Fluorine Or Fluorine Compound Containing Patents (Class 424/52)
-
Publication number: 20120276023Abstract: Biguanide-preserved precipitated calcium carbonate oral care compositions and methods of manufacture thereof are disclosed.Type: ApplicationFiled: December 17, 2010Publication date: November 1, 2012Applicant: COLGATE-PALMOLIVE COMPANYInventors: Nilza Shimohirao, Odete Tieko Yamane, Abel Correia, Katrin Costa, Enzo Utima, Andre S. David
-
Patent number: 8298516Abstract: The present invention relates generally to an anti-calculus composition and method for treating subgingival calculus. The anti-calculus composition comprises a pyrophosphate and a tripolyphosphate in a pharmaceutically acceptable carrier. The composition may also comprise a fluoride providing compound.Type: GrantFiled: December 22, 2006Date of Patent: October 30, 2012Inventor: Douglas Anderson
-
Publication number: 20120263657Abstract: Disclosed are topical oral compositions comprising a safe and effective amount of an antimicrobial agent in admixture with a pharmaceutically acceptable carrier, the compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and in inhibiting the spread into the bloodstream of pathogenic oral bacteria, associated bacterial toxins and endotoxins, and resultant inflammatory cytokines and mediators. Also disclosed are methods of use of these topical antimicrobial oral compositions to reduce the risk of developing an oral bacteria-induced systemic disease and to promote whole body health in humans and other animals.Type: ApplicationFiled: June 26, 2012Publication date: October 18, 2012Inventors: Matthew Joseph Doyle, Stephen Joseph Hunter-Rinderle
-
Publication number: 20120258053Abstract: Generally regarded as safe (GRAS) dyes can be used as photosensitizing dyes in oral compositions to provide anti-bacterial and anti-inflammatory efficacy. Embodiments include oral care compositions including photosensitizing dyes, methods of making the compositions, methods of using the compositions, and kits containing the compositions and light emitting devices.Type: ApplicationFiled: December 20, 2010Publication date: October 11, 2012Applicant: COLGATE-PALMOLIVE COMPANYInventors: Madhusudan Patel, Rosa Paredes, Mahmoud Hassan, Thomas Boyd
-
Publication number: 20120251466Abstract: Disclosed herein are oral care compositions comprising a fluoride ion source and phosphate salts, and methods of making and using the same.Type: ApplicationFiled: December 17, 2010Publication date: October 4, 2012Applicant: COLGATE-PALMOLIVE COMPANYInventors: Shira Pilch, James Masters, Richard Sullivan
-
Patent number: 8278368Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a caseinate. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a caseinate and a hardenable resin or a water-dispersible, polymeric film former are also provided.Type: GrantFiled: November 7, 2005Date of Patent: October 2, 2012Assignee: 3M Innnovatve Properties CompanyInventors: Richard P. Rusin, Sumita B. Mitra, Kevin M. Cummings, Paul A. Burgio, Afshin Falsafi
-
Publication number: 20120237457Abstract: An anti-bacterial oral care composition and method for producing the same are disclosed. The composition comprises chitosan, organic acid, bioflavonoids and xylitol that are mixed together and can effectively inhibit the growth of bacteria in oral cavity, such as 99.9% of staphylococcus aureus, 99.9% of streptococcus mutans, 99.9% of candida albicans, thus reducing the occurrence of decayed tooth. Furthermore, no chemical preservative and anti-bacterial agent are added in the composition, reducing the damage to the oral mucosa and the health of the user.Type: ApplicationFiled: March 20, 2011Publication date: September 20, 2012Inventors: Shu-Cheng CHEN, Ho-Yi Tsai
-
Publication number: 20120219606Abstract: An oral care composition comprising fused silica, wherein at least 95% of the fused silica particles are spherical.Type: ApplicationFiled: May 3, 2012Publication date: August 30, 2012Inventors: George Endel Deckner, Arif Ali Baig, lain Allan Hughes, Eva Schneiderman, Lawrence Edward Dolan, Michael Jude Leblanc
-
Publication number: 20120213716Abstract: The present invention relates to a method for reducing or eliminating loss of minerals from the enamel and dental hypersensitivity against temperature changes, in particular when caused by the bleaching of teeth with products containing hydrogen peroxide or other oxidizing agents. After the bleaching process the teeth are treated with a calcium hydroxide containing solution, and subsequently the teeth are treated with a fluoride solution.Type: ApplicationFiled: January 10, 2012Publication date: August 23, 2012Inventor: Gunnar ROLLA
-
Publication number: 20120207686Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.Type: ApplicationFiled: October 29, 2009Publication date: August 16, 2012Applicant: Colgate-Palmolive CompanyInventors: Linh Fruge, Steven Wade Fisher, Michael Prencipe
-
Publication number: 20120189560Abstract: A beverage composition for strengthening and protecting tooth structure from decay and cavities, and for promoting dental health is provided. The beverage composition comprises one or more of about 0.5% to about 5% by weight of a polyol, about 0.005% to about 25% by weight of a natural and/or an artificial sweetener, about 1% to about 30% by weight of one or more vitamins and minerals, and their derivatives, a soluble source of fluoride ions containing about 0.1 ppm to about 1 ppm of fluoride ions, about 0.002% to about 0.008% of a water soluble casein, predetermined quantities of an herbal and/or fruit extract, a licorice root extract obtained, for example, from Glycyrrhiza uralensis, a non-mineral nutritional supplement, a flavoring agent, a preservative, a coloring agent, and a sufficient amount of a base composition, for example, water. The pH of the beverage composition is about 3.5 to about 7.0.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Inventor: Ammar A. Idlibi
-
Publication number: 20120189559Abstract: The present invention is directed to a carrageenan product comprising a semi-refined, alkali treated iota carrageenan wherein the semi-refined, alkali treated iota carrageenan has: (i) a viscosity of 18 cP to 83 cP, (ii) a particle size of at least 90% passing through a #100 US sieve mesh and at least 20% passing through a #230 US sieve mesh, and (iii) a fraction of sodium cations of at least 35%, wherein the fraction of sodium cations is determined by the weight of sodium cations divided by the sum of the weight of sodium cations and potassium cations. This invention is also directed to toothpaste compositions comprising the carrageenan product of the invention.Type: ApplicationFiled: August 6, 2010Publication date: July 26, 2012Applicant: FMC CORPORATIONInventors: Christopher J. Sewall, Vinayak B. Randive, Vijay K. Gadkari
-
Patent number: 8221725Abstract: An oral care composition comprising fused silica, wherein at least 25% of the fused silica particles are spherical.Type: GrantFiled: November 24, 2009Date of Patent: July 17, 2012Assignee: The Procter & Gamble CompanyInventors: George Endel Deckner, Arif Ali Baig, Iain Allan Hughes
-
Publication number: 20120175273Abstract: A toothpaste tablet having a tablet binder in an amount sufficient to form a tablet, a surfactant in amount sufficient to reduce surface tension and increase the rate of dissolution of the tablet in contact with saliva, a cranberry extract in an amount sufficient to reduce micro-adhesion of bacteria, an abrasive in an amount sufficient to mechanically remove debris from a tooth surface and debride plaque, and an artificial sweetener in an amount sufficient to adjust the flavor of the tablet when chewed by a user.Type: ApplicationFiled: January 7, 2011Publication date: July 12, 2012Inventors: Scott Jacobs, Allison J. LeGendre, David Wood
-
Publication number: 20120171128Abstract: Provided are dental cleaning compositions, methods of using and methods of using such compositions which minimize gum damage in the oral cavity. In one form, the dental cleaning composition includes a substantially stoichiometric ratio of one or more oxidizing agents to one or more reducing agents in one or more one or more orally acceptable carriers; where the substantially stoichiometric ratio of one or more oxidizing agents to one or more reducing agents is sufficient to neutralize the oxidizing agent in a subject oral cavity; and where the one or more oxidizing agents and one or more reducing agents are either co-dispensed or sequentially dispensed in the subject oral cavity.Type: ApplicationFiled: December 28, 2011Publication date: July 5, 2012Applicant: JR CHEM, LLCInventor: Jose E. Ramirez
-
Patent number: 8211408Abstract: An oral care composition comprising a fused silica abrasive and a fluoride source. The oral care composition may have a lower pH to aid in fluoride and/or active stability.Type: GrantFiled: November 24, 2009Date of Patent: July 3, 2012Assignee: The Proctor & Gamble CompanyInventors: Arif Ali Baig, George Endel Deckner, Iain Allan Hughes
-
Patent number: 8211409Abstract: An oral care composition comprising fused silica and an oxidizing agent.Type: GrantFiled: November 24, 2009Date of Patent: July 3, 2012Assignee: The Procter & Gamble CompanyInventors: Arif Ali Baig, George Endel Deckner, Iain Allan Hughes
-
Publication number: 20120164084Abstract: A flavored oral care composition and method of making same for preventing and/or treating bacterial, fungal or inflammatory diseases and conditions of the oral cavity may be in the form of a rinse, spray, or the like, and free of glycerin and free of castor oil and castor oil derivatives, incorporates a chlorine dioxide source, a phosphate buffer, a flavoring system containing a polyoxyethylene sorbitan ester (emulsifier/suspender) and flavoring agent, a sweetener and water. With the addition of a fluoride ion source, the composition may be used as an anticaries agent.Type: ApplicationFiled: May 25, 2011Publication date: June 28, 2012Applicant: MICROPURE, INC.Inventors: James L. Ratcliff, Karen Black, William E. Cooley, Esmeralda Ann Garcia
-
Patent number: 8206689Abstract: The invention provides an oral preparation or a chewing gum comprising an organic acid and/or inorganic acid and a fluoride ion supplying compound, wherein a light scattering layer is formed inside enamel of the teeth when the oral preparation or the chewing gum is applied to teeth. An internal tooth colored layer in the enamel is masked by the light scattering layer, and a white appearance is imparted to the teeth.Type: GrantFiled: October 31, 2003Date of Patent: June 26, 2012Assignee: Kao CorporationInventors: Kazuhiko Kato, Yoshinori Murakami, Yoshiyuki Muroi, Manabu Tonomura, Mitsuyoshi Kashiwagi
-
Publication number: 20120148506Abstract: A polyantiseptic antimicrobial pharmaceutical composition for oral use, for the hygiene and treatment of oral diseases of bacterial, mycotic or viral etiology, for over-the-counter sale, without contraindications. The composition does not contain phenolic or, chlorophenolic compounds, and consists of a mixture of hydrogen peroxide, eugenol, natural camphor, zinc sulphate, sodium fluoride, xylitol, cetylpyridinium chloride and excipients. The formulation is used to deodorise, disinfect, astringe and soothe inflammation of the oral area, avoids the neoformation of bacterial plaque, prevents tooth cavities, inhibits the formation of dental tartar, improves the resistance of teeth to cavities, and treats and prevents oral aphthous ulcers.Type: ApplicationFiled: August 19, 2010Publication date: June 14, 2012Inventor: Tomas Bernardo Galvan Gonzalez
-
Patent number: 8197797Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.Type: GrantFiled: April 12, 2005Date of Patent: June 12, 2012Assignee: Mineral Science Co.Inventor: Brian Giles
-
Publication number: 20120121669Abstract: Oral care compositions comprising a capsules comprising flavoring and/or one or more active ingredients, and/or flavours, said capsules distributed in an orally acceptable vehicle or carrier.Type: ApplicationFiled: August 11, 2009Publication date: May 17, 2012Applicant: Colgate-Palmolive CompanyInventors: Jose Eder Fontana, Edilberto Lemos, Henrique Jorge Sousa Sales, Marcia Pereira
-
Publication number: 20120114718Abstract: A method of repairing weakened teeth, including combining a first predetermined amount of an inorganic calcium source with a second predetermined amount of an organic material to define a mixture, placing the mixture in a milling vessel operationally connected to a planetary mill, introducing milling media into the milling vessel, milling the mixture to impart sufficient kinetic energy to break down the organic and inorganic materials into substantially smaller intermediate particles and fuse the intermediate particles together to yield functionalized molecules having both organic and inorganic chemical characteristics, combining a functionalized calcium phosphate/organic compound with a fluoridated formulation to define a hybrid system, and applying the hybrid system to the weakened teeth.Type: ApplicationFiled: May 11, 2011Publication date: May 10, 2012Inventor: Robert L. Karlinsey
-
Publication number: 20120114567Abstract: Oral composition comprising a Camellia extract of semi-oxidized tissue from a member of the genus Camellia and an enhancing agent.Type: ApplicationFiled: January 20, 2012Publication date: May 10, 2012Applicant: Colgate-Palmolive CompanyInventors: Thomas J. Boyd, Abdul Gaffar, David Viscio
-
Publication number: 20120093743Abstract: A system and method for preventing tooth decay comprises steps or acts of adding a small dose of fluoride to a carbonated or sugar-containing beverage to prevent tooth decay by its being drunk by a user.Type: ApplicationFiled: October 13, 2010Publication date: April 19, 2012Inventor: Henry M. Clayman
-
Publication number: 20120087960Abstract: A cationic compatible metal oxide and oral care compositions containing the metal oxide are disclosed. Preferably, the oral care compositions contain a cationic compatable metal oxide and a cationic ingredient, such as for example, a cationic antibacterial agent such as cetyl pyridinium chloride (“CPC”). The cationic compatible metal oxide, e.g. silica, comprise metal oxide particles having a subtantially negative surface charge and a vitamin deposited onto or reacted with the surface of the metal oxide particles in an amount sufficient to provide a substantially positive surface charge on the metal oxide particle. Processes for making and using the vitamin modified metal oxide in oral care compositions are also disclosed.Type: ApplicationFiled: June 16, 2010Publication date: April 12, 2012Inventor: James George Miller
-
Publication number: 20120082628Abstract: Oral care compositions having improved taste, said compositions comprising: a carrier material; from about 0.001 to about 10%, by weight of the composition, of an oral care component selected from metal salts, antimicrobial agents, bad breath reduction agents, bleaching agents, surfactants, or a combination thereof; and from about 0.Type: ApplicationFiled: September 29, 2011Publication date: April 5, 2012Inventors: John Christian Haught, Christine Marie Cahen, Koti Tatachar Sreekishna, Wenzhu Zhao, Yakang Lin, Cathy Renee Schinaman
-
Publication number: 20120070478Abstract: The invention relates to personal care products containing multilayer films with decorative layers and may impart a noticeable color change. The invention is applicable in products including type toothpaste, soaps, and other products until diluted with water (or saliva).Type: ApplicationFiled: April 2, 2009Publication date: March 22, 2012Applicant: Colgate-Palmolive CompanyInventors: Thomas Boyd, Guisheng Pan, Harsh M. Trivedi, Wei Wang, Nora Lin
-
Patent number: 8128911Abstract: An abrasive dentifrice composition which effects enhanced antiplaque and breath freshening properties which comprises an orally acceptable vehicle containing a combination of a safe and effective amount of an antibacterial agent and at least two enzyme ingredients.Type: GrantFiled: May 10, 2002Date of Patent: March 6, 2012Assignee: Colgate-Palmolive CompanyInventors: Lori H. Szeles, Xiaoyan Liu, Malcolm Williams, M. Teresa R. Carale, Michael Prencipe, James G. Masters
-
Publication number: 20120052025Abstract: A stabilized topical composition comprising a borinic acid derivative, e.g., a borinic ester.Type: ApplicationFiled: June 3, 2010Publication date: March 1, 2012Applicant: Colgate-Palmolive CompanyInventors: Venda Porter, Andre Morgan, Stanislav Jaracz, Jennifer Gronlund, Guofeng Xu, Donghui Wu, Michael Prencipe, Ravi Subramanyam
-
Publication number: 20120045402Abstract: Disclosed are dentifrice compositions comprising an orally acceptable vehicle and at least one source of metal ions in a polymer matrix, the metal being selected from zinc, stannous, copper or combinations thereof, the at least one source of metal ions comprising from 10 to 75 wt % of the total weight of the polymer matrix and the at least one source of metal ions, and wherein the dentifrice composition comprises less than 10 wt % water based on the total weight of the dentifrice composition. Also disclosed is a method of stabilizing at least one source of metal ions in a dentifrice compositions.Type: ApplicationFiled: May 25, 2010Publication date: February 23, 2012Applicant: Colgate-Palmolive CompanyInventors: Andre Morgan, Venda Porter, Melissa Martinetti, Michael Prencipe
-
Publication number: 20120045400Abstract: The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity.Type: ApplicationFiled: May 18, 2009Publication date: February 23, 2012Applicant: Colgate-Palmolive CompanyInventors: Andrew Nowak, Shira Pilch, Jim Masters
-
Publication number: 20120039820Abstract: A composition such as an oral care composition comprising an antibacterial system comprising 4-isopropyl-3-methyl phenol (IPMP), a source of zinc ions and an anionic surface active agent is described.Type: ApplicationFiled: April 1, 2010Publication date: February 16, 2012Applicant: Glaxo Group LimitedInventors: Alison Axe, David Bradshaw
-
Publication number: 20120034280Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.Type: ApplicationFiled: August 5, 2011Publication date: February 9, 2012Applicant: Research Foundation of State University of New YorkInventors: Marvin Cohen, Susanne Cohen, Bob Flynn
-
Publication number: 20120027696Abstract: The invention encompasses compositions and methods for treating and modifying surfaces of teeth, which compositions include calcium and magnesium containing silicates or silica, cationic polymer modified silica or combinations thereof. The composition when applied to the teeth or a tooth surface deposit on such surfaces to repair acid damaged enamel and prevent further erosion of a tooth surface.Type: ApplicationFiled: April 1, 2009Publication date: February 2, 2012Applicant: Colgate-Palmolive CompanyInventors: Shira Pilch, James Gerard Masters
-
Publication number: 20120027829Abstract: A dentin mineralizing agent comprising tetracalcium phosphate particles (A) and an alkali metal salt of phosphoric acid (B), wherein the dentin mineralizing agent contains the tetracalcium phosphate particles (A) in an amount of 1 to 80 parts by weight relative to 100 parts by weight of the whole amount of the dentin mineralizing agent, and the blended amount of the alkali metal salt of phosphoric acid (B) relative to 100 parts by weight of the tetracalcium phosphate particles (A) is 1 to 100 parts by weight. Thus is provided a dentin mineralizing agent by which a dense HAp is formed on a dentin surface and HAp is deposited to a deep portion of a dentinal tubule, so that it can close the dentinal tubule.Type: ApplicationFiled: March 26, 2010Publication date: February 2, 2012Applicant: Kuraray Medical Inc.Inventors: Tadashi Hashimoto, Mariko Sugiura, Shumei Ishihara, Mitsunobu Kawashima, Koichi Okada
-
Publication number: 20120020898Abstract: The invention encompasses non-aqueous dentifrice compositions containing a bioacceptable and bioactive glass with improved mouth-feel, foam, and product stability. More particularly, the invention encompasses non-aqueous compositions including combinations including carrageenan and/or carboxymethylcellulose gums, glycerin, ethylene oxide/propylene oxide copolymers, and a bioactive glass and methods of use the compositions in an oral care product, for example, a whitening tooth-paste, for hypersensitive teeth.Type: ApplicationFiled: April 1, 2010Publication date: January 26, 2012Applicant: Colgate-Palmolive CompanyInventors: Prakasarao Mandadi, Suman K. Chopra, Lynette Zaidel, Michael Prencipe
-
Publication number: 20120020899Abstract: The invention encompasses oral care compositions comprising one or more active component and one or more adhesive polymers, which cause the active component to adhere to the tooth surface. In certain embodiments the active agent is an occlusion agent. The invention also encompasses methods of treating the teeth or a teeth surface with an active agent. In certain embodiments, the invention encompasses treating the teeth with an occlusion agent to prevent or alleviate tooth sensitivity.Type: ApplicationFiled: April 1, 2010Publication date: January 26, 2012Applicant: Colgate-Palmolive CompanyInventors: Lynette Zaidel, Michael Precipe, Suman K. Chopra
-
Publication number: 20120021031Abstract: The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long-tem release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.Type: ApplicationFiled: April 1, 2010Publication date: January 26, 2012Applicant: Colgate-Palmolive CompanyInventors: Suman K. Chopra, Lynette Zaidel, Michael Prencipe
-
Publication number: 20120014883Abstract: Compositions containing one or more derivatives of essential oil compounds for use in personal care compositions, such as compositions for oral, throat and skin care are disclosed. These derivatives include acetals of parent essential oil aldehydes and ketones; esters or ethers of parent essential oil alcohols and phenolics; and esters of parent essential oil acids. Examples of parent essential oil aldehydes and ketones include citral, cinnamic aldehyde, ?-anisaldehyde, vanillin, ethyl vanillin, heliotropin, carvone, and menthone. Examples of parent essential oil alcohols and phenolics include thymol, eugenol, isoeugenol, dihydroeugenol, carvacrol, carveol, geraniol, nerol, vanillyl alcohol, heliotropyl alcohol, ?-anisyl alcohol, cinnamyl alcohol and ?-ionol. Examples of parent essential oil acids include ?-anisic acid, cinnamic acid, vanillic acid and geranic acid.Type: ApplicationFiled: July 19, 2011Publication date: January 19, 2012Inventors: Douglas Craig Scott, Lowell Alan Sanker, Robert Leslie Swaine, JR.
-
Publication number: 20110318283Abstract: Use as antibacterial agents of the oral cavity of formulations comprising zinc compounds having formula: [R—(OCH2CH2)n—OSO3?].½Zn2+??(I) wherein R is a linear or branched C6-C20 saturated or unsaturated aliphatic chain, n is an integer in the range zero-20.Type: ApplicationFiled: June 16, 2011Publication date: December 29, 2011Applicant: FARMACEUTICI DOTT. CICCARELLI S.P.A.Inventors: Marco PASETTI, Roberto CERINI, Antonela ANTONINI, Maria Rosaria FEDELE
-
Publication number: 20110318282Abstract: A human oral care composition, includes safe and effective amounts of the fluoride ion and stabilized chlorine dioxide, that may take the form of a paste, gel, rinse, spray, powder, varnish or similar that reduces demineralization and promotes remineralization of teeth. The method includes the topical application of the composition to the human oral cavity (including but not limited to the teeth, gingiva, and tongue), preferably at least once daily, to enhance the anti-caries effect of fluoride by released chlorine dioxido compromising any biofilm present.Type: ApplicationFiled: December 22, 2009Publication date: December 29, 2011Applicant: MICROPURE, INC.Inventors: James L. Ratcliff, Lee E. Kirsch, Jessica K. Ward Dykstra, William E. Cooley, Gary Armitage, Robert Ashley, Esmeralda Ann Garcia
-
Patent number: 8080235Abstract: Protein kinase A reporters useful for obtaining measurements of protein kinase A activity with high spatial and temporal resolution can be used in high throughput assays to identify potentially therapeutic compounds.Type: GrantFiled: October 26, 2006Date of Patent: December 20, 2011Assignee: The Johns Hopkins UniversityInventors: Jin Zhang, Qiang Ni, Michael David Allen
-
Patent number: 8071077Abstract: Antiplaque oral compositions are provided that contain an orally acceptable carrier and an antibacterial effective amount of the compound of formula (I). In various embodiments, the compositions contain from about 0.001% to about 10% by weight of the compound of formula (I).Type: GrantFiled: November 28, 2005Date of Patent: December 6, 2011Assignee: Colgate-Palmolive CompanyInventors: Ravi Subramanyam, Prem Sreenivasan
-
Patent number: 8071076Abstract: An oral lubricant having usefulness for alleviating the symptoms of dry mouth and preventing accumulation of dental stains based on a polyvinyl alcohol polymer containing composition in an orally acceptable carrier or vehicle. The invention relates generally to an oral composition having a function in lubricating the mouth and preventing the formation of stains on the surfaces of the teeth. The active ingredients of the composition are a polyvinyl alcohol, a metal chelating agent, lipophilic vitamin, surface active material and a phenolic anti microbial agent with anti-inflammatory properties.Type: GrantFiled: November 21, 2002Date of Patent: December 6, 2011Assignee: Oral Health Clinical Services LLCInventor: Salim A. Nathoo
-
Publication number: 20110293541Abstract: Embodiments of a method of making an oral care composition comprise providing plant material comprising silica, burning the plant material to remove organic impurities from the plant source material, removing inorganic impurities from the burnt plant material by hydrolyzing with an aqueous acid solution, separating the silica from the burnt plant material, and incorporating the separated silica into an oral care composition.Type: ApplicationFiled: May 25, 2011Publication date: December 1, 2011Inventors: John Christian Haught, Arif Ali Baig, George Endel Deckner, Ian Allan Hughes
-
Publication number: 20110286941Abstract: The present application relates to a combination of two separately stored and jointly used compositions, which are suitable for the combat and the prevention of caries. Thereby, each of the two compositions respectively comprises a fluorine compound. Further, one composition comprises an acidic pH-value, while the other composition comprises a basic pH-value.Type: ApplicationFiled: November 17, 2009Publication date: November 24, 2011Inventor: Klaus-Uwe Busch
-
Publication number: 20110287074Abstract: Disclosed herein are a variety of applications for an antimicrobial agent. The antimicrobial agent comprises a silanol containing molecule, the silanol containing molecule comprising silanols (R1R2R3SiOH), siloxanediols HO(R1R2SiO)nH, siloxanols HO(R1R2SiO)nSiR1R2R3 or combinations thereof, where R1, R2 and R3 are selected from alkyl or fluoroalkyl moieties having 1 to 4 carbon atoms, vinyl or aryl groups and n is less than about 6.Type: ApplicationFiled: May 24, 2011Publication date: November 24, 2011Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.Inventors: Liwen Jin, Ronald Howard Baney
-
Patent number: 8052961Abstract: Disclosed are compounds having the structure: wherein R1a and R1b are independently H, alkyl, F, or fluoroalkyl; wherein R2a, R2b, R2a?, and R2b? are independently H, alkyl, F, fluoroalkyl, aryl, or alkenyl; wherein R3 is OH, alkoxyl, NH2, alkylamino, or dialkylamino; wherein R4a and R4b are independently H, alkyl, acyl, or alkyloxycarbonyl; wherein R11, R12, R13, R21, R22, and R23 are independently H, alkyl, F, or fluoroalkyl; and wherein C0, C1, C2 and C2? are independently chiral or achiral. Also disclosed are processes for making a fluorinated ?-amino acid comprising the steps of: providing a diol; treating the diol with a thionyl halide with oxidative workup; reacting the product with an azide salt to yield an azido group; oxidizing the product to yield a carboxyl group; and reducing the azido group to yield an amino group.Type: GrantFiled: September 14, 2007Date of Patent: November 8, 2011Assignee: University of Utah FoundationInventors: Bruce (Yihua) Yu, Zhong-Xing Jiang
-
Publication number: 20110268672Abstract: Compositions containing ferrate(VI) are disclosed. Also, methods are disclosed that utilize ferrate(VI).Type: ApplicationFiled: March 10, 2008Publication date: November 3, 2011Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Bruce F. Monzyk, Michael J. Murphy, Chad Cucksey, F. Michael von Fahnestock, Andrew J. Savage, David N. Clark