Abstract: An oral herbal composition comprising a therapeutically effective amount of an extract derived from the berries of a plant, Piper cubeba, wherein the composition is provided for use in the treatment of oral candidiasis (oral thrush). The oral herbal composition can be formulated in the form of a candy, a chewable tablet and an oral gel. The herbal composition exhibits antifungal activity against azole resistant strains of Candida albicans. The herbal composition is safe to administer and has improved patient compliance.

Abstract: The present invention provides a composition for accelerating a change in muscle type, increasing the amount of muscle, strengthening muscle, enhancing athletic abilities, reducing lipids, suppressing the accumulation of lipids, lowering blood sugar, controlling body weight or lowering body weight, containing a PPAR-? promoter, an AMPK promoter and a PGC1-? promoter as an active ingredient

Abstract: A liquid animal repellent composition having a liquid phase and an oil phase, the composition having oleoresins of capsicum, black pepper and rosemary along with surfactants and preservatives. A pH adjuster is also utilized.

Abstract: A dietary supplement for regulating the appetite of an individual is described. The dietary supplement comprises at least one mechanical satiety regulator, and at least one chemical satiety inducer, and may additionally comprise at least one thermogen, and/or at least one side effect remover. The dietary supplement induces satiety based on a combination of occupying part of the volume of the stomach, inducing sending signals to the brain in respect of satiety. Furthermore the dietary supplement may maintain or increase metabolism and reduce side effects such as the amount of produced flatulence. The dietary supplement may comprise fibre, whey, plant parts from plants e.g. of the genus Capsicum and plant parts from a species e.g. of the genus Mentha.

Abstract: For enhancing bioavailability, a composition is administered comprising a Transient Receptor Potential cation channel subfamily V member 1 (TRPV1) agonist with a combined Scoville Heat Unit (SHU) milligram (mg) dose in the range of 280,000 to 400,000 SHU mg.

Abstract: The present invention has discovered that flavone glycosides represented by Formula I set forth below have unexpected and advantageous flavor enhancement and modification properties: wherein R1 is selected from the group consisting of H and CH3, R2 is selected from the group consisting of H and OH, and R3 is a 7-O-glycoside. Thus, the flavone glycosides of the present invention can be used to enhance or modify the flavor of orally consumable compositions, such as foodstuff, chewing gums, dental and oral hygiene products, and medicinal products.

Abstract: The present invention relates to an abuse-proofed, thermoformed dosage form containing, in addition to one or more active ingredients with abuse potential optionally together with physiologically acceptable auxiliary substances, at least one synthetic or natural polymer with a breaking strength of at least 500 N and to a process for the production thereof.

Abstract: Described herein are compositions comprising a combination of extracts, and methods of preparing and using the same.

Abstract: The invention discloses phytochemical agents derived from Holoptelea integrifolia and novel composition(s) comprising at least one component selected from the extract(s), fraction(s) and active compound(s) for the protection and alleviation of Metabolic Syndrome, insulin resistance, endothelial dysfunction, chronic kidney disease, atherosclerosis, diabetes and other disease conditions associated with metabolic syndrome. The invention also discloses the amelioration of certain biomarker molecules such as Peroxisome proliferator-activated receptor gamma (PPAR-?), Adipose Differentiation Related Protein (ADRP), CD36, Adipocyte Fatty-acid-Binding Protein (aP2/FABP-4/A-FABP), beta-3 Adrenergic Receptor (?3AR), Leptin, Perilipin and Adiponectin by using the phytochemical components derived from Holoptelea integrifolia.

Abstract: Disclosed is a herbal solid formulation comprising Andrographis paniculata, Terminalia arjuna, Azadirachta indica, Trikatu (Zingiber officinalis, Piper longum, Piper nigrum), Tinospora cordifolia or Ocimum sanctum extracts essentially free of excipients and preservatives and process for preparing the same.

Abstract: Disclosed are dietary nutritional supplements providing health benefits. Supplements provide various formulations of fermented soybean in combinations with sweetener(s), curcumin, and various other herbs and spices. Compositions are preferably in liquid or solid forms. In preferred embodiments of the invention, supplements have HAELAN 951® or dehydrated fermented soy made from HAELAN 951®, Curcumin C3 Complex®, sucralose, stevia, soy lecithin, barley malt, natural chocolate flavor, cocoa, BIOPERINE®, Piper longum, ginger, cardamom long, and cinnamon.

Abstract: A repellent formulation comprising an amount of Neem Oil. The present invention provides, for the first time, a repellent formulation that, rather than chemically affecting the food supply of birds, acts by imparting a bitter and unpleasant taste when the repellent is transferred from the birds feet and feathers to its mouth when preening.

Abstract: The present invention relates to a bio-pesticide comprising a mixture of natural spices that kills insects through direct contact. Piper Nigrum, Cuminum Cyminum, Cinnamomum Verum, Allium Sativum, Coriandrum Sativum, Curcuma, Foeniculum Vulgare, Trigonella Foenum Graecum, Syzygium Aromaticum, Capsicum, Zingiber Officinale, Murraya Koenigii, Brassica Nigra, and Sodium Chloride are mixed with potting soil and applied to a plant. The bio-pesticide works through the processes of repellency, digestive inhabitancy, paralysis and suffocation. The bio-pesticide can be applied as a dust or liquid spray to the plants, and can eliminate the pests within 48-72 hours.

Abstract: In one embodiment, a composition containing ergothioneine and/or synthesized l-ergothioneine and one or more compounds selected from the group consisting of vitamin B-12, glucosamine sulfate, calcium ascorbate, turmeric extract, black pepper extract, hyaluronic acid, collagen, glycosaminoglycans, cat's claw extract, acai berry; and white willow bark extract is provided to a mammal to improve a variety of health related factors, including but not limited to brain health, joint health, eye health, mitondchorial optimization/improvement and reduction of inflammation and pain in a mammal.

Abstract: A nutritional supplement includes the primary ingredients: N-acetyl D-glucosamine, cracked cell wall Green Chlorella, Licorice Root Extract, and Potassium Citrate, as well as secondary ingredients: Zinc L-Carnosine, Gamma-Oryzanol and Capsaicin, that improves the bodies uptake, utilization and over-all bioavailability of exogenous target protein fractions (TPF) including but not limited to: glycoproteins, (such as glucosamine) protein isolates as amino acids, glycosaminoglycans (GAG) (including proteoglycans, and mucopolysaccharides), and polysaccharides such as hyaluronic acid (hyaluronan). The biochemical interactions of the composition improves zeta potential for TPF incorporation in the body through direct and indirect interaction with primary cellular and digestive sites of multiple species.

Abstract: The present invention relates to a herbal composition for treating gastric ulcer, a method for preparing said herbal composition.

Abstract: A formulation to treat rheumatic disorders and related infections is provided. The formulation is a micro-emulsion including at one or more of an active ingredients. The active ingredient includes one or more of an essential oil mixed with an aqueous phase along with one or more of a surfactant and one or more of a co-surfactant. The co-surfactant is medicated by an extract of one or more of an herb.

Abstract: An edible product for normalizing blood sugar levels is provided. The product includes a mulberry extract having a (w/w) flavonoids concentration of at least 10%, a 1-deoxynojirimycin (DNJ) concentration of about 2% and a GABA concentration of about 1% of the total amino acid content of said mulberry extract.

Abstract: The present disclosure relates to the combined use of two pesticides. A first pesticide composition provides an initial contact kill, and may form a barrier when applied to greasy surfaces. A second pesticide composition provides residual pesticidal activity on the surface. Methods of making and using the pesticide compositions are also provided.

Abstract: The present disclosure relates to water dispersible granular pesticide compositions, and methods of making and using the compositions. The pesticide compositions include an inner layer including a first pesticide coated on to a substrate, and an outer layer comprising a second pesticide coated on the inner layer. The outer layer increases the water dispersibility of the granular composition, and protects the first pesticide against hydrolysis and photolysis.

Abstract: The invention provides a formulation for the prevention and treatment of bacterial infections by administering an effective amount of the formulation comprising an extract of at least one plant selected from Allium sativum, Acorus calamus, Alstonia scholaris, Carissa spinarum, Cissampelos pareria, Chenopodium ambrosioides, Moringa olifera, Paederia foetida, Shorea robusta, Piper nigrum, Pueraria tuberosa, Ocimum sanctum, Terminalia bellirica, Tinospora cordifolia and Zingiber officinale, and a combination thereof. The invention also provides a process for preparing and method of using the same.

Abstract: An improved plant medicament composition, comprising a mixture of extractions of Piper guineense, Eugenia caryophyllum and Sorghum bicolor plant material, without the use of Pterocarpus osun stem, for treating sickle cell disease is disclosed. A method for the preparation of said composition is also provided.

Abstract: A stabilized formulation for skin care, wound care and/or other tissue healing applications and methods for making the same is described. The stabilized formulation stabilizes omega-3 polyunsaturated fatty acids and is constituted of the omega-3 polyunsaturated fatty acids in combination with tocopherol (Vitamin E), ascorbic acid (Vitamin C), herb extract, and a fat-soluble antioxidant. Methods for making and using the stabilized formulation are also described.

Abstract: Provided are methods for extracting flavor and fragrance materials from natural plant materials, using poly(trimethylene ether) glycol homopolymers and copolymers. The poly(trimethylene ether) glycol homopolymers and copolymers act as solubilizers for essential oils, and can be used to provide compositions having a variety of uses in applications such as cosmetics, personal care products, and industrial cleaning products.

Abstract: Disclosed are a starting material, and a manufacturing method therefor, which starting material contains a lipophilic component with flavors or odors typical of pungent components, such as capsaicin, and bitter components, such as turmeric extract, and which is able to effectively suppress the taste and/or odor of the lipophilic component, while also not causing the ingredients to separate. Also disclosed is a composition for food and drink, cosmetics, and medicine, etc., to which this starting material is added. Further disclosed is a liquid composition in a form in which said starting material is dispersed in water. Provided is a complex that contains a lipophilic component, a substance (A) selected from a group comprising plant sterols, ?-oryzanol, isoflavone, vitamin D, vitamin E, vitamin K, and combinations thereof, and cyclodextrin. Also provided is a composition to which the complex has been added.

Abstract: A composition and a method for using the composition to delay the onset of the symptoms of Alzheimer's disease in humans, comprising curcumin, piperine, oleic acid, oleanolic acid, ursolic acid, galantamine, and huperzine A, among other compounds. Curcumin is an antioxidant, while galantamine and huperzine A inhibit the activity of acetylcholinesterase in the brain. Piperine and oleic acid increase the bioavailability and gastrointestinal absorption of curcumin, galantamine, huperzine A, and other nutrients.

Abstract: A comestible composition with anti-cancer property comprises alcohol soluble extracts from plant parts of Piper species, palm species, tropical seaweeds, and/or Solanum species.

Abstract: A medicinal composition comprising an apportioned combination of at least eight essential oils selected from the group consisting of calophyllum inophyllum, citrus aurantium, eucalyptus globulublus, eugenia caryophyllata, foeniculum vulgare, helichrysum angustifolia, juniperus virginiana, lavendula officinalis, muristica fragrans, ocimum basilicim, pinus sylvestrius, piper nigrum, rosemarinus officinalis, salvia officinalis lamiacae, salvia sclarea and zingiber officinale. When configured for topical dermal application, this composition has been shown to be therapeutically effective at relieving pain.

Abstract: Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n—, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

Abstract: Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n—, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

Abstract: Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n— wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

Abstract: Disclosed herein is synergistic herbal composition comprising extracts of herbal ingredients of Tribulus terrestris, Withania somnifera, Curculigo orchioides, Mucuna pruriens, Asparagus adscendens, Asteracantha longifolia, Asphaltum, and optionally the extracts of Piper longum and Anacyclus pyrethrum for the treatment of disorders associated with Male Sexual Dysfunction.

Abstract: The present invention relates to a method for inhibiting the activity of dipeptidyl peptidase-IV (DPP-IV) and decreasing blood glucose levels.

Abstract: The present invention relates to the combination of a plant extract, such as oregano extract and a polyunsaturated fatty acid or a derivative (such as an ethyl ester “PUFA EE”) which is stable under strorage conditions.

Abstract: The present invention provides a proprietary compositions and systems to modulate genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well as the metabolism, efficacy and/or toxicity associated with specific vitamins, minerals, herbal supplements, homeopathic ingredients, and other ingredients for the purposes of customizing a subject's nutritional supplement formulation to optimize specific health outcomes. Specific to this invention the utilization of certain known polymorphic genes associated with Substance Use Disorder (SUD) are analyzed to target certain genetic anomalies that lead to a high risk and predisposition to SUD. The genotypic patterns are then utilized to provide certain nutritional customized solutions especially related to the attenuation of aberrant abuse of physician prescribed narcotic pain medication across all pain conditions.

Abstract: This invention relates to method of treating human malignancies of different origin that are sensitive to oxidative stress by administering effective amount of extract of Piper betel leaves along with a pharmaceutically acceptable additives

Abstract: The present invention relates to a method for the preparation of a dry extract from the fruit of Piper cubeba L., which characterized in that, in a first step, the fruit of Piper cubeba L. either is subjected to a steam distillation for the removal of essential oils and the distillate is removed or extracted at least once with a lipophilic phase and the lipophilic extract or extracts are removed; in a second step, the fruit, so treated, is extracted at least once either with at least one alcohol or with a mixture of at least one alcohol and water; and, in a third step, the extracted fruit parts are removed and an auxiliary material is added to the extract so obtained, which is then concentrated to a thick extract with an alcohol concentration of 0.1 to 10% (w/w), then dried and recovered.

Abstract: A composition and method for promoting weight loss through the mutual and simultaneously to promotion lipolysis, the expenditure of energy stored in the body as fat, the inhibition of lipolysis as well as affording the body of an individual protection from reactive oxygen species resulting from the ?-oxidation of fats. The composition comprises at least a lipolytic substance, a thermogenic substance, a substance to inhibit the reformation of triglycerides in the bodily tissues of an individual and an antioxidant.

Abstract: An animal repellent composition is disclosed that comprises a carrier base and a repellent material. The carrier base and the repellent material are mixed together in a resulting formulation that is used to provide a natural means of deterring unwanted pests and animals from the area in which the composition is used. The composition may also be used as an animal attractant depending on the formulation of the mixed materials. The formulation of the composition can be varied to produce mixtures with different consistencies and properties.

Abstract: An oral herbal composition comprising a therapeutically effective amount of an extract derived from the berries of a plant, Piper cubeba, wherein the composition is provided for use in the treatment of oral candidiasis (oral thrush). The oral herbal composition can be formulated in the form of a candy, a chewable tablet and an oral gel. The herbal composition exhibits antifungal activity against azole resistant strains of Candida albicans. The herbal composition is safe to administer and has improved patient compliance.

Abstract: A composition and method for promoting weight loss through the mutual and simultaneously to promotion lipolysis, the expenditure of energy stored in the body as fat, the inhibition of lipolysis as well as affording the body of an individual protection from reactive oxygen species resulting from the ?-oxidation of fats. The composition comprises at least a lipolytic substance, a thermogenic substance, a substance to inhibit the reformation of triglycerides in the bodily tissues of an individual and an antioxidant.

Abstract: Disclosed is an effervescent composition that includes a viscous component is in the form of a free flowing granulation, a tablet made from the free flowing granulation, and a method of using the effervescent composition.

Abstract: The present invention provides a novel liquid animal repellant composition which is environmentally safe, non-toxic, long-lasting and efficacious against a wide of animals such as dogs, cats, raccoons, skunks, mice, rats, squirrels, chipmunks, deer, etc.

Abstract: A kit including a first composition comprising leaves of Melissa officinalis, or parts thereof; a second composition comprising Eleutherococcus senticosus, or parts thereof; a third composition comprising Avena sativa, or parts thereof; a fourth composition comprising Ballota nigra, or parts thereof; a third composition comprising the roots of Glycyrrhiza glabra/gan cao, or parts thereof; and a sixth composition comprising roots of Uncaria tomentosa, or parts thereof. The invention further relates to a kit for use as a medicament, to a kit for use in the treatment of disorders in mammals, like humans, horses, cows, pigs and pets, to a kit for use in the treatment of lupus, multiple sclerosis, rheumatoid arthritis, rheumatism, osteoporosis, asthma in humans or tale and mane eczema in horses, and to the use of the kit for the treatment of lupus, multiple sclerosis, rheumatoid arthritis, rheumatism, osteoporosis, asthma in humans or tale and mane eczema in horses.

Abstract: Compositions and methods relating to partially hydrolyzed fucoidan for use in dietary supplements are described. Fucoidan from brown seaweeds is partially hydrolyzed and then mixed with other ingredients for use as a dietary supplement in beverage, capsule, or tablet form. The fucoidan is partially hydrolyzed with acid and heat. The partially hydrolyzed fucoidan can also be sulfonated. Other ingredients that can be included in the dietary supplement include high-ORAC-value antioxidants, minerals, pepper extract, flavoring agents, coloring agents, and preservatives. The compositions can be in the form of beverages, tablets, capsules, powders, and the like.

Abstract: A composition and method are provided that are effective for reduction or elimination of the craving foods and other substances for which a patient wishes to reduce consumption or intake. The composition is a paste made of a binder, and non-binder ingredients of mustard, pepper and salt, and optionally a sweetener. The composition of the invention is administered on the tongue as a paste.

Abstract: The invention relates to the use, as an active ingredient, of at least one substance that promotes the deglycation of AGEs for preparing a composition, especially for limiting the presence of AGEs in a tissue. The invention particularly relates to the use of such a substance for preparing a composition intended to prevent and/or combat a reduction in flexibility and/or plasticity and/or elasticity and/or functionality of a tissue, and/or to prevent and/or combat the ageing of a tissue, by promoting the deglycation of AGEs in the tissue, said tissue preferably being the skin, or the tissue wall of a blood vessel or of an organ.

Abstract: A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water:methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination.

Abstract: A topical skin care composition comprising kakadu plum extract or acai berry extract, or a combination of both, is disclosed. The composition can include a high oxygen radical absorbance capacity (ORAC) value. The composition can improve the skin's visual appearance, physiological functions, clinical properties, and/or biophysical properties.

Abstract: Use of a composition comprising hyaluronic acid or a pharmaceutically acceptable salt thereof, in the manufacture of a topical medicament for antimicrobial treatment of the skin or mucosa.