Containing Or Obtained From Scutallaria (e.g., Scullcap, Etc.) Patents (Class 424/741)
  • Patent number: 7255884
    Abstract: A pharmaceutical preparation of Chinese herbal medicines for tonifying the kidneys and alleviating asthma is disclosed herein. The Chinese herbal medicines include Perilla Frutescens, Prunus Armeniaca, Glycyrrhiza Uralensis, Scutellaria Baicalensis, Coptis Chinesis, Tusilago Farfara, Stemona Sessilifolia, Fritillaria Cirrhosa, Pheretima Aspergillum, Psoralaea Corylifolia, Codonopsis Pilosula, Hordeum Vulgara, Massa Fermentata Medicalis, Schisandra Chinesis, and Gypsum. The preparation is used to treat thousands of patients suffering from asthma with an effective rate of 93%. The present preparation can relieve cough, expel phlegm, resist airway allergic inflammation reaction, improve pulmonary function, partial pressure of the oxygen in the blood, increase CD2, CD4, CD4/CD8, reduce IgE in blood, increase CAMP, reduce CGMP, stabilize mast cells, and inhibit the release of histamine, which make it capable of stopping an asthma attack.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: August 14, 2007
    Inventor: Hongfen Li
  • Patent number: 7097864
    Abstract: The present invention relates to a transdermal pain composition consisting of astragalus extract, cat's claw extract, mistletoe extract, sheep sorrell extract, green tea extract, capsaicin, nettle leaf extract, skull cap extract, l-glutamine and fat soluble ascorbyl palmitate in the form of vitamin c.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: August 29, 2006
    Inventor: Michael D. Farley
  • Patent number: 7045158
    Abstract: The present invention relates to an improved extract of Scutellaria lateriflora, a method of preparing the same, and a pharmaceutical composition prepared from the present extract suitable for treating anxiety, insomnia, convulsions, muscle tension and spasm, and related manifestations and disorders in humans and other mammals. The invention also relates to an improved method of treating anxiety, insomnia, convulsions, muscle tension and spasm, and related manifestations and disorders in humans and other mammals by administering the improved extract of Scutellaria lateriflora.
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: May 16, 2006
    Inventors: Philip E. Wolfson, David Ludwig Hoffmann
  • Patent number: 6855346
    Abstract: The present invention provides a method for treating patients with liver diseases by co-administrating a pharmaceutical composition and lamivudine to the patients. The pharmaceutical composition is a herbal mixture which contains, as the core ingredients, the aqueous extracts of the entire plant of Herba Hedyotidis diffusae, the rhizome of Rhizoma Bistortae, the rhizome of Rhizoma Polygoni Cuspidati, and the ripe fruit of Fructus Schisandrae. The present invention also provides methods for preventing a relapse of hepatitis in patients after the lamivudine treatment has been discontinued and for suppressing the development of lamivudine drug resistance in patients by providing the lamivudine-treated patients with the pharmaceutical composition of the present invention.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: February 15, 2005
    Inventor: Tzu-Sheng Wu
  • Publication number: 20040265402
    Abstract: Pharmaceutical compositions for treating immunological disorders and the preparing method of the same are disclosed, which include alcohol extracts of Radix Dioscorea, Rhizoma Alismatis, Poria cocos (schw) Wolf, and Scutellaria Baicalensis. The compositions are manufactured by novel procedures consisting of decocting using specific concentration ranges of alcohol, filtering, regulating pH value, purifying, concentrating, proportionally mixing, and making a granule powder from lyophilized extract. This invention used both in vitro and in vivo assays to evaluate therapeutic effects of specific combination of herbal plant extracts. The combination of herbal extracts has been able to maximize the anti-inflammatory activity and regulate the secretion of cytokines such as eotaxin and IL-4.
    Type: Application
    Filed: June 30, 2003
    Publication date: December 30, 2004
    Applicant: Industrial Technology Research Institute
    Inventors: Rong-Ming Lyu, I-Hong Pan, Jir-mehng Lo, Sue-Fen Jiang, Sheau-Ni Su, Nai-Yun Hsu, Shih Cheng Shen, Hsin-Chieh Wu, Lain-Tze Lee, Yih-Loong Lai, Jaw-Ji Tsai
  • Publication number: 20040253328
    Abstract: An anti-atypical pneumonia decoction where a Chinese medicinal formula comprises the following medicinal materials: scutellaria root 0.5˜10 weight parts, gardenia 0.5˜10 weight parts, honeysuckle flower 0.5˜10 weight parts, weeping forsythia 0.5˜10 weight parts, dried rehmannia root 0.5˜10 weight parts, gypsum 0.5˜10 weight parts, flos chrysanthemi indici 0.5˜10 weight parts, basket fem 0.5˜10 weight parts, balloonflower root 0.5˜10 weight parts, mint 0.5˜10 weight parts, arctium fruit 0.5˜10 weight parts, and liquorice 0.5˜10 weight parts. Those medicinal materials were decocted with water to obtain the anti-atypical pneumonia decoction. The anti-atypical pneumonia decoction of the invention has satisfactory effect for preventing and treating atypical pneumonia or suspected atypical pneumonia.
    Type: Application
    Filed: July 21, 2003
    Publication date: December 16, 2004
    Inventors: Xin Yuan Hu, XiMing Wang, Jingshu Xue
  • Publication number: 20040234627
    Abstract: The present invention provides an herbal pharmaceutical compositions comprising the root of scutellaria, the rhizome of coptis, the root and rhizome of rhubarb, and the dry powders of the root of ginseng (or American ginseng) or the rhizome of ginger. The herbal pharmaceutical compositions are effective in preventing patients from developing or treating patients with cardiovascular diseases, which include, but are not limited to, hypertension, coronary heart disease, cerebrovascular disease, peripheral vascular disease, heart failure, rheumatic heart disease, congenital heart disease, and cardiomyopathies. The present invention also provides methods for preparing and using the herbal pharmaceutical compositions.
    Type: Application
    Filed: June 25, 2004
    Publication date: November 25, 2004
    Applicants: SunTen Pharmaceutical Co., Ltd.
    Inventors: Shuenn-Jyi Sheu, Chung Guang Shen
  • Patent number: 6814985
    Abstract: The present invention relates generally to a composition for the treatment or prophylaxis of allergic and inflammatory reactions such as but not limited to Type I hypersensitivity reactions in mammals. More particularly, the present invention is directed to compositions comprising herbs or extracts of herbs or botanical or horticultural equivalents of the herbs or chemical or functional equivalents of the herbal extracts useful in the treatment or prophylaxis of allergic and inflammatory reactions such as but not limited to respiratory disorders. The present invention further contemplates a method of treating allergic and inflammatory reactions in mammals and in particular Type I hypersensitivity disorders and even more particularly respiratory disorders by the administration of a herbal composition or its chemical or functional equivalent.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: November 9, 2004
    Assignee: G & W Aust Pty. Ltd.
    Inventor: Guorang Hu
  • Patent number: 6787165
    Abstract: The invention provides a new formulation of the composition comprising Flos Lonicerae Fructus Forsythiae and Radix Scutellariae. This invention also provides a method for identification with HPLC and the characteristic peaks of the compositions of said composition. The composition possesses antiviral effective, namely, inhibition of influenza virus, parainfluenza virus, herpes I virus and herpes II virus. The invention refers to a method for preparation and control of the active components of Flos Lonicerae Fructus Forsythiae and Radix Scutellariae for its biological activity. The invention also provides a unique raw materials and intermediate formulation.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: September 7, 2004
    Assignee: National Engineering Research Center for Traditional Chinese Medicine
    Inventors: Ping Niang Shen, Ke Feng Ruan, Yu Lan Wang, Wei Yu, Wen Qing Zhang, Xiao Kun Hong, Xin Hong Wang
  • Publication number: 20040109906
    Abstract: An extract of Scutellaria lateriflora L. having a content of flavonoids, calculated as the sum of baicalin, scutellarin, dihydrobaicalin, ikonnikoside I, lateriflorin, baicalein, lateriflorein and wogonin, of at least 18% by weight. A method of obtaining such an extract includes combining dried Scutellaria lateriflora L. plant material with a solvent.
    Type: Application
    Filed: September 5, 2003
    Publication date: June 10, 2004
    Inventors: Stefan Gafner, Chantal Bergeron, Fiona Elizabeth Russell
  • Publication number: 20040109904
    Abstract: A unique class of anti-neoplastic compositions are described. The compositions contain certain Chinese medicinal herbs: Panax ginsing, Poria cocos, Atractylodes macrocephala, Angelic sinensis, Astragalus membranaceus, Curcuma zedoaria, Scutellaria baicalensis, Coptis chinenisis, Glycyrrhiza uralenisis, Crataegus pinatifida, Hordeum vulgare, Schisandra chinensis, Hedyotis diffusa, Ophiophogon japonicus, and Lobelia chinesis lour. Extensive testing indicates an effective treatment rate of 69.7% and 84.3% when used in combination with radiotherapy or chemotherapy. The animal trials conducted demonstrate that the anti-neoplastic compositions increase the activity of NK cells, and reduce and prevent metastasis of tumors under stress conditions.
    Type: Application
    Filed: January 29, 2004
    Publication date: June 10, 2004
    Inventor: Hongfen Li
  • Patent number: 6740343
    Abstract: The present invention relates to an improved extract of Scutellaria lateriflora, a method of preparing the same, and a pharmaceutical composition prepared from the present extract suitable for treating anxiety, insomnia, convulsions, muscle tension and spasm, and related manifestations and disorders in humans and other mammals. The invention also relates to an improved method of treating anxiety, insomnia, convulsions, muscle tension and spasm, and related manifestations and disorders in humans and other mammals by administering the improved extract of Scutellaria lateriflora.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: May 25, 2004
    Assignee: Phytos, Inc.
    Inventors: Philip E. Wolfson, David Ludwig Hoffmann
  • Publication number: 20040071796
    Abstract: The present invention discloses a pharmaceutical preparation of Chinese herbal medicines which consists of Chinese herbal medicines for tonifying kidney and antiasthma, wherein the Chinese herbal medicines are Perilla Frutescens, Prunus Armeniaca, Glycyrrhiza Uralensis, Scutellaria Baicalensis, Coptis Chinesis, Tusilago Farfara, Stemona Sessilifolia, Fritllaria Cirrhosa, Pheretima Aspergillum, Psoralea Corylifolia, Codonopsis Pilosula, Hordeum Vulgara, Massa Fermentata Medicalis, Schisandra Chinensis, Gypsum. The preparation has been used in China for 20 years, and in Israel for more than 5 years. It has been used to treat thousands of patients suffering from asthma with an effective rate of 93%.
    Type: Application
    Filed: October 2, 2003
    Publication date: April 15, 2004
    Inventor: Hongfen Li
  • Publication number: 20030224074
    Abstract: Disclosed is a composition for protecting nerve cells, promoting nerve cell growth and regenerating nerve cells comprising a Scutellaria Radix extract. The composition has excellent protective effects against apoptosis of neuronal stem cells and differentiated nerve cells, a positive effect of inducing the regeneration of nerve cells, a regenerative effect on neurites, a neuroregenerative effect on brain nerves and peripheral nerves, a reformation effect on neuromuscular junctions, and a protective effect agaisnt apoptosis of nerve cells and a neuroregenerative effect in animals suffering from dementia and brain ischemia. Therefore, the composition can be used as a therapeutic agent for the prevention and treatment of nerodegenerative diseases, ischemic nervous diseases or nerve injuries, and for the improvement of learning capability.
    Type: Application
    Filed: March 14, 2003
    Publication date: December 4, 2003
    Applicant: EUGENBIO INC.
    Inventors: Byung-Kil Choe, Yun-Hee Kim, Soo-Kyung Kim, Jung-Su Lim, Hyo-Sup Kim, Dae-Sung Park, Chi-Young Chang
  • Publication number: 20030211180
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of drugs, including those used in the treatment of disease, especially viral infections and neoplasms of cancer. This invention provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a person undergoing such chemotherapy.
    Type: Application
    Filed: December 30, 2002
    Publication date: November 13, 2003
    Inventors: Yung-Chi Cheng, Shwu-Huey Liu
  • Patent number: 6641846
    Abstract: The invention is related to a pharmaceutical composition with its main effects against Type I Allergy and the process thereof. The composition mainly comprises the following raw materials by weight ratio: 30˜60 parts of Fructus Jujubae, 12˜55 parts of Radix Astragali, 8˜15 parts of Radix glycyrrhizae, 6˜12 parts of Ramulus cinnamomi, 6˜12 parts of Ginger and 4˜8 parts of Green tea.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: November 4, 2003
    Assignee: Tianjin Yanling Health Food Co.
    Inventors: Zuoguang Zhang, Yanling Fu
  • Publication number: 20030190379
    Abstract: A salve for application to a burn wound to support healing the wound including a mixture of healing agents which consists of Radix Scutellariae, Cortex Phellodendri, Rhizoma Coptidis mixed according to the ratio by weight of 1:1:1 The mixture is ground to pass through a 180 mesh screen. A carrier is formulated by dissolving beeswax in sesame oil according to the ratio of 10 grams of beeswax in 100 milliliters of sesame oil. The ground mixture is added to the sesame oil containing bee's wax according to the ratio of 10.7 grams of mixture to 100 milliliters of oil so as to form a salve. A preferred method of treatment is to spread the salve on a gauze pad and then to lay the pad over the wound.
    Type: Application
    Filed: April 3, 2002
    Publication date: October 9, 2003
    Inventor: Du Ben Hai
  • Publication number: 20030147969
    Abstract: The present invention provides a method for treating patients with liver diseases by co-administrating a pharmaceutical composition and lamivudine to the patients. The pharmaceutical composition is a herbal mixture which contains, as the core ingredients, the aqueous extracts of the entire plant of Herba Hedyotidis diffusae, the rhizome of Rhizoma Bistortae, the rhizome of Rhizoma Polygoni Cuspidati, and the ripe fruit of Fructus Schisandrae. The present invention also provides methods for preventing a relapse of hepatitis in patients after the lamivudine treatment has been discontinued and for suppressing the development of lamivudine drug resistance in patients by providing the lamivudine-treated patients with the pharmaceutical composition of the present invention.
    Type: Application
    Filed: July 11, 2002
    Publication date: August 7, 2003
    Inventor: Tzu-Sheng Wu
  • Publication number: 20030086879
    Abstract: An immunopotentiator for preventing ultraviolet light-induced skin immunosuppression or a drug against ultraviolet light-induced skin immunosuppression which contains glutathione or Scutellaria root extract. Also, an immunopotentiator or a drug against immunosuppression which contains linden extract, clove extract, Geranium herb extract or rosemary extract. They can prevent a reduction of immune functions due to ultraviolet light.
    Type: Application
    Filed: May 7, 2002
    Publication date: May 8, 2003
    Applicant: Shiseido Co., Ltd.
    Inventors: Eiichiro Yagi, Masako Naganuma, Ichiro Iwai, Masato Hatao, Kenji Yamaguchi, Genji Wada
  • Patent number: 6548088
    Abstract: A medicinal preparation includes a number of medicinal materials having asari radix, fructus cnidii, nelumbo nucifera gaertner, ginseng radix, angelica sinensis radix, scutellaria baicalensis, phellodendron amurense radix, evodiae fructus, and saussureae radix, and grounded into powder, and blended with water to form a pasty material which may be refrigerated and dried to form a crystallized material. A number of substrates may then be mixed with the pasty material or the crystallized material, and rotated to form a gluey material for being used by the users.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: April 15, 2003
    Inventor: Bih Cheng Chen
  • Publication number: 20030054050
    Abstract: The present invention relates to an improved extract of Scutellaria lateriflora, a method of preparing the same, and a pharmaceutical composition prepared from the present extract suitable for treating anxiety, insomnia, convulsions, muscle tension and spasm, and related manifestations and disorders in humans and other mammals. The invention also relates to an improved method of treating anxiety, insomnia, convulsions, muscle tension and spasm, and related manifestations and disorders in humans and other mammals by administering the improved extract of Scutellaria lateriflora.
    Type: Application
    Filed: September 17, 2002
    Publication date: March 20, 2003
    Inventors: Philip E. Wolfson, David Ludwig Hoffmann
  • Patent number: 6524627
    Abstract: This invention relates to a pharmaceutical composition comprising Platycodi Radix, Scutellariae Radix, Ponciri Fructus, Schizonepetae Herba, Bupleuri Radix, Angelicae dahuricae Radix, Paeoniae Radix alba, Cnidii Rhizoma, Angelicae gigantis Radix, Ledebouriellae Radix, Forsythiae Fructus, Glycyrrhizae Radix, Lonicerae Flos, Taraxaci Herba, Trichosanthis Radix, Ulmi Cortex Radicis, Astragali Radix, Atractylodis Rhizoma alba, Rehmanniae Rhizoma, Zanthoxyli Fructus, Magnoliae Flos, Xanthii Fructus, Mori Cortex Radicis, Pinelliae Tuber, Cimicifugae Rhizoma, Puerariae Radix and Menthae Herba as the active ingredients for preventing and/or treating acute and/or chronic allergic nasal diseases (including chronic paranasal sinusitis), allergic dermatitis, allergic otitis media (including recurrent otitis media with effusions), allergic conjunctivitis, allergic asthma, etc., and to a method for preparation thereof.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: February 25, 2003
    Assignees: Daehan Biolink Co., Ltd., Biomedpark Co., Ltd.
    Inventors: Hyung-Min Kim, Chul-Ho Jang, Woo-Jun Hwang, Eun-Jeung Park
  • Publication number: 20020136787
    Abstract: A novel powder composition comprised of a skin irritation reducing agent comprising 1-Carboxy-N,N,N-trimethylmethanaminium hydroxide inner salt, scutellaria baicalensis extract, bisabolol, or mixtures thereof. Also provided is a method for treating prickly heat comprised of topically applying an effective amount of the powder to a desired area.
    Type: Application
    Filed: February 22, 2002
    Publication date: September 26, 2002
    Inventors: Attaya Nitikhunkasem, Alain V. Khaiat, John Hopkins
  • Publication number: 20020122835
    Abstract: Compositions comprising zinc, magnesium and vitamin B6 and optionally theanine are effective for enhancing muscle and tissue recovery during sleep, following intense physical exercise.
    Type: Application
    Filed: March 1, 2001
    Publication date: September 5, 2002
    Inventors: Luke R. Bucci, Alan Shugarman, Jeffrey A. Felliciano, Marta Draper Rodriguez
  • Publication number: 20020094350
    Abstract: This invention provides processes for isolating pharmaceutically active fractions from the mushroom Scutellariae barbatae designated herein as ESBa, ESBb and ASB03. This invention provides a method for inhibiting the growth of endothelial cells by delivering to the cells a growth inhibitory amount of a fraction of this invention. This invention also provides a method of inhibiting vascularization in a tissue by delivering to the tissue an anti-vascularization amount of a fraction of this invention. Methods of treating various diseases, including cancer, are also provided herein.
    Type: Application
    Filed: December 12, 2001
    Publication date: July 18, 2002
    Inventor: Kin-Ping Wong
  • Publication number: 20020076446
    Abstract: The present invention provides a herbal pharmaceutical composition for treating patients with liver diseases and/or HIV. The composition contains fifteen (15) ingredients, which are diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, milkvetch root, barbary wolfberry fruit, sanqi, red ginseng, figwort root, Chinese magnoliavine fruit, turmeric root-tuber, hawthorn fruit, and Chinese angelica. Among the fifteen (15) ingredients, diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit are the required herbs which contribute to the efficacy of the pharmaceutical composition.
    Type: Application
    Filed: July 18, 2001
    Publication date: June 20, 2002
    Inventor: Tzu-Sheng Wu
  • Patent number: 6391346
    Abstract: An orally administered composition capable of reducing inflammation in animals, preferably humans, while promoting sleep for such animals, contains a therapeutically effective amount of a post-supercritical carbon dioxide hydroalcoholic extract of ginger, therapeutically effective amounts of supercritical carbon dioxide extracts of hops, chamomile, ginger, valerian and melissa; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellaria baicalensis, chamomile and hops. The composition is preferably orally administered on a daily basis for at least about 4 weeks.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: May 21, 2002
    Inventors: Thomas Newmark, Paul Schulick
  • Patent number: 6358540
    Abstract: A method for treating tinnitus comprising the step of administering to a subject requiring such treatment a therapeutically effective amount of an herbal composition comprising Radix Puerariae, Radix Platycodi Grandiflori, Radix Angelicae Dahuricae, Semen Coicis Lachryma-jobi, Rhizoma Zigiberis Officinalis Recens, Radix Ligustici Chuanxiong, Radix Paeoniae Lactiflorae, Folium Perillae Frutescentis, Flos Magnoliae, Herba cum Radice Asari, Ramulus Cinnamomi Cassiae, Radix Scutellariae Baicalensis, and Radix Glycyrrhizae Uralensis.
    Type: Grant
    Filed: November 7, 2000
    Date of Patent: March 19, 2002
    Inventors: Stanley T. Ozog, III, Delmar S. Neville, II
  • Patent number: 6348204
    Abstract: A cosmetic or dermatological composition, comprising: in combination, at least one extract of mulberry or an active substance isolated from the extract, at least one extract of skullcap or an active substance isolated from the extract and at least one salicylic acid derivative or salt thereof.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: February 19, 2002
    Assignee: L'Oreal
    Inventor: Philippe Touzan
  • Publication number: 20010051191
    Abstract: A composition and a method for treatment of urinary tract dysfunction and, particularly, non-bacterial cystitis and, even more particularly, non-bacterial chronic interstitial cystitis. The composition primarily relies upon the use of a bioflavonoid and, particularly, that bioflavonoid known as quercetin. The quercetin is mixed with a proteolytic digestive enzyme protease, such as bromelin and papain, as the primary active ingredients. However, the composition may optionally and beneficially include other cystitis affecting agents, such as cranberry, as well as some other active and non-active ingredients.
    Type: Application
    Filed: May 2, 2001
    Publication date: December 13, 2001
    Inventor: Floyd A. Katske
  • Publication number: 20010026813
    Abstract: Disclosed are a Scutellariae Radix extract and a pharmaceutical preparation comprising the extract as a pharmaceutically effective ingredient. With significant neuroprotective activity, but no toxicity, the Scutellariae Radix extract is suitable for use in the prophylaxis and treatment of brain diseases, such as apoplexy, Parkinson's disease and senile dementia.
    Type: Application
    Filed: February 6, 2001
    Publication date: October 4, 2001
    Inventors: Ho-Cheol Kim, Duk-Kyun Ahn, Sun-Yeou Kim, Kyungho Suk, Young-Ok Kim, Kang-Hyun Leem
  • Publication number: 20010025059
    Abstract: A composition and a method for treatment of prostate related dysfunction and, particularly, non-bacterial prostatitis and, even more particularly, non-bacterial chronic prostatitis. The composition primarily relies upon the use of a bioflavonoid and, particularly, that bioflavonoid known as quercetin. The quercetin is mixed with a proteolytic digestive enzyme protease, such as bromelin and papain, as the primary active ingredients. However, the composition may optionally and beneficially include other prostatitis affecting agents, such as zinc derived from zinc gluconate, cranberry, saw palmetto, as well as some other active and non-active ingredients.
    Type: Application
    Filed: January 9, 2001
    Publication date: September 27, 2001
    Inventor: Floyd A. Kastke