N-vinyl-2-pyrrolidone Patents (Class 424/78.24)
  • Patent number: 6491898
    Abstract: The invention relates to a tooth coating composition comprising (A) a polymer having one or more carboxyl or carbonyloxycarbonyl groups in its molecule, a weight average molecular weight of 10,000 to 5,000,000, a solubility of 1 g or higher in 100 g of absolute ethanol at 20° C. and a solubility of 10 g or lower in 100 g of water at 20° C., and (B) water or an alcohol having 1 to 5 carbon atoms. When coating teeth with the composition, the coating is not easily peeled by eating and drinking, but can be easily removed if necessary.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: December 10, 2002
    Assignee: Kao Corporation
    Inventors: Atsushi Yamagishi, Yukihiro Nakano
  • Patent number: 6464970
    Abstract: An improved method and composition for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric material prior to manipulation of the tissue during surgery. The composition comprises a solution of a polymeric material having a molecular weight of about 500,000 or above having a concentration of from about 0.01 to about 15%, by weight.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: October 15, 2002
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Eugene P. Goldberg, Yoseph Yaacobi
  • Patent number: 6440442
    Abstract: The present invention provides a mammalian teat dip composition capable of being used during a mammal's dry period comprising a solution of a film-forming polymer blend comprising a first polymer component which is an organic, solvent-soluble, preformed, thermoplastic polyurethane having no reactive isocyanate groups and a second polymer component which is a hydrophilic poly(N-vinyl lactam), said blend capable of withstanding exposure to water without significant loss of said hydrophilic poly(N-vinyl lactam) in an amount sufficient to form a water-resistant film upon topical application to mammalian skin; and wherein said blend comprises from about 10 to about 80 weight percent of said first polymer in combination with said solvent and from about 1 to about 20 weight percent of said second polymer; and at least one antimicrobial agent in an amount sufficient to treat and protect mammalian skin from infection; wherein said composition is capable of being removed by peeling.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: August 27, 2002
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian, Alfredo Vinci
  • Patent number: 6423332
    Abstract: The present invention provides a composition and method for augmenting soft tissue, which composition includes a continuous phase that is a solid at temperatures less than about 10° C. or greater than about 30° C. and is a fluid at temperatures between about 10° C. and about 30° C., and which contains an aqueous solvent having dissolved therein a hydrogel and a dehydrating agent, and a discontinuous phase containing a plurality of hydrophilic hydrogel particles that are swellable in the aqueous solvent, that are not biodegradable for periods of time in excess of one year, and that have a hydrated diameter of greater than about 25 microns upon hydration by physiologic fluid; wherein the final volume of the hydrophilic hydrogel particles upon hydration by physiologic fluid is substantially the same as the initial volume of the composition used to augment the soft tissue.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: July 23, 2002
    Assignee: Ethicon, Inc.
    Inventors: Shawn T. Huxel, Ram L. Kataria, Joel S. Rosenblatt
  • Patent number: 6395289
    Abstract: The invention discloses a mammalian teat dip for controlling mastitis, a method for preparing the composition and a method of treatment of mammals. The composition contains a film-forming polymer blend, at least one antimicrobial and a sodium bicarbonate buffering agent. The polymer blend contains a solvent-soluble, thermoplastic polyurethane and a hydrophilic poly(N-vinyl lactam). Upon application to mammalian skin, this composition leaves a long-lasting, water-resistant, residual, elastic film that treats and protects mammalian skin from infection.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: May 28, 2002
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian, Alfredo Vinci
  • Patent number: 6352689
    Abstract: A composition for use as a post-foaming shaving gel, for example, comprising about 3% to about 20% by weight of the composition of a surfactant system, about 0.05% to about 10% by weight of the composition of poly(ethylene oxide) and polyvinylpyrrolidone, in a combined amount, wherein the poly(ethylene oxide) and the polyvinylpyrrolidone are present in a weight ratio of about 1:10 to about 10:1, and about 0.1% to about 10% by weight of the composition of a post-foaming agent.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: March 5, 2002
    Assignee: S. C. Johnson & Son, Inc.
    Inventor: Thomas J. Szymczak
  • Patent number: 6300442
    Abstract: A process of making a cosmetically or pharmaceutically-acceptable emulsion or gel composition which comprises: (a) heating a reaction mixture comprising, by weight, about 5-70% of a vinyl monomer in about 30-95% of an oil as solvent, wherein said oil is selected from the group consisting of a silicone oil, a mineral oil and a water-insoluble organic ester and a free radical initiator, optionally in the presence of a crosslinking agent and/or an oil soluble surfactant, with agitation, under an inert gas, at about 40-150° C., wherein the oil is present in an amount sufficient to keep the resultant vinyl polymer in a stirrable state until the end of the polymerization, (b) adding a surfactant, if a suitable surfactant was not present during polymerization, and, (c) then adding water to form an oil-in-water, a water-in-oil or a water-in-oil-in-water emulsion or gel, in a volume ratio of oil-in-water of 30:70 to 10:90, or water-in-oil of 90:10 to 30:70.
    Type: Grant
    Filed: March 13, 1999
    Date of Patent: October 9, 2001
    Assignee: ISP Investments Inc.
    Inventors: Krystyna Plochocka, Jui-Chang Chuang, Jenn S. Shih
  • Patent number: 6294594
    Abstract: A denture adhesive base composition consisting essentially of polyvinyl pyrrolidone and ethylene oxide polymer. A denture adhesive composition including this base composition is also provided with other optional adhesive components. Also is provided a method for formulating a novel denture adhesive base composition consisting essentially of polyvinyl pyrrolidone and ethylene oxide polymer.
    Type: Grant
    Filed: September 12, 2000
    Date of Patent: September 25, 2001
    Assignee: Block Drug Company, Inc.
    Inventors: Michael J. Borja, Alan A. Halecky
  • Patent number: 6281251
    Abstract: Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: August 28, 2001
    Assignees: University of Kentucky Research Foundation, The Medical College of Hampton Roads, Eastern Virginia Medical School
    Inventors: George Digenis, Philip Fowler, Kazuya Matsumoto, Gustavo Doncel
  • Patent number: 6231848
    Abstract: The present invention relates to topical products intended for use as prophylactic or curative agents for bacterial skin infections, containing at least one polymeric complex substantially consisting of hydrogen peroxide, a suitable polymer for the complex formation thereof, possibly another bactericidal compound and possibly a metal salt or a metal colloid.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: May 15, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Jörg Breitenbach, Bernhard Fussnegger, Siegfried Lang
  • Patent number: 6203812
    Abstract: The invention discloses a mammalian teat dip for controlling mastitis, a method for preparing the composition and a method of treatment of mammals. The composition contains a film-forming polymer blend and at least one antimicrobial. The polymer blend contains a solvent-soluble, thermoplastic polyurethane and a hydrophilic poly(N-vinyl lactam). Upon application to mammalian skin, this composition leaves a long-lasting, water-resistant, residual, elastic film which treats and protects mammalian skin from infection.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: March 20, 2001
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian
  • Patent number: 6190651
    Abstract: A solution for preserving contact lenses for shipping, which comprises a polyvinyl pyrrolidone having a weight average molecular weight of from 500 to 200,000, and which contains no surfactant.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: February 20, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Kazuhiko Nakada, Yutaka Matano
  • Patent number: 6180127
    Abstract: This invention discloses slow release formulations for use in application of volatile insect repellents. A copolymer of polyvinyl pyrrolidone and an alkyl group of 4-30 carbons provides the slow release properties. The formulations are characterized by high residual action, low skin penetration, and high resistance to removal by water.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: January 30, 2001
    Assignee: AquaSource, Inc.
    Inventors: Gary J. Calton, Sidney R. Siemer, Louis L. Wood