Abstract: The two carbohydrate mixture of this invention utilizes a source of fructose in combination with at least one readily digestible glucose polymer source. The addition of the fructose significantly decreases the glycemic response when compared to the digestible glucose polymer alone. Additional components may be added to the simple two component carbohydrate mixture to form a carbohydrate system suitable for incorporation into an enteral nutritional. This carbohydrate system optionally incorporates nonabsorbent carbohydrates, dietary fiber and indigestible oligosaccharides. The present invention is also directed to an enteral nutritional which incorporates the two component carbohydrate mixture and less than 37% of calories from fat. Additionally, the invention is directed to a method of delivering nutrients to a person with diabetes by feeding the enteral nutritional.
Type:
Grant
Filed:
March 14, 2000
Date of Patent:
August 10, 2004
Assignee:
Abbott Laboratories
Inventors:
Bryan W. Wolf, Bradley A. Zinker, Keith A. Garleb, Joseph E. Walton
Abstract: Provided is a method of treating or ameliorating a number of indications in an animal, including a human, comprising administering an effective amount of a compound of the formula I or IA,
wherein J is oxygen, sulfur, or N—Rd.
Type:
Grant
Filed:
May 19, 2003
Date of Patent:
August 3, 2004
Assignee:
Alteon, Inc.
Inventors:
Dilip Wagle, Martin Gall, Stanley C. Bell, Edmond J. LaVoie
Abstract: A method of treating laminitis in a horse is disclosed, comprising administering to the horse a naturally chelated trace mineral composition; promoting healthy skin, hair and hoof tissue. A method of reducing dietary intake is also disclosed, comprising administering to a horse in need thereof, effective amounts of a naturally chelated trace mineral composition. A method of preparing the chelated trace mineral composition from ocean seabed rock is further disclosed, as well as the chelated trace mineral composition.
Abstract: A vitamin and mineral supplement regimen for dialysis patients. The regimen comprises first and second formulations. The first formulation contains selenium, and no zinc, and is administered on days of dialysis. The second formulation contains zinc, and no selenium, and is administered on days between dialysis. In addition, the second formulation contains more vitamin C and folic acid than the first formulation.
Abstract: The use of preparations containing selenite or selenate, mixed with a pharmaceutically acceptable or food compatible acid, for the preparation of an agent for the treatment of wounds is described.
Type:
Application
Filed:
February 25, 2004
Publication date:
July 8, 2004
Inventors:
Jaroslaw Lampe, Ursula Mahner-Ehrig, Peter Kossler, Norbert Fuchs
Abstract: The present invention involves a composition for oral ingestion that contains effective amounts of Glucosamine sulfate, Nettle Leaf, Quercetin, curcumin extract/curcuminoids, Selenium, Zinc, Vitamin C (calcium ascorbate) and Grape Seed Extract, as well as other ingredients and healthy filler ingredients. More specifically, this formulated product is a cartilage and joint maintenance and repair formulation. This formulation allows for enhanced function of joints and cartilage to treat and prevent osteoarthritis, rheumatoid arthritis and other joint ailments/diseases.
Abstract: The invention regards production of vitamin-mineral systems intended for prophylaxis and treatment. The technical result consists in minimization of the doses of consumption of vitamins and minerals at satisfaction of the needs of human organism, in operability of systems, in decrease of labor input for their production and in augmentation of the terms of their storage. The nature of invention is that vitamin-mineral system is made from three-five preparative forms of various composition intended for separate taking, thus each of such forms contains compatible from the point of view of assimilation and storage vitamins and minerals.
Abstract: The present invention relates to compositions without added iron and methods for prophylactic nutritional supplementation and therapeutic nutritional supplementation. Specifically, the method involves administering to an individual a composition comprising carotenoids, vitamin E, vitamin D, vitamin C, thiamine, riboflavin, niacin, folic acid, pyridoxine, biotin, pantothenic acid, cobalamin, magnesium, manganese, zinc, selenium, chromium, copper, alpha lipoic acid, and lutein, wherein the composition is free of added iron.
Abstract: A free radical quenching composition is disclosed comprising a liposome containing at least two antioxidants selected from the following group: beta-carotene, vitamin E, vitamin C, glutathione, niacin, and optionally at least one trace metal (Zn, Se, Cr, Cu, Mn). Also disclosed is a method for reducing the undesirable side effects of free radicals in a mammal by administering to a mammal in need of such antioxidants an effective amount of liposomes containing at least two antioxidants.
Abstract: A procedure for the manufacture of contact lenses for eye treatment, eye protection and eye-care wherein the lenses are impregnated with a suitable composition, a composition for the impregnation of a contact lens for the treatment and/or care and/or protection of the eye, and a kit containing such a composition and one or more contact lenses are disclosed herein. A method for the treatment and/or car and/or protection of the eye comprising wearing contact lenses impregnated with a suitable composition and a composition for disinfection and/or conservation of eye care products is also disclosed herein.
Abstract: Compositions and methods for treating eye discomfort and eye disease are provided. The compositions comprise singly or in combination herbals, natural nutritional supplements, minerals and vitamins. Methods of making these compositions are also provided.
Abstract: The efficacy of vitamins and other nutritional agents in treating and preventing various disease states is improved by administering therapeutically effective levels of these agents on a substantially continuous, 24-hour basis. The concentration of lipid peroxides formed by the autoxidation of lipids, and the concentration of oxygen free radicals, are reduced by continuously administering antioxidant agents. The regeneration of nerve tissue is improved by continuously administering at least one pharmaceutically-acceptable B complex vitamin.
Type:
Grant
Filed:
January 30, 1998
Date of Patent:
February 24, 2004
Assignee:
DrugTech Corporation
Inventors:
George N. Paradissis, R. Saul Levinson, Mitchell I. Kirschner, Marc S. Hermelin
Abstract: The invention relates to the use of &agr;-lipoic acid in reduced or oxidized form or derivatives thereof with intact dithiolane structure in the form of enantiomers or pharmaceutically acceptable salts, amides, esters, thioesters, ethers or metabolites for the adjuvant therapy of dementias.
Type:
Application
Filed:
May 20, 2003
Publication date:
February 5, 2004
Inventors:
Klaus Wessel, Gerald Munch, Klaus Hager, Marlene Kenklies, Michael Lobisch, Manfred Peukert, Harald Borbe, Andreas Marahrens
Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
Abstract: The invention relates to a method for improving the cell protection which comprises the administration of a combination of the extracts of the plants Vitis vinifera and Lycopersicon esculentum with the vitamins C, E, beta-carotene and optionally selenium. Said combination can be used in the prevention of phatological conditions related in part to an overproduction of free radicals like aging, arteriosclerosis and cancer.
Abstract: A nutritional composition is described for prevention or treatment of an immune condition. The composition includes at least vitamin E, vitamin C, vitamin B6, folic acid, vitamin B12, copper, zinc, selenium, fructo-oligosaccharides and/or gum acacia, a probiotic lactic acid bacterium. For example, in an embodiment it comprises per 300 g: 150 IU Vitamin E, 120 mg Vitamin C, 2 mg Vitamin B6, 400 ug Folic acid, 3.8 ug Vitamin B12, 1.5 mg Copper, 15 mg Zinc, 100 ug Selenium, 3 g Fructo-oligosaccharides and/or gum acacia, 10E10 cfu ST11 lactobacillus. Also disclosed are a method for making the nutritional composition, a method for manufacturing a functional food or medicament; and a method of prevention or treatment of an immune condition by administering an effective amount of the composition, functional food or medicament.
Type:
Application
Filed:
May 13, 2003
Publication date:
January 8, 2004
Inventors:
Evelyn Spivey-Krobath, Claude Cavadini, Ferdinand Haschke, Veronique Jaussan, Eduardo Schiffrin
Abstract: The invention is directed to dietary supplements including a core of lysine and bromelain and, optionally, including lycopene. Supplements can further include at least one of Vitamin C, Vitamin E, Vitamin B12, CoEnzymeQ10, lycopene, folic acid, selenium, lecithin and quercetin. Supplements can also further include lutein or xanthin. A preferred supplement includes 5000 mg lysine, 125 mg bromelain, 250 mg Vitamin C,800 IU Vitamin E, 500 mcg Vitamin B 12, 200 mg CoEnzymeQ10, 10 mg lycopene, 800 mcg folic acid, 100 mcg selenium, 250 mg quercetin and 2400 mg lecithin. The supplements have dietary uses or can be used to alleviate dementia-related symptoms.
Abstract: The invention provides a composition and method for the prevention or treatment of mammalian prostate carcinoma using Vitamin E or Vitamin E derivatives or Vitamin E analogs and selenium or selenium salt or selenium derivatives in a combined or an uncombined form, alone or in combination with traditional therapies. The invention also provides a composition and method for the prevention or treatment of mammalian prostate carcinoma using Vitamin E or Vitamin E derivatives or Vitamin E analogs and selenium or selenium salt or selenium derivatives in a combined or an uncombined form, alone or in combination with traditional therapies to increase the levels of intracellular p21 and/or p27.
Abstract: Nutritional compositions containing selenium, colostrum and whey are described. The compositions may be mixed with mammalian food to increase the concentration of glutathione in the mammalian body thereby to enhance the response of the mammal's immune system to infection.
Abstract: Stable water-soluble salts of petroselinic acid with dextran useful as active constituents in pharmaceutical as well as cosmeceutical applications are described.
Abstract: A method and kit for enhancing the natural fertility process. The kit includes a vaginal douche that is used prior to intercourse to enhance the sperm transportation and sustaining properties of the cervical mucous. The douche contains a balanced electrolyte solution, polysaccharides, and pH buffers. The kit also includes nutriceuticals specifically formulated for both the male and female which include amino acids, minerals, vitamins, herbs, phytoestrogens, and antioxidants along with a specified dosing regimen. A basal body temperature thermometer and chart is provided with instructions to confirm when and if ovulation will/did occur. Commercially available urinary chemical reagent strips are provided with instructions so as to predict/confirm if and when ovulation will occur. A lubricating medium will also be provided and utilized at the time of intercourse which is nonspermicidal and which contains polysaccharides which influence natural sperm motility.
Abstract: This invention relates to a method and compositions for the treatment and prevention of disorders associated with endothelial dysfunction consisting of anti-inflammatory agents and dietary supplements.
Abstract: A bioadhesive phosphomatrix composition and method for rapid delivery of effective amounts of active substances through the nasal membrane into the circulatory system. The composition may contain permeation enhancers that facilitate delivery of the active substance to the systemic circulation.
Abstract: A composition and method are provided for substantially preventing hangovers. The composition includes an effective amount of amino acids glycine and Glutathione, B vitamins and at least one mineral compound including each of magnesium, selenium, and molybdenum. Other vitamins, mineral compounds, flavorings, coloring, and solubility agents may also be added.
Abstract: The immune system of middle aged and elderly individuals is stimulated with a dietary supplement. The dietary supplement includes Vitamin E, Vitamin B6 and conjugated linoleic acid. The dietary supplement can further include glutathione alone or in combination with Vitamin C, folic acid, zinc, selenium, Vitamin D, copper and Vitamin B12. The dietary supplement is administered to middle aged and elderly individuals in a suitable form for consumption by the individual. Suitable forms of consumption can include a snack bar, tablet, capsule, powder, drink, or dairy products.
Abstract: Solutions and aerosols of metal-containing compounds are disclosed. Methods of preparing and using the solutions and aerosols, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
Type:
Application
Filed:
February 12, 2003
Publication date:
October 30, 2003
Inventors:
Robert E. Burrell, Scott H. Gillis, Paul Schechter, John B. Wright, Kan Lam, Hua Qing Yin, Antony G. Naylor, Peter H. Moxham
Abstract: A method of preparing a trace element solution includes the steps of providing at least one EDTA-complex, providing a sodium selenite solution, and combining the EDTA-complex(es) and the sodium selenite solution to form a trace element solution. An EDTA complex is prepared by using disodium EDTA or EDTA acid, selenium, and any other suitable mineral.
Type:
Grant
Filed:
August 24, 2001
Date of Patent:
October 28, 2003
Assignee:
Warburton Technology Limited
Inventors:
Robert Naylor Laurie, Lambertus Petrus Vosloos
Abstract: A method of treating onychomycosis is described which includes administration of a topical formulation containing an effective amount of urea and an antioxidant to an infected area around a nail of a patient.
Type:
Application
Filed:
April 22, 2002
Publication date:
October 23, 2003
Applicant:
Bradley Pharmaceuticals, Inc.
Inventors:
Bradley P. Glassman, Dileep Bhagwat, Daniel Glassman
Abstract: A composition of selenium monobromide-oil reaction product including a reaction product of selenium momobromide-in-oil prepared from eleostearic acid and selenium monobromide, which contains at least about 0.1 percent of selenium monobromide and exhibits ultraviolet absorption maxima typical of conjugated trienes and conjugated dienes and pharmnaceutical composition thereof for administration to a subject in a therapeutically effective amount to treat neoplastic conditions such as cancer. Methods of making such compositions are also encompassed, as are methods for treating neoplastic conditions by administering to a subject an effective amount of a selenium monobromide-oil reaction product with epichlorohydrin.
Abstract: The present invention relates to a preparation for stimulating or enhancing an immune system comprising one or more agents that stimulate T-lymphocytes in vivo. Such a preparation can be sued in the prophylaxis and/or treatment of a medical condition. The invention further relates to a preparation for use in a pharmaceutical or food product and to a preparation for medical use.
Type:
Grant
Filed:
December 11, 2000
Date of Patent:
October 14, 2003
Assignee:
Nutricia N.V.
Inventors:
Yvo Maria Franciscus Graus, Hobbe Friso Smit, Albertus Dominicus Marcellinus Erasmus Osterhaus, Robert Johan Joseph Hageman
Abstract: Disinfectant formulations are described which are preferably ecologically friendly and non-toxic to mammals and plants, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains complexes having at least one metal ion which is microbicidal to at least one microorganism and potassium sodium tartrate in some form. When potassium sodium tartrate is used with these metal ions, it enhances the complex-forming properties of such metal complexes while concurrently increases their efficacy and potency at the same level of metal ion concentrations. These microbicidal formulations can be diluted in suitable proportions into aqueous systems to produce the desired dosages for each individual case, depending on the level and the severity of the contamination. The microbicidal formulations can be applied by conventional methods, e.g., spraying, soaking, fogging, impregnation, and the like.
Abstract: A dietary supplement is created, comprised of material from the following nutrients, vitamins, herbs, minerals, and food and plant substances and food and plant derivatives: lycopene, vitamin E, selenium, green tea, coenzyme Q10, garlic, folic acid, vitamin C, curcumin, seaweed, Cordyceps sinsensis mushroom, Lentinus edodes (shiitake) mushroom, and Ganoderma lucidum (reishi) mushroom. The composition is administered orally for individuals who wish to reduce their risk of disease, particularly cancer-risk.
Abstract: Chemical formulations and methods for reducing muscle and joint soreness are disclosed. A representative chemical formulation includes compounds such as a selenium-compound, chondroitin sulfate, glucosamine, and/or methylsulfonylmethane. A representative method for reducing muscle and joint soreness includes administering the chemical formulation to a host.
Abstract: The invention relates to a method for improving the cell protection which comprises the administration of a combination of the extracts of the plants Vitis vinifera and Lycopersicon esculentum with the vitamins C, E, beta-carotene and optionally selenium. The combination can be used in the treatment prevention of pathological conditions related in part to an overproduction of free radicals like aging, arteriosclerosis and cancer.
Abstract: The invention relates to the use as a sebum regulating agent of a hydrolysed vegetable protein produced by enzymatic hydrolysis, and to compositions comprising a hydrolysed vegetable protein produced by enzymatic hydrolysis for application to the skin to inhibit or regulate sebum production, to inhibit or treat oily skin, or to prevent, inhibit or treat acne. The vegetable protein may be for example a cereal protein such as soy protein, wheat protein or an extract from a tree such as cedar, poplar or mimosa, or from the foliage or from the various stages of the flower, such as the bud. Preferably the vegetable protein has a molecular weight in the region of 100,000 to 500,000 Daltons.
Type:
Application
Filed:
January 10, 2003
Publication date:
September 25, 2003
Inventors:
Alain V. Khaiat, Anna Gomes, Vaishali Bhide
Abstract: There is disclosed a method for increasing the antioxidant potential of selenium-containing aqueous solutions, wherein a selenium-containing aqueous solution is supplemented with pharmaceutically acceptable or food-compatible acids, selenium-containing preparations as well as the use of such preparations.
Type:
Application
Filed:
May 14, 2003
Publication date:
September 25, 2003
Inventors:
Peter Kossler, Norbert Fuchs, Bodo Kuklinski, Raimund Schiefer
Abstract: The present invention relates to compositions and methods for the protection and restoration of hearing. In particular, the present invention relates to methods and compositions for the prevention of chemical (e.g., cisplatin) induced deafness. The present invention thus provides methods of improving the outcome of subjects treated with cisplatin.
Type:
Application
Filed:
January 16, 2003
Publication date:
September 25, 2003
Applicant:
The Regents of the University of Michigan
Inventors:
Goran Laurell, Andreas Ekborn, Josef Miller, Hans Ehrsson
Abstract: The treatment of psychiatric or neurological disorders using selenium in combination with drugs used conventionally to treat such disorders is disclosed. The daily dose of selenium is between 10 &mgr;g and 2000 &mgr;g per day.
Abstract: A nutrient pharmaceutical formulation composition useful for treating cancer comprising ascorbic acid, L-lysine, L-proline and at least one polyphenol compound selected from the group consisting of epigallocatechin gallate, epicatechin gallate, epigallocatechin, epicatechin, catechin and the use of the composition in treating cancer and other tumors are provided. A nutrient pharmaceutical formulation composition of EPICAN FORTE™ and its method of use in treating cancer are also disclosed.
Type:
Application
Filed:
January 13, 2003
Publication date:
September 11, 2003
Inventors:
Shrirang Netke, Aleksandra Niedzwiecki, Matthias Rath
Abstract: A composition and method for treating hepatic steatosis, steatohepatitis, and liver diseases associated with or characterized by these conditions. The composition consists essentially of defined amounts of soluble vitamin E, mixed carotenoids and selenium and in one aspect, can include at least one additional agent for the treatment of these conditions.
Type:
Grant
Filed:
May 17, 2002
Date of Patent:
July 22, 2003
Assignee:
The Regents of The University of Colorado
Abstract: A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bound chromium that prevents or reduces the symptoms. Compositions incorporating niacin-bound chromium and additional compounds also are disclosed that are particularly effective in synergistically preventing or reducing these symptoms.
Type:
Application
Filed:
October 4, 2002
Publication date:
July 17, 2003
Inventors:
Debasis Bagchi, Harry G. Preuss, Shil C. Kothari
Abstract: Nutritional or therapeutic compositions containing glutamic acid, cystine, glycine and a selenium precursor and methods for their utilization to increase glutathione synthesis and thereby enhance the immune system are described.
Abstract: The present invention relates to a composition comprising a catechin compound, ascorbic acid, proline and lysine. The present invention also relates to a method for treating neoplastic disease using a composition comprising a catechin compound, ascorbic acid, proline and lysine.
Type:
Application
Filed:
January 8, 2002
Publication date:
July 10, 2003
Inventors:
Shrirang Netke, Vadim Ivanov, Waheed M. Roomi, Aleksandra Niedzwiecki, Matthias Rath
Abstract: The present invention relates to a composition for suppressing or ameliorating a symptom accompanying diminished homeostasis, comprising theanine; and a mineral composition comprising theanine and a mineral. According to the present invention, there can be provided a composition for suppressing or ameliorating the above symptoms; and a mineral composition having a reduced peculiar metal taste, of which administration is made easily.
Abstract: Nutritional compositions containing selenium, colostrum and whey are described. The compositions may be mixed with mammalian food to increase the concentration of glutathione in the mammalian body thereby to enhance the response of the mammal's immune system to infection.
Abstract: Provided is a nutraceutical composition including a tripeptoid component, a flavonoid component, guanidine hydrochloride, &agr;-lipoic acid, an amino acid component, a brazilin component, catalase, and, optionally, vitamin E ans selenium. The composition is effective to maintain normal blood sugar levels and normal levels of non-enzymatic protein glycosylation in a human.
Type:
Grant
Filed:
November 13, 2001
Date of Patent:
July 1, 2003
Inventors:
Rudolph Cartwright, Leo Edward Hendricks
Abstract: Compositions and methods for reducing cytotoxicity are provided. Compositions and methods for inhibiting angiogenesis are provided. The compositions comprise herbals, natural nutritional supplements, minerals and/or vitamins.
Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among children.