Chlorate Patents (Class 424/662)
  • Patent number: 11672798
    Abstract: The present invention provides a combination comprising ciprofloxacin, or a pharmaceutically acceptable salt thereof, and fluocinolone acetonide for use in the prevention and/or treatment of an ocular disease, wherein the prevention and/or treatment comprises the topical administration of the combination. The invention also provides an ophthalmic topical pharmaceutical composition comprising the combination together with at least one ophthalmically acceptable excipient, diluent, or carrier, for use in the prevention and/or treatment of an ocular disease, wherein the prevention and/or treatment comprises the topical administration of the composition.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: June 13, 2023
    Assignee: LABORATORIOS SALVAT, S.A.
    Inventors: Sandra Marchán Sancho, Francisca Toribio Santisteban, María Isabel Delgado Gañán
  • Publication number: 20150140012
    Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.
    Type: Application
    Filed: November 18, 2014
    Publication date: May 21, 2015
    Applicant: Nuvo Research AG
    Inventors: Mathias Brosz, Friedrich-Wilhelm Kuhne, Klaus Blaszkiewitz, Thomas Isensee
  • Patent number: 8993000
    Abstract: Provided is an efficient method of inducing differentiation of a pulp cell into an odontoblast. Also provided is an agent for inducing differentiation capable of inducing differentiation into an odontoblast efficiently. The method of inducing differentiation of a pulp cell into an odontoblast includes using a substance capable of activating a Wnt signaling pathway. Further, the agent for inducing differentiation includes a substance capable of activating a Wnt signaling pathway. Specifically, the substance capable of activating a Wnt signaling pathway is any one selected from sodium perchlorate, sodium perchlorate, lithium chloride, Norrin, and R-Spondin2.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: March 31, 2015
    Assignee: National University Corporation Okayama University
    Inventors: Takashi Yamashiro, Hiroshi Kurosaka, Noriaki Kawanabe
  • Publication number: 20140335173
    Abstract: The present invention relates to novel release capsules, particularly for protecting moisture-sensitive materials, particularly compositions for production of chlorine dioxide. The invention also relates to methods of manufacture of such release capsules, uses of such release capsules, and products comprising them.
    Type: Application
    Filed: November 27, 2012
    Publication date: November 13, 2014
    Inventors: Robert Wengeler, Jing Dreher, Andrew Patrick Full
  • Publication number: 20140205683
    Abstract: The invention is directed to a method for preventing nasolacrimal duct obstruction (NLDO) in a patient receiving high dose radioactive iodine for treatment of cancer. The method includes administering an effective amount of perchlorate anion to the eyes of the patient.
    Type: Application
    Filed: March 25, 2014
    Publication date: July 24, 2014
    Inventor: Kenneth Eli Morgenstern
  • Publication number: 20130323327
    Abstract: The invention is directed to a method for preventing nasolacrimal duct obstruction (NLDO) in a patient receiving high dose radioactive iodine for treatment of cancer. The method includes administering an effective amount of perchlorate anion to the eyes of the patient.
    Type: Application
    Filed: August 8, 2013
    Publication date: December 5, 2013
    Inventor: Kenneth Eli Morgenstern
  • Publication number: 20130295200
    Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.
    Type: Application
    Filed: April 5, 2013
    Publication date: November 7, 2013
    Inventor: Nuvo Research AG
  • Patent number: 8568759
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 29, 2013
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker
  • Publication number: 20130233696
    Abstract: Source water is treated by mixing a first component selected from the group comprising neutralized phosphonic acid compounds, neutralized phosphonate compounds, neutralized derivatives of phosphorus, neutralized anti-scalent polymers, and mixtures thereof, a second component from the group comprising chlorite salt and chlorate salt is admixed to the mixture of the water and the first component, and water. The water and the first and second components are present in amounts sufficient to form a stable liquid composition in which there is substantially no conversion of the second component to chlorine dioxide.
    Type: Application
    Filed: October 4, 2012
    Publication date: September 12, 2013
    Inventor: Carl E. Iverson
  • Patent number: 8518456
    Abstract: Disclosed are compositions related to a substantially non-cytotoxic chlorine dioxide solution. The solution may be a thickened fluid composition. Also disclosed are methods of making and using a substantially non-cytotoxic thickened fluid compositions or solutions comprising chlorine dioxide solution. An oxidizing composition of reduced irritation is also disclosed.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: August 27, 2013
    Assignee: BASF Corporation
    Inventors: Barry Keven Speronello, Frank S. Castellana, Linda Hratko
  • Publication number: 20130177629
    Abstract: The present application includes liposomes and liposomal compositions that comprise chlorite, chlorate or a mixture thereof entrapped inside the liposome core, methods for their preparation and methods of use, in particular as medicaments.
    Type: Application
    Filed: December 21, 2012
    Publication date: July 11, 2013
    Applicant: Nuvo Research GmbH
    Inventor: Nuvo Research GmbH
  • Publication number: 20120294849
    Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.
    Type: Application
    Filed: July 27, 2012
    Publication date: November 22, 2012
    Inventors: Mathias Brosz, FRIEDRICH WILHELM KUHNE, KLAUS BLASZKIEWITZ, THOMAS ISENSEE
  • Publication number: 20120288488
    Abstract: Compositions and methods for preventing or controlling bacteria, viruses and parasitic growths that cause diarrhea, pneumonia and septicemia in animals comprising a biocidal system comprised of a primary biocide and a pH buffer component; a cationic or ionic surfactant having an HLB of from about 5 to about 30; a thickening agent; and an aqueous based carrier.
    Type: Application
    Filed: January 9, 2012
    Publication date: November 15, 2012
    Applicant: NOBLE ION, LLC
    Inventors: Burt R. Sookram, John W. Veenstra
  • Publication number: 20120231091
    Abstract: Provided is an efficient method of inducing differentiation of a pulp cell into an odontoblast. Also provided is an agent for inducing differentiation capable of inducing differentiation into an odontoblast efficiently. The method of inducing differentiation of a pulp cell into an odontoblast includes using a substance capable of activating a Wnt signaling pathway. Further, the agent for inducing differentiation includes a substance capable of activating a Wnt signaling pathway. Specifically, the substance capable of activating a Wnt signaling pathway is any one selected from sodium perchlorate, sodium perchlorate, lithium chloride, Norrin, and R-Spondin2.
    Type: Application
    Filed: November 16, 2010
    Publication date: September 13, 2012
    Applicant: National University Corporation Okayama University
    Inventors: Takashi Yamashiro, Hiroshi Kurosaka, Noriaki Kawanabe
  • Publication number: 20120207851
    Abstract: A composition for producing a biocide solution upon contact with water, the composition comprises at least a hydrogen peroxide donor and polyoxychlorine donor. The biocide solution forms reactive oxygen species when contacted by microorganisms, proteinaceous substances, and reducible organic based contaminants.
    Type: Application
    Filed: February 14, 2011
    Publication date: August 16, 2012
    Inventor: Roy W. Martin
  • Publication number: 20120195974
    Abstract: The invention disclosed in this document concerns controlling mealybugs.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Mayank Yadav, Suresh Ramachandran, Sanjoy Kundu
  • Patent number: 8168208
    Abstract: A method is disclosed for the generation of bone tissue by the preparation and the application to bone defect sites of a resorbable silica-calcium phosphate bioactive composite (SCPC) that finds utility as a bone tissue engineering scaffold. The resorbable silica-calcium phosphate bioactive composite can be applied directly to bone defect or can be employed as a bioactive coating on implants to facilitate bone growth around the implant. The resorbable silica-calcium phosphate bioactive composite is prepared from a mixture of a silica salt in an amount to provide between about 0.31 moles and about 0.93 moles of silica and calcium phosphate, said silica salt being present in the resorbable silica-calcium phosphate bioactive composite. The mixture is thermally treated at a temperature ranging between about 130° C. to about 1200° C. to form said resorbable silica-calcium phosphate bioactive composite having a phase composition comprising a thermally treated form of silica and calcium phosphate.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: May 1, 2012
    Inventor: Ahmed El-Ghannam
  • Publication number: 20120046556
    Abstract: This application is directed to methods and kits for preventing the spread of sexually transmitted microorganisms among individuals. The present method is for the application of a medicament comprising an irrigant to an area of the body having, or which may have, a lesion resulting from, for example, a viral, bacteria or fungal infection, thereby damaging the microorganism within the lesion and preventing the organism from infecting human cells.
    Type: Application
    Filed: April 21, 2011
    Publication date: February 23, 2012
    Inventor: Robert M. Block
  • Patent number: 8043633
    Abstract: The invention is related to methods and compositions for controlling microorganism populations in the digestive system of an animal. In an embodiment, the invention is a composition for reducing the bacterial load in the digestive tract of an animal including a saponin containing composition and an anti-microbial agent. Other embodiments are included herein.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: October 25, 2011
    Assignee: Sartec Corporation
    Inventors: Larry C. McNeff, Clayton V. McNeff
  • Publication number: 20110165266
    Abstract: A method of screening test chemicals or compounds as inhibitors of HIV replication is disclosed. In one embodiment, the method comprises the step of determining whether the test chemical or compound is a sulfonation inhibitor. In another embodiment, the invention is a method of treating an HIV infected individual to reduce HIV replication comprising the step of treating the individual with an effective amount of sulfonation inhibitor.
    Type: Application
    Filed: April 30, 2009
    Publication date: July 7, 2011
    Inventors: James W. Bruce, Paul G. Ahlquist, John A.T. Young
  • Publication number: 20110008464
    Abstract: The present invention provides methods and compositions for treating thyroid-related medical conditions. Many thyroid-related medical conditions exist that go undiagnosed and untreated. These conditions may be prevented and treated with reduced folates and vitamin B12. Administration of reduced folates and vitamin B12 will prevent or treat cerebrospinal folate deficiency, which is linked to thyroid-related medical conditions. Administration of reduced folates and vitamin B12 will also prevent or treat conditions associated with masked megaloblastic anemia and hypothyroidism, and other conditions brought upon through improper thyroid function. Additionally, it is commonplace to treat many thyroid conditions with anti-thyroid drugs or thyroid stimulating drugs. This practice alone is also responsible for causing, or not beneficially addressing, adverse conditions that can be prevented or treated through the methods and compositions discussed herein.
    Type: Application
    Filed: July 9, 2010
    Publication date: January 13, 2011
    Inventor: Linzy O. Scott, III
  • Publication number: 20100285151
    Abstract: The present invention provides methods and compositions for treating and preventing conditions characterized by infection and/or inflammation, especially of the eyes, ears, nose, and/or throat. The methods of the invention involve administering hypohalous acid to the patient, such as in the form of a composition described herein.
    Type: Application
    Filed: January 16, 2008
    Publication date: November 11, 2010
    Applicant: PURICORE, INC.
    Inventors: Keith Goldan, Claire Sampson
  • Publication number: 20100086623
    Abstract: This invention comprises a lightweight, portable chemical combination of reagents for sterilizing or disinfecting objects in the absence of electrical power or fire. The chemical combination includes a chemical oxidant with the capacity to liberate a biocidal intermediate, a chemical reductant of the oxidant with the capacity to react with the oxidant, and an effector to induce a reaction between the oxidant and reductant. In one embodiment, the oxidant comprises chlorite, the reductant comprises sulfite, and the effector comprises ascorbate. In another embodiment, the chemical combination comprises the oxidant, reductant, effector and iron-activated magnesium. When water or water solutions are added to either embodiment, the chemical combination generates heat, steam and a biocidal intermediate that can destroy contaminating microorganisms. In one embodiment, the biocidal intermediate is a halogen-based biocidal intermediate, such as chlorine dioxide.
    Type: Application
    Filed: May 26, 2009
    Publication date: April 8, 2010
    Inventors: Christopher Doona, Maria Curtin, Irwin A. Taub, Kenneth Kustin
  • Publication number: 20090092685
    Abstract: Super-oxidized water based on hypochlorous acid, such as is obtained by the electrochemical treatment of a saline solution, may be used in the treatment of leg ulcers or other open wounds. Preferably, the pH of the super-oxidized water is in a range of 4 to 7, and the water has a redox potential of >950 mV. Medicaments based on the super-oxidized water may be in liquid or gel form. The super-oxidized water is able to control the microbial population within the wound and at the same time permit cell proliferation.
    Type: Application
    Filed: August 24, 2007
    Publication date: April 9, 2009
    Inventor: Joe B. SELKON
  • Publication number: 20080299223
    Abstract: Processes and formulations using chlorate for the control of pathogenic bacteria in food and livestock. At least one formulation includes sodium chlorate in a concentration effective against E. coli and Salmonella, and is used as a rinsing/washing agent to wash fruits and vegetables, poultry products and livestock facilities.
    Type: Application
    Filed: June 4, 2008
    Publication date: December 4, 2008
    Inventors: William R. HENNING, Drew A. Vermeire
  • Publication number: 20080274211
    Abstract: The invention is related to methods and compositions for controlling microorganism populations in the digestive system of an animal. In an embodiment, the invention is a composition for reducing the bacterial load in the digestive tract of an animal including a saponin containing composition and an anti-microbial agent. Other embodiments are included herein.
    Type: Application
    Filed: July 17, 2008
    Publication date: November 6, 2008
    Applicant: SARTEC CORPORATION
    Inventors: Larry C. McNeff, Clayton V. McNeff
  • Patent number: 7416742
    Abstract: The invention is related to methods and compositions for controlling microorganism populations in the digestive system of an animal. In an embodiment, the invention is a method for reducing protozoa populations in the digestive system of an animal including administering an effective amount of a saponin containing composition to the animal, and administering an effective amount of an anti-microbial agent to the animal. In an embodiment, the invention is a composition for reducing the bacterial load in the digestive tract of an animal including a saponin containing composition and an anti-microbial agent. In an embodiment, the invention is a method for reducing the bacterial load in the digestive system of an animal including administering an effective amount of a saponin containing composition to the animal.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: August 26, 2008
    Assignee: Sartec Corporation
    Inventors: Larry C. McNeff, Clayton V. McNeff
  • Patent number: 7115252
    Abstract: A method and composition for the restoration and maintenance of gingival and periodontal health are provided. The composition includes a potassium as an essential ingredient, which acts as an anti-bacterial agent. In some embodiments, the compositions include an osmotic agent other than potassium.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: October 3, 2006
    Inventor: Milton Hodosh
  • Patent number: 7105183
    Abstract: The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation. The invention also features methods of monitoring therapy by assessing blood immune cell activation before and after therapy.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: September 12, 2006
    Assignee: The Regents of the University of California
    Inventor: Michael S. McGrath
  • Patent number: 7056538
    Abstract: Sodium hypochlorite disinfectant solution having a pH of between 10.1 and 10.7 and comprising from 0.021 to 5.76% (w/v) of sodium hypochlorite and, relative to the said amount of sodium hypochlorite, not more than 2% of sodium chlorate.
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: June 6, 2006
    Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
    Inventors: Mario Pinza, Marcello Marchetti
  • Patent number: 7029705
    Abstract: A method is disclosed of practicing nasal hygiene comprising the steps of applying to a person's nostril a non-irritating hygienic composition consisting essentially of a product of compounding under homogenizing conditions water, 0.01% to 5% by weight, as chlorine dioxide, of a source of chlorine dioxide; 0.01% to 3% by weight of at least one olfactory stimulant, 0 to 5% by weight of at least one fixative compound less volatile than the olfactory stimulant 0.1 to 2.5% by weight of at least one inorganic salt selected from the group consisting of alkali metal chloride, alkali metal bicarbonate, and alkali metal chlorate; and 0.0002 to 0.006% (as aluminum) by weight of at least one water soluble aluminum compound, provided that the total concentration of inorganic salt is in the range from 0.6% by weight to 2.5% by weight, holding the composition within the nostril for a hygienic holding period, and discharging the composition from the treated nostril.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: April 18, 2006
    Inventor: Allan H. Fuhr
  • Patent number: 7014871
    Abstract: An iodine preparation composition suitable for use on wounds comprising an iodide source, an oxidant and a buffer characterized in that the iodide is held separately from the oxidant until the point of use, and that the buffer is capable of maintaining the pH of the composition at between pH 45 and pH 6 so that iodine is generated at a physiologically acceptable dose rate.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: March 21, 2006
    Inventors: Dave Parsons, Elizabeth Jacques, Philip Bowler
  • Patent number: 6982097
    Abstract: This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using the biocidal compositions for the disinfection of water that may contain microorganisms and biofilms.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: January 3, 2006
    Assignee: Sani-Care Salon Products, Inc.
    Inventors: Su Mingzhong, Long Truong Hoang, Linh Truong Hoang
  • Patent number: 6962714
    Abstract: The present invention relates to antimicrobial compositions including a critical, near critical, or supercritical (densified) fluid and an antimicrobial agent, to methods of forming these compositions, and to methods employing these compositions. An antimicrobial agent can be generated in the presence of a densified fluid, for example, by reacting an oxidizing agent with a precursor to the antimicrobial agent.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: November 8, 2005
    Assignee: Ecolab, Inc.
    Inventors: Robert D. P. Hei, Keith E. Olson, Robert J. Ryther, Richard K. Staub
  • Patent number: 6908628
    Abstract: Wide spectrum disinfecting and antiseptic composition for use in the fields of human medicine, veterinary science and industry, characterized because it includes: Hydrogen peroxide, lactic acid and halogen salts (Br, I) and/or salts of heavy metals (for example, silver halides) with surfactant agents, either cationic, like chlorhexidine and/or quaternary ammonium salts, like didecyl-methyl-polyoxy-ethyl-ammonium propionate, chlorides of ammonium or compounds of ammonium propylamide or anionic, like lauryl sulphate, dodecyl sulphate or alkyl succinic salts, with suitable excipients, some of which may be ethyl or isopropyl alcohol, chlorhexidine, non-chlorinated quaternary ammonium salts, like didecyl-methyl-polyoxy-ethyl-ammonium propionate, combined or not with iodine, and/or its salts, together with excipients, some of which may be ethyl or isopropyl alcohol.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: June 21, 2005
    Assignee: OFTRAI, S.L.
    Inventor: Rafael Herruzo Cabrera
  • Patent number: 6814984
    Abstract: The present invention is directed to frozen biocidal compositions. Specifically, the biocidal compositions comprise a frozen aqueous solution of a plurality of ions selected from the group consisting of halide and oxyhalide ions. The frozen biocidal compositions are useful in preserving or extending the shelf-life of perishable articles.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: November 9, 2004
    Assignee: Clean Water International LLC
    Inventors: David C. Rose, Lawrence J. Ventura
  • Publication number: 20040137079
    Abstract: Stable ophthalmic formulations comprising hyaluronic acid (sodium hyaluronate) as the primary active demulcent ingredient, stabilized oxy-chloro complex (available commercially as OcuPure(tm) from Advanced Medical Optics, Purite® from Allergan, and Purogene from Biocide) for preservative efficacy, balanced salts mimicking the tear film, and sodium borate as a buffer are disclosed. In one embodiment, preferred stable formulations may be used in the human eye with or without contact lenses. In another embodiment preferred formulations may also be used as a storage and conditioning solution for contact lenses following disinfection.
    Type: Application
    Filed: January 7, 2004
    Publication date: July 15, 2004
    Inventors: James N. Cook, Stanley W. Huth
  • Patent number: 6761911
    Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the compound Xm(ClO3)n, wherein X is a cationic moiety and m and n are independently selected from integers necessary to provide a net valency of 0. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, and Clostridia species.
    Type: Grant
    Filed: October 3, 2002
    Date of Patent: July 13, 2004
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Robin C. Anderson, David J. Nisbet, Larry H. Stanker
  • Patent number: 6663902
    Abstract: The present invention relates to a biocidal composition, designed for the generation of chlorine dioxide, comprising at least one iodo-compound having at least one iodine atom and a source of chlorite ions. The molar ration of chlorite ions to iodine atoms is 2 or greater. The composition finds use in a variety of applications including methods of cleaning, sanitizing, deodorizing, and disinfecting various surfaces.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: December 16, 2003
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, David Daniel McSherry, Kim R. Smith, Keith E. Olson
  • Publication number: 20030133878
    Abstract: This invention relates to a composition and method for treating Legionella Pneumophila comprising an electro-chemically activated anion-contained aqueous solution.
    Type: Application
    Filed: November 13, 2002
    Publication date: July 17, 2003
    Applicant: RADICAL WATERS IP (PTY) LTD
    Inventor: Gilbert Theo Hinze
  • Publication number: 20030059483
    Abstract: Manual warewashing in common food service locations is typically performed in a multicompartment sink within three or more basins. In one basin the ware is contacted with an aqueous solution of a detergent composition. The ware is cleaned using mechanical action to remove soil. The cleaned ware is often rinsed in a subsequent sink in a potable water rinse and is then sanitized in a sanitizing solution in a subsequent basin, typically the third sink in sequence. The sanitizing solution can be rapidly depleted during periods of large volumes of hand washed ware. In order to monitor and control the concentration of the sanitizer in the sanitizer sink, we have found that even highly oxidizing hypochlorite bleaches, if adjusted to an appropriate pH, can maintain substantial sanitizing capacity while not decolorizing otherwise oxidatively sensitive dyes.
    Type: Application
    Filed: February 10, 2000
    Publication date: March 27, 2003
    Inventors: Eddie D. Sowle, Darryl C. Bowling
  • Publication number: 20030039703
    Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the compound Xm(ClO3)n, wherein X is a cationic moiety and m and n are independently selected from integers necessary to provide a net valency of 0. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, and Clostridia species.
    Type: Application
    Filed: October 3, 2002
    Publication date: February 27, 2003
    Applicant: The United States of America,as represented by the Secretary of Agriculture
    Inventors: Robin C. Anderson, David J. Nisbet, Larry H. Stanker
  • Patent number: 6506737
    Abstract: An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or powdered media. The oxidizing species can be used to reduce microbial and viral populations on a surface or object or in a body or stream of water. The invention thus finds applications as a bleach, sanitizer, oxidant, or in any other application in which an oxidizing agent can be beneficially used alone or in a formulation.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: January 14, 2003
    Assignee: Ecolab, Inc.
    Inventors: Robert D. P. Hei, Kim Smith
  • Publication number: 20020176896
    Abstract: The present invention is directed to frozen biocidal compositions. Specifically, the biocidal compositions comprise a frozen aqueous solution of a plurality of ions selected from the group consisting of halide and oxyhalide ions. The frozen biocidal compositions are useful in preserving or extending the shelf-life of perishable articles.
    Type: Application
    Filed: February 8, 2002
    Publication date: November 28, 2002
    Applicant: Bioxy, Inc.
    Inventors: David C. Rose, Lawrence J. Ventura
  • Patent number: 6475527
    Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the compound Xm(ClO3)n, wherein X is a cationic moiety and m and n are independently selected from integers necessary to provide a net valency of 0. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, and Clostridia species.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: November 5, 2002
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Robin C. Anderson, David J. Nisbet, Larry H. Stanker
  • Patent number: 6368637
    Abstract: A process for treating active viral lesions, such as herpes lesions and warts, on persons or animals, in which an active lesion containing a virus is scrubbed or debrided, an aqueous reagent solution containing neutral red and free chlorine is applied to the scrubbed lesion, and the lesion to which the reagent has been applied is exposed to ultraviolet light for a period sufficient to cause viral destruction. The invention further relates to the aqueous reagent solution containing neutral red and free chlorine.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: April 9, 2002
    Assignee: Cross Bay LLC
    Inventor: Jon Stoneburner
  • Patent number: 6106853
    Abstract: Processes for controlling pollution by: (a) devolatizing vapor phase chemical pollutants (VP's) found in effluents and other bodies and streams of gases and liquids, and (b) stabilizing substrates from which the VP's are released. The offending VP's are converted to less offensive or inoffensive materials by interaction with an appropriately formulated treating agent (VTA/C) containing a primary halogen and at least one additional ingredient selected from the following classes of constituents (optional if bromine is the primary halogen and otherwise required): oligodynamically active metals, cohalogens, adjuncts, and facilitators. The major constituent(s) may be supplied as such, or a source of the constituent may be provided. Actinic radiation can be employed to promote reactions between the VP and the VTA/C, which is often formulated as an aqueous scrubbing medium.
    Type: Grant
    Filed: March 20, 1996
    Date of Patent: August 22, 2000
    Inventors: James P. Cox, Robert W. Duffy Cox
  • Patent number: 6099855
    Abstract: The invention relates to improved methods of raising and treating food animals, which employ pH-buffered, redox-stabilized compositions comprising halide and oxyhalide ions. The compositions can be administered to food animals to effect enhanced food utilization, lower mortality, decreased nitrogen excretion, decreased dependence on antibiotics and vaccines, overall enhanced health and immunostimulation in the animals.
    Type: Grant
    Filed: June 21, 1996
    Date of Patent: August 8, 2000
    Assignee: Bioxy, Inc.
    Inventors: Jaime Mullerat, William A. Curby, David A. Hazlett, Peter Kilpatrick
  • Patent number: 6034138
    Abstract: The present invention comprises a concentrated solid or semi-solid disinfectant or sterilant composition for use in an aqueous disinfecting or sterilizing solution, comprising an oxidant and a protected glutaraldehyde such as a glutaraldehyde bisulfite addition compound (GBS): ##STR1## or a glutaraldehyde dioxime compound (GDO): ##STR2## The present invention further provides a method for disinfecting or sterilizing a surface or apparatus comprising the steps of mixing a concentrated solid or semi-solid glutaraldehyde sterilant composition comprising an oxidizing compound and a protected sterilant with water to form a solution and bringing the solution into contact with the surface or apparatus.
    Type: Grant
    Filed: November 21, 1995
    Date of Patent: March 7, 2000
    Assignee: Block Drug Company, Inc.
    Inventors: Joseph Synodis, Stuart Wilensky, Alan Halecky
  • Patent number: 6008238
    Abstract: Disclosed is a stable dilute solution composition of a 3-isothiazolone compound selected from the group consisting of 5-chloro-2-methyl-3-isothiazolone, 2-methyl-3-isothiazolone, 5-chloro-2-ethyl-3-isothiazolone, 2-ethyl-3-isothiazolone, 4,5-dichloro-2-methyl-3-isothiazolone, and mixtures thereof in water having extremely low levels of copper ion and an oxidant.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: December 28, 1999
    Assignee: Rohm and Haas Company
    Inventors: Beverly Jean El A'mma, John Robert Mattox