Containing Or Obtained From Vaccinium (e.g., Bilberry, Cranberry, Blueberry, Etc.) Patents (Class 424/732)
  • Patent number: 6391345
    Abstract: The present invention includes a cranberry seed oil, a cranberry flour and a method for making cranberry seed oil and flour. The cranberry seed oil comprises beta sitosterol and phosphatidylcholine.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: May 21, 2002
    Inventors: Tim Heeg, Bernard G. Lager, II
  • Patent number: 6387370
    Abstract: Compositions and methods are provided for reducing oxysterol buildup in the blood and normalizing cholesterol and blood pressure, in a mammal. The compositions comprise Morinda citrifolia extract, red wine extract, prune extract, blueberry extract, pomegranate extract, apple extract, and an enzyme mixture.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: May 14, 2002
    Inventor: Inna Yegorova
  • Publication number: 20020054924
    Abstract: Novel compositions derived from grapefruit and cranberry are disclosed, as well as therapeutic uses for the compositions in treating or preventing cancer and hypercholesterolemia in a subject. The compositions are, in particular embodiments, derived from grapefruit essence oil, grapefruit peel oil, grapefruit peel, and decharacterized cranberry fruit.
    Type: Application
    Filed: April 13, 2001
    Publication date: May 9, 2002
    Inventors: Margaret M. Leahy, Martin Starr, Elzbieta Kurowska, Najla Guthrie
  • Publication number: 20020048611
    Abstract: A non-food anti-microbial-adhesion and aggregation composition comprising a suitable carrier and an effective amount of an adhesion inhibitory fraction isolated from juice from berries of the Vaccinium plant genus. In an embodiment the anti-aggregation and adhesion fraction is isolated from cranberry juice. It is characterized as being polymeric and having a molecular weight ≧14,000; an elemental analysis of carbon 43-51%, hydrogen 4-5%, no nitrogen, no sulfur and no chlorine; a nuclear magnetic resonance (NMR) line spectrum as set forth in FIGS. 2A and 2B; and an ultraviolet spectrum with an absorption peak at 280 nm in neutral or acidic pH solution which is absent in alkali solutions. This fraction exhibits adhesion inhibitory activity against P fimbriated bacteria, oral bacteria and Helicobacter pylori.
    Type: Application
    Filed: July 27, 2001
    Publication date: April 25, 2002
    Inventors: Itzhak Ofek, Ervin Weiss, Yoel Kashman, Janina Goldhar, Nathan Sharon
  • Publication number: 20020028260
    Abstract: Compounds isolated from plant materials, particularly plants of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, and an extract of such plant materials which is significantly enriched for the anti-adhesion activity. The specific compounds include procyanidins (also known as “condensed tannins”), leukocyanin, leucodelphinin, flavonol glucosides including myricetin-3-pyranoside and proanthocyanidin extracts. These proanthocyanidin extracts are capable of inhibiting agglutination reactions of P-type E. Coli. The extracts containing proanthocyanidins contain at least one A-type interflavanoid bond. Methods of making an extract.
    Type: Application
    Filed: August 1, 2001
    Publication date: March 7, 2002
    Inventors: Edward B. Walker, Richard A. Mickelsen, Jennifer N. Mickelsen
  • Publication number: 20020009504
    Abstract: Compositions and methods for treating eye discomfort are provided. The compositions comprise singly or in combination herbals, natural nutritional supplements, minerals and vitamins. Methods of making these compositions are also provided.
    Type: Application
    Filed: June 1, 2001
    Publication date: January 24, 2002
    Inventor: Yuanjin Tao
  • Publication number: 20010036487
    Abstract: A composition and method for stabilizing proanthocyanidin, especially for preventing, for example, its discoloration by oxidative polymerization. The method utilizes (and the composition contains) proanthocyanidin, and an amino acid having a hydroxyl group or a dipeptide containing said amino acid. Also shown is a drink, food, cosmetic or medicament which contains the composition.
    Type: Application
    Filed: March 20, 2001
    Publication date: November 1, 2001
    Inventors: Tomoya Takahasi, Asako Kabayashi
  • Publication number: 20010031744
    Abstract: This invention relates to nutrient and therapeutic compositions for treatment and prevention of symptoms and disease conditions associated with microangiopathy and macroangiopathy and to methods using the compositions. In particular, the invention relates to compositions useful in the treatment of diabetic retinopathy and nephropathy, to compositions useful in the treatment of other retinal disorders including macular degeneration and cataracts, to compositions useful in wound healing, to compositions useful for treatment and prevention of neuropathy, to compositions useful for treatment and prevention of cardiovascular disease and to compositions useful for the treatment and prevention of dental and periodontal disorders.
    Type: Application
    Filed: April 5, 2001
    Publication date: October 18, 2001
    Inventor: John V. Kosbab
  • Publication number: 20010025059
    Abstract: A composition and a method for treatment of prostate related dysfunction and, particularly, non-bacterial prostatitis and, even more particularly, non-bacterial chronic prostatitis. The composition primarily relies upon the use of a bioflavonoid and, particularly, that bioflavonoid known as quercetin. The quercetin is mixed with a proteolytic digestive enzyme protease, such as bromelin and papain, as the primary active ingredients. However, the composition may optionally and beneficially include other prostatitis affecting agents, such as zinc derived from zinc gluconate, cranberry, saw palmetto, as well as some other active and non-active ingredients.
    Type: Application
    Filed: January 9, 2001
    Publication date: September 27, 2001
    Inventor: Floyd A. Kastke
  • Publication number: 20010021398
    Abstract: Compounds isolated from plant materials, particularly plants of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, and an extract of such plant materials which is significantly enriched for the anti-adhesion activity. The specific compounds include procyanidins (also known as “condensed tannins”), leukocyanin, leucodelphinin, flavonol glucosides including myricetin-3-pyranoside and proanthocyanidin extracts. These proanthocyanidin extracts are capable of inhibiting agglutination reactions of P-type E. coli. The extracts containing proanthocyanidins contain at least one A-type interflavanoid bond. Methods of making an extract.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 13, 2001
    Inventors: Edward B. Walker, Richard A. Mickelsen, Jennifer N. Mickelsen
  • Publication number: 20010014351
    Abstract: The present invention relates to a process for providing non-lipid, liquid form herbal extracts in a vegetable gelatin, HPMC, or any other cellulose derivative capsule. The process includes extracting an herbal plant material with an alcohol to provide an aqueous alcoholic herbal extract. The aqueous alcoholic herbal extract is contacted with sufficient glycerin to maintain the extract preferably in solution, and at least dispersed in the mixture of glycerin and aqueous alcoholic herbal extract. Alcohol and water is removed form the mixture to provide a glycerin-based liquid or semi-solid herbal extract and having a moisture content of less than 10 percent by weight, and preferably less than 5 percent by weight. The herb extract is then encapsulated in a vegetable gelatin, HPMC, or any other cellulose derivative capsule.
    Type: Application
    Filed: February 1, 2001
    Publication date: August 16, 2001
    Inventor: Xiping Wang
  • Publication number: 20010012525
    Abstract: Disclosed is a method of producing a reconstituted fruit, herb, and/or seed fiber product, the product produced using the method, and dietary supplements containing the product. The steps used to produce the product include expressing juice from a fruit, herb, or seed; concentrating the juice by removing water; infusing pomace obtained during expression of the juice with the concentrated juice, and drying the steeped pomace to obtain a dry, non-hygroscopic, free-flowing nutritional supplement.
    Type: Application
    Filed: February 20, 2001
    Publication date: August 9, 2001
    Inventor: Douglas L. Mann
  • Patent number: 5830755
    Abstract: The present invention provides nucleic acid sequences for T-cell receptors which recognize tumor associated antigens. In particular, T-cell receptors which recognize melanoma antigens. This invention also provides T-cells expressing the antigen specific T-cell receptors. In addition, this invention provides stem cells expressing the antigen specific T-cell receptors or chimeric receptors. This invention further relates to therapeutic and diagnostic compositions and methods employing the T-cell receptors and chimeric receptors provided herein.
    Type: Grant
    Filed: March 27, 1995
    Date of Patent: November 3, 1998
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Michael Nishimura, Steven A. Rosenberg