Abstract: A method and composition for disinfecting a contact lens is disclosed. The method includes treating a lens with an aqueous solution having reduced toxicity to the eye which contains an effective amount of a monoperphthalic acid compound in a concentration of less than about 0.5% by weight of the solution. The lens disinfecting solution is capable of disinfecting contact lenses without irritating the eye due to reduced toxicity of the composition.

Abstract: The present invention provides a universal decontamination formulation and method for detoxifying chemical warfare agents (CWA's) and biological warfare agents (BWA's) without producing any toxic by-products, as well as, decontaminating surfaces that have come into contact with these agents. The formulation includes a sorbent material or gel, a peroxide source, a peroxide activator, and a compound containing a mixture of KHSO5, KHSO4 and K2SO4. The formulation is self-decontaminating and once dried can easily be wiped from the surface being decontaminated. A method for decontaminating a surface exposed to chemical or biological agents is also disclosed.

Abstract: Methods are disclosed for sterilizing biological materials to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing biological materials containing one or more non-aqueous solvents with irradiation.

Abstract: A method of cleaning, disinfecting, and inhibiting mold and mildew growth on a non-porous hard surface is disclosed. The method utilizes a composition comprising an aliphatic alcohol, at least one organic ether, and optionally a secondary alcohol and is essentially free of conventional antibacterial agents including chlorine bleaches, quaternary ammonium compounds and phenolic compounds.

Abstract: A method for deodorizing shoes includes providing an ozone generator with a case of oblong shape; placing the ozone generator in the case in a shoe; energizing the ozone generator with electric power to generate an electric corona; and passing an oxygen containing gas through the electric corona so as to generate ozone, thereby deodorizing the shoe.

Abstract: Apparatus, systems and methods are disclosed for treating a biological fluid with light. A container of biological fluid is introduced into a fluid treatment chamber where it is contacted with light provided by one or more light sources in proximity to the fluid treatment chamber. A drawer for holding containers of biological fluid introduces the containers into the chamber. Containers for holding the biological fluid are marked by the apparatus to indicate the status of the treatment.

Abstract: A novel approach to fight bacterial growth on and attachment to medical devices/implants is described. This approach reduces the necessity of the painful and complicated replacement of the medical devices that frequently need to remain in the body for periods of time longer than is recommended using a traditionally sterilized device. Several methods are described to kill bacteria that have attached to the surface of medical devices. Long term use is then possible with those medical devices. Furthermore a medical device is described under this method that has a photosensitizing compound affixed to or near the device surface with means to periodically activate the compound by suitable illumination.

Abstract: The present invention relates to the use of a cleaning composition concentrate in particular for the mechanical cleaning of medical and/or surgical instruments and/or apparatuses and to a process for carrying out this cleaning.

Abstract: The present invention provides systems and methods for destroying pathogens (including bacteria and viruses) from delivery, postal or courier items such as letters, parcels, boxes, etc. In preferred aspects, the items to be treated are placed in a chamber which is then flooded with ozone gas at pressures above ambient atmospheric pressure. The exposure to pressurized ozone is carried out at a sufficiently high concentration, and for a sufficiently long duration such that the sterilizing ozone penetrates into the interior of the delivery, postal or courier item.

Abstract: A method for a parent to safely administer formula to a baby. The method includes the step of providing a pre-packaged, pre-sterilized, self-contained, disposable safety bottle by sterilizing a container; sterilizing formula; charging the sterilized container with the sterilized formula; sealing the container; and, removably mounting a nipple assembly on the container. The nipple assembly includes a base, a nipple, and a removable cover extending over the nipple. The method also includes the steps of delivering the safety bottle to the parent; removing the nipple assembly from the container; unsealing the container; remounting the nipple assembly on the container; removing the cover; administering the formula to the baby; and, discarding the safety bottle.

Abstract: A surface which carries a material which is infected with prions is cleaned with an alkaline cleaning solution to remove as much proteinaceous material as possible from the surface. The solution contains an alkaline cleaning agent which attacks prions remaining on the surface and which attacks prions removed from the surface during the cleaning step. After the cleaning step, the surface is exposed to a strong gaseous oxidant, preferably hydrogen peroxide vapor. The hydrogen peroxide or other strong oxidant attacks the prions, particularly the unclumped prion strands, deactivating the prions.

Abstract: A liquid fuel candle apparatus with a polymeric element impregnated with a fragrant volatile medium includes a wick with an ignitable end and an absorbent end, a receptacle for holding a quantity of fuel, with the absorbent end of the wick in contact with the fuel, a receptacle having at least a first wall which forms a perimeter, with the ignitable end of the wick extending through the receptacle, and a polymeric element impregnated with a volatile medium disposed within the receptacle perimeter, and in substantially continuous contact with the perimeter wall.

Abstract: This invention relates to a process for removing iron oxide deposit from a metal surface in contact with an aqueous system, in particular the metal surface of a boiler operating at high pressures. The process comprises adding an elevated dosage of an oxime to the aqueous system in an amount effective to partially or entirely remove iron oxide deposits from the metal surface.

Abstract: A chamber (10) is supplied with a pressurized cleaning agent of carbon dioxide and cosolvents from a first source (12) and an antimicrobial fluid, such as ethylene oxide or hydrogen peroxide from a second source (16). Chamber conditions are maintained in the sub-critical range for the carbon dioxide. The cleaning agent and antimicrobial fluid are recirculated through a separator (32) and a condenser (38) to filter contaminants from the mixture before returning the carbon dioxide, and optionally the antimicrobial fluid and other additives, to the chamber. Medical instruments or other articles within the chamber are cleaned by the cleaning agent and sterilized by the antimicrobial fluid in a single cycle, rendering them ready for reuse in a short period of time. The instruments may be cleaned and stored in hermetically sealable containers (82). The cleaning agent is rapidly evaporated from surfaces of the articles at the end of the cycle by reducing the pressure in the chamber.

Abstract: Biomedical devices that are to come into contact with living tissue, such as prosthetic and other implants for the human body and the containers used to store and transport them, are together cleaned of non-living, but biologically active organic materials, including endotoxins such as lipopolysaccharides, and assembled into a hermetically sealed package without recontamination. This is achieved by cleaning both the device and package components together in an apparatus, which includes a hermetically sealed chamber, in which they are contacted with atomic oxygen which biocleans them, by oxidizing the biologically active organic materials. The apparatus also includes means for manipulating the device and container and hermetically sealing the cleaned device into the cleaned container to form the package. A calibrated witness coupon visually indicates whether or not the device and container have received enough exposure to the atomic oxygen to have removed the organic materials from their surfaces.

Abstract: A method of washing, microbially decontaminating, and rinsing of a lumened device (B), such as an endoscope includes positioning the device in a chamber (12) of an automated processor (A). Spray nozzles (102, 104, 106, 108, 110) within the chamber sequentially spray washing, microbial decontaminant, and rinse fluids over the device. Fluid connection ports (150, 152, 154) connect with internal passages (187) of the device for delivering the fluids thereto. Leaking connectors (184) connect the automated processor connection ports with inlet ports (196) of the device and allow a portion of the washing, decontaminant, and rinse solutions to leak from each inlet port. A computer control system (80) controls leak testing, cleaning, decontamination, rinsing, and drying stages of a cycle, which are all carried out within the chamber, obviating the need for human contact with the device during processing.

Abstract: A device for killing pathogens that grow on the surface of the evaporator coil within a conventional air conditioner and in the drip pan of its evaporator. Utilizing ultraviolet radiation which is well-known to kill a wide range of pathogens, the device comprises at least one elongated ultraviolet light source. This source is positioned in such a way that its light strikes both the evaporator and the drip pan. Also this source is mounted transversely to the flow path of air passing through the evaporator.

Abstract: A sanitizing pouch secures to a product package and includes a sanitizing agent disposed therein. A delivery device includes an inlet thereto and an outlet therefrom. A probe attaches to the inlet of the delivery device. The probe is adapted to puncture the sanitizing pouch and the product package, whereby the puncturing of the sanitizing pouch by the probe releases the sanitizing agent over the probe thereby sanitizing the probe prior to the puncturing of the product package by the probe. After flowing over the probe, the sanitizing agent flows into the delivery device thereby sanitizing the delivery device. The delivery device draws product from the product package for delivery via its outlet.

Abstract: Apparatus and methods are disclosed for decontaminating mail. The preferred embodiment includes a sealable container of sufficient size to hold one or more pieces of mail. A chamber, in gaseous communication with the container, holds a quantity of oxidizer material, and a heater is used to raise the temperature of the oxidizer to form a disinfecting gas that permeates the mail. The oxidizer material is preferably a liquid such as chlorine dioxide or hydrogen peroxide. The apparatus may further include a timer so that the oxidizer is heated for a desired period of time, a pressure relief valve, and/or an indicator responsive to the pressure within the container when sealed.

Abstract: A composition and a method for decontaminating small diameter water lines for medical equipment which effectively dislodges and eliminates a biofilm and at the same time destroy the microorganism flora in the fresh water and in the dislodged biofilm. In addition the composition or method does not corrode water line materials, it is safe and non-toxic, it does not expose patients to the decontaminaiting chemicals or process, it does not leave significant residual chemicals in the water line, it does not require the use of sterile solutions and aseptic technique by dental personel, and it does not require mixing or dilution of chemicals prior to use.

Abstract: A flow-through rack assembly (14) includes porous hangers (44) which support items to be decontaminated within a decontamination chamber (12). A plurality of nozzles (16) spray a decontaminant fluid, such as peracetic acid, over the items. The rack assembly includes tubes (42) which convey a portion of the decontaminant fluid under pressure to internal channels (52) of the porous hangers. The fluid permeates the hanger surface, flowing over regions of the items which are in contact with the hangers. The rack assembly ensures decontamination of those regions which may be otherwise inaccessible to fluid sprayed from the nozzles.

Abstract: A system having a fluid source and a pasteurizer coupled with a disinfectant unit in flow communication with the fluid source for use in disinfecting dental or other water lines. The combination of pasteurizer and disinfectant unit is adapted to receive water from the fluid source. A fluid delivery unit is provided in flow communication with the pasteurizer and disinfectant unit combination. The disinfectant unit has a means for supplying hydrogen and oxygen and a means for generating hydrogen peroxide in flow communication with the means for supplying hydrogen and oxygen.

Abstract: A process is provided for disinfecting articles at temperatures below 5° C. with an aqueous alcoholic salt solution. The process provides a fast reduction of microorganisms at low temperatures with a wide degree of efficacy.

Abstract: The present invention provides methods for preparing tissue for incorporation into xenografts and bioprosthetic devices. The methods of the invention make use of supercritical fluids to remove infectious materials and chemical agents from tissues, as well as to permeate a tissue with a chemical agent (e.g. tanning, cross-linking, and bioactive agents).

Abstract: A method of determining the effectiveness of a sterilization cycle in a sterilization chamber by the use of an indicator containing DNA and a dye which can be bound thereto. The indicator containing DNA is placed in the sterilization chamber prior to the beginning of the sterilization cycle. When the DNA is subjected to heat and steam, the molecule is fragmented so that it is no longer capable of binding the dye. The DNA is withdrawn from the indicator after the sterilization cycle, contacted by a solution of the dye and, thereafter, dipped into wash water. If sufficient fragmentation has taken place, a substantial percentage of the dye will be washed off during the second dip. This is easily recognized by the operator and the efficacy of the cycle can be determined. On the other hand, if insufficient heat and steam has been applied, the remaining DNA will retain the dye and little or no change in color will be observed.

Abstract: Methods of inhibiting the growth of organisms in aqueous systems such as papermaking systems, cooling systems and process waters of various types, comprises adding to the aqueous system a hop acid. Compositions comprising hop acids and papermaking suspensions or slurries, and/or additives, such as paper making additives, are also provided.

Abstract: The present invention relates to a method of sterilizing and/or sanitizing a container using a sterilant vapor such as hydrogen peroxide. The sterilant vapor is discharged through a nozzle positioned in an opening of the container and the container is then purged of the discharged sterilant using a heated gas such as sterile air. The nozzle is preferably positioned no closer than 15 mm from the bottom surface or any internal surface of the container and within ⅙ to ⅚ of the height of the container. The nozzle has a diameter no greater than one-half of the diameter of the opening of the container. When containers made of non-heat set PET are used, the temperatures of the sterilant vapor and the purge gas are preferably no greater than 160° F.

Abstract: A method of producing Clean Water for Dental Delivery Units is described using colloidal silver to sanitize the water supply of dental water delivery units. The silver compound is generated by means of a proprietary process contained in a U.S. patent application. The Clean Water for Dental Delivery Units method is capable of delivering sterile water to dental patients from existing equipment with complete safety for patients and dental office staff.

Abstract: The use of polymeric corrosion inhibiting compositions incorporating heterocyclic groups is disclosed. The polymers form a protective barrier on metallic components to aqueous systems and remain substantive on metallic surfaces over a wide pH range. Moreover, the polymers are resistant to oxidizing biocides, and are substantially impervious to repeated or prolonged exposure to corrosive agents.

Abstract: A method monitors the concentration of an oxidative gas or vapor during a sterilization process in a sterilization chamber. A sensor formed of a chemical reactive with the oxidative gas or vapor coupled to a temperature probe is positioned inside of an enclosure containing an item to be sterilized. The enclosure is defined by a barrier impermeable to contaminating microorganisms and having at least a portion thereof which is permeable to the oxidative gas or vapor. The sensor is electrically connected through the barrier to contacts located exterior of the enclosure and connected to a control system thereby.

Abstract: The use of a new class of polymeric corrosion inhibiting compositions incorporating pendant heterocyclic groups is disclosed. The polymers form a protective barrier on metallic components to aqueous systems and remain substantive on metallic surfaces over a wide pH range. Moreover, the polymers are resistant to oxidizing biocides, and are substantially impervious to repeated or prolonged exposure to corrosive agents.

Abstract: An electrically activatable fumigating device, methods of using it, and methods of constructing the device, are disclosed. The device is adapted to be plugged into a wall outlet. It is provided with a resistance heater that is housed in a lower recess of a heating cup by crimping edges of the recess around the heater. The cup focuses the heat of the heater adjacent the bottom of the cup. A eutectic thermal cut-off operates as a primary means of energy cut-off. The resistance heater is also designed to fail after a specified heating period as a redundant means of cut-off.

Abstract: A device for detecting and providing an indication regarding one or more properties of a fluid retained in a bottle comprising a body member and a fluid property detecting substance, which can test for acidity, cork taint, or another fluid property, operably associated with the body member for detecting and providing an optical indication regarding one or more properties of the fluid retained in the bottle. The body member can have an open inner volume and the fluid property detecting substance can be disposed therein. A wall portion of the body member can comprise a semi-permeable barrier for allowing a one-way flow of fluid retained in the bottle into the open inner volume of the body member.

Abstract: A device for treating liquid medium has an ultrasound emitter located relative to a compartment of a container holding a liquid medium and a microbubble emitter located relative to the compartment. The ultrasound emitter emits high-frequency ultrasound between about 200 KHz and 10 MHz. The microbubble emitter emits bubbles with an average diameter of less than 1 mm.

Abstract: A process useful for disinfecting medical instruments is presented involving reacting a hydrogen peroxide donor with an N-acyl compound in an aqueous medium having a pH of 9 to 11 to form an acylated hydrogen peroxide preparation, reducing the pH of the acylated hydrogen peroxide preparation to pH 7 to 9; and contacting the acylated hydrogen peroxide preparation with a medical instrument. The process provides good antimicrobial activity with little corrosion. The process is effective against mycobacteria.

Abstract: There is disclosed a sterilizing fog, characterized by droplet size range, vapor density range, sterilant concentration range and sterilant concentration within the droplets. Specifically, there is disclosed a fog achieved by an apparatus combining pressure, temperature and acoustics to form a super-charged ozoneated water and an apparatus that creates small micro droplets which form a highly concentrated sterilizing fog. Specific sterilants used are ozone, chlorine and chlorous acid generating compositions such as sodium hypochlorite, or combinations thereof.

Abstract: Sterilization apparatus includes a monitoring system capable of continuously monitoring levels of a sterilant, such as hydrogen peroxide vapor. The monitoring system includes a sensor chamber joined in fluid communication with a sterilant supply conduit of the sterilization apparatus. A gas-detecting semiconductor sensing element, and associated temperature sensor, are provided within the sensor chamber to provide output signals corresponding to detected levels of sterilant. The sensor chamber isolates parametric influence, such as relative humidity, temperature and flow rate, to provide more accurate concentration level readings. A data collection circuit is operatively coupled to the sensors to provide an output corresponding to detected levels of sterilant within the apparatus.

Abstract: Disclosed are apparatus for delivery of a gas, e.g., carbon dioxide and/or chlorine dioxide, and methods of its use and manufacture. The apparatus includes an envelope, and a sachet within the envelope that contains reactant, which generates a gas in the presence of an initiating agent, e.g., water. The envelope allows release of the gas from the envelope. In another embodiment, the apparatus includes an envelope and a partition that separates two reactants within the envelope. The envelope allows an initiating agent into the envelope and release of the gas generated by the reactants in the presence of the initiating agent.

Abstract: The present invention relates to methods and forms of apparatus for sterilizing various objects with ozone. The contents of a container may be sterilized by attaching a lid with an ozone generator to the container and generating ozone. Clothing may be treated by attaching the clothing to an ozone generator with a housing in the shape of a clothes hanger and generating ozone. Alternatively, the ozone generator in the shape of a clothes hanger may be placed in a closet with clothing to be treated. The power supply for the ozone generator may be a portable power supply, or power may be supplied from an adapter from an electrical outlet. Shoes may be deodorized by placing an ozone generator with an oblong shape in the shoes and generating ozone.

Abstract: Disclosed herein are methods of sterilizing a device in a sterilizer, methods of sterilizing a device in an enclosure in a sterilizer, and enclosures for retaining a device capable of being sterilized in a sterilization process. The sterilization process comprises hydrogen peroxide vapor or gas. The sterilization load may include an enclosure, which can be a tray or a container. The tray or container comprises at least a volume of aluminum oxide. The ratio of the amount of hydrogen peroxide gas or vapor introduced into the sterilizer to the volume of aluminum oxide is at least 24 mg/cm3.

Abstract: The present invention involves a system and method of treating a porous material of a vehicle wherein the porous material has microorganisms. The method includes providing first and second antimicrobial solutions. The method further includes applying the first antimicrobial solution to the porous material and scrubbing the first antimicrobial solution and the porous material so that the first solution contacts the microorganisms. The method further includes applying the second antimicrobial solution heated at a predetermined temperature to the porous material after a predetermined time upon applying the first solution. The method further comprises removing the first and second antimicrobial solutions and the microorganisms from the porous material.

Abstract: A sterilization cassette and a sterilization method for sterilizing, storing, and dispensing dental instruments. The sterilization cassette includes a mounting bar and a locking bar for dental pliers of various types, a removable instrument tray, and a case with a front side which opens and hinges in two places, allowing the cassette to be arranged in horizontal and vertical configurations.

Abstract: Disclosed is a method of cleaning endoscopes within a container, wherein fluid flows from inside the container through the endoscope channels, predominantly in one direction, from the smaller-caliber end of an endoscope channel, or lumen, to the larger-caliber end. This method prevents the lodgment of particulate matter and human tissue in the smaller-caliber end of endoscope channels, and it allows fluid to flow through the entire length of all endoscope channels, to permit debris to exit the channels.

Abstract: A valve is provided which includes a valve body, a first valve member, and a second valve member. The valve body has a first flow passage formed therethrough and a second flow passage formed therein. The second flow passage has a smaller cross-sectional area than the first flow passage so that the valve can be used interchangeable between systems requiring different flow rates through the valve, and so that flow through the valve can be more accurately controlled than through the first flow passage alone.

Abstract: A method is disclosed for producing a printing ink decorated packaging material. The packaging material heat sealable outer coatings. One or both sides of the packaging material are subjected to corona discharge surface treatment to increase the surface tension. Printing is applied to the treated surface. The packaging material then passes the nip between heated rollers in order to reduce the surface energy of the outer plastic layers. Subsequently, a surface treatment of hydrogen peroxide is applied to the packaging material to sterilize the surface.

Abstract: A decontamination system including an absorptive/absorptive activated carbon felt pad saturated with a non-hazardous CWA decontamination solvent as nonspecific means of decontaminating equipment and open-wounds is provided. The entire system preferably includes an absorbent pad and decontamination fluid in a sealed, disposable plastic packet. The system is thus a simple and immediate means of personal decontamination. The decontamination fluid and the absorbent pads of the present invention are non-hazardous, nontoxic, and nonflammable. The system is thus safe, and able to readily meet with FDA approval. The system is small and easily corrected in a field pack or other means and can be safely disposed of after use. The same system is also useable at casualty receiving stations to decontaminate patients and/or equipment.

Abstract: A deodorizer includes (a) a deodorant which decomposes odor, (b) a tank containing the deodorant therein, (c) at least one nozzle which blows out the deodorant downwardly in the form of jet, (d) a conduit connecting the tank to the nozzle, (e) a pump which feeds the deodorant to the nozzle from the tank through the conduit, (f) a chamber which surrounds a distal end of the nozzle and is formed with an air inlet, and (g) a deodorizing tower which is in fluid communication with the chamber and which extends towards the deodorant contained in the tank.

Abstract: It is an object to establish a sterilization condition and means for decreasing the amount of a remaining sterilization agent as much as possible after sterilizing a rubbery sealing tool. In a sterilizing method using gaseous hydrogen peroxide, a filling rate of a sample in a sterilization bag for a normal type is set to 45% or more and a sterilization condition is set to a hydrogen peroxide treatment of 3 pulses and an aeration pulse of 20 pulses, thereby carrying out a sterilization treatment. Furthermore, it is preferable that a volume rate in a bag of an outer bag accommodating the sterilization bag should be set to 55 to 12%. By such setting, a survival ratio of 0/10 of a bacteria cell could be realized at first to fifth times of repetition of the sterilization treatment.

Abstract: A surface is sanitized by manufacturing a gaseous stream of ozone from oxygen having a purity of at least 90 vol. %, and injecting it directly into a stream of water having a pH of 6.5-7.5, feeding said aqueous solution of ozone into a tank which maintains a gaseous atmosphere comprising ozone over the solution, applying said aqueous solution of ozone from said tank onto a surface to be sanitized; and recovering water from said surface and recycling it to said source.

Abstract: An anticorrosive, penetration enhancing composition for cleaning decontaminating and rinsing includes electrochemically activated (ECA) water as the decontamination agent. The anticorrosive decontamination composition has, as the anticorrosive agent, a compound or mixture of compounds capable of inhibiting corrosion of various metals used in sterilization decontamination and rinsing systems and objects such as medical instruments. Preferred anticorrosive compounds include phosphates, azoles, and sulfates. Other additives, including wetting agents, are added to reduce the surface energy of the ECA water. This reduced surface energy permits the ECA water to penetrate into objects of complex design thus permitting complete decontamination of the treated object.