Containing Polysaccharide (e.g., Sugar, Etc.) Patents (Class 424/479)
  • Patent number: 12059397
    Abstract: The invention relates to pharmaceutical compositions comprising calcium lactate as an active agent and a polysaccharide, polymer, lipid, or a combination thereof. The pharmaceutical compositions are useful treating cancer. The invention also relates to foods and nutrient compositions comprising calcium lactate.
    Type: Grant
    Filed: February 24, 2022
    Date of Patent: August 13, 2024
    Assignee: METIMEDI PHARMACEUTICALS CO., LTD.
    Inventors: Chong Hwan Chang, Keun-Yeong Jeong
  • Patent number: 12016955
    Abstract: A free-flowing solid pharmaceutical formulation comprising one or more active ingredients and a blend comprising sorbitol and liquid paraffin, a package containing the formulation, a process for the manufacture of the formulation and the use of the blend in the formulation.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: June 25, 2024
    Assignee: Ferring B.V.
    Inventors: Ganeshchandra Sonavane, Parag Lokhande, Pradeep Sethi, Tushar Wagh
  • Patent number: 11998639
    Abstract: The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
    Type: Grant
    Filed: September 2, 2022
    Date of Patent: June 4, 2024
    Assignee: AXSOME MALTA LTD.
    Inventors: Clark Patrick Allphin, Edwin Gerard Walsh
  • Patent number: 11696900
    Abstract: The invention discloses a composition exhibiting enhanced bioavailability comprising tri-molecular complex of a natural compound or a natural compound containing component, a divalent or tri-valent metal ion and a phospholipid embedded in natural matrix. The composition of the invention further exhibits a sustained release profile for the natural compound or natural compound containing component. The invention further discloses a process for manufacturing the tri-molecular complex containing composition.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: July 11, 2023
    Assignee: OLENE LIFE SCIENCES PRIVATE LIMITED
    Inventors: Vivek Anand Parachur, Somashekara Nirvanashetty
  • Patent number: 11439597
    Abstract: The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: September 13, 2022
    Assignee: Axsome Malta Ltd.
    Inventors: Clark Patrick Allphin, Edwin Gerard Walsh
  • Patent number: 11400065
    Abstract: Oral pharmaceutical compositions of sodium oxybate having improved pharmacokinetic properties when administered less than two hours after eating are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: August 2, 2022
    Assignee: Flamel Ireland Limited
    Inventors: Julien Grassot, Cendrine Grangeon, Jordan Dubow
  • Patent number: 11331287
    Abstract: An orally deliverable dosage system comprises (a) iron in a form of one or more physiologically acceptable iron grades, compounds and/or complexes; and (b) an agent to mitigate one or more gastrointestinal adverse effects of unabsorbed iron, said agent comprising one or both of a zinc component and a chelator component, said zinc component if present comprising one or more physiologically acceptable zinc compounds and/or complexes, and said chelator component if present comprising an ion-chelating compound formulated for release distal to the primary site of iron absorption in the duodenum.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: May 17, 2022
    Assignee: Balchem Corporation
    Inventor: Jonathan David Bortz
  • Patent number: 11208247
    Abstract: Melatonin tablets with a high concentration of citric acid are packaged in a blister package that enhances storage stability. Such a packaging material includes a blister film forming a cavity holding the tablet therein. The blister film includes a polyvinyl chloride (PVC) film having a thickness of 180 ?m to 270 ?m coated with a polyvinylidene chloride (PVDC) coating having a coating weight of 110 g/m2 to 130 g/m2. An aluminum foil lid closes the cavity and encapsulates the tablet within the blister film and lid. The lid has a thickness of 20 ?m to 30 ?m.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: December 28, 2021
    Assignee: Société des Produits Nestlé S.A.
    Inventors: Syed M. Shah, Daniel Hassan, Fred Hassan
  • Patent number: 11166917
    Abstract: The present invention relates to a novel directly compressible matrix for the production of tablets which disintegrate rapidly in the presence of moisture, in particular in the mouth.
    Type: Grant
    Filed: May 25, 2009
    Date of Patent: November 9, 2021
    Assignee: Merck Patent GmbH
    Inventors: Daniela Kleinwaechter, Guenter Moddelmog, Roberto Ognibene
  • Patent number: 11116711
    Abstract: A solid cosmetic composition contains cationic surfactant, a polyhydric C2-C6 alcohol, C8-C30 alcohol or C8-C30 carboxylic acid or salt and a starch fraction, a modified starch or a starch derivative and is used for hair care.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: September 14, 2021
    Assignee: HENKEL IP & HOLDING GMBH
    Inventors: Soeren Scheele, Manuela Mette, Petra Westphal, Thomas Schroeder
  • Patent number: 10646533
    Abstract: An absorption enhancer for polyphenol containing at least one kind of extract selected from the group consisting of an extract from Kochia scoparia (L.) Schrad., an extract from Acacia concinna, an extract from Sanicula europaea, an extract from Bupleurum rotundifolium, and a seed extract from Camellia sinensis, as an active ingredient.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: May 12, 2020
    Assignee: Kao Corporation
    Inventors: Shintaro Onishi, Shunsuke Ishii, Kojiro Hashizume
  • Patent number: 10596120
    Abstract: The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and/or a SGLT-2 inhibitor drug, and metformin XR, processes for the preparation thereof, and their use to treat certain diseases.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: March 24, 2020
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Masanori Ito, Kenji Egusa, Roman Messerschmid, Peter Schneider
  • Patent number: 10512656
    Abstract: The present invention relates to compositions and methods of treating lysosomal storage diseases and methods of using trehalose.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: December 24, 2019
    Assignee: Baylor College of Medicine
    Inventor: Marco Sardiello
  • Patent number: 10512609
    Abstract: The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: December 24, 2019
    Assignee: Jazz Pharmaceuticals Ireland Limited
    Inventors: Clark Patrick Allphin, Edwin Gerard Walsh
  • Patent number: 10398654
    Abstract: The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and/or a SGLT-2 inhibitor drug, and metformin XR, processes for the preparation thereof, and their use to treat certain diseases.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: September 3, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Masanori Ito, Kenji Egusa, Roman Messerschmid, Peter Schneider
  • Patent number: 10226417
    Abstract: Certain embodiments of the invention include medical materials and methods comprising a biodegradable hydrophilic hydrogel comprising dispersed lipophilic particles that comprise a therapeutic agent, wherein the lipophilic particles have a low water solubility in physiological saline at physiological temperature.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: March 12, 2019
    Inventors: Peter Jarrett, Rami El-Hayek, Amarpreet S. Sawhney, Sarah Guedez
  • Patent number: 10195151
    Abstract: The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: February 5, 2019
    Assignee: Jazz Pharmaceuticals International III Limited
    Inventors: Clark Patrick Allphin, Edwin Gerard Walsh
  • Patent number: 9956310
    Abstract: A tampon comprising an absorbent pledget and a time-lapse indicator associated therewith is provided. The time-lapse indicator includes a sensory material surrounded by, embedded in, covered by, or coated with a release-retarding material that protects the sensory material and prevents its release, until after a predetermined period of time has elapsed. The time-lapse indicator is located on or in the tampon or tampon removal string, or, optionally, the tampon packaging. After the time-lapse indicator is activated and a predetermined period of time has elapsed, the sensory material is released and alerts the user that it is time to change the tampon.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: May 1, 2018
    Inventor: Jeannette Martello
  • Patent number: 9795567
    Abstract: The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: October 24, 2017
    Assignee: JAZZ PHARMACEUTICALS, INC.
    Inventors: Andrea Marie Rourke, Maura Patricia Murphy, James Frederick Pfeiffer, Clark Patrick Allphin, Alya Kahn McGinlay
  • Patent number: 9376569
    Abstract: The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: June 28, 2016
    Assignee: ECOFLORA S.A.S.
    Inventors: Esteban Vargas Cano, Luis Fernando Echeverri Lopez, Juan Fernando Gil Romero, Edwin Andrés Correa Garcés, Sandra Patricia Zapata Porras
  • Patent number: 9157060
    Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: October 13, 2015
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Frances S. Ligler, André A. Adams, Michael Daniele
  • Publication number: 20150118307
    Abstract: Embodiments relate to Rifaximin polymorphic, salt, and hydrate forms, methods of producing polymorphic forms and to their use in medicinal preparations and to therapeutic methods using them.
    Type: Application
    Filed: May 27, 2014
    Publication date: April 30, 2015
    Applicant: SALIX PHARMACEUTICALS, LTD
    Inventors: Stephan D. Parent, Lisa Lynn McQueen, Patricia Andres, Paul Schields, Yiduo Wu, Fei Ding, Jared Peters Smit
  • Patent number: 9012521
    Abstract: An object of the present invention is to provide a gel containing pyrroloquinoline quinone that is capable of easily forming a gel near room temperature and is useful even in the food sector, and a method for producing the gel. According to the present invention, there is provided a gel containing pyrroloquinoline quinone that uses pyrroloquinoline quinone itself as a gelling agent and a method for producing the gel by adding a salt of pyrroloquinoline quinone to water and subsequently adjusting the temperature or the pH to reduce solubility.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: April 21, 2015
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Tsuyoshi Mikekado, Kazuto Ikemoto, Hajime Shimizu
  • Patent number: 8975228
    Abstract: Disclosed are methods and compositions related to the use of boswellic acids (such as acetyl-11-keto-?-boswellic acid, 11-keto-?-boswellic acid, ?-boswellic acid, acetyl-?-boswellic acid, 9,11-dehydro-?-boswellic acid, acetyl-9,11-dehydro-?-boswellic acid, ?-boswellic acid, acetyl-?-boswellic acid, 11-dehydro-?-boswellic acid, acetyl-9,11-dehydro-?-boswellic acid, lupeolic acid, acetyl lupeolic acid, 12-ursene-2-diketone, incensole, incensole acetate, a derivative, in particular an ester thereof, a pharmaceutically acceptable salt thereof, a combination thereof, or a preparation containing one or more of these compounds) for the human medical or veterinary prophylaxis and/or treatment of: a) damage to and/or inflammation of the islets of Langerhans and/or b) damage to the B-cells of the islets of Langerhans.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: March 10, 2015
    Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.
    Inventor: Hermann P. T. Ammon
  • Patent number: 8962018
    Abstract: The invention relates to a solid formulation for the oral administration of olanzapine that comprises a core of anhydrous olanzapine Form I or a pharmaceutically acceptable salt thereof and, optionally, pharmaceutically acceptable excipients, said core being coated with a functional polymer that acts as filmogenic agent. The method for obtaining it comprises: i) providing anhydrous olanzapine Form I or a salt thereof and, optionally, pharmaceutically acceptable excipients in solid form; ii) providing a functional polymer that acts as filmogenic agent; iii) preparing a dispersion of said functional polymer in an aqueous medium,—and applying the dispersion obtained in step iii) onto the solid form of step i).
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: February 24, 2015
    Assignee: Laboratorios Lesvi, S.L.
    Inventors: Ignacio Diez Martin, Carmen Ubeda Perez, Pablo Pablo Alba
  • Patent number: 8920840
    Abstract: The present invention relates to an enteric tablet with improved bioavailability, which is rapidly disintegrated after reaching the intestine to allow dissolution of the active ingredient, and which characteristically reduces the amount of talc to be used and is free of an alkali component.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: December 30, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Masafumi Misaki, Yuki Tsushima, Masahiro Niwa
  • Patent number: 8900575
    Abstract: The present invention comprises methods and compositions for the reduction of oxalate in humans. For example, the invention provides methods and compositions for the delivery of one or more oxalate-reducing enzymes embedded in particle compositions. The compositions of the present invention are suitable in methods of treatment or prevention of oxalate-related conditions including, but not limited to, hyperoxaluria, absorptive hyperoxaluria, enteric hyperoxaluria, primary hyperoxaluria, idiopathic calcium oxalate kidney stone disease (urolithiasis), vulvodynia, oxalosis associated with end-stage renal disease, cardiac conductance disorders, inflammatory bowel disease, Crohn's disease, ulcerative colitis, and patients who have undergone gastrointestinal surgery and bariatric surgery (surgery for obesity), and/or who have undergone antibiotic treatment.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: December 2, 2014
    Assignee: Oxthera Intellectual Property AB
    Inventors: Qingshan Li, Harmeet Sidhu
  • Publication number: 20140335174
    Abstract: The present invention provides a dry-coated tablet comprising: an inner core containing, as active ingredients, (a) tegafur, (b) gimeracil, and (c) oteracil potassium; and an outer shell.
    Type: Application
    Filed: May 24, 2012
    Publication date: November 13, 2014
    Applicant: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Takumi Okamoto, Takashi Yoshizawa, Yoshito Ohnishi
  • Publication number: 20140335180
    Abstract: The invention relates to a product for oral administration intended for a pet, comprising extracts of punica granatum (pomegranate). The invention is characterised in that the invention further comprises at least two additional antioxidant compounds chosen from:— soya isoflavone extracts;— L-carnitine; and— taurine.
    Type: Application
    Filed: November 8, 2012
    Publication date: November 13, 2014
    Applicant: VIRBAC SA
    Inventors: Patricia Monginoux, Hugues Gatto, Christian Karst, Ferdinand Rudolf Waldenberger
  • Publication number: 20140322324
    Abstract: Composition for use in treating bacterial infections, comprising a concentrate or an extract of origanum in combination with at least one concentrate or extract of another plant.
    Type: Application
    Filed: December 14, 2012
    Publication date: October 30, 2014
    Inventor: Georgios PANDALIS
  • Patent number: 8846089
    Abstract: A method is provided for producing a sugar-coated preparation including a solid composition containing a pharmacologically active ingredient and a sugar coating layer. The method comprises a step of forming the sugar coating layer with a sugar coating composition containing one or more sugar-alcohols selected from the group consisting of mannitol and erythritol and a polyvinyl alcohol-based resin. The sugar-coated preparation includes a solid composition containing a pharmacologically active ingredient and a sugar coating layer, wherein the sugar coating layer is made of a sugar coating composition containing one or more sugar-alcohols selected from the group consisting of mannitol and erythritol and a polyvinyl alcohol-based resin.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: September 30, 2014
    Assignee: Wakunaga Pharmaceutical Co., Ltd.
    Inventors: Yukoh Sakata, Masaharu Higuchi
  • Patent number: 8846087
    Abstract: The present invention relates to an enteric coating formulation, as well as methods for preparing and using said enteric coating formulation. In particular, the invention relates to an enteric coating formulation that is made up of foodeous approved materials.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: September 30, 2014
    Assignee: Sensient Colors LLC
    Inventor: Vic Young
  • Patent number: 8846088
    Abstract: A novel method for the preparation of a tablet comprising a calcium-containing compound, the method involves a melt granulation process by which a sugar alcohol is melted and embeds the calcium-containing compound so that a sufficient taste masking of the chalkiness is substantially achieved and an unpleasant mouth feel of the calcium-containing compound is substantially avoided, while at the same time obtaining a low tablet volume. The method of the invention is especially suitable for the manufacturing of tablets having a high load of a calcium-containing compound.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: September 30, 2014
    Assignee: Takeda Nycomed AS
    Inventors: Poul Egon Bertelsen, Peder Mohr Olsen, Carsten Martini Nielsen, Magnus Wilhelm Tolleshaug
  • Publication number: 20140255485
    Abstract: The present invention relates to collagen hydrolysate and the use thereof for treating and/or preventing cellulite.
    Type: Application
    Filed: May 20, 2014
    Publication date: September 11, 2014
    Applicant: GELITA AG
    Inventors: Hans-Ulrich FRECH, Steffen OESSER, Stephan HAUSMANNS
  • Publication number: 20140248351
    Abstract: The present invention relates to a granulate and a pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof and stabilizer, in particular to a pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof and sucrose, polyethylene glycol, cyclodextrin, and combinations thereof and to a process for its preparation. The granulate and the pharmaceutical composition are particularly useful as a medicament, especially for the treatment of urinary incontinence. The present invention relates to use of sucrose, polyethylene glycol, cyclodextrin, and combinations thereof for stabilizing fesoterodine or a salt or a solvate thereof in a pharmaceutical composition.
    Type: Application
    Filed: April 10, 2012
    Publication date: September 4, 2014
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Sara Cesar, Klemen Naversnik, Tijana Stanic-Ljubin
  • Patent number: 8815290
    Abstract: The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also relates to methods for manufacturing such gelatinous coated dosage forms.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: August 26, 2014
    Assignee: McNeil-PPC, Inc.
    Inventors: Roger A. Rinker, Nicholas J. Casale, James H. Comly, Brenda Pollock, Atul Ayer, Johan Geerke, Martin Costello, Dennis Wieand, Kishor Parekh
  • Patent number: 8796196
    Abstract: A process for producing anionic, nonionic, amphoteric or cationic derivatized polysaccharide products which demonstrate high clarity in surfactant-based compositions. The polysaccharide polymer is reacted for a sufficient time and at a sufficient temperature in the presence of water, caustic, and at least one surfactant. The polysaccharide polymer may optionally be reacted with an oxidizing agent, hydrolytic or proteolytic enzymes, molecular weight reducing agents and a cationizing agent and nonionic agent. The formed derivatized polysaccharide has a lower clarity in water than in an aqueous surfactant system. The derivatized polysaccharide product can be used in personal care and or household care products.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: August 5, 2014
    Assignee: Hercules Incorporated
    Inventors: Anita N. Chan, Louis Patrick Dziuk, Jr., Paquita Erazo-Majewicz, Jashawant J. Modi, M. Olaf Michelson
  • Patent number: 8778398
    Abstract: The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: July 15, 2014
    Assignee: Jazz Pharmaceuticals, Inc.
    Inventors: Andrea Marie Rourke, Maura Patricia Murphy, James Frederick Pfeiffer, Clark Patrick Allphin, Alya Khan McGinlay
  • Patent number: 8771735
    Abstract: The present invention provides a pharmaceutical composition, presented as a solid unit dosage form adapted for oral administration of sodium oxybate. The preferred unit dosage form is a tablet comprising a relatively high weight-percentage of sodium oxybate, in combination with a relatively small weight-percentage of total excipients. This permits the tablets to contain/deliver a pharmaceutically effective amount, e.g., about 0.5-1.5 g of sodium oxybate in each tablet with a delivery profile similar to that of the liquid form. The tablets are bioequivalent to the liquid form.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: July 8, 2014
    Assignee: Jazz Pharmaceuticals, Inc.
    Inventors: Andrea Rourke, Clark Allphin, Maura Murphy
  • Patent number: 8765180
    Abstract: A white coloring composition comprising calcium carbonate as a white pigment. It may be used in the manufacture of food and pharmaceutical products.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: July 1, 2014
    Assignee: Chr. Hansen A/S
    Inventor: Klaus Koehler
  • Patent number: 8741051
    Abstract: Composition (C) for coating ingestible solid forms, comprising, per 100% of its mass—from 10% to 90% of a graft copolymer of polyvinyl alcohol and of polyethers (Pi), and—from 10% to 90% by mass of an auxiliary coating agent, characterized in that a non-zero mass proportion of said auxiliary agent is polydextrose. Processes for the preparation and use thereof.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: June 3, 2014
    Assignee: Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC
    Inventors: Sandra Lefebvre, Gérard Trouve, Michel Malandain
  • Publication number: 20140147501
    Abstract: Controlled release, discrete, solid particles which contain an encapsulated and/or embedded component such as a heat sensitive or readily oxidizable pharmaceutically, biologically, or nutritionally active component are continuously produced without substantial destruction of the matrix material or encapsulant. A release-rate controlling component is incorporated into the matrix to control the rate of release of the encapsulant from the particles. The additional component may be a hydrophobic component or a high water binding capacity component for extending the release time. The plasticizable matrix material, such as starch, is admixed with at least one plasticizer, such as water, and at least one release-rate controlling component under low shear mixing conditions to plasticize the plasticizable material without substantially destroying the at least one plasticizable material and to obtain a substantially homogeneous plasticized mass.
    Type: Application
    Filed: January 29, 2014
    Publication date: May 29, 2014
    Applicant: GENERAL MILLS, INC.
    Inventor: Bernhard H. VAN LENGERICH
  • Publication number: 20140147500
    Abstract: Pharmaceutical compositions comprising one or more digestive enzymes and one or more gastrointestinal modulators of acid are provided. The one or more digestive enzymes may be coated, e.g., with a lipid. Also disclosed are methods for their use and controlled delivery in treating individuals with neurological, behavioral, infectious, or genetic diseases or conditions susceptible to treatment with digestive enzymes.
    Type: Application
    Filed: November 19, 2010
    Publication date: May 29, 2014
    Inventors: Joan M. Fallon, Matthew Heil, James F. Szigethy, James Fallon
  • Publication number: 20140147502
    Abstract: The present invention relates to an antibacterial agent and a hydrolysate made of at least one extract that has been produced by extraction using ethanol/water from dried plant material of: a) at least one of the plants selected from the group consisting of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Primula elatior (L.) Hill, and Gentiana lutea L.; and a mixture thereof; or b) a mixture of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Gentiana lutea L., and Rumicis herba; and subsequent removal of the ethanol/water extraction agent, wherein the hydrolysate can be obtained from the extract via hydrolytic treatment using a mineral acid. The hydrolyzates according to the invention show a pronounced antibacterial effect against germs relevant to the skin, ears, nose, and throat and respiratory systems.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 29, 2014
    Applicant: Bionorica AG
    Inventors: Guenther Bonn, Guenther Stecher, Michael A. Popp, Robert Mayer
  • Patent number: 8722089
    Abstract: The present invention features a method of making a coated tablet by dipping a core comprising an active agent into a coating liquid and drying said dipped core to form a outer-coating on the core, wherein the coating liquid contains at least one a starch having an amylose content of at least about 50 percent by weight of said starch.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: May 13, 2014
    Assignee: McNeil-PPC, Inc.
    Inventor: Jen-Chi Chen
  • Publication number: 20140127294
    Abstract: Provided is an oral solid preparation of a compound anti-tubercular drug, wherein the active ingredients are rifampicin, isoniazid, pyrazinamide and ethambutol hydrochloride. The compound oral solid preparation is a coated tablet with coated core or a coated three-layer tablet, wherein the two active ingredients rifampicin and isoniazid do not contact directly. The compound oral solid preparation not only improves the stability of the compound preparation, but also improves the bioavailability of rifampicin.
    Type: Application
    Filed: April 10, 2012
    Publication date: May 8, 2014
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Maojian Gu, Qilan Zheng, Chao Xu, Ning Li, Guixian Chen, Lan Zheng, Min Wang, Lintao Jiang
  • Patent number: 8715731
    Abstract: A process for reducing the intensity of the intrinsic bitter taste of a water soluble active which comprises dry mixing of said active with ?-cyclodextrin.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: May 6, 2014
    Assignee: ISP Investments Inc.
    Inventors: Rama Haldar, Dipan Ray, Deborah Tobia, Donald Koelmel, Sidney Etienne
  • Publication number: 20140099368
    Abstract: The invention provides novel hydroxystilbene-containing dosage forms, processes for producing these dosage forms and the use thereof for the treatment of menopausal symptoms in women, juvenile oligomenorrhea and dysmenorrhea, primary and secondary amenorrhea or endometritis.
    Type: Application
    Filed: July 24, 2013
    Publication date: April 10, 2014
    Inventors: Peter Heger, Reinhard Rettenberger, Carl-Friedrich Spaich
  • Patent number: 8679534
    Abstract: Controlled release oral solid dosage form for the reduction of serum cholesterol levels in humans include a drug comprising an alkyl ester of hydroxy substituted naphthalenes (e.g., lovastatin) and a controlled release carrier, such that the dosage form provides a mean time to maximum plasma concentration (Tmax) of the drug which occurs at about 10 to about 32 hours after oral administration on a once-a-day basis to human patients. The dosage form provides a therapeutically effective reduction in serum cholesterol levels. Methods of reducing serum cholesterol levels in humans are also disclosed.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: March 25, 2014
    Assignee: Andrx Labs, LLC
    Inventors: Chih-Ming Chen, Joseph Chou, David Wong
  • Publication number: 20130295179
    Abstract: The present application relates to compositions for use in a method of treating and/or preventing mental and behavioral disorders and/or improving mental health and cognitive functions in a subject, comprising: a) Docosahexaenoic acid (DHA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; b) Eicosapentaenoic acid (EPA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; c) ?-linolenic acid (GLA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; and at least a psychostimulant compound selected among methylphenidate HCl, atomoxetine, amphetamine, gamma-hydroxybutyrate, dextroamphetamine, sibutramine, methylenedioxymethamphetamine, and/or an anxiolytic compound selected among fluoxatine, sertraline, paroxetine, fluoroxamine, citralopram, venlafaxine, bupropion, nefazodone, and mirtazapine.
    Type: Application
    Filed: April 12, 2013
    Publication date: November 7, 2013
    Inventors: Christian TERREAUX, Eleonora HOMBERGER, Burkhard KRIWET, Eduardo BARRAGAN PEREZ