Microcapsule With Fluid Core (includes Liposome) Patents (Class 428/402.2)
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Patent number: 6919685Abstract: This invention comprises the use of microspheres containing ionizable gas in a gas discharge (plasma) display, photons for the gas discharge within a microsphere exciting a phosphor such that the phosphor emits wavelengths in both the visible or invisible spectrum. The invention is described in detail hereinafter with reference to an AC gas discharge (plasma) display.Type: GrantFiled: September 24, 2002Date of Patent: July 19, 2005Assignee: Imaging Systems Technology INCInventors: Timothy M. Henderson, Donald K. Wedding
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Patent number: 6913828Abstract: Process for making metallic microcylinders from pre-treated diacetylenic lipid tubules which includes placing the tubules into an electroless plating bath containing a metal plating reagent, depositing by electroless plating on the surfaces of the tubules enough of a metal to make the tubules electrically conducting, separating the tubules from the plating bath, treating the tubules to remove the lipid and form the metal microcylinders, washing and drying the microcylinders to produce the metal microcylinders having aspect radio of about 12, weight average length of about 20?, weight average outside diameter of about 1.5?, and weight average wall thickness of about a quarter of one micron.Type: GrantFiled: March 5, 2002Date of Patent: July 5, 2005Assignee: The United States of America as represented by the Secretary of the NavyInventor: Dan Zabetakis
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Patent number: 6905766Abstract: The present invention provides novel encapsulation compositions and methods. In particular, the invention relates to fluorescent capsule compositions, which consists of a layer of a polymer shell enclosing one or more fluorescent materials such as fluorescent microspheres and which are capable of emitting at least two distinct fluorescent signals. Also provided are methods for their preparation. The compositions and methods of this invention are useful in a variety of applications, including preparation of multiplexed arrays for industrial, chemical, immunological, and genetic manipulation and analysis especially as related but not limited to flow cytometry.Type: GrantFiled: January 31, 2003Date of Patent: June 14, 2005Assignee: Luminex CorporationInventor: Don J. Chandler
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Patent number: 6887507Abstract: A membrane structure employing a structure in which a lipid membrane is held by a hydrophilic polymer. The hydrophilic polymer layer contains an aqueous phase. There are functional molecules distributed selectively throughout each layer. The membrane structure is adaptable to applications as a separating agent, filler or delivery agent by performing physical and chemical operations.Type: GrantFiled: December 7, 1999Date of Patent: May 3, 2005Assignee: Canon Kabushiki KaishaInventors: Tsuyoshi Nomoto, Yasuko Tomida, Junji Ohyama, Tomoko Maruyama
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Patent number: 6881482Abstract: Methods of making microcapsules and microcapsules comprising a core material and a shell material with substantially different dielectric constants and dissipation factors. Exposure to appropriate electromagnetic energy selectively (a) heats the core material with the higher dielectric constant and dissipation factor, directly or indirectly fusing the shell material and forming microcapsules, or (b) hardens polymerized shell material, which has a high dielectric constant and dissipation factor.Type: GrantFiled: August 16, 2002Date of Patent: April 19, 2005Assignee: Southwest Research InstituteInventor: Niraj Vasisht
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Patent number: 6866838Abstract: The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting of an organic phase and inorganic nanoparticles, distributed inside the organic phase, and a skin consisting of at least a hydrophilic polymer derived from the polymerisation of at least one water soluble monomer, in particular N-alkylacrylamide or a N—N-dialkylacrylamide; conjugates derived from said nanospheres; their preparation methods and their uses.Type: GrantFiled: November 6, 2000Date of Patent: March 15, 2005Assignees: Bio Merieux, Centre National de la Recherche ScientifiqueInventors: Olivier Mondain-Monval, Abdelhamid Elaissari, Eric Bosc, Christian Pichot, Bernard Mandrand, Jérôme Bibette
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Patent number: 6858225Abstract: Methods for the preparation of a lipid-nucleic acid composition are provided. According to the methods, a mixture of lipids containing a protonatable or deprotonatable lipid, for example an amino lipid and a lipid such as a PEG- or Polyamide oligomer-modified lipid is combined with a buffered aqueous solution of a charged therapeutic agent, for example polyanionic nucleic acids, to produce particles in which the therapeutic agent is encapsulated in a lipid vesicle. Surface charges on the lipid particles are at least partially neutralized to provide surface-neutralized lipid-encapsulated compositions of the therapeutic agents. The method permits the preparation of compositions with high ratios of therapeutic agent to lipid and with encapsulation efficiencies in excess of 50%.Type: GrantFiled: June 29, 2001Date of Patent: February 22, 2005Assignee: Inex Pharmaceuticals CorporationInventors: Sean C. Semple, Sandra K. Klimuk, Troy Harasym, Michael J. Hope, Steven M. Ansell, Pieter Cullis, Peter Scherrer, Dan Debeyer
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Patent number: 6855422Abstract: The invention relates to a multi-component fiber having enhanced reversible thermal properties and methods of manufacturing thereof. The multi-component fiber comprises a fiber body formed from a plurality of elongated members, at least one of the elongated members comprising a temperature regulating material dispersed therein. The temperature regulating material comprises a phase change material. The multi-component fiber may be formed via a melt spinning process or a solution spinning process and may be used or incorporated in various products where a thermal regulating property is desired. For example, the multi-component fiber may be used in textiles, apparel, footwear, medical products, containers and packagings, buildings, appliances, and other products.Type: GrantFiled: January 15, 2002Date of Patent: February 15, 2005Inventors: Monte C. Magill, Mark H. Hartmann, Jeffrey S. Haggard
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Patent number: 6855277Abstract: A new method of producing liposomes is described using an in-line mixing system. The liposomes produced by this method find utility in numerous therapeutic applications.Type: GrantFiled: November 15, 2002Date of Patent: February 15, 2005Assignee: Optime Therapeutics, Inc.Inventors: Martin T. Baker, William A. Heriot
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Patent number: 6843942Abstract: The invention relates to a device for producing lipid vesicles, which is equipped with a line (1) for transporting a polar liquid phase, with a line (2) for transporting an organic liquid phase containing lipids, with a collecting receptacle (7) for accommodating produced lipid vesicles, and with means for conveying the liquid phases through lines (1) and (2). At at least one location, the outer side of line (1) forms a common contact surface with line (2) inside of which a common opening (3) is provided that permits the flow of liquid and joins the inside of line (2) to the inside of line (1). Lines (1) and (2) do not contain agitating or dispersing aids in the area of the opening (3).Type: GrantFiled: October 31, 2001Date of Patent: January 18, 2005Assignee: Polymun Scientific Immunobilogische Forschung GmbHInventors: Hermann Katinger, Karola Vorauer-Uhl, Andreas Wagner, Guenter Kreismayr
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Patent number: 6841509Abstract: A carbon nanocapsule supported catalysts. At least one kind of catalytic metal particle is deposited to a carbon nanocapsule, wherein the carbon nanocapsule has the following formula: F(?M)n, in which F is the carbon nanocapsule, M is the catalytic metal particle, and n is the number of the catalytic metal particle. By applying the carbon nanocapsule as a catalyst support, the catalytic behavior of the catalytic metal particle is specialized, the dispersion is improved, and the catalytic effect is enhanced.Type: GrantFiled: November 20, 2003Date of Patent: January 11, 2005Assignee: Industrial Technology Research InstituteInventors: Gan-Lin Hwang, Chao-Kang Chang
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Patent number: 6841221Abstract: A process for making a textured coating on a substrate and compositions for such coatings are disclosed wherein coating mixtures comprising un-expanded micro-capsules and a plastisol or other suitable resins are applied to the substrate and subsequently heat treated to expand the micro-capsules within the coating. The expanded micro-capsules create an aesthetically pleasing surface texture in the coating while retaining the desired wear-resistant properties of the coating.Type: GrantFiled: February 20, 2002Date of Patent: January 11, 2005Assignee: Congoleum CorporationInventor: Richard C. MacQueen
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Patent number: 6838485Abstract: An emulsifier composition for treating marine cuttings, preferably in situ, to convert free hydrocarbons to isolated hydrocarbons; drill cuttings treated with the emulsifier composition; droplets of the emulsified free hydrocarbons; drill cuttings further treated with encapsulating material; and, isolated hydrocarbons comprising encapsulated droplets of free hydrocarbons and emulsifier.Type: GrantFiled: October 18, 2000Date of Patent: January 4, 2005Assignee: Baker Hughes IncorporatedInventor: Lirio Quintero
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Patent number: 6835397Abstract: The present invention is an encapsulated yeast composite comprising a core comprising yeast and a coating containing an emulsifiable lipid. The yeast includes Saccharomyces cerevisiae. The invention also relates to other encapsulated bioactive substance composites. The nature of the coating provides controlled release of the bioactive substance from the encapsulate. The encapsulated composites are useful in the production of food compositions, food products, and animal feed products.Type: GrantFiled: January 14, 2003Date of Patent: December 28, 2004Assignee: Balchem CorporationInventors: Phillip K. Lee, Paul H. Richardson
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Patent number: 6835334Abstract: The present invention is directed to a method for producing macrocapsules containing therein a plurality of microcapsules. In accordance with some embodiments of the present invention, the microcapsules contain a phase change material.Type: GrantFiled: March 8, 2004Date of Patent: December 28, 2004Assignee: Microtek Laboratories, Inc.Inventors: Danny Allen Davis, Ronald Lee Hart, Dale Ellis Work, David Russell Virgallito
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Patent number: 6835395Abstract: Lipidic compositions with superior characteristics for in vivo delivery of oligodeoxynucleotides (ODN) can easily and efficiently be made in the form of small multilamellar vesicles. The compositions contain a population of nucleic acid-containing lipid vesicles in a liquid carrier, and at least a portion of the lipid vesicles are small multilamellar vesicles. The small multilamellar vesicles are made from a lipid component including 20-30 mol % of an ionizable amino lipid such as DODAP, and a steric barrier lipid such as PEG-CerC14; and an oligodeoxynucleotide contained in the lumen or interlamellar spaces of the small multilamellar vesicles. The ODN and lipid components are preferably present in the small multilamellar vesicles in a mole ratio of from 0.15 to 0.25.Type: GrantFiled: September 1, 2000Date of Patent: December 28, 2004Assignee: The University of British ColumbiaInventors: Sean C. Semple, Sandra K. Klimuk, Troy O. Harasym, Nancy Dos Santos, Steven M. Ansell, Pieter R Cullis, Michael J. Hope, Peter Scherrer, Deirdre McIntosh, Kim F. Wong, Norbert Maurer
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Patent number: 6835394Abstract: The present invention provides biocompatible vesicles comprising semi-permeable, thin-walled encapsulating membranes which are formed in an aqueous solution, and which comprise one or more synthetic super-amphiphilic molecules. When at least one super-amphiphile molecule is a block copolymer, the resulting synthetic vesicle is termed a “polymersome.” The synthetic, reactive nature of the amphiphilic composition enables extensive, covalent cross-linking of the membrane, while maintaining semi-permeability. Cross-linking of the polymer building-block components provides mechanical control and long-term stability to the vesicle, thereby also providing a means of controlling the encapsulation or release of materials from the vesicle by modifying the composition of the membrane. Thus, the encapsulating membranes of the present invention are particularly suited for the reliable, durable and controlled transport, delivery and storage of materials.Type: GrantFiled: December 14, 1999Date of Patent: December 28, 2004Assignee: The Trustees of the University of PennsylvaniaInventors: Dennis E. Discher, Bohdana M. Discher, You-Yeon Won, James C-M. Lee, Frank S. Bates, Daniel A. Hammer
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Publication number: 20040234763Abstract: This invention provides a mounting method for reliably connecting mounting components electrically. Specifically, an anisotropically conductive adhesive can be composed of crushable microcapsules and a second liquid in which the microcapsules are dispersed. Each microcapsule encloses a first liquid and a conductive particle. The first liquid can react with the second liquid at normal temperatures to cure the second liquid. This anisotropically conductive adhesive can be applied on a flexible printed circuit (FPC). Then, a drive IC is mounted and pressed on the FPC to crush the microcapsules between electrode pads provided on the drive IC and electrode pads provided on the FPC, thereby bonding the electrode pads. Subsequently, the anisotropically conductive adhesive is heated to plasticize a capsule wall of each microcapsule, thereby bonding the drive IC and the FPC.Type: ApplicationFiled: March 30, 2004Publication date: November 25, 2004Applicant: SEIKO EPSON CORPORATIONInventor: Atsushi Saito
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Patent number: 6818296Abstract: A microcapsule having a mean diameter of from about 0.1 to about 5 mm, a membrane and a matrix containing at least one active principle wherein the microcapsule is the product of the process comprising the steps of (a) forming an aqueous matrix by heating an aqueous solution comprised of a gel former, a chitosan and active principle; (b) forming a dispersed matrix by adding the aqueous matrix in an oil phase; (c) contacting the dispersed matrix with an aqueous solution of an anionic polymer selected from the group consisting of a salt of alginic acid and an anionic chitosan derivative.Type: GrantFiled: April 4, 2002Date of Patent: November 16, 2004Assignee: Cognis Iberia S.L.Inventors: Josep Garces Garces, Josep-Lluis Viladot Petit
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Publication number: 20040224156Abstract: A waterproof heat-preservative film is formed by providing a melt of a waterproof material, mixing phase-change microcapsules with the melt to form a mixture, solidifying the mixture and pulverizing the solidified mixture to form particles containing phase-change microcapsules, and forming a film with the particles by means of extruding or blowing.Type: ApplicationFiled: May 6, 2003Publication date: November 11, 2004Applicant: CHENG LOONG CORPORATIONInventor: Chieh-Jen Wu
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Patent number: 6815472Abstract: A golf ball comprising a core; and a cover layer disposed concentrically about the core; wherein at least one of the core or the cover is formed of a polymer comprising lipid-based nanotubules in which an active compound is microencapsulated.Type: GrantFiled: February 5, 2003Date of Patent: November 9, 2004Assignee: Acushnet CompanyInventor: William B. Lacy
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Publication number: 20040219361Abstract: The invention relates to a super-paramagnetic composite particle with core/shell structure, preparation method and use thereof. The composite particle is consisted of a core portion and a shell portion coated on the surface of the core portion, wherein said core portion is 10-70% by weight and said shell portion is 30-90% by weight based on the total weight of the composite particle, and said core portion is consisted of magnetic particles of Fe3O4, &ggr;-Fe2O3 or other ferric oxides, or magnetic particles of ferrites of tervalent ferrum and bivalent manganese, nickel, zinc or copper, and the said shell portion is consisted of elementary gold or silver. The particle has an average diameter of 0.05-50 &mgr;m. The preparation method comprises preparing the core portion magnetic particle by chemical co-precipitation and depositing gold or silver to coat the magnetic particle by chemical reduction.Type: ApplicationFiled: April 28, 2004Publication date: November 4, 2004Applicant: Shanxi Lifegen Co., Ltd.Inventors: Yali Cui, Chao Chen, Qiong Wang, Wenli Hui
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Publication number: 20040201117Abstract: A particle coated with a nonlamellar material such as a nonlamellar crystalline material, a nonlamellar amorphous material, or a nonlamellar semi-crystalline material includes an internal matrix core having at least one a nanostructured liquid phase, or at least on nanostructured liquid crystalline phase or a combination of the two is used for the delivery of active agents such as pharmaceuticals, nutrients, pesticides, etc.Type: ApplicationFiled: July 23, 2003Publication date: October 14, 2004Inventor: David Anderson
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Publication number: 20040169298Abstract: Provided are a microcapsule and a production method thereof using a low-toxicity polymer substrate which can be produced regardless of a core material's water or oil solubility, without using gelatin or an organic solvent viewed as having a problem with safety. Specifically, provided is a microcapsule comprising oil-based core material which is immiscible with water; and shell material which comprises gum arabic and an enteric anionic cellulose derivative. Also provided is a method for producing a microcapsule comprising steps of suspending an oil-based water-immiscible core material in an aqueous solution of gum arabic, and then adding an aqueous alkaline solution of an enteric anionic cellulose derivative.Type: ApplicationFiled: November 18, 2003Publication date: September 2, 2004Applicant: Shin-Etsu Chemical Co., Ltd.Inventors: Miyuki Fukasawa, Kazuhisa Hayakawa
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Patent number: 6777486Abstract: A vibration damping silicone composition with excellent long term storage stability and vibration damping ability contains as components (A) a silicone oil, (B) hollow particles of an organic resin having an inorganic material powder supported on its surfaces, and (C) a solid inorganic material powder.Type: GrantFiled: June 26, 2001Date of Patent: August 17, 2004Assignee: Dow Corning Toray Silicone Co., Ltd.Inventors: Hideki Kobayashi, Masayuki Hayashi
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Transparent film-coated substrate, coating liquid for transparent film formation, and display device
Patent number: 6777069Abstract: The transparent film-coated substrate includes a substrate and a transparent coating film formed on the surface of the substrate, the transparent coating film comprising (i) a matrix containing a silicone having a fluorine-substituted alkyl group, and (ii) inorganic compound particles comprising a shell, and a porous matter or a cavity enclosed therein, wherein the porous matter or the cavity remains unchanged in the formed transparent coating film.Type: GrantFiled: November 8, 2002Date of Patent: August 17, 2004Assignees: Kabushiki Kaisha Toshiba, Asahi Glass Co., Ltd., Catalysts & Chemicals Industries Co., Ltd.Inventors: Takeo Ito, Hidemi Matsuda, Yoshimi Otani, Kazuhiko Yui, Toshiharu Hirai, Hiroyasu Nishida, Michio Komatsu -
Patent number: 6774063Abstract: The present invention is a slip resistant nonwoven material. The material can be useful for surgical or clean room environments. The nonwoven is coated with microencapsulated adhesive. The microcapsule coated nonwoven is resistant for slippage. The substrate in preferred embodiments is fashioned into articles such as slip resistant table coverings or protective articles such as footwear.Type: GrantFiled: February 19, 2002Date of Patent: August 10, 2004Assignee: Appleton Papers Inc.Inventors: Michael Paul Bouchette, Kevin Patrick Coffey, Robert Josef Franda
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Patent number: 6773719Abstract: The present invention provides a liposomal composition for treating dislipidemias in human subjects, a method of using a liposomal composition, and devices and modes of operation of the devices and of the compositions, and kits related thereto. The invention provides for the reverse transport of cholesterol from peripheral tissues to the liver in a warm blood mammal while controlling plasma atherogenic lipoprotein concentrations, including LDL concentrations. A method described above and mode of operation of the devices includes the stop of administering an effective amount of a multiplicity of acceptors comprised of phospholipids substantially free of sterol. A method described above optionally includes the stop of periodically assaying atherogenic lipoprotein concentrations with an assay during the treatment period to assess atherogenic lipoprotein concentrations and obtain an atherogenic lipoprotein profile.Type: GrantFiled: August 7, 2001Date of Patent: August 10, 2004Assignees: Esperion LUV Development, Inc., The University of British ColumbiaInventors: Wendi V. Rodrigueza, Kevin Jon Williams, Michael J. Hope
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Patent number: 6767637Abstract: A method for generating a plurality of drug-containing microcapsules employs one or more atomizers to form the microcapsules by the phenomenon of solvent exchange. A plurality of microdroplets of an aqueous solution is contacted with a plurality of microdroplets containing a polymer dissolved in a hydrophilic solvent under conditions whereby the polymer solution envelops the aqueous microdroplet. Exchange of solvent molecules between the aqueous core and its polymer-containing shell deposits the polymer as a membrane around the aqueous core. A preferred atomizer is a coaxial ultrasonic atomizer. Microcapsules can be generated in air as well as when submersed in a collection bath. Desired properties of the microcapsules, e.g., controlled release, can be achieved by providing protective excipients within the aqueous core, providing a hydrophilic polymer capable of undergoing a sol-to-gel transition within the aqueous core, optimizing selection of the polymer solvent, adjusting relative flow rates, and the like.Type: GrantFiled: March 19, 2003Date of Patent: July 27, 2004Assignee: Purdue Research FoundationInventors: Kinam Park, Yoon Yeo
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Patent number: 6753083Abstract: A particulate composition comprising particles having a core comprising a hydrophobic polymer within a shell, characterised in that the shell comprises a semi-permeable membrane. Particulate composition can be used for making a stable dispersion of particles uniformly distributed throughout a first hydrophobic liquid, wherein the particles comprise a core within a shell and the core comprises a hydrophobic polymer into has been imbibed a second hydrophobic liquid, Compositions can be used to encapsulate active substances and may be used in sustained release mechanisms.Type: GrantFiled: October 18, 2001Date of Patent: June 22, 2004Assignee: Ciba Specialty Chemicals Water Treatments Ltd.Inventors: Kishor Kumar Mistry, Janine Andrea Preston, Kenneth Charles Symes
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Patent number: 6743638Abstract: A process for detecting an analyte which process comprises (a) contacting a sample suspected of containing said analyte with a containment means comprising a barrier which separates signal generating reagents from said sample, in the presence of an element which interacts specifically with said analyte, under conditions whereby interaction between the analyte and the said element results in activation of the signal generating reagents within the containment means on the side of the barrier opposite to the sample, and (b) detecting any signal generated and retained within the containment means from the sample side of the barrier. The process of the invention provides for sensitive detection of very small numbers of analyte materials using measurement techniques which include counting methods such as flow cytometry.Type: GrantFiled: July 12, 2000Date of Patent: June 1, 2004Assignee: The Secretary of State for DefenceInventors: Marina Tsilosani, David J Clarke, Christopher J Lloyd, Stephen Nicklin, Harmesh S Aojula, Michael T Wilson
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Patent number: 6733857Abstract: The present invention relates to a material for repairing damaged painted surfaces, wherein the material includes a paint layer which is capable of deformation and which is made of microcapsules held together by a binder. The paint is contained in the microcapsules in the form of paint droplets or powdered paint particles. The microcapsules and/or the binder are preferably made from a material that becomes tacky under the action of heat.Type: GrantFiled: July 27, 2001Date of Patent: May 11, 2004Assignee: Deotexis, Inc.Inventor: Gerold Tebbe
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Patent number: 6727203Abstract: A method capable of producing, with industrially realizable production efficiency, microcapsules whose particle diameters are small and whose particle diameter distribution is limited, specifically microcapsules for a heat-sensitive recording material, and a heat-sensitive recording material including the thus produced microcapsules. In this method, microcapsules are produced by the steps of preparing an emulsion from an oil phase that contains a material to be micro-encapsulated and a microcapsule wall material, and an aqueous phase, and micro-encapsulating the materials by using the emulsion, the emulsion preparing step being conducted by using a microreactor having channels whose equivalent diameter is no more than 1 mm, and a heat-sensitive recording material having the thus obtained microcapsules is also provided.Type: GrantFiled: February 12, 2002Date of Patent: April 27, 2004Assignee: Fuji Photo Film Co., Ltd.Inventor: Kimio Ichikawa
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Publication number: 20040074089Abstract: An uncured epoxy adhesive comprising a resin component, a hardener component, and a microencapsulated accelerator component. The microencapsulated accelerator component comprises an infrared absorber, an accelerator and a wall that covers substantially the entire surface of the accelerator. The epoxy adhesive is cured by exposing it to infrared energy. The infrared energy is absorbed by the infrared absorber which disintegrates the wall and allows the accelerator to come into contact with the other adhesive components and initiate the curing polymerization reaction.Type: ApplicationFiled: October 16, 2002Publication date: April 22, 2004Applicant: Cookson Electronics, Inc.Inventor: Kenneth B. Gilleo
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Patent number: 6723671Abstract: Fragrance emitting articles are provided along with methods of making and using the same. The fragrance emitting articles provided contain microcapsules of a fragrance, which microcapsules are associated with the fragrance emitting article without the addition of a binder. The invention also relates to methods of making the subject fragrance emitting articles and methods of using those articles.Type: GrantFiled: April 13, 2001Date of Patent: April 20, 2004Assignee: Lavipharm Laboratories Inc.Inventors: Yelena Zolotarsky, David O'Halloran, Florence Bernard, Pradeep Thaker
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Publication number: 20040071967Abstract: This invention provides water-based compositions, particularly coating, ink, fountain solution and agricultural compositions, manifesting reduced equilibrium and dynamic surface tension by the incorporation of a surface tension reducing amount of an acetylenic diol ethylene oxide/propylene oxide adduct of the structure where r and f are 1 or 2, (n+m) is 1 to 30 and (p+q) is 1 to 30. Use of such adducts as surfactants in photoresist developer/electronics cleaning compositions is particularly advantageous.Type: ApplicationFiled: July 11, 2003Publication date: April 15, 2004Inventor: Won-Mok Lee
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Patent number: 6716526Abstract: A composition comprising particles which comprise a core material within a polymeric shell, wherein the core material comprises a hydrophobic substance, characterized in that the polymeric shell comprises a copolymer formed from a monomer blend which comprises, A) 30 to 90% by weight methacrylic acid B) 10 to 70% by weight alkyl ester of (meth)acrylic acid which is capable of forming a homopolymer of glass transition temperature in excess of 60° C. and C) 0 to 40% by weight other ethylenically unsaturated monomer. The core material can comprise an active ingredient selected from the group consisting of UV absorbers, UV reflectors, pigments, dyes, colorants, scale inhibitors, corrosion inhibitors, antioxidants, pour point depressants, wax deposition inhibitors, dispersants, flame retardants, biocides, active dye tracer materials and phase change materials. The composition has the advantage that the polymeric shell is highly impermeable to the core material even at elevated temperatures.Type: GrantFiled: July 17, 2002Date of Patent: April 6, 2004Assignee: Ciba Specialty Chemicals Water Treatments Ltd.Inventors: Rachel Clare Weston, Howard Roger Dungworth
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Patent number: 6716793Abstract: An image-recording composition comprising: a microcapsule enclosing a leuco-dye; a phenol color-developing agent; and a reaction-accelerating agent catalyzing a color-developing reaction between the leuco-dye and the phenol color-developing agent, the reaction-accelerating agent being an organic compound having at least two carboxyl groups. An image-recording sheet comprising a substrate and a color-developing layer disposed by applying the image-recording composition to the substrate is also provided.Type: GrantFiled: May 17, 2001Date of Patent: April 6, 2004Assignee: Pentax CorporationInventors: Yukio Kubota, Minoru Suzuki, Kazuyuki Shimbo
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Patent number: 6706353Abstract: An image-forming substrate has a sheet of paper, and a layer of microcapsules coated over the paper sheet. The microcapsule layer contains at least one type of microcapsules filled with a liquid dye, and a shell wall of each of the microcapsules is composed of resin that exhibits a temperature/pressure characteristic such that, when each of the microcapsules is squashed under a predetermined pressure at a predetermined temperature, the liquid dye seeps from the squashed microcapsule.Type: GrantFiled: August 27, 1998Date of Patent: March 16, 2004Assignee: Pentax CorporationInventor: Minoru Suzuki
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Patent number: 6706280Abstract: Novel compounds of formula in which R1 and R2 are phospholipid fatty acid residues and A is an aliphatic and/or cycloaliphatic hydrocarbon chain optionally substituted by hydroxy and/or further carboxylic functions. The novel compounds are useful for making liposomes of enhanced stability and entrapping capacity.Type: GrantFiled: August 16, 1999Date of Patent: March 16, 2004Assignee: Bracco Research S.A.Inventors: Hervé Tournier, Bernard Lamy
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Patent number: 6703127Abstract: The present invention is directed to thermal energy storage compositions comprising macrocapsules containing therein a plurality of microcapsules and to methods for producing macrocapsules containing microcapsules. In accordance with some embodiments of the present invention, the microcapsules contain a phase change material.Type: GrantFiled: September 27, 2001Date of Patent: March 9, 2004Assignee: Microtek Laboratories, Inc.Inventors: Danny Allen Davis, Ronald Lee Hart, Dale Ellis Work, David Russell Virgallito
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Publication number: 20040043212Abstract: A nonwoven textile having reversible enhanced thermal control properties, the material comprising: a bat or web bonded by polymeric binder containing thermal control material within the interior of the bat or web, wherein the thermal control material is dispersed throughout the interior of the polymeric binder, and wherein the thermal control material is substantially entirely within the interior of the nonwoven textile.Type: ApplicationFiled: August 13, 2003Publication date: March 4, 2004Inventors: Peter Grynaeus, Duncan Russell, Terry O'Regan, David S. Dietel, Susan Gwynneth Johnson
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Patent number: 6699499Abstract: Disclosed is a new structural class of amphiphilic molecules which incorporate a hydrophilic material or polymer attached, at spatially distinct sites, to at least two hydrophobic residues. Certain of the amphiphilic molecules comprise a plurality of hydrophobic moieties. All such amphiphilic molecules have a common structural motif and, in contact with water, display surface activity and self-assemble into multimolecular aggregates and liquid crystalline phases. Also disclosed are enhanced stability liposomes that incorporate such amphiphilic molecules via unique interactions, and methods of using such formulations in a variety of applications including drug delivery, nutrition, bio-diagnostics, cosmetics, blood products and related applications.Type: GrantFiled: June 11, 2001Date of Patent: March 2, 2004Assignee: Nutrimed BiotechInventor: Rajindra Aneja
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Patent number: 6699952Abstract: A modular cytomimetic biocompatible biomaterial, comprising a phospholipid or phospholipid derivative comprising various functional groups (e.g., lipid, peptide, sugar) having specific chemical properties which can function as a modular surface design unit to be incorporated or appended to a desired substrate (e.g., a polymer or a metal) on which it is then polymerized in situ, thereby contributing new or specified biochemical characteristics to the polymerized and stabilized biomaterial.Type: GrantFiled: June 2, 2003Date of Patent: March 2, 2004Assignee: Emory UniversityInventors: Elliot L. Chaikof, Kacey G. Marra, John H. Chon
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Patent number: 6689466Abstract: A stabilized phase change composition comprises a phase change material and a stabilizing agent selected from the group consisting of antioxidants and thermal stabilizers. The stabilizing agent provides oxidative or thermal stabilization to the phase change material. The stabilized phase change composition may be used or incorporated in a variety of processes (e.g., melt spinning processes, extrusion processes, injection molding processes, and so forth) to form articles having enhanced reversible thermal properties. Exemplary articles that may be formed include, by way of example and not by limitation, synthetic fibers (e.g., nylon fibers, polyester fibers, polyethylene fibers, polypropylene fibers, and multi-component fibers), fabric materials, textiles, films, foams, sheets, pellets, granules, rods, and injection molded articles.Type: GrantFiled: September 21, 2001Date of Patent: February 10, 2004Assignee: Outlast Technologies, Inc.Inventor: Mark H. Hartmann
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Publication number: 20040022990Abstract: The present invention relates to compositions and methods for providing extended release of fragrances and other agents into a variety of materials, including carpets, rugs, fibrous mats, furniture, drapery, and similar products and materials.Type: ApplicationFiled: April 3, 2003Publication date: February 5, 2004Inventor: Arif Sitabkhan
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Publication number: 20040018359Abstract: The invention relates to preserving the properties of active particles through use of an encapsulant which may be removable. The encapsulant may protect the active particles against premature deactivation. If desired, the encapsulant may be removed to rejuvenate the active particles. Various processes can be implemented to introduce encapsulated particles to embedding substances which may be used in various products.Type: ApplicationFiled: June 12, 2003Publication date: January 29, 2004Inventor: Gregory W. Haggquist
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Publication number: 20040012105Abstract: The invention relates to microspheres with a narrow distribution of particle size and a uniform spherical shape, consisting of a partially or completely cross-linked polymer material. The invention also relates to a method for producing said microspheres and to the use thereof.Type: ApplicationFiled: August 6, 2003Publication date: January 22, 2004Inventors: Holger Deppe, Hanns Wurziger, Andreas Schober, Egbert Brandau, Thorsten Brandau, Esther Daldrop
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Publication number: 20040012106Abstract: The present invention provides: a microcapsule composition for electrophoretic displays; a production process for the microcapsule composition for the electrophoretic displays; a production process for a sheet for the electrophoretic displays; and a handling method for microcapsules for the electrophoretic displays; wherein the microcapsule composition contains microcapsules and, when used for the electrophoretic displays, can make them as excellent as conventional in various performances (e.g. longtime stability of displaying, respondability of displaying, contrast, and number of times of display rewritability) and, particularly above all, can make the electrophoretic displays exhibit a very high performance as to the contrast.Type: ApplicationFiled: July 3, 2003Publication date: January 22, 2004Inventors: Sadao Kanbe, Hideyuki Kawai, Mitsuo Kushino, Makoto Matsumoto
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Patent number: RE38459Abstract: An injectable physiologically acceptable aqueous phase fluorocarbon emulsion, which has substantially no free fluorocarbon, has an excellent stability is prepared by a process of the invention. Typically, more than about 99.8 wt. % of the fluorocarbon remains in the size range of about 0.2 to 0.4 microns even after being stored at room temperature for one year or more in sealed containers under a non-oxidizing atmosphere. The emulsion is useful in medical applications, for example, coronary angioplasty, cancer therapy, among others.Type: GrantFiled: January 21, 1999Date of Patent: March 9, 2004Assignee: Thomas Jefferson UniversityInventors: Stuart Raynolds, Robert H. Dettre