Abstract: The present invention relates to a device for manually metering liquids, for example a pipette or a metering button. The device comprises a joint forming a seal between a hollow cylinder and a piston housed inside the cylinder, the piston being moved vertically so as to suck in or expel the liquid. During the metering operation, the joint remains fixed with respect to the movement of the piston and comprises parts formed by portions having dedicated geometric and mechanical characteristics which make it possible to locally optimize the functions of sliding, sealing and fastening in the cylinder.

Abstract: A system for titrating liquids, with a syringe or tip, comprising a holding device and at least one tag and a metering equipment, comprising an additional holding device for holding the syringe or tip on the holding device, a reading device for reading the tag of the syringe or tip held by the additional holding device, a driving device having a motor, which is detachably coupled with a plunger of the syringe when the same is held by the additional holding device, or which is coupled with a plunger which is arranged in a cylinder which is coupled with the tip via a fluid conduit, when the same is held by the additional holding device, an operating device for operating the metering equipment and a control device, connected with the operating device, the reading device and the driving device, which controls the movement of the plunger depending of the tag of the inserted syringe or tip.

Abstract: Systems and apparatus for mixing, cooling, and distributing multiphase fluid mixtures within a reactor, wherein reactor internal apparatus of the present invention provides not only improved fluid mixing and distribution to each underlying catalyst bed surface, but also offers other advantages including: decreased mixing tray height; easier maintenance, assembly and disassembly; and decreased amounts of fabrication material. In an embodiment, fluid may be evenly distributed to a catalyst bed from a fluid distribution unit comprising a nozzle tray including a plurality of nozzles, wherein the nozzles include at least one liquid inlet disposed tangentially to an inner surface of the nozzle.

Abstract: A method of pipetting comprises (a) providing a pipette tip holder having a plurality of segregated compartments and a tip support member for supporting a plurality of pipette tips in the pipette tip holder, the tip support member configured to support a single pipette in tip each segregated compartment; (b providing a plurality of pipette tips in the tip support member; (c) removing a first pipette tip from a first segregated compartment; (d) using the first pipette tip to complete a pipetting operation and placing the first pipette tip into a segregated compartment that has not contained a used pipette tip; (e) subsequently removing the first pipette tip from the segregated compartment and using the first pipette tip to complete another pipetting operation; and, (f) replacing the first pipette tip into the pipette tip holder, whereby the first pipette tip, when placed in the segregated compartment, is segregated in the pipette tip holder to reduce the possibility of a fluid from the first pipette tip contac

Abstract: Systems and apparatus for mixing, cooling, and distributing multiphase fluid mixtures within a reactor, wherein reactor internal apparatus of the present invention provides not only improved fluid mixing and distribution to each underlying catalyst bed surface, but also offers other advantages including: decreased mixing tray height; easier maintenance, assembly and disassembly; and decreased amounts of fabrication material. In an embodiment, fluid may be evenly distributed to a catalyst bed from a fluid distribution unit comprising a nozzle tray including a plurality of nozzles, wherein the nozzles include at least one liquid inlet disposed tangentially to an inner surface of the nozzle.

Abstract: The invention provides ways to determine the impact of diluting a solution wherein the diluting may be carried out for any of a variety of purposes. In one embodiment, the method enables accurate volume dispensation calculations independent of meniscus shape. In another embodiment, the method enables accurate determination of plate washing efficiency. In yet another embodiment, the method enables the accurate determination of dilution ratio over a plurality of dilution steps. The methods described may be carried out using one or more systems arranged to perform the steps. A kit of the invention includes instructions for carrying out the steps of the methods and, optionally, one or more solutions suitable for conducting photometric measurements.

Abstract: According to the invention, a pipette or a dispenser (10) with a piston indicator (6) is characterized in that a display (2) shows the piston position (20).

Abstract: Hydrophobic coating compositions are provided as are processes to coat articles with the compositions. Extremely hydrophobic coatings are provided by the compositions. Durable, weatherable and scratch-resistant coatings are provided by compositions comprising a fluorinated component and an adhesion promoter compound. The adhesion promoter compound can include an alkoxy group, a furfuryl-containing ring structure, and a reactive group.

Abstract: The present invention relates to a smart pipette for bio-cell manipulation which can freely change orientation of a bio-cell subject to the manipulation by using mechanical friction and applying instantaneous impact when penetrating the subject bio-cell while receiving real-time feedback of force/torque information of the bio-cell. Further, the present invention relates to a bio-cell manipulation method and system using a smart pipette, through which a bio-cell may be manipulated upon the application of the force/torque information generated during the cell manipulation to the smart pipette control. According to the present invention, injection position can be recognized precisely and conveniently regardless of the proficiency of the manipulating person. Thus, the bio-cell manipulation may be automated. Further, the smart pipette quantifies force/torque information feed-backed through the sensor unit and compares it with data acquired in advance through experiments on the same bio-cell.

Abstract: A liquid pipetting apparatus for dispensing liquid of minute volume for use in a survey instruments of a hemanalysis machine, a genetic screening, and a pharmaceutical screening, etc., is disclosed. The liquid pipetting apparatus comprises a liquid holding member for holding the liquid, and capable of dispensing the liquid from one end, and a driving member for moving the liquid holding member forward and backward along the dispensing direction, the liquid holding member being moved by the driving means, thereby dispensing the liquid held on the liquid holding member.

Abstract: A pipettor head adapter allows the adaptation of pipettors having a set number of pipettor channels to successfully pipette microtiter trays having a different number of wells than the pipettor has pipettor channels. For example, in a pipettor having 384 channels for pipetting a 384 well microtiter tray, the pipettor head adapter of the present invention will allow a “stepping down” or adaptation, such that the pipettor with its 384 pipettor channels can successfully and reliably pipette microtiter trays having 96 wells. Such adaptation occurs without the need for special microtiter trays. Industry standard operations are then preserved, even though they were previously unavailable from such a pipettor.

Abstract: A pipette for the handling of a syringe. The pipette has jaw chucks which are adjustably arranged with respect to the plunger receptacle, being pivotably mounted on a plunger-gripping device. The syringe is insertable with opened jaw chucks with the plunger head only partially contacting the jaw chucks. The jaw chucks are laterally engageable on the plunger head upon insertion of the syringe. The engaging movement of the jaw chucks on the plunger head is regulated according to the invention so that the engaging movement has a substantially tangential component with respect to the surface of the plunger head. As a result, a desired and form-locking connection to the plunger head of the syringe results that requires a small amount of force.

Abstract: Invention performs an assay to determine presence or quantity of specific analyte in fluid sample. Representative device has two separate flow paths established sequentially in device with a single user activation step. First flow path delivers sample, and conjugate soluble binding reagents to solid phase. If analyte is present, an analyte:conjugate complex is formed and immobilized. Sample volume delivered by first path determined by absorbent capacity of solid phase, and not by amount of sample added to device. User need not measure sample volume. Sample/conjugate mixture is prevented from entering second flow path because capillary and surface energy of second flow path prevent it from being wetted by this mixture. Second flow path allows wash reagent to remove unbound conjugate and sample from solid phase to the absorbant, and optionally deliver detection reagents.

Abstract: An automatic immunoassay method and apparatus which not only permit automatic operations of supplying and discarding reaction tubes, washing for B/F separation, dispensation of reagents, and measurement, but also permit the reaction time to be varied arbitrarily and can cope with any of the assay techniques including one-step and two-step noncompetitive sandwich techniques and competitive techniques.

Abstract: There is provided a burette apparatus having a delivery tube connecting a fluid bag to a burette assembly, via a fluid entry spigot formed in an end cap assembly of the burette assembly, the end cap assembly having a bypass spigot connected to the delivery tube and usually closed by clip, to allow an override for adding liquid to the burette. The end cap assembly closes the upper end of the transparent, cylindrical burette body, into which extends a stainless steel tube extension of the fluid entry spigot, the lower end of the burette body being closed by a lower closure assembly having a check valve and a drip chamber. An outlet tube passes from the drip chamber to the patient via regulating clamp. A float assembly is located in the burette body including an extension rod provided with a resilient cup adapted to engage the open end of the stainless steel tube extension.

Abstract: Laboratory vessels are coated on an operational surface thereof with a hydrophobic coating polymer or reactive monomer to form a coating having an exposed surface populated with 30% by area or more terminal trifluoromethyl groups. Laboratory vessels coated with such coating solutions are provided having extremely low surface energies and high resistance to solvent attack. Methods of forming hydrophobic coatings on laboratory vessels are also provided and include methods of forming exposed coating surfaces having populations of from about 30% by area to 100% by area trifluoromethyl groups. The hydrophobic coatings may be prepared from solutions, suspensions or powdered materials containing a fluoroalkyl ethylenically unsaturated monomer substantially free of any crosslinking, having from about 3 to about 20 carbon atoms, and containing at least one terminal trifluoromethyl group, or containing a polymerization product of such a monomer.