Abstract: An antiseptic formulation capable of providing antimicrobial properties over an extended period of time is disclosed. The formulation includes chelated metal ions and a fixative polymer with the capacity to bond the chelated metal ions to the skin. This fixative polymer, polyquaternium-69 has the ability to bond chelated metal ions, and other types of antimicrobial agents, to the skin for periods of hours or days depending on the conditions in which it is used. An antiseptic liquid formulation can be integrated in a soap product and a spray product. An antiseptic gel formulation is further disclosed.

Abstract: The use of docosahexaenoic acid in the manufacture of a composition for administration to a pregnant woman for reducing the risk of development of overweight or obesity of the baby in infancy and/or early childhood.

Abstract: A molluscicidal composition, comprising: a molluscicide; a molluscicidal activity promoting additive comprising a calcium-containing salt of ethylene disuccinic acid or calcium ions and ethylenediamine disuccinic moieties, having at least 1 mole of calcium per mole of ethylenediamine disuccinic acid; and a carrier material edible to molluscs.

Abstract: The present invention relates to post-treatment compositions and methods useful for modifying the distribution of metal biocide(s) in biodegradable substrates such as wood, other cellulosic products, starch-based products, and the like that are vulnerable to decay due to insects, fungi, microbes, and the like. The compositions include complexing agents of moderate strength that are able to facilitate mobilization and redistribution of metal biocide(s) in substrates without undue leaching. The compositions can be used, for example, to redistribute the metal biocide(s) into depleted regions of a substrate by redistribution of metal biocide from other regions of the substrate. Post-treatment compositions that include additional metal biocide can also replenish these regions with the freshly supplied, additional biocide. Thus, the depleted regions can be restored by redistribution and/or replenishment mechanisms. Service life of substrates in the field benefits by these post-treatments as a consequence.

Abstract: The present invention relates to the use of hydrazone compounds and copper for controlling the growth of fungi.

Abstract: The present invention relates to the use of hydrazone compounds and copper for controlling the growth of fungi.

Abstract: Metal particulates capable of generating low levels of corrosion current beneficial for pharmaceutical, cosmetic and other medical uses are provided.

Abstract: The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, vitamin D, vitamin C, vitamin E, folic acid, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, calcium, iron, magnesium, zinc, and/or copper, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, vitamin D, vitamin C, vitamin E, folic acid, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, calcium, iron, magnesium, zinc, and/or copper, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.

Abstract: In one aspect, the invention relates to a method of making an emulsion composition. The method includes forming a water-in-oil emulsion and adding a galvanic particulate to the water-in-oil emulsion. In another aspect, a water-in oil emulsion is provided. The water-in-oil emulsion includes a water phase emulsified in a continuous oil phase; and a galvanic particulate. The oil-in water emulsion has a yield stress of at least about 20 Pascals (Pa).

Abstract: The invention relates to a biological preparation comprising orthosilicic and silicic acid, a primary (“constant/first”) osmolyte choline and a weak alkalinizing agent without free hydroxyl groups and to a method for preparing the preparation, comprising: i) hydrolyzing a silicon comprising choline solution thereby forming a choline stabilized orthosilicic acid and oligomers solution; ii) alkalizing the choline orthosilicic acid and oligomers solution by adding a weak alkalizing agent without hydroxyl groups; and iii) optionally adding a divalent trace element and/or secondary osmolyte, to biological preparation obtainable and its uses.

Abstract: The present invention relates to the use of hydrazone compounds and copper for controlling the growth of fungi.

Abstract: The present invention relates to the use of mixtures containing hydrazone compounds and copper for controlling the growth of fungi.

Abstract: The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloalkyl; R2 is an optionally substituted aryl or heteroaryl; R3 is halogen; R4 is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, hydroxyl, C1-C4alkoxy, OR6, C1-C4haloalkoxy or cyano; R5 is halogen; R6 is hydrogen, C3-C7 cycloalkyl, C3-C10 alkylcycloalkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C3-C7 cycloalkenyl, C2-C6 alkynyl, C2-C6 haloalkynyl or C2-C6 alkyloxyalkyl; X is N or C(R); and R is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; or an agrochemically usable salt form thereof; provided that when X is C(R), R2 cannot be an optionally substituted aryl.

Abstract: The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.

Abstract: Provided herein is a prenatal and postpartum multivitamin and mineral supplement package provided in the form of a plurality of solid oral dosage units individually contained in blister packs wherein a portion of the dosage forms are iron-containing while at least half of the dosage units are essentially iron-free and wherein the total amount of iron in the package as sold to purchasers is less than about 1300 mg of elemental iron.

Abstract: A micronutrient supplement the supplement being characterized by having at least two types of distinct dosage units wherein said distinct dosage units which physically separate nutritional, vitamin or mineral supplements which are known or proven to be negatively interacting when co-mingled or co-administered, the distinct dosage units being designed to be taken at a predetermined time interval.

Abstract: Methods, compositions, and strategies for the treatment of malignant neoplasms are presented herein. The treatment modalities are directed towards exploiting characteristics of cancer cells as well as correcting defective biochemical pathways and systems in the body.

Abstract: A method of preventing or treating conditions of peri-menopausal, menopausal, or post-menopausal skin comprising applying to the skin tissue, a safe and effective amount of a composition comprising between 1.0% to 3% by weight of S-palmitoyl glutathione and a dermatologically acceptable carrier.

Abstract: A treatment system and method for osteopenia and osteoporosis using non-synthetic bio-available hormones, vitamins, minerals, and agents may be customized by varying the dosage and formulation of the components to maximize therapeutic effect, bioavailability, and patient comfort and compliance with their treatment method, the treatment system including a storage unit including a determined number of applications of hormones, minerals, and vitamins of appropriate dosages for treating the patient with osteopenia and osteoporosis.

Abstract: The present invention provides compositions comprising vitamins, minerals, nutrients, sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.

Abstract: The present invention relates to hydrogels endowed with antibacterial properties, to be used for injection in damaged bones or in the production of antibacterial coatings of prostheses for implant in the human or animal body, obtained by loading with antibacterial agents hydrogels formed by derivatives of hyaluronic acid; the invention also relates to a kit of parts for producing the antibacterial hydrogels.

Abstract: The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a metal salt (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. In particular the combinations according to the invention are useful to obtain plants with greener leaf color.

Abstract: Structures treated with a microbiological interception enhancing agent comprising of a water-soluble cationic material having a counter ion associated therewith at specific sites on the cationic material, in combination with a biologically active metal salt, wherein the counter ion associated with the cationic material preferentially precipitates with at least a portion of the cation of the biologically active metal salt such that precipitation of the biologically active metal cation and the counter ion associated with the cationic material occurs in proximity to the cationic material are disclosed herein. The microbiological interception enhancing agent may be incorporated into articles of commerce by treating the starting materials of the structure or by applying the microbiological interception enhancing agent on to at least one surface of the article.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: The invention provides a method for imparting antiviral properties to a hydrophilic polymeric material comprising preparing a hydrophilic polymeric slurry, dispersing an ionic copper powder mixture containing cuprous oxide and cupric oxide in said slurry and then extruding or molding said slurry to form a hydrophilic polymeric material, wherein water-insoluble particles that release both Cu++ and Cu+ are directly and completely encapsulated within said hydrophilic polymeric material.

Abstract: The present invention relates to a wood preservative containing as an active ingredient 3?-isopropyl-2-trifluoromethyl benzoic acid anilide represented by the formula below and a wood treatment method using the same. The present invention can provide a wood preservative having excellent preservation effect on various wood-destroying fungi with a very small chemical dosage and a wood treatment method, which are economical and have a small environmental load.

Abstract: Provided is a composition for the preservation of wood and other cellulosic materials. The composition comprises a dispersion of micronized inorganic compounds and/or organic biocides in an organic carrier. Also provided is a method for making the composition.

Abstract: The invention relates to a versatile disinfectant containing as main components, a metal ion having an antimicrobial action, L-cysteine and L-ascorbic acid, characterized in that it contains a surfactant excluding a nonionic surfactant in addition to these main components. The versatile disinfectant may further contain one or more compounds selected from the group consisting of sorbic acid, sorbates, benzoic acid, benzoates and p-hydroxybenzoate esters. The pH of the versatile disinfectant is preferably adjusted to 2.5 to 4.0. The disinfectant can disinfect an object to be treated for an environment, an apparatus, a human body, an animal body, a plant body, an organic matter or the like by bringing the disinfectant into contact with such an object to be treated.

Abstract: Topical skin care compositions containing a combination of ascorbic acid or a derivative thereof, brown algae extract, and a blend of botanical extracts comprising cucumber extract, watercress extract, birch leaf extract, red clover extract, and St. John's wort extract, and, optionally, ginseng extract, as well as methods of using the same, are disclosed.

Abstract: The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of an aptamer and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions.

Abstract: The invention relates to a drug or a dermatological composition containing an avocado peptide extract for treating and/or preventing pruritus, in particular gravidic pruritus, pruritus sine materia, pruritus in newborns, and pruritus originating from a drug.

Abstract: A composition of matter and the method of making that provide a low pH acidic composition that is useful for destroying microorganisms that are undesirable and useful for destroying or reducing melanoma on human skin. The composition and method include a strong, low pH acid combined with distilled water and urea or an ammonium compound, such as ammonium sulfate or other metallic sulfates, including but not limited to, sodium sulfate, magnesium sulfate, zinc sulfate, manganese sulfate, and copper sulfate, under at least 15 psi pressure in pressurized container, all of which is heated to approximately 800° F. or more for at least 3 hours. The final cooled mixture is stabilized with 10 to 15 percent of the original mixture. The resultant composition is useful for preserving food, such as fresh fish, and for skin treatment of melanoma and as bactericides, fungicides, or viricides.

Abstract: Disclosed is a high efficiency disinfectant cleaner that is stable and shows antibacterial activity. This disinfectant cleaner basically comprises nanoparticles of silver, copper or gold; at least one surfactant which includes a quaternary ammonium surfactant; a solvent; a gelling agent; and water. Thanks to the use of the gelling agent, the disinfection cleaner remains stable and homogenous. The nanoparticles are kept in suspension, since the gelling agent does not allow deposition of them. Since deposition at the bottom of the solution is prevented, agglomeration to ineffective bigger size particles is also inhibited and the disinfectant stability and efficacy are conserved. The improved stability of the composition and the synergic effect of specific ingredients improve the antibacterial efficiency by decreasing tremendously the required killing contact time.

Abstract: Novel lip compositions are disclosed. The lip compositions comprise galvanic particulates and provide the following benefits: enhanced lip color, reduced fine lines and wrinkles, increased fullness, improved moisturization, smoothness, texture, and improved definition and lip contour.

Abstract: The present invention provides compositions and methods for treatment of abnormal conditions in a subject, wherein the abnormal condition affects the musculoskeletal joints of the subject.

Abstract: A composition includes ascorbate, zinc gluconate, and tropocollagen factors including L-proline, glycine and L-lysine. The composition contains the ascorbate, tropocollagen factors and zinc gluconate in concentrations effective to accelerate the production of collagen proteins within at least one collagen-containing tissue of an animal when administered to the animal. The at least one collagen-containing tissue includes at least one of cartilage tissue, tendon tissue, ligament tissue, vitreous humor tissue, connective tissue, hair tissue, bone tissue, and corneal tissue.

Abstract: A nutritional supplement for use in physiologically stressful conditions is disclosed. The nutritional supplement may include one or more of vitamin A, vitamin E, vitamin D3, vitamin C, vitamin B1, riboflavin, niacin, folic acid, vitamin B6, biotin, pantothenic acid, vitamin B12, magnesium, zinc, selenium, chromium, copper, iron, alpha lipoic acid, lutein and lycopene.

Abstract: A nutritional supplement for use in physiologically stressful conditions is disclosed. The nutritional supplement may include one or more of vitamin A, vitamin E, vitamin D3, vitamin C, vitamin B1, riboflavin, niacin, folic acid, vitamin B6, biotin, pantothenic acid, vitamin B12, magnesium, zinc, selenium, chromium, copper, iron, alpha lipoic acid, lutein and lycopene.

Abstract: The invention relates to the use of PDE5 inhibitors for treating and/or preventing hypopigmentary disorders.

Abstract: The invention relates to a process for production of a composite material having antimicrobial activity, having the following steps: provision of a metal powder produced from a metal having antimicrobial activity, wherein the metal powder is formed from discrete agglomerates having a porosity of 30 to 98%, wherein the agglomerates have a spongy structure formed by solid material bridges; melting a thermoplastic and setting a predetermined viscosity; mixing the metal powder with the molten thermoplastic in a predetermined quantitative ratio; and cooling the mixture, wherein the metal powder is firmly bound to a matrix formed by the plastic.

Abstract: A nutritional supplement comprising the following approximate amounts: Vitamin/mineral Range Vitamin C 60-150 mg Vitamin D (as cholecalciferol) 400-10,000 IU Thiamin (Vitamin B1) 1-50 mg Riboflavin (Vitamin B2) 1-10 mg Vitamin B6 2-50 mg Folic Acid 0.

Abstract: A cosmetic composition with superior moisturizing benefits comprising from approximately 0.3% to approximately 0.9% by weight of bio-chelated mineral blend comprising silicon, magnesium, copper, iron, zinc, and calcium, and at least approximately 85.0% by weight of a humectant blend. Preferably, the bio-chelated mineral blend comprise Saccharomyces zinc ferment, Saccharomyces copper ferment, Saccharomyces magnesium ferment, Saccharomyces iron ferment, Saccharomyces silicon ferment, and Saccharomyces calcium ferment in equal amounts, more preferably from approximately 0.05% to approximately 0.15% by weight of each component. The humectant blend preferably comprises glycerin, beet root extract, and Aloe barbadensis leaf polysaccharides.

Abstract: The present invention provides nanocomposite systems made of metallic nanoparticles stabilized with branched cationic polysaccharides, in particular alditolic or aldonic mono- and oligo-saccharidic derivatives of chitosan, and their preparation obtainable with aqueous solutions of these polysaccharides in the presence or absence of reducing agents. The peculiar chemical and physical-chemical features of these polysaccharides allow to form metallic nanoparticles homogeneously dispersed in the polysaccharidic matrix and an effective stabilization thereof. The properties associated with the nanometric dimensions and the presence of biological signals on polymeric chains may be exploited in applications with antimicrobial activities and of molecular biosensors.

Abstract: In the present invention nanocomposite materials in form of three-dimensional structure formed by a polymeric matrix consisting of a polysaccharidic composition of neutral or anionic polysaccharides and a branched cationic polysaccharides, in which metallic nanoparticles are uniformly dispersed and stabilized, are described. Using appropriate techniques of gelification or by means of an appropriate dehydration, the nanocomposite materials are three-dimensional matrices having different shapes in hydrated form as hydrogels, or in non-hydrated form. These nanocomposite materials have a broad-spectrum of strong bactericidal activity, but do not show any cytotoxicity.

Abstract: The present invention provides improved dietary supplements and methods for alleviating the symptoms of dry eye. The dietary supplements of the invention contain omega-3 fatty acids and flavonoids.

Abstract: A method of treating neoplastic disease in a human or animal patient is provided comprising administering to the patient an anti-neoplastic effective amount of a composition comprising as the sole pharmaceutically active components (a) copper gluconate or copper orotate; (b) sodium salicylate; (c) vitamin C; (d) manganese gluconate or manganese orotate; and optionally one or more of (e) iron gluconate or iron orotate; (f) sublimed sulphur; and (g) zinc gluconate or zinc orotate.

Abstract: A solution for wood preservation is suitable for preservation of wood against wood pests (fungi, insects, termites) that increases resistance of wood against biotic and abiotic factors of decay. The solution for wood preservation comprises an aqueous solution of amine, copper salt, boron salt, quaternary ammonium compound, and carboxylic acid. Preferable embodiment is a solution for wood preservation, consisting of ethanolamine, copper (II) sulphate, disodium octaborate tetrahydrate, alkylbenzyldimethyl ammonium chloride, and octanoic acid dissolved in water. This composition may result in improved copper fixation (decreased leaching of active ingredients from wood during weathering) and improved resistance against the most important wood destroying organisms like wood decay fungi, insects and termites.

Abstract: A trace element solution includes at least the metals: zinc, manganese, selenium, and copper, and comprises a concentration of the metal(s) of at least 90 mg/ml. The solution may comprise the following concentrations: at least 60 mg/ml zinc; at least 10 mg/ml manganese; at least 5 mg/ml selenium; and at least 15 mg/ml copper. The solution may furthermore comprise chromium and iodine.

Abstract: A liquid solution for topical application to the skin of an animal consists of solutes and a solvent, where the solutes include ascorbate, tropocollagen factors, copper, and zinc gluconate. The tropocollagen factors include L-proline, glycine and L-lysine.

Abstract: The present invention provides a composition for topical treatment of skin and mucosal membrane lesions comprising a synergistic combination of copper compound and hypericum perforatum extract.