Of Liquid Patents (Class 422/41)
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Patent number: 6749809Abstract: A clustered creature exterminating method efficiently exterminates clustered creature such as cyanobacteria in large quantity with use of a pressure which is substantially lower than that of the conventional method. The exterminating method includes the steps of: pressurizing a fluid containing a clustered creature such as cyanobacteria through a pump; suddenly lowering the pressure applied to the fluid by injecting the fluid from nozzle groups; and destroying a bonding in the clustered creature by a cavitation caused by the pressure drop. The nozzle groups may be arranged to oppose to one another to collide the injected fluids with each other, which divides the cyanobacteria into many small pieces. As a result, the cyanobacteria lose the ability to rise, and sink at the bottom of water, therefore, die because they cannot photosynthesize.Type: GrantFiled: September 17, 2001Date of Patent: June 15, 2004Assignee: Karasawa Fine, Ltd.Inventor: Yukihiko Karasawa
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Patent number: 6716457Abstract: The present invention relates to a process for inhibiting or eliminating the growth of microorganisms in pesticide suspensions. More particularly, the process of the present invention includes the addition of a combination of peracetic acid, hydrogen peroxide, and water to the pesticide suspension. Further, the process of the present invention includes the application of the peracetic acid, hydrogen peroxide, and water combination to the interior surface of the vessel in which the pesticide suspension is contained. Still further, the process of the present invention includes the application of the peracetic acid, hydrogen peroxide, and water combination to a surface in which the pesticide suspension is in contact.Type: GrantFiled: October 17, 2000Date of Patent: April 6, 2004Assignee: Bayer Polymers LLCInventors: Karen L. Eagles, Donald W. Edson, Kevin Park, John G. Rogers, John W. Brandriff, Stephen C. Slahck
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Patent number: 6692695Abstract: This invention relates to barrier methods for preserving sensitive biological materials as a porous foam, subsequently crushing the foam to form a powder, and optionally formulating mixtures of preserved powdered biological materials. The invention also encompasses an apparatus for integrating the methods of foam formation and subsequent crushing of the preserved biological materials using barrier technology.Type: GrantFiled: June 7, 2000Date of Patent: February 17, 2004Assignee: Quadrant Drug Delivery LimitedInventors: Victor Bronshtein, Kevin R. Bracken, Ronnie K. Livers, David R. Williams
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Patent number: 6686004Abstract: Packaging comprising a fluorochrome sensitive to visible light placed in a bottle of which at least the side walls form an effective screen against light spectrum radiation between 200 and 900 nm and a process for protecting fluorochromes sensitive to visible light during storage, in which said fluorochromes are placed in a bottle of which at least the side walls form an effective screen against light spectrum radiation between 200 and 900 nm.Type: GrantFiled: December 17, 2001Date of Patent: February 3, 2004Assignee: ImmunotechInventors: Jean-Pierre Daziano, André van Agthoven
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Patent number: 6663829Abstract: Methods and apparatus are disclosed for reducing the degradation of heat sensitive components contained in a medical substance during heat sterilization of a heat sterilizable container including a first chamber including a first amount of a first medical substance and a second chamber including a second amount of a second medical substance, the first amount being greater than the second amount. The method includes heating the heat sterilizable container to a first predetermined temperature for sterilizing the first and second medical substances, thermally insulating the second chamber during at least a portion of the heating of the heat sterilizable container to the first predetermined temperature, holding the heat sterilizable container at the first predetermined temperature for a first predetermined time period, and cooling the heat sterilizable container thereafter.Type: GrantFiled: April 5, 2001Date of Patent: December 16, 2003Assignee: Gambro ABInventor: Per Kjellstrand
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Patent number: 6660698Abstract: Compositions and methods for emulsifying a petroleum product that has been spilled upon a portion of the earth's surface or that is burning are based upon use of a nonionic, primary surfactant composition comprising a first ethoxylated sorbitol oleate and, preferably, a second ethoxylated sorbitol oleate, and a nonionic, secondary surfactant that is capable of stabilizing and solubilizing the primary surfactant composition such that the resulting emulsifying compositions have a hydrophilic/lipophilic balance between about 12.0 and about 13.5.Type: GrantFiled: October 29, 2001Date of Patent: December 9, 2003Assignee: Hans AchtmannInventor: Peter Riley
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Patent number: 6623787Abstract: A method for preventing a carbon dispersion from increasing in viscosity during use is described. The dispersion comprises graphite particles or carbon black particles or a combination of both dispersed in a fluid. The method involves lowering the susceptibility of the carbon dispersion to an increase in viscosity or ionic strength by lowering its pH or reducing its exposure to reactive components in the ambient atmospheric gas. The pH can be lowered by at least partially removing ammonia from the dispersion, or by adding a material that reduces the pH of the dispersion. The stability of the dispersion can also be improved by isolating the dispersion from reactive atmospheric gas. The stabilized aqueous carbon dispersion can have a viscosity of less than about 20 cps and a conductivity of less than about 3 mS.Type: GrantFiled: July 26, 2001Date of Patent: September 23, 2003Assignee: Electrochemicals Inc.Inventors: Joseph S. Bowers, Jr., Roger F. Bernards
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Patent number: 6602464Abstract: A method and apparatus are provided for minimizing the emissions of odorous gases and fatty acids generated by digestible and odiferous waste. The apparatus includes a treatment comprising oil, activated carbon and a base buffering agent. The apparatus also includes a system for delivering the treatment through a low pressure output, such as a low pressure manifold with a plurality of delivery pipes. A starter plank made of concrete, used for mounting the apparatus on a wall and a flotation board, made of foamed polystyrene board, directs the flow of the treatment onto the surface of the waste. The method includes the steps of applying oil and activated carbon to the surface of liquid waste and injecting a base buffering agent below the surface of the oil/activated carbon layer. The oil and activated carbon create a seal that prevents odorous emissions from entering the air space above the liquid waste and the base buffering system neutralizes the acidic waste.Type: GrantFiled: October 2, 2000Date of Patent: August 5, 2003Inventors: Gary L. Rapp, Carrie L. Rapp
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Patent number: 6579583Abstract: The invention provides a flexible plastic formulation capable of being extruded, blow-molded, ethylene oxide and radiation sterilized. The plastic formulation of the invention comprises: a) from about 60 to about 94 percent by weight of a copolymer consisting essentially of ethylene and vinyl acetate units; b) from about 5 to about 25 percent by weight of a block copolymer, the block copolymer consisting essentially of a central block copolymer molecule including generally equal proportions of ethylene and butylene units, and terminal blocks of polystyrene; and c) from about 1 to about 15 percent by weight of an ultra-low density polyethylene material. The plastic formulations of the invention are useful in the manufacture of blood bags, tubing and the like.Type: GrantFiled: November 13, 2001Date of Patent: June 17, 2003Assignee: Baxter International Inc.Inventor: Indrajit Patel
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Patent number: 6579494Abstract: A device for preparing a sterile liquid includes structure for validating a sterilization treatment applied to the liquid. The validating structure includes structure for calculating, from at least one operating parameter of the device, a parameter representing a sterilizing value for the sterilization treatment, and structure for comparing the calculated parameter to a threshold value corresponding to the sterility of the liquid.Type: GrantFiled: March 29, 2000Date of Patent: June 17, 2003Assignee: Hospal IndustrieInventors: Jacques Chevallet, Thierry Court, Michael John Dunkley, Alain Frugier, Lennart Jonsson, Nicholas John Kerry, Hiram Rada, Jean-Louis Romarie
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Patent number: 6475529Abstract: The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts—an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.Type: GrantFiled: July 30, 2001Date of Patent: November 5, 2002Assignee: Baxter International Inc.Inventors: Annick Duponchelle, Dirk Faict, Patrick Balteau, Jean-Pierre Hartman, Leo Martis, Francesco Peluso
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Patent number: 6440372Abstract: A system dynamically adjusts the delivery rate of a cryopreservation solution to red blood cells to permit freezing. The delivery rate is preferably determined according to an equation that maintains a linear change of red blood cell osmolarity over time so as to prevent osmolarity shock of the red blood cells. In the preferred embodiment, the system includes a controller that is preconfigured to automatically deliver the cryopreservation solution to the red blood cells in accordance with the equation. The system may also support the recovery of thawed red blood cells by diluting the red blood cells and washing them of the cryopreservative. Again, the system preferably adjusts the delivery rate of a dilution solution so as to prevent osmolarity shock of the red blood cells during the recovery phase. The recovered red blood cells may be suspended in a preservation solution to further increase their shelf-life following the recovery phase.Type: GrantFiled: July 30, 2001Date of Patent: August 27, 2002Assignee: Haemonetics CorporationInventor: Etienne Pages
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Stable oxidizing bromine formulations, method of manufacture and uses thereof for biofouling control
Patent number: 6423267Abstract: Stable biocide formulations containing oxidizing bromine are provided for biofouling control in industrial water systems. The formulations contain at least one stable oxidizing bromine compound that is prepared from at least one oxidizing chemical reagent, at least one bromine source and at least one bromine or halogen stabilizer. The resulting products are a mixture of stable oxidizing bromine compounds that can be used as a biocide in an industrial water system.Type: GrantFiled: March 2, 2000Date of Patent: July 23, 2002Assignee: Nalco Chemical CompanyInventors: Shunong Yang, William F. McCoy, Anthony W. Dallmier -
Patent number: 6413786Abstract: A device and a method enable the rapid, quantitative evaluation of a large collection of ligands for binding affinity with a certain immobilized receptor, the improvements being that binding pan be detected without the need for a label and that binding is carried out in solution phase at a high rate. The instrument has at least two embodiments, one is based on a sensitive absorption photometer and the other on a sensitive light scatter photometer operating at a specific resonance wavelength, &lgr;R, of small, metallic, colloidal particles. The resonance is present in small particles having a complex refractive index with real part n(&lgr;) approaching 0 and imaginary part k(&lgr;) approaching 2 simultaneously at a specific wavelength &lgr;R. The particles are substantially spherical and substantially smaller than &lgr;R. The receptor is immobilized on a suspension of such particles and ligand binding is detected by a change in optical absorption or light scatter at the resonance wavelength.Type: GrantFiled: August 11, 1999Date of Patent: July 2, 2002Assignee: Union Biometrica Technology Holdings, Inc.Inventors: W. Peter Hansen, Petra Krauledat
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Patent number: 6331272Abstract: Microorganisms are destroyed and enzymes can be inactivated in liquids, such as juices for example, by continuously flowing the liquid and continuously flowing pressurized dense CO2 along flow paths which are separated by membrane having minute pores at which the flows contact each other in a nondispersive manner. Pressures in the two flow paths are equalized and the dense CO2 flow is continuously recirculated without depressurization. Contact between the flows can be maximized by using a plurality of parallel hollow fiber porous membranes with one of the flows being directed into the hollow fibers and the other of the flows being directed along exterior surfaces of the fibers. The process does not adversely affect properties of the liquid, such as taste, aroma and nutritional content, as heating of the liquid to a high temperature is unnecessary.Type: GrantFiled: January 12, 1999Date of Patent: December 18, 2001Assignee: Porocrit, L.L.C.Inventor: Marc Sims
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Patent number: 6326010Abstract: To provide a plastic vessel containing an albumin preparation which completely restrains formation of thermally denatured albumin, a plastic molded member in a cylindrical shape is extruded in a molten state into opened dies, one end of which is closed in the dies, and a vessel is molded by blowing a compressed gas into the molded member in the dies or by bringing inner portions of the dies into a vacuum state. While the vessel is still disposed in the dies, an albumin preparation is introduced from an opening portion into an inner portion of the vessel and, therefore, the albumin preparation can be filled into the vessel in a sterilized state without being brought into contact with the atmosphere. Then, an opening portion of the vessel filled with the albumin preparation is hermetically sealed at an internal temperature of the opening portion of about 40 to 70° C. Thus formation of thermally denatured albumin can be completely restrained.Type: GrantFiled: October 25, 2000Date of Patent: December 4, 2001Assignee: Nipro CorporationInventors: Minoru Sano, Yoshihisa Hama, Toshiya Kai, Masakazu Mameta
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Patent number: 6306352Abstract: The present invention provides an effective oxygen generating materials, carbon dioxide absorbing materials, and transport system and transport method of live fishery products for use upon transporting live fishery products. An oxygen generating materials of the present invention is prepared by packaging solid peroxide and peroxide decomposition catalyst with a moisture-permeable material having a cup method moisture permeability (40° C., 90% RH) of more than 20 g/m2/24 hr and being impervious to water at normal pressure. Furthermore, a carbon dioxide absorbing materials are prepared by packaging alkaline earth metal hydroxide and/or oxide with a gas-permeable material having a Gurley method gas permeability (JIS P8117) of 0.1˜3000 sec./100 ml of gas and being impervious to water at normal pressure.Type: GrantFiled: September 25, 1998Date of Patent: October 23, 2001Assignee: Mitsubishi Gas Chemical Company, Inc.Inventors: Kiyoshi Yoshida, Yasuo Hiro, Jun Kokubo, Chiharu Nishizawa, Susumu Watanabe
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Patent number: 6306345Abstract: This invention relates to barrier methods for preserving sensitive biological materials as a porous foam, subsequently crushing the foam to form a powder, and optionally formulating mixtures of preserved powdered biological materials. The invention also encompasses an apparatus for integrating the methods of foam formation and subsequent crushing of the preserved biological materials using barrier technology.Type: GrantFiled: May 6, 1999Date of Patent: October 23, 2001Assignee: Universal Preservation Technologies, Inc.Inventors: Victor Bronshtein, Kevin R. Bracken, Ronnie K. Livers, David R. Williams
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Publication number: 20010010802Abstract: Venous reservoirs are interposed between the patient and the arterial pump and serve to remove air bubbles and provide compliance that accommodates variations in the volume of blood circulating in the extracorporeal circuit during cardiopulmonary bypass (CPB).Type: ApplicationFiled: February 28, 2001Publication date: August 2, 2001Inventor: Yehuda Tamari
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Patent number: 6267925Abstract: A system dynamically adjusts the delivery rate of a cryopreservation solution to red blood cells to permit freezing. The delivery rate is preferably determined according to an equation that maintains a linear change of red blood cell osmolarity over time so as to prevent osmolarity shock of the red blood cells. In the preferred embodiment, the system includes a controller that is preconfigured to automatically deliver the cryopreservation solution to the red blood cells in accordance with the equation. The system may also support the recovery of thawed red blood cells by diluting the red blood cells and washing them of the cryopreservative. Again, the system preferably adjusts the delivery rate of a dilution solution so as to prevent osmolarity shock of the red blood cells during the recovery phase. The recovered red blood cells may be suspended in a preservation solution to further increase their shelf-life following the recovery phase.Type: GrantFiled: December 7, 1998Date of Patent: July 31, 2001Assignee: Haemonetics CorporationInventor: Etienne Pages
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Patent number: 6241943Abstract: Use of a solution comprising glucose for peritoneal dialysis, in which the glucose portion is sterilised separately from the remaining components at a high glucose concentration above about 20% and mixed after sterilisation, substantially according to WO 93/09820. The solution has a reduced formation of advanced glycosylation end products and the use is indicated for diabetic uremic patients.Type: GrantFiled: December 1, 1998Date of Patent: June 5, 2001Assignee: Gambro ABInventors: Anders Wieslander, Gunita Forsbäck, Torbjörn Linden, Reinhold Deppisch, Thomas Henle, Anne Dawnay
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Patent number: 6197936Abstract: To provide a plastic vessel containing an albumin preparation which completely restrains formation of thermally denatured albumin, a plastic molded member in a cylindrical shape is extruded in a molten state into opened dies, one end of which is closed in the dies, and a vessel is molded by blowing a compressed gas into the molded member in the dies or by bringing inner portions of the dies into a vacuum state. While the vessel is still disposed in the dies, an albumin preparation is introduced from an opening portion into an inner portion of the vessel and, therefore, the albumin preparation can be filled into the vessel in a sterilized state without being brought into contact with the atmosphere. Then, an opening portion of the vessel filled with the albumin preparation is hermetically sealed at an internal temperature of the opening portion of about 40° to 70° C. Thus formation of thermally denatured albumin can be completely restrained.Type: GrantFiled: October 20, 1999Date of Patent: March 6, 2001Assignee: Nissho CorporationInventors: Minoru Sano, Yoshihisa Hama, Toshiya Kai, Masakazu Mameta
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Patent number: 6136267Abstract: A fuel ignition arrester system that has a feedback control to maintain the fuel/air mixture in the ullage of a fuel tank above the flammability range. The system uses a photoelectric detector to signal when the fuel/air mixture concentration falls or rises to a predetermined concentration value. The predetermined value is selected to be higher than the upper limit of the flammability range so that the fuel/air mixture is maintained above the range and, thus, incombustible. A fuel pump and piping system with nozzles is arranged to inject fuel into the ullage when the concentration falls to the predetermined value and to stop injecting fuel when the concentration rises to the predetermined value. A flammability detection system includes the detector and a controller that produces an annunciating signal when the fuel/air mixture concentration is equal to or between the upper and lower limits of the flammability range.Type: GrantFiled: August 24, 1998Date of Patent: October 24, 2000Assignee: Bergman Consulting EngineersInventor: Jacob Bergman
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Patent number: 6083459Abstract: The present invention provides a compact-sized reservoir with small power consumption. It suppresses possible oxidation of articles and growths of putrefactious aerobic organisms such as bacteria, fungi and the like, by storing the articles under an atmosphere of reduced oxygen concentration created by an oxygen pump device which makes use of an oxygen ion-conductive film. In a case of storing foods, the disclosed reservoir makes their long-term storing possible. The reservoir in accordance with the present invention uses an oxygen pump device provided with an oxygen ion-conductive electrolyte film and a pair of electrodes formed on the both surfaces thereof.Type: GrantFiled: June 29, 1998Date of Patent: July 4, 2000Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Yuji Mukai, Yasuhito Takahashi
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Patent number: 6060021Abstract: Trichlorosilane for producing polycrystal silicon and tetrachlorosilane for producing trichlorosilane are storaged under hydrogen gas as a sealing gas. High-purity polycrystal silicon is provided.Type: GrantFiled: May 1, 1998Date of Patent: May 9, 2000Assignee: Tokuyama CorporationInventor: Hiroyuki Oda
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Patent number: 5972225Abstract: A novel process for selectively removing endotoxin from an aqueous solution containing bulk, iodinated, non-ionic contrast media and endotoxin by passing the solution through an activated carbon filter. The process can be economically practiced on a factory scale.Type: GrantFiled: May 7, 1997Date of Patent: October 26, 1999Assignee: Cook Imaging CorporationInventors: Lee Karras, Barry Graham
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Patent number: 5968451Abstract: A process for sterilizing a container holding a fluid diet, the container having a long and slender mouth and being filled with the fluid diet and sealed; the process includes the steps of filling the container with the fluid diet in a heated state, sealing the container at the mouth thereof, and thereafter turning the container with its mouth side down to immerse only the mouth and the vicinity thereof in a hot-water bath for a period of time sufficient to achieve sterilization. An apparatus for carrying out the process includes a bucket conveyor, a feed conveyor, a bucket and a bath. The process and apparatus can well sterilize containers holding a fluid diet and having a long and slender mouth. The process and apparatus can well sterilize containers holding a fluid diet and having a long and slender mouth.Type: GrantFiled: June 12, 1997Date of Patent: October 19, 1999Assignee: Morinaga & Co., Ltd.Inventors: Tsutomu Iwamoto, Yoshinori Ohtsuka, Nobuo Kiriu, Norihito Watanabe
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Patent number: 5955371Abstract: A blood collection device comprising formed additive particles. The additive particles are an improvement over available additive formulations that are powder blended in that the components of the additive particles of the present invention are in each formed particle. The formed additive particles comprise a fluoride salt and an ethylenediaminetetraacetate salt or a heparin salt to consistently minimize glycolysis and coagulation of a blood specimen with low hemolysis.Type: GrantFiled: November 13, 1997Date of Patent: September 21, 1999Assignee: Becton Dickinson and CompanyInventors: Tatsuhiko Ikeda, Ajit N. Dastane, Robert Losada
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Patent number: 5939021Abstract: A homogeneous method of measuring chemical binding relies on resonant, or "amplified," optical extinction (light scattering plus absorption) from a defined, specific class of colloidal particles wherein the real term n of the complex refractive index n-ik approaches zero while the imaginary term k approaches .sqroot.2. Chemical binding partners are coated onto the particles, which either aggregate or disperse during the binding reaction, causing an optical extinction change at one wavelength that is quantitatively related to the number of single colloidal particles and another at a second wavelength that is quantitatively related to the number of doublet colloidal particles.Type: GrantFiled: January 23, 1997Date of Patent: August 17, 1999Inventors: W. Peter Hansen, Petra B. Krauledat
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Patent number: 5882588Abstract: In the process for the ozone treatment of hot water in the hot water supply system of a building for the purpose of disinfection of the water, the hot water is led into a treatment tank (3). Here the pressure is reduced to a level below that in the pipes of the hot water supply system, an ozone-containing gas being continually introduced into the water, which gas passes through the water in the form of bubbles, the ozone being given up to the water. The remaining gas subsequently undergoes transition to a gaseous state in the upper part of the tank, from which the gas is drawn off. The treated water is then fed into the hot water supply system of the building, the pressure being restored by means of at least one pump to the level of the operating pressure within the hot water supply system. The method can be used to remove harmful micro-organisms such as legionella pneumophila from hot water systems without raising the temperature to around 70.degree. C.Type: GrantFiled: July 18, 1995Date of Patent: March 16, 1999Assignee: CarbagasInventor: Fabrice Laberge
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Patent number: 5876663Abstract: A method and apparatus are disclosed for sterilization of liquids using a steady-stage glow discharge apparatus, at one atmosphere.Type: GrantFiled: November 12, 1996Date of Patent: March 2, 1999Assignee: The University of Tennessee Research CorporationInventor: Mounir Laroussi
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Patent number: 5772960Abstract: Containers for medical use comprising a storage portion formed of a soft polyvinyl chloride resin containing a vinyl chloride resin and diundecyl pthalate (DUP) as a plasticizer wherein the sheet exhibits an oxygen permeability of about 9.0.times.10.sup.-10 to 22.0.times.10.sup.-10 cc.cm/cm2.sec.cmHg/22.degree. C. and a carbon dioxide permeability of about 6.0.times.10.sup.-9 to 19.0.times.10.sup.-9 cc.cm/cm2.sec.cmHg/22.degree. C. The containers are suitable for the storage of blood, especially the cellular components of blood. The invention also provides processes for making such containers as well as methods for storing blood cells using such containers.Type: GrantFiled: December 3, 1996Date of Patent: June 30, 1998Assignee: JMS Co., Ltd.Inventors: Takushi Ito, Kouji Suzuki, Norihiko Kobayashi
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Patent number: 5746973Abstract: Odorant depletion is reduced by passivating the internal surface of LP-gas transportation and storage vessels by the addition of passivating agents comprising mixtures of corrosion inhibitors such as phosphate esters, fatty amines, poly amides, imidazolines, poly imidazolines, quaternary amines, poly quats, dimer acids, trimer acids, polymeric acids, ethoxylated fatty amines, ethoxylated polyamides, ethoxylated alcohols and mixtures thereof in one or more solvents. In a preferred embodiment, the passivating agents contain one or more phosphate esters defined by the equation:?R--X--?C.sub.m H.sub.2m O).sub.n !.sub.k --PO(OH).sub.Type: GrantFiled: July 10, 1996Date of Patent: May 5, 1998Inventor: Ali Naraghi
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Patent number: 5721024Abstract: Improved flexible film and tubing for medical products manufactured from a PVC compound, comprising an amount of ultra high molecular weight (UHMW) PVC resin having an inherent viscosity ranging from about 1.25 to about 2.00, most preferably about 1.71, and about 43 to about 57 percent by weight of a medically acceptable plasticizer, most preferably about 53 percent, such as tri (2-ethylhexyl) trimellitate (TOTM).Type: GrantFiled: June 7, 1995Date of Patent: February 24, 1998Assignee: Pall CorporationInventors: Raleigh A. Carmen, Ronald H. Bauman
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Patent number: 5693252Abstract: A method of preparing chlorine dioxide in a non-aqueous liquid is disclosed. An aqueous solution of chlorine dioxide is mixed and agitated with a non-aqueous liquid. The chlorine dioxide is extracted into the non-aqueous liquid. In a preferred embodiment, an aqueous chlorite solution is added to a quantity of non-aqueous liquid. Acid is added to the aqueous phase to generate chlorine dioxide. The phases are vigorously agitated to extract the chlorine dioxide into the non-aqueous phase. High concentrations of very pure chlorine dioxide are obtainable. In another preferred embodiment, chlorine is prepared in a non-aqueous liquid and is mixed and agitated with an aqueous chlorite solution. Separation of the aqueous and non-aqueous phases provides pure solutions of chlorine dioxide in the non-aqueous liquid. Very pure aqueous solutions of chlorine dioxide are prepared by mixing and agitating non-aqueous solutions of chlorine dioxide with water.Type: GrantFiled: January 17, 1996Date of Patent: December 2, 1997Assignee: Rio Linda Chemical Co., Inc.Inventor: Anthony R. Pitochelli
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Patent number: 5679287Abstract: A method for storing atmosphere sensitive product includes providing an atmosphere surrounding the product which contains at least about 5% heptafluoropropane, preferably at least about 20% heptafluoropropane. The stored products include food, pharmaceutical and chemical products, and mechanical and electrical equipment. In a particular aspect, the method includes storing the product in a closed container and providing in the headspace of the container an atmosphere containing heptafluoropropane.Type: GrantFiled: April 28, 1995Date of Patent: October 21, 1997Assignee: Great Lakes Chemical CorporationInventors: Charles J. Mazac, John S. Rubacha
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Patent number: 5536469Abstract: System employing a sterile medical solution containing glucose or glucose polymers, for example nutritional solutions or solutions for peritoneal dialysis, whereby the majority of the solution is packed in a first package, while the glucose or the glucose polymers are separately packed in a second package, whereafter the two packages are heat sterilized. The content of the glucose or glucose polymers in the second package is maintained above 10% by weight, preferably above 20% by weight and most preferably in the order of 40% by weight in order to reduce or totally eliminate the breakdown of glucose. The medical solution after sterilization, mixing and diluting to 1.5% glucose content has an absorbency caused by breakdown products from glucose at 228 nm less than 0.35 and preferably in the order of 0.20 or lower. The medical solution is also defined in that after sterilization, mixing and dilution to 1.Type: GrantFiled: May 16, 1994Date of Patent: July 16, 1996Assignee: Gambro ABInventors: Sven Jonsson, Per Kjellstrand, Evi Martinson, Anders Wieslander, Eva Svensson, Anders Andren
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Patent number: 5523051Abstract: Fresh urine to be tested eventually for detection of abuse-type drugs is preserved at room temperature for as long as six months by adding to the urine a small amount of a methanol solution of methyl and propyl parahydroxybenzoic acids.Type: GrantFiled: February 1, 1991Date of Patent: June 4, 1996Inventor: Jacob J. Gibson
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Patent number: 5489281Abstract: A process for delivering a biocide to a container comprising admitting a biocide delivery device through an exit port of a urine container where the device is sized for passage through the exit port is disclosed.Type: GrantFiled: January 8, 1992Date of Patent: February 6, 1996Assignee: Alza CorporationInventors: Tyler Watanabe, Su I. Yum, Eun S. Lee, Ivan W. Chin
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Patent number: 5433920Abstract: An ultraviolet (I/V) sterilization system for food cartons is disclosed. An elongated UV lamp is mounted in a housing. A parabolic cylinder reflector is mounted in the housing with the focus of the reflector coinciding with the axis of the arc in the UV lamp. The shape of the parabolic reflector directs radiation from the lamp into cartons positioned on a conveyor below the lamp. The axis of the arc is parallel to the direction of movement of the cartons on the conveyor. The front surface of the reflector also absorbs heat from the lamp and heat is removed from the reflector by circulating air over the back surface of the reflector.Type: GrantFiled: March 17, 1994Date of Patent: July 18, 1995Assignee: Tetra Laval Holdings & Finance SAInventors: Charles E. Sizer, Terry D. Erickson, Terrence E. Manley
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Patent number: 5433921Abstract: Process and installation for supplying at least one pure active gas to at least one utilization station (P.sub.i) in a first building (A) at a utilization site. It comprises the steps of providing, at the utilization site, a second safety building (B) at a distance from the first building (A), providing at least one source (2; 7; 10) of said gas in the second building (B), and transferring, by at least one safety conduit (C) of high cleanliness, the gas, at a low pressure, to the utilization station (P.sub.i). There is also taught the step of purifying (4; 11) the gas in the second building (B) before transfer to the conduit (C). The pure gas is prepared in situ (2, 4; 10, 11) in the second building (B). There can alternatively be provided, adjacent to the second building (B), at least one source of vector gas (1), with mixing in controlled fashion (6; 9), in the second building (B), the pure active gas with the vector gas before transfer of the mixture to the conduit (C).Type: GrantFiled: February 28, 1994Date of Patent: July 18, 1995Assignee: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventor: Yasuo Sato
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Patent number: 5429801Abstract: The features of a surgical slush machine are augmented by a separate warming basin for surgical liquid to thereby permit simultaneous availability of the warmed liquid and surgical slush. The slush cooling basin is disposed adjacent the warming basin, and a common sterile drape is disposed over and contoured to both basins to provide separate sterile receptacles in the drape for the liquid and slush. Basin centering indicia on the drape facilitate deployment of the drape relative to the basins. Cooling and heating of the respective basins are effected independently with individual power controls.Type: GrantFiled: April 7, 1994Date of Patent: July 4, 1995Assignee: O.R. Solutions, Inc.Inventors: Durward I. Faries, Jr., Bruce R. Heymann
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Patent number: 5417675Abstract: The invention disclosed and claimed an apparatus that relates to a delivery system comprising a biocide, with the delivery system designed and shaped for passages through the exit port of a urine container into the container. The invention disclosed and claim pertains also to a method of preventing infection in a patient by using the apparatus connected to a patient through a catheter.Type: GrantFiled: January 8, 1992Date of Patent: May 23, 1995Assignee: Alza CorporationInventors: Tyler Watanabe, Su I. Yum, Fun S. Lee, Ivan W. Chin
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Patent number: 5417676Abstract: An apparatus is disclosed comprising in combination (1) a container for receiving a fluid, and having an exit port, and (2) a delivery system designed for passage through the exit port into the container for releasing a biocide inside the container.Type: GrantFiled: January 8, 1992Date of Patent: May 23, 1995Assignee: Alza CorporationInventors: Tyler Watanabe, Su I. Yum, Eun S. Lee, Ivan W. Chin
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Patent number: 5326542Abstract: An ultraviolet (UV) sterilization system for food cartons is disclosed. An elongated UV lamp is mounted in a housing. A parabolic cylinder reflector is mounted in the housing with the focus of the reflector coinciding with the axis of the arc in the UV lamp. The shape of the parabolic reflector directs radiation from the lamp into cartons positioned on a conveyor below the lamp. The axis of the arc is parallel to the direction of movement of the cartons on the conveyor. The front surface of the reflector also absorbs heat from the lamp and heat is removed from the reflector by circulating air over the back surface of the reflector.Type: GrantFiled: October 1, 1992Date of Patent: July 5, 1994Assignee: Tetra Laval Holdings & Finance S.A.Inventors: Charles E. Sizer, Terry D. Erickson, Terrence F. Manley
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Patent number: 5288459Abstract: A process is disclosed wherein whole blood or a blood fraction, such as platelets or leukocytes are stored within a modulated electrical field, such as a capacitive field, to extend the shelf life of the blood or fraction.Type: GrantFiled: June 8, 1993Date of Patent: February 22, 1994Assignee: Biolectron, Inc.Inventor: Joseph L. Lawrence
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Patent number: 5269946Abstract: Systems and methods of collecting blood cells use a first container connected to at least three transfer containers. A filtration system is provided with one transfer container, which ultimately serves as the storage container for red blood cells free of white blood cells. The two other transfer containers are connected to each other, one of which is empty and one of which contains and additive solution for storage of red blood cells. The empty transfer container is used for storage of platelet concentrate, while the container that originally contained the additive solution is ultimately used to store the platelet-poor plasma component. A portion of the additive solution may be separately passed through the filtration system after filtration of the red cells to flush additional red blood cells from the filtration device.Type: GrantFiled: May 22, 1991Date of Patent: December 14, 1993Assignee: Baxter Healthcare CorporationInventors: Richard Goldhaber, Daniel F. Bischof
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Patent number: 5217627Abstract: A system for collecting and processing donated blood comprises a first porous medium interposed between a blood collection bag and a satellite bag and a second porous medium interposed between the blood collection bag and another satellite bag. The porous media are leucocyte depletion media. The system may also include one or more of the following: a red cell barrier medium, a separation medium, a gas inlet, and a gas outlet. The system can be used to centrifuge whole blood into one or more components, and includes a means for protecting the system during centrifugation.Type: GrantFiled: November 6, 1991Date of Patent: June 8, 1993Assignee: Pall CorporationInventors: David B. Pall, Thomas C. Gsell, Vlado I. Matkovich, Thomas Bormann
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Patent number: 5217618Abstract: A plasma purification treatment which removes disease ailment causing constituents in the plasma of a patient suffering from diseases caused by those ailment causing constituents in this patient's plasma by plasma exchange made by sampling of plasma from the patient and returning the plasma sampled from the patient and purified by removing the ailment causing constituents to the patient; sampling an appropriate volume of plasma within 12% of the patient's whole circulating blood at the first time and gradually increased volume from the second time on until it reaches a predetermined target volume of plasma exchange, returning the sampled plasma at the previous time and purified.Type: GrantFiled: August 26, 1991Date of Patent: June 8, 1993Assignee: Terumo Kabushiki KaishaInventor: Masahide Murakoshi
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Patent number: RE35804Abstract: Systems and methods of collecting blood cells, substantially free of undesired matter, use a first container, that forms a part of a blood collection system, to initially collect a quantity of blood cells. A filtration system is then attached to the first container. The filtration system includes a second container, a first fluid path that leads to the second container through a filtration device, and a second fluid path that leads to the second container bypassing the filtration device. The blood cells are conveyed from the first container through the first fluid path and filtration device and into the second container to separate the undesired matter from the blood cells. The blood cells, now substantially free of the undesired matter, are then conveyed from the second container through the second fluid path, bypassing the filtration device, and back into the first container. The filtration system is then detached from the blood collection system.Type: GrantFiled: March 4, 1993Date of Patent: May 26, 1998Assignee: Baxter International Inc.Inventor: Mary A. Stewart