Coated Particulate Form (e.g., Liposome, Etc.) Patents (Class 424/417)
  • Patent number: 11051511
    Abstract: A bee attracting and bee tranquilizing composition has the form of an oil/water emulsion in aqueous phase, wherein the oil phase contains citral (3,7-dimethylocta-2,6-dienal), eugenol (4-allyl-2-methoxyphenol) and an oil carrier in an amount of 10% to 50% by weight of the composition, wherein the weight ratio of citral to eugenol is in a range from 1 to 10, and more preferably in a range from 1.7 to 5, and the aqueous phase contains a sweetener in an amount of 15% to 60% by weight based on the total weight of the aqueous phase. The sweetener is preferably selected from the group including: saccharose, fructose, glucose, sugar, inverted sugar syrup, maltose syrup and mixtures thereof. The invention also relates to methods and uses of such a composition for increasing the productivity of a crop area requiring bee pollination in agricultural and/or horticultural environments.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: July 6, 2021
    Assignee: ICB PHARMA SPOLKA JAWNA
    Inventors: Janusz Świȩtosławski, Wojciech Wieczorek
  • Patent number: 10918611
    Abstract: A method of forming an implant in a tissue can include: providing an injectable liquid composition comprising one or more precursors of a crosslinkable composition; injecting the injectable composition into the tissue at the rate of about 10-12000 injections per minute and/or at an amount of 1.0E-02 ml to 1.0E-16 ml per injection; and crosslinking the one or more precursors of the crosslinkable composition so as to form a crosslinked composition.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: February 16, 2021
    Assignee: PATHAK HOLDINGS LLC
    Inventor: Chandrashekhar P. Pathak
  • Patent number: 10893881
    Abstract: Systems and methods for treating a blood clot include a catheter to be inserted into a patient. The catheter is used to deliver low stability microbubbles toward the blood clot in the patient. A thrombolytic agent is delivered toward the blood clot, and ultrasonic energy is applied to the microbubbles to vibrate the microbubbles.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: January 19, 2021
    Assignee: University of Virginia Patent Foundation
    Inventors: Adam Joseph Dixon, John Alexander Hossack
  • Patent number: 10888625
    Abstract: A targeted drug delivery complex containing a particle, a targeting moiety electrostatically attached to the particle, and an active pharmaceutical ingredient attached to or dispersed or dissolved within the particle is provided. Also provided are pharmaceutical formulations containing a plurality of the complexes as well as methods for use in targeting an active pharmaceutical ingredient to a selected cell or tissue and production of such formulations.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: January 12, 2021
    Assignee: PARTICLE SCIENCES, INC.
    Inventors: Mark Mitchnick, Garry Gwozdz, Andrew Loxley
  • Patent number: 10822645
    Abstract: The present invention provides a method of amplifying an RNA molecule in a biological sample by reverse transcription PCR (RT-PCR), wherein the RT-PCR is carried out in a solution comprising a polyol, a serum albumin, a non-ionic surfactant and a reducing agent.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: November 3, 2020
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: Alexander Yarunin, Peter James Tatnell, Kathryn Louise Lamerton, Rebecca Fullerton
  • Patent number: 10799587
    Abstract: A composition for neutron capture therapy and a method of preparing the same are provided. The composition includes at least one nanodiamond particle and at least one neutron capture element, in which the at least one neutron capture element is embedded into the at least one nanodiamond particle by using an ion implantation system.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: October 13, 2020
    Inventors: Huan Niu, Chien Hsu Chen, Causon Ko-Chuan Jen
  • Patent number: 10791740
    Abstract: Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: October 6, 2020
    Assignee: The Curators of the University of Missouri
    Inventors: George W. Gokel, Michael R. Gokel, Saeedeh Negin, Mohit B. Patel
  • Patent number: 10543182
    Abstract: A method of forming a gel implant in tissue can include: providing an injectable composition configured for thermoreversible gel formation at about 37° C.; injecting the injectable composition into the tissue at the rate of about 10-12000 injections per minute; and forming a thermoreversible gel at about 37° C. from the injected injectable composition so as to form the gel implant. The injecting can be at an amount of 1.0E-02 ml to 1.0E-16 ml per needle per injection. The injecting can form an implant with area greater than or equal to 5 mm2. The injecting can be at a depth of 10 microns to 5 mm. The injectable composition can include a visualization agent, drug or other agent.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: January 28, 2020
    Assignee: Pathak Holdings LLC
    Inventor: Chandrashekhar P. Pathak
  • Patent number: 10463616
    Abstract: The instant invention is drawn to a hepatocyte targeted composition comprising insulin associated with a lipid construct comprising an amphipathic lipid and an extended amphipathic lipid that targets the construct to a receptor displayed by an hepatocyte. The composition can comprise a mixture of free insulin and insulin associated with the complex. The composition can be modified to protect insulin and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading insulin into the composition and recycling various components of the composition. Methods of treating individuals inflicted with diabetes.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: November 5, 2019
    Assignee: SDG, Inc.
    Inventors: John R. Lau, W. Blair Geho
  • Patent number: 10385311
    Abstract: A method of preparing a biological composite matrix system includes combining tissue microparticles with a curable medium. The tissue microparticles are formed by pulverizing tissue, sorting the pulverized tissue particles, and decellularizing the pulverized tissue particles. The tissue microparticles are then mixed with the curable medium and the resulting composite is cured to form a microparticle-medium composite matrix. The microparticle-medium composite matrix is compressed to increase the strength of the matrix and to increase the density of the microparticles to a predetermined density.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: August 20, 2019
    Assignee: Purdue Research Foundation
    Inventors: Corey Philip Neu, Tyler Anthony Novak
  • Patent number: 10220103
    Abstract: The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: March 5, 2019
    Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, The United States of America, as represented by the Secretary of Commerce
    Inventors: Gary Zabow, Stephen Dodd, Alan Koretsky, John Moreland
  • Patent number: 10215825
    Abstract: The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents. The invention also relates to a magnetic resonance sensor that alters it shape in response to a condition of an environment such that the condition may be detected.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: February 26, 2019
    Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, The United States of America, as represented by the Secretary of Commerce
    Inventors: Gary Zabow, Stephen Dodd, Alan Koretsky, John M Moreland
  • Patent number: 10188755
    Abstract: The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: January 29, 2019
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The United States of America, as represented by the Secretary of Commerce
    Inventors: Gary Zabow, Stephen Dodd, Alan Koretsky, John Moreland
  • Patent number: 9581597
    Abstract: Diagnostic tests for characterizing an individual's risk of developing or having a cardiovascular disease. In one embodiment the present diagnostic test comprises determining the level of myeloperoxidase (MPO) activity in a bodily sample obtained from the individual or test subject. In another embodiment, the diagnostic test comprises determining the level of MPO mass in a bodily sample obtained from the test subject. In another embodiment, the diagnostic test comprises determining the level of one or more select MPO-generated oxidation products in a bodily sample obtained from the test subject. The select MPO-generated oxidation products are dityrosine, nitrotyrosine, methionine sulphoxide or an MPO-generated lipid peroxidation products.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: February 28, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Stanley L. Hazen, Renliang Zhang
  • Patent number: 9497966
    Abstract: A pesticidal composition comprises a 3-(1H-pyrazol)pyridine compound of formula I or any agriculturally acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R9, R10, R12, x, n, and Q are as described herein. A method of controlling pests comprises applying the pesticidal composition near a population of pests.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: November 22, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Martin J. Walsh, Ann M. Buysse, Asako Kubota, Noormohamed M. Niyaz, Yu Zhang, Ricky Hunter, Tony K. Trullinger
  • Patent number: 9445997
    Abstract: The invention relates to microcapsule comprising at least one fat-soluble active substance selected from provitamins, vitamins and esters thereof, monounsaturated fatty acids, polyunsaturated fatty acids (PUFA's), carotenoids and benzoquinones embedded in a matrix comprising a hydrocolloid and optionally one or more other matrix components, wherein the content of active substance(s) is from 30 to 60% of total weight of the microcapsule, and wherein the ratio between said fat-soluble active substance(s) and said hydrocolloid is at least 4:1, as well as a process for preparing such microcapsules. The microcapsules of the invention may be used for the preparation of tablets, food products and other products including an active substance.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: September 20, 2016
    Assignee: BASF SE
    Inventors: Morten Mohr Hansen, Nina Musaeus, Carsten Lynggaard Hansen
  • Patent number: 9439941
    Abstract: The present invention provides methods, compositions, and kits wherein nanomaterials are used for inhibiting cancer stem cell division, colony formation, spheroid formation and self-renewal. The present invention also provides methods, compositions, and kits wherein nanomaterials are used for treating cancer, coating tumors, and inhibiting metastasis. The present invention also provides methods, compositions, and kits wherein nanomaterials are used for inducing cells to go into stasis. The present invention further provides methods for isolating tumors, inhibiting bleeding, and marking margins of tumors and organs during surgery with a nanomaterial.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: September 13, 2016
    Assignee: The University of Hong Kong
    Inventors: Rutledge Ellis-Behnke, Patrick Ming Tat Ling
  • Patent number: 9364493
    Abstract: The present invention relates to a new use of a known medicament. Specifically, the invention relates to methods and compositions for enhancing the therapeutic efficacy of a therapeutic agent by increasing the uptake of the therapeutic agent by target cells, and in particular relates to a pharmaceutical composition comprising a regulating agent of lipid raft/caveolae-dependent endocytic pathway and some therapeutic agents, such as anti-tumor agents. The invention also relates to a method for screening a regulating agent of lipid raft/caveolae-dependent endocytic pathway capable of enhancing the therapeutic efficacy of anti-tumor agents.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: June 14, 2016
    Assignees: Tsinghua University, Beijing Protgen LTD.
    Inventors: Yongzhang Luo, Yang Chen, Yan Fu, Lin Jia, Guodong Chang
  • Patent number: 9101548
    Abstract: A composition for modulating the immune response in a mammal comprising a pharmaceutically acceptable carrier solution and a plurality of biodegradable nanoparticles, wherein the nanoparticles comprise a targeting moiety that is able to bind selectively to the surface of a T lymphocyte cell and/or of a vascular endothelial cell and wherein the nanoparticles further comprise leukaemia inhibitory factor (LIF). Nanoparticle-mediated targeted delivery of LIF can be used a means to guide tolerogenesis in a patient and has immediate clinical application for recipients of organ grafts and also for patients suffering from autoimmune disease.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: August 11, 2015
    Inventors: Susan Marie Metcalfe, Tarek M. Fahmy
  • Publication number: 20150140056
    Abstract: The present disclosure relates to water dispersible granular pesticide compositions, and methods of making and using the compositions. The pesticide compositions include an inner layer including a first pesticide coated on to a substrate, and an outer layer comprising a second pesticide coated on the inner layer. The outer layer increases the water dispersibility of the granular composition, and protects the first pesticide against hydrolysis and photolysis.
    Type: Application
    Filed: January 23, 2015
    Publication date: May 21, 2015
    Inventors: Victor F. Man, Yvonne M. Killeen, Susan M. Viall
  • Patent number: 9012363
    Abstract: A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a second coating layer applied on the surface of the first coating layer. The first coating layer includes a wax composition having a biologically active ingredient incorporated therein and the second coating layer includes a polymeric composition. The granular agrochemical composition exhibits a controlled rate of release of the biologically active ingredient therefrom over a period greater than about 30 days from the date of initial exposure of the granular composition to moisture whereby essentially all of the biologically active ingredient incorporated in the wax material of the first coating layer is released from the granular composition before the water soluble portion of the granular core material is released from the granular composition.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: April 21, 2015
    Assignee: Everris International B.V.
    Inventors: Lonneke Jacoba van Boxtel-Verhoeven, Johannes Gijsbertus Antonius Terlingen, Petra Leonarda Hendrica Lunde-Vannuys
  • Patent number: 8992970
    Abstract: The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging entity. The present invention also provides methods of making the liposome compositions provided by the present invention.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: March 31, 2015
    Assignee: Merrimack Pharmaceuticals, Inc.
    Inventors: Keelung Hong, Daryl C. Drummond, Dmitri Kirpotin
  • Patent number: 8980292
    Abstract: A conditioner composition that increases the deposition and retention of benefit agent containing polyacrylate microcapsules onto hair. The conditioner composition is based on the combination of anionic charged polyacrylate microcapsules, deposition aids, conditioner agents, and a carrier.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: March 17, 2015
    Assignee: The Procter & Gamble Company
    Inventors: Jiten Odhavji Dihora, Jun Hasegawa
  • Patent number: 8980320
    Abstract: A film coating agent for a solid formulation includes a water-soluble cellulose derivative, swelling clay, a cationic surfactant, and a fatty acid, wherein mass ratio of the swelling clay to the water-soluble cellulose derivative is 2:8 to 8:2, and content of the cationic surfactant is not less than 0.5 equivalents and not more than 3.0 equivalents relative to a cation exchange equivalent of the swelling clay.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: March 17, 2015
    Assignee: Toray Industries, Inc.
    Inventors: Ryoji Yoshii, Yuki Hayashi, Yuki Fujisaki
  • Publication number: 20150033418
    Abstract: A first aspect of the invention is an agricultural composition comprising nanoparticles, an agrochemical active ingredient in the nanoparticles, and optionally (but in some embodiments preferably) a carrier for the nanoparticles. In some embodiments, the nanoparticles are viral particles or capsids, particularly plant viral particles or capsids. In some embodiments, the carrier comprises an inert or biodegradable carrier (e.g., a solid carrier) to which the nanoparticles are bound or in which the nanoparticles are suspended. In some embodiments, the carrier comprises inert or biodegradable polymer fibers.
    Type: Application
    Filed: April 16, 2013
    Publication date: January 29, 2015
    Inventors: Steven A. Lommel, Julie Willoughby, Richard Guenther
  • Patent number: 8920846
    Abstract: A microcapsule in which a liquid droplet is coated with a resin, wherein in the droplet, a pesticidally active solid ingredient is suspended in a compound of formula (I), wherein R represents a C1-C5 alkyl group, is useful as a formulation of a pesticidally active solid ingredient.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: December 30, 2014
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Naoki Tsuda, Mayuko Ozawa
  • Publication number: 20140370320
    Abstract: According to the present invention there is provided a preservative formulation for use in treating wood or other cellulosic formulations, said formulation comprising: at least one biocidal metal compound; at least one organic compound; and a carrier. Preferably, the preservative formulation is copper/(tebuconazole/propiconazole) in a ratio of about 1:3 w/w; the carrier is preferably aqueous or spirit-based.
    Type: Application
    Filed: December 19, 2012
    Publication date: December 18, 2014
    Inventors: David Humphrey, Brett Skewes
  • Patent number: 8906399
    Abstract: The invention relates to preparations, in particular plant-protective preparations which contain a mixture of at least two different active plant-protective substances, wherein a) at least one active substance is selected from a conazole group (active substance 1) and b) another active-plant protective substance (active substance 2) whose water solubility at a temperature of 20° C. is less than 20 g/l., c) at least one type of copolymer CP consisting of M monomers comprising ?) at least one type of monoethylenically unsaturated monomer M1 comprising at least one sulphonic acid group and ?) at least one type of neutral monoethylenically unsaturated monomer M2, wherein the quantitative ratio between the active substance 1 and the other active plant-protective substance 2 ranges from 1:10 to 10:1.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: December 9, 2014
    Assignee: BASF Aktiengesellschaft
    Inventors: Sebastian Koltzenburg, Peter Dombo, Günter Oetter, Christian Krüger, Wolfgang Schrof, Matthias Bratz
  • Publication number: 20140348893
    Abstract: The present invention describes a new non-compound based approach for insect and/or arachnid control. The present inventors have identified for the first time novel targets for RNAi, which can effectively control insect and/or arachnid pest populations. Accordingly, the invention provides both nucleotide and amino acid sequences for the novel targets. Also provided are RNA constructs including double stranded RNA regions for mediating RNAi in insects, DNA constructs, expression vectors, host cells and compositions for controlling insects and/or arachnids using RNAi. Finally, the invention also provides for the use of the constructs, vectors, host cells and compositions in control of insects and/or arachnids populations and suitable kits for use in an RNAi based method of controlling insect and/or arachnid pests.
    Type: Application
    Filed: May 27, 2014
    Publication date: November 27, 2014
    Applicant: DEVGEN NV
    Inventor: Titus Jan KALETTA
  • Patent number: 8895044
    Abstract: A method of protecting food or delaying the onset of food spoilage said method comprising applying a protective bioactive composition to the food or the packing or packaging in which the food is stored.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: November 25, 2014
    Assignee: Sciessent, LLC
    Inventor: Joseph J. Crudden
  • Patent number: 8858973
    Abstract: A composition comprising herbicidal mixtures of mesotrione impregnated into or coated on the surface of a granular substrate material such as a fertilizer granule and/or a solid inert carrier material is provided for use to control weeds in turfgrasses without causing damage to the grass and methods for the use thereof.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: October 14, 2014
    Assignee: OMS Investments, Inc.
    Inventor: Robert D. Baker
  • Patent number: 8846087
    Abstract: The present invention relates to an enteric coating formulation, as well as methods for preparing and using said enteric coating formulation. In particular, the invention relates to an enteric coating formulation that is made up of foodeous approved materials.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: September 30, 2014
    Assignee: Sensient Colors LLC
    Inventor: Vic Young
  • Patent number: 8815271
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes related thereto.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: August 26, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Maurice C. H. Yap, Ann M. Buysse, Daniel Knueppel, Yu Zhang, Negar Garizi, Noormohamed M. Niyaz, Christian T. Lowe, Ricky Hunter, Tony K. Trullinger, David A. Demeter, Dan Pernich, Carl Deamicis, Ronald Ross, Jr., Timothy C. Johnson
  • Patent number: 8808720
    Abstract: A product comprising microcapsules which themselves comprise (a) a polymeric shell; and (b) a core which comprises (i) a solid agrochemical dispersed in a matrix and (ii) a water-immiscible liquid characterized in that the matrix is distributed non-continuously throughout the water-immiscible liquid.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: August 19, 2014
    Assignee: Syngenta Limited
    Inventors: Patrick Joseph Mulqueen, Anne Waller, Julia Lynne Ramsay, Geoffrey William Smith
  • Patent number: 8765160
    Abstract: A method for the control of soil-dwelling pests and/or soil-borne diseases comprising treating a plant propagation material with an effective amount of the pesticidal composition and/or applying an effective amount of a pesticidal composition to a locus where control is desired, provided that the composition comprises, as active ingredient, one or more pesticides (A) having a water solubility of at most 100 ?g/liter, at 25° C. at neutral pH, and at least one formulation auxiliary, wherein the size of particles in the composition is in the range 3.60 ?m to 0.70 ?m at X90. Abamectin has been found to be particularly effective against nematode damage.
    Type: Grant
    Filed: September 18, 2006
    Date of Patent: July 1, 2014
    Assignee: Syngenta Crop Protection LLC
    Inventors: Frederique Guyon, Christoph Grimm
  • Patent number: 8759275
    Abstract: The present application relates to high efficiency particles and compositions, such as consumer products, comprising such high efficiency particles as well as processes for making and using such high efficiency particles and compositions comprising such high efficiency particles. Such high efficiency particles and compositions provide enhanced benefit agent delivery to a situs that is treated with such high efficiency particles and compositions.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: June 24, 2014
    Assignee: The Proctor & Gamble Company
    Inventors: Johan Smets, Pascale Claire Annick Vansteenwinckel, Yonas Gizaw, Frank Hulskotter, Dieter Boeckh, Hans-Joachim Haehnle
  • Publication number: 20140170200
    Abstract: Disclosed is pesticidal particulate composition of matter, the particles comprising active substances, which react upon contact inside a pest body, the reaction generating a gaseous product and/or heat which destroy the pest. Pesticidal preparations, methods and kits are also disclosed.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 19, 2014
    Applicant: ECOLOGIC TECHNOLOGIES LTD.
    Inventor: Ido OFEK
  • Publication number: 20140154298
    Abstract: The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging entity. The present invention also provides methods of making the liposome compositions provided by the present invention.
    Type: Application
    Filed: February 7, 2014
    Publication date: June 5, 2014
    Applicant: Merrimack Pharmaceuticals, Inc.
    Inventors: Keelung HONG, Daryl C. Drummond, Dmitri Kirpotin
  • Patent number: 8734816
    Abstract: Various exemplary embodiments provide protocell nanostructures and methods for constructing and using the protocell nanostructures. In one embodiment, the protocell nanostructures can include a core-shell structure including a porous particle core surrounded by a shell of lipid bilayer(s). The protocell can be internalized in a bioactive cell. Various cargo components, for example, drugs, can be loaded in and released from the porous particle core of the protocell(s) and then delivered within the bioactive cell.
    Type: Grant
    Filed: January 5, 2010
    Date of Patent: May 27, 2014
    Assignees: STC.UNM, Sandia Corporation
    Inventors: Juewen Liu, Jeffrey C. Brinker, Carlee Ashley, Eric C. Carnes
  • Publication number: 20140141137
    Abstract: The present invention provides an antimicrobial material in an encapsulated form, comprising (i) a core comprising an antimicrobial material and (ii) a shell of encapsulating material, wherein the shell of encapsulating material is impermeable to the antimicrobial material. The invention further provides a process for introducing an antimicrobial material, into a foodstuff comprising (i) providing the antimicrobial material in an encapsulated form comprising a core of antimicrobial material and shell of encapsulating material, and (ii) introducing encapsulated antimicrobial material into or onto the foodstuff.
    Type: Application
    Filed: November 16, 2012
    Publication date: May 22, 2014
    Applicant: Danisco A/S
    Inventors: Bob Coyne, John Faragher, Sébastien Gouin, Carsten Bjorn Hansen, Richard Ingram, Torben Isak, Linda Valerie Thomas, Kathryn Louise Tse
  • Patent number: 8716214
    Abstract: In a fragrance and/or aroma composition for the targeted release of fragrances and/or aromas in the form of a solid lipid nanoparticle (SLN) dispersion, in which lipid-based nanoparticles are present which are stabilized by an emulsifier monolayer, one or more membrane layers or other auxiliaries, the fragrances and/or aromas are included in the nanoparticles and/or in the emulsifier monolayer or the membrane layers.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: May 6, 2014
    Assignee: OTC GmbH
    Inventors: Gerd Dahms, Andreas Jung, Holger Seidel
  • Patent number: 8715704
    Abstract: The invention relates to a lure for attracting, and in some circumstances, killing dust mites, especially house dust mites. The lure comprises neryl formate and/or limonene and is usually arranged in powder form to allow it to be shaken over an area containing the mites. What about liquid that dries.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: May 6, 2014
    Assignees: London School of Hygiene & Tropical Medicine, Rothamsted Research Limited
    Inventors: Amanda Skelton, Mary Cameron, Michael Alexander Birkett, John Anthony Pickett
  • Patent number: 8685425
    Abstract: Microcapsules possessing Lewis acid-Lewis base salt walls incorporate water-immiscible materials, such as N,N-di-ethyl-m-toluamide (DEET), as a core component. Such microcapsules, or similar microcapsules incorporating other core components, may be made by emulsifying a water-immiscible core component in an aqueous solution of one wall-forming reactant, such as the Lewis base, and then mixing that solution with the other wall-forming reactant, such as the Lewis acid. Various adjuvants may be included with the core component to contribute additional characteristics, such as enhancement of a controlled release characteristic or improved mechanical stability.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: April 1, 2014
    Inventor: Tycho J. Speaker
  • Patent number: 8680121
    Abstract: This document discloses molecules having the following formula (Formula One) and processes related thereto.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: March 25, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Negar Garizi, Maurice C. H. Yap, Tony K. Trullinger, CaSandra Lee McLeod, Paul Renee LePlae, Jr., Timothy C. Johnson, Ricky Hunter, John F. Daeuble, Sr., Ann M. Buysse
  • Patent number: 8679515
    Abstract: Contaminants are filtered from a fluid flow stream and the filter is regenerated by a process including steps of: providing a filter material comprising both carbon and potassium iodide; passing a contaminated fluid stream in contact with the filter material; adsorbing contaminants from the fluid stream onto surfaces in the filter material; passing an electric current through the filter material with adsorbed contaminant thereon; disassociating contaminant from the surfaces of the filter material; and removing disassociated contaminant from the filter material by carrying away the disassociated contaminant in a fluid flow mass. Separately, a stable, active iodine solution is also provided for numerous deodorizing and disinfecting applications.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: March 25, 2014
    Assignee: Biolargo Life Technologies, Inc.
    Inventors: Kenneth R. Code, Joseph Provenzano
  • Patent number: 8673330
    Abstract: Insecticidal compositions suitable for use in preparation of insecticidal granular fertilizer and insecticidal formulations comprising a pyrethroid and a glycol present in a concentration of from 40.0% by weight to 99.0% by weight based upon the total weight of all components in the composition is disclosed.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: March 18, 2014
    Assignees: FMC Corporation, The Scotts Company LLC
    Inventors: Edward Kikta, Larry G. Faehl, Kim Watson, David R. Kilanowski, Robert Radabaugh, Coby L. Crane
  • Patent number: 8663671
    Abstract: Methods and compositions for producing hydrogel capsules enveloped with at least one coating layer is disclosed. The coating formulations deposited on the surface of the capsules can improve the physical integrity and the water-retention properties of the alginate beads. The coating formulations can be sequentially applied in various combinations to obtain desirable properties, such as improved physical integrity, mechanical strength, and low permeability, that can extend the shelf-life of the capsules when incorporated into various consumer products.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: March 4, 2014
    Assignee: Philip Morris USA Inc.
    Inventors: Georgios D. Karles, Daqing Wu, Shuzhong Zhuang
  • Patent number: 8647652
    Abstract: Methods for preparing silver colloids and silica-coated silver colloids are disclosed. The silver colloids may be prepared by heating a silver-containing solution, combining the heated silver-containing solution with an acid solution, and cooling the combined solutions to form a silver colloid containing silver particles. The silver particles in the silver colloid can further be coated with silica. A method for preparing antimicrobial coatings is also disclosed.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: February 11, 2014
    Assignee: Guardian Industries Corp.
    Inventor: Pramod K Sharma
  • Patent number: 8647653
    Abstract: A powdery composition, comprising: a) core-shell particles having a shell of hydrophobic or hydrophobized particles; and b) a carrier powder comprising a carrier and at least one of an at least partially water soluble liquid and a water reactive substrate reversibly bound to the carrier by at least one of the capillary action, absorption and adsorption is provided. The core-shell particles have a core, comprising: water; and 0 to 10 wt. % of a total core weight of a dissolved or emulsified material. The carrier comprises at least one material selected from the group consisting of silica, a silica-metal mixed oxide, phyllosilicate, starch, hollow glass spheres, nylon, sugar, cyclodextrines and polysaccharides, and a weight ratio of the carrier powder to the core-shell particles is from 1/1 to 1/9.
    Type: Grant
    Filed: November 26, 2010
    Date of Patent: February 11, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Jennifer C. Eng, Matthew Romaine, Christopher Proulx
  • Publication number: 20140004168
    Abstract: A biocidal glass composition for use in roofing applications can include glass doped with at least one biocidal agent that includes about 0.01 wt. % to about 50 wt. % of a total weight % of the biocidal glass composition. The biocidal glass composition can be included in a coating on a base particle of a roofing granule. Further included is a process of forming the roofing granule.
    Type: Application
    Filed: March 15, 2013
    Publication date: January 2, 2014
    Inventors: Pierre-Olivier Petit, Keith C. Hong, Gregory F. Jacobs, Kamila Plevacova