstract: Systems and methods for dynamic locking of optical path times using entangled photons are provided. A system includes an optical source for generating bi-photons; tracer laser beam sources for generating tracer laser beams; telescopes that emit the tracer laser beams and the bi-photons to remote reflectors, each bi-photon traveling along an optical path in a pair of optical paths toward a corresponding remote reflector, wherein the telescopes receive reflected bi-photons from the remote reflectors; and communication links, wherein the optical source respectively communicates with first and second remote reflectors through a first and second communication link. Also, the optical source uses the tracer laser beams and the communication links to respectively point the bi-photons towards the remote reflectors.

Abstract: An optical coherence tomographic (OCT) system includes a sample arm, a reference arm and an OCT probe. The probe irradiates a bodily lumen and a fluid contained within the bodily lumen with light of a sample beam transmitted through a double-clad fiber (DCF). A first detector detects light of a reference beam and light reflected from the bodily lumen and propagated through the core of the DCF to generate OCT interference signals. Light backscattered by the bodily lumen and by the fluid contained in the bodily lumen is propagated through a cladding of the DCF and detected by a second detector to generate an intensity signal. A processor analyzes the intensity signal, and triggers a pullback of the probe and initiates recording of OCT images of the bodily lumen in response to the intensity the backscattered light reaching a predetermined threshold value.

Abstract: An OCT imaging method of some exemplary aspects includes acquiring a first three dimensional data set by applying an OCT scan targeting a first three dimensional region of a sample, creating a first two dimensional map based on representative intensity values respectively of a plurality of pieces of A-scan data included in the first three dimensional data set, designating a second three dimensional region of the sample based on the first two dimensional map, acquiring a second three dimensional data set by applying an OCT scan targeting the second three dimensional region, and generating image data from at least part of the second three dimensional data set.

Abstract: A non-invasive optical detection system and method are provided. Sample light is delivered into a target volume of interest, whereby the sample light is scattered by the target volume of interest, resulting in a sample light pattern that exits the anatomical structure. Reference light is combined with the sample light pattern to generate at least one interference light pattern, each of which may have a time varying interference component that integrates to a first value in the absence of the physiological event, and that integrates to a second greater value in the presence of the physiological event. Intensities of spatial components of each interference light pattern are detected during a measurement period. A function of the detected spatial component intensities of the interference light pattern(s) is analyzed, and a presence of the physiological event in the target volume of interest is determined based on the analysis.

Abstract: A system includes a laser (1) operative to emit a light beam, a beam splitter (2) arranged to split the light beam into a first beam and a second beam, the first beam being directed to a nonlinear converter (8) that generates a signal beam having a Stokes-shifted wavelength, a recombiner (9) arranged to recombine the signal beam with the second beam to form a recombined beam which is directed to a tapered optical fiber (5) located within a material to be monitored, and a detector (7) arranged to detect light emitted by the tapered optical fiber (5) and which uses stimulated Raman spectroscopy to detect a chemical in the material.

Abstract: The invention relates to an OCT system with an OCT light source for emitting OCT light into an object beam path and a reference beam path. The system comprises a detector for detecting an interference signal produced by the object beam path and the reference beam path. A polarization-dependent delay element is arranged in the object beam path. The invention also relates to a corresponding OCT method. The invention allows the effects of parasitic reflections to be reduced.

Abstract: A retinal structure and function forecasting method, system, and computer program product include producing an enriched feature representation of clinical measurements and clinical data combined with optical coherence tomography (OCT) data, training a forecasting model with the enriched feature representation, and forecasting a retinal structure at a forecast date based on the trained forecasting model.

Abstract: In an OCT imaging, a focus position in a tomographic image is determined by a first distance, a second adjustment amount, a third adjustment amount and a refractive index of a medium. The first distance is a distance between a first surface and a second surface of a wall part of a container. The second adjustment amount is a focus position adjustment amount of an objective optical system at which an intensity of reflected light from the second surface is maximized when a reference mirror is positioned at a position where an object optical path length to the first surface and a reference optical path length are equal in a condition that the objective optical system is focused on the first surface. The third adjustment amount is a focus position adjustment amount in the imaging.

Abstract: Optical coherent receiver arrays are described. The optical coherent receiver arrays include an integrated array of photodetectors separated by integrated mirrors which may cause interference of received free space optical and local oscillator signals. The mirrors may serve as splitters, helping to align the received signal and local oscillator to cause interference. The photodetectors of the optical coherent receiver array may be electrically coupled in various manners to read out the signals. The optical coherent receiver array may be implemented in an optical coherence tomography (OCT) imaging system in some embodiments.

Abstract: Disclosed herein is a laser ultrasonic testing (UT) apparatus for inspecting a surface of an object. The laser UT apparatus comprises an excitation laser, which is selectively operable to generate an excitation laser beam. The laser UT apparatus also comprises a first acousto-optic deflector (AOD) and a second AOD. The laser UT apparatus additionally comprises a detection laser, which is selectively operable to generate a detection laser beam. The laser UT apparatus further comprises a third AOD and a fourth AOD.

Abstract: In certain embodiments, a system for controlling a position of a focal point of a laser beam comprises a beam expander, a scanner, an objective lens, and a computer. The beam expander controls the focal point of the laser beam and includes a mirror and expander optical devices. The mirror has a surface curvature that can be adjusted to control a z-position of the focal point. The expander optical devices direct the laser beam towards the mirror and receive the laser beam reflected from the mirror. The scanner receives the laser beam from the beam expander and manipulates the laser beam to control an xy-position of the focal point. The objective lens receives the laser beam from the scanner and directs the beam towards the target. The computer receives a depth instruction, and sets actuation parameters to control the surface curvature of the mirror according to the depth instruction.

Abstract: A laser device includes a laser configured to generate laser light and a laser control module configured to receive at least a portion of the laser light generated by the laser, to generate a control signal and to feed the control signal back to the laser for stabilizing the frequency, wherein the laser control module includes a tunable frequency discriminating element which is preferably continuously frequency tunable, and where the laser control module is placed outside the laser cavity.

Abstract: Interferometer system, including optical means (2, 3, 4, 5) arranged for directing light along a first interferometer path and (separate) second interferometer path, and for combining the light for allowing interferometry, characterized in that the first interferometer path (PI) is provided with a first light transmitting structure (10) having a rotational position that is adjustable with respect to an optical axis of the first path.

Abstract: An image classification method, a computer device, and a medium are disclosed. The method includes: acquiring a middle-level semantic feature of an image to be classified through a visual dictionary; and classifying the image to be classified according to the middle-level semantic feature of the image to be classified using a classification model based on middle-level semantic features.

Abstract: An image acquisition apparatus includes a light source configured to emit light, a dividing unit configured to divide the light from the light source into reference light and measurement light, an image forming unit configured to form a tomographic image of a subject based on interfered light in which return light from the subject irradiated with the measurement light and the reference light are interfered, a focus adjusting unit configured to adjust a focus of the measurement light, an optical-path-length adjusting unit configured to adjust an optical path length of the reference light, and a control unit configured to adjust the optical path length of the reference light by controlling the optical-path-length adjusting unit according a change in an optical path length of the measurement light caused by adjustment of the focus using the focus adjusting unit.

Abstract: Provided is a brain function measurement device capable of improving the reliability of brain function measurement using a simple configuration. The brain function measurement device includes light source probes LD2 and LD12 for irradiating the scalp of a test subject with light beams; linearly polarizing films P2 and P3 for polarizing the light beams emitted from the light source probes LD2 and LD12 in a first direction; a linearly polarizing film P1 for blocking components in the first direction of reflected light beams that are generated as the light beams emitted from the linearly polarizing film P2 and P3 are reflected by the hairs of the test subject; and a detection probe PD1 for detecting the intensity of a light beam that has passed through the linearly polarizing film P1.

Abstract: Disclosed herein are interferometric measurement systems and methods. In one exemplary embodiment an interferometric measuring system for measuring the distance to or displacement of an object includes: a light source; an interferometer with a measuring arm and a reference arm; a dispersive medium; and a detector. The interferometer is disposed between the light source and the object. The dispersive medium is arranged to unbalance the dispersion between the measurement arm and the reference arm. The detector is arranged to detect spectrum interference from the interferometer. In one example, the dispersive medium is a chirped fiber Bragg grating. In another example, the dispersive medium is a highly dispersive optical fiber. In one example, the light source is a broadband light source, and the detector includes a spectrometer. In another example, the light source is a wavelength swept laser, and the detector includes a photodetector or a balanced photodetector.

Abstract: A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source.

Abstract: An ophthalmologic apparatus is configured to control an optical scanner so as to perform a scan by measurement light in an intersecting direction which intersects a traveling direction of the measurement light, to specify a scan length based on a detection result of interference light corresponding to the scan, the detection result being acquired by an interference optical system, the scan length being a length of a scan range in the intersecting direction within a characteristic region in an anterior segment of the subject's eye, and to specify a movement amount of the subject's eye based on a reference value of the characteristic region and the scan length.

Abstract: Techniques are disclosed related to recording a magnetic resonance image data set of a region of a patient with a magnetic resonance device using a multislice imaging technique. The multislice technique may be applied simultaneously with at least partial undersampling in a slice plane. The magnetic resonance data may be read out from a set of excited slices simultaneously and, by means of a slice separation algorithm that is calibrated using reference data recorded in a separate reference scan, may be allocated to the simultaneously read-out slices. Subsequently, an undersampling algorithm compensating for the undersampling in the slice plane may be applied to the undersampled magnetic resonance data of the individual slices.

Abstract: A three-dimensional measurement device includes: an optical system that splits incident light into two lights and radiates lights to a measurement object and to a reference surface, and recombines the two lights to emit combined light; a first irradiator that emits first light including first polarized light and entering a first surface; a second irradiator that emits second light including second polarized light and entering a second surface; a first imaging system to which the first output light enters wherein the first output light is emitted from the first surface when the first light enters the first surface; a second imaging system to which the second output light enters wherein the second output light is emitted from the second surface when the second light enters the second surface; and an image processor that performs three-dimensional measurement based on interference fringe images obtained by the first and second imaging systems.

Abstract: A catheter system for optical coherence tomography includes an elongate catheter body, an optical fiber in the elongate catheter body, and an anamorphic lens assembly coupled with a distal end of the optical fiber. The optical fiber and the lens assembly are together configured to provide a common path for optical radiation reflected from a target and from a reference interface between the distal end of the optical fiber and the lens assembly.

Abstract: A system and method for surface inspection of an object using optical coherence tomography (OCT) with anticipatory depth of field adjustment is provided. The method includes determining a present working distance and one or more forward working distances; determining a present depth of field in which the surface of the object is in focus at the location of the present working distance and at as many of the consecutive forward surface locations as determined possible; changing to the present depth of field; performing an A-scan of the object; moving the object such that the scanner head is directed at each of the consecutive forward surface locations determined to be in the present depth of field; and performing an A-scan at each of the consecutive forward surface locations determined to be in the present depth of field.

Abstract: An OCT (Optical Coherence Tomography) handheld device is provided comprising: a housing configured for handheld OCT scanning during a surgical procedure, the housing comprising an OCT scanning end and a proximal end opposite the OCT scanning end; an OCT scanning device inside the housing, the OCT scanning device configured for one or more of OCT polarized scanning and Doppler OCT scanning from the OCT scanning end, the OCT scanning device further configured to receive and convey OCT light between the proximal end and an OCT analysing system; and a tip extending from the OCT scanning end, the tip being removably attached to the OCT scanning end, the tip configured to receive and collect the OCT light therethrough. The OCT handheld device is configured to be removably draped around the tip, for use in the surgical procedure.

Abstract: An optical probe for detecting a biological tissue includes a surface imaging module and a tomography capturing module. The surface imaging module captures and creates a surface image of the biological tissue, and at least includes a light source emitting a first detecting light. The tomography capturing module captures a tomography image of the biological tissue and receives a second detecting light. The first detecting light passes via a first optical path from the light source to an imaging sensor through the biological tissue, a telecentric lens, a first optical mirror, and a lens assembly in sequence. The second detecting light passes via a second optical path from a first collimator to the first collimator through a scanner, the first optical mirror, the telecentric lens, the biological tissue, the telecentric lens, the first optical mirror, the scanner, and the first collimator in sequence.

Abstract: To provide a reflected light measurement device capable of efficiently performing disconnection inspection on an optical connector, and a plurality of optical fibers. The reflected light measurement device 1 includes a laser light source 2, a beam splitter 3 that branches measurement laser light L into measurement laser light L1 to be transmitted and reference laser light L2 to be reflected, a reference mirror 4 including an optical path length varying mechanism capable of adjusting an optical path length of the reference laser light L2, an optical path length switching unit 5, and switches the optical path length of the reference laser light L2 to a plurality of fixed lengths, and a photometer 6 that receives measurement laser light L1? reflected at defect sites D1 and D2 such as disconnection inside connectors C1 and C2, and reference laser light L2? reflected by the reference mirror 4.

Abstract: Systems and methods for stereo-polarimetric compressed-sensing ultrafast imaging.

Abstract: Techniques for generating an overlay map on a digital medical image of a slide are provided, and include cell detection and tissue classification processes. Techniques include receiving a medical image, separating the image into tiles, and performing tile classifications and tissue classifications based on a multi-tile analysis. Techniques additionally include identifying cell objects in the image, separating the image into and displaying polygons identifying the cell objects and cell classifications. Generated displays may be overlays over the initial digital image.

Abstract: An information processing apparatus includes an acquisition unit configured to acquire a plurality of data sets each of which includes a plurality of pieces of tomographic data that represents a section of a fundus, the plurality of data sets not including the same tomographic data as each other, a first generation unit configured to generate at least one motion contrast image from each of the plurality of data sets acquired by the acquisition unit, without generating a motion contrast image from across the data sets acquired by the acquisition unit, and a second generation unit configured to generate a single motion contrast image representing a cross section at a predetermined position in the fundus, based on the motion contrast image generated from at least one of the plurality of data sets.

Abstract: Apparatus and methods for determining information about at least one particle by measuring light scattered from the particles. Scattered light is combined with light from a light source to produce an optical interference signal utilizing a plurality of beam splitting functions. Scattered light signals are corrected for signal components which are not derived from particle scatter.

Abstract: Various methods and systems for improved anterior segment optical coherence tomography (OCT) imaging are described. One example method includes collecting a set of OCT data of the cornea of the eye; segmenting the set of OCT data to identify one or more corneal layers; fitting a two-dimensional model of corneal surfaces to the one or more corneal layers; determining motion-correction parameters by minimizing error between the one or more corneal layers and the two-dimensional model of the corneal surfaces; and creating a motion-corrected corneal image dataset from the set of OCT data using the motion-correction parameters. The motion-corrected corneal image dataset can be used to create a model of the anterior and/or posterior surfaces of the cornea. The model of the cornea is used to generate high density and motion-artifact free epithelial thickness maps, which are used for identifying or quantifying pathology such as keratoconus.

Abstract: A lightfield otoscope includes a housing with a tip configured to receive a disposable speculum. The otoscope also includes a microlens array, a sensor array and an optical train contained within the housing. The optical train includes an objective lens and a relay lens. The objective lens is positioned at least partially within the tip. The relay lens is used to relay an image plane of the objective lens to the microlens array and to relay a pupil plane of the objective lens to the sensor array. An active heating element is also contained within the housing and positioned to heat the front surface, thereby reducing fogging and/or condensation on the front surface.

Abstract: A fiber coupling device (100) includes the following components: a wedge plate (102) for receiving light and refracting the light in a predetermined direction, a condenser lens (104) for collecting the light refracted by the wedge plate (102); and an optical fiber (107) having an incident surface for receiving the light collected by the condenser lens (104). The wedge plate (102) is held rotatable around the optical axis (200) of the light incident on the wedge plate (102). The light refracted by the wedge plate (102) and collected by the condenser lens (104) is incident on a different point on the incident surface depending on the rotation angle of the wedge plate (102).

Abstract: A technique that can maximize signal to noise ratio in systems that use beam steering, by steering both the transmit and receive signals. A beam splitter is used, which is positioned to receive both the light beam transmitted by the light source and the return light beam, and a scanning beam steerer, which is positioned to receive both transmitted light from the beam splitter and returning light from the target. Using a split portion of the beam, a reference signal can be provided to probe the ambient condition of the sensor, to sense conditions such as darkness and fog.

Abstract: A position encoder for monitoring relative movement between a first object and a second object includes a grating that is coupled to the first object, and an image sensor assembly that is coupled to the second object. The image sensor includes a first image sensor; a second image sensor that is spaced apart from the first image sensor; an optical element that includes a first optical surface and a second optical surface that is spaced apart from the first optical surface; and an illumination system.

Abstract: An optical receiver is provided that includes an array of photoreceivers. Each photoreceiver may be configured to receive a respective portion of a speckle pattern generated by interaction between an object beam and a scattering medium and each photoreceiver may be configured to generate respective electrical detection signals for provision to processing circuitry for summing of the electrical detection signals. A photoreceiver may include a collector, first detector and second detectors, and first and second optical splitters. The photoreceiver may be configured to generate a first electrical detection signal and a second electrical detection signal based on a received portion of the speckle pattern.

Abstract: A method of processing optical coherence tomography (OCT) scans through a subject's skin, the method comprising: receiving a plurality of scans through the subject's skin, the scans representing an OCT signal in slices through the user's skin at different times; comparing the scans to determine time-varying regions in the scans; determining a depth-distribution of the time varying regions.

Abstract: A thickness measuring apparatus for measuring a thickness of a wafer includes a light source emitting light having a transmission wavelength region to the wafer, a focusing unit applying the light emitted from the light source to the wafer held on a chuck table, an optical branching section branching the light reflected on the wafer held on the chuck table, a diffraction grating diffracting the reflected light branched by the optical branching section to obtain diffracted light of different wavelengths, an image sensor detecting an intensity of the diffracted light obtained by the diffraction grating to produce a spectral interference waveform, and a computing unit computing the spectral interference waveform produced by the image sensor to output thickness information.

Abstract: An improved hyperspectral Raman imaging system and device that obtains full scale Raman images from a sample surface in seconds, wherein the dichromic mirror is located between the objective lens and sample surface. The laser is delivered to the sample surface and the Raman image is collected and transmitted through optic fiber to a camera after filtration. By delivering the laser to the sample without going through the objective lens, a high-power laser can safely illuminate the full field of view of the objective lens, allowing for safe Raman imaging within seconds. This fast and safe Raman imaging system can be used for, among other applications, the early detection of dental caries in practical settings.

Abstract: An optical coherence tomography (OCT) system includes: a light source; a multi-focal delay line; and a light detector. The multi-focal delay line includes: a positive lens; and an optical switch configured to: receive a light from the light source; selectively direct the sample light to the positive lens via a selected one of a plurality of light interfaces each located a different distance from the focal plane of the positive lens; and direct the sample light to an object to be measured. The light detector is configured to receive return light returned from the object to be measured in response to the sample light, and to receive a reference light produced from the light from the light source, and in response thereto to detect at least one interference signal. An associated OCT method may be performed with the OCT system.

Abstract: An imaging apparatus is disclosed for diagnosis including a plurality of transmitting and receiving units, an error of a scale of a tomographic image to be generated is reduced. The imaging apparatus can include including acquisition means for acquiring a propagation velocity of an ultrasound signal of a flushing liquid, generation means for generating ultrasound line data based on the propagation velocity of the ultrasound signal in a blood vessel tissue, and conversion means for converting positional information of each position within a range in which the flushing liquid flows regarding the ultrasound line data generated by the generation means based on a ratio between the propagation velocity in the blood vessel tissue and the propagation velocity in the flushing liquid. A tomographic image of a blood vessel is constructed by using the ultrasound line data converted by the conversion means.

Abstract: An apparatus includes: an acquisition unit configured to acquire pieces of three-dimensional data of a subject eye obtained at different times, the three-dimensional data including pieces of two-dimensional data obtained at different positions; a first planar alignment unit configured to perform first planar alignment including alignment between the pieces of three-dimensional data in a plane orthogonal to a depth direction of the subject eye; a first depth alignment unit configured to perform first depth alignment including alignment between pieces of two-dimensional data in at least one piece of three-dimensional data among the pieces of three-dimensional data and further including alignment between the pieces of three-dimensional data in the depth direction; and a generation unit configured to generate interpolation data of at least one piece of three-dimensional data among the pieces of three-dimensional data by using a result of the first planar alignment and a result of the first depth alignment.

Abstract: In an optical scanner 100, a vibration portion 101 includes first and third elements 3021 and 3023 that vibrate a light guide path 102 in a direction substantially perpendicular to an optical axis direction, and second and fourth elements 3022 and 3024 that vibrate the light guide path in a direction substantially perpendicular to a vibration direction thereof. A driving signal is applied to each of electrodes 3011 to 3014, each of which corresponds to one electrode of each of the first to fourth elements, and the other electrode 3015 is used as a common electrode having a floating potential. A driving signal generator 1007 generates a driving signal such that a median value of driving signals Vy1and Vy2 applied to the first and third elements and a median value of driving signals Vx1 and Vx2 applied to the second and fourth elements correspond to substantially the same value.