Read By Automated Means Patents (Class 422/403)
  • Patent number: 11327069
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: May 10, 2022
    Assignee: CA CASYSO GMBH
    Inventors: Cory Lee McCluskey, Robert S. Hillman, Michael Gorin, Hubert Martin Schwaiger
  • Patent number: 11291739
    Abstract: Systems and methods for sterilizing an enclosed space using ozone are disclosed herein. Various embodiments of the devices and methods also provide for accelerated degradation of the ozone upon sterilization. The methods can include identifying enclosed spaces, sterilizing enclosed spaces through ozone generation, generating reports and transmitting the reports. The sterilization unit disclosed herein can sterilize a plurality of enclosed spaces, such as a fleet of medical response vehicles.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: April 5, 2022
    Assignee: Gene Therapy Systems, Inc.
    Inventors: Steven J. Jurak, Anthony M. Sorge, Sr.
  • Patent number: 11293844
    Abstract: A tissue processing apparatus for processing biological tissue. The tissue processing apparatus includes: an extraction device configured to, when connected to a reagent receptacle, take reagent out from the reagent receptacle for use by the tissue processing apparatus; a tag reader configured to read information from a machine-readable tag.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: April 5, 2022
    Assignee: SHANDON DIAGNOSTICS LIMITED
    Inventors: Daniel Peter Robinson, Michael James Forshaw, David John Chan, Mark Baker, David McNulty, Marc Neill Murphy
  • Patent number: 11224362
    Abstract: Subject matter disclosed herein relates to monitoring and/or controlling blood glucose levels in patients. In particular, times for obtaining metered blood glucose samples of a patient may be altered based, at least in part, on a blood glucose level of said patient observed from a blood glucose sensor.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: January 18, 2022
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Rebecca K. Gottlieb, Meena Ramachandran
  • Patent number: 11000614
    Abstract: A sterilization system includes a communication hub that is configured to transfer information between devices of the system such as a sterilizing cabinet, biological indicator analyzer, and a server in order to allow a user to track a medical device throughout a sterilization process. The server may provide data to the sterilizing cabinet during a sterilization process that may be used to verify that the medical device is compatible with the sterilizing cabinet, and to automatically select a compatible sterilization cycle to perform on the medical device. Automatic selection of sterilization cycles and confirmation of compatibility reduces the possibility for user error, which could result in contaminated medical devices being placed back into service. Automatic selection of sterilization cycles also allows users to more efficiently configure and perform sterilization cycles while being confident that the medical device will be sterile upon completion.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: May 11, 2021
    Assignee: ASP GLOBAL MANUFACTURING GMBH
    Inventors: Philippe K. Dang, Venkata Danam, Jeremy M. Yarwood, Yaeer Lev, Brian J. Thompson, Amy K. Smith, Sora Rhee
  • Patent number: 10668180
    Abstract: A sterilizing cabinet performs a method of processing a medical device, such as a used medical device or an otherwise non-sterile medical device. The method includes receiving input from a user selecting a sterilization cycle from a plurality of available sterilization cycles. The sterilizing cabinet identifies a biological indicator associated with the selected sterilization cycle. The sterilizing cabinet prompts the user via a touch screen display to place the medical device and the biological indicator into a sterilization chamber of a sterilizing cabinet. The sterilizing cabinet performs load conditioning on the medical device in the sterilization chamber. The sterilizing cabinet then performs the selected sterilization cycle on the medical device in the sterilization chamber after completing the act of load conditioning.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: June 2, 2020
    Assignee: ASP GLOBAL MANUFACTURING GMBH
    Inventors: Brian J. Thompson, Jacob S. Childs, Chunhui Xie, Marco A. Mangiaterra, Darius D. Eghbal, Margaret D. Shaffer, Jeremy M. Yarwood, Benjamin M. Fryer
  • Patent number: 10632220
    Abstract: A biological indicator with variable resistance may be controlled by moving a cap or housing of the biological indicator to cause the size of vents that allow flow of sterilant through the housing to decrease or increase in effective size. An indicator window may show a user the current resistance of the biological indicator, and may also show a readable indicator that may be captured by a scanner to allow a sterilizing cabinet to identify the current resistance. When the level of resistance shown by the readable indicator is not compatible with a sterilization cycle selected by a user, the procedure may be delayed and a notification provided to the user that a problem exists. The readable indicator may be a passive tag with a memory that allows information to be read and written, so that the biological indicator may carry data from one device to another.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: April 28, 2020
    Assignee: ASP GLOBAL MANUFACTURING GMBH
    Inventors: Yan Fang, Griffith E. Altmann, Behnam Amin, Jeremy Yarwood, Lawrence Y. Mok
  • Patent number: 10613068
    Abstract: Disclosed are polymer nanofiber sensors for detecting gas, which generates visible color change although a specific gas having a concentration of less than 1 ppm is exposed to the sensor in a short time, in which it is impossible to detect the gas using existing colorimetric sensors, through securing high surface area and porosity, and a method of the same.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: April 7, 2020
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Il-Doo Kim, Jun Hwe Cha, Won-Tae Koo
  • Patent number: 10433774
    Abstract: Subject matter disclosed herein relates to monitoring and/or controlling blood glucose levels in patients. In particular, times for obtaining metered blood glucose samples of a patient may be altered based, at least in part, on a blood glucose level of said patient observed from a blood glucose sensor.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: October 8, 2019
    Assignee: Medtronic Minimed, Inc.
    Inventors: Rebecca K. Gottlieb, Meena Ramachandran
  • Patent number: 10360368
    Abstract: Systems, devices, and methods are provided for the control of interfacing between applications that facilitate the monitoring of diabetes running on a mobile device, including the authentication of a third party user interface application by a sensor interface application. Control of the display of current analyte levels and critical events is also provided.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: July 23, 2019
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Glenn Berman, Nathan Crouther, Michael R. Love, Mark Sloan
  • Patent number: 10113987
    Abstract: An analyte meter to detect an analyte concentration level in a bio-fluid sample may be cleaned and disinfected with a cleaning liquid without harming electrical and internal meter components. In some embodiments, the analyte meter is washable and immersable and may include a sealed sensor connector, sealed battery connector, and possibly a sealed USB connector that may be subjected to a cleaning liquid without the liquid entering an internal chamber of the analyte meter and contacting internal electronic components. In some embodiments, a sealed display screen and sealed keypad are provided such that liquids are prevented from entering the internal chamber. Manufacturing methods and systems utilizing the analyte sensors are provided, as are numerous other aspects.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: October 30, 2018
    Assignee: ASCENSIA DIABETES CARE HOLDINGS AG
    Inventors: Eugene Prais, David Huang, James A. Johnson, Igor Gofman, Jun Chen
  • Patent number: 10048262
    Abstract: An immunochromatographic method for detecting a specific substance contained in milk, which comprises (1) the step of contacting the milk with a test strip having a first part retaining a labeled first antibody directed to the specific substance or the specific substance that is labeled, a second part disposed downstream from the first part, on which a second antibody directed to the specific substance is immobilized, and a third part disposed upstream from the first part or the second part and having voids enabling removal of milk fat globules contained in the milk, at the third part or a further upstream part, and (2) the step of flowing the milk up to the second part or a further downstream part to obtain a detectable signal of the label at the second part or a further downstream part.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: August 14, 2018
    Assignee: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Koji Maehana, Kenji Matsuyama
  • Patent number: 9970923
    Abstract: An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: May 15, 2018
    Assignee: Church & Dwight Co., Inc.
    Inventors: Andy Sturman, Benedict Zin, Albert Nazareth, Henry Bell
  • Patent number: 9551699
    Abstract: In some examples, a device applies an electrical potential difference across a blood sample. The device measures an electrical signal that passes through the blood sample over a duration of time to obtain a plurality of measurements representing a measurement function of time. An accumulative property of the measurement function may be determined such that the accumulative property correlates to a blood coagulation characteristic.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: January 24, 2017
    Assignee: Micropoint Bioscience, Inc.
    Inventors: Pingyi Yan, Haitao Huang, Shenyu Wang, Huihui Lu
  • Patent number: 9535059
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: January 3, 2017
    Assignee: California Institute of Technology
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Publication number: 20150147245
    Abstract: The present invention relates to an examination element that includes an antenna; a hygroscopic portion that absorbs a specimen; a reagent portion that reacts with the specimen; and a chip including a semiconductor device capable of wireless communication and a photo sensor that detects a change in a color of the reagent portion. A change in the reagent portion is detected by the photo sensor, the detected data is stored in the semiconductor device capable of wireless communication, and the data is transmitted to an external database.
    Type: Application
    Filed: February 5, 2015
    Publication date: May 28, 2015
    Inventor: Kunio HOSOYA
  • Patent number: 9028756
    Abstract: A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container (150) and sampling it in a first container (153), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container (154) and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: May 12, 2015
    Assignee: Sysmex Corporation
    Inventors: Norimasa Yamamoto, Takashi Yamato, Naohiko Matsuo, Satoshi Iguchi
  • Publication number: 20150125362
    Abstract: Judgment as to whether an analyte is present is performed before a washing step in which a washing liquid for washing a test area and the vicinity of the test area is supplied to a test strip. If the analyte is detected, the judgment ends, but if the analyte is not detected, judgment is performed again after the test area and the vicinity of the test area are washed.
    Type: Application
    Filed: January 8, 2015
    Publication date: May 7, 2015
    Applicant: FUJIFILM Corporation
    Inventors: Koji WATANABE, Tomonori NISHIO
  • Publication number: 20150099306
    Abstract: A reading device for reading and analyzing a test cassette having an identification code includes a reading unit, used for reading the identification code marked by the test cassette and carrying out interpretation on a plurality of test lines of the test cassette; an operating unit, used for operating the reading device; a processing unit, used for interpreting a test result with the identification code and the test lines; and a display unit, used for displaying the test result of the test cassette.
    Type: Application
    Filed: April 7, 2014
    Publication date: April 9, 2015
    Inventor: HUI-CHI KU
  • Publication number: 20150098873
    Abstract: A test cassette applicable to an optical reading device capable of reading identification codes includes a test sheet with a supporting layer and a reactive reagent layer; a case for retaining the test sheet; and an identification code situated on a surface of the case for recording a test item and a test standard value of the test cassette.
    Type: Application
    Filed: April 7, 2014
    Publication date: April 9, 2015
    Inventor: HUI-CHI KU
  • Patent number: 8986611
    Abstract: A sample analysis apparatus configured to automatically press a start button upon installation of a sample tube is provided. The sample analysis apparatus includes: a body of the sample analysis apparatus; a door housing which may be provided in an opened state or a closed state, and configured to be coupled to the body of the sample analysis apparatus by a hinge; a tube accommodating unit included in the door housing and configured to accommodate the sample tube; a start button included in the body of the sample analysis apparatus and configured to start analysis of the sample; and an operating member positioned at a first position which is distant from the start button the sample tube is not installed in the tube accommodating unit, and a second position which is configured to operate the start button when a sample tube is installed and the door housing is closed.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: March 24, 2015
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Yong Koo Lee, Tae Soo Kim, In Duk Hwang, Seock Woo Jang, Chul Ho Yun
  • Patent number: 8986624
    Abstract: A measurement device includes a housing and at least one display integrated in the housing. The housing includes a recess adapted for insertion of a cartridge into the housing to deliver a sample to be measured to the device. The recess has an opening at the front of the housing and a first part of the housing for insertion of the cartridge protrudes in a direction enclosing an angle with a second part of the housing.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: March 24, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Albert Hendrik Jan Immink, Petrus Johannes Wilhelmus Van Lankvelt, Tom Philippe Jean Jacques Delaey
  • Publication number: 20150082227
    Abstract: Various systems and methods of operating an analyte measurement device is provided. The device has a display, user interface, processor, memory and user interface buttons. In one example, one of the methods can be achieved by measuring an analyte with the analyte measurement device; displaying a value representative of the analyte; prompting a user to activate a test reminder; and activating the test reminder to remind a user to conduct a test measurement at a different time. Other methods and systems are also described and illustrated.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 19, 2015
    Inventors: Antony SMITH, Allan FAULKNER
  • Patent number: 8968676
    Abstract: A hand-held device for measuring an analyte concentration in a sample of a body liquid includes a display means for displaying measured values; a measured-value storage for storing measured values; a measuring unit for generating measured values through measurements of the analyte concentration; a clock; a control unit for generating measured value datasets, each containing a measured value supplied by the measuring unit as well as the date and hour of the measurement by which the measured value was obtained, and for writing them into the measured-value storage; and operating elements that can be actuated by the user to set the clock, in which case the control unit will generate a time-correction dataset indicating the amount and direction of the setting effected. The control unit writes time-correction datasets into the measured-value storage so that a chronologically ordered sequence is generated containing time-correction datasets and measured value datasets.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: March 3, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Ulrich Porsch, Bernd Steiger, Gertrud Albrecht, Uwe Wittmann
  • Patent number: 8951483
    Abstract: The present invention relates to an examination element that includes an antenna; a hygroscopic portion that absorbs a specimen; a reagent portion that, reacts with the specimen; and a chip including a semiconductor device capable of wireless communication and a photo sensor that detects a change in a color of the reagent portion. A change in the reagent portion is detected by the photo sensor, the detected data is stored in the semiconductor device capable of wireless communication, and the data is transmitted to an external database.
    Type: Grant
    Filed: September 12, 2007
    Date of Patent: February 10, 2015
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventor: Kunio Hosoya
  • Patent number: 8951474
    Abstract: The present invention provides an apparatus for analyzing particles in a solution including a unit configured to place a flow cell having a flow path for flowing a sample solution containing the particles; a unit configured to illuminate the sample solution flowing through the flow path of the flow cell; a photodetector that detects a scattered light and/or fluorescence generated from the particles in the sample solution; and a unit configured to analyze the particles based on their signal intensities detected by the photodetector, wherein the flow cell has the flow path formed in a substrate, a reflection plane is formed on the side surface of the flow path, the reflection plane leads the lights generated in the flow path of the flow cell and advancing in the substrate in-plane direction to a specified region of the surface of the flow cell, and the photodetector detects the light exiting from the specified region to the outside.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: February 10, 2015
    Assignee: On-Chip Biotechnologies Co., Ltd.
    Inventor: Kazuo Takeda
  • Patent number: 8945939
    Abstract: The invention is directed towards methods and compositions for identifying the amount of hydrofluoric acid in a buffered oxide etching composition. In buffered oxide etching compositions it is very difficult to measure the amount of hydrofluoric acid because it has varying equilibriums and it is toxic so it hard to handle and sample. When used to manufacture microchips however, incorrect amounts of hydrofluoric acid will ruin those chips. The invention utilizes a unique method of spectrographically measuring the hydrofluoric acid when in contact with added chromogenic agents to obtain exact measurements that are accurate, immediate, and safe.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: February 3, 2015
    Assignee: Ecolab USA Inc.
    Inventors: Amy M. Tseng, Brian V. Jenkins, Robert Mack
  • Patent number: 8940246
    Abstract: A system for diagnostic testing may include a meter for performing a diagnostic test on a sample applied to a test media, the meter having a housing and an interface for receiving a signal representing coding information, and a container configured to contain test media compatible with the meter, the container having a coding element associated therewith. Additionally, the system may provide a mechanism for removing the meter from an interconnected test container and reattaching it to a new container using on-container coding methods that can recalibrate the meter for the new container of test strips.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: January 27, 2015
    Assignee: Nipro Diagnostics, Inc.
    Inventors: Gary T. Neel, Brent E. Modzelewski, George R. Rounds, Carlos Oti, Allan Javier Caban, Jeffrey Akins
  • Patent number: 8940538
    Abstract: The present invention relates to an apparatus for quantifying the binding and dissociation kinetics of molecular interactions of small molecular bio materials with high sensitivity almost without the influence of a change in the reflective index resulting from a buffer solution by making polarized incident light incident on the binding layer of a bio material, formed in a thin dielectric film, so that the polarized incident light satisfies a p-wave non-reflecting condition and a quantifying method using the same.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: January 27, 2015
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Hyun Mo Cho, Gal Won Che, Yong Jai Cho
  • Patent number: 8936754
    Abstract: There is provided a high-accuracy automatic analysis device achieving both of measurement in a wide concentration range and high sensitivity at a low concentration. The signals of a plurality of wavelengths ?1 to ?12 where the sensitivity of light absorption caused by fine particles is high from a light source 40 are converted to absorbances by a spectroscopic optical system (detector) 41. The absorbances are converted to a secondary parameter from in which a noise component is cancelled by using a previously-defined conversion table 54, so that a concentration of a measured material (predetermined component) is calculated by an operation unit (calculating means) 53 based on the secondary parameter. Thus, analysis being resistant to the noise even at the low concentration can be achieved in a range up to a high concentration.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: January 20, 2015
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Isao Yamazaki, Hiroaki Ishizawa, Sakuichiro Adachi
  • Patent number: 8932874
    Abstract: The invention is directed towards methods and compositions for identifying the amount of ammonium acid in a buffered oxide etching composition. In buffered oxide etching compositions it is very difficult to measure the amount of ammonium acid because it has varying equilibriums and it is toxic so it hard to handle and sample. When used to manufacture microchips however, incorrect amounts of ammonium acid will ruin those chips. The invention utilizes a unique method of spectrographically measuring the ammonium acid when in contact with added chromogenic agents to obtain exact measurements that are accurate, immediate, and safe.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: January 13, 2015
    Assignee: Nalco Company
    Inventors: Amy M. Tseng, Brian V. Jenkins, Robert M. Mack
  • Patent number: 8932537
    Abstract: A portable tester to detect one or more analytes from explosives, drugs, or household chemicals, comprising: a plurality of chemical disposable, detachable reagent reservoirs storing reagents to induce a series of color reactions, wherein developed color depends on sequences of applied reagents to respective pads on a support base, reaction times and temperatures on said pad to create one or more color bar codes for a specific analyte. The tester comprises a piezoelectric dispenser coupled to each respective reservoir to dispense a mist of reagent onto respective test pads to increase sensitivity and reduce reaction heat and time; wherein piezoelectric dispenser is processor controlled to control dispensing time and volume in each step.
    Type: Grant
    Filed: April 28, 2009
    Date of Patent: January 13, 2015
    Assignee: Chemspectra, Inc.
    Inventors: Jeffrey Haas, Douglas Haas
  • Publication number: 20150011020
    Abstract: A system and method for detecting harmful substances within a consumable sample comprising: receiving a consumable sample at a first chamber of a test container; transforming the consumable sample into a homogenized sample upon processing of the consumable sample; delivering the homogenized sample to a second chamber of the test container, wherein the second chamber is configured to receive the homogenized sample comprises an outlet port; mixing the homogenized sample with a process reagent within the second chamber, thereby producing a dispersion; transmitting a volume of the dispersion to an analysis chamber, of the test container, configured to position a detection substrate proximal the port of the second chamber and comprising a detection window that enables detection of presence of the allergen; and detecting presence of the allergen within the consumable sample by way of an optical sensor configured to detect signals indicative of the allergen through the detection window.
    Type: Application
    Filed: September 26, 2014
    Publication date: January 8, 2015
    Inventors: Scott Sundvor, Steven Portela, Jonathan Ward, John Walton, Jonathan William Kiel, Jeffrey Mekler, Shireen Yates, Jacob Mooney
  • Publication number: 20150010441
    Abstract: A handheld, readily portable, electronic pregnancy test device including a Central Processing Unit in operational communication with a human Chorionic Gonadotropin hormone sensor able to detect a level of human Chorionic Gonadotropin in a blood sample disposed upon a test strip, said test strip loaded into the device through a test strip portal, wherein a pregnancy is verifiable and human Chorionic Gonadotropin doubling times are immediately calcuble whereby the health of the pregnancy is determinable absent direct medical assistance.
    Type: Application
    Filed: July 2, 2013
    Publication date: January 8, 2015
    Inventor: Elana M. Kahn
  • Patent number: 8916109
    Abstract: A diagnosis support method comprising: obtaining first blood glucose level information at a first time point and/or second blood glucose level information at a second time point which is later, by a predetermined period, than the first time point; placing a collection member, which is configured to collect a tissue fluid, on the skin of the subject for the predetermined period from the first time point to the second time point; obtaining glucose information about an amount of glucose contained in the tissue fluid collected by the collection member; and generating diagnosis support information for supporting a diagnosis of presence or absence of hypoglycemia in the subject, based on the first blood glucose level information and/or the second blood glucose level information and the glucose information. A diagnosis support system and a diagnosis support apparatus are also disclosed.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: December 23, 2014
    Assignee: Sysmex Corporation
    Inventors: Seiki Okada, Toshiyuki Sato
  • Patent number: 8900514
    Abstract: The invention discloses a blood analyzing device (100) comprising a holder (110) arranged for carrying a container (10) having a cuvette (20) containing a blood sample (30). The container (10) is positioned in the holder (110) so that a longitudinal axis (60) of the cuvette (20) is angled relative a horizontal axis (70). A light source (120) provides light (40) into the sample (30) and a detector (130) detects the output light (50) from a sub-portion of the blood sample (30). Kinetic information indicative of the change in hemoglobin concentration in a measuring volume (32, 34) is determined by a Hb processor (145) from the detected output light (50). An ESR processor (140) determines the erythrocyte sedimentation rate of the sample (30) based on the kinetic information.
    Type: Grant
    Filed: September 1, 2008
    Date of Patent: December 2, 2014
    Inventor: Tommy Forsell
  • Patent number: 8883491
    Abstract: The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: November 11, 2014
    Assignee: Nexcelom Bioscience LLC
    Inventors: Bo Lin, Peter Y. Li, Jean Qiu, Timothy Smith, Todd Sobolewski, Alnoor Pirani
  • Patent number: 8883086
    Abstract: Disclosed herein are an apparatus and method for measuring biomedical data and a measurement strip. The apparatus includes a plurality of detection units arranged within a strip reception area on a plane and spaced apart from each other, a measurement type determination unit for determining whether reactive portions are present in areas of the measurement strip corresponding to the plurality of detection units based on detection results obtained by the detection units and determining a type of measurement based on results of the determination, a biomedical data measurement unit for activating part or all of the detection units according to the type of measurement determined by the measurement type determination unit, and measuring the biomedical data using the activated detection units, and an output unit for outputting the measured biomedical data to an outside.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: November 11, 2014
    Assignee: Infopia Co., Ltd.
    Inventors: Byeong-Woo Bae, Sung-Dong Lee, Byung-Hoon Kho, Ji-Eon Ryu, Jin-Kyeong Kim, Hyou-Arm Joung
  • Patent number: 8871155
    Abstract: A device for detecting the presence or amount of an analyte in a fluid sample and method thereof, comprises a sample collector and a receiving cup for receiving and holding the sample collector within the receiving cup. The sample collector contains a compressible absorbent member for collecting the fluid sample, and has a first position and a second, locked position within the receiving cup. The absorbent member is uncompressed in the first position and is compressed in the second, locked position. The sample collector or the receiving cup has at least one test element having reagents for detecting the presence or amount of the analyte in the fluid sample.
    Type: Grant
    Filed: November 13, 2006
    Date of Patent: October 28, 2014
    Assignee: Alere Switzerland GmbH
    Inventors: Yuzhang Wu, Yun Ling, Jielin Dai
  • Publication number: 20140315229
    Abstract: This invention relates to a testing system arrangement for assessing the level of a biochemical marker, comprising a disposable device (2) with a sample inlet (4) and a at least one visible detection compartment (5A, 5B), for detection of said bio-chemical marker, a mobile unit (8) including a digital camera arranged to capture a digital picture (60) of said at least one visible detection compartment (5A, 5B), software run on a processor for analysing said picture (60) to assess said level and means arranged to present the result (70) of said assessment in a display (8A) of or connected to, said mobile unit (8), wherein said disposable device (2) is arranged with at least one reference surface (12) having a predetermined colour setting that is known to said software to enable exact assessment of the colour within said detection compartment (5A, 5B) by the use of said reference surface (12) within said digital picture as a basis reference.
    Type: Application
    Filed: November 22, 2012
    Publication date: October 23, 2014
    Applicant: Calmark Sweden AB
    Inventors: Mathias Karlsson, Sofia Hiort Af Ornaes, Hjalmar Didrikson
  • Patent number: 8865091
    Abstract: Sample processing devices that include transmissive layers and control layers to reduce or eliminate cross-talk between process chambers in the processing device are disclosed. The transmissive layers may transmit significant portions of signal light and/or interrogation light while the control layers block significant portions of signal light and/or interrogation light. Methods of manufacturing processing devices that include transmissive layers and control layers are also disclosed. The methods may involve continuous forming processes including co-extrusion of materials to form the transmissive layer and control layer in a processing device, followed by formation of the process chambers in the control layer. Alternatively, the methods may involve extrusion of materials for the control layer, followed by formation of process chambers in the control layer.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: October 21, 2014
    Assignee: 3M Innovative Properties Company
    Inventors: Joel R. Dufresne, Bryan C. Feisel, Theresa J. Gerten, Brent R. Hansen, David D. Nguyen
  • Publication number: 20140273256
    Abstract: Persons with diabetes often carry a handheld glucose meter as well as a portable computing device, such as a mobile phone. Given the close proximity of these two devices, the portable computing device can serve as a data collector for the glucose measures taken by the glucose meter. Improved techniques are set forth for transferring glucose measures automatically and seamlessly to the patient's portable computing device, including displaying a value for the glucose measure along with an identifier for the portable computing device on a display of the glucose meter during the data exchange with the portable computing device.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 18, 2014
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Carol J. Batman, Stacia Davis, David B. Markisohn, Erin K. McKinney, Mark G. Mears, Amy S. Stanley, Benjamin E. Strickrod
  • Patent number: 8828330
    Abstract: The present disclosure provides a sensor port configured to receive a plurality of analyte sensors having different sizes, shapes and/or electrode configurations. Also provided are analyte meters, analyte monitoring devices and/or systems and drug delivery devices and/or systems utilizing the disclosed sensor ports.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: September 9, 2014
    Assignee: Abbott Diabetes Care Inc.
    Inventors: John R. Galasso, Matthew Simmons, Gary Ashley Stafford, Cherie Bulala, Christopher Myles, Philip Justus Wunderle, III, Bonita Song, Richard G. Ries, Morvarid G. Shafie
  • Patent number: 8828730
    Abstract: Disclosed is a method for measuring thrombin generation in a whole blood sample. The whole blood sample may be applied forthwith, without prior processing. The blood cells and blood plasma in the whole blood sample are separated by (lateral) flow migration. Also disclosed is an assembly of a sample support and a device dedicated to measure thrombin generation in a whole blood sample. Advantageously, the sample support comprises a separator medium allowing separation of whole blood into blood cells and blood plasma by means of (lateral) flow migration.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: September 9, 2014
    Assignee: Synapse B.V.
    Inventors: Hendrik Coenraad Hemker, Rafael Jesus Apitz-Castro, Sebastiaan Nijhuis
  • Publication number: 20140219885
    Abstract: Techniques for fast and accurate measuring test strip intensities are disclosed herein. A method for measuring a test strip intensity comprising steps of obtaining an image of a sample line in a test strip and a plurality of reference lines, wherein the reference lines have known intensities; determining grayscale values of the sample line and the reference lines from the image; constructing a standard curve based on the grayscale values versus the known intensities of the reference lines; and determining the intensity of the sample line by fitting the grayscale value of the sample line on the standard curve.
    Type: Application
    Filed: January 30, 2014
    Publication date: August 7, 2014
    Inventors: Ge Cong, Lijun Wu, Richard Cong
  • Patent number: 8784736
    Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: July 22, 2014
    Assignee: Keck Graduate Institute
    Inventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
  • Publication number: 20140154789
    Abstract: A testing apparatus for performing an assay, the testing apparatus comprising: a receptacle (2) containing a reagent, the reagent being reactive to an applied test sample by developing a colour or pattern variation; a portable device (1), e.g. a mobile phone or a laptop, comprising a processor and an image capture device (3), wherein the processor is configured to process data captured by the image capture device and output a test result for the applied test sample.
    Type: Application
    Filed: March 30, 2012
    Publication date: June 5, 2014
    Inventors: Neil Polwart, Graham Tyrie, Anthony Peter Ashbrook
  • Patent number: 8741219
    Abstract: A sample processing system comprising: a transporting apparatus for transporting a sample; a plurality of sample processing apparatuses, arranged along a direction in which the sample is transported by the transporting apparatus, for processing the sample transported by the transporting apparatus; a base on which at least one of the sample processing apparatuses is placed; and a movement restricting section for restricting, on the base, a movement area within which the sample processing apparatus moves, wherein the movement restricting section allows the sample processing apparatus to move on the base so as to change orientation of the sample processing apparatus, is disclosed. A base for a sample processing system and a sample processing apparatus are also disclosed.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: June 3, 2014
    Assignee: Sysmex Corporation
    Inventors: Yuichi Hamada, Keisuke Kuwano
  • Patent number: 8722424
    Abstract: In a chromatography quantitative measuring apparatus, a beam applied from a light source to a chromatography test strip is formed into an elliptical shape by an optical means such as a cylindrical lens, a variation in absorbance that accompanies elution of a marker regent is detected while the elliptical beam is applied between a marker reagent hold part and a detection part, and a measurement is automatically started in a prescribed period of time since the detection of variation. According to the chromatography quantitative measuring apparatus so configured, non-uniform coloration is reduced by shaping the beam elliptically with the optical means, whereby the accuracy of quantitative analysis is enhanced, and the apparatus can be operated easily.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: May 13, 2014
    Assignee: Panasonic Corporation
    Inventors: Koji Miyoshi, Masahiro Aga, Kaoru Shigematsu
  • Patent number: 8715589
    Abstract: Embodiments of the present invention relate to analyte sensors comprising a heparin coating, and methods of coating analyte sensors. The heparin can be stably associated with at least a portion of a porous membrane that covers a portion of the analyte sensors. The heparin can be photochemically linked to the coating through the formation of covalent bonds.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: May 6, 2014
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Matthew A. Romey, Soya Gamsey, David R. Markle