Bicarbonate Patents (Class 424/717)
  • Patent number: 5124144
    Abstract: The invention provides an orally administered pharmaceutical composition for use in gastrointestinal washes, particularly for diagnostic use, or as a cathartic laxative, of the type containing polyethyleneglycol, anhydrous sodium sulphate, sodium bicarbonate, sodium chloride and potassium chloride, characterized by also containing the following components: saccharin, acesulfame-K and a flavoring chosen from the following: mandarin, fresh fruit flavoring.
    Type: Grant
    Filed: April 11, 1990
    Date of Patent: June 23, 1992
    Assignee: Giuliani S.p.A.
    Inventors: Enzo Giorgetti, Virginio Castagnola, deceased, Giuliano Frigerio
  • Patent number: 5112622
    Abstract: Disclosed is a novel therapy involving infusion of specially adapted electrolyte solution comprising essentially physiological concentrations of sodium and other cations and in general higher than physiological concentrations of bicarbonate. The therapy is related to treatment of altered renal function and prophylactic treatment of a patient to resist onset of altered renal function.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: May 12, 1992
    Inventor: Klaus F. Kopp
  • Patent number: 5100674
    Abstract: Preparation of an effervescent aqueous solution which has an emollient action on the cuticles of the nails, by dissolving the following anhydrous solid compounds substantially simultaneously in water: urea, pyrrolidonecarboxylic acid and an alkali metal and/or ammonium bicarbonate, and additional ingredients, the different compounds being introduced in the form of a mixture or of several separate mixtures prepared in advance. These mixtures are in pulverulent or tablet form.Composition for the preparation of the effervescent aqueous solution.Cosmetic treatment of the cuticle of the nails using the effervescent aqueous solution.
    Type: Grant
    Filed: October 5, 1990
    Date of Patent: March 31, 1992
    Assignee: L'Oreal
    Inventors: Jean-Claude Ser, Florence Martin
  • Patent number: 5087442
    Abstract: There is described a preparation for iron supply comprising, as essential ingredients, a prescribed iron containing compound, sodium carbonate or sodium hydrogencarbonate and a neutralizing agent. This preparation is easily dissolved in water, and has a good taste so that it is agreeable to drinking, whereby a sufficient amount of iron can be suitably supplied to the living body. Also, there is described a preparation for iron supply or vitamin supply, to which potassium carbonate is added as a preservation stabilizing agent.
    Type: Grant
    Filed: October 4, 1989
    Date of Patent: February 11, 1992
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Akihisa Takaichi, Toshihiko Okamoto, Toshiaki Matsumoto
  • Patent number: 5085853
    Abstract: An oral composition is provided having a first peroxide-containing component and a second bicarbonate-containing component. The first component has a flavor which is reactively incompatible with bicarbonate salts while the second component has a flavor which is reactively compatible with the bicarbonate.
    Type: Grant
    Filed: June 24, 1991
    Date of Patent: February 4, 1992
    Assignee: Chesebrough-Pond's U.S.A., division of Conopco, Inc.
    Inventors: David R. Williams, Christine W. Ryles
  • Patent number: 5045324
    Abstract: The invention provides a pasty composition for perfusing artificial kidney systems for dialysis, the composition comprising about 30 to about 70% by weight of solid electrolyte components consisting of NaCl, KCl, CaCl.sub.2, MgCl.sub.2 and CH.sub.3 COONa and about 70 to about 30% by weight of water, and the composition having a viscosity of about 1,000 to about 7,000 cps at 25.degree. C., and also provides a process for preparing a pasty composition for perfusing artificial kidney systems for dialysis, the process comprising the steps of uniformly mixing NaCl, KCl, CaCl.sub.2, MgCl.sub.2 and CH.sub.3 COONa, adding water and finely dividing the mixture.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: September 3, 1991
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventor: Hisao Mukai
  • Patent number: 5037648
    Abstract: A skin conditioning composition in the form of a lotion applied to the skin has bicarbonate ions in an emollient carrier and pH in excess of 7.0. The composition is formed by the combining of a diluent with thickener/stabilizer and a hemectant with a fat agent and emulsifier which brings the pH to 7.0 and above 7.0 to which is added an aqueous solution of sodium bicarbonate. A quantity of mineral oil which serves as an emollient is a preferred addition to the final mixture.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: August 6, 1991
    Inventor: Evelyn S. Joiner
  • Patent number: 5037657
    Abstract: The rate of disintegration and/or dissolution of effervescent acetylsalicylic acid tablets obtained by direct compression of a dry powder mixture is surprisingly increased by incorporating in said mixture powdered dextrose and/or sucrose. Preferably, spray-crystallized dextrose is used.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: August 6, 1991
    Assignee: Nicholas Kiwi Pty Limited
    Inventors: Stephen K. Jones, Peter D. Wilson
  • Patent number: 5034416
    Abstract: A pharmaceutically acceptable composition comprising Diflunisal and Naproxen or its salt in combination with a bicarbonate or carbonate.
    Type: Grant
    Filed: February 1, 1990
    Date of Patent: July 23, 1991
    Inventor: Walton J. Smith
  • Patent number: 5028437
    Abstract: A veterinary composition useful for treatment of energy depletion, dehydration and electrolyte imbalance in diarrhoeic neonatal animals consisting essentially of(a) glucose in an amount sufficient to produce a concentration level of from greater than 200 nM to 250 mM when in an aqueous solution,(b) one or more sodium salts in an amount sufficient to produce a sodium ion concentration level of from 60 mM to 120 mM when in an aqueous solution, and(c) one or more chloride salts in an amount sufficient to produce a chloride ion concentration level of 50 mM to 90 mM when in an aqueous solution.
    Type: Grant
    Filed: August 21, 1989
    Date of Patent: July 2, 1991
    Assignee: The State of Victoria
    Inventor: Ian V. Jerrett
  • Patent number: 4975286
    Abstract: An aqueous cathartic solution and method for bowel cleansing is provided. The solution is isotonic, has a minimum buffering effect on human blood and is substantially inorganic. The aqueous solution includes about 3.5 grams/liter of sodium sulfate; about 4.82 grams/liter of magnesium sulfate; about 1.9 grams/liter of sodium bicarbonate; about 3.85 grams/liter of sodium chloride; about 0.746 grams/liter of potassium chloride. To cleanse the bowel between 3.0 and 4.0 liters of the solution are usually administered to a patient.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: December 4, 1990
    Assignee: E-Z-EM, Inc.
    Inventor: Herbert G. Hechter
  • Patent number: 4960591
    Abstract: A method for relief of stomach distress is disclosed. The method comprises ingestion of a composition comprising non-fat dry milk and sodium bicarbonate. Compositions in particulate or tablet form for relief of stomach distressd comprising non-fat dry milk and sodium bicarbonate are also disclosed.
    Type: Grant
    Filed: April 17, 1989
    Date of Patent: October 2, 1990
    Inventor: Henry G. Gribou
  • Patent number: 4942042
    Abstract: An anti-diarrhea composition comprises diarrhea symptom-reducing amounts of a powdered absorptive material capable of absorbing pathogenic intestinal bacteria, a sodium salt, a potassium salt and a sugar. The absorptive material may be Smectite or mormoiron attapulgite. The salts are preferably NaCl and KCl, with NaHCO.sub.3 also being present. Suitable sugars are glucose and dextrose. The composition may also contain a suspending agent, a coloring agent, a flavoring agent and a sweetening agent. It may be packaged in solid form for admixture with water prior to administration and is preferably moisture protected, for example by the nature of the packaging or by inclusion of a dessicant. The absorptive material may be packaged separately from the salts and sugar. On admixture with water for adminstration, the composition preferably contains, per liter, 2.5 to 15 g of absorptive material, 10 to 30 g of glucose, 60 to 120 mEq of Na.sup.+, 10 to 50 mEq of HCO.sup.- and 10 to 30 mEq of K.sup.+.
    Type: Grant
    Filed: August 29, 1988
    Date of Patent: July 17, 1990
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S. C. A. S.)
    Inventors: Hridaya Bhargava, Jacques Jutteau
  • Patent number: 4880629
    Abstract: A dialytic solution for peritoneal dialysis, which dialytic solution is characterized by containing glycerol and a monosaccharide as osmotic pressure regulating agents for regulating the osmotic pressure to a level necessary for the removal of water.
    Type: Grant
    Filed: April 24, 1986
    Date of Patent: November 14, 1989
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Takeshi Okamoto, Mitsuo Iwata, Hiroaki Takahashi
  • Patent number: 4861582
    Abstract: Dental compositions containing bicarbonate anion in combination with a monovalent anion such as fluoride, chloride or thiocyanate and methods of using them in anti-carogenic, antiplaque and antiperiodontopathic therapy are disclosed herein.
    Type: Grant
    Filed: July 16, 1986
    Date of Patent: August 29, 1989
    Assignee: The Research Foundation of State University of New York
    Inventors: Jerry J. Pollock, Thomas F. McNamara
  • Patent number: 4837021
    Abstract: A tissue irrigating solution useful for irrigating animal tissue, such as ocular tissue and neuro tissue, during surgery, contains sodium, potassium, magnesium calcium chloride, and bicarbonate ions as well as dextrose, glutathione, and gamma-amino butyric acid (GABA) or functional analogue(s) of GABA, or a mixture of GABA and such analogue(s) in proportions consistent with the osmotic stability and continued metabolism of the tissue cells. The irrigating solution is prepared by mixing a first basic solution which provides the bicarbonate and a second acidic solution which provides the calcium, magnesium, dextrose and glutathione. The first and second solutions may be stored as stable, sterile solutions for extended periods of time and mixed within 24 hours of use.
    Type: Grant
    Filed: December 31, 1986
    Date of Patent: June 6, 1989
    Assignee: Laboratoires P.O.S.
    Inventors: Guy Andermann, Georges de Burlet, Michel Dietz, Joseph Spittler
  • Patent number: 4837008
    Abstract: A non-aqueous paste or gel dentifrice composition comprising a water soluble, non-aqueous vehicle having dispersed therein an orally acceptable organic or inorganic peroxide and a bicarbonate salt. The quantities and relative proportions of the peroxide and bicarbonate are sufficient to provide quantities of bactericidally active oxygen upon breakdown of said peroxide by tissue contact and/or by reaction with said bicarbonate in the oral cavity. The bicarbonate also provides a neutral or basic pH upon dissolution of the composition in water. The peroxide and/or bicarbonate is provided with a water soluble barrier coating which is insoluble in the vehicle, to prevent reaction therebetween in the absence of water dissolution of the coating. Normal dentifrice adjuvants may also be present, which can similarly be provided with a water soluble barrier coating.
    Type: Grant
    Filed: January 12, 1987
    Date of Patent: June 6, 1989
    Assignee: Peroxydent Group
    Inventors: Jerome B. Rudy, Melvin Denholtz, Jeffrey R. Denholtz, Peter D. Bohm
  • Patent number: 4834966
    Abstract: A pharmaceutical composition consisting of:Ibuprofen: 33-46% w/wL-arginine: 34-51% w/wSodium bicarbonate: 9-29% w/wis useful for preparing soluble granulate pharmaceutical preparations.
    Type: Grant
    Filed: July 22, 1987
    Date of Patent: May 30, 1989
    Assignee: Zambon S.p.A.
    Inventors: Annibale Gazzaniga, Valter Gianesello, Federico Stroppolo, Vigano Luigi