Abstract: It is an object of the present invention to attach a biopolymer composition to a synthetic polymer substrate without the use of a toxic adhesive. The present invention provides a medical composition, wherein a synthetic polymer substrate and a composition mainly composed of a biopolymer directly adhere to each other due to dissolution of the surfaces thereof.
Abstract: This disclosure provides a medical device and a method of forming the medical device. The medical device comprises a coating comprising a type-one polymer and a type-two polymer. The type-one polymer comprises at least two different blocks, at least one L1 block with the formula ; and at least one L2 block with the formula Medical devices comprising these polymers, mixtures of these polymers with therapeutic agents, and methods of making these polymers and mixtures are within the scope of this disclosure.
Abstract: The present invention relates to a novel dosage form, to a process for preparing the dosage form and to the use of the dosage form in the treatment of neurological and psychiatric disorders.
Type:
Application
Filed:
February 28, 2008
Publication date:
January 27, 2011
Inventors:
Allan James Clarke, Ian Paul Conn, Simon Richard Hicks, Yu Li, Xiaolei Wang
Abstract: Embodiments of the invention generally provide pharmaceutical drug compositions, methods of preparing oral drug compositions, such as extended release dosage compositions, and methods for treating antidepressant or smoking cessation. In one aspect, the invention provides a pharmaceutical formulation comprising a core, including bupropion and its salt derivatives, and a coating. The coating may include from about 5% to about 99% by weight of the coating of a pharmaceutically acceptable pH-independent polymer. The coating may further include from about 0.001% to about 30% by weight of the coating of a surfactant. In another aspect, the invention provides methods for preparing and administering a pharmaceutical composition in oral dosage form, such as a tablet.
Type:
Application
Filed:
October 8, 2010
Publication date:
January 27, 2011
Inventors:
San-Laung Chow, David Wong, Damian Garcia
Abstract: The present invention relates to particle compositions comprising a core particle that is partially coated with a first hydrophilic deposit and a hydrophobic polymeric finish, contains a small amount of water, and a compatible active present in the deposit, the finish or both. Additional alternating deposits, hydrophobic, hydrophilic or both, can be present between the first hydrophilic deposit and the hydrophobic polymeric finish. Similarly, additional compatible actives can be present in one or more of the additional alternating deposits. The invention also relates to methods of preparing the particle compositions.
Type:
Application
Filed:
September 2, 2010
Publication date:
January 20, 2011
Inventors:
FRANCIS MARTIN FRIEL, WILSON AN-TUEN LEE, AYA SHIDARA, CLARA G. MERCADO, ERIC JOHN LEAVER
Abstract: The present invention provides a method and apparatus for positioning the core of the compression coated tablet in manufacturing techniques for the production of such tablets.
Abstract: The present invention is a solid effervescent mixture for oral absorption which comes in the following forms: tablets, pills, granules, chewing gum, and candy. The formulation and preparation methods of the solid effervescent mixture are also disclosed. The solid effervescent formulation is administrated orally without water for dissolving and swallowing. In general, the present invention is directed to a solid or other mixture that comprises an orally administrable therapeutic agent or agents, in combination with an effervescent formulation that may be used as an absorption enhancer for the therapeutic agents across the buccal, sublingual, and/or gingival mucosa in order to relieve local and systemic symptoms rapidly.
Abstract: Drug delivery balloons have densely packed crystals of small particle size of the drug thereon. An amorphous drug coating is applied to a balloon surface and annealed to provide the crystals. The balloon surface is nucleated to induce formation of drug crystals in the annealing step to provide the crystals in high density with small size.
Type:
Application
Filed:
June 14, 2010
Publication date:
January 20, 2011
Applicant:
BOSTON SCIENTIFIC SCIMED, INC.
Inventors:
Steve Kangas, Michael Sean Owens, Jon Patterson, Dave Ekberg, Erik Haun, Eric Henderson, Aaron Foss, Yen-Lane Chen
Abstract: Embodiments of the invention include multi-layered coatings for controlling the elution rates of active agents and methods. In an embodiment, the invention includes a method of applying an elution control coating to a substrate. The method can include depositing a coating solution onto the substrate to form a base layer. The method can also include selecting a desired concentration of the solvent based on a desired elution rate. The method can further include removing solvent from the base layer to reach a desired concentration of the solvent and depositing a layer of parylene on the base layer. In an embodiment, the invention can include a medical device including a substrate, a base layer, and a porous layer. The base layer can include a polymeric matrix and an active agent dispersed within the polymeric matrix. The porous layer can include parylene. Other embodiments are also included herein.
Abstract: The invention provides a method for preparing microparticles comprising mixing a first cross-linkable reagent in aerosol form with a second cross-linking reagent in aerosol form to thereby to form microparticles.
Abstract: The present invention relates to pharmaceutical compositions comprising granules containing at least one recombinantly produced purified microbial lipase, the use of said pharmaceutical compositions for the manufacture of a medicament for the prevention or treatment of certain diseases or disorders like pancreatic endocrine insufficiency, and a process for the manufacture of said pharmaceutical compositions.
Type:
Application
Filed:
January 2, 2009
Publication date:
January 13, 2011
Applicant:
ABBOTT PRODUCTS GMBH
Inventors:
Florian Unger, George Shlieout, Andreas Koerner
Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.
Abstract: The present invention is directed to pharmaceutical compositions comprising a plurality of taste-masked non-opioid analgesic/opioid analgesic drug-containing microparticles, dosage forms comprising such pharmaceutical compositions (such as an orally disintegrating tablet), and methods of making the pharmaceutical compositions and dosage forms of the present invention. Dosage forms comprising the pharmaceutical compositions of the present invention are improved homogeneous blends of non-opioid and opioid analgesics which provide for more convenient and palatable administration of drug combinations, for example for treating pain.
Type:
Application
Filed:
May 3, 2010
Publication date:
January 6, 2011
Inventors:
Gopi Venkatesh, Michael Gosselin, James Clevenger, Jin-Wang Lai
Abstract: The present invention provides a method and apparatus for dry coating solid dosage forms. The method includes the steps of placing solid dosage forms in a rotatable, electrically grounded housing, and spraying a film forming polymer powder composition into the housing during rotation thereof to form a polymer coating on the solid dosage forms, the polymer powder composition being sprayed using an electrostatic spray gun, and curing the coated solid dosage forms.
Abstract: The present invention is directed to pharmaceutical compositions comprising a plurality of taste-masked high-dose/low-dose drug-containing microparticles, dosage forms comprising such pharmaceutical compositions (such as an orally disintegrating tablet), and methods of making the pharmaceutical compositions and dosage forms of the present invention. Dosage forms comprising the pharmaceutical compositions of the present invention are improved homogeneous blends of high-dose and low-dose drugs which provide for more convenient and palatable administration of drug combinations, for example for treating pain, hyperglycemia, cardiovascular disease, and allergies.
Type:
Application
Filed:
May 3, 2010
Publication date:
December 30, 2010
Inventors:
Gopi Venkatesh, Michael Gosselin, James Clevenger, Jin-Wang Lai
Abstract: A process for producing a compressed solid dosage form containing an active ingredient. The process includes a step of preparing core elements containing the active ingredient. Optionally the core elements are coated with a pharmaceutically acceptable coating layer to form coated pellets. The core elements or pellets are treated with an anti-static agent and compressed with suitable excipients to form the compressed solid dosage form. Preferred anti static agents are starch, microcrystalline cellulose, kaolin, bentonite, silicates, silicon dioxide, cellulose, stearic acid, sodium stearyl fumarate and glyceryl behenate.
Abstract: A method of imparting sustained antimicrobial properties throughout a material or substrate using an antimicrobial polymerizable silicon-containing quaternary ammonium salt monomer in a solvent to form a quaternary ammonium salt solution; and mixing the silicon-containing quaternary ammonium salt solution with at least a second monomer or a polymer or coating a solid polymer. Depending on the nature of the second monomer or polymer and the reaction conditions; a copolymer with the first monomer or a homopolymer will form, such that a polymeric material, substrate or formed plastic product comprising the copolymer or homopolymer or blended with the coated concentrate will have sustained antimicrobial properties. This method can be used to make formed plastic products, thin layer films and other products having sustained antimicrobial properties.
Type:
Grant
Filed:
March 22, 2006
Date of Patent:
December 28, 2010
Assignee:
Biosafe Inc.
Inventors:
Gerry D. Getman, Matt Bootman, Donald Wagner, Jr., Thomas Ward
Abstract: A laminin-modified polymeric hollow conduit is provided for promoting nerve regeneration across the gap between severed ends of a nerve. The conduit is manufactured by a method involving gas plasma treatment. Utilizing the laminin-modified conduit, functional recovery has been achieved in mammals with a severed spinal cord.
Type:
Grant
Filed:
October 17, 2006
Date of Patent:
December 28, 2010
Inventors:
Henrich Cheng, Yi-Cheng Huang, Pei-The Chang, Yi-You Huang
Abstract: The present invention herein provides an imidafenacin-containing orally rapidly disintegrating tablet which is excellent in the photostability. The present invention comprises the steps of: (A) granulating imidafenacin together with starch to thus give a granulated product having an imidafenacin concentration ranging from 0.001 to 3% by mass and a starch concentration ranging from 40 to 99.999% by mass; (B) covering the granulated product prepared in the step (A) with a non-cellulosic coating agent; and (C) blending the granulated product obtained in the preceding step (B) with an excipient and a disintegrating agent and then forming the resulting mixture into a tablet according to the compression molding technique.
Abstract: A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described.
Type:
Application
Filed:
July 14, 2010
Publication date:
December 16, 2010
Inventors:
Unchalee Kositprapa, Avinash Nangia, John Cardinal, Robert I. Goldfarb
Abstract: This invention provides novel solid pharmaceutical compositions and processes for the bulk production of said compositions. This invention also provides methods of using the pharmaceutical compositions in the treatment of cancer.
Abstract: A pharmaceutical composition for the oral administration of omega polyenoic fatty acids combined with one or more active principles incompatible therewith, is described; also described is a process for preparing said pharmaceutical composition.
Abstract: A device for vaporizing a composition. The device comprises a thermally conductive substrate having a surface, the surface comprising a thermally conductive surface structure. A dry composition capable of a solid to liquid phase change upon being heated to at least a select temperature is disposed on the surface structure. The surface structure is configured to form liquid droplets of the composition upon heating of the surface structure to at least the select temperature. The liquid droplets have a median diameter less than a median diameter of liquid droplets formed on a planar substrate surface heated to at least the select temperature.
Type:
Application
Filed:
May 27, 2010
Publication date:
December 2, 2010
Applicant:
Alexza Pharmaceuticals, Inc.
Inventors:
C.V. Krishnamohan Sharma, Mingzu Lei, Peter D. Noymer, Daniel J. Myers
Abstract: A method of producing silica-coated metal nanoparticles with at least one tetraalkoxysilane, from nanoparticles, referred to as metal nanoparticles, includes a quantity of at least one metal of zero oxidation state, a quantity of a catalytic hydrolysis composition, a quantity of liquid solvent medium and a quantity of water, so as to obtain a hydrolysis/condensation enabling the metal nanoparticles to be coated with silica, wherein the liquid solvent medium consists of at least one solvent chosen from the group formed by non-alcoholic organic solvents.
Type:
Application
Filed:
November 18, 2008
Publication date:
December 2, 2010
Applicants:
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE (I.N.S.A.T.), UNIVERSITE PAUL SABATIER (U.P.S.), CENTRE NATIONAL DELA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Fabien Delpech, Celine Nayral, Nancy El hawi
Abstract: The present invention provides compositions and methods of making and encapsulating one or more active agents in a chemical vapor deposition layer to enhance the stability.
Type:
Application
Filed:
May 21, 2010
Publication date:
November 25, 2010
Applicants:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, AEONCLAD COATINGS, LLC
Inventors:
Richard B. Timmons, Ceren Susut, Donald E. Owens, III, J. Brian Windsor, Rachel Kennedy Khorzad
Abstract: The present invention provides a system for delivery of an enteric coated active agent generally resistant to disintegration in an neutral environment having one or more active agents encapsulated by a polymer coating formed by chemical vapor deposition of one or more monomers on the one or more active agents to form a chemical vapor deposition polymer coating that controls the release of the one or more active agents in the gastrointestinal tract.
Type:
Application
Filed:
May 21, 2010
Publication date:
November 25, 2010
Applicants:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, AEONCLAD COATINGS, LLC
Inventors:
Richard B. Timmons, Ceren Susut, Donald E. Owens, III, J. Brian Windsor, Rachel Kennedy Khorzad
Abstract: The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a fine particle size detackifier. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either polyvinyl alcohol or a copolymer of polyvinyl alcohol. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.
Type:
Application
Filed:
April 28, 2010
Publication date:
November 18, 2010
Applicant:
BPSI HOLDINGS, LLC.
Inventors:
Thomas P. FARRELL, Jason TECKOE, Barry FRIEND, Scott GULIAN
Abstract: The present invention relates to liposomes comprising particles with cores of tungsten or tungsten in mixture with other metallic elements as the contrast enhancing material and to the use of such pharmaceuticals, specifically as contrast agents in diagnostic imaging and in particular in X-ray imaging of liver tumours.
Abstract: A coating composition is provided that is suitable for use on a medicament-contact surface. The coating composition preferably includes one or more acrylic-containing polymer and a carrier. In preferred embodiments, the coating composition is an aqueous dispersion or solution.
Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Type of surface properties that are altered by the disclosed methods include by electrostatic properties, hydrophobic properties and hydrogen bonding properties.
Abstract: Ocular implant devices (10, 20, 121) for the delivery of a therapeutic agent to an eye (101, 301) in a controlled and sustained manner. Dual mode and single mode drug delivery devices (10, 20, 121) are illustrated and described. Implants (10, 20) suitable for subconjunctival placement are described. Implants (121, 10, 20) suitable for intravitreal placement also are described. The invention also includes fabrication and implementation techniques associated with the unique ocular implant devices (10, 20, 121) that are presented herein.
Type:
Application
Filed:
December 28, 2009
Publication date:
October 28, 2010
Applicants:
Department of Health
Inventors:
Michael R. Robinson, Karl G. Csaky, Robert B. Nussenblatt, Janine A. Smith, Peng Yuan, Cynthia Sung, Matthew P. Fronheiser, Hyuncheol Kim
Abstract: This invention provides a compound of formula (I): or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; processes for the synthesis or manufacture of the compound of formula (I), or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; and the use of said compound, or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof, for the treatment of patients suffering from or subject to diseases, disorders or conditions involving cell survival, proliferation, and migration, including cardiovascular disease (e.g., arteriosclerosis and vascular reobstruction), cancer, (e.g., AML and malignant glioma)glomerulosclerosis, fibrotic disease and inflammation.
Type:
Application
Filed:
November 20, 2009
Publication date:
October 28, 2010
Applicant:
Millennium Pharmaceticals, Inc.
Inventors:
Ian Armitage, Michael E. Bourland, Craig J.S. Boyle, Martin Ian Cooper, Abu J. Ferdous, Marianne Langston
Abstract: The object of the present invention is to provide particles of a polymeric material containing cells therein, wherein said particles have a strength that is substantially greater than the microcapsules known in the state of the art.
Type:
Application
Filed:
June 25, 2008
Publication date:
October 28, 2010
Applicant:
UNIVERSIDAD DEL PAIS VASCO
Inventors:
Gorka Orive Arroyo, José Luis Pedraz Muñoz, Rosa María Hernández
Abstract: A personal skin cleansing wipe comprising a flexible substantially dry matrix formed from synthetic, woven, non-woven or knitted fibers impregnated with a substantially anhydrous antimicrobial, antiseptic, antifungal solution in an amount wherein the matrix retains its substantially dry characteristics and the treatment solution includes an amount of PVP-iodine as active in solution in glycol and or glycerin. The treatment solution, in addition to an effective amount of PVP-iodine as active, contains surfactants, preferably Tego® Betaine CK D, and optionally a compatible fragrance and/or moisturizer. The wipe is activated with water just prior to use.
Abstract: The invention relates to particles containing an active agent in the form of a co-precipitate to a method for producing said particles and to pharmaceutical forms containing said particles.
Abstract: The invention relates to single-layer oral disintegrating films having at least two distinct zones, which comprise nicotine and allow for effective buccal (=oral mucosal) absorption thereof.
Type:
Application
Filed:
December 9, 2008
Publication date:
October 21, 2010
Applicant:
Novartis AG
Inventors:
Stephan Meyer, Greg Slominski, Christopher Edward Fankhauser, Nicole Ouis
Abstract: The present invention provides a tablet coating composition including a cellulose polymer, a plasticiser, a sweetener, and a powdered flavour composition. The powdered flavour composition includes a flavourant associated with a solid carrier. The present invention also provides a pharmaceutical tablet including a core containing an active agent and a coating formed from the tablet coating composition.
Abstract: It has been desired to provide a method for producing a granulated preparation capable of maintaining a stability of a chemically unstable substance in a neutral or acidic region for a long period of time with a simple and safe method in a preparation procedure, and a tablet produced by using the method. The invention provides a granulation method in which an unstable substance is successively subjected to aqueous stabilization treatment and granulation procedure. Further, it became possible to provide a tablet which is absorbed in the intestine without losing the potency in a gastric region by forming an intermediate layer on a surface of the thus obtained granule and subsequently subjecting the granule to enteric coating.
Abstract: The present disclosure describes compositions operable for releasing nitric oxide under photochemical conditions. The compositions include a titanium dioxide nanomaterial and a nitric oxide-releasing compound deposited on the titanium dioxide nanomaterial that is operable to release nitric oxide under photochemical conditions. Titanium dioxide nanomaterials include, for example, titanium dioxide nanotubes. To facilitate the photochemical release of nitric oxide, some embodiments of the compositions further include a semiconductor that is deposited on the titanium dioxide nanotubes. Both the semiconductor and the nitric oxide-releasing compound may be deposited on the interior surface, exterior surface, or both of the titanium dioxide nanotubes. A polymer may wrap the titanium dioxide nanotubes to protect the nitric oxide-releasing compounds from moisture. Also disclosed herein are methods for producing such compositions and medical devices obtained therefrom.
Type:
Application
Filed:
March 30, 2010
Publication date:
September 30, 2010
Applicant:
Board of Regents, The University of Texas System
Inventors:
Kenneth J. Balkus, JR., Chalita Ratanatawanate
Abstract: The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets solvent such that the effective ingredient is exposed to a vapor-liquid interface of less than 50, 100, 150, 200, 250, 200, 400 or 500 cm?1 area/volume to, e.g., increase protein stability; and contacting the droplet with a freezing surface that has a temperature differential of at least 30° C. between the droplet and the surface, wherein the surface freezes the droplet into a thin film with a thickness of less than 500 micrometers and a surface area to volume between 25 to 500 cm?1.
Type:
Application
Filed:
June 20, 2008
Publication date:
September 30, 2010
Applicant:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Abstract: A spherical particle of the present invention contains a sugar alcohol and a crystalline cellulose and/or powdered cellulose, wherein the mass ratio between the sugar alcohol and the crystalline cellulose and/or powdered cellulose is within a range from 50:50 to 90:10, the particle size is within a range from 75 to 250 ?m, the sphericity is not less than 0.8, and the bulk density is not less than 0.6 g/ml. Further, a method for producing the spherical particle of the present invention includes a granulation step of rolling a sugar alcohol having an average particle size of not more than 40 ?m and a crystalline cellulose and/or powdered cellulose having an average particle size of not more than 50 ?m while spraying a liquid thereon.
Abstract: Co-therapy of an anti-obesity agent, a statin, is disclosed along with fixed combinations thereof. Atorvastatin and orlistat are preferred as the various components.
Abstract: The present invention relates to a quickly decomposing oral drug preparation, for the application of active ingredient combinations for smoking withdrawal, which contains nicotine, a nicotine salt, a nicotine derivative, or a substance that reacts to nicotine, in combination with another active ingredient, and the use of such a drug preparation for the treatment of smoking withdrawal, and the use of nicotine, and/or nicotine salts or derivatives, for the production of medications for the treatment of smoking withdrawal. The active ingredient that is to be administered, in combination, for this purpose is a centrally active ingredient, preferably an antidepressant for the fighting of psychic dependency in terms of a smoking withdrawal therapy. The administration of the active ingredient combination to the patient should be handled in a simple and reliable way and should exclude side effects to a large extent.
Type:
Application
Filed:
June 4, 2007
Publication date:
September 16, 2010
Applicant:
LTS Lohmann Therapie-Systeme AG
Inventors:
Hans-Rainer Hoffmann, Reto Brändli, Frank Theobald
Abstract: The invention relates to a vapor-deposition material for the production of optical layers of medium refractive index which comprises aluminum oxide and gadolinium oxide, dysprosium oxide and/or ytterbium oxide, to a process for the preparation thereof, and to the use thereof.
Type:
Grant
Filed:
January 28, 2004
Date of Patent:
September 7, 2010
Assignee:
Merck Patent GMBH
Inventors:
Martin Friz, Reiner Dombrowski, Uwe Anthes
Abstract: Water soluble, gelatin-free dip coatings for pharmaceutical solid dosage forms such as tablets comprising HPMC and xanthan gum, carrageenan, and mixtures thereof, or HPMC and castor oil or maltodextrin.
Type:
Grant
Filed:
June 27, 2007
Date of Patent:
August 31, 2010
Assignee:
McNeil-PPC, Inc.
Inventors:
Cynthia Gulian, Walter G. Gowan, Jr., Kishor B. Parekh, Joseph M. Morris, Thomas J. Markley, Dennis C. Wieand, Gerard P. McNally, Christopher Szymczak
Abstract: Disclosed herein are a protein chip substrate and a method for manufacturing the protein chip substrate. The method includes deposition of plasma polymerized ethylenediamine (PPEDA) having an amine group on plasma polymerized cyclohexnane (PPCHex) by inductively coupled plasma-chemical vapor deposition (ICP-CVD), thereby preventing non-specific adsorption of proteins on a slide surface.
Type:
Grant
Filed:
December 27, 2006
Date of Patent:
August 31, 2010
Assignee:
Sungkyunkwan University Foundation for Corporate Collaboration
Abstract: An implantable or insertable medical device is provided which contains the following: (a) a substrate, (b) a therapeutic agent-containable region disposed over the substrate, (c) a nanoporous polymeric layer disposed over the therapeutic agent-containable region and (d) a macroporous non-polymeric layer disposed over the nanoporous polymeric layer. The nanoporous polymeric layer largely regulates transport of species between the therapeutic agent-containable region and the exterior of the device. The macroporous non-polymeric layer has a larger pore size than the nanoporous polymeric layer and largely serves to isolate the polymeric material from surrounding tissue during in-situ delivery of the therapeutic agents.
Abstract: In the process of coating pharmaceutical tablets in a moving bed, the temperature of the tablets is measured by incorporating a temperature transducer in the form of tablet into the bed of tablets, and transmitting temperature data to an external receiver by wireless telemetry.