Abstract: A oral care composition comprising a triple polymer system and a source of fluoride ions for combating (i.e. helping to prevent, inhibit and/or treat) dental erosion and/or tooth wear is described. Such compositions are also of use in combating dental caries.

Abstract: The present invention is directed to the use of antibiotics for preparing topical oral antibiotic formulations for treating and/or preventing black-line stains. This invention is further directed to a method of treating and/or preventing black-line stains comprising administration of a topical oral antibiotic formulation. The invention is additionally directed to a topical oral antibiotic formulation for use in treating and/or preventing black-line stains.

Abstract: A cariostatic food is provided. The food comprises: (1) (i) a phosphorylated saccharide calcium salt; or (ii) a combination of a phosphorylated saccharide salt other than a phosphorylated saccharide calcium salt or a phosphorylated saccharide, and a water-soluble calcium salt other than a phosphorylated saccharide calcium salt; (2) a fluoride; and (3) a polyphenol; wherein the phosphorylated saccharide is composed of a saccharide moiety and phosphate group(s); the content of the component (1) in the food is in an amount suitable to make the calcium concentration in saliva in the oral cavity to be 1 mM to 12 mM when the food exists in the oral cavity; and the content of fluoride in the food is in an amount suitable to make the fluoride concentration in saliva in the oral cavity to be 0.2 ppm to 100 ppm when the food exists in the oral cavity.

Abstract: Calcium phosphate particles are described comprising a surface treatment wherein the surface treatment comprises at least one sugar alcohol, at least one glycerophosphoric acid compound, or mixture thereof. Also described are various oral care compositions comprising surface treated calcium phosphate particles and methods of surface treating calcium phosphate particles.

Abstract: The present invention relates to oral care compositions comprising stannous ions, a mint-type flavor oil, a protectant component that prevents generation of off odor and off taste in the composition, and orally acceptable carriers. The mint-type oils include peppermint, spearmint and corn mint. Suitable protectant components include copper salts and carbonyl compounds such as ascorbic acid; cis-jasmone; 2,5-dimethyl-4-hydroxy-3(2H)-furanone; 5-ethyl-3-hydroxy-4-methyl-2(5H)-furanone; vanillin; ethyl vanillin; anisaldehyde; 3,4-methylenedioxybenzaldehyde; 3,4-dimethoxybenzaldehyde; 4-hydroxybenzaldehyde; 2-methyoxybenzaldehyde; 4-methoxybenzaldehyde; benzaldehyde; cinnamaldehyde (3-phenyl-2-propenal); hexyl cinnamaldehyde; ?-methyl cinnamaldehyde; ortho-methoxy cinnamaldehyde; ?-amyl cinnamaldehyde; and combinations thereof. The oral care composition may be a dentifrice.

Abstract: A dentifrice composition comprising a source of fluoride ions and from 0.01-1.5% w/w of a xanthan gum, from 0.01-1.5% w/w of a polyacrylic acid, from 0.01-2.0% w/w of a carageenan gum and a thickening silica and wherein the composition has a pH of between 5.5 and 6.5.

Abstract: The present invention is directed to methods and compositions comprising a basic amino acid, e.g., arginine, for the treatment of dry mouth.

Abstract: This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent.

Abstract: Compositions and methods for targeting agents to hard tissue are provided comprising A method includes administering to a subject a composition comp?sing micelles, the micelles comp?sing at least one amphiphilic block copolymer linked to at least one tooth targeting moiety The composition further includes at least one encapsulated compound and is provided in a pharmaceutically acceptable carrier.

Abstract: The present invention relates generally to an anti-calculus composition and method for treating subgingival calculus. The anti-calculus composition comprises a pyrophosphate and a tripolyphosphate in a pharmaceutically acceptable carrier. The composition may also comprise a fluoride providing compound.

Abstract: Embodiments of the present invention include compositions, methods, and systems for providing an effective and efficient treatment varnish for teeth. For example, embodiments of the present invention provide a treatment varnish that comprises one or more polymers and/or copolymers that are soluble in biocompatible solvents, such as ethanol. The polymers and/or copolymers are nontoxic and form a substantially clear film that adheres effectively to teeth during treatment, but also is easily removed from teeth once the treatment is complete.

Abstract: An enhancing composition comprising a solvent and a base compound creates an alkaline environment for activating peroxide whiteners and accelerating the formation of free radicals from the peroxide to effect the oxidation of organic molecules causing staining of the dentition. In one embodiment, potassium hydroxide is dissolved in water to form a strongly alkaline liquid. A surfactant may also be included to clean the surfaces of the user's teeth in advance of application of the whitening composition. A peroxide may be added to the enhancing composition to provide a tooth whitening. Other additives for taste, texture, viscosity, and other oral care or oral hygiene purposes may also be included in the enhancing composition. The enhancing composition may be used for advance application to the dentition before a whitening compound. In addition, a rinse may be used after the whitening composition to neutralize the alkaline environment.

Abstract: This, intention relates to methods of assessing the biofiora of the mouth and of providing appropriate treatment utilizing a basic amino acid in accordance with the assessment.

Abstract: The present invention primarily concerns teeth cleaning compounds containing menthol for use with a toothbrush, preferably tooth pastes, tooth crèmes, tooth cleaning gels or tooth powders. Such a tooth cleaning compound according to the invention contains menthol and a quantity, for masking the bitterness of the menthol, of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the following formula (Ia), in particular of the following formula (Ib), i.e. L-menthane carboxylic acid-N-(4-methoxyphenyl)-amide. The present invention also concerns the use of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the formulas (Ia) or (preferably) (Ib) to mask the bitter taste of menthol in a teeth cleaning compound. The present invention also concerns a method for dissolving menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) in a teeth cleaning compound and a method for masking the bitterness of menthol in a teeth cleaning compound.

Abstract: To provide a tooth coating composition capable of maintaining dental caries preventing effects of CPP-ACP, such as recalcification effect and demineralization-inhibiting effect, for a long period of time, a tooth coating composition is made not to contain water, but to include (a) 0.5 to 20% by weight of a casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP) and/or a casein phosphopeptide-amorphous calcium fluoride phosphate complex (CPP-ACFP), (b) 5 to 70% by weight of a coating film-forming polymer, (c) 5 to 70% by weight of an organic solvent selected so as to contain alcohol, (d) 0.01 to 10% by weight of a fluorine compound, and (e) 0.1 to 20% by weight of a thickener, the tooth coating composition being used by coating on a tooth.

Abstract: A two-component whitening system has a de-sensitizing effect as well as re-mineralizing capability. The system may be an unfoamed, a foamed or a foamable composition. The system has a first component with at least one peroxide compound, at least one source of phosphate and at least one gelling agent; and a second component with at least one source of calcium, strontium and/or mixtures thereof. The second component may also contain at least one gelling agent, and the composition maybe present as a foam or is foamable. The composition may be packed in a two-compartment syringe.

Abstract: This invention relates to compositions comprising a basic amino acid free or salt form and a soluble carbonate or bicarbonate salt.

Abstract: The present invention relates to the use of a protein selected from one or more of casein, ovalbumin, whey protein and soy protein for combating (i.e. helping to prevent, inhibit and/or treat) dental erosion and/or tooth wear caused by subsequent exposure to acid.

Abstract: Peptides have been identified that bind to oral surfaces such as teeth and gums. Peptide based oral care reagents have been created by couple such peptides to oral care benefit agents such as whiteners.

Abstract: An oral composition comprising an active component and an adhesive film forming component comprising bleached shellac and shellac wax for the treatment of teeth.

Abstract: The present invention relates to a single phase oral care composition comprising: a. a stannous salt delivering a stannous ion; b. a potassium salt delivering a potassium ion wherein the potassium salt is selected from potassium nitrate, potassium gluconate, potassium citrate, potassium chloride, potassium tartrate, potassium bicarbonate, and mixtures thereof; c. a chelant; d. a fluoride ion source; and e. less than 0.01% of an alkyl sulphate or an alkyl ethoxylate sulphate; wherein the oral care composition provides a soluble fluoride ion level of greater than 50% of the total fluoride ion. The composition of the invention has been found to allow prolonged contact between stannous ion and nitrate ion in a single dentifrice without toxic effects or insoluble products. The invention further provides for the maintenance of an efficacious fluoride ion level.

Abstract: The present invention relates to a single phase oral care composition comprising: a. a stannous salt b. a potassium salt c. a chelant d. monofluorophosphate (MFP). The composition of the invention has been found to allow prolonged contact between stannous ion and nitrate ion in a single dentifrice without toxic effects or insoluble products. The invention further provides for the maintenance of an efficacious fluoride ion level.

Abstract: The present invention relates to a single phase oral care composition comprising: g. a stannous salt delivering a stannous ion; h. a potassium salt delivering a potassium ion; i. a chelant; j. a fluoride ion source; k. less than 0.01% of an alkyl sulphate or an alkyl ethoxylate sulphate; and l. a surfactant selected from a cationic, an amphoteric surfactant, a nonionic surfactant or mixtures thereof; wherein the oral care composition provides a soluble fluoride ion level of greater than 50% of the total fluoride ion. The composition of the invention has been found to allow prolonged contact between stannous ion and nitrate ion in a single dentifrice without toxic effects or insoluble products. The invention further provides for the maintenance of an efficacious fluoride ion level.

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with a soluble calcium salt, and to methods of using and of making such compositions.

Abstract: The invention relates to a water-soluble composition comprising a water miscible liquid and water-soluble particles, the water-soluble composition being essentially free of water. The composition can be used e.g. as dental composition, cleaning agent, polishing agent, tongue surface cleaning agent or peeling agent.

Abstract: This invention relates to methods of treating early enamel lesions comprising applying an effective amount of a basic amino acid in free or salt form, together with fluoride to a patient in need thereof.

Abstract: The present invention describes oral care compositions comprising certain surface-coated inorganic oxides and their use for treating dentine hypersensitivity.

Abstract: The present invention provides oral instruments comprising a basic amino acid, to compositions for making such instruments, and to methods of making and using such instruments.

Abstract: The present invention provides tooth-whitening compositions comprising a bleaching agent and a baste amino acid, together with devices for application thereof, and methods of use therefor.

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form and a low dosage of fluoride and to methods of using such compositions.

Abstract: The use of an oral care composition comprising certain alkyl phosphates is described for combating dental erosion and tooth wear.

Abstract: The invention relates to a particulate composition comprising: c) a particulate source of stannous chloride; d) and silicon dioxide (also referred to as hydrated silica or silica). The invention further relates to a method for improving the flowability of particulate stannous chloride by admixing silica with it. The composition of the invention has been found to give improved flow properties to stannous chloride when compared to the absence of an anti-caking agent, as assessed via methods of powder characterisation detailed in the European Pharmacopoeia.

Abstract: A tooth-cleaning formulation which contains Himalaya salt in an unadulterated and also non-heat-treated form and/or Sango coral, with the Himalaya salt being used as a direct natural raw material and not being heated and sterilized itself.

Abstract: The present invention is directed to compositions comprising at least one nitric oxide donor and at least one second therapeutically active agent with antimicrobial or wound healing capability. In one embodiment, the nitric oxide donor is a nanoparticle which is designed to control for the amount and duration of release of nitric oxide. The nanoparticle may further comprise the additional therapeutically active agent. The composition is useful for enhancing wound healing and for treating and preventing microbial infection. In one embodiment, the composition is directed toward reducing oral bacteria or dental plaque. The combination of one or more nitric oxide donors and one or more additional therapeutically active agent results in unexpected synergistic effects, wherein both the antimicrobial efficacy of the nitric oxide and the antimicrobial or wound healing efficacy of the second therapeutically active agent are enhanced.

Abstract: Disclosed are a liquid type dentifrice composition primarily containing silver particles which is drawn out in foam state when used to brush teeth to prevent the liquid dentifrice from flowing down during tooth-brushing, resulting in effective and convenient tooth-brushing function and exhibit bactericidal action and protect mouth and teeth from periodontal disease and other mouth diseases because of original properties of silver ingredients in the dentifrice composition; and, in addition to, a mousse type dentifrice formulation using the same that improves aesthetic property and product quality thereof. The inventive dentifrice composition primarily containing silver particles useful for mouthwash comprises: at least one surfactant selected from a group consisting of 0.5 to 3% by weight of SQdium lauryl sulfate, 0.05 to 1% by weight of sodium sarcosine laurate, 0.5 to 5% by weight of alkyl polyglucoside and 0.

Abstract: The present invention relates to an oral care composition comprising nanoparticulate titanium dioxide, optionally together with a source of fluoride ions, for combating dental erosion and/or tooth wear. In addition such compositions may also have benefit in tooth whitening. When a source of fluoride ions is present such compositions are also of benefit in combating dental caries.

Abstract: A dental remineralizing system, including a functionalized calcium-containing complex having an organic surfactant component mechanochemically attached to a distressed calcium phosphate component and blended with the comestible material.

Abstract: This invention relates generally to compositions for whitening human teeth, and more particularly, to compositions that do not contain hydrocarbon humectants and which, when applied onto the surface of teeth act to whiten without damage to tooth surfaces. They do contain a hydrogel, defined as a gel that does not contain a hydrocarbon humectant. A hydrocarbon humectant is defined as a carbon, hydrogen and oxygen compound which is used to prevent the oral care composition from hardening upon exposure to air or a carbon, hydrogen and oxygen compound which is used as a carrier for ingredients of an oral care composition.

Abstract: The present invention provide formulations with antibacterial and biofilm removing actions comprising plant extracts, comprising at least one plant oil wherein the plant is selected from the group comprising the genus Protium, Guatteria, Cyperus in a suitable vehicle.

Abstract: An acidic mouthwash is described comprising xanthan gum and an alkali metal fluoride which enhances fluoride uptake into teeth and provides protection against acidic challenges.

Abstract: The present invention relates to an anti-caries composition that includes Silver Diamine Fluoride (SDF) and a carrier, and methods for using the composition. In particular, the composition includes SDF in an amount between about 1% and about 40% by weight; and a carrier (e.g., natural adhesive, a synthetic adhesive, a drying adhesive, an emulsion adhesive, silicone, copal, glass ionomer, cyanoacrylate, composite resin, latex, epoxy, silicone, polyurethane, denture adhesives, or variants thereof or any combination thereof. The methods of the present invention relate to arresting caries or reducing the number of active caries lesions. The steps include applying the anti-caries SDF composition to one or more tooth surfaces for about 1-5 minutes, and rinsing the composition from the tooth surface. Another method of the present invention relates to applying a SDF composition to the tooth surface, curing the composition, to thereby treat caries.

Abstract: The present invention relates to peroxide containing oral care compositions containing a flavor system that effectively masks the undesirable taste and sensations due to peroxide. The flavor system comprises menthol, at least one other secondary coolant and selected flavor chemicals that together provide a stable flavor profile and a high impact refreshing taste and sensation. The secondary coolant is selected from carboxamides, ketals, diols, menthyl esters and mixtures thereof.

Abstract: The present invention relates to oral care compositions providing improved substantivity to and for the tissues and hard surfaces of the oral cavity.

Abstract: The present invention relates to aqueous or aqueous-alcoholic compositions comprising at least one cationic polymer a) and at least one polymer b) with a molecular weight Mw of at most 200 000 g/mol which comprises N-vinylimidazole in copolymerized form, to methods for producing such compositions and to the use of such compositions in cosmetics.

Abstract: Use of osteopontin for reducing plaque bacterial growth on tooth enamel and dental formulations containing osteopontin.

Abstract: A method of making an oral care composition comprising the addition of a fused silica slurry.

Abstract: A method for preparing amorphous calcium phosphate (ACP) and oral care composition containing ACP prepared by the same are disclosed, wherein the method comprises the following steps: (a) cleaning and pulverizing the oyster shells; (b) sintering the oyster shells to obtain a calcium-containing powder; (c) dissolving the calcium-containing powder in water to obtain a calcium-containing solution; and (d) mixing the calcium-containing solution with a other phosphate-containing solution, to produce amorphous calcium phosphate. The method of the present invention not only can simplify the process and reduce the cost, but also can solve the problem of environment pollution resulting from wasted oyster shells. In addition, the ACP prepared in accordance with the method of the present invention further comprises some trace elements, such as strontium (Sr) and fluoride (F), which can improve dental health.

Abstract: An oral care composition comprising a fused silica abrasive and a stannous ion source.

Abstract: An oral care composition comprising fused silica and an oxidizing agent.

Abstract: Dental compositions containing adjuvants are provided that have the capability of undergoing an increase in viscosity in response to an increase in temperature. In a preferred embodiment, the compositions also have the ability to reverse their viscosity in response to a decrease in temperature.