Abstract: Periodical sterilization is usually needed in the ultrapure water line provided in an ultrapure water-producing system or plant to kill some occasionally occurring viable cells of microorganisms in the ultrapure water as produced or being produced and thereby keep the ultrapure water under germ-free conditions. Now, it is discovered that an aqueous solution containing 1 to 100 ppm of hydrofluoric acid is effective to sterilize the ultrapure water line and is advantageous over the conventional sterilization agents such as aqueous hydrogen peroxide and sodium hypochlorite which were employed normally for the sterilization of the ultrapure water line.

Abstract: The invention relates to the use of 2,5-substituted 1,3,4-thiadiazoles of the formula ##STR1## in which R.sup.1 stands for straight-chain or branched halogenoalkyl,R.sup.2 stands for straight-chain or branched alkyl andn stands for the numbers 1 or 2,as microbicides for protecting industrial materials.

Abstract: Ophthalmic compositions, such as those used to care for contact lenses, methods of preserving such compositions, and methods for disinfecting contact lenses using such compositions are disclosed. The compositions may comprise an ophthalmically acceptable, liquid aqueous medium and, included therein, an effective preserving or disinfecting amount of certain oxygen-containing ionene polymers.

Abstract: A deodorizing and sterilizing apparatus includes a reaction chamber in which ozone generated by an ozone generator and chlorine dioxide generated by a chlorine dioxide generator react together to form chlorine trioxide and in which the chlorine trioxide is reacted with an article or air to be deodorized and sterilized, thereby deodorizing and sterilizing the article or air. The apparatus also includes an adsorbent for removing ozone and chlorine from a gas after reaction. With this construction, the apparatus is capable of performing an effective deodorizing and sterilizing process even at a low humidity level.

Abstract: Pressurized liquid is forced through the instrument simultaneous with submerging in a container of disinfectant or sterilization solution and also a gas may be introduced. The containers of the solutions receive the instrument which is mounted to be driven from one container to another, selectively by electric motors which are controlled through an electrical circuit that also operates pumps and valves in a pre-determined sequence of operations.

Abstract: A method of disinfecting a contact lens is disclosed and comprises placing the contact lens to be disinfected into a liquid electrolyte containing chlorine dioxide precursor, e.g., stabilized chlorine dioxide, and forming a disinfecting amount of chlorine dioxide in the liquid electrolyte by passing an electric current through the liquid electrolyte.

Abstract: Method for disinfecting a liquid medium or hard surface containing undesired halogen-sensitive micro-organisms by treatment with substituted N-halo derivatives of imidazolidin-4-ones having substituents at the 2 and 5 positions of the imidazolidin-4-one ring, including N-chloro, N-bromo, N,N'-dichloro, N,N'-dibromo, and N,N'-bromochloro derivatives of imidazolidin-4-ones having substituents selected from hydrogen, alkyl, alkoxy, hydroxy, phenyl, substituted phenyl, or spiro-substitution at the 2 and 5 positions on the ring. These N-halo compounds are stable, noncorrosive biocides which are resistant to direct sunlight, and are useful as disinfectants, sanitizers, and algae inhibitors.

Abstract: The present invention describes a novel method and apparatus for treating and/or disinfecting water and/or wastewater wherein the contact vessel may be sealed and may be under greater than atmospheric pressure having a detention time of no more than 5 minutes.

Abstract: A medical device is precision cleaned by being contacted with a choline-containing cleansing agent so as to remove pyrogens from the medical device.

Abstract: A composition able to absorb mercury vapor and to disinfect a surface. The composition hasa source of halogen; anda non-aqueous solvent of low vapor pressure for the source of halogen. The composition is of low vapor pressure.

Abstract: The present invention relates to methods and devices for the production of controlled quantities of chlorine dioxide at concentrations which are effective to function as a deodorant or a germicide. Aqueous chlorite compositions such as aqueous sodium chlorite are brought into contact at a controlled rate through capillary means, e.g. a wick with an absorbent pad containing acid or other reactant which will react with the chlorite and form chlorine dioxide.

Abstract: A method for sterilizing infectious waste includes placing the waste in a disposal apparatus which has an isolated volume for holding the waste. A dry granulated medium which has a disinfectant constituent is also placed within the isolated volume along with the waste. When the disposal apparatus is activated, an atomized mist is introduced into the volume and the waste, the medium, and the moisture in the mist are thoroughly blended together. The resulting destroyed waste is thoroughly moistened with the disinfectant solution which is formed by the mist and the disinfectant constituents of the medium. Then, the moistened, destroyed waste is heated to a predetermined temperature for a predetermined time to ensure efficacious sterilization of the waste.

Abstract: An improved infectious waste treatment system wherein infectious waste is fragmented and converted to a liquid or liquid/sludge form and then is chemically disinfected in a precisely controlled and timed batch process. The disinfection process takes place in an airtight sealed container to insure against release of pathogenic agents into the atmosphere. The process produces a non-toxic and non-infectious liquid or liquid/sludge waste residue which can be safely released into a sanitary sewer, landfilled or otherwise environmentally disposed.

Abstract: A method for cleaning cellular contamination in a flow cytometer comprising the sequential use of a strong oxidizing solution, particle-free neutral pH fluid and a weak acid.

Abstract: A method for cleaning, disinfecting and sterilizing hemodialysis apparatus consisting in mixing a basic composition comprising the chlorite ion with an acid composition comprising lactic acid in a ratio of the acid composition to the basic composition ranging from 1:2 to 4:4, feeding the mixture thus obtained and admixed with water into the hemodialysis apparatus, the ratio of the mixture to water being of about 1:34 and circulating the final solution in the apparatus wherein the mixture is diluted in water and the basic composition is reacted with the acid composition.

Abstract: Medical instruments, which may include brass, copper, aluminum, stainless steel, carbon steel, or plastic parts are sterilized or disinfected in an anti-microbial solution. The anti-microbial effect of a strong oxidizing agent, such as peracetic acid, is improved with a wetting agent. The solution further includes a triazole or other component for inhibiting the corrosion of copper and brass. Phosphates or other buffering agents adjust the oxidizing agent generally to a neutral pH for preventing the corrosion of steel. Molybdates or analogous compounds also buffer the pH and inhibit corrosion of aluminum by the oxidizing agent. The corrosion inhibiting is enhanced by the wetting agent. Optionally, a sequestering agent is provided for inhibiting hard water precipitation.

Abstract: A method of treating surfaces in order to eliminate microbial growth by adding an antibacterially effective amount of an organosilicon quaternary ammonium silatrane compound to the surface in order to destroy bacteria and fungi. The preferred organosilicon quaternary ammonium silatrane compound has the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4, each represent a hydrogen atom or a methyl, ethyl, propyl, or butyl radical.

Abstract: A water treatment device includes a buoyang body having a sleeve portion within which a holder containing a water treatment substance is housed. The sleeve portion and the holder each have holes therethrough to permit the flow of water therethrough. The sleeve portion and holder are arranged to regulate the flow of water through the holes such that quiescent conditions prevail inside the holder. This allows a rapidly dissolving water treatment substance such as calcium hypochlorite to be used.

Abstract: Described is particulate halogen-containing material, e.g., calcium hypochlorite, containing from about 0.1 to about 10 weight percent of colorant-treated particulate inorganic water soluble salt, e.g., sodium chloride. The colorant used with the sodium chloride salt is resistant to oxidation by the halogen specie in the material and is water dispersible. The amount of colorant used is from about 0.01 to about 5 weight percent, based on the inorganic salt. Preferred are the water dispersible phthalocyanine colorants.

Abstract: A sterilant mixture comprising 15 to 30 mole percent ethylene oxide and 70 to 85 mole percent 1,1-dichloro-,2,2,2-trifluoroethane and/or 1-chloro-1,2,2,2-tetrafluoroethane, and a sterilization method using same.

Abstract: A sterilant mixture comprising 14 to 25 mole percent ethylene oxide and 75 to 86 mole percent 1,1,2,2,2-pentafluoroethane, and a sterilization method using same.

Abstract: An antimicrobial composition for the treatment of non-oral and non-periodontal human disorders due to infectious microorganisms susceptible to antimicrobial treatment and wherein the composition is an aqueous or aqueous alcoholic solution of povidone iodine complex to which nascent oxygen is supplied and the resulting admixture being freshly applied to the said disorders.

Abstract: There is disclosed an antiseptic polish for covering highly touched surfaces which contain a solution comprising Povidone-Iodine of approximately 7.5 to 10 percent by volume dispersed in a liquid polish.

Abstract: There is disclosed a composition and process for disinfecting or essentially sterilizing blood fractions and components of blood. The composition is formed by adding a chlorine dioxide liberating compound with a weak organic acid and a heat activated saccharide.

Abstract: Volatile organic compounds including hydrocarbons, halogenated compounds and other hazardous and toxic chemicals are removed from air streams by contacting the air with a suspension of tiny aqueous droplets sized such that the droplets have an internal pressure significantly greater than atmospheric. The capacity of aqueous droplets to hold organic compounds and the rate of transfer of organic compounds from an air stream to the droplets increase rapidly as the droplet size decreases and the droplet internal pressure rises. After substantial transfer of volatile organic compounds from the air into the droplets is accomplished, the droplets are caused to grow and to coalesce and are separated from the air stream. The resulting liquid effluent is disposed of in a manner which prevents escape of contained contaminant compounds.

Abstract: An improved method of fumigating fresh plants on which pests are parasitic. The method comprises maintaining the fresh plants in a gaseous atmosphere composed of 10 to 50 mg/liter of methyl bromide, 0.01 to 10 mg/liter of hydrogen phosphide, and 1 to 50% by volume of carbon dioxide. The method can surely kill the pests on the plants without causing phytotoxicity.

Abstract: A method for disinfecting a contact lens is disclosed. This method comprises contacting a contact lens to be disinfected in a liquid medium with chlorine dioxide present in an amount effective to disinfect the contact lens to be disinfected.

Abstract: Dental and medical instruments and appliances are chemically sterilized by immersion in or subjection to a formulation or composition comprising as active antimicrobial agents a combination or admixture of an iodophor such as the povidone-iodine complex or a quaternary ammonium compound such as cetyl pyridinium chloride and a peroxide such as H.sub.2 O.sub.2, the antimicrobial action of the iodine derived from the iodophor being enhanced or potentiated by oxygen released from the peroxide. The invention is applicable also to the chemical sterilization of surgical sites. Procedure for making and using the sterilizing formulation or composition is described.

Abstract: An enzymatic sterilization system is disclosed which is effective against viruses and other organisms. Methods are disclosed to increase the rate of and reduce the cost for sterilization with this chemistry as compared to the prior art. Methods are disclosed to formulate a sterlizing chemistry which actively maintains a sterile environment over a defined period of time.

Abstract: Minimizing the leaching of iodine through packaging containing organic iodophor solution, by introducing into the packaging an amount of additional iodide which minimizes leaching of the iodine through the packaging and stabilizes the iodophor solution therein. The iodophor is preferably polyvinylpyrrolidone iodine.

Abstract: A method to preserve and sterilize biological tissues by exposing the tissue to microwave irradiation, thereby limiting tissue exposure to standard organic preservatives and retaining tissue pliability and other qualities that characterize natural, unpreserved tissue.

Abstract: The present invention relates to the art of agriculture. The method of sterilizing anthers of plants comprises treatment of the plants with a sterilizing agent in combination with a diluent during the period of the fifth and/or sixth stage of organogenesis. According to the invention, as the sterilizing agent use is made of derivatives of phosphoric acids of the general formula: ##STR1## wherein R is H, a C.sub.1 -C.sub.4 alkoxy, dimethylamine, wherein X is O, NH; B is H, a C.sub.1 -C.sub.4 alkyl, phenyl, D is H, CH.sub.3 ; A is a C.sub.1 -C.sub.4 alkyl, phenyl furyl; R' is OH, ONH.sub.4, OAlk(C.sub.1 -C.sub.4), phenyl; R.sup.2 is a C.sub.1 -C.sub.4 alkyl, NaNH.sub.4, NH.sub.3 Alk(C.sub.1 -C.sub.4), NH.sub.2 Alk.sub.2 (C.sub.1 -C.sub.4), or mixtures thereof. The method according to the present invention is useful in selection and seed production.

Abstract: The present invention is a germicidal solution for sanitizing the human epidermis without irritation. The solution is a homogenous blend of glycerol, sodium hypochlorite, inert ingredients, soft water, scented oil, and isopropyl alchol, having a pH of 9.8 to about 10.1. The solution may be applied to a towelette and sealed in a hermetically sealed pouch for later use.

Abstract: An improved process is disclosed for killing and inhibiting growth and reproduction (aftergrowth) of microorganisms comprising adding sufficient chloramine to kill the microorganisms without oxidizing high molecular weight organics, which are not easily assimilated by organisms that survive, into lower molecular weight ones, which are easily assimilated.

Abstract: Water soluble liquid quaternary ammonium polyhalides and quaternary ammonium polyhalides in water soluble admixture with surfactants, and their use in the control of biofouling in aqueous systems.

Abstract: Contact lenses can be sterilized effectively in a short time, by using a kit for contact lens sterilization which comprises an oxidizing agent for sterilizing contact lenses and a reducing agent for making nontoxic the oxidizing agent still remaining after sterilization and wherein the oxidizing agent and the reducing agent each have such a property and form that they do not substantially react with each other in the kit and that when they are placed in water substantially simultaneously, the major portion of the oxidizing agent dissolves in water more rapidly than the major portion of the reducing agent. Further, with this kit, the sterilized contact lenses can be made nontoxic without fail.

Abstract: A process for dry sterilization of medical or dental devices and materials in which these materials are subjected to an electrical discharge in a gaseous atmosphere to produce an active low temperature plasma for surface sterilization and treatment of the devices and materials.

Abstract: The use of stabilized chlorine dioxide or chlorine dioxide in aqueous solution as a composition to reduce or prevent plaque formation and treatment of oral diseases ecologically plaque dependent, such as gingivitis and periodontitis, is disclosed. Preferred concentrations are in the range of 0.005% to 0.2% and the chlorine dioxide may be in the form of a rinse, a wash, a soak or a dentifrice.

Abstract: It is well known that the transfusion of human blood and blood constituents, or the transplantation of corneas and sclerae, carries a substantial risk of transmission of AIDS and many other diseases. This disclosure describes a method of disinfecting certain blood constituents--particularly the red cells, platelets and proteins--or disinfecting corneal and scleral tissues, to make them safer for human transfusion or transplantation, while respectively maintaining their biologic or optical function. A sterilizing solution is prepared from, e.g., a commercially available disinfectant (such as LD.RTM. of Alcide Corporation) containing primarily lactic acid and sodium chlorite. Normal saline solution is used as diluent instead of distilled water. The blood constituent or cornea or sclera is exposed to the disinfectant for a time sufficient to inactivate or reduce the infectivity of disease agents.

Abstract: Novel azeotrope-like compositions comprising octafluorocyclobutane and ethylene oxide which are particularly useful as sterilizing gases.

Abstract: The present invention relates to the art of agriculture.A method of sterilizing anthers comprises treating the plants with a sterilizing agent in combination with a diluent during the period of the fifth and/or sixth stage of organogenesis. According to the present invention, as the sterilizing agent terpenoid compound are used having the following general formula: 1A ##STR1## or mixtures thereof. The method of the present invention is useful in selection and seed production.

Abstract: A method and apparatus for treating a material with gas or vapour, especially a fumigant, comprises a sealable enclosure device, a pump which may have an inlet for the agent and a heat reservoir, and a long flexible hose to allow the enclosure to be evacuated after treatment and the effluent discharged outside the premises where the material is treated.

Abstract: Aqueous cleaner compositions containing an alkali metal halogenite, for example, sodium chlorite; a perfume normally chemically incompatible with the halogenite in aqueous media, and a stabilizing amount of an anionic surfactant, the inclusion of which enhances the stability of the perfume-containing aqueous halogenite compositions.

Abstract: Anti-microbial compositions in the form of dry powders substantially instantly soluble in water, which exhibit stability for prolonged periods of time even at elevated temperatures of up to 130.degree. F., obtained by admixing an organic surfactant in which substantially all of the available oxidable groups have been replaced with fluorine to form a perfluoro surfactant, with a chlorinated isocyanuric acid. Preferably the anti-microbial compositions are obtained by admixing the following: trichloroisocyanuric acid, potassium hydroxide in an amount sufficient to neutralize the trichloroisocyanuric acid to its potassium salt, a fluorinated anionic surfactant, potassium monohydrogen phosphate and potassium chloride.

Abstract: Azeotrope-like compositions comprising ethylene oxide and dichlorotrifluoroethane isomers or mixtures thereof are novel constant boiling compositions which are useful as sterilizing gases.

Abstract: A process for controlling biomass and cleaning water injection wells and oil producing wells by injecting an oxidant into the pumped water injection stream. Chlorine dioxide or sodium chlorite, depending on the reactants present in the well, may be injected by means of a stinger, a spool or a coiled tube into the pumped water injection stream. Chlorine dioxide is generated at the site and may be generated by any one of several known processes. Hydrochloric acid or other proton donor stream, a water stream, and a stream containing sodium chlorate, sodium chlorite, and optional sodium chloride may be mixed at an elevated pressure to create chlorine dioxide. The elevated pressure of the chlorine dioxide stream is maintained at or boosted to a level greater than the pressure of the water injection or oil-producing well to aid in the injection of the chlorine dioxide stream either from generation to the well or through a booster pump mechanism to the well.

Abstract: A novel ester of carbamic acid useful in controlling the growth and proliferation of microorganisms. The novel compound is ##STR1## namely, 3-iodopropargyl ester of carbamic acid.

Abstract: It is well known that the transfusion of human blood and blood components carriers with it a substantial risk of transmission of AIDS and many other diseases. This disclosure describes a method of disinfecting red blood cells to make them safer for human transfusion, while maintaining their biologic activity. A sterilizing solution is prepared from, e.g., a commercially available disinfectant (LD.TM. Alcide Corporation) containing primarily lactic acid and sodium chlorite. Normal saline solution is used as diluent instead of distilled water. The red cells are exposed to the disinfectant for a time sufficient to inactivate or reduce the infectivity of disease agents. The normal-saline environment prevents or deters hemolysis. The blood cells are then washed with normal saline solution until the disinfectant concentration is insignificant. The blood is then safe for human transfusion.

Abstract: A method of inhibiting the corrosion of the metal surfaces of beer pasteurizing units in contact with halogenated water vapor which comprise treating these halogenated waters with at least 1/4 ppm sulfamic acid for each ppm of halogen present in these waters.

Abstract: Dental and medical instruments and appliances are chemically sterilized by immersion in or subjection to a formulation or composition comprising as active antimicrobial agents a combination or admixture of an iodophor such as the povidone-iodine complex or a quaternary ammonium compound such as cetyl pyridinium chloride and a peroxide such as H.sub.2 O.sub.2, the antimicrobial action of the iodine derived from the iodophor being enhanced or potentiated by oxygen released from the peroxide. The invention is applicable also to the chemical sterilization of surgical sites. Procedure for making and using the sterilizing formulation or composition is described.