Abstract: Dispersion containing, in addition to water, 0.5 to 20% by weight of hydrophobic silica, 0.01 to 10% by weight of a gelling additive, or viscosity-increasing additive which, as further components, contains at least one phenol or at least one phenol derivative and/or at least one aldehyde. It is prepared by dispersing the individual components successively or together in water, in which case the individual components are deaerated before and/or during the addition or the dispersion is deaerated during the individual dispersion steps and thereafter the residual air present in the dispersion is removed by application of vacuum. The dispersion can be used as insecticide and for controlling pathogenic agents.

Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure and plurality of pores distributed throughout the scaffold. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material.

Abstract: The present invention discloses an insoluble proton sink or source (PSS), useful for killing living target cells (LTCs), or otherwise disrupting vital intracellular processes and/or intercellular interactions of the LTC upon contact. The PSS comprises (i) proton source or sink providing a buffering capacity; and (ii) means providing proton conductivity and/or electrical potential. The PSS is effectively disrupting the pH homeostasis and/or electrical balance within the confined volume of the LTC and/or disrupting vital intercellular interactions of the LTCs while efficiently preserving the pH of the LTCs' environment. The invention also provides articles of manufacture comprises the PSS and presents an effective method for killing the LTCs.

Abstract: Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.

Abstract: The subject invention provides a process and apparatus for making “enhanced water” that is uniquely suitable for improving circulation, hydration and insulin usage with diabetics. Thus, in a preferred embodiment, the invention provides methods for the treatment and/or prevention of diabetes as well as the prevention or delay in development of diabetes-related complications, conditions or diseases.

Abstract: The invention relates to an anti-inflammatory, wound-healing glass powder, whereby the glass of the glass powder comprises the following components: 20-80 wt. % SiO2, 0-40 wt. % Na2O, 0-40 wt. % K2O, 0-40 wt. % Li2O, 0-40 wt. % CaO, 0-40 wt. % MgO, 0-40 wt. % Al2O3, 0-1 wt. % P2O5, 0-40 wt. % B2O3 and 0-10 wt. % ZnO.

Abstract: Preservative systems on the basis of cationic surfactants are known i n the art, a typical example of such cationic surfactants is the ethyl ester of the lauramide of arginine monohydrochloride (LAE) (2). Besides the chloride form the corresponding bromide and sulphate salts are known. It was found that other salts of the cationic surfactants display excellent properties, such as the salts of lactic acid, glutamic acid and acetic acid. It was further found that the combination of the cationic surfactants with at least one salt of an organic or inorganic acid displayed an excellent preservative action. A further preservative system with favourable properties was the combination of the cationic surfactants with at least one ester compound, amide or enzyme inhibitor. Also the combination of the cationic surfactant with a further cationic molecule such as ethyl arginate, glucosamine or chitosan led to an effective preservative system.

Abstract: The glass flakes of the present invention each include a glass flake substrate and a coating layer coating the surface of the glass flake substrate. The glass flake substrates have an average thickness of 0.1 to 1.0 ?m, and an average particle size of 1 to 100 ?m. The coating layers are formed of methyl hydrogen silicone and the content percentage of the coating layers is 0.05 to 2.50 mass % as determined by ignition loss at 625±20° C.

Abstract: A modified sol-gel method to create metal-rich siliceous material, such as colloidal silica or aluminosilicate particles is disclosed. Initially, the metal salt of choice is added to a silicic acid solution or a silicic acid solution containing aluminum salt. The aluminum is added to vary the metal-support interaction as it forms Al—O—Si linkages within the silica matrix. Besides aluminum, other metals can be added that form M—O—Si (M=Ti, B, etc.) linkages, which do not become reduced when treated with a reducing agent. Once the metal, silicic acid and/or aluminum salt is generated, it is subjected to colloidal growth by addition to a basic heel. Upon colloidal synthesis, the metal salt containing colloidal particle is left as is to maximize colloidal stability or is reduced with hydrazine to produce the zero valence metal-containing colloidal particle.

Abstract: A method for reducing odor is provided. In one embodiment, the method comprises forming a coordination complex between particles having a positive zeta potential and a transition metal. The method further comprises contacting the coordination complex with an odorous compound, the transition metal providing one or more active sites for capturing the odorous compound. For example, in one embodiment, the particles are formed from alumina-coated silica. In addition, the coordination complex may be formed using a bifunctional chelating agent.

Abstract: The inventive material is a unique family of externally used wound sealants based upon a binding agent of reactive submicron silica particles that, when hydrated, agglomerate in the form of a supramolecular cross-linked network serving as the structural framework facilitating clot formation. A thrombolytic cascade accelerant can be provided, optionally with additional clotting factors, to further accelerate the clotting process.

Abstract: A conformable structured therapeutic dressing (120) has maximum available surface area (102) of a therapeutic agent (122) to stimulate therapeutic response in wounded tissue of a mammalian subject. In preferred embodiments, the therapeutic agent includes a procoagulant to quickly arrest bleeding and prevent life-threatening blood loss. The wound dressing exhibits a structured adsorbent (104) that maximizes available surface area of a functional filler (72). This is achieved with a minimal amount of binder (82) and small, porous particles of the functional filler. Minimizing the binder maximizes the amount of functional filler and reduces the chance that the binder will block access to the surface area of the functional filler. Porous particles have a large internal surface area. Structured adsorbents with higher surface areas, higher inter- and intra-fiber porosities, and low internal mass transfer resistances produce higher rates of mass transfer of an adsorbent onto the functional filler.

Abstract: An implant containing a source of oxygen capable of releasing oxygen in the form of molecular oxygen or reactive oxygen species, and a material selected from the group consisting of biodegradable and/or bioactive glass, sol-gel produced silica and mixtures thereof. Also disclosed are uses of the implant and methods of making it.

Abstract: The invention provides the use of silica for cosmetic and/or medical treatment of skin, including improving and enhancing the skin-barrier, anti-aging treatment and photo-protective treatment. The invention is based on the finding that silica exhibits a multi-faceted biological effect useful in the cosmetic and/or therapeutic treatment of skin for the above purposes. Specifically, it has been shown that silica induces markers (involucrin, filaggrin and transglutaminase-1) for skin barrier formation in keratinocytes, induces collagen expression in dermal fibroblasts and inhibits UVA-induced up-regulation of photo-aging markers (matrix metalloproteinase MMP-1 and cytokine IL-6).

Abstract: A natural oriental medicinal composition for the promotion of hair growth is provided. The oriental medicinal composition includes a black bean extract, a tangerine extract, a potato extract, a pine needle extract and a quartzite powder. Since the oriental medicinal composition includes crude drugs extracted from natural substances that can prevent hair loss, it is effective for hair growth and has ensured biostability. Particularly, the oriental medicinal composition allows newborn hair to grow in the form of stiff hair.

Abstract: The present invention relates to a method of treating osteoarthritis by administering a mineral composition in the form of a nutritional supplement, where the mineral composition may contain Smectite, Gypsum, Quartz, Feldspar, Jarosite, Kaolinite and/or Zeolite.

Abstract: The invention relates to a mineral composition for improving well-being and fitness of living beings in general as well as in the presence of equipment emitting non-ionising electromagnetic radiation, comprising a layered phyllosilicate comprising paramagnetic ions and having a conductivity, measured in non-conductive water at a concentration of 1 wt. % of the mineral clay composition relative to the total weight of the non-conductive water and the mineral clay composition, of at most 20 ?S/cm.

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to cholesterol and, thereby, reducing blood cholesterol in a patient. Accordingly, provided herein is a method of reducing hypercholesteremia in a mammal comprising administering to said mammal a protonated and at least partially exfoliated layered phyllosilicate material alone and in combination with other cholesterol-reducing agents in an amount effective to reduce hypercholesteremia in said mammal. Also provided are methods of treating a cardiovascular disorder associated with atherosclerosis in a mammalian subject comprising administering to the subject a layered phyllosilicate material in an amount effective to reduce atherosclerotic lesion formation in the subject.

Abstract: The present invention relates to pigments, the particles of which generally have a length of from 2 ?m to 5 mm, a width of from 2 ?m to 2 mm, and a thickness of from 20 nm to 2 ?m, and a ratio of length to thickness of at least 2:1, wherein the particles contain a core of SiO2 or a silicon/silicon oxide obtained by heating SiOy flakes with 1.1?y?1.8 in an oxygen-free atmosphere at a temperature of at least 400° C., which core has a narrow distribution of particle sizes and two substantially parallel faces, the distance between which is the shortest axis of the core, and a material layer having a high index of refraction a metal oxide; a process for their production and their use in paints, ink-jet printing, for dyeing textiles, for pigmenting coatings (paints), printing inks, plastics, cosmetics, glazes for ceramics and glass.

Abstract: A method for decreasing the time it takes for a wound to heal includes applying hemostatic agent to the wound, inflaming tissue surrounding the wound to facilitate the deposition of fibroblast, thereby accelerating the subsequent contraction of the wound and the onset of the proliferative healing stage, and causing the re-epithelization of the tissue at a faster rate than if no hemostatic agent was applied. A method for promoting the healing of a bleeding wound includes coating a hemostatic agent onto a substrate, applying the substrate to the bleeding wound so that an effective amount of the hemostatic agent is applied to the wound, inflaming the tissue, and causing the re-epithelization of the tissue at a faster rate than if no hemostatic agent was applied. In at least some methods, a clotting cascade and platelet aggregation within the bleeding wound is accelerated, and blood loss from the wound is decreased.

Abstract: The present invention features a composition for regulating the firmness, tone, or texture of skin, or for regulating wrinkles, or for the treatment of external aggression in skin containing a safe and effective amount of a Feverfew extract and a cosmetically-acceptable topical carrier, and the use thereof.

Abstract: A bioabsorbable material suitable for implanting within a human body, the material including fibers of a composite of a synthetic bioabsorbable polymer such as poly-lactic acid, and a particulate bioactive filler such as calcium phosphate powder. The fibers are discontinuous with non-uniform cross-sections and non-uniform cross-sectional areas. The surface topography provided by the fibers provides a substrate which is more amenable to cellular colonization than prior materials.

Abstract: Described herein are compositions and methods related to wound treatment. Compositions are multi-components admixed in amounts and ratios to meet specific objectives for optimally treating various types of wound injury.

Abstract: The invention includes an alkali metal silicate based solution that, either alone or following an alkali earth metal salt activator, binds soluble phosphorus and/or nitrates.

Abstract: The present invention relates to compositions comprising a silicate and methods of use thereof. In particular, the compositions of the present invention are suitable for treating inflammatory conditions, cancer, bacterial and viral infections, and infected and uninfected wounds. The compositions of the present invention can also be useful in treating spinal cord injury, tissue remodeling, and promoting bone growth and repair.

Abstract: The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention is a method to repel rather than kill insects, arachnids, and other arthropods utilizing materials taken from the EPA's GRAS (Generally Recognized as Safe) List, obviating onerous Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) regulations and greatly extends the useful life of the insect-repellant materials by binding them into the dried film solids—greatly slowing their evaporation and degradation and creating a timed release of insect repellant material. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the surrounding area during coating application, thereby eliminating the need for applying insect repellants such as DEET to the skin.

Abstract: A vitreous antimicrobial agent that can exhibit excellent antimicrobial properties when added to various types of resins, that has excellent discoloration resistance and hot water resistance, and that can easily be produced at a commercial scale. The vitreous antimicrobial agent includes, relative to 100 mass % of total glass components, 0.1 to 2 mass % of Ag2O, 40.5 to 49 mass % of ZnO, 6 to 9.5 mass % of SiO2, 30.5 to 39.5 mass % of B2O3, 2 to 10 mass % of an alkaline earth metal oxide, and 6 to 7.5 mass % of Na2O; the vitreous antimicrobial agent comprising, in addition to these, 0.01 to 5 mass % of CeO2 as necessary. An antimicrobial resin composition and an antimicrobial product including the vitreous antimicrobial agent.

Abstract: Methods and compositions are provided for the persistent modification of cell membranes with exogenous proteins so as to alter the function of the cell to achieve effects similar to those of gene therapy, without the introduction of exogenous DNA. DNA sequences, the proteins and polypeptides embodying these sequences are disclosed for modulating the immune system. The modulations include down-regulation, up-regulation and apoptosis.

Abstract: The invention is a silicon substituted oxyapatite compound (Si—OAp) for use as a synthetic bone biomaterial either used alone or in biomaterial compositions. The silicon substituted oxyapatite compound has the formula Ca5(PO4)3-x(SiO4)xO(1-x)/2, where 0<x<1.0.

Abstract: Disclosed are pharmaceutical compositions suitable for oral administration of bioactive peptides. Particularly, the pharmaceutical compositions comprise peptides formulated as suspensions stabilized with a dispersing agent. The compositions may be encapsulated in capsules for oral administration. The compositions show improved dissolution characteristics, which are believed to make them suitable for use in the treatment of gastrointestinal disorders.

Abstract: Process to delay the release of water from a pulverulent preparation comprising cosmetic products, cleaning agents and detergents, wherein the pulverulent preparation contains at least 50 wt. % of water and a hydrophobed silicon dioxide powder, wherein the pulverulent preparation is in contact with a hydrophobic material during storage.

Abstract: The present invention relates to a biocidal composition, a method for its production and the use of the biocidal composition.

Abstract: The invention relates to a pigment mixture consisting of at least two constituents, constituent A being uncoated, monocoated or multicoated glass lamellae, and constituent B being nacreous pigments based on phyllosilicates, SiO2 lamellae, Fe2O3 lamellae or Al2O3 lamellae. The invention also relates to the use of said pigment mixture, inter alia, in paints, dyes, especially printing inks, plastics, powder paints, pastes and cosmetic formulations.

Abstract: The invention relates in particular to the cosmetic use of a composition containing, in a physiologically acceptable medium, an effective amount of at least one mosaic-effect tensing agent for improving the thickness of the skin and/or promoting the radiance of the complexion. The invention also relates to the cosmetic use, in a composition containing a physiologically acceptable medium, of an effective amount of at least one mosaic-effect tensing agent as an agent intended to improve the firmness and/or elasticity and/or tonicity of the skin. The invention likewise relates to a cosmetic method of treatment of dull and/or poorly defined complexion that comprises the topical application of a composition comprising at least one mosaic-effect tensing agent to people who have a dull and/or poorly defined complexion. Mosaic-effect agents of this kind are selected in particular from (i) mineral tensing agents and (ii) tensing polymers.

Abstract: A process of preparing a biogenic silica comprising the steps of incinerating a silica bearing organic source at a temperature up to 1200° C. and allowing the incinerated silica organic source to cool; adding the incinerated and cooled silica bearing organic source to an alkaline solution that has either been preheated to a temperature up to about 65° C. or to be heated with the added organic source to a temperature up to about 65° C., the alkaline solution being contained in a vessel and having a pH up to 14; applying heat so that the added organic source and the alkaline solution in the vessel are at a temperature between 100° C. and up to about 300° C. for 1 to 4 hours, thereby forming an aqueous biogenic silica and undissolved impurities derived from the added organic source; and extracting the aqueous biogenic silica from the vessel. The extracted silica can be solidified into a solid form.

Abstract: The present invention relates to a cosmetic composition of coverage that is greater than or equal to 25, better 30, said composition including, in a cosmetically-acceptable aqueous medium, at least one multilayer interference pigment at a content that imparts to the composition, a variation in color ?E on application that is greater than or equal to 5.

Abstract: The present invention relates to a cosmetic composition comprising: a physiologically-acceptable medium; and at least 15% by weight, relative to the total weight of the composition, of monodisperse particles having a mean size lying in the range 80 nm to 500 nm, the monodisperse particles being suitable for forming an ordered lattice of monodisperse particles on a substrate onto which the composition is applied.

Abstract: A skin care composition for regulating sebum flow from sebocytes is described. The composition comprises spheroids, and optionally, thickening agents and when a spheroid and sebum mixture is made upon application, the resulting mixture leaves a pleasant, silky and powdery sensation.

Abstract: A multi-dimensional hair sustaining formulation having a liquid transport agent that carries multi-ingredients to hair follicles in order to prevent Dihydrotestosterone (DHT) from attaching to receptor sites on the follicles of existing hair, hence promoting the growth of existing hair which otherwise would succumb to DHT attack.

Abstract: The present invention relates to a line of cosmetic compositions comprising at least two compositions each comprising a cosmetically-acceptable medium and at least one multilayer interference pigment, each composition providing coverage that is greater than or equal to 25, the respective multilayer interference pigments of the various compositions being selected in such a manner that the colors of the compositions in the mass, taken two by two, differ by a color difference ?Ebeforeapplication that is less than or equal to 3, and in such a manner that, after application, the compositions, taken two by two, present a color difference ?Eafterapplication that is greater than or equal to 5.

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. Accordingly, provided herein are methods of inactivating a virus and methods of treating a viral infection. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in the gastrointestinal tract of an animal are also provided.

Abstract: The invention relates to a medical device comprising non-sintered bioactive glass particles or fibres having a diameter in the range 5-100 ?m, bioactive glass comprising SiO2, Na2O, CaO, K2O, MgO, B2O3 and P2O5, wherein the amount of SiO2 is 50-65 wt-% of the final total weight, Na2O is 5-26 wt-% of the final total weight, CaO is 10-25 wt-% of the final total weight, K2O is 0-15 wt-% of the final total weight, MgO is 0-6 wt-% of the final total weight, B2O3 is 0-4 wt-% of the final total weight, and P2O5 is 0-4 wt-% of the final total weight, provided that the total amount of Na2O and K2O is 10-30 wt-% of the final total weight The device is essentially drug free. The invention also relates to the use of said composition for treating lesions associated with compromised or poor vascularisation and for preventing avascular fibrosis.

Abstract: A particulate composition comprises from 40 to 80% by weight of a water-soluble saccharide, from 1.5 to 10% by weight of a finely particulate amorphous hydrophobic silica having a surface area in the range of from 80 to 300 m2/g and water. The composition is in the form of fine particles of an aqueous solution of the water-soluble saccharide, the surfaces of which fine particles of aqueous solution are coated with a coating of the finely particulate amorphous hydrophic silica. The composition, which may additionally contain one or more biocidally-active materials, can be applied through conventional dust applicator equipment for the treatment of pests.

Abstract: The present invention relates to a nutritional supplement composition and methods for preparing. The invention further provides a method for creating a nutrient supplement drink composition comprising the a carrier liquid, a flower distillate, and at least one herbal extract component, and optionally including an additional ingredient selected from the group consisting of a second herbal extract component, a nutrient, a flavoring agent, a preservative, a coloring agent, a second carrier agent, and combinations thereof.

Abstract: A lipolysis stimulator and a slimming agent which stimulate or facilitate lipolysis of accumulated adipose tissue, to thereby exert the body slimming effect. The lipolysis stimulator or the slimming agent of the present invention contains as an active ingredient any form of a plant or an extract thereof, the plant being selected from among common juniper, togenashi, rosehip, areca, polygala root, plantago herb, calumba, zuikorodoku, garden nasturtium, kidachiumanosuzukusa, bayberry, cogon grass, kohon, shoyokanzo, Japanese white birch, tanjin, kikubafuro, white mustard, common sunflower, ground ivy, Chinese wolfberry, Japanese pagota tree, sennenken, common fig, kankatto, Chinese hibiscus, usubaakaza, fenugreek, English walnut, sozuku, koniwa-zakura, gardenia, shima-kan-giku, akamino-akane, futaba-mugura, karoou, schizonepeta spike, purslane, karabyakushi, and prostrate knotweed.

Abstract: The method of protecting a polymeric plastic from attack by bacteria and fungi includes providing bioactive glass particles having a mean particles size preferably less than 2 ?m as an additive incorporated into the polymeric plastic. The bioactive glass particles contain 40 to 60% by weight of SiO2, 10 to 30% by weight of CaO, 10 to 35% by weight of Na2O, 2 to 8 % by weight of P2O5, 0 to 25% by weight of CaF2, 0 to 10% by weight of B2O3, 0 to 8% by weight of K2O and/or 0 to 5% by weight of MgO. The additive is included in amounts of up to 25% by weight in the polymeric plastic.

Abstract: A composition contains an inorganic substance obtained as a residue after incinerating skins of marine organisms, and chitin/chitosan. The composition is obtained by incinerating the skins of the marine organisms at a temperature within a range between 600° C. and 1000° C. to obtain the inorganic substance as a residue, obtaining a powdered inorganic substance from the inorganic substance, and kneading the powdered inorganic substance with chitin/chitosan powder.

Abstract: The present invention relates to a powder mixture for resorbable calcium phosphate biocements, which mixture consists of 40–99% by volume of powder having a particle size of 0.1–10 ?m, 1–20% by volume of powder having a particle size of 10–43 ?m and 0–59% by volume of powder having a particle size of 43–315 ?m, which powder is obtained by grinding the spontaneously crystallizing melts of a material comprising crystalline and X-ray amorphous phases, which material a) according to 31P-NMR measurements, contains Q0-groups of orthophosphate and Q1-groups of diphosphate, the orthophosphates or Q0-groups making up 65 to 99.9% by weight relative to the total phosphorus content of the powder mixture and the diphosphates or Q1-groups making up 0.1 to 35% by weight relative to the total phosphorus content of the powder mixture, and b) according to X-ray diffractometric measurements and relative to the total weight of the powder mixture, contains 35 to 99.

Abstract: A resorbable silica-calcium phosphate bioactive composite that finds utility for drug delivery. The bioactive composite is loaded with a pharmaceutical composition and releases a therapeutically effective amount of a pharmaceutical composition for periods of up the 28 days.

Abstract: Silicatein is an enzyme of silicate-forming organisms used for the synthesis of their silicate scaffold. The present invention relates to the use of highly-expressed and highly active recombinant silicatein, silicatein isolated from natural sources after gene induction as well as silicatein-fusion proteins for the synthesis of amorphous silicon dioxide (silicic acids and silicates), siloxanes as well as modification of these compounds and their technical use.