Abstract: Systems and methods for collecting blood substantially free of undesired matter assure that accurate crossmatching and typing of cellular blood components can be done prior to transfusion, even though the cellular components are collected and stored in different containers. The blood containing the undesired matter is collected in a blood collection container. The blood collection container includes a tube that is sealed for retaining samples of the collected blood for later analysis. The collected blood is conveyed out of the blood collection container for removal of undesired matter. The blood substantially free of the undesired matter is collected in a separate transfer container for storage. The distal end of the sealed tube containing the blood samples is attached to the transfer container, while the other end of the sealed tube is disconnected from the original blood collection container.

Abstract: The invention discloses a method for treating blood comprising (a) centrifuging blood and (b) passing a supernatant layer of the centrifuged blood through a porous medium until red blood cells block the porous medium.

Abstract: The present invention relates to microbiocidal composition and methods for the preparation and use of of such compositions. Properly used in accordance with the present invention, these microbiocidal compositions are effective in killing or inhibiting a wide variety of harmful, destructive or offensive microorganisms including viruses, bacteria, yeasts, algae and molds. The microbiocidal compositions of the present invention are suitable for use with conventional detergents to provide microbiocidal cleansing agents. The microbiocidal compositions can also be mixed with a liquid to provide an effective disinfectant. The microbiocidal additive can be incorporated into plastic materials and various synthetic fibers thereby imparting microbiocidal activity to the plastic materials or fibers.

Abstract: Systems and methods of collecting blood cells use a first container connected to initially collect blood. A filtration system is provided that uses two flow paths, the first being a dual purpose path that is initially used to convey plasma and platelets to a pair of transfer/storage containers. A second flow path leads to a temporary transfer container through a filtration device. The dual purpose fluid path is next used to convey blood cells, now substantially free of undesired matter, from the temporary storage container to a storage container. The filtration system is then detached from the blood collection system.

Abstract: This invention relates to an anti-freeze separator assembly connected to a piece of equipment in outdoor freezing conditions in order to take a fluid, such as water, and treat same for subsequent disposal without freezing. The anti-freeze separator assembly includes 1) a main container housing; 2) a material retainer member mounted within the main container housing to receive and hold a treatment chemical therein; 3) an enclosure cap assembly releasably mounted on the main container housing; 4) a main fluid inlet assembly connected to the main container housing to transfer a fluid to be treated therein; and 5) a main discharge assembly connected to the main container housing to transfer a treat fluid therefrom. The main discharge assembly includes a discharge pipe member connected to a transfer pipe assembly with a diaphragm valve assembly therebetween.

Abstract: Method for storing, preserving and transporting concentrates of human platelets under blood bank conditions prior to transfusion by compressing plastic walled platelet bags with the use of a grid to permit gas circulation to the bag with the bag positioned for storage in a desired position. A grid aids in storing and preserving platelets and has a rigid body with a substantial open area configured to substantially compress a side of a plastic walled platelet bag to form a substantially uniform layer of fluid in the bag to maximize gas transfer capacity and permit long storage life at atmospheric conditions without the need for conventional agitation of the bag.

Abstract: Systems and methods of collecting blood cells, substantially free of undesired matter, use a first container, that forms a part of a blood collection system, to initially collect a quantity of blood cells. A filtration system is then attached to the first container. The filtration system includes a second container, a first fluid path that leads to the second container through a filtration device, and a second fluid path that leads to the second container bypassing the filtration device. The blood cells are conveyed from the first container through the first fluid path and filtration device and into the second container to separate the undesired matter from the blood cells. The blood cells, now substantially free of the undesired matter, are then conveyed from the second container through the second fluid path, bypassing the filtration device, and back into the first container. The filtration system is then detached from the blood collection system.

Abstract: An article of manufacture comprising a blood-collection tube containing an acid such as citric acid in an amount effective to adjust the pH of the blood to be collected in the tube to a level between 5.0 to 7.0. The blood-collection tube may also contain NaF in an amount to produce a concentration thereof between 0.1 to 0.5 mg/ml of the blood.

Abstract: A multiple blood bag system is disclosed having at least two blood bags and conduit means providing sealed flow communication between the bags and a filtering means integrally disposed between two of the bags for removing platelets and white cells from a red cell concentrate in the blood bag system. In the method of the invention a red cell concentrate is provided in one of the blood bags of the above system and an additive solution is mixed therewith. The mixture of the red cell concentrate and additive solution is passed through the filtering means from one of the bags to another.

Abstract: Closed filtering system for relatively fast and efficient removal of white blood cells from a red blood cell mixture. System comprises at least two blood bags in closed communication with each other via an intermediate filter assembly comprising a housing containing continuous filtering fiber. A preferred housing is tapered and the fiber preferably has a generally Y-shaped cross sectional area and it is adapted to permit substantial removal of white blood cells from a red blood cell mixture with minimal red blood cell hemolysis when the mixture is diluted with preservative solution and passed from one bag to the other at a relatively high flow rate. Filtration is completed within 24 hours, preferably within 6 hours, of whole blood donation.

Abstract: Closed filtering system for relatively fast and efficient removal of white blood cells from a red blood cell mixture. System comprises at least two blood bags in closed communication with each other via an intermediate filter assembly comprising a housing containing continuous filtering fiber. A preferred housing is tapered and the fiber preferably has a generally Y-shaped cross sectional area and it is adapted to permit substantial removal of white blood cells from a red blood cell mixture with minimal red blood cell hemolysis when the mixture is diluted with perservative solution and passed from one bag to the other at a relatively high flow rate. Filtration is completed within 24 hours, preferably within 6 hours, of whole blood donation.

Abstract: A plasma bag support rack is described which is useful for suspending frozen plasma bags in a water bath. The support rack includes a main cross member that has two pairs of vertically oriented hooks projecting downward. The cross member has rubber coated ends to prevent slippage during thawing. Frozen plasma bags are suspended by the support rack hooks from the support holes at the top of the bags. The rubber coated cross member ends are then seated on the top edge of a water bath during plasma bag thawing. The support rack holds the entry ports of frozen plasma bags out of the bacteria contaminated water which is commonly found in plasma thawing water baths. This support rack provides a means for safe and rapid thawing of frozen plasma bags.

Abstract: A container for storing blood for a long period of time to keep the quality of the blood in good condition, is formed of a laminated film type bag composed of at least one thermoplastic resin film layer and at least one addition polymerization type silicone rubber film layer, the surface of the laminated film which comes in direct contact with the blood is made of the addition polymerization type silicone rubber film layer; the thermoplastic resin film layer has a permeability to carbon dioxide gas of 6,000 to 70,000 ml/m.sup.2.24 hr. for a thickness of 0.025 mm at 25.degree. C.; and the whole laminated film type bag has a permeability to carbon dioxide of 5,000 ml/m.sup.2.24 hr.atm at 25.degree. C. for storing whole blood and packaged red blood cells, and a permeability to carbon dioxide of 2,000 to 9,000 ml/m.sup.2.24 hr. atm at 25.degree. C. for storing platelet preparations.

Abstract: This disclosure relates to a blood processing and preservation system. Apparatus of the system comprises a primary collection bag, a blood collection tube connected to the bag and adapted to draw a unit of blood from a person and feed the blood into the bag, and a harness connected to the bag for conducting solutions and blood components into and out of the bag. The harness includes a first tube for removing at least one blood component from the bag while retaining another component, a second tube for moving a cryoprotective solution into and out of the bag, a third tube for conducting a wash solution into and out of the bag, and identification on the bag.

Abstract: There is described a method of inhibiting glycolysis in blood samples by adding an acid to the blood sample to adjust pH of the blood to a level between 5.0 and 7.0.Collected blood samples undergo glycolysis during storage due to progress of the reaction with glycolytic enzymes with a result that glucose is reduced and lactic acid and pyruvic acid formed by the glycolysis is increased. According to the method of the invention, the glycolysis as mentioned above can be inhibited simply by adjusting pH of the blood sample so that accurate determination of the above-mentioned components are feasible. The preferred acids are citric acid, malonic acid and maleic acid. Addition of citric acid to produce a level between 1.0 and 5.0 mg/ml (blood) is especially preferable. In the method of the invention, further addition of a fluoride compound, preferably NaF, improves the glycolysis-inhibiting action.

Abstract: A microtiter plate for blood typing consisting of a flat-bottomed plate of rigid transparent polystyrene having a plurality of wells, the polystyrene being surface treated by a corona and/or plasma method of applying high power electric energy at high frequency resulting in a permanently measurable negative ion-charge at the surface of the wells, and layers of substantially pure antiserums dried on the wells without any binder from a suspension or solution of the antiserums and tightly but releasably bound to the polystryene.

Abstract: A container body is formed of a polymer material and contains coloring matter effective to render the body substantially opaque to electromagnetic radiation having a wave length of about 5 to about 600 nm and translucent or semi-transparent to electromagnetic radiation having a wave length of about 600 to about 800 nm. The container permits storage and transport of photosensitive fluids, for example, body fluids for test purposes which contain bilirubin and other photo-degradable substances, but at the same time the contents of the container body are apparent from visual inspection.

Abstract: A multiple blood bag system is disclosed having at least two blood bags and conduit means providing sealed flow communication between the bags and a filtering means integrally disposed between two of the bags for removing platelets and white cells from a red cell concentrate in the blood bag system. In the method of the invention a red cell concentrate is provided in one of the blood bags of the above system and an additive solution is mixed therewith. The mixture of the red cell concentrate and additive solution is passed through the filtering means from one of the bags to another.

Abstract: A process for preventing odor-fading of liquefied petroleum gas odorized with organosulfur compounds wherein the gas is stored in containers having new or recently cleaned interior surfaces, such surfaces having been pretreated with benzotriazole, tolyl triazole, mercaptobenzothiazole, benzothiazyl disulfide or mixtures thereof.

Abstract: A composition for protection of the liquid surface from heat- and mass-trfer, for example from evaporation, contains a polymer limitedly swelling in the protected liquid or a mixture of said polymer with a neutral filler having a density lower than the density of the protected liquid.A method for protection of the liquid surface from heat- and mass-transfer comprising application of said composition on the surface of a liquid, for example petroleum, in an amount of from 0.1 to 2 kg per m.sup.2. Upon contacting of the polymer with the liquid the polymer rapidly swells and forms a continuous gel-like covering which hinders the heat- and mass-transfer on the liquid surface.

Abstract: A process of using a thermally insulating board, made of a homogeneous mixture of expanded perlite particles and cellulosic and/or mineral and/or ceramic fibers, bonded together, comprising placing on the surface of a molten steel mass, in direct contact with the surface, so as to cover substantially all the surface. According to a preferred embodiment, the board consists of 51 to 80% by weight of expanded perlite particles, 15 to 39% by weight of cellulosic and/or mineral fibers and 5 to 10% by weight of binder.

Abstract: The stability of bicarbonate dialysate is maintained over a prolonged period by maintaining a blanket of CO.sub.2 at atmospheric pressure over the solution in an air-tight storage tank having a non-leaching interior. The CO.sub.2 blanket is kept at atmospheric pressure in the storage tank by use of a negative pressure regulator connected to the CO.sub.2 gas cylinder. HCO.sub.3 in the stored dialysate remained stable for as long as thirty days.

Abstract: A technique and apparatus for thawing a frozen blood plasma unit while maintaining the unit in a dry condition includes a water bath and a special holder which supports a thin plastic bag in which the plasma unit is contained. The holder maintains the bag and the plasma unit submerged in a manner which affords substantial thermal contact between the plasma unit and the water bath.

Abstract: Containers used for storing and dispensing liquids for medical applications include a closure, and medical connection device include cooperating connector members. An article of manufacture and a method are provided where a plastic outer closure is applied over container closures or over connection devices. The application of the plastic outer closure exerts an antibacterial effect in the juncture area defined by the interface of the outer closure and the container inner closure and neck, or defined by the interface of the outer closure and the connection site of the connector members. The outer closure is of a type of plastic that releases an antibacterial agent, which exerts an antibacterial effect in the juncture area.

Abstract: A method and apparatus of processing biological fluids by adding or removing preservatives or simply removing water comprises providing a bag of semi-permeable membrane which contains the biological fluid and bathing the bag with dialysate having controlled osmolality. The preservative or water can thus be removed or added to the bag directly through the semi-permeable membrane by controlling the osmolality of the dialysate without exposing the biological fluid to contaminants. In the case of whole or components of blood, the blood or blood components can be collected in the bag, processed for preservation, and prepared for use then administered, all in the same bag.

Abstract: Disclosed are cell-free, stable, aqueous blood gas controls containing a proteinaceous foaming agent. The addition of foaming agent to the blood gas control permits generation of a gas impermeable foam within the head space of a sealed ampule in which the control is packaged. Upon agitation of the ampule prior to opening, the foam thus generated effectively isolates the control fluid from the ambient environment, thereby maintaining the concentration of gases dissolved within the fluid at their assigned values.

Abstract: A drain cleaner package which reduces the hazards of handling a caustic material, such as sulfuric acid, or an aqueous alkali metal hydroxide solution in a container by providing a layer of immiscible liquid in the container above the caustic material. In a preferred embodiment, the container is a bottle with a narrowed neck.

Abstract: A chemical seal for isolating the liquid phase of a contained liquid from the vapor phase present in the container headspace comprises a chemically impregnated gel formed by mixing a biopolymer gel, a high molecular weight polymer and chemical impregnants with water to form a gel-forming aqueous solution which is applied to the surface of the contained liquid and allowed to solidify thereby forming a mechanically stable, chemically impregnated gel seal in intimate contact with the contained liquid.

Abstract: A resin purger which reliably determines when purging is completed and prnts humid air from re-entering the purged material. A sealed container has an inlet valve attached to a source of inert purge gas and an outlet valve. A diffuser is connected to the outlet valve to screen the exit gas from the container. A probe sensor detects the amount of oxygen in the exit gas and indicates when purging is complete.

Abstract: A storage tank for storing of liquid food products partially processed before final processing. The tank is constructed with smooth germ-free internal surfaces to avoid recesses in which the stored food product or disinfecting fluids can be entrained and contaminate the tank and food product therein. A dispersion device in a conical top of the storage tank homogenizes the food product to be stored when introduced in the tank. The same dispersion device disperses treatment liquids introduced into the tank to effect dispersion onto all the inner surfaces for treatment thereof.

Abstract: A short length of copper pipe for being dropped into a water tank, so to retard against the growth of moss in the water; and means in a modified design of the device for forcing the water to circulate through the pipe in order to increase the efficiency thereof.

Abstract: An apparatus for storing molten materials comprising a storage tank; inlet and outlet means associated with the storage tank to provide access and egress for the molten material; steam supply means for providing steam to the storage tank; vapor removal means providing for exit of vapor from the vapor space of the storage tank; a liquid powered eductor in fluid communication with the vapor removal means acting to urge vapors from the storage tank through the vapor removal means; and a liquid supply means associated with the eductor to provide liquid to operate the eductor, the amount of liquid supplied being controlled in response to the vapor pressure within the storage tank.An improved method for storing molten materials is also disclosed.

Abstract: It has been found that the shelf life of stored whole blood may be doubled by adding a buffer which maintains a desired pH level. However, this buffer causes the generation of CO.sub.2 which, if not removed at a controlled rate, causes the pH value of the blood to decrease, which shortens the useful life of the blood. This invention provides a blood storage bag which permits the CO.sub.2 to be diffused out at a controlled rate into the atmosphere, thereby maintaining the desired pH value while providing a bag strong enough to permit handling thereof.

Abstract: A waste treatment composition and process wherein a salt of lignosulfonic acid and a foam-forming surfactant system are applied to nitrogenous waste material.

Abstract: This disclosure relates to a blood processing and preservation system. Apparatus of the system comprises a primary collection bag, a blood collection tube connected to the bag and adapted to draw a unit of blood from a person and feed the blood into the bag, and a harness connected to the bag for conducting solutions and blood components into and out of the bag. The harness includes a first tube for removing at least one blood component from the bag while retaining another component, a second tube for moving a cryoprotective solution into and out of the bag, a third tube for conducting a wash solution into and out of the bag, and identification on the bag.