Calcium Containing Sulfur Compound (e.g., Calcium Sulfate, Etc.) Patents (Class 424/696)
  • Patent number: 8968465
    Abstract: A composition includes calcium sulfate hemihydrate, stearic acid, an accelerant, and a mixing solution. The composition can be injected, e.g., through a needle, and is capable of setting, e.g., in vivo, in a relatively short period of time to a relatively high hardness.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: March 3, 2015
    Assignee: Wright Medical Technology, Inc.
    Inventors: Jantzen Cole, Timothy Smith
  • Patent number: 8906111
    Abstract: Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from an artificial bone material for transplantation which contains a calcium-containing substance can be prevented effectively by subjecting the carrier to a surface treatment or adding a surface-treating agent to the carrier. It is also found that the induction of cytotoxicity can be prevented and the induction of an inflammatory response can also be prevented by using the above-mentioned carrier having controlled calcium ion elution.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: December 9, 2014
    Assignees: The University of Tokyo, Next21 K.K.
    Inventors: Yuichi Tei, Nobuo Sasaki, Shigeki Suzuki
  • Publication number: 20140348947
    Abstract: This document discloses molecules having the following formula (“Formula I”):
    Type: Application
    Filed: August 8, 2014
    Publication date: November 27, 2014
    Applicant: Dow AgroSciences LLC
    Inventors: Tony K. Trullinger, Ricky Hunter, Negar Garizi, Maurice C. H. Yap, Ann M. Buysse, Dan Pernich, Timothy C. Johnson, Kristy Bryan, Carl DeAmicis, Yu Zhang, Noormohamed M. Niyaz, CaSandra Lee McLeod, Ronald Ross, JR., Yuanming Zhu, Peter Lee Johnson, Joseph D. Eckelbarger, Marshall H. Parker
  • Publication number: 20140205685
    Abstract: A method and medicine for treating melanoma, BCC (basal cell carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, comprising applying or injecting to an infected skin area of a patient diagnosed with melanoma, BCC (basal cell carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, a treatment regimen that includes periodic doses of a molecular combination of emodin and digoxin and/or an herbal combination of Da Huang and Sheng Di Huang.
    Type: Application
    Filed: December 2, 2013
    Publication date: July 24, 2014
    Applicant: Sirbal, Ltd.
    Inventor: Nadav Shraibom
  • Publication number: 20140161901
    Abstract: Dental compositions are disclosed. A dental composition can include a reaction produce of a reaction mixture comprising a first mixture and a second mixture. The first mixture can include a ceramic based biomaterial, and the second mixture can include mineral trioxide aggregate and a phosphoric acid monomer.
    Type: Application
    Filed: December 10, 2013
    Publication date: June 12, 2014
    Applicant: Zimmer Dental, Inc.
    Inventors: Jin Whan Lee, Hai Bo Wen, Jeffrey Bassett, Mike Warner
  • Publication number: 20140134227
    Abstract: A composition includes calcium sulfate hemihydrate, stearic acid, an accelerant, and a mixing solution. The composition can be injected, e.g., through a needle, and is capable of setting, e.g., in vivo, in a relatively short period of time to a relatively high hardness.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: WRIGHT MEDICAL TECHNOLOGY, INC.
    Inventors: Jantzen Cole, Timothy Smith
  • Publication number: 20140134251
    Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.
    Type: Application
    Filed: October 23, 2013
    Publication date: May 15, 2014
    Applicant: PULMATRIX, INC.
    Inventors: Michael M. LIPP, Robert W. CLARKE, David L. HAVA, Richard BATYCKY, John HANRAHAN
  • Publication number: 20140093571
    Abstract: A kneadable and moldable bone-replacement material includes a mixture of calcium-containing ceramic particles and a hydrogel or a substance which can be swelled into a hydrogel. The ceramic particles are of fully synthetic origin and the individual ceramic particles have a structure which is at least partially cohesive and porous. In addition, the majority of the ceramic particles have a non-spheric shape.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 3, 2014
    Inventors: Giancarlo Rizzoli, Thierry Stoll, Reto Luginbuhl, Marc Bohner
  • Patent number: 8685464
    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a ?-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
    Type: Grant
    Filed: January 18, 2007
    Date of Patent: April 1, 2014
    Assignee: Agnovos Healthcare, LLC
    Inventors: Jon P. Moseley, Michael E. Carroll, Jonathan D. McCanless
  • Patent number: 8657952
    Abstract: A composition includes calcium sulfate hemihydrate, stearic acid, an accelerant, and a mixing solution. The composition can be injected, e.g., through a needle, and is capable of setting, e.g., in vivo, in a relatively short period of time to a relatively high hardness.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: February 25, 2014
    Assignee: Wright Medical Technology, Inc.
    Inventors: Jantzen Cole, Timothy Smith
  • Publication number: 20140037760
    Abstract: The present invention relates to methods of treating cancer through stasis induction, wherein said stasis-inducing treatment results in reduced blood flow to the cells of said cancer, leading to diminished tumor growth and/or tumor death. In one embodiment, the stasis-inducing treatment comprises administering a therapeutically effective amount of a chalcogenide, salt, or prodrug thereof. The method of treating cancer may optionally comprise an additional step of withdrawing a portion of blood from said patient, such that blood flow to said cancer is further reduced or eliminated. In additional embodiments, the method of treating cancer may optionally comprise an additional step of diverting a portion of the blood flow in said patient, such that blood flow to said cancer is further reduced or eliminated.
    Type: Application
    Filed: March 19, 2012
    Publication date: February 6, 2014
    Inventor: Jeff Thramann
  • Patent number: 8632796
    Abstract: A bone implant composition, the composition comprising calcium sulphate and slowly soluble source of calcium, orthophosphate and hydroxyl ions. The composition may be provided in powder or granulated form.
    Type: Grant
    Filed: January 20, 2009
    Date of Patent: January 21, 2014
    Assignee: Biocomposites Limited
    Inventor: John Joseph Cooper
  • Publication number: 20130330416
    Abstract: Technologies are described herein for styptic compounds comprising a hemostatic or styptic agent suspended within a hydrophobic carrier medium. Example carrier mediums may include waxes, lipids, oils, or combinations thereof. The compound may be a semisolid at room temperature and soft enough to be easily dispensed and formed into or onto bleeding tissue of an animal or human. The hydrophobic qualities of the carrier medium can protect the styptic agent from absorbing moisture. The carrier medium can mechanically support positioning treatments adjacent to the bleeding tissue. The carrier medium can further serve to mechanically seal the tissue to aid in hemostasis while also protecting the tissue from debris and contamination. The carrier medium can aid in maintaining moisture within the tissue. Slurry-based manufacturing processes can support a substantially homogeneous dispersal of styptic agent throughout the carrier medium.
    Type: Application
    Filed: June 8, 2012
    Publication date: December 12, 2013
    Inventor: Robert J. Greenwald
  • Patent number: 8563053
    Abstract: A composition and method for treating a bone condition of an animal. The composition includes a nanoformulation of active ingredients. The active ingredients include Lepidium Sativum or other Lepidium extracts, calcium, vitamin D, and antioxidants. The method for treating a bone condition includes introducing the composition into the animal.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: October 22, 2013
    Inventors: Shaker A. Mousa, Mohammed H. Qari, Mohammed S. Ardawi
  • Publication number: 20130202682
    Abstract: Compositions of synthetic matrix vesicles with mineralization relevant ions which direct mineralization of a biomimetic mineral phase and methods for use thereof are provided.
    Type: Application
    Filed: January 24, 2013
    Publication date: August 8, 2013
    Applicant: The Trustees of Columbia University in the City of New York
    Inventor: The Trustees of Columbia University in the City of New York
  • Publication number: 20130190178
    Abstract: The pesticidal compositions comprising synergistic mixtures of O,O-dimethyl S-phthalimidomethyl phosphorodithioate or suitable salt forms thereof, and at least one benzoylurea based chitin inhibiting compound or suitable salt forms thereof, and especially preferably one or more of (RS)-1-[3-chloro-4-(1,1,2-trifluoro-2-trifluoromethoxyethoxy)phenyl]-3-(2,6-di-fluorobenzoyl)urea (also interchangeably referred to as “novaluron”) or suitable salt forms thereof, and 1-(2-chlorobenzoyl)-3-(4-trifluoromethoxyphenyl)urea (also interchangeably referred to as “triflumuron”) or suitable salt forms thereof, for the control of undesired pests, preferably for the control of Codling moths in fruit. Methods of controlling the incidence of undesired pests, via treatment regimens providing synergistic amounts of each of the foregoing compounds, are also disclosed.
    Type: Application
    Filed: August 1, 2011
    Publication date: July 25, 2013
    Applicant: GOWAN COMERCIO INTEMACIONAL E SERVICOS LIMITADA
    Inventors: Tak Wai Cheung, Gary Louis Melchior, Eric James McEwen, Joszef Selmeczi, Jacques-Laurent Anslaux
  • Patent number: 8404262
    Abstract: The present invention relates to improved compositions for controlling marine pest anemones, to methods of application of same, and to kits for the convenient dispensing of such compositions.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: March 26, 2013
    Assignee: Red Sea Fish Pharm Ltd.
    Inventor: Sharon Ram
  • Publication number: 20130045262
    Abstract: Disclosed are a sedative for external use, and sedative sheet, and textile, clothing, wall material, and hyperthermia equipment, brain vitalization sheet, brain vitalization small pillow which are with high productivity, adaptive for various shape and various treatment style for patients with pain, and with high treatment effect, comparing with conventional sedative for external use. A sedative for external use 10 is provided which is a bag 2 containing desert rose powder 1 prepared by pulverizing desert rose.
    Type: Application
    Filed: October 29, 2010
    Publication date: February 21, 2013
    Inventor: Nobuhiro Maruyama
  • Publication number: 20130022661
    Abstract: A bio-remodable augmentation device including an implantable member configured for maintaining space in a bone defect. The implantable member is formed from a bio-remodable composite having structural properties so as to aid in the generation of new bone tissue and eventually be reabsorbed in the newly formed bone tissue. This structural and bio-remodable implant reduces, if not eliminates, the need to remove the implantable member from the patient once new bone tissue is formed. A kit including the implantable devices and bone growth material is disclosed. Methods of use are also disclosed.
    Type: Application
    Filed: July 21, 2011
    Publication date: January 24, 2013
    Applicant: Warsaw Orthopedic, Inc.
    Inventor: William F. McKay
  • Publication number: 20120283100
    Abstract: The invention disclosed in this document concerns controlling planthoppers.
    Type: Application
    Filed: May 4, 2012
    Publication date: November 8, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Agamananda Roy, Sanjoy Kundu, Suresh Ramachandran
  • Publication number: 20120283099
    Abstract: The invention disclosed in this document concerns controlling planthoppers.
    Type: Application
    Filed: May 4, 2012
    Publication date: November 8, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Agamananda Roy, Sanjoy Kundu, Suresh Ramachandran
  • Publication number: 20120263797
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 18, 2012
    Applicant: BIOS2 Medical, Inc.
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Patent number: 8287919
    Abstract: The current invention involves compositions and methods for killing various soft-bodied animals of interest (more specifically, Coqui frogs and Coqui frog eggs are targeted) with a low pH adjusted pesticide. The method involves contacting the soft-bodied animal of interest with the low pH adjusted pesticide, wherein the pesticide is a propionic acid composition, a citric acid composition, an Acidic Calcium Sulfate (ACS) composition, or combination thereof. The preferred pesticide composition has a working concentration that is less than about 15% (w/v), and a pH less than about pH 2.5, which has a lethal effect on Coqui frogs, but is less phytotoxic than higher concentration pesticides. The method includes spraying any of the pH adjusted pesticides thoroughly an area inhabited by the soft-bodied animals of interest, which includes the under brush, under bushes, and typically any hiding places.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: October 16, 2012
    Inventor: David P. Davis
  • Publication number: 20120207808
    Abstract: An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be “matched” to provide the implant with similar physical and/or chemical properties as the host tissue.
    Type: Application
    Filed: February 10, 2011
    Publication date: August 16, 2012
    Inventors: Douglas G. Evans, Scott M. Goldman, Russell T. Kronengold
  • Publication number: 20120195982
    Abstract: An injectible, biocompatible synthetic bone growth composition comprising a mineralized collagen and a calcium sulfate component. The composition is formed into injectible formulation that may be provided at the site of a skeletal defect via minimally invasive manner. An osteoinductive component may be further added, either before or after forming the unitary article. The composition may be formulated as a paste or putty and facilitates bone growth and/or repair.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 2, 2012
    Applicant: Beijing Allgens Medical Science & Technology Co., Ltd.
    Inventors: Eric G. Hu, Kun Hu, Chenguang Liu, Zonggang Chen, Fuzai Cui
  • Patent number: 8226986
    Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: July 24, 2012
    Assignee: Ikaria, Inc.
    Inventors: Kevin J. Tomaselli, Paul A. Hill, Thomas L. Deckwerth, Edward A. Wintner, Csaba Szabo
  • Publication number: 20120141607
    Abstract: The present invention relates to a new composition and methods for preventing the transmission of enterohemorrhagic E. coli and other foodborne pathogens to farm animals. In accordance with one embodiment, a composition comprising lactic acid and acidic calcium sulfate, and a compound selected from the group consisting of caprylic acid, sodium benzoate, butyric acid and chlorine dioxide is provided as an inhibitor of the growth of enterohemorrhagic E. coli and other foodborne pathogens.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 7, 2012
    Applicant: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION
    Inventors: Michael P. Doyle, Tong Zhao
  • Publication number: 20120135091
    Abstract: The present invention concerns the use of active compounds, including chalcogenides and sirtuin-modulating compounds, either alone or in combination for increasing or enhancing survivability and/or longevity in biological matter. In general aspects, the chalcogenides and other active compounds may modulate one or more sirtuin proteins. It includes compositions, methods, articles of manufacture and apparatuses for enhancing survivability in any of these biological materials, so as to preserve and/or protect them. In specific embodiments, there are also therapeutic methods and apparatuses for aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer using the active compounds described.
    Type: Application
    Filed: January 18, 2008
    Publication date: May 31, 2012
    Inventors: Mark B. Roth, Dana L. Miller
  • Publication number: 20120107414
    Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.
    Type: Application
    Filed: March 26, 2010
    Publication date: May 3, 2012
    Applicant: Pulmatrix, Inc.
    Inventors: Michael M. Lipp, Robert W. Clarke, David L. Hava, Richard Batycky, John Hanrahan
  • Publication number: 20120100119
    Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.
    Type: Application
    Filed: December 8, 2011
    Publication date: April 26, 2012
    Applicant: Momentive Performance Materials Inc.
    Inventors: George A. Policello, Mark D. Leatherman, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
  • Publication number: 20120076742
    Abstract: A topical drug delivery system for use as a self-medication delivery system, formed as a multi-functional hygroscopic solution comprising a non-hygroscopic first chemical penetration enhancer, a hygroscopic second chemical penetration enhancer and an anti-oxidizing dispersant mixable in solution with the first and second chemical penetration enhancers and an active pharmaceutical ingredient, said dispersant being in a weight percent of the solution of between 3% and 10% and being suitable for providing multiple secondary therapeutic effects by interaction with the active pharmaceutical ingredient to ensure substantial homogenous distribution of the selected active pharmaceutical ingredient in the solution during delivery of the solution to all areas of the mammalian tissue location and by further reducing the water activity level of the solution.
    Type: Application
    Filed: April 21, 2011
    Publication date: March 29, 2012
    Inventors: D. Howard Phillips, Steven Keough
  • Patent number: 8137705
    Abstract: The present invention relates to a new composition and methods for preventing the transmission of enterohemorrhagic E. coli and other foodborne pathogens to farm animals. In accordance with one embodiment, a composition comprising lactic acid and acidic calcium sulfate, and a compound selected from the group consisting of caprylic acid, sodium benzoate, butyric acid and chlorine dioxide is provided as an inhibitor of the growth of enterohemorrhagic E. coli and other foodborne pathogens.
    Type: Grant
    Filed: January 25, 2006
    Date of Patent: March 20, 2012
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Michael P. Doyle, Tong Zhao
  • Publication number: 20110311643
    Abstract: Supplemented matrices comprising a PTH releasably incorporated therein, optionally containing a granular material, which are used to heal bone fractures, particularly bone fractures with a risk of becoming delayed unions or non-unions, are described herein. The PTH is incorporated either through covalent linkage to the matrix or through non-covalent interaction with the matrix and/or the granules. These supplemented matrices decrease the time of healing compared to autograft and or trigger healing of bone fractures which otherwise would not heal. The matrices are biocompatible, preferably biodegradable, and can be formed in vitro or in vivo, at the time of implantation. The PTH may be a part of a fusion peptide. PTH can be incorporated into the matrices with full retention of its bioactivity. PTH can be releasably incorporated in the matrix.
    Type: Application
    Filed: June 23, 2011
    Publication date: December 22, 2011
    Inventors: Jason Schense, John Watson, Isabelle Arrighi
  • Publication number: 20110311653
    Abstract: Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to result in blood vessel growth in the ischemic tissue. The subject can be diagnosed as having a medical condition that results in persistent or recurring restriction of blood supply to a tissue, for example, peripheral artery disease, diabetes, atherosclerotic cardiovascular disease or defective wound healing. The methods can include the step of identifying a suitable subject.
    Type: Application
    Filed: November 17, 2008
    Publication date: December 22, 2011
    Applicants: THE UAB RESEARCH FOUNDATION, LOUISIANA STATE UNIVERSITY
    Inventors: Christopher Kevil, David Lefer, Rakesh Patel
  • Publication number: 20110280958
    Abstract: The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a metal salt (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. In particular the combinations according to the invention are useful to obtain plants with greener leaf color.
    Type: Application
    Filed: April 14, 2011
    Publication date: November 17, 2011
    Applicant: Bayer CropScience AG
    Inventors: Thomas Seitz, Ulrike Wachendorff-Neumann
  • Publication number: 20110268782
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Application
    Filed: July 13, 2011
    Publication date: November 3, 2011
    Applicant: WARSAW ORTHOPEDIC, INC.
    Inventors: David Knaack, John Winterbottom, David Kaes, Todd Boyce, Lawrence A. Shimp
  • Publication number: 20110251067
    Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.
    Type: Application
    Filed: June 22, 2011
    Publication date: October 13, 2011
    Applicant: Momentive Performance Materials Inc.
    Inventors: George A. Policello, Mark D. Leathermani, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
  • Publication number: 20110250259
    Abstract: Breast cancer is a common cancer in women. Early diagnosis and treatments are vital for better outcomes. This formula consists of a liquid anti-disease anti-cancer formula that can be delivered to the source where breast cancer begins. Method of treating breast disease, including cancer, with a formula and a means of delivery with a topical, intraductal, ductal, and/or intraductal infusion to prevent the formation of cancer or precursors to cancer or atypia or other form of abnormal breast tissue or to treat breast diseases of all kinds. May include homeopathic remedies to be used topically or inside the breast with a delivery method to those regions and may be processed with or without photonic programming or an ionic delivery system for greater effectiveness and use against degenerative diseases or cancerous or precancerous diseases, precursors of breast disease, inflammatory breast disease, or accumulation of toxins in the breast tissue.
    Type: Application
    Filed: April 12, 2010
    Publication date: October 13, 2011
    Inventor: Kevin Buckman
  • Patent number: 8025903
    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a ?-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: September 27, 2011
    Assignee: Wright Medical Technology, Inc.
    Inventors: Jon P. Moseley, Michael E. Carroll, Jonathan D. McCanless, Olaf Schulz, Andy Fronk
  • Publication number: 20110212186
    Abstract: The present invention relates to a composition, use and a method for reducing inflammation and promoting tissue repair or tissue regeneration through a synergistic effect of T-ChOS and Glucosamine and/or N-acetyl glucosamine systemically or locally administered in humans and other mammals in need thereof.
    Type: Application
    Filed: July 20, 2009
    Publication date: September 1, 2011
    Inventors: Johannes Gislason, Jon M. Einarsson, Chuen How Ng
  • Publication number: 20110189296
    Abstract: The invention relates to a composition for a bone substitute that includes powdery or populated porous bio-glass and powdery alpha hemihydrate calcium sulphate. The invention also relates to an injectable composition for forming a bone substitute that includes said composition of powdery or granulated porous bio-glass and powdery alpha hemihydrate calcium sulphate, with 10 to 50 wt % of added water.
    Type: Application
    Filed: August 24, 2009
    Publication date: August 4, 2011
    Applicant: NORAKER
    Inventors: André Rauïs, Rachid Zenati
  • Patent number: 7976876
    Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and a quinone, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: July 12, 2011
    Assignee: Well-Being Biochemical Corp.
    Inventors: Jih-ru Hwu, Shwu-chen Tsay
  • Publication number: 20110144764
    Abstract: The present disclosure relates to a bone graft material and a bone graft implant formed from the material. In some embodiments, the bone graft implant comprises a porous matrix having a plurality of overlapping and interlocking bioactive glass fibers and a plurality of pores dispersed throughout the matrix, whereby the fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the pores are characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter. The implant may be formed into a desired shape for a clinical application. The embodiments may be employed to treat a bone defect. For example, the bone graft material may be wetted and molded into a suitable form for implantation. The implant may then be introduced into a prepared anatomical site.
    Type: Application
    Filed: October 28, 2010
    Publication date: June 16, 2011
    Applicant: PROSIDYAN INC.
    Inventors: CHARANPREET S. BAGGA, Hyun W. Bae, Thomas E. Day
  • Publication number: 20110135747
    Abstract: Provided are methods of topical application of an aqueous homeopathic composition for treating various ailments and injuries, including deep tissue wounds and surgical wounds. The aqueous homeopathic composition is formulated in a high potency of at least 400 C, maintained in an aqueous medium and topically applied to a bodily surface for an extended period of time to render therapeutic treatment.
    Type: Application
    Filed: August 28, 2009
    Publication date: June 9, 2011
    Inventor: Nancy Josephine Polich
  • Patent number: 7923037
    Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: April 12, 2011
    Assignee: Ikaria, Inc.
    Inventors: Kevin J. Tomaselli, Paul A. Hill, Thomas L. Deckwerth, Edward Wintner, Csaba Szabo
  • Patent number: 7858124
    Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: December 28, 2010
    Assignee: Well-Being Biochemical Corp.
    Inventors: Jih Ru Hwu, Shwu Chen Tsay
  • Publication number: 20100310679
    Abstract: The present invention relates to improved compositions for controlling marine pest anemones, to methods of application of same, and to kits for the convenient dispensing of such compositions.
    Type: Application
    Filed: December 31, 2008
    Publication date: December 9, 2010
    Inventor: Sharon Ram
  • Publication number: 20100260733
    Abstract: The present invention discloses novel mechanisms in the aging process and describes novel methods for high-throughput screening to identify, detect, and purify agents to be used for improving mitochondrial function, maintaining the cell cycle-arrested state in senescent and post mitotic cells, and thus preventing or treating age-related diseases or disorders associated with accelerated mitochondrial function loss, telomere dysfunction, and/or deterioration of the growth-arrested state. The present invention also discloses a number of compounds or compositions identified from this method. The present invention further provides the use of low doses of rapamycin or its analogs as a mimic of caloric restriction in preventing age-related diseases or disorders.
    Type: Application
    Filed: April 12, 2010
    Publication date: October 14, 2010
    Inventor: HAIYAN QI
  • Patent number: 7767226
    Abstract: The present invention provides a method for facilitating repair of an area of bone by providing hemihydrate calcium sulfate particles, mixing the particles with an aqueous solution to obtain a paste, applying the paste to an area of bone in need of repair, and allowing the paste to set.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: August 3, 2010
    Assignee: The Research Foundation of State University of New York
    Inventors: YoungBum Park, Rosemary Dziak, Robert J. Genco, Mark Swihart, Hiran Perinpanayagam
  • Patent number: 7754246
    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a ?-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: July 13, 2010
    Assignee: Wright Medical Technology, Inc.
    Inventors: Jon P. Moseley, Michael E. Carroll, Jonathan D. McCanless