Containing Or Obtained From Scutallaria (e.g., Scullcap, Etc.) Patents (Class 424/741)
  • Patent number: 11324793
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: May 10, 2022
    Assignee: YALE UNIVERSITY
    Inventors: Shwu-Huey Liu, Zaoli Jiang, Yung-Chi Cheng
  • Patent number: 11266670
    Abstract: The present disclosure discloses use of scutellarin in a medicament and a modulator for preventing or treating diseases, a medicament, and a modulator, which is related to the technical field of medicine. The present disclosure discloses use of scutellarin in the preparation of a medicament for preventing or treating a disease caused or mediated by interaction between TNF and TNFR2. The research in the present disclosure has shown that scutellarin is capable of selectively inhibiting TNF-induced death of WEHI-13VAR cells and significantly inhibiting TNF-induced proliferation of Tregs, accompanied with down-regulation of TNFR2 and Foxp3 expression in Tregs. This indicates that scutellarin can be used to treat or prevent relevant diseases caused or mediated by the interaction between TNF and TNFR2, and the present disclosure provides a new idea or means for preventing or treating relevant diseases caused or mediated by the interaction between TNF and TNFR2.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: March 8, 2022
    Assignee: University of Macau
    Inventors: Xin Chen, Ruixin Li, Shaokui Chen
  • Patent number: 11207367
    Abstract: Provided are a pharmaceutical composition for preventing an alcoholic hangover or alleviating a hangover, comprising a Longan arillus extract as an active ingredient, and a food composition for alleviating a hangover, comprising a Longan arillus extract.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: December 28, 2021
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok Yang, Na Young Bae, Huan Li, Joon Ki Kim
  • Patent number: 10722547
    Abstract: Compositions comprising extracts prepared from mixtures of the herbal plants Radix Bupleurum chinense DC (“B”), Rhizoma Corydalis yanhusuo WT Wang (“Y”), Caulis Polygonum multiflorum Thunb (“P”) and Flos Albizia julibrissin Durazz (“A”) are provided. The BYP, BYA, BPA, BY, BP, YP and BYPA extracts significantly decreased one or more of the effects of accelerated aging in mice exposed to D-galactose, including spatial memory deficit, and elevated oxidative stress marker malondialdehyde and pro-inflammatory cytokines TNF-alpha and IL-6 in the brain, indicating efficacy in reducing the damage of aging, and preventing and treating Alzheimer's disease and/or Parkinson's disease. Anxiolysis by the BYA, BPA, YPA, BA and PA extracts indicates efficacy for treating anxiety disorders, and the sedative effect of the BYA, YPA and PA extracts indicates efficacy for treating sleep disorders.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: July 28, 2020
    Assignee: PharmacoGenetics Limited
    Inventor: Hong Xue
  • Patent number: 10646530
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: May 12, 2020
    Assignee: YALE UNIVERSITY
    Inventors: Shwu-Huey Liu, Zaoli Jiang, Yung-Chi Cheng
  • Patent number: 10278998
    Abstract: An agonist mixture for activating a fast mucokinetic pathway is provided. An example method includes selecting agents for activating the complete mucokinetic pathway, determining proportions of the selected agents for activating the complete mucokinetic pathway in a mixture containing the selected agents, and administering the mixture to a user from a vaporizer, an inhaler, a mister, an e-cigarette, a sprayer, an atomizer, or a pressurized can. The method may further include administering to the user a mixture to be inhaled for nicotine withdrawal.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: May 7, 2019
    Inventor: Judy Colleen Henry
  • Patent number: 9333200
    Abstract: Provided herein are water-soluble prodrugs, compositions comprising such prodrugs, and related methods of making and administering the same. The prodrugs of the invention comprise a water-soluble polymer having three or more arms, at least three of which are typically covalently attached to an active agent, e.g., a small molecule. The conjugates of the invention provide an optimal balance of polymer size and structure for achieving improved drug loading, since the conjugates of the invention possess three or more active agents releasably attached to a multi-armed water-soluble polymer. The prodrugs of the invention are therapeutically effective, and exhibit improved properties in-vivo when compared to unmodified parent drug.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: May 10, 2016
    Assignee: Nektar Therapeutics
    Inventors: Xuan Zhao, Michael David Bentley, Zhongxu Ren, Tacey X. Viegas
  • Patent number: 9040102
    Abstract: This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: May 26, 2015
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun-Ok Yang, Na-Young Bae, Hak-Cheol Kwon, Sung-Kwon Chung, Myung-Sook Oh
  • Publication number: 20150132280
    Abstract: A human dietary supplement comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theacrine-containing supplement include improvement of at least one of mood, energy, focus, concentration or sexual desire or a reduction of at least one of anxiety or fatigue.
    Type: Application
    Filed: November 12, 2014
    Publication date: May 14, 2015
    Applicant: ORTHO-NUTRA, LLC
    Inventors: Hector L Lopez, Shawn Wells, Tim N. Ziegenfuss
  • Patent number: 8858953
    Abstract: An herbal composition and a method for treating cancer, especially for lung cancer, useful for enhancing the quality of life.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: October 14, 2014
    Inventor: Yu-Hwa Peter Sheng
  • Patent number: 8790724
    Abstract: The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-Ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions associated with the skin. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity in normal, aged and damaged dermal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the skin mediated by cyclooxygenase (COX) and lipoxygenase (LOX).
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: July 29, 2014
    Assignee: Unigen, Inc.
    Inventor: Qi Jia
  • Patent number: 8771761
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotriene, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: July 8, 2014
    Assignee: Unigen, Inc.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Publication number: 20140106013
    Abstract: A medical composition for inhibiting the growth of cancer stem cells is disclosed. The medical composition is prepared by mixing herbal medicines with water or alcohol, followed by heating and extraction to obtain a filtrate. One of the medical compositions according to the present invention includes: Coptis chinensis, Scutellaria baicalensis, Phellodendron amourense, Gardenia jasminoides, Radix Glycyrrhizae, and Atractylodes japonica.
    Type: Application
    Filed: December 23, 2013
    Publication date: April 17, 2014
    Applicant: National Taiwan Normal University
    Inventors: Hsiu-Mei HSIEH, Chen-Yu LEE
  • Patent number: 8658225
    Abstract: A nasal solution and method for treating nasal and sinus inflammation. The nasal solution includes vitamin C, an extract of scutellaria radix, an extract of eleutherococcus radix, an extract of chamomile, and a pharmaceutically acceptable carrier which is suitable for administering the vitamin C, the scutellaria radix extract; the eleutherococcus radix extract; and the chamomile to the nose of a patient. The method includes administering the nasal solution which suppresses early phase and late phase mediators of allergic mucosal disease in order to maintain long-term inhibition of nasal and sinus inflammation.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: February 25, 2014
    Assignee: ZNOVA, LLC
    Inventors: S. James Zinreich, Claus Bachert
  • Publication number: 20140037765
    Abstract: Provided is a formulation including a variety of Chinese herbs for the treatment of a disease, such as cancer, and side effects associated with the treatment of the disease.
    Type: Application
    Filed: October 2, 2013
    Publication date: February 6, 2014
    Applicant: LIFE BIOTECH MEDICAL RESEARCH LTD
    Inventor: Yair N. MAIMON
  • Patent number: 8637092
    Abstract: The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of Radix Trichosanthis (Tianhuafen), 10-30 weight parts of Radix Bupleuri (Chaihu), 3-15 weight parts of Fructus Aurantii Immaturus (Zhishi), 1-6 weight parts of Radix et Rhizoma Rhei (Dahuang), 1-12 weight parts of Rhizoma Pinelliae (Banxia), 3-15 weight parts of Radix Scutellariae (Huangqin), 1-12 weight parts of Rhizoma Coptidis (Huanglian), 3-15 weight parts of Radix Paeoniae Alba (Baishao) and 5-20 weight parts of Fructus Mume (Wumei), and optionally comprises pharmaceutically acceptable excipient. Also, the pharmaceutical composition of the present invention can further comprise Fructus Crataegi (Shanzha). Additionally, the present invention discloses four methods for preparing the pharmaceutical composition.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: January 28, 2014
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xiaolin Tong, Yonghong Zhu, Shuiping Zhou, Xiuhui E, Shuangming Wang, Zhongting Xia
  • Publication number: 20130323335
    Abstract: A composition comprising a Sanguisorbae officinalis plant extract and at least one additional plant extract selected from the group consisting of an Ailanthus altissima plant extract, a Galla rhois gallnut plant extract, a Glycyrrhiza Glabra plant extract, a Rheum palmatum plant extract and a Scutellaria baicalensis plant extract is disclosed. Compositions comprising Ailanthus altissima plant extract or Ailanthone are also disclosed.
    Type: Application
    Filed: December 28, 2011
    Publication date: December 5, 2013
    Inventors: Sharon Rozenblat, DaiHyun Jung, SangHyun Moh, SuJung Kim, JungHun Lee
  • Patent number: 8597690
    Abstract: A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising 1.5 parts by weight powdered fennel, 2.0 parts by weight powdered rhubarb, 1.0 part by weight powdered glycyrrhiza, 2.0 parts by weight powdered phellodendron bark, 1.0 part by weight powdered zedoary, 1.5 parts by weight powdered picrasma wood, 1.0 part by weight powdered matricaria chamomilla, 1.5 parts by weight powdered geranium herb, 1.0 part by weight powdered ginseng, 1.5 parts by weight powdered citrus unshiu peel, 1.0 part by weight powdered scutellaria root, 1.0 part by weight powdered magnolia bark, 2.0 parts by weight powdered oyster shell, 1.0 part by weight powdered cyperus rhizome, 2.0 parts by weight powdered platycodon root, 2.0 parts by weight powdered melia azedarach, 1.0 part by weight powdered cnidium rhizome, 2.0 parts by weight sodium bicarbonate and 4.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: December 3, 2013
    Assignee: Nakamori Pharmaceutical Co., Ltd.
    Inventor: Toshio Nakamori
  • Patent number: 8574636
    Abstract: Provided is a formulation including a variety of Chinese herbs for the treatment of a disease, such as cancer, and side effects associated with the treatment of the disease.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: November 5, 2013
    Assignee: Lifebiotic Medical Research Ltd
    Inventor: Yair N. Maimon
  • Publication number: 20130236576
    Abstract: The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises Forsythiae fructus, Menthae Herba, Gardeniae Fructus, Scutellariae Radix, Lophatheri Folium, Glycyrrhizae Radix, Rhei Rhizoma, Na2SO4, and Atractylodis Rhizoma. The residual examples are described herein.
    Type: Application
    Filed: April 30, 2013
    Publication date: September 12, 2013
    Inventor: Chen-Yu LEE
  • Publication number: 20130136811
    Abstract: Compositions containing four-herb extract combination or Wogonin are useful in methods for the reduction of pain. A four-herb combination is used to treat pain as well as reduce or prevent epileptic seizures.
    Type: Application
    Filed: May 26, 2011
    Publication date: May 30, 2013
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Steven C. Schachter
  • Publication number: 20130122035
    Abstract: An herbal composition and a method for treating cancer, especially for lung cancer, useful for enhancing the quality of life.
    Type: Application
    Filed: May 8, 2012
    Publication date: May 16, 2013
    Inventor: Yu-Hwa Peter Sheng
  • Publication number: 20130064910
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
    Type: Application
    Filed: August 15, 2012
    Publication date: March 14, 2013
    Applicant: Unigen, Inc.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Publication number: 20130011499
    Abstract: The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises Forsythiae fructus, Menthae Herba, Gardeniae Fructus, Scutellariae Radix, Lophatheri Folium, Glycyrrhizae Radix, Rhei Rhizoma, Na2SO4, and Atractylodis Rhizoma. The residual examples are described herein.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Inventor: Chen-Yu LEE
  • Publication number: 20130004533
    Abstract: An agent comprising one or more components selected from among cowberry derivatives, mangosteen derivatives, scutellaria root derivatives, inositol and inositol phosphate, as an active ingredient, is a novel agent that can effectively promote production of platelet-derived growth factor-BB (PDGF-BB), which contributes to production of mesenchymal stem cells and stabilization of stem cells.
    Type: Application
    Filed: July 1, 2011
    Publication date: January 3, 2013
    Inventors: Tsutomu Soma, Masato IIno, Haruyo Yamanishi
  • Publication number: 20120244135
    Abstract: Use of at least one extract from the Anogeissus genus for treating human skin by producing fibrillin and thereby increasing skin elasticity.
    Type: Application
    Filed: September 19, 2011
    Publication date: September 27, 2012
    Inventors: Susan M. Daly, Liovo Declorcq
  • Patent number: 8247007
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: August 21, 2012
    Assignee: Unigen, Inc.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Patent number: 8241679
    Abstract: The present invention relates to a composition comprising an extract of crude drug complex comprising Panax ginseng C. A. Meyer, Acanthopanax senticosus HARMS, Angelica sinensis DIELS, Scutellaria baicalensis GEORGI, prevention and treatment of stroke and neurodegenerative diseases such apoplexy, Alzheimer's disease (AD), Parkinson's disease (PD), Pick's disease, Creutzfeldt-Jakob disease and senile dementia.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: August 14, 2012
    Assignee: Neumed Inc.
    Inventors: Hocheol Kim, Young Min Boo
  • Patent number: 8197868
    Abstract: An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the G1 phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: June 12, 2012
    Assignee: BioNovo, Inc.
    Inventor: Isaac Cohen
  • Publication number: 20120009282
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of cancer by administering the herbal composition PHY906 in combination with one or more chemotherapeutic compounds to a mammal undergoing such chemotherapy.
    Type: Application
    Filed: June 10, 2009
    Publication date: January 12, 2012
    Applicants: PHYTOCEUTICA, INC., YALE UNIVERSITY
    Inventors: Yung-Chi Cheng, Shwu-Huey Liu, Zaoli Jiang, Robert Tilton
  • Publication number: 20110318435
    Abstract: This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins.
    Type: Application
    Filed: February 22, 2011
    Publication date: December 29, 2011
    Applicant: Korea Institute of Science and Technology
    Inventors: Hyun-Ok YANG, Na-Young BAE, Hak-Cheol KWON, Sung-Kwon CHUNG, Myung-Sook OH
  • Publication number: 20110236511
    Abstract: Provided is a formulation including a variety of Chinese herbs for the treatment of a disease, such as cancer, and side effects associated with the treatment of the disease.
    Type: Application
    Filed: September 24, 2009
    Publication date: September 29, 2011
    Applicant: LIFE BIOTECH MEDICAL RESEARCH LTD
    Inventor: Yair N. Maimon
  • Publication number: 20110183015
    Abstract: A medical composition for inhibiting the growth of cancer stem cells is disclosed. The medical composition is prepared by mixing herbal medicines with water or alcohol, followed by heating and extraction to obtain a filtrate. One of the medical compositions according to the present invention includes: Coptis chinensis, Scutellaria baicalensis, Phellodendron amourense, Gardenia jasminoides, Radix Glycyrrhizae, and Atractylodes japonica.
    Type: Application
    Filed: November 9, 2010
    Publication date: July 28, 2011
    Applicants: National Taiwan Normal University
    Inventors: Hsiu-Mei Hsieh, Chen-Yu Lee
  • Publication number: 20110171329
    Abstract: A method for treating neural damage with a composition prepared from roots of bupleurum and scutellaria.
    Type: Application
    Filed: January 24, 2011
    Publication date: July 14, 2011
    Inventors: Henrich Cheng, May-Jywan Tsai
  • Publication number: 20110020478
    Abstract: A method for treating neural damage with a composition prepared from roots of bupleurum and scutellaria.
    Type: Application
    Filed: March 19, 2010
    Publication date: January 27, 2011
    Inventors: Henrich Cheng, May-Jywan Tsai
  • Publication number: 20100255129
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.
    Type: Application
    Filed: February 14, 2008
    Publication date: October 7, 2010
    Applicants: YALE UNIVERSITY, PHYTOCEUTICA, INC.
    Inventors: Shwu-Huey Liu, Zaoli Jiang, Yung-Chi Cheng
  • Patent number: 7771758
    Abstract: An extract of Scutellaria lateriflora L. having a content of flavonoids, calculated as the sum of baicalein, scutellarin, dihydrobaicalin, ikonnikoswide I, lateriflorin, baicalein, lateriflorein and wogonin, of at least 18% by weight. A method of obtaining such an extract includes combining dried Scutellaria lateriflora L. plant material with a solvent.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: August 10, 2010
    Assignee: Tom's of Maine
    Inventors: Stefen Gafner, Chantal Bergeron, Fiona Elizabeth Russell
  • Publication number: 20100166892
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.
    Type: Application
    Filed: February 14, 2008
    Publication date: July 1, 2010
    Applicants: YALE UNIVERSITY, PHYTOCEUTICA, INC.
    Inventors: Shwu-Huey Liu, Zaoli Jiang, Yung-Chi Cheng
  • Publication number: 20100143511
    Abstract: An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the G1 phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.
    Type: Application
    Filed: January 21, 2010
    Publication date: June 10, 2010
    Applicant: Bionovo, Inc.
    Inventor: Isaac Cohen
  • Patent number: 7648718
    Abstract: The present invention relates to a composition comprising an extract of crude drug complex comprising Panax ginseng C. A. Meyer, Acanthopanax senticosus HARMS, Angelica sinensis DIELS, Scutellaria baicalensis GEORGI, prevention and treatment of stroke and neurodegenerative diseases such apoplexy, Alzheimer's disease (AD), Parkinson's disease (PD), Pick's disease, Creutzfeldt-Jakob disease and senile dementia.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: January 19, 2010
    Assignee: University-Industry Cooperation Group of Kyung Hee University
    Inventors: Hocheol Kim, Young Min Boo
  • Patent number: 7615239
    Abstract: Technical Field: Tea Technical Problem: To provide a drinkable tea having a high therapeutic effect against atopic dermatitis. Means for Solving: It is characterized in that it contains extracts drawn from one, two or more medicinal herbs selected from the group consisting of Lightyellow Sophora Root, Isatis Leaf, and Terminalia Fruit. Atopic dermatitis can be cured by improving allergic constitution from the inside of body owing to antibacterial effect and antiviral effect of Lightyellow Sophora Root, Isatis Leaf and Terminalia Fruit, antiallergic effect of Lightyellow Sophora Root and Isatis Leaf, and intestinal mucosal protecting effect of Terminalia Fruit, or by a synergistic effect of them.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: November 10, 2009
    Inventors: Tetsuo Santo, Songhua Li, Ruwei Wang, Sumio Iwasaki
  • Publication number: 20090130118
    Abstract: An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the G1 phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.
    Type: Application
    Filed: November 19, 2008
    Publication date: May 21, 2009
    Applicant: BIONOVO, INC.
    Inventor: Isaac Cohen
  • Publication number: 20090130237
    Abstract: An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the G1 phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.
    Type: Application
    Filed: November 19, 2008
    Publication date: May 21, 2009
    Applicant: BIONOVO, INC.
    Inventor: Isaac Cohen
  • Publication number: 20090104174
    Abstract: The present invention relates to methods and compositions for reducing the appearance of dynamic facial wrinkles by administering oral and/or topical compositions comprising therapeutically-effective amounts of extracts of one or more relaxing herbal agents (“RHAs”) alone or in combination with one or more extracts of an edible solanaceous glycoalkaloid-containing plant (“ESGP”) or an edible glycoalkaloid-containing fungus (“EGF”) selected from plant species in the genus Solanum and mushrooms. RHAs are selected from the group consisting of extracts of Q. amara, E. angustifolia, P. oleracea, M. dubia, P. orientalis and A. muscaria and plant species from the genus Valeriana, Passiflora, Verbascum, Scutellaria, Cypripedium, Magnolia, Atriplex and Symphytum. Additionally, the methods of the present invention may comprise exfoliating the skin, preferably with at least one acid protease enzyme.
    Type: Application
    Filed: June 25, 2008
    Publication date: April 23, 2009
    Inventor: Walter P. Smith
  • Publication number: 20090053335
    Abstract: The invention provides a herbal composition for the inhibition of HIV, comprising an organic extract of Hedyotis diffusa (Oldenlandia diffusa), an organic solvent extract of Scutellaria barbata or Scutellaria rivularis, an organic solvent extract of Lonicera japonica or Lonicera confusato, an organic solvent extract of Prunella vulgari and an organi solvent extract of Solanum nigrum.
    Type: Application
    Filed: April 13, 2007
    Publication date: February 26, 2009
    Inventor: Chih-Hui Lin
  • Publication number: 20090047310
    Abstract: Use of an extract of Griffonia, in particular of Griffonia simplicifolia, in a cosmetic or dermatological preparation for attenuating the pigmentation of the skin and of superficial body growths. This cosmetic or dermatological preparation may also contain any of the following products: at least one other active depigmenting product, at least one substance for filtering or blocking B and/or A ultraviolet radiation, at least one anti-inflammatory product, at least one agent encouraging flaking. It contains from 0.05 to 20% by weight of an extract of Griffonia simplicifolia.
    Type: Application
    Filed: May 24, 2006
    Publication date: February 19, 2009
    Inventor: Alain Meybeck
  • Patent number: 7402311
    Abstract: A composition and a method for treatment of urinary tract dysfunction and, particularly, non-bacterial cystitis and, even more particularly, non-bacterial chronic interstitial cystitis. The composition primarily relies upon the use of a bioflavonoid and, particularly, that bioflavonoid known as quercetin. The quercetin is mixed with a proteolytic digestive enzyme protease, such as bromelin and papain, as the primary active ingredients. However, the composition may optionally and beneficially include other cystitis affecting agents, such as cranberry, as well as some other active and non-active ingredients.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: July 22, 2008
    Inventors: Floyd A. Katske, Daniel Shoskes
  • Publication number: 20080031891
    Abstract: Described herein are compositions derived from natural products useful in reducing or preventing pain in a subject and methods of use thereof.
    Type: Application
    Filed: December 20, 2006
    Publication date: February 7, 2008
    Inventor: Ronald Lewis
  • Patent number: 7264828
    Abstract: The process of extracting small molecular ingredients from biological materials under super high pressure is a process which makes use of super high pressure to extract small molecular active ingredients from biological materials, especially natural products, which mainly consists of extracting the mixture of solid raw material and extraction solvent under increased pressure. Said process comprises the following steps: the step of pretreatment, crash and formulation; the step of closure, charging the formulated mixture of raw material and extraction solvent into high pressure container, then closing the high pressure container; the step of increasing pressure, increasing the pressure of the high pressure container from 100 Mpa to the predefined pressure of 1000 Mpa; the step of holding pressure, holding the predefined pressure for 3-30 minutes; the step of releasing pressure, releasing the pressure of the high pressure container to normal pressure, removing the mixture.
    Type: Grant
    Filed: December 30, 2002
    Date of Patent: September 4, 2007
    Inventor: Shouqin Zhang
  • Publication number: 20070196348
    Abstract: Supplemental compositions, and methods for administering same to a user, are provided for promoting a restful night's sleep by speedily inducing a person to fall asleep and to maintain sleep, as well as alleviating minor aches and pains so as to further improve the quality of a person sleep. The supplemental composition may include at least an extract of Valerian Root, an extract of Willow Bark and Melatonin or a derivative thereof. The supplemental composition may be provided for consumption at least one time daily, e.g., prior to sleep.
    Type: Application
    Filed: July 14, 2006
    Publication date: August 23, 2007
    Inventors: Paul T. Gardiner, Marvin A. Heuer, Shan Chaudhuri, Kenneth Clement