Gas Produced In Situ By Chemical Reaction Patents (Class 424/44)
  • Patent number: 11419805
    Abstract: A packaged aerosol foaming skin cleanser can include a multiphase skin cleansing composition, a low pressure foaming agent, and a package.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: August 23, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Karl Shiqing Wei, Jean Jianqun Zhao, Somil Manjul Shah, Wei Ji
  • Patent number: 11351275
    Abstract: Provided herein are magnetic resonance imaging (MRI) contrast agents comprising a compound having a structure represented by: Y—X—Z, wherein, X is: Fe(III) or Mn(II), and Y and Z are each independently selected from pyrophosphate and bisphosphonate (e.g., 1-hydroxybisphosphonate), or a pharmaceutically acceptable hydrate and/or salt thereof. Methods of use of the MRI contrast agent are also provided.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: June 7, 2022
    Assignee: Duke University
    Inventor: Christopher David Lascola
  • Patent number: 11291672
    Abstract: A stable oral spray formulation comprising a glucocorticoid together with other excipients is disclosed. In preferred embodiments, the spray formulation is used to treat neurological disorders such as ataxia by being sprayed in an effective dose into the mouth of a patient.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: April 5, 2022
    Assignee: GRACE THERAPEUTICS INC.
    Inventors: S. George Kottayil, Amresh Kumar, Prasanna Sunthankar, Vimal Kavuru
  • Patent number: 11219594
    Abstract: The present invention relates to effervescent compositions of Metformin and optionally other anti-diabetic agents and processes for preparation thereof. More particularly provides an effervescent composition comprising Metformin, an acid and a base such that the composition is free of affirmatively added binders and granulating solvents. The effervescent composition of the present invention has retained carbon dioxide content of at least 90% of the input blend.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: January 11, 2022
    Assignee: STEERLIFE INDIA PRIVATE LIMITED
    Inventors: Indu Bhushan, Vijay Kulkarni, Rakshith Shetty
  • Patent number: 11207255
    Abstract: A self-foaming cleansing compositions are provided. The self-foaming cleansing composition includes a) of one or more volatile silicone oil; b) one or more surfactants; and c) one or more polymers with suspending properties. The self-foaming cleaning composition is free of perfluoro compound.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: December 28, 2021
    Assignee: L'OREAL
    Inventors: Nicholas David Stebbins, Ryuji Hara, Susan Halpern Chirch
  • Patent number: 11141394
    Abstract: Provided is a nonaqueous carbon dioxide external preparation in single dosage form, the external preparation comprising a paste base, carbonate, an acid and/or a substance which produces an acid by hydrolysis, and alcohol. Merely by being applied onto skin, this external preparation is useful due to obtaining the effect of a specific action of carbon dioxide.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: October 12, 2021
    Inventor: Masaya Tanaka
  • Patent number: 11141364
    Abstract: Oral care compositions and methods for the same are provided herein. The oral care composition may include an orally acceptable vehicle, a peroxide whitening agent, and one or more gelling agents. The gelling agents may include a fatty acid. The gelling agents may be free or substantially free of fatty alcohols. The gelling agents may include at least one of palmitic acid, stearic acid, or mixtures thereof.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: October 12, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Guisheng Pan, Lin Fei, Suman Chopra
  • Patent number: 11058642
    Abstract: Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water. The tablets may comprise an active agent and excipient of almost any type, and about 0.1-about 0.5% by weight friability reducing agent. They exhibit a hardness of at least eighty percent (80%) of the same tablet prepared without the friability reducing agent.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: July 13, 2021
    Assignee: TOWER LABORATORIES LTD
    Inventors: Allen Rau, Donald Stadolnik, Melvin Corcino, Freddy Acosta
  • Patent number: 11020323
    Abstract: Aqueous solution of a transition and main group metal salt for use as conditioning agent in dental restoration therapy.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: June 1, 2021
    Assignee: Ivoclar Vivadent AG
    Inventors: Delphine Catel, Thorsten Bock
  • Patent number: 10987290
    Abstract: A packaged aerosol foaming skin cleanser can include a multiphase skin cleansing composition; a foaming agent including a hydrofluoroolefin, a hydrochlorofluoroolefin, or a combination thereof; and a package.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: April 27, 2021
    Assignee: The Procter and Gamble Company
    Inventors: Karl Shiqing Wei, Jean Jianqun Zhao, Somil Manjul Shah, Wei Ji
  • Patent number: 10959967
    Abstract: The present invention is directed to effervescent compositions comprising a basic amino acid.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: March 30, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Rajnish Kohli, Richard Scott Robinson, Ralph Peter Santarpia, III, James R. Brown, Richard J. Sullivan, Michael Prencipe
  • Patent number: 10952966
    Abstract: A solid pharmaceutical composition comprising a solid dispersion of a BCS Class II drug in a solid carrier/hydrophilic carrier; and a pH modifier. The solid carrier/hydrophilic carrier has a melting point of between about 40° C. to about 60° C. and an HLB value of between about 10 and about 18. The BCS Class II drug may be telmisartan.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: March 23, 2021
    Assignee: Gattefosse India Pvt. Ltd.
    Inventors: Nabil Farah, Sunil Bambarkar, Vincent Jannin, Chhanda Kapadia, Mangal Nagarsenker, Meenakshi Venkataraman, Megha Marwah
  • Patent number: 10863741
    Abstract: Herbicidal and pest-control compositions are variously described, including soaps as well as free fatty acids as active ingredients. The disclosed compositions may be constituted in a concentrated form, or the composition may be further diluted for application. Herbicidal compositions of the disclosure may be employed to selectively target unwanted vegetation without a systemic mode of action, and may be used to control a wide variety of unwanted plants, e.g., weeds, woody brush, trees, and/or grasses, in a locus that contains or is susceptible to emergence thereof.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: December 15, 2020
    Assignee: HOMS, LLC
    Inventor: Allen L. Jones, Jr.
  • Patent number: 10857098
    Abstract: The present disclosure is directed to floating gastroretentive dosage forms with prolonged gastric residence time. The disclosure also provides rapidly expanding sustained release or combined immediate release and sustained release formulations comprising drugs that require targeted release in the proximal gastrointestinal tract for maximum therapeutic benefit. The rapidly expanding floating gastroretentive dosage forms comprise a permeable elastic membrane providing desired characteristics for drug release and mechanical strength to maintain tablet integrity.
    Type: Grant
    Filed: May 6, 2020
    Date of Patent: December 8, 2020
    Assignee: KASHIV SPECIALTY PHARMACEUTICALS, LLC
    Inventors: Kanji Meghpara, Jaydeep Vaghashiya, Navnit H. Shah, Dipen Desai, Wantanee Phuapradit, Harpreet Kaur Sandhu, Siva Ram Kiran Vaka, Namdev B. Shelke, Ashish Chatterji
  • Patent number: 10744075
    Abstract: An oral care product, a whitening composition thereof, and methods for the same are disclosed therein. The oral care product includes an orally acceptable vehicle and the whitening composition. The whitening composition includes a whitening booster and a source of hydrogen peroxide. The whitening booster may include a salt of a monopersulfate.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: August 18, 2020
    Assignee: Colgate-Palmolive Company
    Inventors: Cajetan Dogo-Isonagie, Paloma Pimenta, Chun Huang
  • Patent number: 10639281
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: May 5, 2020
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Patent number: 10596135
    Abstract: The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: March 24, 2020
    Inventor: William A. Shaver
  • Patent number: 10485754
    Abstract: The process serves for preparing sodium ion-free X carbonate or hydrogencarbonate effervescent powder, such granules or such tablets. The active substances X, at least calcium carbonate, moistened with a small amount of alcohol and water, are mixed as powder with a small amount of lactobionic acid in a partial vacuum in a vacuum tank with continual pumping. As a result, the calcium salt (CaCO3) of the calcium in the surface layer of the powder particles reacts with the lactobionic acid, effervesces and releases a small amount of CO2. Consequently, the pressure in the vacuum tank rises and after the end of the effervescent reaction the internal pressure in the vacuum tank drops back to the starting value through the continual pumping. In so doing, the powder dries. After removal from the vacuum chamber an acid, preferably citric acid, as an effervescing agent is added, and subsequently the powder is electively pressed into tablets.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: November 26, 2019
    Assignee: BIOFAR LABORATORIES
    Inventor: Hanspeter Strobel
  • Patent number: 10378041
    Abstract: A latent effervescent body comprising a selective agent is disclosed. A method of using the latent effervescent body in a method to selectively enrich a target microorganism is also disclosed. The method comprises providing a sample, a culture medium, and the latent effervescent body. The method further comprises contacting the sample, the culture medium, and the latent effervescent body under conditions to facilitate growth of the target microorganism. The method further comprises releasing the selective agent from the latent effervescent body. Optionally, the method includes detecting a microorganism.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: August 13, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: Wensheng Xia, Patrick A. Mach, Joseph M. Beaurline, Jason W. Bjork, Jie J. Liu
  • Patent number: 10369093
    Abstract: The invention relates to a temperature-stable solution consisting of a) 0.1-10% by weight of at least one hexamidine salt, b) 40-95% by weight of an alkanediol having a C3 to C5 carbon chain and a C log P of ?0.2 to ?1.1, c) 5-60% by weight of water and d) one or more additives to adjust the pH of the solution to 3.0 to 6.0 inclusive, wherein the total amount of components a) to d) is 100% by weight.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: August 6, 2019
    Assignee: Minasolve Germany GmbH
    Inventors: Markus Nahrwold, Nadia Konaté
  • Patent number: 10258562
    Abstract: The present invention relates to a single-layer, effervescent tablet comprising a high level of aspirin and a reduced amount of alkaline substances, where the tablet rapidly dissolves in water.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: April 16, 2019
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Foyeke Opawale, Priya Nayak, Gerard Meisel
  • Patent number: 10231914
    Abstract: The embodiments herein discloses a composition and method for the synthesis of an effervescence producing tablet for reducing and eliminating a mouth odor and oral staining caused by ingested beverages and food. The method comprises mixing excipients, disintegrating agents, flavor and sweetener in a V-blender. The lubricant is added V-blender to obtain a mixture. The mixture is compressed on tablet press equipment with a round tooling. The tablets are packaged in a foil pouch. The “excipients” in the effervescent tablet composition are malic acid, sorbitol, potassium bi-carbonate, microcrystalline cellulose, sodium chloride, sodium carbonate and magnesium oxide. The malic acid react with potassium bicarbonate or sodium bicarbonate or sodium carbonate to form an effervescence reaction to induce tablet disintegration, provide a pleasant sensation in the mouth, and to clean a wine stain in the mouth.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: March 19, 2019
    Inventor: Lynette Batton
  • Patent number: 10172833
    Abstract: The invention is directed to sublingual spray formulations containing ondansetron, a pharmaceutically acceptable salt thereof, and a solvent consisting of ethanol and glycerin, suitable for administration to humans, and methods for treatment with sublingual formulations.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: January 8, 2019
    Assignee: INSYS DEVELOPMENT COMPANY, INC.
    Inventors: Kiran Kumar Vangara, Chandeshwari Shivani Chilampalli, Venkat R. Goskonda
  • Patent number: 10137065
    Abstract: The present invention relates to a cosmetic composition which is an antiperspirant and/or deodorant fluid composition to be applied to the human skin, the composition being a non-aluminum based fluid composition free from alcohols and oils, comprising sodium or potassium bicarbonate as the essential deodorizing agent.
    Type: Grant
    Filed: March 20, 2016
    Date of Patent: November 27, 2018
    Assignee: ODOURLESS SWEDEN AB
    Inventor: Thomas Odén
  • Patent number: 10085447
    Abstract: Methods and compositions for biofilm remediation are disclosed. Biofilm is reduced and removed from soiled surfaces by providing to a surface in need an effective amount of a composition comprising a biocidal surfactant and at least one organic solvent. According to the invention, the biofilm remediation compositions reduce and remove biofilm formation by administering a one-step cleaner and disinfectant. The biofilm remediation compositions are stable and effective in concentrated and diluted ready-to-use formulations comprising an anionic sulfated or sulfonated surfactant that is not an organocarboxylic acid, a sparingly soluble organic solvent and optionally a soluble organic solvent.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: October 2, 2018
    Assignee: Ecolab USA Inc.
    Inventors: Gregory G. Griese, Mark Levitt, Richard Staub, Stefanie Gilbreth
  • Patent number: 10046992
    Abstract: The present invention concerns a process for treating water and the use of calcium carbonate in such a process. In particular, the present invention is directed to a process for remineralization of water comprising the steps of providing feed water, and injecting gaseous carbon dioxide and a slurry into the feed water, wherein the slurry comprises micronized calcium carbonate.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: August 14, 2018
    Assignee: Omya International AG
    Inventors: Michael Skovby, Martine Poffet, Matthias Buri, René Vinzenz Blum
  • Patent number: 9993428
    Abstract: An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: June 12, 2018
    Assignee: Omya International AG
    Inventors: Daniel E. Gerard, Joachim Schoelkopf, Patrick A. C. Gane, Veronika Anna Eberle, Rainer Alles, Maxim Puchkov, Jörg Huwyler
  • Patent number: 9849137
    Abstract: A method of treating animals includes administering water soluble granules to an animal, where the water soluble granules include meloxicam, salt forming agent operable to form a meloxicam salt, a binder, and a carrier.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: December 26, 2017
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Stefan Henke, Martin A. Folger, Jens Lehmann, Diana C. Keilhofer, Hans-Juergen Kroff, Nina Herz
  • Patent number: 9687430
    Abstract: One aspect of the present invention relates to an effervescent tablet comprising a water-soluble lubricating agent, and a carbonated water cosmetic composition enabled to be used together therewith. One aspect of the present invention relates to an effervescent tablet comprising a crystalline #-hydroxy acid and a water-soluble lubricating agent, and a cosmetic composition using a skin toner for preventing the tablet from floating and allowing the tablet to rapidly form carbon dioxide gas in the cosmetic composition so as to maximize the visual effect and also the effect of carbon dioxide, thereby showing skin whitening, brightening and moisturizing effects and improving the pores.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: June 27, 2017
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Ju A Jung, Byung Ryol Paik, Chang Keun Lee, Lee Kyoung Kwon, Joon Ho Bae, Young So Kim
  • Patent number: 9585816
    Abstract: The embodiments herein discloses a composition and method for the synthesis of an effervescence producing tablet for reducing and eliminating a mouth odor and oral staining caused by ingested beverages and food. The method comprises mixing excipients, disintegrating agents, flavor and sweetener in a V-blender. The lubricant is added V-blender to obtain a mixture. The mixture is compressed on tablet press equipment with a round tooling. The tablets are packaged in a foil pouch. The “excipients” in the effervescent tablet composition are malic acid, sorbitol, potassium bi-carbonate, microcrystalline cellulose, sodium chloride, sodium carbonate and magnesium oxide. The malic acid react with potassium bicarbonate or sodium bicarbonate or sodium carbonate to form an effervescence reaction to induce tablet disintegration, provide a pleasant sensation in the mouth, and to clean a wine stain in the mouth.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: March 7, 2017
    Inventor: Lynette Batton
  • Patent number: 9566233
    Abstract: The invention is directed to sublingual spray formulations containing ondansetron or a pharmaceutically acceptable salt thereof and water. The invention is further directed to methods for treating or preventing nausea and emesis associated with cancer treatments by administering sublingual spray formulations containing ondansetron or a pharmaceutically acceptable salt thereof to a patient in need thereof.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: February 14, 2017
    Assignee: INSYS DEVELOPMENT COMPANY, INC.
    Inventors: Kiran Kumar Vangara, Chandeshwari Shivani Chilampalli, Venkat R. Goskonda
  • Patent number: 9516877
    Abstract: A method for preparing an antimicrobial alcoholic foam composition by combining two or more pre-mix compositions. A first pre-mix composition is primarily alcoholic comprises an alcohol, an acidic component, and a waxy component. A second pre-mix composition is primarily aqueous comprises water and a carbonate. An antimicrobial alcoholic foam composition that does not require added air or aerosol propellant is also provided.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 13, 2016
    Assignee: GOJO INDUSTRIES, INC.
    Inventors: Mitchell Jared Cohen, James Harvey Eberts, III, Evan David Hillman
  • Patent number: 9457204
    Abstract: This invention provides an effervescent solid form that dissolves in cold water quickly enough to not disappoint consumers yet not so quickly that the visual interest generated during the effervescent reaction is lost. This performance is achieved by forming effervescent particles that are dense enough to retard dissolution and small enough to not take too long to dissolve. The aim of this invention is to provide a beverage in solid effervescent form that takes between about 30 and about 120 seconds to dissolve in warm water. The granules may carry functional additives such as flavors, vitamins, minerals, sweeteners, colors and drugs. The granules may also be compounded of materials intended to provide relief from skin or topical discomfort, as in the form of a wash or bath additive. The granules may also be formulated to provide cleaning agents, such as ceramic cleaners and denture cleaners.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: October 4, 2016
    Assignee: Tower Laboratories, Ltd.
    Inventors: Allen Rau, Nicole Quinn, Donald Stadolnik, Eric Sterner
  • Patent number: 9271902
    Abstract: The invention provides a foamable composition for tooth bleaching which can be a one- or two-component system. The system has at least one peroxide compound, and at least one foaming agent. The composition can also contain at least one source of calcium, strontium and mixtures thereof, at least one de-sensitizing agent and at least one source of phosphate. The composition can produce a longer-lasting, collapsible foam structure with enhanced whitening action. The foamable composition can also be a one-component multi-phase system. A two-component composition can be packed in a two-compartment syringe. The syringe can also be fitted with a dispensing tip which may or may not have a static mixer.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: March 1, 2016
    Inventor: Martin S. Giniger
  • Patent number: 9242027
    Abstract: The first aspect of the present invention is directed to a method of producing a vascular network preform (VNP). This method involves forming a network of elongate fibers and at least one elongate structure from a sacrificial material. The diameter of the elongate structure is greater than that of the elongate fibers. The network of elongate fibers is placed in contact with at least one elongate structure either following or during forming the network of elongate fibers or forming the at least one elongate structure. A matrix is applied around the network of elongate fibers, in contact with the at least one elongate structure. The network of elongate fibers and elongate structure, within the matrix is sacrificed to form a preform. The resulting preform contains a vascular network of fine diameter tubes in contact with at least one elongate passage having a diameter greater than that of the fine diameter tubes. The resulting solid preform and methods of using it are also disclosed.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: January 26, 2016
    Assignee: Cornell University
    Inventors: Leon M. Bellan, Harold Craighead, Jason A. Spector
  • Publication number: 20150147279
    Abstract: The present invention relates to a process for preparing effervescent dosage forms comprising at least one antibiotic of cephalosporin group. The present invention also relates to effervescent formulations and preparations comprising antibiotics of second generation cephalosporin.
    Type: Application
    Filed: January 26, 2015
    Publication date: May 28, 2015
    Inventor: Mahmut BILGIC
  • Patent number: 9028854
    Abstract: A pesticidal composition comprising 4-phenoxyphenyl 2-(2-pyridyloxy)propyl ether; a hydrophobic organic solvent capable of dissolving 0.1-fold by weight of 4-phenoxyphenyl 2-(2-pyridyloxy)propyl ether at 0° C.; polyvinyl alcohol; a nonionic surfactant selected from the group consisting of alkoxylated castor oil, alkoxylated hydrogenated castor oil and alkoxylated hydrogenated castor oil fatty acid ester; and water, is excellent in storage stability.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: May 12, 2015
    Assignee: Sumitomo Chemical Company, Limited
    Inventor: Toshiyuki Tanedani
  • Publication number: 20150086488
    Abstract: The invention relates to a method for applying a cosmetic composition to hair. The method comprises the steps of removing a cosmetic composition from a sealed container, the composition comprising: a post-foaming emulsion comprising a weak acid, a weak base, a fatty acid, and a volatile buffering agent; a film forming agent; and an aqueous carrier; applying said composition to one or more eyelashes; and during or after said application to said one or more eyelashes, said cosmetic composition forms a foam, said foam resulting from the release of a gas, said gas being a reaction product of said post-foaming emulsion, and said reaction commencing after the evaporation of said volatile buffering agent, upon exposure of said cosmetic composition to atmospheric conditions.
    Type: Application
    Filed: September 23, 2014
    Publication date: March 26, 2015
    Inventors: John R. Castro, Arlene G. TING-JENULIS
  • Patent number: 8956653
    Abstract: The present invention relates to a process for preparing effervescent dosage forms comprising at least one antibiotic of cephalosporin group. The present invention also relates to effervescent formulations and preparations comprising antibiotics of second generation cephalosporin.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: February 17, 2015
    Inventor: Mahmut Bilgic
  • Patent number: 8916202
    Abstract: The present invention relates to a floating granule comprising a solid core, on which an active ingredient is supported and also comprising a compound which is capable of generating a gas discharge which is constituted by an alkaline agent, characterized in that it does not comprise an acid agent which is capable of generating a gas discharge.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: December 23, 2014
    Assignee: Debregeas et Associes Pharma
    Inventors: Christophe P Lebon, Pascal J Suplie
  • Patent number: 8852558
    Abstract: A composition for in situ formation and/or expansion of a polymer-based hemostatic agent to control bleeding includes a suitable amount of a polymer or polymer-forming component, hydrogen peroxide or chemical(s) capable of forming hydrogen peroxide, or a combination of both, and a decomposing agent for hydrogen peroxide. The decomposing agent includes an endogenously or exogenously supplied catalyst (other than catalase), or both, and/or the polymer or polymer-forming component.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: October 7, 2014
    Assignee: Materials Modification, Inc.
    Inventors: Joseph G. Montes, Krishnaswamy Kasthuri Rangan, Ramachandran Radhakrishnan, Tirumalai Srinivas Sudarshan
  • Publication number: 20140271849
    Abstract: The present disclosure provides an immediate release, abuse deterrent pharmaceutical solid dosage form comprising at least one functional score. In particular, the immediate release, abuse deterrent solid dosage form comprises at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: Siva N. Raman, Jae Han Park, Sunil K. Battu, Eric A. Burge, David W. Bogan
  • Patent number: 8828358
    Abstract: A composition for in situ formation of an artificial blockage to control bleeding includes a suitable amount of a polymer-forming component, a suitable amount of a crosslinking agent, hydrogen peroxide, and a decomposing agent for hydrogen peroxide. The decomposing agent includes exogenous or endogenous catalase, or both.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: September 9, 2014
    Assignee: Materials Modifications, Inc.
    Inventors: Joseph G. Montes, Krishnaswamy Kasthuri Rangan, Ramachandran Radhakrishnan, Tirumalai Srinivas Sudarshan
  • Publication number: 20140234228
    Abstract: Effervescent pharmaceutical compositions containing a high amount of N-acetylcysteine and a method of treating acetaminophen poisoning with effervescent pharmaceutical compositions containing a high amount of N-acetylcysteine are described.
    Type: Application
    Filed: April 29, 2014
    Publication date: August 21, 2014
    Applicant: ALPEX PHARMA S.A.
    Inventors: Federico STROPPOLO, Gabriele Granata, Shahbaz S. Ardalan
  • Patent number: 8808669
    Abstract: A gastroretentive, extended release composition which floats and swells at acidic pH prevalent in the stomach. The composition includes a pH dependent graft copolymer, a gellable polymer, a therapeutic agent, a gas generating system and pharmaceutically acceptable ingredients. The disclosed composition is useful to deliver the therapeutic agent within the stomach for an extended period of time.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: August 19, 2014
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ramesh Muthusamy, Mohan Gopalkrishna Kulkarni
  • Patent number: 8778396
    Abstract: This invention relates to an orally administrable, gastroretentive pharmaceutical dosage form which contains at least one pharmaceutically active ingredient and at least one polymeric adjuvant. The adjuvant serves to retain the dosage form in a selected region of the gastrointestinal tract for sufficient time for the pharmaceutically active ingredient to be released and absorbed. Ideally the dosage form will contain two or more pharmaceutically active ingredients which are delivered to different regions of the gastrointestinal tract.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: July 15, 2014
    Assignee: University of the Witwatersrand, Johannesburg
    Inventors: Viness Pillay, Yahya Choonara, Caragh Murphy, Sarashnee Moonisami
  • Patent number: 8765100
    Abstract: A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administerable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of additional pH adjusting substance in combination with the effervescent for promoting the absorption of drugs is also disclosed.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: July 1, 2014
    Assignee: Cephalon, Inc.
    Inventors: Jonathan D. Eichman, John Hontz, Rajendra K. Khankari, Sathasivan Indiran Pather, Joseph R. Robinson
  • Publication number: 20140170200
    Abstract: Disclosed is pesticidal particulate composition of matter, the particles comprising active substances, which react upon contact inside a pest body, the reaction generating a gaseous product and/or heat which destroy the pest. Pesticidal preparations, methods and kits are also disclosed.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 19, 2014
    Applicant: ECOLOGIC TECHNOLOGIES LTD.
    Inventor: Ido OFEK
  • Patent number: 8753611
    Abstract: A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: June 17, 2014
    Assignee: Cephalon, Inc.
    Inventors: Jonathan D. Eichman, John Hontz, Rajendra K. Khankari, Sathasivan Indiran Pather, Joseph R. Robinson
  • Patent number: 8728441
    Abstract: A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: May 20, 2014
    Assignee: Cephalon, Inc.
    Inventors: Jonathan D. Eichman, John Hontz, Rajendra K. Khankari, Sathasivan Indiran Pather, Joseph R. Robinson