Bicarbonate Patents (Class 424/717)
  • Patent number: 10251953
    Abstract: The present invention relates to a solution for peritoneal dialysis consisting of one or more separate solutions. A treatment free of side-effects with a simultaneous lowering of blood pressure can be achieved in that the solution contains sodium ions in a concentration in the region from 121 to 129 mmol/l, preferably at 125 mmol/l. The invention furthermore relates to a double-chambered pouch having a peritoneal dialysis solution consisting of two separate solutions which consists of a plastic pouch in which a first chamber with the first separate solution and a second chamber with the second separate solution are arranged adjacent to one another, with both chambers being separated from one another by a weld seam dimensioned such that it opens on pressure onto one of the chambers filled with liquid so that the content of the two chambers can be mixed with one another.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: April 9, 2019
    Assignee: Fresenius Medical Deutschland GMBH
    Inventors: Jutta Passlick-Deetjen, Thomas P. Schaub, Georg Topp
  • Patent number: 10138442
    Abstract: An outdoor cleaning concentrate composition having improved dirt and stain cleaning properties on outdoor surfaces, that is less corrosive and capable of being used with a water spraying system; and that is environmentally friendly. The outdoor cleaning concentrate composition includes the following components: a surfactant selected from the group consisting of alkyl glucosides, alkyl carboxylates, alkyl polyoxyethylenes, alkyl polysaccharides, alkylamine ethoxylates, amphoterics, amine oxides, polyalkylene glycol, sarcosines and sarcosinates; a fungicide; a chelating agent; a disinfectant; and a specific pH range. The surfactant is preferably an alkyl glucoside; more preferably, caprylyl/decyl glucoside. The fungicide is preferably potassium bicarbonate, while the disinfectant is preferably potassium carbonate.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: November 27, 2018
    Assignee: Jelmar, LLC
    Inventor: Rosemary A. Gaudreault
  • Patent number: 9895395
    Abstract: A method is provided for attenuating free radical formation resulting from a bodily insult. The method includes administering bicarbonate to the body of a subject at a dosage ranging from 1.5 mEq/kg of body weight to 5.0 mEq/kg of body weight within a 24-hour period.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: February 20, 2018
    Assignee: MD Scientific, LLC
    Inventor: W. Patrick Burgess
  • Patent number: 9821102
    Abstract: The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: November 21, 2017
    Assignee: Gambro Lundia AB
    Inventors: Olof Jansson, Torbjorn Linden, Anders Wieslander
  • Patent number: 9572850
    Abstract: The present invention relates to a combination of cajeput and extract from the plant Pimenta racemosa for use in preventing ornamental fish parasite infestation or removing ornamental fish parasites. The combination of cajeput and extract from the plant Pimenta racemosa is administered to the fish.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: February 21, 2017
    Assignee: Mars, Incorporated
    Inventor: Bettina Schelkle
  • Patent number: 9480251
    Abstract: An environmentally safe, non-phytotoxic pesticidal composition comprising natural plant oils geraniol and cedar oil and methods of controlling insects is provided.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: November 1, 2016
    Assignee: FMC Corporation
    Inventors: James F. Walter, Reid M. Ipser
  • Patent number: 9464111
    Abstract: A short chain polypeptide having antioxidant activity is provided. The short chain polypeptide has 2 to 4 amino acids bonded to form a polypeptide chain having an amine-terminal end and a carboxyl terminal end; wherein a net charge of the short chain polypeptide is positive, the amino terminal amino acid is an amino acid selected from the group consisting of arginine, lysine and histidine, the polypeptide chain following from the amino terminus comprises a hydrophobic or neutral amino acid, and the polypeptide chain is free of an amino acid having a negatively charged side-chain group. A method to prepare a composition having antioxidant activity and a composition having antioxidant activity are also provided.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: October 11, 2016
    Assignee: L'OREAL
    Inventor: Anne Young
  • Patent number: 9456611
    Abstract: There is disclosed a method for treating a plant infection caused by a fungus of the class ascomycetes, comprising applying to the plant a combination of tea tree oil (TTO) and a synthetic fungicidal compound. Other embodiments are also disclosed.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: October 4, 2016
    Assignee: STOCKTON (ISRAEL) LTD.
    Inventor: Moshe Reuveni
  • Patent number: 9084811
    Abstract: The present invention relates to a novel bacterial strain isolated from groundwater. The invention also relates to bacterial extracts and to the use of same in the context of the treatment of inflammations. More particularly, the present invention relates to novel compositions of interest in the treatment and the prevention of inflammatory disorders, notably dermatological pathologies.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: July 21, 2015
    Assignees: PIERRE FABRE DERMO-COSMETIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Philippe Lebaron, Muriel Bourrain, Nathalie Castex-Rizzi, Thien Nguyen
  • Publication number: 20150147374
    Abstract: Parasiticidal aqueous suspension typically comprising from 1 to 15% by weight of silica and from 30 to 45% of alkali metal bicarbonate, and method for controlling the development of parasites on animals reared in buildings, according to which the animal's environment in the building is brought into contact with this aqueous suspension.
    Type: Application
    Filed: January 30, 2015
    Publication date: May 28, 2015
    Inventors: Jean-Philippe PASCAL, Nicolas PALANGIE
  • Publication number: 20150133296
    Abstract: The present invention relates to phytosanitary compositions with fungicidal properties that comprise a mixture of essential oils obtained from plants and agents with known fungicidal properties, such as alkali metal or ammonium bicarbonates, and compounds based on copper or the salts thereof, for use, principally, in contact-protection against fungal infections in cultivated plants and post-harvest, and also in other antifungal applications. In said compositions, the effect of the agents that have known fungicidal properties is potentiated synergistically by the aforementioned essential oils. The present invention also relates to the use of said essential oils as potentiators for agents with known fungicidal properties.
    Type: Application
    Filed: January 5, 2012
    Publication date: May 14, 2015
    Applicant: BIOFUNGITEK, SOCIEDAD LIMITADA
    Inventors: Unai Ona Ugalde Martinez, Ana Belen Rodriguez Urra, Ainara Ubegun Lizaso
  • Publication number: 20150132344
    Abstract: An oral combination therapy or oral composition that protects orally administered exogenous leptin from the environment of the gastrointestinal tract, allowing delivery of the exogenous leptin to the bloodstream. The oral combination therapy includes (a) leptin or a leptin functional derivative; (b) a stomach acid-neutralizing agent such as a buffer; and (c) a pancreatic protease inhibitor that protects the exogenous leptin from degradation by pancreatic enzymes; and (d) a bile acid or a bile acid analog that facilitates absorption of the exogenous leptin. The oral combination therapy or oral composition may also include at least one agent that stimulates endogenous leptin secretion; as well as at least one agent capable of promoting, enhancing or improving adherence to treatment such as a sweetener or a satiety triggering agent.
    Type: Application
    Filed: November 18, 2011
    Publication date: May 14, 2015
    Applicant: UNIVERSITE DE MONTREAL
    Inventors: Moise Bendayan, Philippe Cammisotto
  • Publication number: 20150132404
    Abstract: A feed supplement mixture for performance horses provides a high protein nutritional supply while lowering stress experienced by the horse, reduces the onset of ulcers in the horse's digestive tract and treats ulcers in horses already afflicted with ulcers by the introduction of a quantity of thiamine to reduce stress and sodium bicarbonate to raise the ph level of the feed and the horse's stomach content.
    Type: Application
    Filed: October 30, 2014
    Publication date: May 14, 2015
    Inventor: George Aaron Custer
  • Patent number: 8993599
    Abstract: In one general aspect of the present invention, pharmaceutical formulations comprising both a proton pump inhibitor microencapsulated or dry coated with a material that enhances the shelf-life of the pharmaceutical composition and one or more antacid are described. In another general aspect of the present invention, pharmaceutical formulations comprising both a proton pump inhibitor microencapsulated or dry coated with a taste-masking material and one or more antacid are described.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: March 31, 2015
    Assignee: Santarus, Inc.
    Inventors: Warren Hall, Kay Olmstead, Laura Weston
  • Publication number: 20150086638
    Abstract: Aqueous parasiticidal suspension typically comprising from 1 to 15% by weight of silica and from 30 to 45% by weight of sodium bicarbonate and method for controlling the development of parasites on animals raised in buildings, according to which the environment of the animal in the building is brought into contact with this aqueous suspension.
    Type: Application
    Filed: December 1, 2014
    Publication date: March 26, 2015
    Applicant: SOLVAY SA
    Inventors: Nicolas PALANGIE, Jean-Philippe Pascal
  • Publication number: 20150071979
    Abstract: A sodium bicarbonate product comprises particles containing sodium bicarbonate and an organic material that is a solid at ambient temperature. The particles have a structure comprised of individual crystallites of sodium bicarbonate attached together in the particle. More than 95% by volume of the particles have a size less than 200 ?m. Particles of the product are hollow and are formed of an outer shell of the crystallites. The product may be used, for example, as a leavening agent in the production of cooked foods. The product may be produced by spray drying a solution or slurry dissolved organic material and dissolved sodium bicarbonate. The sodium bicarbonate may be present as a suspension.
    Type: Application
    Filed: February 20, 2013
    Publication date: March 12, 2015
    Inventors: Sarah Gaunt, Stephen John Minter, Edna Elaine Best, Warren L. Nehmer
  • Publication number: 20150056307
    Abstract: The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy.
    Type: Application
    Filed: March 19, 2014
    Publication date: February 26, 2015
    Applicant: BRAINTREE LABORATORIES, INC.
    Inventor: William A. Shaver
  • Patent number: 8956665
    Abstract: Stable aqueous compositions of silane quaternary ammonium compounds are provided by diluting an alkanol solution of the silane quaternary ammonium compound in water with at least one nonionic surfactant. The weight ratio of the silane quaternary ammonium compound and nonionic surfactant is provided to yield a composition which can remain stable in dilute aqueous compositions, can be applied to any surface and dry quickly to provide an anti-microbial film. The addition of an alkali metal bicarbonate salt to the composition improves the anti-microbial properties as well as the drying time of the composition.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: February 17, 2015
    Assignee: Church & Dwight Co., Inc.
    Inventors: Steven A. Bolkan, Christine Stairiker, Melvin H. Czechowski, Mark Ventura
  • Publication number: 20150044303
    Abstract: The present invention relates to pharmaceutical formulations comprising at least one acid-labile proton pump inhibiting agent and at least one antacid, which have improved bioavailability, chemical stability, physical stability, dissolution profiles, disintegration times, safety, as well as other improved pharmacokinetic, pharmacodynamic, chemical and/or physical properties. The present invention is directed to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a gastrointestinal disorder or disease, or the symptoms associated with, or related to, a gastrointestinal disorder or disease in a subject in need thereof.
    Type: Application
    Filed: August 25, 2014
    Publication date: February 12, 2015
    Inventors: Kay Olmstead, Warren Hall, Gerald T. Proehl
  • Publication number: 20150010654
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Application
    Filed: July 29, 2014
    Publication date: January 8, 2015
    Inventors: Roland R. Arnold, David C. Henke
  • Publication number: 20140377376
    Abstract: The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
    Type: Application
    Filed: June 11, 2012
    Publication date: December 25, 2014
    Applicant: Gambro Lundia AB
    Inventors: Olof Jansson, Torbjorn Linden, Anders Wieslander
  • Publication number: 20140348955
    Abstract: Disclosed are methods of reducing the risk that a medical treatment comprising inhalation of nitric oxide gas will induce an increase in pulmonary capillary wedge pressure in pediatric patients, leading to pulmonary edema. The methods include avoiding or discontinuing administration of inhaled nitric oxide to a pediatric patient determined to have pre-existing left ventricular dysfunction but who otherwise is a candidate for inhaled nitric oxide treatment (e.g., for pulmonary hypertension), and administering inhaled nitric oxide to pediatric patients who are candidates for such treatment and who are determined not to have pre-existing left ventricular dysfunction.
    Type: Application
    Filed: August 7, 2014
    Publication date: November 27, 2014
    Applicant: INO THERAPEUTICS LLC
    Inventor: James S. Baldassarre
  • Publication number: 20140341963
    Abstract: A composition comprising at least one substance coated with an agent wherein the agent forms a liquid impermeable but gas permeable layer surrounding the said substance and preventing the passage of the said substance through said coating, wherein in-use the said substance is not released into solution in the body, and wherein said substance is selected from one or more of the group consisting of calcium phosphate, sodium chloride, potassium chloride, magnesium chloride, calcium carbonate, and sodium bicarbonate for use in the treatment of osteoporosis and other bone conditions.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 20, 2014
    Applicant: ActiveSignal Holding Limited
    Inventor: Ward Warren
  • Publication number: 20140338665
    Abstract: Disclosed are methods of reducing the risk that a medical treatment comprising inhalation of nitric oxide gas will induce an increase in pulmonary capillary wedge pressure in pediatric patients, leading to pulmonary edema. The methods include avoiding or discontinuing administration of inhaled nitric oxide to a pediatric patient determined to have pre-existing left ventricular dysfunction but who otherwise is a candidate for inhaled nitric oxide treatment (e.g., for pulmonary hypertension), and administering inhaled nitric oxide to pediatric patients who are candidates for such treatment and who are determined not to have pre-existing left ventricular dysfunction.
    Type: Application
    Filed: August 4, 2014
    Publication date: November 20, 2014
    Applicant: INO Therapeutics LLC
    Inventor: James S. Baldassarre
  • Patent number: 8883762
    Abstract: The present invention provides a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. Glucose-like degradation and hydrolysis is avoided during sterilization and storage, while maintenance of a neutral mixture pH is achieved by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further discloses a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: November 11, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Thomas Zimmeck
  • Publication number: 20140271933
    Abstract: The present invention relates to a method of consuming a universal potent healing tonic. When consumed according to the method, of a host of medical ailments can be abated including cancer, arthritis, and insomnia.
    Type: Application
    Filed: July 23, 2013
    Publication date: September 18, 2014
    Inventor: Nathaniel Cooper
  • Publication number: 20140271932
    Abstract: A rodenticidal composition comprising a carbon dioxide release agent and a carrier may be disclosed. A method of controlling rodents at a locus by applying the composition of the disclosure may be disclosed.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Inventors: Phyllis Rubel, Sidney Goldman, Bogdan Enache
  • Publication number: 20140271853
    Abstract: The present invention relates to combinations of a proton pump inhibiting agent and at least one buffering agent that have been found to possess improved bioavailability, chemical stability, physical stability, dissolution profiles, disintegration times, as well as other improved pharmacokinetic, pharmacodynamic, chemical and/or physical properties.
    Type: Application
    Filed: May 29, 2014
    Publication date: September 18, 2014
    Applicant: SANTARUS, INC.
    Inventors: Warren Hall, Laura Weston, Kay Olmstead, Laura Gallo, Craig Bowe
  • Patent number: 8828232
    Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: September 9, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Dilip H. Shah, Todd Ing
  • Patent number: 8828452
    Abstract: Methods for providing post-operative pain control or relief to a patient are disclosed. Methods include, for example, administering bicarbonate to an area of a patient during a surgical or dental procedure, near completion of a surgical or dental procedure or immediately following a surgical or dental procedure, in an area previously administered or containing a regional or local anesthetic in an amount sufficient to provide the patient with pain control or relief for a period of time after the surgical or dental procedure.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: September 9, 2014
    Inventor: Glenn Abrahmsohn
  • Patent number: 8815916
    Abstract: The present invention relates to pharmaceutical formulations comprising at least one acid-labile proton pump inhibiting agent and at least one antacid, which have improved bioavailability, chemical stability, physical stability, dissolution profiles, disintegration times, safety, as well as other improved pharmacokinetic, pharmacodynamic, chemical and/or physical properties. The present invention is directed to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a gastrointestinal disorder or disease, or the symptoms associated with, or related to, a gastrointestinal disorder or disease in a subject in need thereof.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: August 26, 2014
    Assignee: Santarus, Inc.
    Inventors: Kay Olmstead, Warren Hall, Gerald T. Proehl
  • Patent number: 8815303
    Abstract: Particular aspects provide novel insecticide/miticide/fungicide compositions, and methods for using same for safe, environmentally friendly control of insects, mites and fungal pests in, e.g., gardening and commercial growing. Preferably, the compositions comprise organic or pure ingredients. Particular embodiments comprise: a fatty acid soap base (e.g., saponified soap with retained glycerin; or fatty acid salts with glycerin); at least one essential oil; an optional food oil; and a bicarbonate reagent, along with water. Additional embodiments comprise: a soap base, and/or glycerin or other suitable base; at least one organic or pure plant essential oil; an organic or pure food oil; and a bicarbonate reagent, along with water as diluent and carrier, and methods for using same. Further aspects provide a method for controlling mite and fungal pests with a single composition comprising, along with an aqueous carrier or diluent: a non-petroleum-based food oil; and a bicarbonate agent.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: August 26, 2014
    Inventor: Susan E. Lewis
  • Patent number: 8790714
    Abstract: The present invention is in the fields of medicine, pharmaceuticals, neutraceuticals and rheumatology. In one aspect, the invention provides pharmaceutical compositions for the treatment and/or prevention of osteoarthritis in mammals, particularly humans, comprising sodium bicarbonate and calcium gluconate, and optionally comprising one or more additional components. The invention also provides methods of treating or preventing osteoarthritis by administering to a mammal, preferably via intraarticular injection, one or more compositions of the invention.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: July 29, 2014
    Assignee: Nucitec, S.A. de C.V.
    Inventors: Ricardo Amador, Jorge L. Rosado, Sandra García-Padilla, Miguel Ángel Duarte-Vázquez
  • Publication number: 20140199416
    Abstract: A solution having improved mold and mildew stain removing properties on hard surfaces, that is easier to handle (less corrosive and less malodorous) and that is environmentally friendly. The mold and mildew stain removing solution includes the following components: a surfactant selected from the group consisting of alcohol ethoxylates, alkyl sulfates, alkyl ether sulfates, alpha olefin sulfonates, alkyl phosphates, alkyl amidopropyl betaines, alkyl betaines, amphoacetates, amphoproprionates, amphosulfonates, amine oxides, alkanolamides, sulfosuccinates, and sultaines, a solvent, and at least one chelating agent. The solution may further comprise a hydrotrope, a diluent, a preservative, and/or a fungicide. The surfactant is preferably an alcohol ethoxylate. The hydrotrope is preferably lauramine oxide. The solvent is preferably a glycol ether. The chelating agents are preferably sodium gluconate and a solution of the trisodium salt of methyl glycine diacetic acid.
    Type: Application
    Filed: January 16, 2013
    Publication date: July 17, 2014
    Applicant: Jelmar, LLC.
    Inventor: Rosemary Gaudreault
  • Patent number: 8778311
    Abstract: The present invention relates to an oral composition comprising, in an orally acceptable carrier, from about 0.1% to about 5% zinc oxide; and from about 0.1% to about 5% of a source of carbonate ions selected from alkali metal and ammonium carbonates and bicarbonates. The molar ratio of carbonate ion to zinc ion is from about 0.05:1 to about 1:1. The composition has good antiplaque efficacy and taste. Preferred compositions are toothpastes.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: July 15, 2014
    Assignee: The Procter & Gamble Company
    Inventors: Meinrad Regner, Maurice Joseph Prendergast, Owen Thurlby
  • Publication number: 20140166028
    Abstract: A method for the administration of nicotine, THC, tobacco, cannabidiol or a base alkaloid includes administering in the oral or nasal cavity an absorption conditioning unit having at least two agents selected from the group consisting of (a) a buffer agent, (b) a capturing agent, (c) a penetration agent, and (d) a thermal agent, to the mammal, and then administering by inhalation a bioactive agent selected from the group consisting of nicotine, THC, cannabidiol and a base alkaloid. The absorption conditioning unit may be in a dosage form not containing a drug. The absorption conditioning unit may create a pH in the oral cavity or nasal cavity of 7.8-10 for a period of ten minutes or more after administration, the dosage form not containing an acid and not containing a drug.
    Type: Application
    Filed: April 26, 2013
    Publication date: June 19, 2014
    Inventors: Richard C. FUISZ, Joseph M. FUISZ
  • Patent number: 8753618
    Abstract: The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: June 17, 2014
    Assignee: Braintree Laboratories, Inc.
    Inventor: William A. Shaver
  • Patent number: 8747912
    Abstract: A drug delivery system for the controlled release of a pharmaceutically-active compound by oral route comprises an intercalate of a layered double hydroxide having, before intercalation, layers of metal hydroxides, and having intercalated therein a pharmaceutically-active compound having at least one anionic group. A preferred layered double hydroxide is one that has layers which comprise [LiAl2(OH)6]+. The drug delivery system has use in the delivery of drugs such as 4-biphenylacetic acid, Diclofenac, Gemfibrozil, Ibuprofen, Naproxen, 2-Propylpentanoic acid and Tolfenamic acid.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: June 10, 2014
    Assignee: Isis Innovation Limited
    Inventor: Dermot Michael O'Hare
  • Patent number: 8728540
    Abstract: Textiles coated with aqueous compositions of silane quaternary ammonium compounds and alkali metal bicarbonates are provided with deodorization properties and protection from allergens, irritants, molds, dust mites, bacteria, and fungi.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: May 20, 2014
    Assignee: Church & Dwight Co., Inc.
    Inventors: Steven Bolkan, Christine Beneciuk, Melvin H. Czechowski, Mark Ventura, David Stott, Nicole Nguyen, Steven T. Adamy
  • Publication number: 20140134251
    Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.
    Type: Application
    Filed: October 23, 2013
    Publication date: May 15, 2014
    Applicant: PULMATRIX, INC.
    Inventors: Michael M. LIPP, Robert W. CLARKE, David L. HAVA, Richard BATYCKY, John HANRAHAN
  • Patent number: 8709500
    Abstract: A drug delivery system for the controlled release of a pharmaceutically-active compound by oral route comprises an intercalate of a layered double hydroxide having, before intercalation, layers of metal hydroxides, and having intercalated therein a pharmaceutically-active compound having at least one anionic group. A preferred layered double hydroxide is one that has layers which comprise [LiAl2(OH)6]+. The drug delivery system has use in the delivery of drugs such as 4-biphenylacetic acid, Diclofenac, Gemfibrozil, Ibuprofen, Naproxen, 2-Propylpentanoic acid and Tolfenamic acid.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: April 29, 2014
    Assignee: Isis Innovation Limited
    Inventor: Dermot Michael O'Hare
  • Patent number: 8709396
    Abstract: The invention is a method for attracting mosquitoes by producing a volatilized acid by combining an acid precursor with water to produce the humidified vapor acid attractant, preferably hydrogen chloride. The humidified volatilized acid can be further combined with carbon dioxide, or carbon dioxide can be simultaneously produced to attract mosquitoes. The acid precursor can be a hydrate of ferric chloride, such as ferric chloride hexahydrate. The acid precursor can be impregnated in a carrier, and can be combined with water through exposure to water vapor in the atmosphere, the intentional addition of water, or water produced by a chemical reaction.
    Type: Grant
    Filed: February 18, 2008
    Date of Patent: April 29, 2014
    Assignee: Premark FEG L.L.C.
    Inventors: Joel Tenney, Tom Isaac, William Ernst
  • Publication number: 20140113009
    Abstract: According to aspects of the present disclosure, a kit for transepithelial delivery of a cross-linking agent to a cornea includes a first vessel containing an initial formulation that includes a cross-linking agent and a first active ingredient configured to open corneal epithelial tight junctions when applied to a cornea and one or more second vessels each containing a respective secondary formulation that includes the cross-linking agent for application to the cornea after the initial formulation is applied to the cornea.
    Type: Application
    Filed: October 24, 2013
    Publication date: April 24, 2014
    Applicant: Avedro, Inc.
    Inventors: David Muller, Stephen M. Blinn, Robert Broderick
  • Patent number: 8685473
    Abstract: There is provided a process for making a composition suitable for topical application comprising the steps of a) heating at least one fruit and/or vegetable pulp to up to a temperature in the range of about 40° C. to 100° C.; b) mixing between 1 and 40% w/w of a mild base with the heated fruit and/or vegetable pulp. There is also provided a fruit and/or vegetable derived composition suitable for topical application prepared by the above process. There is further provided a fruit and/or vegetable derived composition comprising at least one fruit and/or vegetable derived pulp and a mild base, said composition having a pH in the range of about 7.5 to about 9.5.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: April 1, 2014
    Assignee: Phoenix Eagle Company Pty. Ltd.
    Inventor: Thomas James McArthur
  • Patent number: 8597691
    Abstract: An anti-hypothermia composition is provided, in particular an anti-hypothermia composition that prevents hypothermia caused by general anesthesia during surgical operations. The composition prevents hypothermia by preventing the decrease in the biological function of patients and correcting acidosis. Specifically, the anti-hypothermia composition is a preparation containing a bicarbonate ion and provided in the form of an infusion fluid. The infusion fluid preferably contains sodium bicarbonate as a major component that serves as a source of the bicarbonate ion, along with each or a combination of other electrolytes, glucose and amino acids.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: December 3, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kazunori Satou, Takashi Ogawa, Saori Mori
  • Patent number: 8597690
    Abstract: A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising 1.5 parts by weight powdered fennel, 2.0 parts by weight powdered rhubarb, 1.0 part by weight powdered glycyrrhiza, 2.0 parts by weight powdered phellodendron bark, 1.0 part by weight powdered zedoary, 1.5 parts by weight powdered picrasma wood, 1.0 part by weight powdered matricaria chamomilla, 1.5 parts by weight powdered geranium herb, 1.0 part by weight powdered ginseng, 1.5 parts by weight powdered citrus unshiu peel, 1.0 part by weight powdered scutellaria root, 1.0 part by weight powdered magnolia bark, 2.0 parts by weight powdered oyster shell, 1.0 part by weight powdered cyperus rhizome, 2.0 parts by weight powdered platycodon root, 2.0 parts by weight powdered melia azedarach, 1.0 part by weight powdered cnidium rhizome, 2.0 parts by weight sodium bicarbonate and 4.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: December 3, 2013
    Assignee: Nakamori Pharmaceutical Co., Ltd.
    Inventor: Toshio Nakamori
  • Publication number: 20130302438
    Abstract: A process for producing aqueous chlorous acid solution in which chlorous acid, which is safe for the human body, is easy to handle, and less generates chlorine dioxide, is yielded and used as a disinfectant for a pretreatment in food processing. To an aqueous sodium chlorate solution is added sulfuric acid or an aqueous solution thereof in such an amount and concentration that the pH of the aqueous solution can be kept at 2.3-3.4 to thereby react them and generate chloric acid. Subsequently, hydrogen peroxide is added to the chloric acid in an amount which is equal to or larger than the amount necessary for a reduction reaction to thereby yield chlorous acid. Any one of inorganic acids, inorganic acid salts, organic acids, and organic acid salts, or two or more thereof, or a combination or these is added to the aqueous solution containing chlorous acid yielded, whereby the chlorous and acid can be present for long and the pH of the aqueous solution is regulated to regulated to 3.2-7.0.
    Type: Application
    Filed: April 15, 2013
    Publication date: November 14, 2013
    Inventor: Hisataka Goda
  • Publication number: 20130303976
    Abstract: A method for preventing mesothelial cell trauma is described. The method comprises applying at pool of conditioning techniques prior and/or during surgery for decreasing detrimental factors and optimally using beneficial factors. The pool of conditioning techniques thereby comprises at least applying an irrigation liquid to irrigate at least part of the area of surgery wherein the irrigation liquid is a pH buffering liquid.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 14, 2013
    Inventors: Karina MAILOVA, Leila ADAMYAN
  • Publication number: 20130287867
    Abstract: The invention relates to a composition for use in the very rapid treatment of cell degeneration, in particular in oncologic field, characterized in that it is constituted by a compound of Potassium Bicarbonate and D-Ribose.
    Type: Application
    Filed: December 9, 2011
    Publication date: October 31, 2013
    Inventor: Eliseo Garuti
  • Publication number: 20130287866
    Abstract: Use of nitric oxide amino acid esters for improving vascular circulation, and prophylaxis or treatment of a condition associated with impaired blood circulation, such as peripheral vascular disease. The nitric oxide amino acid esters may be co-administered with an antimicrobial in topical or transdermal compositions for improving vascular circulation, and prophylaxis or treatment of a condition associated with impaired blood circulation.
    Type: Application
    Filed: October 26, 2011
    Publication date: October 31, 2013
    Applicant: ORAL DELIVERY TECHNOLOGY LTD.
    Inventor: Michael Farber