Abstract: A soft capsule film composition, comprising: (A) a native gellan gum; (B) one or more hydrophilic polysaccharides; (C) a starch or modified starch; (D) a plasticizer; and (E) water, wherein a gelling agent other than the native gellan gum and the one or more hydrophilic polysaccharides is not an essential component. The soft capsule film composition shortens drying time at room temperature, suppresses the stickiness of the surface of a film sheet, imparts film sheet strength which can withstand continuous production in factory manufacturing with a rotary die filling machine or the like, and enables the manufacture of a good soft capsule with high adhesiveness. For this reason, the soft capsule produced using the soft capsule film composition can be utilized for various uses such as drugs, quasi drugs, cosmetics, and foods.

Abstract: The present invention provides materials and methods for treating symptoms of neurological conditions. More specifically, the subject invention provides compositions and methods of their use for treating one or more symptoms and/or comorbidities of a neurological condition such as an infection, a neurodevelopmental disease, and/or a neurodegenerative disease. In preferred embodiments, the composition is administered to the subject via nasal administration.

Abstract: Lipid-based vesicles, typically herein called transfection competent vesicles (TCVs), configured to safely and efficiently deliver DNA, RNA, other nucleic acid and protein cargoes into target cells. The safety and efficiency are each, and both, achieved in part by eliminating organic solvents such as ethanol and detergents such as sodium dodecyl sulfate from the TCV loading processes (i.e., inserting a cargo into the TCV), TCV storage processes, and/or TCV delivery processes. The cargoes can also comprise nucleic acids complexed with a protein, such as a ribonucleoprotein (RNP). The systems, compositions, devices and methods, etc., herein, in some embodiments, can provide empty TCVs that can if desired be loaded at the bench without use of specialized equipment.

Abstract: The present invention relates to a method of manufacturing non-sintered liquid metal ink, and more particularly, to a method of manufacturing liquid metal ink manufactured without a sintering process. The method of manufacturing liquid metal ink according to an embodiment of the present invention includes: (a) inputting a solvent into liquid metal in a container at room temperature; (b) performing oxide film-removing treatment on the liquid metal of step (a); and (c) dispersing the liquid metal that has undergone step (b) in a form of nanoparticles through ultrasonic treatment.

Abstract: Lipid-based vesicles, typically herein called transfection competent vesicles (TCVs), configured to safely and efficiently deliver DNA, RNA, other nucleic acid and protein cargoes into target cells. The safety and efficiency are each, and both, achieved in part by eliminating organic solvents such as ethanol and detergents such as sodium dodecyl sulfate from the TCV loading processes (i.e., inserting a cargo into the TCV), TCV storage processes, and/or TCV delivery processes. The cargoes can also comprise nucleic acids complexed with a protein, such as a ribonucleoprotein (RNP). The systems, compositions, devices and methods, etc., herein, in some embodiments, can provide empty TCVs that can if desired be loaded at the bench without use of specialized equipment.

Abstract: RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation.

Abstract: A skin care, wound care, or oral care device, comprising an essential oil stabilized into a polymerizable substance.

Abstract: A winding head arrangement for an electric rotating machine includes a base body including an electrically conductive material having an electrically insulating coating, and a plurality of conductors made from a first metal material and connected to the base body via the electrically insulating coating by a first additive production method.

Abstract: A composition comprising microcapsules functionalized with polymerizable functional groups on the surface of said microcapsules wherein the functional groups form covalent bonds with monomers in the continuous phase to enhance the mechanical properties of the composition.

Abstract: A network of microfibers are fabricated with a core-shell construction from sustainable materials, where the core includes a phase-change material, such as coconut oil, and the shell includes a biomass, such as cellulose. The microfibers are made via a wet-wet electrospinning process utilizing a coaxial spinneret with an inner conduit and an outer conduit. The biomass and the phase-change material are coaxially extruded into a coagulation bath including a mixture of ethanol and water. The collected microfibers exhibit a beaded structure of PCM aggregates and biomass connecting regions between the aggregates and are effective to aid in the thermoregulation of the immediate environment surrounding the network. The microfibers are suitable for use in a variety of sustainable products such as wearable thermoregulating textiles, wall/ceiling panels, insulation, packaging material, and more.

Abstract: An ultra low density film and an ultra low density solid material are produced by the steps of providing a vessel, introducing two immiscible fluids into the vessel, adding nanocrystals to at least one of the two immiscible fluids, applying a shear force to the two immiscible fluids and the nanocrystals in a manner that causes the nanocrystals to self-assemble and form colloidosomes. The colloidosomes amass and evaporation of the two fluids produces dried colloidosomes. The ultra low density self-assembled colloidosomes are hollow self-assembled colloidosomes, which are formed into the ultra-low density film and the ultra-low density solid.

Abstract: A composition comprising, in a physiologically acceptable medium, a crosslinked hyaluronic acid (HA), having a degree of modification less than 1.9 mole %; a HA with a molecular weight of about 50 kDa or less; and/or an agent stimulating endogenous HA synthesis. Also disclosed is a cosmetic use of such composition in skin care and/or anti-ageing treatment.

Abstract: Phase change material compositions and methods for using the compositions to prepare substrate coatings or bulk blended polymers that advantageously lower friction between interacting substrate surfaces and lower substrate surface wear.

Abstract: This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced.

Abstract: Described herein is a cast-molding process for producing contact lenses in a relatively-short curing time from a lens-forming composition, which comprises (a) at least one thiol-containing compound or component, (b) at least one metal scavenger, and (c) at least one free radical scavenger and which has a pH of from about 2.5 to about 5. The addition of a chain-transfer agent into a lens-forming composition can reduce not only the curing time of the lens-forming composition but also reduce the elastic modulus of resultant crosslinked materials (e.g., contact lenses) from the lens-forming composition. The lower pH and the addition of metal scavenger and the free radical scavenger into the lens-forming composition can ensure that the lens-forming composition to have a shelf life of at least three days.

Abstract: A method for treating an oil-containing medium including oil or grease or both oil and grease includes the steps of combining algae with an oil-containing medium and allowing the algae to engulf or uptake at least a portion of the oil or grease in the oil-containing medium. A mixture for treating oil or grease or both oil and grease includes an oil-containing medium including oil or grease or both oil and grease and phagotrophic algae that engulf or uptake at least a portion of the oil or grease in the oil-containing medium.

Abstract: A topical mosquito control product includes active and inert ingredients. The active ingredients include natural materials and may include soybean oil, geraniol, cinnamon oil and cedar wood oil. The inert ingredients include natural materials and may include bee's wax, isopropyl alcohol, sunflower oil, salt, triethyl citrate and water.

Abstract: Methods of inducing or controlling particle motion in suspensions and colloids are described. In one aspect, a method of inducing particle motion in a suspension comprises contacting the suspension with a gas phase to establish at least one interface between the gas phase and continuous phase of the suspension. One or more gases of the gas phase are transferred across the interface to provide a solute gradient in the continuous phase, the solute gradient inducing motion of the suspended particles.

Abstract: Described herein is a cast-molding process for producing contact lenses in a relatively short curing time. The short curing time has been achieved by adding a chain transfer agent into a lens-forming composition.

Abstract: The present invention provides a capsule that is capable of suppressing volatilization of a highly volatile capsule content through the capsule shell and that is breakable. A breakable seamless capsule for a smoking equipment, comprising a content containing an oily ingredient and a capsule shell for encapsulating said content, wherein: the capsule shell contains a polysaccharide; the thickness of the capsule shell is 60 ?m or more; the volatilization content (VC) of the content after leaving the content to stand under an environment at a temperature of 25° C. and a relative humidity of 40% for 4 hours is 3.0 wt % or more with respect to the total weight of the encapsulated content; and the crush strength per diameter of the capsule is 3-8 N/mm.

Abstract: A composition comprising microcapsules functionalized with polymerizable functional groups on the surface of said microcapsules wherein the functional groups form covalent bonds with monomers in the continuous phase to enhance the mechanical properties of the composition.

Abstract: The invention relates to a method and system for generating droplets of an aqueous solution on a microfluidic chip with an air continuous phase. Specifically, the droplet generator according to the present invention is integrated into a microfluidic chip to generate and introduce droplets of an aqueous solution into the microfluidic chip. The droplets travelling in a network of chip channels may be captured in on-chip traps in a manner defined by hydrodynamic resistances of chip channels. A biological reaction may be performed on a droplet trapped on the microfluidic chip.

Abstract: The present invention relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions. The compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions in the medical, veterinary and agricultural fields.

Abstract: In one aspect, the disclosure relates to composite fibers having a structure comprising a core component and sheath component, wherein each of the core component and the sheath layer independently comprise a polymer and a disclosed cooling composition. In various further aspects, the present disclosure pertains to single-covered yarn comprising a core yarn comprising a disclosed composite fiber comprising a core component and a sheath component. In still further aspects, the present disclosure pertains to a fabric, such as a denim fabric, comprising a disclosed single-covered yarn. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: A microcapsule composition is provided, which contains a polyurea or polyurethane microcapsule, an alkylnaphthalenesulfonate formaldehyde condensate, and polyvinylpyrrolidone. Also disclosed is a process of preparing the microcapsule composition and a consumer product having such a microcapsule composition.

Abstract: A herbicidal composition comprising an aqueous suspension of microcapsules is provided. The microcapsules have a capsule wall of a porous condensate polymer, wherein the microcapsules contain a solution of clomazone in a solvent system comprising one or more non-edible oils. A method for preparing the composition comprises providing a water immiscible phase comprising clomazone, an isocyanate and optionally an ACD cross-linker, dissolved in a solvent system comprising a non-edible oil; providing an aqueous phase comprising one or more surfactants; combining the water immiscible phase and the aqueous phase to form a dispersion of the water immiscible phase in the aqueous phase; thereby forming microcapsules of polyurea containing droplets of the water immiscible phase; and curing the microcapsules.

Abstract: High strength, high integrity microcapsules containing a hydrophobic core material wherein said microcapsule walls are formed of copolymers of select monomers through a multistep oil-in-water emulsification polymerization process.

Abstract: The present invention relates to a regenerated cellulose fiber having a multi-limbed cross-section. The fiber according to the invention is characterized in that the cross-section is formed of at least two multi-limbed basic shapes (1?, 2?, 3?, 4?), which basic shapes are connected, in each case at least at one of their limb ends, to the limb end of another basic shape and the length of the connecting limb (12) resulting from the connection of the two limb ends is longer than the length of the shortest one of the other limbs by a factor of at least 1.5, preferably of from 1.5 to 2.0.

Abstract: The invention relates to stable dispersions, containing (a) 50 to 80% by weight of perfume oils, (b) 10 to 30% by weight of encapsulated fragrances, (c) 0.01 to 0.1% by weight of non-ionic polymers of the type of hydrophobically modified hydroxylalkyl guar compounds, with the proviso that the constituents together with water and optionally other typical auxiliary agents and additives add up to 100% by weight.

Abstract: A method includes coating a substrate to provide a flame resistant substrate. In an embodiment, the method includes exposing the substrate to a cationic solution to produce a cationic layer deposited on the substrate. The cationic solution comprises cationic materials. The cationic materials comprise a polymer, a colloidal particle, a nanoparticle, a nitrogen-rich molecule, a geopolymer, a carbon-based filler, or any combinations thereof. The method also includes agitating the substrate. The method further includes exposing the cationic layer to an anionic solution to produce an anionic layer deposited on the cationic layer to produce a layer comprising the anionic layer and the cationic layer. The anionic solution comprises a layerable material.

Abstract: According to various aspects and embodiments, core-shell particles and methods of making the same are disclosed. The core-shell particles may include a liquid metal core, at least one layer of inorganic material surrounding the liquid metal core, and at least one layer of organic material attached to the at least one layer of inorganic material.

Abstract: Novel lipid vesicle compositions comprising lipids derived from olive oil fatty acids known as olivates, methods of their preparation, and methods of their use in cosmetics, food, dermatologics, and pharmaceuticals.

Abstract: An object is to provide a formulation that includes a particle containing an active ingredient and a surfactant, and a base, and is more excellent in storage stability. For solution, a formulation including a particle containing an active ingredient and a surfactant, and a base, in which the surfactant is contained in a ratio of 5 to 100 parts by weight based on 1 part by weight of the active ingredient, is provided.

Abstract: To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer tissue, comprising a bacterium, and a microbead encapsulated with at least one drug, wherein biotin is bound to a surface of the bacterium and a surface of the microbead is coated with streptavidin.

Abstract: A quantum dot having core-shell structure, including a core formed of ZnOzS1-z of wurtzite crystal structure of hexagonal crystal system; a first shell covering the core, and formed of AlxGayIn1-x-yN of wurtzite crystal structure of hexagonal crystal system; and a second shell covering the first shell, and formed of ZnOvS1-v of wurtzite crystal structure of hexagonal crystal system. At least one of v, x, y, and z is not zero and is not one; differences between the lattice constants along a-axis of the core, the first shell and the second shell are not greater than 1%; and the core, the first shell and the second shell form band offset structure of type II.

Abstract: A novel diazirine-based biocompatible polymer that can be used as on-demand or tunable bioadhesive and applied across various clinically important surfaces. The biocompatible polymer comprises a single strand of repeating units and up to 5,000 photoreactive diazirine groups covalently attached to it. A bioadhesive composition comprises the polymer of the present invention and suitable solvents, surfactants, stabilizers, fillers and other additives. The composition may additionally contain metallic particles of size less than 50 micron made of rare earth elements and has UV or NIR transparency less than 1 optical density unit per 1 centimeter. The poly-diazirine surface grafted thin films can be used for minimally invasive surgeries.

Abstract: The invention provides a novel approach to controlled delivery of biomolecules (e.g., lipids and proteins) by employing novel amphiphilic polymers that are effective delivery vehicles. These unique amphiphilic polymers may be employed as controlled delivery vehicles or tissue engineering scaffolds wherein the delivery of lipophilic or amphiphilic bioactive molecules can be achieved. An amphiphilic biodegradable polymer platform is disclosed herein for the stable encapsulation and sustained release of biomolecules, such as S1P.

Abstract: More particularly, the present invention relates to a process for producing antimicrobial core-shell microcapsules with immobilized silver particles into and onto the shell. The latter can be used in home or personal care products for delivering a perfuming and malodor-countering effect. The microcapsules obtainable by such a process and the consumer products comprising these microcapsules are also objects of the invention.

Abstract: Disclosed are homogenized formulations that comprise microcapsules, wherein the microcapsules comprise an agglomeration of primary microcapsules and a loading substance, where each individual primary microcapsule has a primary shell, and the loading substance is encapsulated by the primary shell, and wherein the agglomeration is encapsulated by an outer shell. Also, disclosed are methods of making and using homogenized formulations by providing a pre-homogenized composition comprising one or more microcapsules and then homogenizing the composition. Some specific homogenization processes described are ultrasonic and pressure-based homogenizations.

Abstract: A capsule composition containing a capsule and a stabilizing agent. The capsule has an oil core containing an active material and a capsule wall encapsulating the oil core. The active material is a fragrance, a flavor, a malodor counteractant, or a combination thereof. The wall is formed of polyurea or polyurethane. The capsule composition has 20 ppm or greater of the stabilizing agent, which is a multi-functional amine, an amino acid, a polymer mixture, or a combination thereof. Also disclosed is a consumer product containing this capsule composition.

Abstract: We disclose a composition comprising an echogenic liposome (ELIP) having an exterior surface, an interior surface, and at least one bilayer comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, and a thrombolytic compound trapped by the ELIP. We also disclose a method of treating a medical condition in a patient characterized by a thrombus in the patient's vasculature, comprising administering to the patient the composition in an amount effective to reduce the size of the thrombus.

Abstract: A hollow polymer particle includes a structure body that contains a structure including (1) a core polymer formed by copolymerizing a monomer mixture (a) consisting of 20 to 60% by weight of an acid group-containing monomer and 80 to 40% by weight of another monomer that is copolymerizable with the acid group-containing monomer and (2) a shell polymer formed by copolymerizing a monomer mixture (b) consisting of 0 to 15% by weight of an acid group-containing monomer and 100 to 85% by weight of another monomer that is copolymerizable with the acid group-containing monomer so that the shell polymer substantially surrounding the core polymer. The structure body has at least one void formed by neutralization of at least one portion of an acid group contained in the core polymer. The hollow polymer particle is obtained by adding a preservative during a time period after formation of the core polymer and before formation of the shell polymer.

Abstract: There is disclosed method of killing nematodes comprising the step of applying an effective amount of a nematicidal composition comprising a terpene component and compositions suitable for use in the method. The terpene component is preferably in association with water, either as a solution or a suspension. An excipient may also be included, which is suitably hollow glucan particles which encapsulate the terpene component.

Abstract: The present invention refers to a cosmetic composition of the oil-in-glycol type comprising (a) at least one sucrose non-ionic surfactant or derivatives thereof, (b) at least one fatty alcohol, (c) at least one glycol and (d) at least one ingredient selected from aminoacid and/or peptide, as well as associated uses, products and methods. The composition of the invention is capable of restoring the cutaneous barrier, reorganizing the lipidic layer of the stratum corneum in orthorhombic, conceding hydration, renewal and cellular energization in the long run. In a particular embodiment, said composition can be used simultaneously as an emulsifying system for preparing cosmetic products, for example, in the preparation of creams, lotions, etc.

Abstract: Described herein are compositions comprising particles of poorly soluble drugs encapsulated by stabilizers. Further described are pharmaceutical compositions comprising such encapsulated compositions. Also described are methods of making such encapsulated particle compositions, and methods of making the corresponding pharmaceutical compositions. The encapsulated particle compositions described herein allow poorly soluble drugs to be administered with good bioavailability by routes that are non-invasive to patients, such as by oral administration.

Abstract: This invention reports ciprofloxacin (CIP)-encapsulated polymeric nanoparticles and its antibacterial potential with a variety of gram positive and gram negative pathogenic bacteria. CIP-encapsulated nanoparticles of diethylaminoethyl cellulose (DEA-EC) are prepared by the multiple emulsion solvent evaporation method. CIP-encapsulated nanoparticles showed superior effectiveness to inhibit the growth of bacteria in-vitro.

Abstract: The invention provides non-spherical resin particles with a novel shape capable of improving light diffusion, adhesion, oil absorption, and other properties, as well as a manufacturing method and use of the particles. Each non-spherical resin particle includes a concave portion and a convex portion formed in the concave portion, wherein the convex portion has a quasi-spherical surface. The method of manufacturing non-spherical resin particles involves a step of polymerizing 100 parts by weight of a first monomer mixture containing 77 to 99.99 parts by weight of a branched alkyl methacrylate, 0.01 to 3 parts by weight of a polyfunctional monomer, and 0 to 20 parts by weight of a monofunctional (meth)acrylate which is not a branched alkyl methacrylate, in the presence of 0.1 to 0.9 parts by weight of a chain transfer agent and 0 to 100 parts by weight of a (meth)acrylate polymer, to obtain resin particles.

Abstract: The present invention relates to a process for producing microcapsules with a polyurea wall, as well as to the microcapsules themselves and consumer products comprising these microcapsules. The process of the invention uses 3,5-diamino-1,2,4-triazole as a specific polyamine for forming the wall with the polyisocyanate.

Abstract: Controlled release oral dosage formulations containing calcium channel blocker and processes for preparation thereof, are provided for once a day treatment. The active agent is preferably a dihydropyridine calcium channel blocker, such as nisoldipine. In one embodiment, the formulation provides controlled release of micronized nisoldipine with one or more pH independent release controlling polymers. The controlled release matrix formulation is advantageous and can be prepared by a simple, economically viable process as compared to complex core-coat prior-art versions.

Abstract: An embodiment of the invention provides a method for forming microcapsules for electrophoresis display by forming microcapsules through a complex coacervation reaction between a sulfonated styrene maleic anhydride copolymer and gelatin, wherein a mass ratio of the sulfonated styrene maleic anhydride copolymer to the gelatin is 1:10˜10:1. The method of the embodiment of the invention not only can obtain microcapsules with good sealability and stability, but also can obtain microcapsules having evenly distributed particle sizes and low cost.