Microcapsule With Fluid Core (includes Liposome) Patents (Class 428/402.2)
  • Patent number: 10537503
    Abstract: A microcapsule composition is provided, which contains a polyurea or polyurethane microcapsule, an alkylnaphthalenesulfonate formaldehyde condensate, and polyvinylpyrrolidone. Also disclosed is a process of preparing the microcapsule composition and a consumer product having such a microcapsule composition.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: January 21, 2020
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Yabin Lei, Li Xu, John Brahms
  • Patent number: 10499639
    Abstract: A herbicidal composition comprising an aqueous suspension of microcapsules is provided. The microcapsules have a capsule wall of a porous condensate polymer, wherein the microcapsules contain a solution of clomazone in a solvent system comprising one or more non-edible oils. A method for preparing the composition comprises providing a water immiscible phase comprising clomazone, an isocyanate and optionally an ACD cross-linker, dissolved in a solvent system comprising a non-edible oil; providing an aqueous phase comprising one or more surfactants; combining the water immiscible phase and the aqueous phase to form a dispersion of the water immiscible phase in the aqueous phase; thereby forming microcapsules of polyurea containing droplets of the water immiscible phase; and curing the microcapsules.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: December 10, 2019
    Inventors: James Timothy Bristow, Yifan Wu
  • Patent number: 10485739
    Abstract: High strength, high integrity microcapsules containing a hydrophobic core material wherein said microcapsule walls are formed of copolymers of select monomers through a multistep oil-in-water emulsification polymerization process.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: November 26, 2019
    Assignee: ENCAPSYS LLC
    Inventors: Nianxi Yan, Biao Duan, Linsheng Feng
  • Patent number: 10435481
    Abstract: The present invention relates to a regenerated cellulose fiber having a multi-limbed cross-section. The fiber according to the invention is characterized in that the cross-section is formed of at least two multi-limbed basic shapes (1?, 2?, 3?, 4?), which basic shapes are connected, in each case at least at one of their limb ends, to the limb end of another basic shape and the length of the connecting limb (12) resulting from the connection of the two limb ends is longer than the length of the shortest one of the other limbs by a factor of at least 1.5, preferably of from 1.5 to 2.0.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: October 8, 2019
    Inventors: Ingo Bernt, Konrad Brunner, Matthew North, Reinhold Röthenbacher, Walter Roggenstein, Roland Scholz
  • Patent number: 10342748
    Abstract: The invention relates to stable dispersions, containing (a) 50 to 80% by weight of perfume oils, (b) 10 to 30% by weight of encapsulated fragrances, (c) 0.01 to 0.1% by weight of non-ionic polymers of the type of hydrophobically modified hydroxylalkyl guar compounds, with the proviso that the constituents together with water and optionally other typical auxiliary agents and additives add up to 100% by weight.
    Type: Grant
    Filed: February 14, 2016
    Date of Patent: July 9, 2019
    Assignee: Symrise AG
    Inventors: Jörg Dröge, Jörn Wiedemann
  • Patent number: 10343185
    Abstract: A method includes coating a substrate to provide a flame resistant substrate. In an embodiment, the method includes exposing the substrate to a cationic solution to produce a cationic layer deposited on the substrate. The cationic solution comprises cationic materials. The cationic materials comprise a polymer, a colloidal particle, a nanoparticle, a nitrogen-rich molecule, a geopolymer, a carbon-based filler, or any combinations thereof. The method also includes agitating the substrate. The method further includes exposing the cationic layer to an anionic solution to produce an anionic layer deposited on the cationic layer to produce a layer comprising the anionic layer and the cationic layer. The anionic solution comprises a layerable material.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: July 9, 2019
    Assignee: The Texas A&M University System
    Inventors: Jaime C. Grunlan, Tyler C. Guin
  • Patent number: 10293325
    Abstract: According to various aspects and embodiments, core-shell particles and methods of making the same are disclosed. The core-shell particles may include a liquid metal core, at least one layer of inorganic material surrounding the liquid metal core, and at least one layer of organic material attached to the at least one layer of inorganic material.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: May 21, 2019
    Inventors: Martin Thuo, Ian Tevis
  • Patent number: 10251839
    Abstract: Novel lipid vesicle compositions comprising lipids derived from olive oil fatty acids known as olivates, methods of their preparation, and methods of their use in cosmetics, food, dermatologics, and pharmaceuticals.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: April 9, 2019
    Assignee: IGI Laboratories, Inc.
    Inventors: Nadya Lawrence, Rosemarie Lorenzo
  • Patent number: 10130710
    Abstract: An object is to provide a formulation that includes a particle containing an active ingredient and a surfactant, and a base, and is more excellent in storage stability. For solution, a formulation including a particle containing an active ingredient and a surfactant, and a base, in which the surfactant is contained in a ratio of 5 to 100 parts by weight based on 1 part by weight of the active ingredient, is provided.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: November 20, 2018
    Inventors: Takayuki Akamine, Kazushi Itou, Saori Tone, Yoshiko Abe
  • Patent number: 10034903
    Abstract: To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer tissue, comprising a bacterium, and a microbead encapsulated with at least one drug, wherein biotin is bound to a surface of the bacterium and a surface of the microbead is coated with streptavidin.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: July 31, 2018
    Inventors: Suk Ho Park, Jong Oh Park, Sung Jun Park, Seong Young Ko, Jung Joon Min, Seung Hwan Park
  • Patent number: 10032955
    Abstract: A quantum dot having core-shell structure, including a core formed of ZnOzS1-z of wurtzite crystal structure of hexagonal crystal system; a first shell covering the core, and formed of AlxGayIn1-x-yN of wurtzite crystal structure of hexagonal crystal system; and a second shell covering the first shell, and formed of ZnOvS1-v of wurtzite crystal structure of hexagonal crystal system. At least one of v, x, y, and z is not zero and is not one; differences between the lattice constants along a-axis of the core, the first shell and the second shell are not greater than 1%; and the core, the first shell and the second shell form band offset structure of type II.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: July 24, 2018
    Inventors: Takuya Kazama, Wataru Tamura, Yasuyuki Miyake
  • Patent number: 10005936
    Abstract: A novel diazirine-based biocompatible polymer that can be used as on-demand or tunable bioadhesive and applied across various clinically important surfaces. The biocompatible polymer comprises a single strand of repeating units and up to 5,000 photoreactive diazirine groups covalently attached to it. A bioadhesive composition comprises the polymer of the present invention and suitable solvents, surfactants, stabilizers, fillers and other additives. The composition may additionally contain metallic particles of size less than 50 micron made of rare earth elements and has UV or NIR transparency less than 1 optical density unit per 1 centimeter. The poly-diazirine surface grafted thin films can be used for minimally invasive surgeries.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: June 26, 2018
    Inventors: W. J. Terry Steele, Vladislav Papper, Robert S. Marks
  • Patent number: 9999704
    Abstract: The invention provides a novel approach to controlled delivery of biomolecules (e.g., lipids and proteins) by employing novel amphiphilic polymers that are effective delivery vehicles. These unique amphiphilic polymers may be employed as controlled delivery vehicles or tissue engineering scaffolds wherein the delivery of lipophilic or amphiphilic bioactive molecules can be achieved. An amphiphilic biodegradable polymer platform is disclosed herein for the stable encapsulation and sustained release of biomolecules, such as S1P.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: June 19, 2018
    Assignee: University of Massachusetts
    Inventors: Jie Song, Jing Zhang
  • Patent number: 9968120
    Abstract: Disclosed are homogenized formulations that comprise microcapsules, wherein the microcapsules comprise an agglomeration of primary microcapsules and a loading substance, where each individual primary microcapsule has a primary shell, and the loading substance is encapsulated by the primary shell, and wherein the agglomeration is encapsulated by an outer shell. Also, disclosed are methods of making and using homogenized formulations by providing a pre-homogenized composition comprising one or more microcapsules and then homogenizing the composition. Some specific homogenization processes described are ultrasonic and pressure-based homogenizations.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: May 15, 2018
    Inventors: Jonathan Michael Curtis, Wei Zhang, Sharon Ann Spurvey, Suzelle Rejeanne Robert
  • Patent number: 9968096
    Abstract: More particularly, the present invention relates to a process for producing antimicrobial core-shell microcapsules with immobilized silver particles into and onto the shell. The latter can be used in home or personal care products for delivering a perfuming and malodor-countering effect. The microcapsules obtainable by such a process and the consumer products comprising these microcapsules are also objects of the invention.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: May 15, 2018
    Assignee: Firmenich SA
    Inventors: Huda Jerri, Marlène Jacquemond, Brian MacDougall
  • Patent number: 9816059
    Abstract: A capsule composition containing a capsule and a stabilizing agent. The capsule has an oil core containing an active material and a capsule wall encapsulating the oil core. The active material is a fragrance, a flavor, a malodor counteractant, or a combination thereof. The wall is formed of polyurea or polyurethane. The capsule composition has 20 ppm or greater of the stabilizing agent, which is a multi-functional amine, an amino acid, a polymer mixture, or a combination thereof. Also disclosed is a consumer product containing this capsule composition.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: November 14, 2017
    Inventors: Volkert de Villeneuve, Djurre Sijbren Postma, Elizabeth Geertruida Maria Brundel, John Brahms, Li Xu, Joan G. L. Pluter, Laura French, Yabin Lei, Lewis Michael Popplewell, Xiao Huang
  • Patent number: 9814672
    Abstract: We disclose a composition comprising an echogenic liposome (ELIP) having an exterior surface, an interior surface, and at least one bilayer comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, and a thrombolytic compound trapped by the ELIP. We also disclose a method of treating a medical condition in a patient characterized by a thrombus in the patient's vasculature, comprising administering to the patient the composition in an amount effective to reduce the size of the thrombus.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: November 14, 2017
    Inventors: Susan T. Laing, Shaoling Huang, David D. McPherson, Christy K. Holland, Melvin E. Klegerman
  • Patent number: 9714311
    Abstract: A hollow polymer particle includes a structure body that contains a structure including (1) a core polymer formed by copolymerizing a monomer mixture (a) consisting of 20 to 60% by weight of an acid group-containing monomer and 80 to 40% by weight of another monomer that is copolymerizable with the acid group-containing monomer and (2) a shell polymer formed by copolymerizing a monomer mixture (b) consisting of 0 to 15% by weight of an acid group-containing monomer and 100 to 85% by weight of another monomer that is copolymerizable with the acid group-containing monomer so that the shell polymer substantially surrounding the core polymer. The structure body has at least one void formed by neutralization of at least one portion of an acid group contained in the core polymer. The hollow polymer particle is obtained by adding a preservative during a time period after formation of the core polymer and before formation of the shell polymer.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: July 25, 2017
    Inventor: Atsushi Yamaguchi
  • Patent number: 9655832
    Abstract: The present invention refers to a cosmetic composition of the oil-in-glycol type comprising (a) at least one sucrose non-ionic surfactant or derivatives thereof, (b) at least one fatty alcohol, (c) at least one glycol and (d) at least one ingredient selected from aminoacid and/or peptide, as well as associated uses, products and methods. The composition of the invention is capable of restoring the cutaneous barrier, reorganizing the lipidic layer of the stratum corneum in orthorhombic, conceding hydration, renewal and cellular energization in the long run. In a particular embodiment, said composition can be used simultaneously as an emulsifying system for preparing cosmetic products, for example, in the preparation of creams, lotions, etc.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: May 23, 2017
    Inventors: Alexandra Bazito, Maria Regina Bartuccio Raponi, Nelson Luis Perassinoto, Liliana Calore Brenner
  • Patent number: 9655360
    Abstract: There is disclosed method of killing nematodes comprising the step of applying an effective amount of a nematicidal composition comprising a terpene component and compositions suitable for use in the method. The terpene component is preferably in association with water, either as a solution or a suspension. An excipient may also be included, which is suitably hollow glucan particles which encapsulate the terpene component.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: May 23, 2017
    Assignee: Eden Research PLC
    Inventors: Lanny Franklin, Gary Ostroff, Elizabeth Cloud, Lanna Franklin Rudeseal
  • Patent number: 9555009
    Abstract: This invention reports ciprofloxacin (CIP)-encapsulated polymeric nanoparticles and its antibacterial potential with a variety of gram positive and gram negative pathogenic bacteria. CIP-encapsulated nanoparticles of diethylaminoethyl cellulose (DEA-EC) are prepared by the multiple emulsion solvent evaporation method. CIP-encapsulated nanoparticles showed superior effectiveness to inhibit the growth of bacteria in-vitro.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: January 31, 2017
    Inventors: Muhammad Akhyar Farrukh, Muhammad Rehan Gul, Muhammad Khaleeq-ur- Rahman
  • Patent number: 9554996
    Abstract: Described herein are compositions comprising particles of poorly soluble drugs encapsulated by stabilizers. Further described are pharmaceutical compositions comprising such encapsulated compositions. Also described are methods of making such encapsulated particle compositions, and methods of making the corresponding pharmaceutical compositions. The encapsulated particle compositions described herein allow poorly soluble drugs to be administered with good bioavailability by routes that are non-invasive to patients, such as by oral administration.
    Type: Grant
    Filed: January 15, 2013
    Date of Patent: January 31, 2017
    Inventor: James David Talton
  • Patent number: 9527969
    Abstract: The invention provides non-spherical resin particles with a novel shape capable of improving light diffusion, adhesion, oil absorption, and other properties, as well as a manufacturing method and use of the particles. Each non-spherical resin particle includes a concave portion and a convex portion formed in the concave portion, wherein the convex portion has a quasi-spherical surface. The method of manufacturing non-spherical resin particles involves a step of polymerizing 100 parts by weight of a first monomer mixture containing 77 to 99.99 parts by weight of a branched alkyl methacrylate, 0.01 to 3 parts by weight of a polyfunctional monomer, and 0 to 20 parts by weight of a monofunctional (meth)acrylate which is not a branched alkyl methacrylate, in the presence of 0.1 to 0.9 parts by weight of a chain transfer agent and 0 to 100 parts by weight of a (meth)acrylate polymer, to obtain resin particles.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: December 27, 2016
    Assignee: Sekisui Plastics Co., Ltd.
    Inventors: Masaaki Nakamura, Ryosuke Harada
  • Patent number: 9499769
    Abstract: The present invention relates to a process for producing microcapsules with a polyurea wall, as well as to the microcapsules themselves and consumer products comprising these microcapsules. The process of the invention uses 3,5-diamino-1,2,4-triazole as a specific polyamine for forming the wall with the polyisocyanate.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: November 22, 2016
    Assignee: Firmenich SA
    Inventors: Claudie Bellouard-Drevet, Damien Berthier, Marlene Jacquemond, Nicolas Pichon, Sonia Godefroy, Arnaud Struillou, Magali Lateulere, Estelle Rassat
  • Patent number: 9480681
    Abstract: Controlled release oral dosage formulations containing calcium channel blocker and processes for preparation thereof, are provided for once a day treatment. The active agent is preferably a dihydropyridine calcium channel blocker, such as nisoldipine. In one embodiment, the formulation provides controlled release of micronized nisoldipine with one or more pH independent release controlling polymers. The controlled release matrix formulation is advantageous and can be prepared by a simple, economically viable process as compared to complex core-coat prior-art versions.
    Type: Grant
    Filed: September 5, 2012
    Date of Patent: November 1, 2016
    Assignee: Emcure Pharmaceuticals Limited
    Inventors: Jitendra Mohansingh Baweja, Manoj Kumar Thottasseri, Sandip Tanaji Salunkhe, Mukund Keshav Gurjar, Samit Satish Mehta
  • Patent number: 9477132
    Abstract: An embodiment of the invention provides a method for forming microcapsules for electrophoresis display by forming microcapsules through a complex coacervation reaction between a sulfonated styrene maleic anhydride copolymer and gelatin, wherein a mass ratio of the sulfonated styrene maleic anhydride copolymer to the gelatin is 1:10˜10:1. The method of the embodiment of the invention not only can obtain microcapsules with good sealability and stability, but also can obtain microcapsules having evenly distributed particle sizes and low cost.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: October 25, 2016
    Inventors: Wenwen Sun, Chuanxiang Xu
  • Patent number: 9439416
    Abstract: The present invention relates to compositions comprising terpenes which are particularly suitable for treating plant infections, to methods of making such compositions, and to methods of using them. The present invention also relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions; such compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions in the medical, veterinary and agricultural fields. In particular, the terpenes disclosed are thymol, eugenol, geraniol, citral and L-carvone.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: September 13, 2016
    Assignee: Eden Research PLC
    Inventors: Lanny Franklin, Elizabeth Cloud, Lanna Knapp, Gary Ostroff
  • Patent number: 9301544
    Abstract: The present disclosure describes methods of obtaining and/or deriving proteins from plants of the Nicotiana species and methods for incorporation of such proteins into various products. For example, a method for obtaining a protein-enriched material from a plant of the Nicotiana species or portion thereof is provided, comprising: extracting one or more proteins from the plant material into a solvent to form a liquid protein-containing extract; separating a solid extracted plant material from the liquid protein-containing extract; clarifying the liquid protein-containing extract to form a clarified protein-containing extract and a solids fraction; and treating the clarified protein-containing extract so as to provide a protein-enriched material comprising at least about 60% protein by weight.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 5, 2016
    Assignee: R.J. Reynolds Tobacco Company
    Inventors: John-Paul Mua, Kyle Ford, Leigh Ann Blevins Joyce, Margarette Elisa Lovette, Joshua D. Morton, Leigh Hagan, Barry Bratcher, Samuel Mark Debusk
  • Patent number: 9283154
    Abstract: A method for making a composite particulate comprised of a colorant portion and a clear thermoplastic portion and cosmetic compositions containing the composite particulate.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: March 15, 2016
    Assignee: ELC Management LLC
    Inventors: Isaac David Cohen, Phillip Cummins, Milan Franz Sojka, David Walter Culhane, Christina G. Fthenakis, Jennifer L. Sobel, John Dudley Dreher, Yelena Mikhaylova
  • Patent number: 9241912
    Abstract: The present invention relates to microcapsules comprising a polyurea shell and a core, which contains a pesticide, a water-immiscible solvent A and at least 5 wt % of an aprotic, polar solvent B, which has a solubility in water from 0.5 to 20 g/l at 20° C., based on the total weight of the solvents in the core. It further relates to microcapsules comprising a shell and a core, which contains a pesticide and 2-heptanone; to a method for preparing said microcapsules; to an aqueous composition comprising said microcapsules; and to a method for controlling phytopathogenic fungi and/or undesired plant growth and/or undesired attack by insects or mites and/or for regulating the growth of plants, with said microcapsules.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: January 26, 2016
    Assignee: BASF SE
    Inventors: Claude Taranta, Thomas Bork, Tina Schroeder-Grimonpont, Britta Katz, Tatjana Sikuljak, Simon Nord, Juergen Distler, Richard A. Warriner, Daniel Bihlmeyer, James Thomas Wofford
  • Patent number: 9243130
    Abstract: The invention relates to metal oxide or semimetal oxide nanoparticles having an average particle size of from 2 to 250 nm, characterized in that the nanoparticles have at least two different, free-radically polymerizable groups on the surface. The invention further relates to nanocomposites produced from such nanoparticles and also processes for producing them.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: January 26, 2016
    Assignee: Evonik Nanoresins GmbH
    Inventors: Klaus Langerbeins, Uwe Dietrich Kühner, Werner Siol
  • Patent number: 9211235
    Abstract: The present invention relates in a first aspect to an adhesion material for use in an individual containing encapsulated phase-change material. In particular, the adhesion material is for cosmetical or medicinal use in the body of an individual. The adhesion material contains encapsulated phase-change material having preferably a phase transition temperature above 40° C., like above 55° C. The adhesion material is particularly useful for adhering elements, like dental restorations, e.g. crowns or bridge, or brackets on elements in the body of an individual, like teeth or implants. That is, the adhesion material is particularly useful for adhering material in dental applications. In another aspect, a method is provided allowing removing a bracket, a crown or bridge, from implants, abutments or teeth. Furthermore, dental implant restoration systems and kits for permanent fixation of implants allowing improved removal thereof are provided.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: December 15, 2015
    Assignee: Rheinisch-Westfaelische Technisch Hochschule Aachen
    Inventors: Stefan Wolfart, Andrij Pich
  • Patent number: 9107824
    Abstract: One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml. Another aspect of the invention relates to lipid-complexed platinum compound compositions where the concentration of the platinum compound is greater than about 1.2 mg/ml.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: August 18, 2015
    Assignee: Insmed Incorporated
    Inventors: Frank G. Pilkiewicz, Roman Perez-Soler, Yiyu Zou, Walter R. Perkins, Jin K. Lee, Vladimir Malinin
  • Patent number: 9067395
    Abstract: A low temperature curable epoxy tape is provided that can be useful as a semi-structural adhesive tape in the automotive, aerospace, and electronics industries to form metal-to-metal and metal-to-plastic bonds. The provided epoxy tape includes a curative layer. The curative layer includes a scrim, a binder layer at least partially enclosing the scrim, and a latent curative dispersed in the binder layer. The curative layer is coated and then dried of solvent. Then an epoxy layer is laminated to a top and a bottom of the curative layer. The epoxy tape is placed between two parts being bonded together and then heated to temperatures of bottom up to about 110° C. to activate and disperse the active curative. A semi-structural bond is formed. Also, a method of making the epoxy tape is provided.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: June 30, 2015
    Assignee: 3M Innovative Properties Company
    Inventors: David J. Plaut, Sean M. Tsuji, Chin Teong Ong, Siang Kwang Lee
  • Patent number: 9056058
    Abstract: Disclosed are microcapsules and methods for preparing and using them, as well as methods for improving various properties of microcapsules like impermeability.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: June 16, 2015
    Assignee: DSM Nutritional Products
    Inventors: Jin Yulai, Colin James Barrow, Wei Zhang, Cuie Yan, Jonathan Michael Curtis, Shawn Moulton, Nancy Beatrice Djogbenou, Lesek Alexa Demont
  • Patent number: 9056302
    Abstract: The present invention relates to microcapsules comprising a capsule core and a capsule wall, obtainable by a process comprising the free-radical polymerization of an oil-in-water emulsion which comprises the following constituents: 30 to 90% by weight based on the total weight of the monomers of one or more monomers (monomers I) from the group comprising C1-C24-alkyl esters of acrylic acid and/or methacrylic acid, acrylic acid, methacrylic acid, maleic acid, fumaric acid and itaconic acid 10 to 70% by weight based on the total weight of the monomers of one or more ethylenically unsaturated crosslinkers (monomers II), where at least 10% by weight, based on the total weight of the monomers I, II and III, is a highly branched polymeric crosslinker, 0 to 30% by weight based on the total weight of the monomers of one or more monounsaturated monomers (monomer III), which are different from the monomers I, and a hydrophobic core material, to a process for their preparation and to their use.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: June 16, 2015
    Assignee: BASF SE
    Inventors: Marc Rudolf Jung, Francisco Javier Lopez Villanueva, Tina Schroeder-Grimonpont, Monika Haberecht, Bernd Bruchmann
  • Patent number: 9040157
    Abstract: In one aspect, hollow nanoparticles are described herein. In some embodiments, a hollow nanoparticle comprises a metal shell and a cavity substantially defined by the shell, wherein the shell has a thickness greater than or equal to about 5 nm and the cavity has a curved surface. In another aspect, methods of making hollow nanoparticles are described herein. In some embodiments, a method of making hollow nanoparticles comprises forming a plurality of gas bubbles and forming a shell on the surface of at least one of the plurality of gas bubbles, wherein at least one of the gas bubbles is electrochemically generated. In another aspect, composite particles are described herein. In some embodiments, a composite particle comprises at least one nanoparticle and a polycrystalline metal shell substantially encapsulating at least one nanoparticle, wherein at least one surface of at least one nanoparticle is not in contact with the shell.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: May 26, 2015
    Inventors: Yaowu Hao, Chien-Wen Huang
  • Patent number: 9028965
    Abstract: Disclosed are heat storage microcapsules encapsulating a water-soluble heat storage material stably and certainly, heat storage microcapsules with high durability which prevent phase separation of an inorganic salt hydrate latent heat storage material, heat storage microcapsules which prevent supercooling of a latent heat storage material to exhibit stable heat history and a manufacturing method thereof. The heat storage microcapsules comprise a core covered with a shell, wherein the core contains (a) at least one water-soluble latent heat storage material selected from a salt hydrate and a sugar alcohol and (b) a polymer derived from a water-soluble monomer mixture of a water-soluble monofunctional monomer and a water-soluble multifunctional monomer, and the shell is composed of a hydrophobic resin.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: May 12, 2015
    Assignee: Konica Minolta Business Technologies, Inc.
    Inventors: Mikio Kouyama, Ken Ohmura
  • Patent number: 9005494
    Abstract: Prior art processes for producing protein-based capsules (for example, capsules for use in electrophoretic media) tend to be wasteful because they produce many capsules outside the desired size range, which is typically about 20 to 50 ?m. Capsule size distribution and yields can be improved by either (a) emulsifying a water-immiscible phase in a preformed coacervate of the protein; or (b) using a limited coalescence process with colloidal alumina as the surface-active particulate material.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: April 14, 2015
    Assignee: E Ink Corporation
    Inventors: Peter J. Valianatos, Rajesh Chebiyam, Jeremy J. Manning, Michael L. Steiner, Thomas H. Whitesides, Michael D. Walls
  • Patent number: 8986838
    Abstract: Elastic and ultra-lightweight hollow carbon fine particles and a method for producing such hollow carbon fine particles are to be provided. In the method, fine droplets are formed from a mixed solution containing a water soluble organic substance and lithium carbonate; composite fine particles of the water soluble organic substance and the lithium carbonate are prepared by drying the fine droplets formed from the mixed solution; and the composite fine particles are decomposed at a temperature in a range of 500° C. to 900° C.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: March 24, 2015
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Katsumi Kamegawa, Tsuyoshi Sakaki, Kinya Sakanishi, Masaya Kodama, Keiko Nishikubo, Yoshio Adachi
  • Patent number: 8968872
    Abstract: Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be prepared by providing an aqueous mixture of a loading substance and a shell material, adjusting pH, temperature, concentration and/or mixing speed to form primary shells of shell material around the loading substance and cooling the aqueous mixture until the primary shells agglomerate and an outer shell of shell material forms around the agglomeration. Such microcapsules are useful for storing a substance and for delivering the substance to a desired environment.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: March 3, 2015
    Assignee: DSM Nutritional Products AG
    Inventor: Nianxi Yan
  • Patent number: 8957122
    Abstract: A thermoplastic molding composition is provided, which comprises A) from 30 to 90% by weight of at least one thermoplastic polymer, B) from 10 to 70% by weight of microcapsules with a capsule core made of latent-heat-accumulator material and a polymer as capsule wall, where the latent-heat-accumulator material has its solid/liquid phase transition in the temperature range from ?20° C. to 120° C.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: February 17, 2015
    Assignee: BASF SE
    Inventors: Stephan Altmann, Dirk Opfermann, Tina Schroeder-Grimonpont, Marco Schmidt
  • Patent number: 8951570
    Abstract: An extrusion process comprises extruding a material that is flowable when heated and passing the extrudate thus formed through a nozzle 10 to shape the extrudate into a plurality of substantially uniformly shaped elements such as minispheres or minicapsules.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: February 10, 2015
    Assignee: Sigmoid Pharma Limited
    Inventor: Ivan Coulter
  • Patent number: 8951639
    Abstract: A method of making capsules includes forming a mixture including a core liquid, a polyurethane precursor system, a first component of a two-component poly(urea-formaldehyde) precursor system, and a solvent. The method further includes emulsifying the mixture, adding a second component of the two-component poly(urea-formaldehyde) precursor system to the emulsified mixture, and maintaining the emulsified mixture at a temperature and for a time sufficient to form a plurality of capsules that encapsulate at least a portion of the core liquid. The capsules made by the method may include a polymerizer in the capsules, where the capsules have an inner capsule wall including a polyurethane, and an outer capsule wall including a poly(urea-formaldehyde). The capsules may include in the solid polymer matrix of a composite material.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: February 10, 2015
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Scott R. White, Jeffrey S. Moore, Nancy R. Sottos, Benjamin J. Blaiszik, Mary M. Caruso, Christian L. Mangun
  • Patent number: 8951542
    Abstract: The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: February 10, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Jaehyun Moon
  • Patent number: 8945504
    Abstract: The present invention relates to nano structures of metal oxides having a nanostructured shell (or wall), and an internal space or void. Nanostructures may be nanoparticles, nanorod/belts/arrays, nanotubes, nanodisks, nanoboxes, hollow nanospheres, and mesoporous structures, among other nanostructures. The nanostructures are composed of polycrystalline metal, oxides such as SnO2. The nanostructures may have concentric walls which surround the internal space of cavity. There may be two or more concentric shells or walls. The internal space may contain a core such ferric oxides or other materials which have functional properties. The invention also provides for a novel, inexpensive, high-yield method for mass production of hollow metal oxide nanostructures. The method may be template free or contain a template such as silica. The nanostructures prepared by the methods of the invention provide for improved cycling performance when tested using rechargeable lithium-ion batteries.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: February 3, 2015
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Lynden A. Archer, Xiong Wen Lou
  • Patent number: 8940394
    Abstract: Methods of preparing molecularly imprinted polymers are provided. In one embodiment, a method comprises providing a solution comprising a template molecule; and forming a product comprising calcium alginate in the presence of the template molecule so that the template molecule is imprinted in the product.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: January 27, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Nicholas A. Peppas, Edgar Perez-Herrero
  • Patent number: 8932714
    Abstract: A method for controlling a particle diameter and a particle diameter distribution of emulsion particles during manufacturing of an emulsion dispersion is provided. The method includes causing two or more types of liquids substantially immiscible with each other to continuously and sequentially pass through net bodies. The net bodies are disposed in a cylindrical flow passage at intervals of 5 to 200 mm, and the number of the net bodies is more than 50 and 200 or less. Each of the net bodies is equivalent to a gauze having a mesh number of 35 mesh to 4000 mesh in accordance with an ASTM standard and has a surface that intersects the direction of the flow passage. An emulsification apparatus used for the method includes a feed pump for feeding two or more types of liquids substantially immiscible with each other; and a cylindrical flow passage to which the two or more types of liquids fed by the feed pump are delivered.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: January 13, 2015
    Assignee: Nippon Oil Corporation
    Inventors: Toshikatsu Shoko, Yasuo Togami, Akira Takagi, Hideko Hayashi
  • Patent number: 8932706
    Abstract: A laminate including a plurality of layers, wherein one of the layers is a heat-activatable expandable layer including a thermally expandable composition. The heat-activatable expandable layer includes a plurality of microcapsules containing the thermally expandable composition. This thermally expandable composition includes an easily volatilizable hydrocarbon, and a binder resin. When subjected to high temperatures during the process of applying a label, the microcapsules rupture and the thermally expandable composition “foams,” which can be used to provide a texture to the label, and can raise or surround the graphics of the label.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: January 13, 2015
    Assignee: Multi-Color Corporation
    Inventors: Jean-Paul Laprade, Philip J. Albenice, Jean Donatelli, John W. Geurtsen
  • Publication number: 20140356289
    Abstract: The invention provides a droplet encapsulate comprising: a drop of a hydrophobic medium; a peripheral layer of non-polymeric amphipathic molecules around the surface of the drop; and an aqueous droplet within the peripheral layer, the aqueous droplet comprising: (a) an aqueous medium and (b) an outer layer of non-polymeric amphipathic molecules around the surface of the aqueous medium. The invention also provides processes for preparing the droplet encapsulates. Various uses of the droplet encapsulates are also described, including their use as drug delivery vehicles, in synthetic biology, and in the study of membrane proteins.
    Type: Application
    Filed: November 2, 2012
    Publication date: December 4, 2014
    Inventors: John Hagan Pryce Bayley, Andrew Heron, Gabriel Villar