Abstract: Sanitizing and disinfecting compositions with relatively low levels of free available chlorine, with good effectiveness against microbes, included in a burstable pouch of a system also including a plurality of initially undosed (e.g., dry) wipes in a resealable package thereof. The composition may include less than 0.5% by weight hypochlorite or other free available chlorine level, with a pH less than 12. The composition is long term stable in the pouch, but upon bursting of the pouch and dosing of the wipes, exhibits only short-term stability. Because of the low level of hypochlorite, the dosed wipes exhibit improved surface compatibility and negligible “bleach” odor, while providing at least a 3-log reduction in C. diff population within 10 minutes.

Abstract: The present disclosure relates to biocide compositions, formulations and methods for using formulations. In particular the present disclosure relates to biocide compositions and their use in treating reverse osmosis membranes.

Abstract: Disclosed herein are embodiments of a method and system for producing a halogen gas. The method may comprise contacting a solid oxidizing agent with a vapor comprising a halide compound, to produce a gas stream comprising a halogen corresponding to the halide in the halide compound. The halide compound may be an acyl halide, such as an acetyl halide or an oxalyl halide. The oxidizing agent may be any suitable oxidizing agent, and in certain examples, potassium permanganate is used. The method may be performed under a reduced pressure. Also disclosed herein is a system suitable to perform the disclosed method. The system may comprise a reservoir, an oxidizing agent support and a gas stream outlet.

Abstract: A method and dispenser for maintaining a body of water in a swimming pool free of algae with the dispenser water mateable to a surface within a pool pump basket to deliver at least one dispersant to the pool water flowing through the pool pump basket.

Abstract: The invention relates to a method for the preparation of living, microbial samples and microorganisms for subsequent mass spectrometric measurement and evaluation. Findings which can be derived from such a measurement can particularly serve the faster identification of microorganisms in the microbial sample according to species/subspecies and/or the fast determination of resistance/sensitivity of the microorganisms to antimicrobial substances and/or the further characterization of microorganisms, for example in respect of pathogenicity, virulence and metabolism. According to a preferred embodiment of the invention, the preparation particularly takes place directly on a mass spectrometric sample support.

Abstract: This invention is directed to methods for prevention of infections by highly pathogenic viruses by applying to the nasal mucous membranes topical preparations comprising the broad-spectrum antimicrobial agent povidone-iodine.

Abstract: This disclosure relates to acidizing retarder compositions and methods of reducing the rate of carbonate dissolution in carbonate acidizing treatments of carbonate formations using the acidizing retarder compositions. The methods may include dissolving one or more retarder compounds in a solution comprising a strong acid to form acidizing retarder compositions, and introducing the acidizing retarder compositions to carbonate formations. The acidizing retarder compositions may include one or more retarder compounds and a strong acid. At least one of the one or more retarder compounds may be a poloxamer. A concentration of the strong acid in the acidizing retarder composition may be 5 weight percent or greater.

Abstract: The reaction of sodium hypochlorite with sodium bromide is slow, and commonly only part of the bromide is converted to hypobromite. Methods to accelerate the reaction by adding a regulated amount of acid to a solution comprising bleach and bromide are provided, whereby the yield of hypobromite can be increased. The amount of acid added can be predetermined based on the content of a base in the bleach, and acid can be added to neutralize the base. The amount of acid added can be based on a measured parameter of the reaction that is indicative of reaction kinetics. For example, the amount of acid can be actively controlled by measuring pH, absorbance of visible or near Ultraviolet light, or temperature of the reacting solution and adjusting acid.

Abstract: Sanitizing and disinfecting compositions with relatively low levels of free available chlorine, with good effectiveness against microbes, included in a burstable pouch of a system also including a plurality of initially undosed (e.g., dry) wipes in a resealable package thereof. The composition may include less than 0.5% by weight hypochlorite or other free available chlorine level, with a pH less than 12. The composition is long term stable in the pouch, but upon bursting of the pouch and dosing of the wipes, exhibits only short-term stability. Because of the low level of hypochlorite, the dosed wipes exhibit improved surface compatibility and negligible “bleach” odor, while providing at least a 3-log reduction in C. diff population within 10 minutes.

Abstract: Formulations for promoting honeybee health include an aqueous solution having an organic acid, one or more buffering agents, one or more coloring dyes, and one or more strains of probiotic bacteria. The formulations can be in the form of syrup additives or sprays. The formulations can have additional active ingredients, inert ingredients, or both.

Abstract: A method comprises printing a conductive ink on a substrate to form one or more electrodes and printing an electrode ink on one or more of the electrodes. The conductive and electrode inks are cured. Next, an enzyme ink layer is printed on at least one electrode, and the enzyme ink layer is cured with ultraviolet light. Each of the printing and curing processes are performed in an in-line process.

Abstract: Disclosed are antiseptic compositions for disinfecting tissues, in particular for ocular use. Methods and compositions disclosed herein include sodium chlorite, optionally in combination with a surfactant.

Abstract: An air management system for a common indoor room or space that comprises a plurality of air outflow apertures or vents, a plurality of air curtains having at least a portion of the air curtains separated from one another, a plurality of separated air suction intakes, and an air sterilization and/or air cleaning mechanism.

Abstract: Systems and methods of use of chlorine dioxide in controlled environmental agriculture settings and postharvest applications are provided. A method can comprise application of gaseous chlorine dioxide at a level effective to prevent microbial proliferation in a setting containing growing plants. A system can comprise a chemical microorganism control agent dispersal system, an airborne microorganism detection system, and a cultivation environment monitor system.

Abstract: Kits and composition comprising: (i) a thermo-responsive hydrogel characterized by a viscosity suitable for hardening after administration on a subject's skin; (ii) a bacterial growth medium; and optionally, (iii) a population of non-pathogenic viable bacteria, are provided. Methods for topically delivering a therapeutic or cosmeceutical agent such as for inhibiting or reducing growth of microorganisms on a subject's skin are further provided.

Abstract: A composition for air polishing the surface of hard dental tissue includes an abrasive first powder suitable for polishing hard dental tissue; a second powder of a gelling agent; and a third powder of a dental treatment agent.

Abstract: A method of maintaining a body of water in a usable condition through a comparative measurements of total chlorine and free chlorine in the body of water to determine if a synergistic chemical combination exists within the body of water that can effect the amount of chlorine to add to the body of water.

Abstract: Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.

Abstract: The present invention relates to compositions comprising molecular iodine and a vehicle comprising a semifluorinated alkane. The compositions of the invention may be used to treat or prevent diseases or conditions caused by, or associated with microorganisms.

Abstract: Provided is a use of a Macaranga tanarius preparation or extract for manufacturing a composition for enhancing immunity of an insect, particularly a bee. Also provided is a method for enhancing immunity of an insect, particularly a bee. The method comprises administering an effective amount of a composition of the present invention to the insect.

Abstract: A method for making an aqueous hypochlorous acid (HClO) solution includes electrolyzing a solution of sodium chloride to produce a solution of sodium hypochlorite; and producing the aqueous hypochlorous acid solution by adjusting a pH of the solution of sodium hypochlorite to a value within a range of 3 to 8 by adding a selected weak acid to the solution of sodium hypochlorite to produce a buffer including the selected weak acid and a salt of the selected weak acid.

Abstract: The present invention provides a composition of long-term constant-concentration aqueous chlorine dioxide solution including dissolved chlorine dioxide, a decomposition inhibitor for dissolved chlorine dioxide, and a pH modifier, and a method for preparing the same.

Abstract: The present invention provides methods and compositions for treating and preventing conditions characterized by infection and/or inflammation, especially of the eyes, ears, nose, and/or throat. The methods of the invention involve administering hypohalous acid to the patient, such as in the form of a composition described herein.

Abstract: The present invention provides methods for treating conditions that involve infection and/or inflammation, including acute and chronic inflammation, as well as delayed-type and immediate-type hypersensitivity. The invention in various embodiments provides methods for treating microbial infection and the associated inflammatory response, as well methods for treating inflammatory conditions that spawn or are susceptible to secondary microbial infection. Further, the invention provides methods for treating inflammation, such as chronic inflammation, without any associated microbial infection.

Abstract: The present invention relates to improved biocide compositions based on calcium fluoride which are suitable for a broad range of applications including surface disinfectants, additives to construction materials and paints, antiseptic medical and cosmetic formulations, as a crop protection product and as a fast-acting disinfectant. The biocide composition of the invention comprise at least the following components: a) calcium fluoride b) a salicylic acid ester c) at least one organic acid selected from the group comprising or consisting of cinnamic acid, rosmarinic acid, vanillic acid, ascorbic acid, abscisic acid, mandelic acid, mevalonic acid, aspartic acid, salicylic acid, fumaric acid, isocitric acid, gallic acid, quinic acid, boswellic acid, carnosic acid, chlorogene acid, caffeic acid, other hydroxycarboxylic acids, or a salt or ester thereof, or thymol or citronellal. d) a cationic polymer and/or natural sea salt or a synthetic equivalent thereof and/or a cationic tenside, e) water.

Abstract: A sterilant source for use in a portable sterilant system includes a gas-impermeable vial, a frangible ampule containing a first sterilant gas precursor material, disposed within the gas-impermeable vial, a second sterilant gas precursor material, disposed within the gas-impermeable vial and outside the ampule. The first and second sterilant gas precursor materials are selected to be mutually reactive to generate a sterilant gas. The system further includes an activation mechanism, actuatable to break the frangible ampule to release the first sterilant gas precursor material to allow it to react with the second sterilant gas precursor material to generate the sterilant gas.

Abstract: The present invention relates to a disinfectant composition comprising hydrogen peroxide in association with at least one quaternary ammonium salt, suitable for disinfecting a room and the objects that may be therein contained. The composition is further characterized by the absence of ions of heavy metals and is particularly suitable for use in a method for the disinfection of a room, which comprises the diffusion of the present disinfectant composition in the form of a dry mist, maintaining contact with the room and with the objects therein contained, so as to obtain the desired degree of disinfection.

Abstract: A method comprising: administering an effective amount of a topical dipyridamole to a subject in need thereof due to a disorder selected from the group consisting of keratitis, corneal abrasion and corneal ulcer.

Abstract: A method comprising administering an effective amount of a topical dipyridamole to a subject in need thereof due to conjunctivitis.

Abstract: A method for changing a condition of an eyelid of a mammal excluding a human, a model animal for evaluating a therapeutic or prophylactic effect against an eyelid disease obtained by the method, a method for producing the model animal, a method of screening using the model animal and a substance having a therapeutic or prophylactic effect against an eyelid disease selected by the method of screening, and a therapeutic or prophylactic agent against an eyelid disease containing the substance as an active ingredient.

Abstract: The invention described herein is directed to method of treating chronic obstructive pulmonary disease, comprising administering an effective amount of an osmolyte by at least one nasal cannula to a subject in need thereof. Also provided is a nasal cannula system for delivering an osmolyte, comprising a nebulizer and tubing having two ends, where the first end of the tubing is connected to the nebulizer and the second end of the tubing is tapered to fit in the nostril of a subject.

Abstract: This invention concerns a method for preventing and treating Colony Collapse Disorder, consisting in the use of an automated device that delivers a diet specifically calibrated for consumption by farm colonies of bees to be treated. The apparatus comprises a box-like container (10) accommodating in its interior at least one reservoir for liquid-tight, accessible from outside through a nozzle (4), an atomizing device of a liquid solution or suspension contained in the reservoir, means for the delivery (2, 1) of the liquid atomized solution or suspension into micrometric drops outside the apparatus, and a control unit programmed for timing the delivery of the solution or suspension to the outside, for the determination of the quantity of solution or suspension delivered and for emitting alarm signals in case of malfunction, the apparatus being powered DC with the energy supplied by a solar panel (5) located outside of the container.

Abstract: Described herein are chlorite formulations having a pH between about 7 and about 8.5, wherein the chlorite formulations are substantially free of deleterious non-chlorite components. Described herein are chlorite formulations, including pharmaceutical formulations, which are formulated for systemic, parenteral, or intravenous administration. Described herein are methods of preparing and methods of using the chlorite formulations described herein.

Abstract: Disclosed are pharmaceutical compositions comprising brimonidine and timolol for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for glaucoma and associated conditions such as elevated intraocular pressure in the eyes of humans.

Abstract: An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Additionally, the preservative does not generate chlorine dioxide within the pH range of 5.0-8.8. Also included are an antimicrobial ophthalmic and dermatologic compositions for direct application onto an eye or skin of a living being including from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Also included are methods for treating dryness of the eyes and skin disorders (e.g., wounds, burns, infections, ulcerations, psoriasis, etc.) and for disinfecting and cleansing contact lenses while in place upon an eye by applying the composition to the eye or to the contact lens.

Abstract: Methods are described for producing sugar from sugar-containing plant material with microbiological control, which includes treating a sugar-containing plant raw material and/or a component derived therefrom, and/or a medium containing the plant raw material and/or the component, with monochloramine. Monochloramine usage in the method can reduce loss of sugar from bacterial consumptions in the processing of sugar-containing plant materials, such as sugar beets, without causing adverse effects on the sugar product, such as the brightness of white sugar.

Abstract: The invention concerns the use of grape (Vitis vinifera) seeds extracts as agents for the treatment and prevention of plant diseases caused by pathogens, particularly by fungi and oomycetes, as well as fungicidal compositions comprising Vitis vinifera extracts for application to plants affected or liable to be affected by a pathogen, especially a fungus or oomycete.

Abstract: A biological decontamination gel, consisting of a colloidal solution comprising from 5 to 30% by mass, preferably 5 to 25% by mass, still preferably 8 to 20% by mass, based on the mass of the gel, of at least one inorganic viscosifying agent: 0.5 to 10 mol/L of gel, preferably 1 to 10 mol/L of gel, of at least one active biological decontamination agent; 0.05 to 5% by mass, preferably 0.05 to 2% by mass, based on the mass of the gel, of at least one super-absorbent polymer; 0.1 to 2% by mass, based on the mass of the gel, of at least one surfactant; and the remainder of solvent. A biological decontamination method applying this gel.

Abstract: A process for generating aqueous chlorine dioxide solutions includes adding a solid phase alkali metal chlorite, a solid phase acid, and a solid phase oxidizing agent to an aqueous solution, wherein the solid phase acid ahs a pKa less than 4. Also disclosed are compositions for producing chlorine dioxide solutions.

Abstract: The invention is directed to compositions and methods of their use as effective biocidal agents for water streams. The composition comprises a halogen source, halogen stabilizers containing a sulfur bearing species and ammonium salts/urea, and an alkali. The sulfur bearing species includes sulfamic acid or its salt equivalent. By having optimized mixing ratio of halogen to stabilizer and that of ammonium salts to sulfamic acid or sulfamate, a synergistic effect occurs which both increases the efficacy of the composition as a biocide and it avoids adverse impacts on other chemicals that are present in the water stream. Best of all the composition is easy to form and easy to introduce into a water stream of concern. Its introduction can be as simple as mixing two containers of reagent prior to introduction to the water process stream.

Abstract: A composition and methods of its use, the composition comprising: a halogen source, urea, and an additional halogen stabilizer excluding urea, optionally an alkali in a concentration sufficient to provide said composition with a pH of greater than 10; and optionally excluding a stabilized bromine compound from said composition is disclosed. Additionally, a method for reducing biological activity in a process stream is disclosed. The method comprises: providing a composition to a process stream, wherein said composition contains: a halogen, urea, and an additional halogen stabilizer excluding urea, optionally an alkali in a concentration sufficient to provide said composition with a pH of greater than 10; and optionally excluding a stabilized bromine compound from said composition. The invention is also directed to compositions and methods of their use as effective biocidal agents for water streams.

Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.

Abstract: A measure that can readily prevent arthropod-borne diseases such as malaria that are contracted by 3 to 5 hundred million people worldwide yearly and that cause death of as many as 1.5 to 2.7 million people. By spraying in advance on the skin an arthropod-borne disease preventive agent or the like including chlorine dioxide as an effective component thereof, it is possible to provide repelling effect against arthropods such as infected mosquitoes that bear malaria protozoa and also to prevent biting of the skin by the arthropod, thus reducing contraction of the arthropod-borne diseases.

Abstract: A method of manufacturing and an apparatus for making an aqueous chlorine solution having a pH between 3.0 and 6.5 and a stability such that after 6 weeks storage at 20 degrees Celsius the pH remains in the range 3.0 to 6.5 and the amount of chlorine lost from the solution is less than 10%, such that the method includes: (a) Providing a source of water having an electrical conductivity at 20 degrees Celsius of no more than 50 (and preferably no more than 4.3) ?Scm-1 (b) Reacting the water with solid calcium hypochlorite having a purity of at least 60%; and (c) Adjusting the pH to between 3.0 and 6.5.

Abstract: A method for production and storage of hypochlorous acid is disclosed. The method comprises using high purity water achieved by a combination of softening and reverse osmosis steps. The shelf life is further improved by storing the hypochlorous acid in opaque PET bottles or Nylon/PE bags or nylon bags in a box. Solutions stored in opaque PET bottles exhibit the best stability. Anticipated uses of the extended life hypochlorous acid solution include sanitizer for food contact and non-food contact surfaces, a streak-free cleaner for smooth surfaces and a cut flower life extender. Other biocide uses include water treatment in oil and gas production, cooling tower, lazy river and swimming pools, process water distribution systems, drinking water, portable humidifier, fish tanks and treatment of metalworking fluids and lubricants.

Abstract: The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later use on demand. The invention further provides methods of making the stabilized hypohalous acid solution, as well as methods of use for disinfecting mammalian tissue, including wounds and burns, disinfecting or cleansing surfaces, or treating and/or preserving food products and cut flowers, among other uses.

Abstract: A composition that includes ethylhexyl sulfate or a salt thereof, an alkylbenzenesulfonic acid or a salt thereof, and a carrier. The ethylhexyl sulfate, or salt thereof, and the alkylbenzenesulfonic acid, or salt thereof, are present in a weight ratio of at least about 1:2. The composition can be used for killing or inhibiting a microorganism or pathogen (e.g., bacteria, gram-negative bacteria, gram-positive bacteria, enteric bacteria, virus, fungus, mold, mildew or powdery mildew).

Abstract: Redox signaling gels are disclosed. Such gels include a composition with at least one reactive oxygen species (ROS) and a rheology modifier. Also presented herein is a process for making the gels which includes making the composition by taking the steps of purifying water to produce ultra-pure water, combining a salt to the ultra-pure water to create a salinated water, electrolyzing the salinated water at a temperature of 4.3 to 5.8° C. such that the electrolyzing is accomplished with an anode, cathode and power source such that the power source comprises a transformer and a rectifier and does not comprise a filter capacitor.

Abstract: According to one embodiment, a coagulant comprising calcium nitrate and an antimicrobial agent is disclosed. The coagulant may be used in the molding process to releasably bond the substrate material to the mold and to bond to the antimicrobial to the substrate material.

Abstract: The present invention is directed to a method, system and equipment for the elaboration of electrolytic chlorine oxidants, hypochlorous acid and sodium hypochlorite substances, using elements that result in an ecological process and confers a high efficiency in the production of these substances, permitting the generation of a product of very high performance and efficiency.