Abstract: Disclosed is a safe substance which can inhibit the activity of aromatase (an enzyme capable of converting androgen into estrogen) to thereby effectively treat and/or prevent a sex hormone-dependent disease such as breast cancer occurring in a female person after menopause, as well as a climacteric disorder in a male person and metabolic syndrome caused by the accumulation of a visceral fat. Specifically disclosed is a therapeutic and/or prophylactic agent for a sex hormone-dependent disease, which is characterized by comprising at least one herbal extract selected from the group consisting of “Kokeiten” (golden root), prunella spike, sweet hydrangea leaf, milk thistle, a jasmine tea, “Bokusoku” (a bark of Quercus acutissima or a closely related plant thereof), “Tencha” (sweet tea), “Karensou” (Eclipta prostrata), “Youbaihi” (a bark of Myrica rubra Sie b. et Zucc.), French maritime pine, betel palm, asparagus, “Rouro” (a root of Rhaponticum unifloru m DC.

Abstract: The invention provides a cosmetic composition for topical use having anti-radical properties and including at least one plant extract of natural origin in a cosmetically acceptable medium, the composition being characterized in that said at least one plant extract of natural origin is insoluble.

Abstract: Disclosed herein are an anti-obesity agent from natural products based on angiogenesis inhibitory actions, and an angiogenesis inhibitor or a composition for inhibiting obesity, containing at least one selected from the group consisting of Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract. Because the Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract of the present invention exhibit angiogenesis inhibitory effects and obesity inhibitory effects, they may be usefully used as an agent for prevention and treatment of angiogenesis-related diseases or obesity.

Abstract: Disclosed are therapeutic hydrogels for atopic dermatitis and a method for preparing the same. The hydrogels comprises a biocompatible polymer, a polyalcohol, and a medicinal plant extract. The hydrogels can carry medicinally effective ingredients for a sustained period of time and absorb wound exudates properly. The hydrogels have suitable gel strength and, when applied to a wound, can prevent bacterial infection of the wound. Moreover, the methods employing radiation allow the polymer chains to be crosslinked to each other, and also bring about a sterilization effect in the final hydrogel. There are no problems of toxic residues in the hydrogels. They are easy to attach to the skin and concomitantly provide a cool feeling. Supported by the laminate of hydrophilic non-woven fabric sheet and polyethylene film, the hydrogel retain water for a prolonged period of time and thus are useful in the treatment of contact dermatitis and atopic dermatitis.

Abstract: The invention describes a nutraceutical composition and method for preventing/treating cancer comprised of A) quinones (2,3-dimethoxy-5-methyl-1,4-benzoquinone, thymoquinone, tocopherolquinone) B) compounds capable of maximizing oxidative mitochondrial function preferably riboflavin, FAD, FMN, 6,7-Dimethyl-8-(1-D-ribityl)lumazine, ribitol, 5,6-dimethylbenzimidazole, tetrahydrobiopterin, vitamin B1, lipoic acid, biotin, vitamin B6, vitamin B12, folate, B3, C and pantothenate C) lactic acid dehydrogenase inhibitors; 2?,3,4?5,7-pentahydroxyflavone, epigallocatechin gallate, quercetin, citric acid, rosemary, black walnut, clove, nutmeg, licorice root, coriander, cinnamon, ginger root, myrrh gum and green tea D) alkalizing agents: aloe vera, chlorella, wheat grass, apple cider vinegar, burdock root, kudzu root, alfalfa, barley grass, spirulina, parsley leaf, calcium, magnesium, potassium or bicarbonate salts E) potent tumoricidal herbs; gromwell root, wild yam, beth root, teasel root, balm of gilead bud, frankince

Abstract: The present invention relates to silver-ionized plant extraction liquid and the use thereof. Particularly, there are provided herein a silver-ionized liquid extraction liquid prepared by ionizing silver in a plant extraction liquid used as an electrolyte and an antimicrobial composition comprising the same.

Abstract: A propellant-free foamable transparent composition, foamable by mixing with air or by hand rubbing, comprises a water-immiscible oil composition comprising at least one water-immiscible oil, which may be a mineral oil or vegetable oil, a siloxane resin foam stabiliser which is miscible in the water-immiscible oil composition to form a transparent liquid, and potentially a siloxane resin solubilising agent. The composition may be used for cosmetic applications.

Abstract: Gelification is an important topic in many types of consumer products today, such as foods, cosmetical or medical products but also in paints or adhesives. The present invention relates to the field of gels and gelling material and their applications. In particular, the present invention relates to a gel comprising a liquid medium and a gel matrix comprising sheared cell wall material from ripe and soft botanical fruits, its preparation, its possible uses, a product comprising such a gel and the corresponding gel building material and its application.

Abstract: An object made of at least two layers is disclosed, in which a first layer is a biologically degradable water-soluble support material containing an active agent and connected to at least one second layer, which is made up of a biologically degradable but water-insoluble material in the form of fibers. The active agents can be pharmaceutical agents, cosmetics, cleaning agents, agrochemicals and biocides. The object serves for the controlled release of at least one active agent based on the effect of water. The fiber structure of the second layer permits a control of the speed of water entry and/or exit.

Abstract: A specially formulated oil seed and nut based natural product composition useful in lowering total serum cholesterol and low density lipoprotein levels and increasing high density lipoprotein levels in humans. The composition is preferably formed by heating a variety of types of oil seeds and nuts at a predetermined temperature and for a predetermined period of time, categorizing the individual types of seeds and nuts into individual sets, grinding the seeds and nuts in each set into a meal, and combining the meals from each set to form a single composition.

Abstract: A perfume-containing PIT emulsion which is suited to contribute to an excellent and long-lasting scenting of textiles during the use of a dryer. The PIT emulsion is simple for the user to handle and allows the user to better control the user's individual scent experience during the handling of textiles. The PIT emulsions can also be used for aroma therapy purposes and for the scenting of rooms. In addition, a kit made of detergents and the perfume-containing PIT emulsion, which enables the user to obtain optimal laundry scenting results.

Abstract: A method of use for a topical herbal formulation alone or in combination with oral administration of niacin (preferably a flush preparation) to prevent and/or treat dyshidrosis (pompholyx) and related skin diseases. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders.

Abstract: The invention refers to an isolated extract of walnuts of high efficiency and stability over time useful for the manufacture of a medicament for the treatment of viral, fungal and bacterial diseases, which is characterized in that it is obtained from a process comprising: i) Collecting unripe walnut fruits as raw material; ii) Preparing the raw material for the extraction; iii) Freezing the raw material prepared in the previous step; iv) Drying; v) Extracting in a time lower than 10 minutes; vi) Filtration; and vii) Final packaging. The invention also refers to its use for manufacturing a medicament for the treatment of bacterial, fungal and viral diseases and to a composition comprising it.

Abstract: An improved anti-bacteria wipe for cleansing and drying toilet seats in public restrooms that is biodegradable and destroys germs and bacteria on contact. The wipe is comprised of four layers. The sealing first layer in conjunction with the third layer contains the moisture of the second layer. The pre-moistened second layer is infused with a quick drying anti-bacteria solution that kills germs and bacteria on contact. The third layer is an ultra thin biodegradable plastic to prevent seepage between the second and fourth layers. The fourth layer is a dry absorbent material used to remove any remaining moisture from the toilet seat. The wipe is sealed in an outer pouch to maximize shelf life. The biodegradable wipe can easily and safely be disposed of following use with reduced environmental impact.

Abstract: Technical Field: Tea Technical Problem: To provide a drinkable tea having a high therapeutic effect against atopic dermatitis. Means for Solving: It is characterized in that it contains extracts drawn from one, two or more medicinal herbs selected from the group consisting of Lightyellow Sophora Root, Isatis Leaf, and Terminalia Fruit. Atopic dermatitis can be cured by improving allergic constitution from the inside of body owing to antibacterial effect and antiviral effect of Lightyellow Sophora Root, Isatis Leaf and Terminalia Fruit, antiallergic effect of Lightyellow Sophora Root and Isatis Leaf, and intestinal mucosal protecting effect of Terminalia Fruit, or by a synergistic effect of them.

Abstract: A taste improving agent containing as an active ingredient a whey mineral satisfying all the criteria (a), (b), (c), (d), and (e) below: (a) an ash content in an solid portion of the whey mineral is 25 to 75% by mass; (b) a calcium content in a solid portion of the whey mineral is less than 2% by mass; (c) a calcium content in an ash portion of the whey mineral is less than 5% by mass; (d) a lactic acid content in a solid portion of the whey mineral is 1.0% by mass or more; and (e) a pH of an aqueous solution containing 0.1% by mass of a solid portion of the whey mineral is 6.0 to 7.5.

Abstract: A biologically active composition which has desirable properties, for example, anti-microbial and anti-cancer properties is disclosed. A process for preparing active ingredient(s) of the composition of the present invention, including, for example, extraction of the active ingredient(s) from a natural product is also disclosed. The biologically active composition may be extracted from a part of a variety of the walnut species J. regia L.

Abstract: A Fraxinus excelsior seed extract that can be administered for therapeutic treatment of a subject, including a human, by blocking fat synthesis, activating PPAR-alpha, increasing hypoglycemic activity, reducing bodyweight, controlling fasting plasma insulin levels against hyperinsulinemia, and promoting insulin sensitivity and causing a beneficial acute insulinotropic effect. The Fraxinus excelsior seed extract includes, inter alia, an isolated compound (2S,3E,4S) 2H-Pyran-4-acetic acid-3-ethylidene-2-[(6-O-?-D-glucopyranosyl-?-D-glucopyranosyl) oxy]-3,4-dihydro-5-(methoxycarbonyl)methyl ester, commonly called excelside A, an isolated compound (2S,3E,4S) 2H-Pyran-4-acetic acid-3-ethylidene-2-[(6-O-?-D-glucopyranosyl-?-D-glucopyranosyl)oxy]-3,4-dihydro-5-(methoxycarbonyl) 2-(4-hydroxyphenyl)ethyl ester, commonly called excelside B, and the compounds G15, G13, nuzhenide, and oleoside dimethyl ester.

Abstract: The present invention relates mainly to a cosmetic process for making up and/or caring for keratin material(s), comprising the application, on contact with a keratin material, of at least one cosmetic composition comprising at least 75% by weight, relative to its total weight, of compound(s) approved for food use and having a gloss value at least greater than or equal to about 5.

Abstract: The present invention relates to a composition comprising a Hypericum perforatum flower extract in combination with a synergetic agent and uses thereof for hair growth.

Abstract: A method for promoting restful, quality sleep in an individual comprising the administration of a composition comprising Lemon balm extract and one or more of Mesua ferrea plant powder, a source of reserpine, Catnip powder and Jamaica dogwood for the promotion of a feeling of relaxation conducive to the induction of sleep in an individual.

Abstract: The present invention relates to a silver-ionized plant extraction liquid and the use thereof. Particularly, there are provided herein a silver-ionized liquid extraction liquid prepared by ionizing silver in a plant extraction liquid used as an electrolyte and an antimicrobial composition comprising the same.

Abstract: Disclosed is a novel herbal composition comprising extract of Quercus infectoria having rich and effective concentration of as antioxidants and phenolic compounds. Further the present invention provides a process for preparing said composition and use thereof in cosmeceuticals, pharmaceuticals and health drinks for treating oxidative stress and other life style diseases.

Abstract: The invention relates to a pharmaceutical composition and the use of same for treating diseases that are caused by microorganisms, and as a cosmetic. In one embodiment, the pharmaceutical composition comprises an extract of liquorice root and oak bark in combination with dexpanthenol.

Abstract: The use of i) finely divided knotwood, or ii) an extract, obtained by extracting knotwood with a polar solvent and recovering the extract, as an antioxidative agent. A fraction of the extract may also be used as an antioxidative agent.

Abstract: A topical herbal formulation for preventing and/or treating dyshidrosis (pompholyx), non-responsive to topical steroids. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders. The active ingredients within the formula include a combination of dry, aqueous, acid and alcohol extracts of black walnut hull (Juglans Nigra), wormwood (Artemisia Absinthium), tumeric rhizome (Curcuma Longa), garlic (Allium sativum), chamomile (Matricaria Chamomile), licorice root (Glycyrrhiza Glabra), St Johns wort (Hypericum perforatum), aloe vera, niacin and herbal anti-bacterial agents.

Abstract: A device having a squeezable hollow member connected to a medication chamber in turn connected to a hollow tube fitted with an absorbent tip. The device may be used to conveniently administer a medication to an inflamed tissue. A method of providing a medication to an inflamed tissue is also provided.

Abstract: Disclosed are therapeutic hydrogels for atopic dermatitis and a method for preparing the same. The hydrogels comprises a biocompatible polymer, a polyalcohol, and a medicinal plant extract. The hydrogels can carry medicinally effective ingredients for a sustained period of time and absorb wound exudates properly. The hydrogels have suitable gel strength and, when applied to a wound, can prevent bacterial infection of the wound. Moreover, the methods employing radiation allow the polymer chains to be crosslinked to each other, and also bring about a sterilization effect in the final hydrogel. There are no problems of toxic residues in the hydrogels. They are easy to attach to the skin and concomitantly provide a cool feeling. Supported by the laminate of hydrophilic non-woven fabric sheet and polyethylene film, the hydrogel retain water for a prolonged period of time and thus are useful in the treatment of contact dermatitis and atopic dermatitis.

Abstract: A composition protects against, minimizes the effects of, and hastens recovery from the typical symptoms associated with an alcohol induced hangover. The composition includes superoxide dismutase (SOD), and prickly pear cactus (OFI). In addition, sesamin and alpha-lipoic acid work with the SOD and OFI for enhanced antioxidant and therapeutic effects. Other ingredients can be added to the composition for additional treatment of symptoms.

Abstract: A method of using a plant stem cell/plant growth hormone chelation preparation, including determining from medical testing the toxic condition of a patient, selecting a plant stem cell/plant growth hormone plant extract concentrate from buds of at least one plant having nutritional and medicinal constituents, such as from black poplar, grape vine, mountain pine, silver birch, white willow, European Elder. For oral administration of the plant stem cell/plant growth hormone plant extract is administered in an amount of about 3-15 drops, diluted in about half a glass of water, taken three times a day and continue for about 3 to 6 months or until a follow up testing provides a negative result. Depending on he state of toxicity, a combination of plant stem cell/plant growth hormone extracts may also be administered. A biologically active extract form at least two of the buds from the group of black poplar, grape vine, white willow, European elder and silver birch is also disclosed.

Abstract: Disclosed herein is a natural composite preservative comprising extracts from Camellia sinensis, Matricaria recutita, Citrus grandis, Magnolia biondii, propolis, Thujopsis dolabrata and Salix alba, in combination. The natural composite preservative has potent antibacterial activity against a wide spectrum of microorganisms in addition to being safe for the body, producing neither toxicity nor irritation, and thus can be applied to cosmetics, pharmaceuticals, and foods.

Abstract: Supplemental compositions, and methods for administering same to a user, are provided for promoting a restful night's sleep by speedily inducing a person to fall asleep and to maintain sleep, as well as alleviating minor aches and pains so as to further improve the quality of a person sleep. The supplemental composition may include at least an extract of Valerian Root, an extract of Willow Bark and Melatonin or a derivative thereof. The supplemental composition may be provided for consumption at least one time daily, e.g., prior to sleep.

Abstract: This invention relates to a method for the natural topical treatment of portions of skin of a person afflicted with a skin disorder such as dry skin, eczema, itchy skin, red skin, itchy eczema, inflamed skin, and/or cracked skin for the removal of itch and the restoration of the affected areas of skin to a normal condition. The natural treatment of a skin disorder initially involves formation of a natural ointment from the ingredients identified as lard; Marigold flowers; and pure beeswax. The natural ointment is formed by combination of the ingredients which includes heating. The ointment is then applied twice daily to affected areas of skin until a natural cure of the skin disorder is obtained. In addition, a therapeutic compress is applied to the affected skin. The compress may include Colts Foot Leaf, White Oak Bark, Burdock Root, Horsetail Herb, and water.

Abstract: This invention involves a traditional Chinese medical preparation, its preparation and use. The present Chinese medicine that treats periodontitis is a pharmaceutically acceptable oral preparation containing fleece-flower, dried rehmanria, licorice, fresh-water turtle shell, dogwood fruit, dodder seed, derla andrographis and Tokyo violet herb as active ingredients and supplementary material. By adopting supercritical CO2 fluid extraction technique for some materials, the containing of the effective ingredients of the preparation are ensured. With a novel and reasonable formula and definite curative effects, this invention provides periodontitis sufferers with a reliable medicine.

Abstract: The present invention relates to an extract having healing activity on injuries, which is obtained by extracting Astragali Radix, Ginseng Radix, Carthami Flos, Angelicae Gigantis Radix, Cnidii Rhizoma, Rehmanniae Radix Preparata, Paeoniae Radix and Cinnamomi Cortex Spissus with water while heating, and a pharmaceutical composition for treating injuries, a health food for post-surgical recovery and an animal feed containing said extract as the active ingredient.

Abstract: A composition and method is disclosed for suppressing infections and treating one or more injured or diseased aquatic vertebrate animals, by adding to the water containing the aquatic animal(s) a solution containing the extracted juice and fine particles of walnut husks or the combination of walnut husks and walnut leaves of the walnut trees of the genus Juglans, family Juglandaceae (also referred to herein as “Juglans blend”). Effective amounts of walnut husks or the combination of walnut husks and walnut leaves which inhibit or promote recovery from aquatic bacterial, fungal, protozoan, and dinoflagellate diseases on the surface of or in the skin of the animal or from wounds and abrasions, or to control or eliminate metazoan parasites, or to control or eliminate aquatic single-celled green algae are in the range from 0.035 grams to 0.

Abstract: The inventions relates to the use of silica in the formulation of antifungal composition for the treatment of cutaneous mycoses, and method to manufacture an antifungal powder with boric acid and silica.

Abstract: The present invention relates to natural compositions for lowering blood pressure, and treating various conditions associated with the occurrence of high blood pressure. These compositions can comprise two or more of the following ingredients in amounts which are effective to treat blood pressure conditions, e.g., (a) Hainan Holly leaf (e.g., Ilex hainanensis Merr.), (b) Chinese Hawthorn fruit (e.g., Crataegus pinnatifida Bge. or Crataegus cuneata Sieb. et Zucc.), (c) Garden radish seed (Raphanus sativus L.), and (d) Oriental persimmon leaf (Diospyros kaki L.f).

Abstract: An allergy preventive or itching preventive food containing persimmon leaves or a persimmon leaf extract, a persimmon leaf extract-containing cosmetic composition having the action of improving allergic rough skin conditions or alleviating itching, an allergy or itching preventive or therapeutic composition.

Abstract: A mouth rinse composition that is safe even if accidentally ingested, can be easily used by aged persons and children without uncomfortable feeling, and is clearly distinguished from the conventional mouth rinse compositions, comprises a combination of an extract of a persimmon or persimmon tannin and an extract of grapefruit seed, which effectively sterilize wide range of offending bacteria causing deterioration in intra-oral environment, such as dental caries, periodontal disease, oral odor and coated tongue, present in an oral, and an algefacient and/or an edulcorant gentle to teeth, which makes the composition easy to use for aged persons and children.

Abstract: This invention relates to a method for the natural topical treatment of portions of skin of a person afflicted with a skin disorder such as dry skin, eczema, itchy skin, red skin, itchy eczema, inflamed skin, and/or cracked skin for the removal of itch and the restoration of the affected areas of skin to a normal condition. The natural treatment of a skin disorder initially involves formation of a natural ointment from the ingredients identified as lard; Marigold flowers; and pure beeswax. The natural ointment is formed by combination of the ingredients which includes heating. The ointment is then applied twice daily to affected areas of skin until a natural cure of the skin disorder is obtained. In addition, a therapeutic compress is applied to the affected skin. The compress may include Colts Foot Leaf, White Oak Bark, Burdock Root, Horsetail Herb, and water.

Abstract: The compositions of this invention comprise a mixture of (1) phenylalanine and a dietary food supplement, (2) leucine and a dietary food supplement, and (3) hydrocinnamic acid and a dietary food supplement. The compositions are used for medicinal purposes to alleviate a variety of maladies.

Abstract: The invention concerns a formulation containing phosphatidylserine (PS) and/or lyso-phosphatidylserine for preventing and treating mental and physical stress states, where the phosphatidylserine is, among others, combined with plant extracts or essences. Daily doses of 50 to 1000 mg PS are envisaged within the scope of the present invention which are administered over a maximum period of six months. Preferred subjects are humans of 10 to 50 years of age.

Abstract: Provided are methods and compositions useful for treating disease and disorder associated with oxidative damage and the like. The methods and compositions are useful in the treatment of such disorders as Parkinson's disease. The compositions comprise an aqueous medium having dispersed or dissolved therein NAD (or a derivative thereof), glutathione (or a derivative thereof) and may further include an herbal therapeutic agent and/or an analgesic agent, wherein the composition is effective when delivered to the mucosal membrane.

Abstract: This application relates to dermatological agents for treating dermatological disorders. The dermatological agents include a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals, a moisturizing agent in an amount sufficient to facilitate hydration of the skin, and a pharmaceutically acceptable carrier. Preferred fruit extracts include extracts from apricots, apples, peaches, pears, pineapples, papayas, pomegranates, cherries, kiwis, tangerines, grapes, and oranges. The most preferred extract is extract from pomegranate.

Abstract: This invention discloses a topical herbal formulation for preventing and/or treating dyshidrosis (pompholyx), non-responsive to topical steroids. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders. The active ingredients within the formula include a combination of dry, aqueous, acid and alcohol extracts of black walnut hull (Juglans Nigra), wormwood (Artemisia Absinthium), tumeric rhizome (Curcuma Longa), garlic (Allium sativum), chamomile (Matricaria Chamomile), licorice root (Glycyrrhiza Glabra), St Johns wort (Hypericum perforatum), aloe vera, niacin and herbal anti-bacterial agents.

Abstract: The present invention relates to a treating method for hair growth inhibition, which comprises administering (A) the extract of a plant of the family Juniperus or a malt. In addition, the present invention relates to a dermatologic composition for external use, which comprises (B) an elastase inhibitor or neutral endopeptidase inhibitor, and the above-described component (A) and/or (C) at least one proteolytic enzyme selected from the group consisting of papain, trypsin, chymotrypsin, pepsin, bromelain, ficin and pancreatin.

Abstract: Skin cosmetics which are excellent in moistness and persistency of moisture-keeping effect, show light sense of touch when used and have excellent periodical stability. In addition, there are provided skin cosmetics which do not cause stickiness after their use, are excellent in rough skin improving and preventing effects, wrinkle preventing and improving effects, dinginess improving effect and the like, and also have an effect in providing the skin with smoothness and liveliness. Also, in the case of skin cleansing compositions, they exert such effects that they can provide the skin with liveliness and moistness after washing and can effectively remove fishy and ammonia smells or the like filthy smell adhered to the hand, the skin and the like. A skin cosmetic characterized in that it contains (A) at least one substance selected from seed extracts and seed hull extracts of a plant belonging to the genus Carya of the family Juglandaceae in an amount of from 0.

Abstract: The present invention provides therapeutic compositions comprising extracts of the plant species Echinacea purpurea and Sambucus nigra and the extract(s) of at least one further plant selected from the group consisting of Hypericum perforatum. Commiphora molmol and Centella asiatica. The compositions of the invention are of particular utility in the management of inflammatory mucosal diseases of both viral and non-viral origin.

Abstract: The sugar mannose has been used to maintain urinary tract health in the face of E. coli infections. An optimal dose is disclosed to be of one teaspoon (two grams) three times a day for one to two weeks or until symptoms subside. The maintenance dosage for prophalaxis is one-half teaspoon (1 gram) 1 to two times per day. Children's dosages are cut in half. For women who experience UTIs after sexual relations, one teaspoon is taken an hour prior to intimate relations and an additional one teaspoon immediately afterwards. It is further disclosed to use any of an extract of Crataeva nurvala, white willow bark, and pollen extract in conjunction with the mannose to provide further effect.