In A Holder Or Container Patents (Class 422/401)
  • Patent number: 11913949
    Abstract: The present invention relates to a multiparameter lateral flow strip (1), comprising a microporous membrane layer (2) supported on a liquid-impermeable support layer (3), for lateral flow of a liquid through the microporous membrane layer (2), wherein the microporous membrane layer (2) has two or more flow lanes (4) in the direction of lateral flow, wherein said two or more flow lanes (4) are separated by hydrophobic separation channels (5), and wherein each of said two or more flow lanes (4) comprises a detection spot (6) including a binding agent, wherein said two or more flow lanes (4) are isomorphic lanes. Furthermore, the present invention relates to a multiparameter lateral flow immunoassay device comprising said multiparameter lateral flow membrane (1), the use of said multiparameter configured lateral flow membrane (1) in an immunological test, as well as to a method for the manufacture of said multiparameter configured lateral flow membrane (1).
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: February 27, 2024
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Denise Van Rossum, Eric Jallérat, Susanne Drebing, Dieter Melzner
  • Patent number: 11845595
    Abstract: A container management system including a lid assembly configured to engage/disengage a collar of a container to close and open an aperture thereof, wherein the lid assembly includes an interior lid compartment in communication with an interior portion of the container when the lid assembly engages the collar, a reactive substance configured to undergo a physical change in response to a change of an environment condition at the aperture when the lid assembly engages the collar. The physical change of the reactive substance turns the lid assembly from a first operative condition wherein the lid assembly can be disengaged from the collar to open the aperture to a second operative condition wherein a portion of the lid assembly cannot be disengaged from the collar and closes the aperture.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: December 19, 2023
    Assignee: G.D S.P.A.
    Inventors: Anthony Puccini, András Selmeczy, Sip Hoo Liew, Enrico Bernardi, Gabriele Benni
  • Patent number: 11656225
    Abstract: An apparatus for testing a fluid sample including a sample receiving member having an opening for receiving a fluid sample, wherein the sample receiving member comprises at least a first and second sample collection chambers, a sample retention member, in fluid communication with the first sample collection chamber, to retain a portion of the fluid sample, and at least one test strip, in fluid communication with the second collection chamber, to indicate the presence or absence of at least one analyte in the fluid sample, wherein the first collection chamber is not in fluid communication with the second collection chamber.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: May 23, 2023
    Inventor: Raouf A. Guirguis
  • Patent number: 11536661
    Abstract: The present disclosure discloses an optochemical sensor for determining a measurand correlating with a concentration of an analyte in a measuring fluid, comprising: a housing having an immersion region configured for immersing in the measuring fluid; a removable cap having a sensor spot, the removable cap removably arranged at the immersion region of the housing, wherein the sensor spot is disposed on a circumferential face; a radiation source disposed in the housing for radiating excitation radiation into the removable cap, wherein a deflection module is disposed in the removable cap as to deflect excitation radiation radiated into the removable cap; a radiation receiver disposed in the housing for receiving received radiation emitted by the sensor spot; and a sensor circuit disposed in the housing and configured to control the radiation source, receive signals of the radiation receiver, and generate output signals based on the signals of the radiation receiver.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: December 27, 2022
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventors: Andreas Löbbert, Alexander Hörig
  • Patent number: 11385183
    Abstract: Cu(II) detection in the presence of main group heavy metal ions and d-, f- and g-element interferents relies on a colorimetric chelating complex between 3-hydroxy-5-nitrobenzaldehyde-4-hydroxybenzoylhydrazone (3-HNHBH) and Cu(II). Derivatives and entrapped forms of the probe were aligned with the methods of analysis, featuring spectrophotometric, reflectometric, lateral flow, microfluidic, lab-on-paper, positional array, dynamic array, flow cytometry and tandem stage devices. A remotely operating software capable of DFT calculations predicted the observed detection limit of 0.34 ?g L?1 (<5 nM) as well as high selectivity towards copper ions in the presence of competing Zn+2 and Ni+2. The probe was readily regenerated against metal complexation by using a 0.5 M HCl solution, indicating its feasibility to be a re-usable sensor for the convenient detection of copper ions in water-organic media.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: July 12, 2022
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Chanbasha Basheer, Abdulaziz A. Al-Saadi, Ismail Abdulazeez
  • Patent number: 11385146
    Abstract: Sampling systems and techniques that increase pickup efficiency and shedding efficiency of an analyst of interest collected from a surface are provided. In one aspect, an absorbent swab collects an analyte of interest, such as a hazardous contaminant, from a test area demarcated by a template. The sampling techniques can include swab speed and force protocols specifying how fast and how hard the user should apply the swab across the surface to improve pickup efficiency. The sampling techniques can include instructions for inverting a container enclosing the swab and collected contaminant to improve shedding efficiency from the swab.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: July 12, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Weston F. Harding, Austin Jason Mckinnon, Matthew Oshinski
  • Patent number: 11253235
    Abstract: A kit for urine collection is disclosed. The kit comprises a clip; a collector device comprising a connector portion configured for receiving the clip, a holder portion configured for receiving a sponge; and a stopper portion; a tube configured to receive the collector device; and a cap configured to be inserted onto an open end of the tube and seal the tube and simultaneously receive an end of the collector device into a recess disposed inside the cap.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: February 22, 2022
    Assignee: UrynX LLC
    Inventors: Brian Schwab, Cheng-Yang Lai
  • Patent number: 11231369
    Abstract: A single unit, handheld field portable apparatus and method for analyzing Ochratoxin A (OTA) in rice quality monitoring, based on fluorescence signal output. Aliquots may be analyzed by adding at least one or more reagents to the sample aliquot that reacts selectively with an analyte contained therein. The reaction product, which is selective for the analyte of interest and proportional to its concentration, is measured with an appropriate detector. This enables simple and accurate testing of samples using time honored wet-chemical analysis method in microliter volume regimes while producing remarkably small volumes of waste. The device includes a multipurpose controller board for processing and analysis purpose, a camera which is integrated with the controller, a resistive touch liquid crystal display to view the results, a light emitting diode to emit the UV light, and a power bank. The device may operate using a touch display.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: January 25, 2022
    Inventors: Akhtar Hayat, Muhammad Yaqoob Javed, Muhammad Umair Safder
  • Patent number: 11143651
    Abstract: A system and method of quantitating the concentration of a molecule of interest in one embodiment includes establishing a plurality of test environments at a plurality of test sites, each of the plurality of test environments associated with one of a plurality of response curves, each of the plurality of response curves different from the other of the plurality of response curves, storing a combined response curve resulting from a summation of the plurality of response curves, exposing the plurality of test sites to a sample having a concentration of a molecule of interest, obtaining a plurality of quantitation signals, each of the plurality of quantitation signals associated with one of the plurality of test sites, associating a summation of the plurality of quantitation signals with the stored combined response curve, and generating a signal related to the concentration of the molecule of interest based upon the association.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: October 12, 2021
    Assignee: Robert Bosch GmbH
    Inventors: Sam Kavusi, Michaela Laupheimer, Christoph Lang
  • Patent number: 11079317
    Abstract: Sensor for the optical detection of free hemoglobin (96) in a whole blood sample (99), the sensor comprising a translucent slab (2) with a front side (3) and a back side (4) facing away from the front side (3), wherein the front side (3) is adapted for being contacted with a whole blood sample (99); a reflective layer (5) at the front side (3) of the translucent slab (2), the reflective layer (5) being adapted to reflect light reaching the reflective layer (5) from the translucent slab (2); an optical probing device comprising a light source (10) and a detector (20), wherein the light source (10) is adapted to illuminate at least pores in the translucent slab, wherein the detector (20) is arranged to receive light (21) emerging from the pores (6) in response to an illumination (11) by the light source (10), and wherein the detector (20) is adapted to generate a signal representative of the detected light.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: August 3, 2021
    Inventor: Thomas Kjaer
  • Patent number: 11051606
    Abstract: An oral care implement that dispenses an oral care agent during use and a method of assembling such an oral care implement. The oral care implement may include a body having a head portion. The head portion may have a cavity with an open end. There may be at least one opening extending from the cavity to an outer surface of the head portion. A dissolvable element that includes an oral care agent may be positioned in the cavity. Furthermore, a supporting member may be positioned in the cavity. The supporting member may include a first coupling feature that couples the supporting member to the dissolvable element. Finally, an oral cleaning member may be coupled to the head portion to close the open end of the cavity.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: July 6, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Leighton Davies-Smith, Erin Speicher, Hallena Strotman
  • Patent number: 11002750
    Abstract: Method and apparatus for electronic detection and determination includes detecting a signal T0 in a detection zone and a signal R0 in a reference zone before a sample is added; adding a sample and detecting the signals in each of the detection zone and the reference zone at an interval of a second preset period; calculating a judgement value based on 2k immediately previous signals in each of the detection zone and the reference zone, the signal T0 in the detection zone before the sample is added, and the signal R0 in the reference zone before the sample is added, each time when k successive signals are detected in each of the detection zone and the reference zone; and determining a judgement result based on m successive judgement values and a preset result threshold corresponding to a current detection time.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: May 11, 2021
    Inventors: Haisheng Hu, Zanxun Cen, Guiyang Li, Hong Luo, Jihua Wang
  • Patent number: 10983065
    Abstract: A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: April 20, 2021
    Assignee: HEALTHY.IO LTD.
    Inventors: Bernard Burg, Martin Zizi, Walter De Brouwer, Jaime Tenedorio, Babak Aghazadeh, Jie Cui, Sheena Menezes
  • Patent number: 10870766
    Abstract: Provided is a carbon nanotube dispersion liquid that has excellent stability and that can be used to form a conductor film that exhibits excellent adhesiveness to a substrate. The carbon nanotube dispersion liquid contains carbon nanotubes (A), a polymeric dispersant (B) including a sulfonic acid group-containing monomeric unit and an ethylenically unsaturated aliphatic carboxylic acid monomeric unit, and a solvent (C). Percentage content of the ethylenically unsaturated aliphatic carboxylic acid monomeric unit in the polymeric dispersant (B) is greater than 20 mol % and no greater than 90 mol %.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: December 22, 2020
    Inventors: Akihiko Yoshiwara, Kiyoshige Kojima, Yasuo Mukunoki, Akihiro Kojima, Masashi Ikegami
  • Patent number: 10830721
    Abstract: Disclosed herein are embodiments of compositions for gas sensing and sensors utilizing the same. In one embodiment, a composition comprises carbon nanotubes and and polymer-coated metal nanoparticles bound to the carbon nanotubes.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: November 10, 2020
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Gabriel Iftime, Clinton Smith, David Eric Schwartz, Yong Zhang, Vedasri Vedharathinam
  • Patent number: 10828207
    Abstract: A system for removing and donning a disposable absorbent article by using a separate robotic device includes an absorbent assembly having an inner layer that partly defines a body-facing surface, an outer layer that defines a garment-facing surface, and an absorbent body disposed between the inner and outer layers. The absorbent assembly also includes a pair of ears extending transversely outward from the opposite sides of the absorbent assembly in the back waist region, each of the ears including a body-facing surface with a primary first fastening-component that is selectively engageable with a primary second fastening-component in the front waist region of the absorbent assembly in a wear configuration of the article, and a garment-facing surface opposite the body-facing surface. The absorbent article also includes a manipulation-enablement feature configured to assist the post-retail manipulation of the absorbent article by the robotic device.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: November 10, 2020
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Andrew Mark Long, Shawn J. Sullivan, Chris P. Olson
  • Patent number: 10816542
    Abstract: A tear glucose measuring device includes a tear glucose test strip (101) and a reaction device, wherein the tear glucose test strip (101) is used for collecting tears which are then subjected to an elution reaction with a glucose assay reagent contained in the reaction device. With this device, a user can collect tears by himself by folding a leading portion (1014) of the tear glucose test strip (101) about a folding line (1021) and inserting the leading portion (1014) into the lower conjunctival sac inside the lower eyelid to allow the absorbance of tears therein. If tear glucose test strips (101) of the same lot are consistent in terms of thickness of a moisture-absorbent layer of the leading portion (1014), as long as a tear collection region (1020) of the leading portion (1014) has a fixed area, the leading portion (1014) can collect a quantitative amount of tears.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: October 27, 2020
    Inventor: Jianhui He
  • Patent number: 10794911
    Abstract: A system and method for detecting status of a health condition in a single-step process includes: a signal output device including a) a loading zone; b) a reaction zone fluidly coupled to the loading zone and including one or more reaction substances conjugated to labels, configured to enable detection of target material associated with the health condition; c) a testing zone fluidly coupled to the reaction zone and including one or more testing substances corresponding to the target material; and d) a control zone including a control substance retained at the control zone. The system and methods can be adapted for assessment of sexual health of one or more subjects, in relation to pregnancy, fertility, and/or sexually transmitted infections caused by one or more agents including, Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Treponema pallidum, Gardnerella vaginitis, human immunodeficiency virus, human papillomavirus infection, Hepatitis B, and herpes simplex virus.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: October 6, 2020
    Inventors: Sheena Ruby Menezes, Jerzy Majka, Linus Ryan Aranha, Quynh Nga Thi Le
  • Patent number: 10768171
    Abstract: A disposable test kit comprising a base sheet; a sealing sheet having at least one sealed sample collection opening before use of the test kit; at least one test strip sealed between the base sheet and the sealing sheet before use of the test kit; and at least one top sheet layered over the sealing sheet before use of the test kit to keep the at least one sample collection opening sealed, the at least one top sheet further configured to be at least partially detached from the sealing sheet to open the at least one sample collection opening and expose a sample collection portion of the at least one test strip for receiving a fluid analyte thereon during use of the test kit.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: September 8, 2020
    Assignee: CELL ID PTE LTD
    Inventor: Lye Hock Sim
  • Patent number: 10739337
    Abstract: The disclosure relates to the extraction and detection of pathogens using carbohydrate-functionalized biosensors. Immobilized carbohydrate moieties on the biosensor provide a means for non-specific binding of a plurality of target analytes. When a sample containing the target analyte is applied or otherwise transported to the biosensor detection surface, non-specific binding interactions between the carbohydrate moiety and the analyte immobilize/retain the analyte at the detection surface. The carbohydrate moiety is a stable binding pair member that allows on-sensor rinsing of a sample to enhance detection of an analyte in the sample. Specific analyte identification can be achieved with an analyte probe having a detection moiety and a binding pair member specific to the target analyte of interest.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: August 11, 2020
    Inventors: Evangelyn C. Alocilja, Barbara Christine Cloutier, Michael J. Anderson
  • Patent number: 10736612
    Abstract: Various embodiments of a swab device, system, and method are provided for measuring and assessing saliva flow in the mouth of a person. In one embodiment, a system includes a swab device and a measuring device. The swab device includes a handle portion and a swab portion, the handle portion being elongated to extend between a proximal end and a distal end. The swab portion is coupled to a distal portion of the handle portion and is sized and configured to collect saliva from the mouth. The measuring device is sized and configured to measure an amount of the saliva collected with the swab portion, the measuring device including a nesting portion integrated therewith. Such nesting portion of the measuring device is sized and configured to receive the proximal end of the handle portion of the swab device to measure the saliva collected therewith.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: August 11, 2020
    Assignee: BOKA SCIENCES, INC.
    Inventors: Grant J. Donovan, Jeffrey A. Stern, Ryan C. Patterson, James A. Malmstrom, Kent F. Beck, Scott D. Miles
  • Patent number: 10732119
    Abstract: Disclosed are a biochip for measuring blood glucose levels and a blood glucose meter for a smartphone including the same. The biochip for measuring blood glucose levels includes: a substrate, one surface of which is provided with a blood glucose inflow region into which blood glucose flows and with a reaction region that is connected to the blood glucose inflow region and has a recess formed therein, a porous separator disposed on the blood glucose inflow region to face the surface of the substrate, and silica nanoparticles and a reaction reagent distributed on the reaction region of the substrate. Thereby, blood glucose levels can be measured using such a biochip, which is easy to carry, together with a CMOS image sensor, and particularly, blood glucose levels can be simply measured using a CMOS image sensor provided to a smartphone, and blood glucose levels can be quantitatively measured and checked using a blood glucose meter application installed on a smartphone.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: August 4, 2020
    Inventor: Sanghyo Kim
  • Patent number: 10653397
    Abstract: Disclosed is a device useful for preserving tissue samples after extraction from human or animal patients. The device includes a circular blade for taking a tissue sample, the blade being coupled to a sealing cap which mates to one end of a container. A retrieval port is also disclosed for extracting fluids from the container. Methods are also disclosed by which tissue samples may be taken and prepared for storage, processing, culture, or other analysis.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: May 19, 2020
    Assignee: Gallant Pet, Inc.
    Inventors: Erik J. Woods, Shelly J. Zacharias
  • Patent number: 10613105
    Abstract: The invention relates to a competitive immunoassay test system as well as a method to simply and rapidly detect pyrogens contained in a sample by means of the pyrogen binding domain of pattern recognition receptors. The test system comprises an assay carrier having at least one immobilized pyrogen binding domain of a pattern recognition receptor with a labeled, displaceable ligand, wherein the displacement of the ligand is indicated by a pyrogen contained in the sample by a color reaction of the labeling. The assay carrier preferably also has at least one immobilized ligand capture protein, which binds the displaced ligand and thereby initiates a color reaction of the labeling.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: April 7, 2020
    Inventors: Anke Burger-Kentischer, Steffen Rupp
  • Patent number: 10598656
    Abstract: Lateral flow devices and methods of use for a molecular diagnostic assay are provided. The method is suitable for detection or monitoring of targets, including biological, chemical, and material targets that exist in very low concentrations in biological samples. The methods and devices of the present application are amenable to power source-free point of care testing.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: March 24, 2020
    Inventors: Winston Wong, Jr., Stephen Chang-Chi Kao
  • Patent number: 10591474
    Abstract: Systems and methods for low-cost point-of-care immunoassay are provided. The system comprises an emitter, two optical interference filters, a microscope slide, a photodiode detector, a circuit, and a measuring unit. The detector is placed upon the second filter, the slide, the first filter, and then the emitter. The emitter comprises non-organic light emitting diodes (LEDs) or organic light emitting diodes (OLEDs) that emits light of a first color. The slide is spotted with biofluid from a patient. Biomarkers in the biofluid is bound with immobilized fluorophores that emit light of a second color when stimulated by the light of the first color. The first and second filters band-pass the light of the first and second colors, respectively. The detector detects light of the second color. The current outputted from the detector is converted into a relatively-large output voltage by a circuit. A measuring unit measures the ramp time of the output voltage.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: March 17, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Benjamin Katchman, Karen Anderson, Joseph Smith, Jennifer Blain Christen
  • Patent number: 10533932
    Abstract: The present disclosure provides apparatus and methods for processing liquids or fluids. Such apparatus and methods are convenient and efficient for low-cost separation, filtration, capture, collection, and/or storage of biologics and related materials. Provided apparatus and methods are designed for point-of-care use and offer advantages for patients and medical practitioners, including advantages in diagnosis and long-term monitoring of conditions.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: January 14, 2020
    Inventors: Per Guldberg, Kenneth Eric Steven
  • Patent number: 10473648
    Abstract: Provided is a biosensor including a capillary unit having a capillary channel therein and a reagent disposed in the capillary channel, the reagent being configured to develop colors in a sample, and a measuring unit configured to measure a degree of color development of the sample in the capillary channel.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: November 12, 2019
    Inventors: Young Jun Kim, Wan Joong Kim, Bong Kyu Kim
  • Patent number: 10453566
    Abstract: A method for analyzing diabetes related information by a diabetes management application residing on a computing device. The method may include: receiving a data entry over a communication link from a blood glucose meter, where the data entry includes a glucose measurement and an indicator of a pre-established activity associated with the glucose measurement; evaluating the data entry in relation to a subject structured test based in part by comparing the indicator from the data entry with collection events associated with the subject structured test; identifying the data entry as compatible with the subject structured test when the data entry correlates with a given collection event specified by the subject structured test; identifying the data entry as non-compatible with the subject structured test when the data entry does not correlate with the given collection event specified by the subject structured test; and inputting the data entry into a logbook.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: October 22, 2019
    Assignee: Roche Diabetes Care, INc.
    Inventors: Robert E. Reinke, Jose Salazar-Galindo
  • Patent number: 10434248
    Abstract: Protein detection kit usable with implanted infusion pumps. The kit includes at least one container containing a protein-detecting composition and having an interface for allowing fluid to be introduced and a visual indicating mechanism for providing a visual indicator indicative of protein detection.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: October 8, 2019
    Assignee: Saol International Limited
    Inventors: David Allen Penake, Sharon Hamm, Martin Reynell
  • Patent number: 10390804
    Abstract: Sample collection apparatus and methods of sample collection are provided, for example saliva collection apparatus and methods of saliva collection. Said apparatus conveniently comprises a filter assembly and an interface for delivering material from the apparatus to an assay unit.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: August 27, 2019
    Inventors: Monica Silverstone Spiteri, Neil Patel
  • Patent number: 10371693
    Abstract: A portable blood glucose measurement device is provided. The device includes, in an externally exposed way, a temperature measurement medium of which the temperature quickly changes according to outside temperature changes provided on one side surface of a case. The device further includes an infrared temperature sensor. The device measures the temperature of the temperature measurement medium with the infrared temperature sensor in a noncontact manner, and calculates a blood glucose measurement result by considering the measured temperature so as to accurately reflect the outside temperature of an actual blood glucose measuring environment. The temperature measurement medium can be configured to sensitively respond to the outside temperature independently from the case such that the temperature of the temperature measurement medium, in accordance with the change in outside temperature, quickly and accurately changes so as to measure the temperature in a more accurate manner.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 6, 2019
    Assignee: I-SENS, INC.
    Inventors: Jin Won Lee, Chang Woo Ryu, Geun Sig Cha, Hak hyun Nam
  • Patent number: 10278624
    Abstract: A method for providing a assistance for maintaining or improving an individual's wellness, comprising the steps of measuring a presence and/or concentration of one or more biomarkers in a sample from the individual; predicting a wellness need for maintaining or improving the individual's wellness based on the measured presence and/or concentration of the one or more biomarkers, wherein the one or more biomarkers are indicators of the wellness need; and altering the living environment of the individual, providing a wellness product or service to the individual or providing information, guidance or advice to the individual for addressing the wellness need of the individual. A system providing assistance for maintaining or improving an individual's wellness is also provided.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: May 7, 2019
    Assignee: IPHENOTYPE LLC
    Inventors: Jay M. Short, Steve Briggs
  • Patent number: 10273523
    Abstract: An assembly for preparing a specimen is provided that may be configured to determine the presence of at least one microorganism specie in the specimen. The assembly may include a pipette configured to acquire a specimen from a sample and an imaging cartridge configured to be in fluid communication with the pipette. The imaging cartridge and the pipette may be configured to be irreversibly coupled such that the specimen is bio-contained within the imaging cartridge and the pipette when the imaging cartridge and pipette are coupled together. Associated methods of use are also provided.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: April 30, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Alexander George Lastovich, Anita Quinn, Pauline Elizabeth Bell, James Lee Schram, Rex Young Nielson, Jason Paul Hayes, Matthew James Springer, Lincoln Belcourt, Matthew Daniel Solomon
  • Patent number: 10258278
    Abstract: A hydration sensor or sensing element is configured to measure the hydration level of a user. The sensing element can include a water-permeable material positioned in between two water-impermeable materials. The sensing element can be coupled to a bottle of fluid, or a carrier with a timer. The sensing element can be incorporated into a handheld device. The sensing element can be a disposable element, an element applicable for more than one-time use, or a re-usable element. The sensing element or sensor can be calibrated for a specific user or a group of users. One or more additional sensors that do not measure hydration level of the user can be coupled to a hydration sensing element to determine the amount of fluid consumption for the user in different conditions.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: April 16, 2019
    Assignee: IpVenture, Inc.
    Inventors: Thomas A. Howell, Angeline Hadiwidjaja, Peter P. Tong, C. Douglass Thomas, Corrine Schrall
  • Patent number: 10197495
    Abstract: A urine screen and urine analysis method for analyzing urine color to determine the hydration level of an individual. The urine screen is nonabsorbent. The urine screen includes a base member, a urinal dish, and a color scale. The urinal dish has a side wall that extends from the front side of the base member. The urinal dish is open at the top portion and is able to receive fluid into the urinal dish through the open top portion. The urinal dish includes a small drain hole. The color scale is applied to the front side of the base member and includes at least a plurality of shades of yellow. Each of the shades of yellow corresponds to a hydration level based on urine color.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: February 5, 2019
    Inventor: Daniel Gordon Drury
  • Patent number: 10184937
    Abstract: A system and method for determining the presence and level of allergy indicators in a human fluid sample such as, but not limited to, blood serum and saliva, is disclosed. In another embodiment, the method may assess a level of allergens in a consumable product. The system and method may make use of functionalized magnetic nanoparticles that have modified surfaces suitable for attracting allergy indicators from human fluid sample and allergens from consumable products. The system and method may provide a minimally invasive assessment of allergy indicators to determine whether one is allergic to a substance.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: January 22, 2019
    Assignees: United Arab Emirates University, University Of North Carolina At Greensboro
    Inventor: Yousef Haik
  • Patent number: 10124339
    Abstract: A composite collection device suitable for the collection of fluid samples is disclosed. The device is suitable for the collection of a multitude of fluid samples, including biological fluids like blood, urine, saliva, plasma specimens for subsequent determination of analytes contained therein. An accurate volume fluid collection card system with a single or multiplicity of cells comprises three strata, a middle absorbent stratum, layered between an impermeable cover stratum containing at least one aperture and a transparent stratum containing indicia. The aperture in the impermeable cover stratum directs the fluid onto the middle absorbent. The middle absorbent stratum contains no alterations. The transparent stratum contains indicia that indicate the extent of the absorption of the fluid.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: November 13, 2018
    Assignee: OpAns LLC
    Inventors: Kenneth Cranford Lewis, Tina Carol Guilliams Baxter
  • Patent number: 10048193
    Abstract: A curved surface is placed tangent to a slide and displaces a sample liquid from the point or line of contact outward. Imaging indicates a region where fluorescence is observed, and the location of the fluorescence indicates the molecular size. The radius of curvature of the lens is known, the distance from the (center) point of contact of the observed fluorescence is measured with a microscope and the distance of the lens surface to the slide's surface can then be calculated. This distance represents the size of the molecule or ensemble of molecules emitting. Similarly, absorbance, etc. could be measured with a light source below the slide.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: August 14, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Adam E. Cohen, Sabrina R. Leslie
  • Patent number: 10007106
    Abstract: An optical filter includes a stationary substrate and a movable substrate disposed so as to be opposed to each other, a first reflecting film disposed on a movable substrate side of the stationary substrate, a second reflecting film disposed on a stationary substrate side of the movable substrate, and opposed to the first reflecting film, a first protective film disposed so as to overlap the first reflecting film, and having a light transmissive property and electrical conductivity, a second protective film disposed so as to overlap the second reflecting film, and having a light transmissive property and electrical conductivity, a first terminal connected to the first protective film, and a second terminal connected to the second protective film. An electrical connection of the first terminal and the second terminal is electrically switchable.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: June 26, 2018
    Assignee: Seiko Epson Corporation
    Inventors: Susumu Shinto, Koji Kitahara
  • Patent number: 9995703
    Abstract: A device for detecting chemical or biochemical substances in fluids for use in an electrochemical camera. The device includes a first carrier having a sensor array with a plurality of electrochemical sensors. A second carrier includes a porous layer having at least one functional region, in which specifically binding capturing molecules are immobilized. The at least one functional region is arranged directly adjacent to at least one non-functionalized region. Assigned to the at least one functional region and the at least one non-functionalized region are several sensors of the sensor array, for use as the electrochemical camera.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: June 12, 2018
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Alexander Frey, Walter Gumbrecht, Peter Paulicka, Meinrad Schienle, Manfred Stanzel
  • Patent number: 9976984
    Abstract: Provided are devices that include a support, a free-standing polymeric separation medium associated with the support and configured to separate a sample along a directional axis, and a sample-loading element associated with the polymeric separation medium. Systems that include the devices, as well as methods of using the devices, are also provided. Embodiments of the present disclosure find use in a variety of different applications, including detecting whether an analyte is present in a fluid sample.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: May 22, 2018
    Assignee: The Regents of the University of California
    Inventors: Amy E. Herr, Todd Duncombe
  • Patent number: 9957500
    Abstract: A continuous flow nucleic acid extraction apparatus comprising a piston column apparatus for the extraction of nucleic acids from a nucleic acid sample. The disclosure also includes a method of using the continuous flow nucleic acid extraction apparatus.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: May 1, 2018
    Assignee: Stem Arts Projects, LLC
    Inventors: Abraham Oommen, Matthew Greenleaf, Adam Koch
  • Patent number: 9957545
    Abstract: A blood glucose measurement unit, a blood glucose measurement method, and a blood glucose measurement system comprising the same are disclosed. According to one aspect of the present invention, provided is a blood glucose measurement unit comprising: a transparent first substrate consisting of a blood inflow region into which blood flows and a reaction region connected to the blood inflow region which are formed on one surface thereof; a transparent second substrate coupled to the first substrate and comprising a blood aperture through which the blood flowing into the blood inflow region passes; and a reagent distributed to the reaction region so as to react with the blood glucose of the blood which has flown into the blood inflow region.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: May 1, 2018
    Inventor: Sanghyo Kim
  • Patent number: 9945789
    Abstract: A multiple analyte detection system includes a carrier having reagents disposed thereat, with each of the reagents capable of optically changing in response to exposure to a respective analyte. The system further includes a photodetector positioned to collectively detect light interacted with each of the reagents, a processor to determine a presence or an absence of each of the analytes in response to the light collectively-detected, and an indicator to provide an indication of the presence or the absence of each of the analytes. A method of detecting multiple analytes includes exposing reagents capable of optically changing in response to exposure to a respective analyte to a sample. The method further includes collectively detecting light interacted with each of the reagents, determining a presence or an absence of each of the analytes in response to the light collectively detected, and indicating the presence or the absence of each of the analytes determined.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: April 17, 2018
    Assignee: Alverix, Inc.
    Inventors: Ian Hardcastle, Carol T. Schembri, John Francis Petrilla, Rene B. Helbing, Daniel B. Roitman
  • Patent number: 9897526
    Abstract: A vacuum apparatus includes a vacuum chamber, first sensor units disposed in the vacuum chamber facing a deposition direction of particles, and second sensor units disposed in the vacuum chamber, each disposed on a corresponding first sensor of the first sensor units facing the deposition direction, wherein the first sensor units are configured to sense a pressure in the vacuum chamber and an absorption amount of the particles adsorbed to the first sensor units, and the second sensor units are configured to sense the pressure in the vacuum chamber.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: February 20, 2018
    Assignee: Samsung Display Co., Ltd.
    Inventors: Eun-Ju Song, Hoonchul Ryoo
  • Patent number: 9857363
    Abstract: Disclosed herein are a membrane sensor capable of changing a reaction condition by a single sample injection and a method for measuring a reaction using the same, and more specifically, a membrane sensor designed so that a bio reaction having two or more reaction conditions is sequentially generated by a single sample injection, by forming an asymmetric membrane between a reactant storing part and a reaction membrane.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: January 2, 2018
    Assignee: INGIBIO, LTD.
    Inventors: Min-Gon Kim, Hyou-Arm Joung, Jun-Hyoung Ahn
  • Patent number: 9829422
    Abstract: A concentration meter invention includes a housing having a cavity, an electrode accommodated in the cavity, a permeation membrane that has a measurement surface that contacts a measurement target, a releasing surface that releases the measurement target that enters from the measurement surface into the cavity, and a plurality of holes that open to the measurement surface and the releasing surface, and are for the measurement target to enter, and seals the cavity, an internal liquid that is sealed in the cavity, and contacts the electrode and the permeation membrane, an adjustment section that applies a mechanical load to the permeation membrane so that opening areas of the holes in at least the measurement surface reversibly increase or decrease, and a control section that is connected to the adjustment section, and controls change of strength of the mechanical load that is applied to the permeation membrane.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: November 28, 2017
    Inventor: Hideto Onishi
  • Patent number: 9816903
    Abstract: Disclosed is a filtration device for liquid samples as well as a close and push-through device for said filtration device.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: November 14, 2017
    Inventors: Andrea Frisse, Andreas Graus
  • Patent number: 9757718
    Abstract: Catalytic articles having a high porosity substrate containing platinum, palladium or a mixture thereof, in walls of the high porosity substrate and an SCR catalyst coating on a wall of the high porosity substrate are disclosed. The platinum, palladium or mixture thereof can be present in the wall of the high porosity support as a metal, or as a supported platinum, palladium or a mixture thereof. The catalytic articles are useful for selective catalytic reduction (SCR) of NOx in exhaust gases and in reducing the amount of ammonia slip. Methods for producing such articles are described. Methods of using the catalytic articles in an SCR process, where the amount of ammonia slip is reduced, are also described.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: September 12, 2017
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Joseph Michael Fedeyko, Hai-Ying Chen