Inorganic Particle Patents (Class 424/421)
  • Patent number: 9877434
    Abstract: The present application relates to methods and compositions and compositions for watering plant roots, and more particularly, to water soluble granular compositions for application to grass and other root bearing plants, the granules including a wood, mineral and binder granule impregnated with a root watering composition having a humectant as its principle constituent, and methods of application and use of the granular compositions.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: January 30, 2018
    Assignee: Ecologel Solutions, LLC
    Inventor: Richard K. Irwin
  • Patent number: 9686997
    Abstract: The invention is generally directed to antimicrobial composition comprising a matrix material and both of silver and zinc distributed there through, wherein the matrix material comprises at least one of Si02, Ti02, Zr02, AI203, or Zeolite, and the uses of such compositions as antibacterial and acaricidal. The invention is also generally directed to antimicrobial composition comprising a matrix material arid both of silver and a metal selected from the group of noble or transition metals distributed there through, wherein the matrix material comprises at least one of Si02, Ti02, Zr02, AI203, or Zeolite, and the uses of such compositions as antibacterial and acaricidal.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: June 27, 2017
    Assignee: NANOX TECHNOLOGY LLC
    Inventors: Luiz Gustavo Pagotto Simões, Andre Luiz De Araújo, Daniel Tamassia Minozzi
  • Patent number: 9578876
    Abstract: The present disclosure relates to water dispersible granular pesticide compositions, and methods of making and using the compositions. The pesticide compositions include an inner layer including a first pesticide coated on to a substrate, and an outer layer comprising a second pesticide coated on the inner layer. The outer layer increases the water dispersibility of the granular composition, and protects the first pesticide against hydrolysis and photolysis.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: February 28, 2017
    Assignee: Ecolab USA Inc.
    Inventors: Victor F. Man, Yvonne M. Killeen, Susan M. Viall
  • Patent number: 9549878
    Abstract: A set of a first and a second preparation are intended to be mixed before or during an endodontic treatment to form an endodontic irrigation solution. The first preparation includes an oxidizing agent. The second preparation includes antibacterial nanoparticles treated to slow their oxidation by the oxidizing agent. The antibacterial nanoparticles are, for example, encapsulated in shells in a hybrid core-shell structure. In one variation, the antibacterial nanoparticles are made from an alloy of at least two elements, one of the elements being more resistant to oxidation than the other.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: January 24, 2017
    Assignee: MAILLEFER INSTRUMENTS HOLDING SARL
    Inventors: Benjamin Le Ouay, Francesco Stellacci, Janine Conde, Selma Mefti
  • Patent number: 9433581
    Abstract: The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using Pluronic F68 as surfactant, to create spherical nanostructures measuring about 200-250 nm in diameter which are stable in phosphate buffer and blood serum, and only slowly degrade in the presence of esterases. Kinetics experiments in phosphate buffer indicate that 78% of the coumarin-6 was encapsulated within the polymer matrix of the nanoparticle, and the residual 22% of coumarin-6 was surface-bound and quickly released. The nanoparticles are non-toxic in vitro towards human epithelial cells (IC50>1000 ?g/mL) and primary bovine primary aortic endothelial cells (IC50>500 ?g/mL), and exert non-observable bactericidal activity against a selection of representative test microbes (MIC>250 ?g/mL).
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: September 6, 2016
    Assignee: University of South Florida
    Inventors: Edward Turos, Raphael Labruere, Ryan Scott Cormier, Renaud Sicard
  • Patent number: 9173406
    Abstract: The invention relates to an antimicrobial and non-cytotoxic coating material and to uses of said coating material.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: November 3, 2015
    Assignee: Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V.
    Inventors: Michael Wagener, Dirk Salz, Klaus-Dieter Vissing
  • Patent number: 9167752
    Abstract: The present disclosure provides systems and methods for inoculating a plurality of plants. In various embodiments, an exemplary method includes spraying a plurality of plants with an inoculum utilizing an automated inoculum spraying subsystem of a mobile inoculation system. The method additionally includes spraying the plurality of plants with a grit medium utilizing an automated grit blasting subsystem of the mobile inoculation system. Spraying the plants with the grit medium inflicts a plurality of wounds to the tissue of the plants on a plurality of surfaces of the plants. The wounds inflicted by the grit medium allow the inoculum to be absorbed into the plants to inoculate the plants.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: October 27, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Jeffrey W. Hartsook, Michael R. Bohnert, David J. Baitinger, Ana Paula da Silva Dias, Travis J. Frey
  • Publication number: 20150140056
    Abstract: The present disclosure relates to water dispersible granular pesticide compositions, and methods of making and using the compositions. The pesticide compositions include an inner layer including a first pesticide coated on to a substrate, and an outer layer comprising a second pesticide coated on the inner layer. The outer layer increases the water dispersibility of the granular composition, and protects the first pesticide against hydrolysis and photolysis.
    Type: Application
    Filed: January 23, 2015
    Publication date: May 21, 2015
    Inventors: Victor F. Man, Yvonne M. Killeen, Susan M. Viall
  • Patent number: 9011893
    Abstract: The embodiments relate to cosmetic compositions providing high coloring pigment particles capable of achieving high color coverage with less pigment. The compositions of embodiments include aluminum hydroxide particles coated with at least one pigment, and having an average coated ratio of from about 20% to about 100% pigment by weight of aluminum hydroxide, and a cosmetically acceptable carrier. The compositions may be useful as a foundation and/or as a composition to correct skin discoloration.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: April 21, 2015
    Assignee: U.S. Cosmetics Corporation
    Inventors: Katsumi Shimizu, Shoji Takekawa
  • Patent number: 8999363
    Abstract: The present invention comprises methods and compositions for treating solid surfaces having antimicrobial and biocidal properties. Such surfaces are capable of controlling or killing a broad spectrum of biological agents, including viruses, bacteria and other microbial agents in solids, liquids or gases that subsequently contact the treated surface.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: April 7, 2015
    Assignee: Sishield Technologies, Inc.
    Inventor: Jacques Elfersy
  • Patent number: 8992960
    Abstract: Briefly described, embodiments of this disclosure, among others, include compositions, gels, methods for synthesizing multifunctional silica based nanoparticle gel, method of treating, preventing, or both treating and preventing, a disease in a plant species, method for simultaneously treating citrus plants for citrus canker and preventing the invasion of an Asian Citrus Psyllid (ACP) vector that carries the pathogen and spreads the citrus greening disease in citrus plants, and the like.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: March 31, 2015
    Inventor: Swadeshmukul Santra
  • Publication number: 20150071980
    Abstract: Methods directed to the synthesis of metal nanoparticles are described. A formation process can be carried out at ambient temperature and pressure and includes the deposition of metal ions on a titanate carrier according to a chemical deposition process followed by exposure of the metal ions to a reducing agent. Upon the exposure, nanoparticles of the reduced metal are formed that are adhered to the titanate carrier.
    Type: Application
    Filed: September 6, 2013
    Publication date: March 12, 2015
    Applicant: Savannah River Nuclear Solutions, LLC
    Inventors: David T. Hobbs, Kathryn M.L. Taylor-Pashow, Mark C. Elvington
  • Patent number: 8968754
    Abstract: The present invention provides a titanium dioxide dispersion having a good dispersibility and also provides a cosmetic containing the same. The titanium dioxide dispersion comprises (a) a hydrophobized, treated titanium dioxide powder; (b) one or more oils selected from isohexadecane, isododecane, 2-ethylhexyl 2-ethylhexanoate, isononyl isononate, 2-ethylhexyl isononanoate, isononyl 2-ethylhexanoate, and polypropylene glycol dipivalate; and (c) a siloxane compound represented by the following formula (1), preferably polyoxyalkylene/alkyl comodified organopolysiloxane.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: March 3, 2015
    Assignee: Shiseido Company, Ltd.
    Inventor: Susumu Yoshida
  • Publication number: 20150056260
    Abstract: A metal nanoparticles-doped porous carbon bead having an average size of about 0.4 millimeter (mm) to about 0.6 mm is provided. The metal nanoparticles-doped porous carbon bead is doped with silver, copper, or combinations thereof.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 26, 2015
    Inventors: Nishith VERMA, Ashutosh SHARMA, Prateek KHARE
  • Publication number: 20150056259
    Abstract: Nanoengineered particulate coatings (NPCs) comprise a multiplicity of particulate hosts that are infused with a nanophase comprising a surfactant and at least one guest. The particulate hosts can be clay particles, the surfactant can be a cationic surfactant, and the guest can be an insect repellant. For example, montmorillonite particles infused with hexadecyl trimethyl ammonium bromide and garlic oil form NPCs that may be used to form an emulsion or suspension for spraying on citrus trees to repel Asian Citrus Psyllid.
    Type: Application
    Filed: February 14, 2013
    Publication date: February 26, 2015
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Parvesh Sharma, Aarthi Narayanan, Hassan E. El-Shall, Brij M. Moudgil
  • Patent number: 8927002
    Abstract: The invention relates to a stent with in particular a coated basic body made of an implant material the use of lithium salts as a coating material or a component of an implant material for stents and the use of lithium salts in a method for restenosis prevention. The inventive stent having a basic body made of an implant material is characterized in that (i) the basic body has a coating which comprises or consists of a lithium salt, and/or (ii) the implant material is biocorrodible and the basic body contains a lithium salt.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: January 6, 2015
    Assignee: Biotronik VI Patent AG
    Inventor: Eric Wittchow
  • Publication number: 20140322286
    Abstract: It is an object of the present disclosure to provide zinc oxide powders having an average particle diameter of 1.1 ?m or more and having an antibacterial property, an antibacterial agent comprising the same, and an antibacterial composition containing the same. Surface treated zinc oxide powders which have an average particle diameter of 1.1 ?m or more, and which are surface treated by using at least one compound selected from the group consisting of silicon oxide, silicone oil, organic silicon compounds, and organic titanium compounds.
    Type: Application
    Filed: November 14, 2012
    Publication date: October 30, 2014
    Applicant: Sakai Chemical Industry Co., Ltd.
    Inventors: Mitsuo Hashimoto, Koichiro Magara, Kunitada Nishida
  • Publication number: 20140308330
    Abstract: Quaternary ammonium materials may be immobilized onto a metal oxide nanoparticle to provide a fixed-quat nanoparticle material. A particular example uses a silicon alkoxide as a silicon source material to provide a fixed-quat SiNP/NG material composition through either acidic or basic hydrolysis of the silicon alkoxide material. Particular materials may be characterized spectroscopically to ensure that the desirable materials are properly bound. Specific applications of fixed-quat SiNP/NC material compositions in accordance with the embodiments include, but are not limited to agricultural biocide applications and tobacco smoke selective filtration applications.
    Type: Application
    Filed: April 9, 2014
    Publication date: October 16, 2014
    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Swadeshmukul Santra, Joshua Bazata, Mikaeel Young
  • Patent number: 8840916
    Abstract: A polymer and a method for its preparation are provided. The polymer comprises poly(lactide), poly(lactide/glycolide) or poly(lactic acid/glycolic acid) segments bonded by ester linkages to both ends of an alkanediol core unit. The polymer is for use in a controlled release formulation for a medicament, preferably leuprolide acetate. The controlled release formulation is administered to a patient as a subcutaneous depot of a flowable composition comprising the polymer, a biocompatible solvent, and the medicament. Controlled release formulations comprising the polymer release leuprolide for treatment of prostate cancer patients over periods of 3-6 months.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: September 23, 2014
    Assignee: Tolmar Therapeutics, Inc.
    Inventor: Richard L. Dunn
  • Patent number: 8815272
    Abstract: An environment-friendly porous bead-satellite nanoparticles composite which has excellent recovery and repeated usage performance and can be used as a catalyst, an antiviral agent, or an antimicrobial, and a fabrication method thereof are provided. The porous bead-satellite nanoparticles composite includes a porous bead, a molecule having a first end coupled to the surface of the porous bead and including a functional group at a second end, and satellite nanoparticles coupled to the functional group, wherein the porous bead may have a core-shell structure including a cluster core of nanoparticles and a porous bead shell covering the cluster core.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: August 26, 2014
    Assignee: Korea Institute of Science and Technology
    Inventors: Kyoungja Woo, Hye Hun Park, Wooyoung Park
  • Patent number: 8754146
    Abstract: Antimicrobial granules comprise carrier particles agglomerated by a binding agent containing a quaternary ammonium organosilane.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: June 17, 2014
    Assignee: Dow Corning Corporation
    Inventors: Nicoias Ziolkowski, Jean-Paul Lecomte, Nathalie Wauthier, Veronique Verhelst, Flore Vandemeulebroucke
  • Publication number: 20140135421
    Abstract: The disclosure provides a coating composition comprising a treated inorganic particle having reduced photoactivity and improved anti-microbial properties, wherein the treated inorganic particle comprises: an inorganic core particle; a first treatment of a silicon compound, wherein the silicon compound is added in a single step; and a second treatment comprising co-precipitated zinc oxide and alumina.
    Type: Application
    Filed: June 20, 2012
    Publication date: May 15, 2014
    Applicant: E I DU PONT DE NEMOURS AND COMPANY
    Inventor: Charles David Musick
  • Patent number: 8715704
    Abstract: The invention relates to a lure for attracting, and in some circumstances, killing dust mites, especially house dust mites. The lure comprises neryl formate and/or limonene and is usually arranged in powder form to allow it to be shaken over an area containing the mites. What about liquid that dries.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: May 6, 2014
    Assignees: London School of Hygiene & Tropical Medicine, Rothamsted Research Limited
    Inventors: Amanda Skelton, Mary Cameron, Michael Alexander Birkett, John Anthony Pickett
  • Publication number: 20140105953
    Abstract: The application discloses the formation of antimicrobial glass-ceramic articles having an amorphous phase and a crystalline phase and an antimicrobial agent selected from the group consisting of silver, copper and a mixture of silver and copper. The antimicrobial glass-ceramic can have a Log Reduction of >2.
    Type: Application
    Filed: October 11, 2012
    Publication date: April 17, 2014
    Inventors: George Halsey Beall, Nicholas Francis Borrelli, Robert Michel Morena, Charlene Marie Smith, Ying Wei
  • Publication number: 20140093551
    Abstract: Provided is a photocatalytic composition comprising zinc (Zn) doped titanium dioxide (TiO2) nanoparticles, wherein the ratio of titanium dioxide nanoparticles to zinc is from about 5 to about 150. The photocatalytic composition absorbs electromagnetic radiation in a wavelength range from about 200 nm to about 500 nm, and the absorbance of light of wavelengths longer than about 450 nm is less than 50% the absorbance of light of wavelengths shorter than about 350 nm. Further provided is a method for treating or preventing microbial diseases and infestations in a plant and a method for increasing crop yield of a plant by applying the photocatalytic compositions taught herein to the surface of a plant. Also provided is a method for treating microbial diseases on a surface by applying the photocatalytic compositions taught herein to a surface illuminated by artificial light.
    Type: Application
    Filed: November 1, 2013
    Publication date: April 3, 2014
    Inventors: Stewart Benson Averett, Devron R. Averett
  • Publication number: 20140086970
    Abstract: An antimicrobial system including inert carrier particles coated with a silver salt in combination with a primary disinfectant is disclosed. Some aspects relate to a disposable wipe for use in cleaning and disinfecting, the disposable wipe including a antimicrobial system. Other aspects relate to a sprayable disinfectant including a liquid carrier. Inert carrier particles, coated with a silver salt, are dispersed in the liquid carrier with a primary disinfectant. Optional additives including surfactants, dispersants, and stabilizers, may also be added.
    Type: Application
    Filed: March 23, 2012
    Publication date: March 27, 2014
    Applicant: SILVER ANTI-BAC, LLC
    Inventor: Thomas D. White
  • Patent number: 8679515
    Abstract: Contaminants are filtered from a fluid flow stream and the filter is regenerated by a process including steps of: providing a filter material comprising both carbon and potassium iodide; passing a contaminated fluid stream in contact with the filter material; adsorbing contaminants from the fluid stream onto surfaces in the filter material; passing an electric current through the filter material with adsorbed contaminant thereon; disassociating contaminant from the surfaces of the filter material; and removing disassociated contaminant from the filter material by carrying away the disassociated contaminant in a fluid flow mass. Separately, a stable, active iodine solution is also provided for numerous deodorizing and disinfecting applications.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: March 25, 2014
    Assignee: Biolargo Life Technologies, Inc.
    Inventors: Kenneth R. Code, Joseph Provenzano
  • Patent number: 8647652
    Abstract: Methods for preparing silver colloids and silica-coated silver colloids are disclosed. The silver colloids may be prepared by heating a silver-containing solution, combining the heated silver-containing solution with an acid solution, and cooling the combined solutions to form a silver colloid containing silver particles. The silver particles in the silver colloid can further be coated with silica. A method for preparing antimicrobial coatings is also disclosed.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: February 11, 2014
    Assignee: Guardian Industries Corp.
    Inventor: Pramod K Sharma
  • Patent number: 8647679
    Abstract: Disclosed herein are core-shell type zinc oxide microparticles, a dispersion containing such microparticles, and a production process and uses of the microparticles and the dispersion. As disclosed herein, the core-shell type zinc oxide microparticles have an average particle diameter of from 50 to 1,000 nm. The core is a secondary particle of spherical shape to the surface of which a polymer is attached as a shell. Methods for making the microparticles include the steps of: mixing together a zinc salt and a polymer in an organic solvent so as to obtain a mixture; and heating/refluxing the mixture at a predetermined temperature so as to cause core-shell type zinc oxide microparticles to precipitate, wherein the zinc salt is zinc acetate; and uses such as cosmetics, resins and fibers which contain the core-shell type zinc oxide microparticles and have an ultraviolet light blocking action.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: February 11, 2014
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Noriya Izu, Ichiro Matsubara, Toshio Itoh, Woosuck Shin, Maiko Nishibori
  • Publication number: 20130344124
    Abstract: An agent for virus inactivation capable of exhibiting inactivation action based on structural destruction such as degradation and decomposition against viruses, which comprises a monovalent copper compound such as cuprous oxide, cuprous sulfide, cuprous iodide, and cuprous chloride as an active ingredient, and a virus inactivation material, which contains the agent for virus inactivation on a surface of a substrate and/or inside of the substrate.
    Type: Application
    Filed: December 22, 2010
    Publication date: December 26, 2013
    Applicants: KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO
    Inventors: Kazuhito Hashimoto, Kayano Sunada, Masahiro Miyauchi, Xiaoqing Qiu, Yoshinobu Kubota, Hitoshi Ishiguro, Ryuichi Nakano, Jitsuo Kajioka, Yanyan Yao
  • Patent number: 8574610
    Abstract: An article or material is applied to the environment of the body of an animal (including humans) to provide both absorbency and antimicrobial activity. The article or material may comprise a water absorbent material; and a composition that reacts with water to produce molecular iodine. The composition provides a local concentration (in the water) of at least 10 parts per million iodine in water carried by the material (that is actual water supported by the water absorbent material) when the material has 5% by weight of water present in the water absorbent. The material may be a flowable material, or the article may be diaper, sanitary pad, bandage, adhesive pad or wrap for an animal.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: November 5, 2013
    Assignee: Biolargo Life Technologies, Inc.
    Inventor: Kenneth R. Code
  • Patent number: 8568759
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 29, 2013
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker
  • Publication number: 20130259582
    Abstract: A soil adherent pellet is detailed that includes a soluble calcium ion source, a magnesium ion source, or both present in an amount ranging from 15% to 99.9% by weight of a total dry weight of the pellet and a binder present in an amount ranging from 85% to 0.1% by weight of the total dry weight of the pellet. The pellet having a mean pellet domain size and a pellet surface. The soil adherent pellet is well suited for flocculating clay within the soil and delivery of an active ingredient with reduced runoff compared to prior art broadcast particles. A soil adherent pellet is also provided having a soluble calcium and/or magnesium ion source that is polycrystalline and carries therewith an active ingredient.
    Type: Application
    Filed: April 1, 2013
    Publication date: October 3, 2013
    Applicant: The Andersons, Inc.
    Inventors: Timothy D. Birthisel, Joseph Schalk, Joseph Schanski
  • Patent number: 8545863
    Abstract: Controlling insects of the superfamily of the Psylloidea in horticultural and/or agricultural crops, by using bicarbonate and carbonate salts.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: October 1, 2013
    Assignee: Globachem
    Inventor: Koen Quaghebeur
  • Patent number: 8501159
    Abstract: There are described nanoparticles of magnetic metal oxides employable in constructs consisting in polymer particles possibly also incorporating pharmacologically active substances.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: August 6, 2013
    Assignee: Colorobbia Italia S.p.A.
    Inventors: Giovanni Baldi, Daniele Bonacchi, Franco Innocenti, Giada Lorenzi, Marco Bitossi, Paolo Ferruti, Elisabetta Ranucci, Alfredo Ricci, Mauro Comes Franchini
  • Patent number: 8496952
    Abstract: The invention relates to a composition comprising a) silver and/or one or more silver compound and b) one or more biocidal active ingredients of the isothiazoline.
    Type: Grant
    Filed: February 20, 2008
    Date of Patent: July 30, 2013
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Uwe Falk, Michael Marcus Walter, Joerg Grohmann
  • Publication number: 20130189334
    Abstract: Composite materials comprising nanoparticles functionalized with metals are disclosed. The composite materials may be used in a variety of applications, including in coating compositions, cosmetic and pharmaceutical compositions, absorbent articles, and the like.
    Type: Application
    Filed: March 11, 2013
    Publication date: July 25, 2013
    Applicant: McNeil-PPC, Inc.
    Inventor: McNeil-PPC, Inc.
  • Patent number: 8486433
    Abstract: Present invention provides an antibacterial deodorant with antibacterial characteristics and high deodorizing capability. The antibacterial deodorant is inorganic oxide particles comprising a metal component and an inorganic oxide other than the metal component, the inorganic oxide includes titanium oxide and silica and/or zirconia, and the titanium oxide is crystalline titanium oxide. A content of the metal component in the inorganic oxide particles is in a range from 0.1 to 30% by weight as converted to an oxide thereof, and an average particle diameter of the inorganic oxide particle is in a range from 2 to 500 nm.
    Type: Grant
    Filed: April 29, 2005
    Date of Patent: July 16, 2013
    Assignee: JGC Catalysts and Chemicals Ltd.
    Inventors: Atsushi Tanaka, Tsuguo Koyanagi
  • Patent number: 8470359
    Abstract: A polymer and a method for its preparation are provided. The polymer comprises poly(lactide), poly(lactide/glycolide) or poly(lactic acid/glycolic acid) segments bonded by ester linkages to both ends of an alkanediol core unit. The polymer is for use in a controlled release formulation for a medicament, preferably leuprolide acetate. The controlled release formulation is administered to a patient as a subcutaneous depot of a flowable composition comprising the polymer, a biocompatible solvent, and the medicament. Controlled release formulations comprising the polymer release leuprolide for treatment of prostate cancer patients over periods of 3-6 months.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: June 25, 2013
    Assignee: QLT USA, Inc.
    Inventor: Richard L. Dunn
  • Patent number: 8399005
    Abstract: The present invention is directed to compositions comprising at least one nitric oxide donor and at least one second therapeutically active agent with antimicrobial or wound healing capability. In one embodiment, the nitric oxide donor is a nanoparticle which is designed to control for the amount and duration of release of nitric oxide. The nanoparticle may further comprise the additional therapeutically active agent. The composition is useful for enhancing wound healing and for treating and preventing microbial infection. In one embodiment, the composition is directed toward reducing oral bacteria or dental plaque. The combination of one or more nitric oxide donors and one or more additional therapeutically active agent results in unexpected synergistic effects, wherein both the antimicrobial efficacy of the nitric oxide and the antimicrobial or wound healing efficacy of the second therapeutically active agent are enhanced.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: March 19, 2013
    Assignee: University of North Carolina at Chapel Hill
    Inventors: Mark H. Schoenfisch, Evan M. Hetrick, Nathan A. Stasko, C. Bryce Johnson
  • Patent number: 8394396
    Abstract: Sol-gel inorganic porous particles are composed of an inorganic compound that provides an inorganic solid phase including an external particle surface. They also have a first set of pores wherein the pores have an average diameter of less than 100 nm and a second set of pores wherein the pores have an average diameter of at least 100 nm, which second set of pores contains stabilizing organic microgel particles. These inorganic porous particles are prepared using a first oil phase comprising a first water-immiscible aprotic solvent having a dielectric constant of less than 10 and having dissolved therein organic microgel particles. An aqueous phase comprising a polar solvent, an inorganic gel precursor, a catalyst, and a dispersing surfactant is neutralized to initiate condensation of the inorganic gel precursor. An oil-in-water emulsion is then formed with the organic microgel particles in the first oil phase, which is dispersed as first oil phase droplets in the aqueous phase.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: March 12, 2013
    Assignee: Eastman Kodak Company
    Inventors: Mary Christine Brick, Joseph Salvatore Sedita, Joan Kay Williams, Mridula Nair
  • Patent number: 8354110
    Abstract: The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: January 15, 2013
    Assignees: UTI Limited Partnership, The General Hospital Corporation
    Inventors: Pedro Santamaria, Anna Moore
  • Patent number: 8337867
    Abstract: The present invention relates to a method for the preparation of a new metal lactate powdery product and to the resulting product itself with new properties. The metal lactate powder of the present invention is made via spray-drying and has a higher flowability, is less sticky and dusty, has an improved dissolution rate and is very suited for tabletting purposes. The invention is also directed to product applications in which said spray-dried metal lactate product may be applied, wherein the metal is selected from zinc and magnesium.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: December 25, 2012
    Assignee: Purac Biochem B.V.
    Inventors: Marcus J. A. W. Vorage, Martijn Janissen
  • Patent number: 8337898
    Abstract: The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: December 25, 2012
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Sudipta Seal, Swanand D. Patil, Manas K. Haldar, Sanku Malik
  • Publication number: 20120316259
    Abstract: This invention relates to a process for the co-encapsulation of biocidally active ingredients in a clay mineral, the process comprising the step of bringing the clay mineral into contact with a biocidally active nitrogen compound that contains at least one hydrocarbon group with 6 to 20 carbon atoms, and at the same time or subsequently with at least one biocidally active compound selected from the group consisting of 2-n-octyl-4-isothiazoline-3-one, 3-iodopropenylbutyl-carbamate and tetrahis(hydroxymethyl)phosphonium sulfate. And the use of such encapsulated product in water based paints, coatings and varnishes.
    Type: Application
    Filed: February 15, 2011
    Publication date: December 13, 2012
    Applicant: CLARIANT S.A. BRAZIL
    Inventors: Antonio Pedro de Oliveira Filho, Wagner Claudio Da Silva, Manlio Gallotti, Alexandra Paschoalin Menezes, Karine Framesqui Righi, Marcia Regina Da Silva Rios
  • Publication number: 20120301533
    Abstract: Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers emulsions of hydrophobic polymers and surfactants.
    Type: Application
    Filed: June 20, 2012
    Publication date: November 29, 2012
    Inventors: Donald R. Uhlmann, Anoop Agrawal, Juan Carlos Lopez-Tonazzi, Ryan J. Reeser
  • Publication number: 20120294919
    Abstract: The invention is directed to an antimicrobial metal composite formed by vaporizing an antimicrobial metal or antimicrobial metal salt such as silver, copper or salts thereof using an plasma system and cooling the formed vapor in the presence of a fluidized gas of filler powder. Alternatively, the filler or a filler precursor is entrained with the antimicrobial metal or antimicrobial metal precursor and vaporized and then upon cooling the antimicrobial metal vapor and filler vapor condense to form the composite. The composite shows high antimicrobial activity and can be incorporated into or onto polymers, coatings, textiles, paper, gels (for example for wound care), lubricants, adhesives and cosmetics or pharmaceutical, especially medical devices.
    Type: Application
    Filed: May 14, 2012
    Publication date: November 22, 2012
    Applicant: BASF SE
    Inventors: Bingham Scott Jaynes, Matthew Edward Gande, Ryan James Fenton, Urs Leo Stadler, Marc Mamak, Sungyeun Choi
  • Publication number: 20120282316
    Abstract: Sol-gel inorganic porous particles are composed of an inorganic compound that provides an inorganic solid phase including an external particle surface. They also have a first set of pores wherein the pores have an average diameter of less than 100 nm and a second set of pores wherein the pores have an average diameter of at least 100 nm, which second set of pores contains stabilizing organic microgel particles. These inorganic porous particles are prepared using a first oil phase comprising a first water-immiscible aprotic solvent having a dielectric constant of less than 10 and having dissolved therein organic microgel particles. An aqueous phase comprising a polar solvent, an inorganic gel precursor, a catalyst, and a dispersing surfactant is neutralized to initiate condensation of the inorganic gel precursor. An oil-in-water emulsion is then formed with the organic microgel particles in the first oil phase, which is dispersed as first oil phase droplets in the aqueous phase.
    Type: Application
    Filed: May 5, 2011
    Publication date: November 8, 2012
    Inventors: Mary Christine Brick, Joseph Salvatore Sedita, Joan Kay Williams, Mridula Nair
  • Publication number: 20120263777
    Abstract: An environment-friendly porous bead-satellite nanoparticles composite which has excellent recovery and repeated usage performance and can be used as a catalyst, an antiviral agent, or an antimicrobial, and a fabrication method thereof are provided. The porous bead-satellite nanoparticles composite includes a porous bead, a molecule having a first end coupled to the surface of the porous bead and including a functional group at a second end, and satellite nanoparticles coupled to the functional group, wherein the porous bead may have a core-shell structure including a cluster core of nanoparticles and a porous bead shell covering the cluster core.
    Type: Application
    Filed: August 4, 2011
    Publication date: October 18, 2012
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kyoungja WOO, Hye Hun PARK, Wooyoung PARK
  • Patent number: 8287893
    Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: October 16, 2012
    Assignee: Sciessent LLC
    Inventor: Joseph J. Crudden