Abstract: A composition of matter comprises a shelf stable, super critical, CO2 fluid extracted seed oil derived from a cracked biomass of perilla frutescens, the seed oil comprising from about 60 to about 95 percent w/w of PUFAs in a ratio of from about 4:1 to about 6:1 alpha-linolenic acid (ALA) to linoleic acid (LA) and a mixture of selected antioxidants.
Type:
Application
Filed:
September 13, 2011
Publication date:
February 2, 2012
Applicant:
U.S. Nutraceuticals, LLC d/b/a Valensa International
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: Blue-green algae, such as Aphanizomenon flos aquae (AFA) or Spirulina (Arthrospira) can be fractionated. Anti-inflammatory aqueous fractions of blue-green algae are described herein that include low molecular weight molecules. Methods for reducing inflammation in a subject are also described. These methods include administering to the subject compositions comprising a therapeutically effective amount of the anti-inflammatory aqueous fraction blue-green algae, or dried form thereof, thereby reducing inflammation.
Abstract: A biodegradable wound care product with biocompatible artificial skin treatment is described. It includes a biodegradable bandage support member and a biodegradable adhesive on at least a portion thereof. The support member is made of a biodegradable material, such as natural or artificial textiles, plastics or papers. The biodegradable actives carrier is attached to a portion of the biodegradable bandage support member and is a synthetic or natural biodegradable adhesive or a combination thereof. The active ingredient located on the biodegradable actives carrier includes a layer of biocompatible algae artificial skin including sterilized water and at least sixty percent by weight of reconstituted seaweed. Laminaria seaweed may be used for its desirable polyfucose sulfate content. The active ingredient is prepared by first drying the raw materials, converting the raw materials to a powder and then reconstituting the powder with sterilizes water and other possible actives and/or inerts.
Abstract: An enteral nutrient gel that is excellent at maintaining its solid matter (gel) form in the stomach, does not readily disintegrate or dissolve with a change in pH, is stable in its physical properties even during long-term storage, and can be passed through a feeding tube. The enteral nutrient gel contains agar, alginic acid and/or a salt thereof, soybean protein or a hydrolysate thereof, calcium, magnesium, dextrin, and, optionally, an oligosaccharide, a disaccharide and/or a monosaccharide. A solid composition containing 8 to 30 wt % protein, 2 to 25 wt % fats, and 40 to 70 wt % dextrin is used in preparing the enteral nutrient gel.
Abstract: A method of inhibiting a viral infection of a host comprising administering to the host an anti-viral griffithsin polypeptide comprising SEQ ID NO: 3 or a fragment thereof comprising at least eight contiguous amino acids, a nucleic acid encoding the anti-viral polypeptide, or an antibody to the anti-viral polypeptide. A method of inhibiting a virus in a sample comprising contacting the sample with an anti-viral griffithsin polypeptide or antibody thereto also is provided.
Type:
Grant
Filed:
December 1, 2006
Date of Patent:
January 3, 2012
Assignee:
The United States of America as represented by the Secretary, Department of Health and Human Services
Inventors:
Barry O'Keefe, Toshiyuki Mori, James B. McMahon
Abstract: A method of isolating nutraceuticals products from algae is provided. A method of isolating carotenoids and omega-3 rich oil from algae includes dewatering substantially intact algal cells to make an algal biomass and adding a first ethanol fraction to the algal biomass. The method also includes separating a first substantially solid biomass fraction from a first substantially liquid fraction comprising proteins and combining the first substantially solid biomass fraction with a second ethanol fraction. The method further includes separating a second substantially solid biomass fraction from a second substantially liquid fraction comprising polar lipids and combining the second substantially solid biomass fraction with a third ethanol solvent fraction.
Abstract: A formulation includes water, shea butter, an emulsifier and an essential oil comprising myrrh. In addition, the formulation can include cocoa butter, coconut oil, kelp powder, and a preservative comprising a mixture of phenoxyethanol, methylparaben, ethylparaben, propylparaben and butylparaben. The formulation can be used for cosmetic applications in which the formulation is applied as a cream to a user's skin.
Abstract: For the purpose of providing a method of safely and inexpensively producing a fermented plant extract containing an immunopotentiator at a high concentration, the method for fermentation and culture of the present invention ferments a plant component such as wheat flour using Pantoea agglomerans which is a gram negative bacterium which lives in a symbiotic relationship with a plant such as wheat and apple. It becomes possible to remarkably augment an immunopotentiation action which the plant has. In addition, these are not contaminated with impurities derived from animal components, and thus these are highly safe.
Abstract: The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a lipid globules coated with phospholipids. The composition is used for increasing bone mineral content, bone mineral density, preventing osteoporosis, and/or preventing ostopenia.
Type:
Application
Filed:
December 11, 2009
Publication date:
December 8, 2011
Inventors:
Eline Marleen Van Der Beek, Gelske Speelmans, Annemarie Oosting, Antonie Van Baalen, Marieke Abrahamse-Berkenveld, Günther Boehm
Abstract: The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a large lipid globule size, having a volume weighted mode diameter above 1.0 ?m and/or with a diameter of 2 to 12 ?m in a amount of at least 45 volume % based on total lipid. The composition can be used to increase bone mineral content and/or bone mass density, to prevent osteoporosis and/or osteopenia and for the further prevention of obesity.
Type:
Application
Filed:
December 11, 2009
Publication date:
December 8, 2011
Inventors:
Eline Marleen Van Der Beek, Gelske Speelmans, Antonie Van Baalen, Annemarie Oosting, Günther Boehm
Abstract: A Salvia hispanica L. derived seed oil extract composition of matter containing from 60-88% PUFAS in a ratio of from 3.1:1-3.3:1 of ALA to LA, 4-10% of C-18 mono-unsaturated fatty acid, 1-5% of C-18 saturated fatty acid and 4-8% of C-16 saturated fatty acid in a mixed triglyceride form stable at room temperature of 12-24 months containing a mixture of selected antioxidants.
Type:
Application
Filed:
August 10, 2011
Publication date:
December 1, 2011
Applicant:
U.S. NUTRACEUTICALS, LLC, D/B/A VALENSA INTERNATIONAL
Inventors:
John A. MINATELLI, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: Nutritional food oil compositions containing all of the essential fatty acids and the highly recommended omega-3 fatty acid DHA in correct proportions making it convenient and easy for consumers to supplement their diets with these fatty acids in the proper amounts, thereby deriving the health benefits of these fatty acids. A nutritional food oil composition is provided comprising alpha-linolenic acid (ALA) and linoleic acid (LA), wherein the ratio of the amount of ALA to LA in the composition by weight is in the range of 1.5:1 to 6:1, and together the ALA and LA comprise at least 65% by weight of the composition, and docahexaenoic acid (DHA) from an algal source in an amount greater than 0.5% by weight of the composition.
Abstract: The present invention concerns a topical formulation for the treatment of cellulite, comprising alfalfa herb and derivatives thereof and can further comprise melatonine. The invention refers also to a method of application of said formulation and to a pharmaceutical kit for the treatment of cellulite comprising said formulation, together with vegetal or mineral mud.
Abstract: A composition comprises extract of fucoxanthin, wherein said composition further comprises tocotrienols and/or fucoidan. Said composition can be used to treat obesity. Said composition shows outstanding effect of weight loss. There is outstanding synergy effect among those constituents of the composition.
Type:
Application
Filed:
January 19, 2009
Publication date:
November 10, 2011
Applicant:
Beijing Gingko Group Biological Technology Co., Ltd.
Abstract: Cooling of the human body is accomplished by topical application of a treatment composition including an extract of a green marine algae. A preferred green marine algae is enteromorpha compressa.
Abstract: Disclosed herein is a lipid preparation, said preparation comprising a phosphatidylserine moiety, and poly-unsaturated fatty acid (PUFA) acyl groups, particularly long-chain poly-unsaturated fatty acid (LC-PUFA) acyl groups such as omega-3 and/or omega-6 acyl groups, wherein said PUFA is covalently bound to said glycerophospholipid. Said lipid preparations are particularly useful in the treatment of mental and cognitive disorders, e.g. ADHD (attention deficit hyperactivity disorder) and Alzheimer's disease. The disclosed preparations present improved bioactivity, and are useful in the treatment of various cognitive and mental conditions and disorders, as well as for maintenance of normal functions of brain-related systems and processes.
Type:
Grant
Filed:
April 28, 2006
Date of Patent:
November 8, 2011
Assignee:
Enzymotec Ltd.
Inventors:
Gai Ben Dror, Dorit Plat, Orly Farkash, Rassan Zuabi, Zohar Bar-On, Avidor Shulman, Dori Pelled
Abstract: The invention relates to a method for the cosmetic prevention and/or treatment of stretch marks on the skin, characterised in that the method comprises administering a composition containing arabinogalactan as an active principle to a person that may develop or has stretch marks. Said cosmetic composition can be administered in a topical or oral manner.
Type:
Application
Filed:
November 9, 2009
Publication date:
November 3, 2011
Inventors:
Philippe Msika, Caroline Baudouin, Dalale Naaimi, Franck Menu
Abstract: The invention provides methods of treatment that induce satiety in a subject for a period of at least around twenty-four hours by once-daily administration to the subject of a controlled release dosage form, wherein the dosage form is administered while the subject is in the fasted state and at a time of around six to around nine hours prior to the subject's next intended meal, and wherein the dosage form comprises a controlled release composition, which comprises an enterically-coated, ileum hormone-stimulating amount of a nutritional substance and releases the majority of the nutritional substance in vivo upon reaching the subject's ileum. The invention also provides a diagnostic tool for probing the health and disease state of the ileal hormones, excess or deficiencies. The invention provides a safe vehicle for targeted deliveries of chemical, pharmaceuticals, natural substances and nutrition to the ileum.
Abstract: A composition and method which improves blood lipid profiles and optionally reduces low density lipoprotein (LDL) per-oxidation in humans by administering a therapeutic amount of a composition comprising krill oil in combination with astaxanthin or a mixture of fish oil derived, choline based, phospholipid bound omega-3 fatty acid mixture including phospholipid bound polyunsaturated EPA and DHA. In one embodiment, the krill oil is derived from Euphasia spp., comprising Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) fatty acids in the form of triacylglycerides and phospholipids. The krill oil includes at least 10% EPA and 5% DHA, of which greater than 50% are in the form of phospholipids and the 1-4000 mg of krill oil per daily dose is delivered.
Type:
Application
Filed:
April 25, 2011
Publication date:
November 3, 2011
Applicant:
U.S. Nutraceuticals, LLC d/b/a Valensa International
Inventors:
John A. MINATELLI, W. Stephen Hill, Rudi E. Moerck
Abstract: An invention relates to an extract of Chlorella sorokiniana, which contains myristic acid, palmitic acid, palmitoleic acid, oleic acid, linoleic acid, linolenic acid, and stearic acid. Also related is use of this extract to treat diabetes, obesity, and dyslipidaemia.
Type:
Grant
Filed:
October 16, 2008
Date of Patent:
November 1, 2011
Assignee:
International Chlorella Co., Ltd.
Inventors:
Hsing-Pang Hsieh, Tsu-An Hsu, Yu-Sheng Chao, Yu-Cheng Chou, Shun Te Wang
Abstract: A cosmetic composition is disclosed for applying to skin. The composition includes a liquid and dispersed in the liquid: any amount or form of fucoidan, any amount or form of beta glucan; and any amount of a marine extract. When the cosmetic composition is applied to the skin, the appearance of the skin is improved.
Abstract: Methods and compositions for increasing intestinal transport of nutrients or growth performance in the offspring of an animal are described. More specifically, a feed composition comprising an omega-3 fatty acid-containing composition for increasing intestinal transport of nutrients or growth performance in the offspring of the animal, and methods therefor, are described.
Abstract: The present invention relates to a method of preventing or treating allergic diseases such as allergic rhinitis, atopic dermatitis, anaphylaxis, and asthma, which comprises administering an extract of Laurencia undulata in a therapeutically effective amount to a patient in need thereof.
Type:
Application
Filed:
June 28, 2011
Publication date:
October 20, 2011
Inventors:
Won-Kyo Jung, Il-Whan Choi, Se-Kwon Kim, Sung Su Yea, Yung Hyun Choi, Inhak Choi
Abstract: The invention provides cosmetic compositions comprising microalgal biomass, whole microalgal cells, and/or microalgal oil in combination with one or more other cosmetic ingredients, and methods of making such compositions. In preferred embodiments, the microalgal components of the cosmetic compositions are derived from microalgal cultures grown heterotrophically and which comprise at least 10% oil by dry weight.
Abstract: A natural composition comprising myrtle berries; seaweed; and at least two of tea tree oil, lemongrass oil, evening primrose oil, ginger, jojoba oil, neem oil, and chamomile, and uses thereof for treatment of skin conditions.
Abstract: Consumption of blue-green algae, or extracts thereof, enhances trafficking or homing of stem cells in animals by inducing a transient increase in the population of stem cells present in the animal's circulatory system. The animal may be healthy or suffering some disease or physiological condition.
Abstract: Disclosed is a self-adhesive matrix system comprising a styrene-ethylene/butylene-styrene (SEBS) copolymer in an oil/ethyl acetate mixture, a hydrogenated resin and a pharmaceutical or cosmetic active ingredient.
Type:
Application
Filed:
December 10, 2009
Publication date:
October 6, 2011
Inventors:
Stefania Pagani, Maurizio Di Grigoli, Sergio Comuzio
Abstract: The present invention relates to a composition for treating diabetes and a preparation method thereof as well as use thereof. The present invention provides a composition for treating the diabetes, comprising the following active components based on the parts by weight: 10-100 parts of Pumpkin powder; 6-200 parts of spirulina; and 2-90 parts of Lychee Seed. The invention further provides the preparation method of the composition and the use of the medicament for treating the diabetes. By taking the composition, the blood sugar concentration of the diabetics can be effectively controlled, the complicating diseases of the diabetics can be avoided, and the health of the diabetics can be protected.
Abstract: The object of the invention is the use in a cosmetic composition of an effective amount of at least one cutaneous cell autophagy activator as a cosmetic active ingredient. The invention also relates to cosmetic compositions that include at least one cutaneous cell autophagy activator as a cosmetic active ingredient 5 and a cosmetic process for detoxifying skin and/or for preventing or combating cutaneous aging.
Abstract: The invention provides methods of cultivating microalgae photoautotrophically outdoors to prepare concentrated microalgae products containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) docosahexaenoic acid, two long-chain polyunsaturated fatty acids found in fish oil that are very important for human and animal health. It also provides concentrated microalgae products containing EPA and DHA and purified lipid products containing EPA and DHA purified from microalgae.
Type:
Grant
Filed:
January 10, 2007
Date of Patent:
October 4, 2011
Assignee:
Parry Nutraceuticals, Division of E.I.D. Parry (India) Ltd.
Inventors:
Swati Sebastian Thomas, Swaminathan Kumaravel
Abstract: The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, LDL, triglycerides, blood glucose, leptin and C-reactive protein levels and increase in HDL and serotonin levels in an mammal. The LeptiCore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications. The higher dosage resulted in significantly greater reductions in body weight and triglyceride, blood glucose, and C-reactive protein levels, as well as increased serotonin levels.
Abstract: Topical skin care compositions containing a combination of ascorbic acid or a derivative thereof, brown algae extract, and a blend of botanical extracts comprising cucumber extract, watercress extract, birch leaf extract, red clover extract, and St. John's wort extract, and, optionally, ginseng extract, as well as methods of using the same, are disclosed.
Type:
Application
Filed:
March 17, 2011
Publication date:
September 22, 2011
Applicant:
ARBONNE INTERNATIONAL LLC
Inventors:
Peter Matravers, Deborah Hicks, Sheree Wiener, Michele Arth
Abstract: A comestible composition with anti-cancer property comprises alcohol soluble extracts from plant parts of Piper species, palm species, tropical seaweeds, and/or Solanum species.
Abstract: The invention relates to a novel cosmetic active ingredient composed of a microalgae extract and arginine ferulate, its uses for activating proteasome and the production of thioredoxin, a cosmetic composition containing it and the use of such a cosmetic composition for combating skin ageing.
Abstract: The present invention relates to the use of a composition comprising at least one cell membrane fraction or parts thereof, for the reduction of lipolytic activity and/or to retard fat digestion, suppress appetite, body weight and/or lower blood lipids. The invention also relates to the use of said hydrophobic peptide in a pharmaceutical as well as a food composition and methods of treating a mammal with said composition.
Type:
Application
Filed:
February 24, 2011
Publication date:
August 25, 2011
Inventors:
Per-Åke Albertsson, Charlotte Albertsson-Erlanson
Abstract: The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a large lipid globule size. The composition can be used to prevent obesity and/or improve body composition later in life. Said lipid component comprises 10-50 wt % vegetable lipids, and the lipid globules have a volume-weighted diameter above 1.0 m and/or a diameter of 2-12 m in an amount of at least 45 vol %.
Type:
Application
Filed:
September 2, 2009
Publication date:
August 25, 2011
Inventors:
Antonie Van Baalen, Eline Marieen Van Der Beek, Christopher Beermann, Günther Boehm
Abstract: A method of isolating nutraceuticals products from algae is provided. A method of isolating carotenoids and omega-3 rich oil from algae includes dewatering substantially intact algal cells to make an algal biomass and adding a first ethanol fraction to the algal biomass. The method also includes separating a first substantially solid biomass fraction from a first substantially liquid fraction comprising proteins and combining the first substantially solid biomass fraction with a second ethanol fraction. The method further includes separating a second substantially solid biomass fraction from a second substantially liquid fraction comprising polar lipids and combining the second substantially solid biomass fraction with a third ethanol solvent fraction.
Abstract: A self-adhesive polymer matrix which comprises a polymer that forms a gel in water, water, a sea algae extract, and a monohydric or polyhydric alcohol.
Abstract: The present invention relates to a method of preventing or treating allergic diseases such as allergic rhinitis, atopic dermatitis, anaphylaxis, and asthma, which comprises administering an extract of Laurencia undulata in a therapeutically effective amount to a patient in need thereof.
Type:
Grant
Filed:
November 25, 2008
Date of Patent:
August 9, 2011
Assignee:
Pukyong National University Industry-Academic Cooperation
Inventors:
Won-Kyo Jung, Il-Whan Choi, Se-Kwon Kim, Sung Su Yea, Yung Hyun Choi, Inhak Choi
Abstract: A composition to be orally administered and/or topically applied for enhancing wound healing, tissue repair and cardiovascular health protection comprising an extract of vegetative parts of Ipomoea, Arecaceae plant family and/or seaweeds through extraction using alcoholic solvent with or without combination with a co-solvent, which may be aqueous or organic as an active ingredient.
Type:
Application
Filed:
September 29, 2009
Publication date:
August 4, 2011
Inventors:
Suhaila Mohamed, Rosalina Roslan Tan, Samaneh Ghasemi, Mehdi Javadi, Maslia Manja, Kharidah Muhammad
Abstract: The subject invention pertains to novel biologically active extracts from marine algae and to biologically active fractions and components of these extracts. These extracts have been shown to possess antiviral properties. Pharmaceutical compositions comprising these extracts, or comprising biologically active fractions or components of these extracts, could be used in the treatment of viral diseases including influenza.
Type:
Application
Filed:
January 14, 2011
Publication date:
August 4, 2011
Inventors:
Alberto van Olphen, Bill J. Baker, Dennis E. Kyle, Cynthia Bucher, Alan Maschek, James B. McClintock, JR., Charles D. Amsler
Abstract: A method for enhancing antioxidant components of Gracilaria tenuistipitata extract is proposed. The method involves providing an extraction environment of 40° C., and performing cyclic grinding to a Gracilaria tenuistipitata solution with an ultrasonic disrupter outputting a vibrating frequency between 20 KHz and 45 KHz for 60 to 120 minutes, so as to stabilize chemical properties of the Gracilaria tenuistipitata solution and obtain a Gracilaria tenuistipitata extract having more activated protein and phycoerythrin as compared with an extract obtained through the prior art, thereby improving the Gracilaria tenuistipitata extract in antioxidative ability.
Abstract: The present invention relates to a process on a large industrial scale for the production of thylakoids, from photosynthetic organisms, such as from green plant leaf material, to be used as ingredients in food, or additions to food, or dietary supplements, or pharmaceuticals for the purpose of preventing overweight, promoting satiety, reducing food intake, reducing bodyweight, reducing blood insulin concentration and reducing blood fats and percentage body fat in humans and animals.
Type:
Application
Filed:
June 24, 2009
Publication date:
July 28, 2011
Inventors:
Charlotte Erlanson-Albertsson, Per-Åke Albertsson, Gösta Lilius, Malin Olbe
Abstract: The present invention relates to a method for forming a temporary obstruction of the intestine of a mammal, using a solidifiable composition, said composition being flow-able and solidifiable to form a solid plug at a desired site within the intestine, the structure of said plug being changeable in order to allow for the subsequent, at least partial removal of the obstruction.
Abstract: A nutritional supplement includes the primary ingredients: N-acetyl D-glucosamine, cracked cell wall Green Chlorella, Licorice Root Extract, and Potassium Citrate, as well as secondary ingredients: Zinc L-Carnosine, Gamma-Oryzanol and Capsaicin, that improves the bodies uptake, utilization and over-all bioavailability of exogenous target protein fractions (TPF) including but not limited to: glycoproteins,(such as glucosamine) protein isolates as amino acids, glycosaminoglycans (GAG) (including proteoglycans, and mucopolysaccharides), and polysaccharides such as hyaluronic acid (hyaluronan). The biochemical interactions of the composition improves zeta potential for TPF incorporation in the body through direct and indirect interaction with primary cellular and digestive sites of multiple species.
Abstract: The invention provides anti-aging agents, angiogenesis inhibitors and vascular endothelial growth factor (VEGF) expression inhibitors containing one or more galenicals selected from the group consisting of mukurossi peel extract, hazelnut extract, linden extract, coix extract, chlorella extract and tormentilla extract.
Abstract: A wound care dressing comprising one or more nonwoven blankets, where each nonwoven blanket comprises a plurality of fibers, where each of the plurality of fibers are formed from one or more saccharides in optional combination with one or more medicaments.
Abstract: A lipid preparation including a glycerophospholipid or salt, conjugate and derivatives thereof, particularly phosphatidylserine (PS), phosphatidyicholine (PC), phosphatidylethanolamine (PE), phosphatidyl-inositol (PI), phosphatidylglycerol (PG) and phosphatidic acid (PA), and poly-unsaturated fatty acid (PUFA) acyl groups, particularly long-chain poly-unsaturated fatty acid (LC-PUFA) acyl groups such as omega-3 and/or omega-6 acyl groups, wherein said PUFA is covalently bound to said glycerophospholipid. The preparation possesses an improved bioactivity, and is useful in the treatment of various cognitive and mental conditions and disorders and for maintenance of normal functions of brain-related systems and processes.
Type:
Grant
Filed:
October 15, 2007
Date of Patent:
June 28, 2011
Assignee:
Enzymotec Ltd.
Inventors:
Gai Ben Dror, Dorit Plat, Orly Farkash, Rassan Zuabi, Zohar Bar-On, Avidor Shulman, Dori Pelled
Abstract: The invention relates to adhesives for medical applications and methods of their preparation and use.
Type:
Application
Filed:
March 1, 2011
Publication date:
June 23, 2011
Inventors:
Andreas Werner Speitling, Philip Procter, Joachim Schomburg, Christian Schultz, Wolf-Dieter Jülich, Ulrike Lindequist, Frieder Schauer, Annett Mikolasch, Katrin Manda
Abstract: A process for obtaining algae extracts, includes at least the following stages: a) pretreatment of an algal sample, b) rapid heating, c) application of pressure that is greater than or equal to 1 bar, d) instantaneous expansion to a pressure that is less than or equal to 1 bar, and e) recovery of the products that are obtained in d) in liquid, solid and/or gaseous form. The use of algae extract products obtained by the implementation of this process is also described.