Chromium Patents (Class 424/655)
  • Publication number: 20150139938
    Abstract: The present invention provides methods of promoting arteriogenesis in a subject. Embodiments include methods comprising: administering an effective dose of tocotrienol to the subject; causing an increase in Tissue Inhibitor of Metalloproteinase Metallopeptidase Inhibitor 1 (TIMP1) in vessels of cerebrovascular collateral circulation in the subject; attenuating the activity of Matrix Metalloproteinase-2 (MMP2); thereby promoting arteriogenesis.
    Type: Application
    Filed: June 7, 2013
    Publication date: May 21, 2015
    Applicant: Ohio State Innovation Foundation
    Inventors: Chandan Sen, Cameron Rink, Sashwati Roy, Greg Christoforidis
  • Patent number: 9028879
    Abstract: The embodiments disclosed herein relate to compositions for enhancing brain glucose transporters, such as GLUT1 and GLUT3, and methods of treating and/or preventing diseases or disorders associated with the regulation GLUT1 and GLUT3. Also provided are compositions that include chromium and an agent that targets the brain or the central nervous system. Further provided are improved methods of delivering therapeutic agents that target the brain and/or central nervous system.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: May 12, 2015
    Assignee: JDS Therapeutics, LLC
    Inventor: James R. Komorowski
  • Publication number: 20150086648
    Abstract: Methods of treating, reducing, and/or preventing heat stress are provided. For example, provided is a method of treating or preventing heat stress in a subject comprising selecting a subject in need of heat stress treatment or prevention and administering an effective amount of one or more of astaxanthin and milk casein hydrolysate, or a derivative thereof to the subject. Also provided are methods of reducing the effects of a fever in a subject comprising administering an effective amount of one or more of astaxanthin, chromium and milk casein hydrolysate, or a derivative thereof, to the subject. Also provided are pharmaceutical compositions, comprising astaxanthin and one or more of chromium or milk casein hydrolysate.
    Type: Application
    Filed: October 7, 2014
    Publication date: March 26, 2015
    Inventor: Harry George Preuss
  • Publication number: 20150079199
    Abstract: This document provides dietary supplement compositions as well as methods for using dietary supplement compositions to control glucose levels. For example, a dietary supplement composition including chromium (e.g., Chromium Oligofructose Complex), a sweet potato extract, and one or more of a mulberry extract, a green tea extract, a cinnamon extract, or a ginseng extract (e.g., Korean Red Ginseng extract) are provided.
    Type: Application
    Filed: May 16, 2012
    Publication date: March 19, 2015
    Applicant: MELALEUCA, INC.
    Inventor: Jeremy Ivie
  • Publication number: 20150023941
    Abstract: The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.
    Type: Application
    Filed: October 6, 2014
    Publication date: January 22, 2015
    Inventors: David Bagley, Scott Momii, Scott Nagasawa, Herbert T. Nagasawa
  • Publication number: 20150017260
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Application
    Filed: July 28, 2014
    Publication date: January 15, 2015
    Inventors: Jacqueline M. Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Patent number: 8933022
    Abstract: A composition comprising chromium and insulin and/or a chromium-insulin complex, its method of preparation, and its use in the prevention and treatment of hypoglycemia and hypoglycemia-related conditions. This composition can be administered in numerous ways, including parenterally, intranasally, and orally. The composition stabilizes serum glucose levels and has a synergistic effect compared to chromium and insulin administered separately.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: January 13, 2015
    Assignee: JDS Therapeutics, LLC
    Inventor: James R. Komorowski
  • Patent number: 8911724
    Abstract: Provided are methods and compositions for increasing CD4+ cell count in mammals, preferably by at least 25%, while undergoing treatment for various conditions whose treatment can have detrimental effects on immune system function. Such conditions include, but are not limited to, HIV infection, cancer, and hepatitis. The compositions include alpha lipoic acid; acetyl L-carnitine; N-acetyl-cysteine; and optionally: zinc, selenium, vitamin C, bioflavinoid complex, vitamin E, co-enzyme Q10, glutathione, beta-carotene, vitamin A, vitamin B1, vitamin B2, vitamin B6, niacinamide, calcium pantothenate, folic acid, vitamin B12, copper, manganese, chromium, and molybdenum.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: December 16, 2014
    Assignee: K-PAX Pharmaceuticals, Inc.
    Inventor: Jon D. Kaiser
  • Patent number: 8877819
    Abstract: Methods of treating, reducing, and/or preventing heat stress are provided. For example, provided is a method of treating or preventing heat stress in a subject comprising selecting a subject in need of heat stress treatment or prevention and administering an effective amount of one or more of astaxanthin and milk casein hydrolysate, or a derivative thereof to the subject. Also provided are methods of reducing the effects of a fever in a subject comprising administering an effective amount of one or more of astaxanthin, chromium and milk casein hydrolysate, or a derivative thereof, to the subject. Also provided are pharmaceutical compositions, comprising astaxanthin and one or more of chromium or milk casein hydrolysate.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: November 4, 2014
    Assignee: Georgetown University
    Inventor: Harry George Preuss
  • Publication number: 20140322357
    Abstract: The invention is directed to a composition comprising chromium and L-Arabinose. The invention is also directed to a method for decreasing the metabolization of sucrose in a host in need thereof by administering a composition comprising chromium and L-Arabinose to a host and a method for inhibiting the glycemic response to a meal containing sucrose in a host in need thereof by administering a composition comprising chromium and L-Arabinose to a host.
    Type: Application
    Filed: July 7, 2014
    Publication date: October 30, 2014
    Inventor: Mitch Skop
  • Publication number: 20140286923
    Abstract: According to one embodiment, a nutritional supplement for suppressing an appetite while maintaining muscle mass of a subject during weight loss is provided. The nutritional supplement includes beta-hydroxy beta-methylbutyric acid (HMB), chromium, and Caralluma fimbriata.
    Type: Application
    Filed: November 5, 2012
    Publication date: September 25, 2014
    Applicant: University of Florida Reseach Foundation, Inc.
    Inventor: Maria Grant
  • Publication number: 20140271924
    Abstract: Compositions and methods for modulating blood sugar are provided. The composition comprises gymnema, green coffee, grape seed, hibiscus, cinnamon, holy basil, Russian tarragon, ginger, turmeric, and chromium.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: New Chapter, Inc.
    Inventors: Taryn Louise FORRELLI, Paul SCHULICK
  • Publication number: 20140271558
    Abstract: Beta glucan and fulvic acid can be combined in a dietary supplement as a partial substitute or complete replacement for blue green algae and/or brown seaweed and its derivatives. Beta glucans are widely available as derivatives of Brewer's yeast and fulvic acid is widely available as well. These supplements are not subject to the vagaries of weather-influence growing seasons as is the case with blue green algae and brown seaweed. When combined, beta glucan and fulvic acid can provide a less costly dietary supplement than blue green algae and brown seaweed and its derivatives such as fucoidan.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Cappellos, Inc.
    Inventor: John V. Cappello
  • Publication number: 20140242188
    Abstract: An aqueous composition with a higher-than-neutral pH includes a significant amount of one or more surfactants and large amounts of osmotically active solutes. This composition, as well as an acidic counterpart and solid materials, can be used in a variety of applications such as wound care, oral care, medical equipment reprocessing, healthcare acquired infection and implant treatment.
    Type: Application
    Filed: October 8, 2012
    Publication date: August 28, 2014
    Applicant: Next Science, LLC
    Inventor: Matthew Franco Myntti
  • Publication number: 20140220152
    Abstract: Disclosed herein is a non-human animal model of protein aggregation cardiomyopathy. Also disclosed are compositions and methods of treating or preventing a condition in a subject caused or exacerbated by reductive stress. Also disclosed are compositions and methods of predicting, detecting, or monitoring reductive stress in a subject.
    Type: Application
    Filed: September 12, 2013
    Publication date: August 7, 2014
    Applicant: University of Utah Research Foundation
    Inventors: Ivor J. Benjamin, Namakal S. Rajasekaran, Thomas P. Kennedy
  • Publication number: 20140212508
    Abstract: A Copper/Zinc superoxide dismutase (Cu/Zn SOD) composition comprising a therapeutically effective amount of ionic mineral(s) in a ligand complex and a pharmaceutically acceptable carrier for the neutralization of superoxide produced trauma and/or stress-related conditions including, but not limited to, conditions such as myotrophic lateral sclerosis (ALS). The composition may also include other supporting adjutants such as bioavailable magnesium, manganese, selenium and other minerals that can support the nervous system and other vitamins and glutathione and other nutrients. Botanical extracts, urea, other supplements helpful for protection and re-enforcement of the immune system are discussed.
    Type: Application
    Filed: April 3, 2014
    Publication date: July 31, 2014
    Inventor: John Wayne Kennedy
  • Patent number: 8771752
    Abstract: A composition for preventing and treating fatty liver is disclosed. The composition includes a lactoferrin and a trivalent chromium compound. The trivalent chromium compound of the present invention is selected from the group consisting of chromium (III) chloride hexahydrate, chromium (III) chloride, chromium (III) acetate, chromium (III) sulfate, chromium picolinate, chromium nicotinate, chromium GTF, chromium yeast extract, other inorganic salts of trivalent chromium, other organic salts of trivalent chromium, and combinations thereof. The composition of the present invention can provide a beneficial effect in preventing and treating fatty liver by effectively reducing multiple risk factors of fatty liver disease.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: July 8, 2014
    Assignee: National Chung Hsing University
    Inventors: Frank Chiahung Mao, Wen-Ying Chen
  • Patent number: 8771751
    Abstract: The invention relates to a medical implant made of a metallic material. After fulfilling its temporary support function, the implant is degraded by corrosion at a predetermined rate. Negative long-term effects are thus avoided.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: July 8, 2014
    Assignee: Biotronik AG
    Inventors: Bernd Heublein, Gerd Hausdorf
  • Publication number: 20140170128
    Abstract: Disclosed herein are compositions, products, and methods that treat glycated hemoglobin- and blood glucose-affected conditions by improving insulin function for the control and maintenance of blood glucose levels, alleviating oxidative stress, minimizing the risk of developing disease complications, facilitating the loss of weight and maintenance of healthy weight, and at the same time fulfill cravings for pleasant-tasting items of consumption and in turn increase the likelihood of patient compliance with the relevant therapy regimen. The disclosed compositions, products, and methods implement proteins and peptides that provide insulinotropic metabolic products in a sustained manner, in combination with ingredients that, for example, provide sustained release of carbohydrates, steady energy, sustained antioxidant effect relieve oxidative stress, and promote satiety, in order to reduce A1c and blood glucose levels and avert weight gain among subjects in need.
    Type: Application
    Filed: December 17, 2012
    Publication date: June 19, 2014
    Inventor: VIJAI K. PASUPULETI
  • Patent number: 8703211
    Abstract: The invention relates to the treatment and prophylaxis of cancer. In particular, the invention relates to a pharmaceutical agent comprising strontium, amino acid(s) and mineral element(s), and its use in the preparation of an agent useful for the treatment and prophylaxis of cancer. The invention also relates to a method for treatment and prophylaxis of cancer.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: April 22, 2014
    Assignee: Oy Neurofood AB
    Inventor: Thomas Tallberg
  • Publication number: 20140106006
    Abstract: The invention relates to a synergistic combination of trivalent chromium, biotin and American ginseng, which is effective for the treatment of type 2 diabetes mellitus. It also relates to dietetic compositions which include such combination that are appropriate for treatment of type 2 diabetes mellitus in obese patients. It also relates to the use of said combination for the preparation of a medicament for the treatment of that type of diabetes.
    Type: Application
    Filed: June 5, 2012
    Publication date: April 17, 2014
    Applicant: PRI, S.A.
    Inventor: Farouk Radwan
  • Publication number: 20140072647
    Abstract: The present invention relates to a method for maintaining normoglycemia in a mammal in need thereof, preferably a critically ill patient suffering from acute stress, and to a method for preventing or limiting renal ischemia-reperfusion (I/R) in a mammal, preferably in a critically ill patient suffering from acute stress.
    Type: Application
    Filed: March 6, 2012
    Publication date: March 13, 2014
    Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer
  • Publication number: 20140044685
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, ?-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 13, 2014
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • Publication number: 20140030241
    Abstract: Nutritional compositions having dietary nucleotides, ?-3 fatty acids and citrulline are provided. The nutritional compositions may be formulated to improve T cell function, increase arginine availability in vivo, regulate myeloid-derived suppressor cells (“MDSC”), and decrease the risk and/or severity of infection after surgery or trauma. Methods of making, using and administering such nutritional compositions to individuals in need of same are also provided. Methods for modulating the affects of MDSC's are also provided.
    Type: Application
    Filed: March 15, 2012
    Publication date: January 30, 2014
    Applicant: NESTEC S.A.
    Inventor: Norman Alan Greenberg
  • Publication number: 20130330422
    Abstract: Disclosed are methods and compositions related to increasing insulin sensitivity and treating diabetes.
    Type: Application
    Filed: June 7, 2013
    Publication date: December 12, 2013
    Applicant: The Board of Trustees of the University of Alabama
    Inventor: John B. Vincent
  • Publication number: 20130295199
    Abstract: This invention relates to a composition comprising oligoproanthocyanidins (OPC) and omega-3 fatty acids, for use in preventing or stabilizing the development and/or the progression of a diabetes-related eye condition in a subject; this invention includes a functional food, a nutraceutical composition or a food or dietary supplement comprising said composition; this invention also relates to a pharmaceutical composition or a veterinarian product comprising oligoproanthocyanidins (OPC) and omega-3 fatty acids.
    Type: Application
    Filed: January 13, 2012
    Publication date: November 7, 2013
    Applicant: VISIOTACT PHARMA
    Inventors: Reda Hadj-Slimane, Yves Lepelletier, Tewfik Hadj-Slimane
  • Publication number: 20130209580
    Abstract: A method of treating Alzheimer's Disease of users comprising daily use of a lotion, the components of which are disclosed, a daily supplementation with powdered whey protein and Vitamin D, and a mild exercise component.
    Type: Application
    Filed: February 14, 2012
    Publication date: August 15, 2013
    Inventor: Kenneth O. Russell
  • Publication number: 20130183277
    Abstract: Provided are compositions and methods for increasing patient CD4+ cell count while undergoing treatment for immune-mediated disease, cancer, heart disease, neurodegenerative disease, or infectious disease by administering to the patient a nutrient composition including, inter alia, alpha lipoic acid, acetyl L-carnitine, and N-acetyl-cysteine.
    Type: Application
    Filed: December 19, 2012
    Publication date: July 18, 2013
    Inventor: Jon D. Kaiser
  • Publication number: 20130103120
    Abstract: There is disclosed therapeutic devices or sanitary articles intended for the treatment of diseases and/or disorders of the tonic/postural system, containing a composition which emits and/or reflects light energy in the far infrared spectrum and which includes a ceramic material. Also disclosed is the use of a composition which emits and/or reflects light energy in the far infrared spectrum and which includes a ceramic material in the preparation of therapeutic devices or sanitary articles intended for the treatment of diseases and/or disorders of the tonic/postural system, in particular, orthodontic devices, glasses and plasters.
    Type: Application
    Filed: June 29, 2011
    Publication date: April 25, 2013
    Inventor: Sergio Ettore Salteri
  • Publication number: 20130101681
    Abstract: Provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising chromium and histidine, chromium histidinate complexes, or combinations thereof, to the individual.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 25, 2013
    Inventors: Vijaya Juturu, James Komorowski
  • Publication number: 20130071491
    Abstract: An extrusion process for producing a uniform and highly expanded food product is disclosed with nutritional yeast and chromium. The uniform expansion ratio possessed by the extruded product provides a consistent texture and has application in a wide variety of food consumables, ranging from snacks to breakfast cereals.
    Type: Application
    Filed: December 9, 2011
    Publication date: March 21, 2013
    Inventors: Jose De J. Berrios, Peter Justen, Wei Hua A. Cheong
  • Publication number: 20130064884
    Abstract: A method for prophylactic treatment of ketosis in a calving cow, the method including orally administering to the cow within a time period of about 12 hours after calving an effective dose of from 20 to 30 g of rumen protected methionine. If the cow falls into a risk category, the cow is administered the dose of rumen protected methionine once a day on the second, third, fourth, and fifth days after calving. Also, a composition including a gelatin capsule and rumen-protected methionine contained within the gelatin capsule that may be administered to a calving cow for the prophylactic treatment of ketosis. The composition may further contain within the gelatin capsule one or more other compounds known to have efficacy on fat or glucose metabolism, such as glucose, propylene glycol, niacin, choline, chromium, calcium propionate, and glucocorticoids.
    Type: Application
    Filed: September 8, 2011
    Publication date: March 14, 2013
    Applicant: RP FEED COMPONENTS, LLC
    Inventors: James M. ROHRER, Patrick D. FRENCH, Keith F. MORITZ
  • Publication number: 20130052278
    Abstract: The present disclosure provides a rapidly disintegrating orally administrable powder. The powder may include an active ingredient such as a dietary supplement. Methods of using the same are also provided herein.
    Type: Application
    Filed: March 10, 2011
    Publication date: February 28, 2013
    Applicant: RICH VITAMINS LLC
    Inventors: Hallie N. Rich, Michelle G. Cannon
  • Publication number: 20130052275
    Abstract: This invention is a topical treatment for the skin, used for skin enhancement, firming, smoothing, refining and to reduce the appearance of cellulite; that has a self-warming or thermogenic effect comprised of a base combination of warming herbs (Ayurvedic), being any herbs that create a warming effect, combined with dietary minerals that can be blended together in any ratio.
    Type: Application
    Filed: August 22, 2012
    Publication date: February 28, 2013
    Inventor: Michelle Ward
  • Publication number: 20130045183
    Abstract: The present disclosure relates to non-acidic extracts or fractions selected from a Boswellia low polar gum resin extract fraction (BLPRE), a Boswellia volatile oil fraction (BVOIL), and a Boswellia oil fraction (BOIL) and their compositions. BLPRE, BOIL, and BVOIL are each derived from the gum resin of a Boswellia species. These compositions are useful for improving mental condition, enhancing brain functions such as cognition, memory, learning, communication and brain health, for treating impaired memory, and for preventing, control or treating memory and cognition related disorders/diseases. Additionally, BOIL, BVOIL, and mixtures of BOIL and BVOIL are useful for enhancing the bioavailability of a biological agent.
    Type: Application
    Filed: September 14, 2012
    Publication date: February 21, 2013
    Applicant: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Kiran BHUPATHIRAJU, Venkata Krishna Raju ALLURI
  • Patent number: 8377482
    Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: February 19, 2013
    Assignee: Warburton Technology Limited
    Inventors: Robert N. Laurie, William A. Smith
  • Patent number: 8349376
    Abstract: A novel dietary supplement is featured which can benefit individuals suffering from various conditions such as nutritional deficiencies, vitamin deficiencies, aging, dementia/Alzheimer's disease, high blood pressure, high cholesterol, coronary artery disease, stroke and mental cognition.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: January 8, 2013
    Inventor: Mark S. Bezzek
  • Patent number: 8309080
    Abstract: Metallo-proteins including but not limited to lactoferrin (LF), transferrin (TF) and ovotransferrin (OTF) (all members of transferrin family), ceruloplasmin (CP) and metallo-thionein (MT) were found to stabilize and enhance the bio-functional activity of tocotrienol (T3), T3 mixtures or derivates. The synergism between MP and T3 also promote the intestinal transfer and the ultimate bio-availability of T3 and T3-derivatives for physiological functions. Such functional synergism includes hypocholesterolemic, anti-thrombotic, antioxidant, anti-athermogenic, anti-inflammatory and immuno-regulatory activities of T3 agents. These T3 compositions are useful as pharmaceuticals, in cosmetics, in foods and as nutritional supplements.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: November 13, 2012
    Assignee: Naidu LP
    Inventors: A. Satyanarayan Naidu, A. G. Sreus Naidu, A. G. Tezus Naidu
  • Publication number: 20120251450
    Abstract: Of the many compositions and methods provided herein, one composition includes a nanoparticle having a first oxide of a first metal and a dopant that includes an ion or an atom of a second metal. A method includes a method comprising providing a plurality of nanoparticles comprising a first oxide of a first metal and a dopant that comprises an ion or an atom of a second metal; providing a diseased cell and a healthy cell; contacting the diseased cell and the healthy cell with the nanoparticle; and allowing the nanoparticle to preferentially associate with the diseased cell.
    Type: Application
    Filed: April 4, 2011
    Publication date: October 4, 2012
    Inventors: Alex Punnoose, Denise Wingett
  • Patent number: 8263147
    Abstract: Disclosed is a method of reducing the risk or severity of retinopathy of prematurity in preterm infants. The method comprises (a) measuring skin carotenoid levels in preterm infants, preferably by Raman Spectroscopy, and then (b) administering supplemental carotenoids to those infants in need thereof, wherein the supplemental carotenoids comprise lutein, lycopene, beta-carotene, and zeaxanthin. The supplemental carotenoids may be provided by an infant formula comprising, on a ready-to-feed basis, from about 100 to about 2000 mcg/liter of total carotenoids, wherein the total carotenoids include at least about 50 mcg/liter of lutein. The formulas may further comprise docosahexaenoic acid.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: September 11, 2012
    Assignee: Abbott Laboratories
    Inventors: Bridget Barrett-Reis, Pamela T. Price, Amy Mackey
  • Publication number: 20120225134
    Abstract: A composition comprising chromium and insulin and/or a chromium-insulin complex, its method of preparation, and its use in the prevention and treatment of hypoglycemia and hypoglycemia-related conditions. This composition can be administered in numerous ways, including parenterally, intranasally, and orally. The composition stabilizes serum glucose levels and has a synergistic effect compared to chromium and insulin administered separately.
    Type: Application
    Filed: March 1, 2012
    Publication date: September 6, 2012
    Applicant: N21 ACQUISITION HOLDING, LLC
    Inventor: James R. Komorowski
  • Publication number: 20120207854
    Abstract: Aqueous solution, cream, hydrogel or spray composition containing compound Sn-On-Xn; where S(n=5-8), O (n=3-7) and X?Fe, Cr or Ni, and most effectively, S7-O4-Fe4 as active ingredient for cutaneous, intradermal and subcutaneous treatment of dermo-epithelial lesions, comprising but not limited to, certain types of skin cancer (basal cell, keratocanthoma and spinocellular carcinomas), conjunctivitis, folliculitis, acne, gingivitis, stomatitis, fungal, dermatomycosis, parasitosis, condylomatosis, balanitis, vaginitis, vaginosis, bacteriosis and endometriosis; by reducing the number of infecting microorganism, not limited to Candida sp., Actinobacillus actinomycetemcomitans, Pseudomonas sp., Porphyromonas gingivalis., Escherichia, sp., Staphyloccocus sp. Streptococcus sp., Herpes simplex I, Herpes simplex II, Coxackievirus A and B, Echovirus, Varicella Zoster (HHV-3), Human Papilloma Virus Gardnerella Vaginalis, Trichomonas vaginalis, Corynebacterium sp., present on the body skin and mucosas.
    Type: Application
    Filed: February 11, 2011
    Publication date: August 16, 2012
    Inventors: Ricardo Carrizo-Manzanero, Rodolfo Salas-Auvert, Humberto Herrera-Merchan
  • Publication number: 20120189709
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Publication number: 20120183630
    Abstract: The present invention realtes to compositions and methods to improve the microenvironments in and around the wound in an effort to enhance healing. Specifically, the present invention comprises application of tissue and cells culture nutrient media, such as minimum essential media, supplemented with insulin and/or with substances exhibiting insulin-like activity, such as cinnamon or cinnamon extracts including but not limited to MHCP. The media is applied to the wound to stimulate the viable cells in the wound bed and the adjacent cells in the periphery of the wound to proliferate and grow into the wound in order to achieve wound closure.
    Type: Application
    Filed: April 12, 2011
    Publication date: July 19, 2012
    Inventor: Ella Lindenbaum
  • Publication number: 20120177744
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 12, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Publication number: 20120171130
    Abstract: A composition is able to treat plant and animal diseases and includes a therapeutically effective amount of an encapsulated ionic mineral complex and a pharmaceutically acceptable carrier. The composition may also include other inert ingredients, botanical extracts and vitamin and mineral supplements.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 5, 2012
    Inventor: John Wayne Kennedy
  • Publication number: 20120148648
    Abstract: A composition comprising a pigment particle that is coated with a cationic material and isopropyl titanium triisostearate. The pigment particle can be included in a cleansing composition for deposition on a surface, such as skin.
    Type: Application
    Filed: August 31, 2009
    Publication date: June 14, 2012
    Applicants: Kobo Products Inc., Cologate-Palmolive Company
    Inventors: Yun Shao, David Schlossman, Neringa Kontrimiene, Ariel Haskel
  • Publication number: 20120141448
    Abstract: Phosphatidic acid is administered orally to increase muscle mass and strength in exercising mammals. Phosphatidic acid is administered orally to aging, bedridden or cachectic patients to improve nitrogen balance. The preferred form of phosphatidic acid for administration is phosphatidic acid-enriched lecithin. Creatine is co-administered orally to increase the muscle-building and strength effect. Other suggested additives include nutritional and herbal supplements, micronutrients and hormones.
    Type: Application
    Filed: November 23, 2011
    Publication date: June 7, 2012
    Inventors: Lorenzo De Ferra, Marvin Heuer, Scott Hagerman, Martin Purpura, Ralf Jäger
  • Publication number: 20120128794
    Abstract: Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.
    Type: Application
    Filed: November 18, 2011
    Publication date: May 24, 2012
    Applicant: NUTRITION 21, INC.
    Inventor: James R. Komorowski
  • Publication number: 20120100228
    Abstract: The embodiments disclosed herein relate to compositions for enhancing brain glucose transporters, such as GLUT1 and GLUT3, and methods of treating and/or preventing diseases or disorders associated with the regulation GLUT1 and GLUT3. Also provided are compositions that include chromium and an agent that targets the brain or the central nervous system. Further provided are improved methods of delivering therapeutic agents that target the brain and/or central nervous system.
    Type: Application
    Filed: June 30, 2010
    Publication date: April 26, 2012
    Inventor: James R. Komorowski